,question,answer,question_new
2121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of TXNIP. Does perturbing SLC39A7 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of TXNIP. Does perturbing SLC39A7 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of SDF4. Does this perturbation cause a significant change in SDF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of SDF4. Does this perturbation cause a significant change in SDF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3583,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP3-465N24.6 expression is observed. Does this perturbation lead to a significant difference in RP3-465N24.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP3-465N24.6 expression is observed. Does this perturbation lead to a significant difference in RP3-465N24.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4528,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ATF7IP2 expression. Decide whether this perturbation leads to a significant alteration in ATF7IP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ATF7IP2 expression. Decide whether this perturbation leads to a significant alteration in ATF7IP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RGS20. Does perturbing MARS lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RGS20. Does perturbing MARS lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3573,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and APOBEC3D expression is observed. Does this perturbation lead to a significant difference in APOBEC3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and APOBEC3D expression is observed. Does this perturbation lead to a significant difference in APOBEC3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ZNF429 expression is observed. Does this perturbation lead to a significant difference in ZNF429 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ZNF429 expression is observed. Does this perturbation lead to a significant difference in ZNF429 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of GALNT7. Does this perturbation cause a significant change in GALNT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of GALNT7. Does this perturbation cause a significant change in GALNT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3020,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Does this perturbation cause a significant change in HIST1H2AC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Does this perturbation cause a significant change in HIST1H2AC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
600,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Does this perturbation cause a significant change in PBDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Does this perturbation cause a significant change in PBDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of RNF19A. Does this perturbation cause a significant change in RNF19A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of RNF19A. Does this perturbation cause a significant change in RNF19A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in DOCK8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in DOCK8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AFF1. Does this perturbation cause a significant change in AFF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AFF1. Does this perturbation cause a significant change in AFF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and SEC23IP expression is measured. Determine whether SEC23IP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and SEC23IP expression is measured. Determine whether SEC23IP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and KIF4A expression is quantified. Does this perturbation result in a significant change in KIF4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and KIF4A expression is quantified. Does this perturbation result in a significant change in KIF4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3200,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and KLF3 expression is quantified. Does this perturbation result in a significant change in KLF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and KLF3 expression is quantified. Does this perturbation result in a significant change in KLF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4783,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PDE3B expression is observed. Does this perturbation lead to a significant difference in PDE3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PDE3B expression is observed. Does this perturbation lead to a significant difference in PDE3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Determine whether AC104532.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Determine whether AC104532.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1130,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Determine whether RNF139-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Determine whether RNF139-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in SLC27A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in SLC27A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of F2RL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of F2RL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CDT1 expression is quantified. Does this perturbation result in a significant change in CDT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CDT1 expression is quantified. Does this perturbation result in a significant change in CDT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1233,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and SRP72 expression is observed. Does this perturbation lead to a significant difference in SRP72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and SRP72 expression is observed. Does this perturbation lead to a significant difference in SRP72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ROCK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ROCK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of LIMS1. Does perturbing SRP72 lead to a significant change in LIMS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of LIMS1. Does perturbing SRP72 lead to a significant change in LIMS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3633,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and SOBP expression is observed. Does this perturbation lead to a significant difference in SOBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and SOBP expression is observed. Does this perturbation lead to a significant difference in SOBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HIST1H3D expression is quantified. Does this perturbation result in a significant change in HIST1H3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HIST1H3D expression is quantified. Does this perturbation result in a significant change in HIST1H3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3823,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and OBSCN expression is observed. Does this perturbation lead to a significant difference in OBSCN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and OBSCN expression is observed. Does this perturbation lead to a significant difference in OBSCN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1018,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor KCNE3 expression. Decide whether this perturbation leads to a significant alteration in KCNE3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor KCNE3 expression. Decide whether this perturbation leads to a significant alteration in KCNE3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDKN2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDKN2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of CENPF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of CENPF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3800,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2830,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Does this perturbation cause a significant change in EXO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Does this perturbation cause a significant change in EXO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3720,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Does this perturbation cause a significant change in ARHGAP11A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Does this perturbation cause a significant change in ARHGAP11A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of TIPARP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of TIPARP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4458,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
61,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RIOK3. Does perturbing ZNF326 lead to a significant change in RIOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RIOK3. Does perturbing ZNF326 lead to a significant change in RIOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Determine whether UQCRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Determine whether UQCRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of FOXO6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of FOXO6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2173,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and LRRC4B expression is observed. Does this perturbation lead to a significant difference in LRRC4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and LRRC4B expression is observed. Does this perturbation lead to a significant difference in LRRC4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2860,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Does this perturbation cause a significant change in PIK3IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Does this perturbation cause a significant change in PIK3IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Determine whether HRK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Determine whether HRK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Determine whether F2RL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Determine whether F2RL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of EIF4B. Does perturbing TMED2 lead to a significant change in EIF4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of EIF4B. Does perturbing TMED2 lead to a significant change in EIF4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CTCFL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CTCFL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3408,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor C3AR1 expression. Decide whether this perturbation leads to a significant alteration in C3AR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor C3AR1 expression. Decide whether this perturbation leads to a significant alteration in C3AR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP11-119J18.1. Does perturbing MRPL39 lead to a significant change in RP11-119J18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP11-119J18.1. Does perturbing MRPL39 lead to a significant change in RP11-119J18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CST7 expression is measured. Determine whether CST7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CST7 expression is measured. Determine whether CST7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in HOTAIRM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in HOTAIRM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3918,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor TFPI expression. Decide whether this perturbation leads to a significant alteration in TFPI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor TFPI expression. Decide whether this perturbation leads to a significant alteration in TFPI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and POLR2J3 expression is quantified. Does this perturbation result in a significant change in POLR2J3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and POLR2J3 expression is quantified. Does this perturbation result in a significant change in POLR2J3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC096559.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC096559.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Determine whether USP37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Determine whether USP37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of RNF139-AS1. Does this perturbation cause a significant change in RNF139-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of RNF139-AS1. Does this perturbation cause a significant change in RNF139-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4253,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and PAK1IP1 expression is observed. Does this perturbation lead to a significant difference in PAK1IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and PAK1IP1 expression is observed. Does this perturbation lead to a significant difference in PAK1IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1450,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Does this perturbation cause a significant change in LRIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Does this perturbation cause a significant change in LRIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
220,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Does this perturbation cause a significant change in CASP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Does this perturbation cause a significant change in CASP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
613,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and HP1BP3 expression is observed. Does this perturbation lead to a significant difference in HP1BP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and HP1BP3 expression is observed. Does this perturbation lead to a significant difference in HP1BP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in CTD-2587M2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in CTD-2587M2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RAI14. Does this perturbation cause a significant change in RAI14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RAI14. Does this perturbation cause a significant change in RAI14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of NUFIP2. Does perturbing GBF1 lead to a significant change in NUFIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of NUFIP2. Does perturbing GBF1 lead to a significant change in NUFIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Determine whether PSMC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Determine whether PSMC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1648,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor SERPINH1 expression. Decide whether this perturbation leads to a significant alteration in SERPINH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor SERPINH1 expression. Decide whether this perturbation leads to a significant alteration in SERPINH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of P4HB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of P4HB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in SSBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in SSBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EIF3A expression is measured. Determine whether EIF3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EIF3A expression is measured. Determine whether EIF3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
178,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TKTL1 expression. Decide whether this perturbation leads to a significant alteration in TKTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TKTL1 expression. Decide whether this perturbation leads to a significant alteration in TKTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in FAM114A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in FAM114A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Determine whether SLFNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Determine whether SLFNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of SOBP. Does perturbing EIF2S1 lead to a significant change in SOBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of SOBP. Does perturbing EIF2S1 lead to a significant change in SOBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RDH10. Does this perturbation cause a significant change in RDH10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RDH10. Does this perturbation cause a significant change in RDH10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1783,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and KCNH7 expression is observed. Does this perturbation lead to a significant difference in KCNH7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and KCNH7 expression is observed. Does this perturbation lead to a significant difference in KCNH7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Determine whether PLA2G15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Determine whether PLA2G15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IDH3A. Does perturbing MANF lead to a significant change in IDH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IDH3A. Does perturbing MANF lead to a significant change in IDH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Determine whether GPRC5C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Determine whether GPRC5C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ITGB2 expression is quantified. Does this perturbation result in a significant change in ITGB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ITGB2 expression is quantified. Does this perturbation result in a significant change in ITGB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and TGOLN2 expression is quantified. Does this perturbation result in a significant change in TGOLN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and TGOLN2 expression is quantified. Does this perturbation result in a significant change in TGOLN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2050,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ERV3-1 expression is quantified. Does this perturbation result in a significant change in ERV3-1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ERV3-1 expression is quantified. Does this perturbation result in a significant change in ERV3-1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CTD-2020K17.1. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CTD-2020K17.1. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
953,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HERC2 expression is observed. Does this perturbation lead to a significant difference in HERC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HERC2 expression is observed. Does this perturbation lead to a significant difference in HERC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Determine whether TTC18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Determine whether TTC18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HIST1H1E expression is measured. Determine whether HIST1H1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HIST1H1E expression is measured. Determine whether HIST1H1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SLC37A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SLC37A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Determine whether DDX3X shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Determine whether DDX3X shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HIST1H3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HIST1H3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
408,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor RP11-90P5.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-90P5.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor RP11-90P5.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-90P5.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
518,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PDE4D expression. Decide whether this perturbation leads to a significant alteration in PDE4D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PDE4D expression. Decide whether this perturbation leads to a significant alteration in PDE4D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KCNQ1OT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KCNQ1OT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Determine whether KCNH7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Determine whether KCNH7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ARHGAP30 expression is quantified. Does this perturbation result in a significant change in ARHGAP30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ARHGAP30 expression is quantified. Does this perturbation result in a significant change in ARHGAP30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
373,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HMGCS1 expression is observed. Does this perturbation lead to a significant difference in HMGCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HMGCS1 expression is observed. Does this perturbation lead to a significant difference in HMGCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
35,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in CASP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in CASP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1178,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in PSORS1C1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in PSORS1C1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of CRNDE. Does perturbing TMEM167A lead to a significant change in CRNDE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of CRNDE. Does perturbing TMEM167A lead to a significant change in CRNDE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and ZEB1 expression is measured. Determine whether ZEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and ZEB1 expression is measured. Determine whether ZEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of C19orf59. Does perturbing HSPA9 lead to a significant change in C19orf59 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of C19orf59. Does perturbing HSPA9 lead to a significant change in C19orf59 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PDE4D. Does this perturbation cause a significant change in PDE4D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PDE4D. Does this perturbation cause a significant change in PDE4D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Determine whether TKTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Determine whether TKTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
70,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Does this perturbation cause a significant change in CEBPG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Does this perturbation cause a significant change in CEBPG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and NOX5 expression is quantified. Does this perturbation result in a significant change in NOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and NOX5 expression is quantified. Does this perturbation result in a significant change in NOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and RP11-666A20.4 expression is quantified. Does this perturbation result in a significant change in RP11-666A20.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and RP11-666A20.4 expression is quantified. Does this perturbation result in a significant change in RP11-666A20.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Determine whether GPR146 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Determine whether GPR146 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and SERPINF2 expression is quantified. Does this perturbation result in a significant change in SERPINF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and SERPINF2 expression is quantified. Does this perturbation result in a significant change in SERPINF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ATF6 expression is quantified. Does this perturbation result in a significant change in ATF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ATF6 expression is quantified. Does this perturbation result in a significant change in ATF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and TMOD3 expression is measured. Determine whether TMOD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and TMOD3 expression is measured. Determine whether TMOD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in KCNJ13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in KCNJ13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
89,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and PHF3 expression is measured. Determine whether PHF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and PHF3 expression is measured. Determine whether PHF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and EP400 expression is quantified. Does this perturbation result in a significant change in EP400 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and EP400 expression is quantified. Does this perturbation result in a significant change in EP400 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PTAR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PTAR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of PDK2. Does perturbing DERL2 lead to a significant change in PDK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of PDK2. Does perturbing DERL2 lead to a significant change in PDK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AC015987.1. Does perturbing NEDD8 lead to a significant change in AC015987.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AC015987.1. Does perturbing NEDD8 lead to a significant change in AC015987.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Determine whether CRNDE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Determine whether CRNDE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PSMD14 expression is measured. Determine whether PSMD14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PSMD14 expression is measured. Determine whether PSMD14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4308,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor GCKR expression. Decide whether this perturbation leads to a significant alteration in GCKR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor GCKR expression. Decide whether this perturbation leads to a significant alteration in GCKR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ASPM. Does this perturbation cause a significant change in ASPM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ASPM. Does this perturbation cause a significant change in ASPM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and KCNJ13 expression is quantified. Does this perturbation result in a significant change in KCNJ13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and KCNJ13 expression is quantified. Does this perturbation result in a significant change in KCNJ13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2378,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor PPP4R2 expression. Decide whether this perturbation leads to a significant alteration in PPP4R2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor PPP4R2 expression. Decide whether this perturbation leads to a significant alteration in PPP4R2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of GS1-166A23.1. Does perturbing HSPA5 lead to a significant change in GS1-166A23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of GS1-166A23.1. Does perturbing HSPA5 lead to a significant change in GS1-166A23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4623,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KCNQ1OT1 expression is observed. Does this perturbation lead to a significant difference in KCNQ1OT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KCNQ1OT1 expression is observed. Does this perturbation lead to a significant difference in KCNQ1OT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4608,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor STARD9 expression. Decide whether this perturbation leads to a significant alteration in STARD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor STARD9 expression. Decide whether this perturbation leads to a significant alteration in STARD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of CASP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of CASP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and MS4A6E expression is measured. Determine whether MS4A6E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and MS4A6E expression is measured. Determine whether MS4A6E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4343,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and HIST1H1D expression is observed. Does this perturbation lead to a significant difference in HIST1H1D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and HIST1H1D expression is observed. Does this perturbation lead to a significant difference in HIST1H1D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5133,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CTC-308K20.1 expression is observed. Does this perturbation lead to a significant difference in CTC-308K20.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CTC-308K20.1 expression is observed. Does this perturbation lead to a significant difference in CTC-308K20.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
13,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3258,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of PRRC2B. Does this perturbation cause a significant change in PRRC2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of PRRC2B. Does this perturbation cause a significant change in PRRC2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4518,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor HM13 expression. Decide whether this perturbation leads to a significant alteration in HM13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor HM13 expression. Decide whether this perturbation leads to a significant alteration in HM13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4108,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor LINC00938 expression. Decide whether this perturbation leads to a significant alteration in LINC00938 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor LINC00938 expression. Decide whether this perturbation leads to a significant alteration in LINC00938 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PAXBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PAXBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of RP11-95O2.5. Does this perturbation cause a significant change in RP11-95O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of RP11-95O2.5. Does this perturbation cause a significant change in RP11-95O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Determine whether RNF8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Determine whether RNF8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
940,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Does this perturbation cause a significant change in RP11-789C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Does this perturbation cause a significant change in RP11-789C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3028,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor HIST1H2AC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor HIST1H2AC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4530,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Does this perturbation cause a significant change in RP11-304M2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Does this perturbation cause a significant change in RP11-304M2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and NTRK1 expression is quantified. Does this perturbation result in a significant change in NTRK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and NTRK1 expression is quantified. Does this perturbation result in a significant change in NTRK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4148,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2668,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ASPM expression. Decide whether this perturbation leads to a significant alteration in ASPM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ASPM expression. Decide whether this perturbation leads to a significant alteration in ASPM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4040,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Does this perturbation cause a significant change in SNHG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Does this perturbation cause a significant change in SNHG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2363,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and FYTTD1 expression is observed. Does this perturbation lead to a significant difference in FYTTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and FYTTD1 expression is observed. Does this perturbation lead to a significant difference in FYTTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and AC104532.4 expression is quantified. Does this perturbation result in a significant change in AC104532.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and AC104532.4 expression is quantified. Does this perturbation result in a significant change in AC104532.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of SLC27A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of SLC27A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of MBNL1. Does this perturbation cause a significant change in MBNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of MBNL1. Does this perturbation cause a significant change in MBNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2430,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Does this perturbation cause a significant change in RP13-216E22.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Does this perturbation cause a significant change in RP13-216E22.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PDE3B. Does this perturbation cause a significant change in PDE3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PDE3B. Does this perturbation cause a significant change in PDE3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ARHGAP6. Does perturbing MTHFD1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ARHGAP6. Does perturbing MTHFD1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PSMD14. Does perturbing SARS lead to a significant change in PSMD14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PSMD14. Does perturbing SARS lead to a significant change in PSMD14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2758,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RP11-685N10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-685N10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RP11-685N10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-685N10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2848,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of C9orf64. Does perturbing DDOST lead to a significant change in C9orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of C9orf64. Does perturbing DDOST lead to a significant change in C9orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in C1GALT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in C1GALT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of SSBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of SSBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and DOCK8 expression is measured. Determine whether DOCK8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and DOCK8 expression is measured. Determine whether DOCK8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TSPAN33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TSPAN33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is quantified. Does this perturbation result in a significant change in RP11-138C9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is quantified. Does this perturbation result in a significant change in RP11-138C9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-499F3.2. Does this perturbation cause a significant change in RP11-499F3.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-499F3.2. Does this perturbation cause a significant change in RP11-499F3.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3498,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor DST expression. Decide whether this perturbation leads to a significant alteration in DST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor DST expression. Decide whether this perturbation leads to a significant alteration in DST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3878,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor C9orf64 expression. Decide whether this perturbation leads to a significant alteration in C9orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor C9orf64 expression. Decide whether this perturbation leads to a significant alteration in C9orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in NOSTRIN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in NOSTRIN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of SKIL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of SKIL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
860,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Does this perturbation cause a significant change in ESCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Does this perturbation cause a significant change in ESCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4480,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of LAMP2. Does perturbing SPCS3 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of LAMP2. Does perturbing SPCS3 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and IL8 expression is measured. Determine whether IL8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and IL8 expression is measured. Determine whether IL8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
278,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DUT expression. Decide whether this perturbation leads to a significant alteration in DUT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DUT expression. Decide whether this perturbation leads to a significant alteration in DUT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1748,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor RPL39 expression. Decide whether this perturbation leads to a significant alteration in RPL39 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor RPL39 expression. Decide whether this perturbation leads to a significant alteration in RPL39 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and LTBP1 expression is quantified. Does this perturbation result in a significant change in LTBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and LTBP1 expression is quantified. Does this perturbation result in a significant change in LTBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1288,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of VIMP. Does perturbing COPZ1 lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of VIMP. Does perturbing COPZ1 lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Determine whether PTBP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Determine whether PTBP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IFT27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IFT27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4998,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor ZCCHC11 expression. Decide whether this perturbation leads to a significant alteration in ZCCHC11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor ZCCHC11 expression. Decide whether this perturbation leads to a significant alteration in ZCCHC11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of RP11-146D12.2. Does this perturbation cause a significant change in RP11-146D12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of RP11-146D12.2. Does this perturbation cause a significant change in RP11-146D12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and WHAMM expression is quantified. Does this perturbation result in a significant change in WHAMM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and WHAMM expression is quantified. Does this perturbation result in a significant change in WHAMM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3743,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA0922 expression is observed. Does this perturbation lead to a significant difference in KIAA0922 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA0922 expression is observed. Does this perturbation lead to a significant difference in KIAA0922 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and SPINK5 expression is quantified. Does this perturbation result in a significant change in SPINK5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and SPINK5 expression is quantified. Does this perturbation result in a significant change in SPINK5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3133,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1423,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and RP11-61E11.1 expression is observed. Does this perturbation lead to a significant difference in RP11-61E11.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and RP11-61E11.1 expression is observed. Does this perturbation lead to a significant difference in RP11-61E11.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and SBF2 expression is quantified. Does this perturbation result in a significant change in SBF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and SBF2 expression is quantified. Does this perturbation result in a significant change in SBF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Determine whether SLC27A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Determine whether SLC27A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of LINC00657. Does this perturbation cause a significant change in LINC00657 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of LINC00657. Does this perturbation cause a significant change in LINC00657 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RNF8. Does perturbing TTI1 lead to a significant change in RNF8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RNF8. Does perturbing TTI1 lead to a significant change in RNF8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of CELF6. Does this perturbation cause a significant change in CELF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of CELF6. Does this perturbation cause a significant change in CELF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of STARD9. Does this perturbation cause a significant change in STARD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of STARD9. Does this perturbation cause a significant change in STARD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2098,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and OPTN expression is measured. Determine whether OPTN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and OPTN expression is measured. Determine whether OPTN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and REST expression is measured. Determine whether REST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and REST expression is measured. Determine whether REST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-227G15.8. Does perturbing TARS lead to a significant change in RP11-227G15.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-227G15.8. Does perturbing TARS lead to a significant change in RP11-227G15.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TRIM24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TRIM24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of MS4A6E. Does perturbing SEC61A1 lead to a significant change in MS4A6E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of MS4A6E. Does perturbing SEC61A1 lead to a significant change in MS4A6E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RSAD2. Does perturbing FECH lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RSAD2. Does perturbing FECH lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of MED13. Does this perturbation cause a significant change in MED13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of MED13. Does this perturbation cause a significant change in MED13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of CLCA1. Does perturbing TELO2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of CLCA1. Does perturbing TELO2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NSD1 expression is quantified. Does this perturbation result in a significant change in NSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NSD1 expression is quantified. Does this perturbation result in a significant change in NSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Determine whether NAV2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Determine whether NAV2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3260,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Does this perturbation cause a significant change in HLA-E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Does this perturbation cause a significant change in HLA-E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Determine whether SERPINH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Determine whether SERPINH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TRIM24 expression is quantified. Does this perturbation result in a significant change in TRIM24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TRIM24 expression is quantified. Does this perturbation result in a significant change in TRIM24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CTD-2521M24.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CTD-2521M24.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2258,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AC015987.1 expression. Decide whether this perturbation leads to a significant alteration in AC015987.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AC015987.1 expression. Decide whether this perturbation leads to a significant alteration in AC015987.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of RSL24D1. Does this perturbation cause a significant change in RSL24D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of RSL24D1. Does this perturbation cause a significant change in RSL24D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3643,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and RP11-3D4.3 expression is observed. Does this perturbation lead to a significant difference in RP11-3D4.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and RP11-3D4.3 expression is observed. Does this perturbation lead to a significant difference in RP11-3D4.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of NINJ2. Does perturbing SLC39A7 lead to a significant change in NINJ2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of NINJ2. Does perturbing SLC39A7 lead to a significant change in NINJ2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in TMOD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in TMOD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of GDF11. Does this perturbation cause a significant change in GDF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of GDF11. Does this perturbation cause a significant change in GDF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PDE9A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PDE9A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2030,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Does this perturbation cause a significant change in RP11-212I21.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Does this perturbation cause a significant change in RP11-212I21.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is measured. Determine whether CTC-308K20.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is measured. Determine whether CTC-308K20.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2200,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Does this perturbation cause a significant change in CST7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Does this perturbation cause a significant change in CST7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-863K10.7 expression is measured. Determine whether RP11-863K10.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-863K10.7 expression is measured. Determine whether RP11-863K10.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of RP11-381O7.3. Does perturbing SEL1L lead to a significant change in RP11-381O7.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of RP11-381O7.3. Does perturbing SEL1L lead to a significant change in RP11-381O7.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1940,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Does this perturbation cause a significant change in GLG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Does this perturbation cause a significant change in GLG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ATP5EP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ATP5EP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ADAMTS10 expression is quantified. Does this perturbation result in a significant change in ADAMTS10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ADAMTS10 expression is quantified. Does this perturbation result in a significant change in ADAMTS10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3780,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of DOCK8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of DOCK8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ZNF341. Does this perturbation cause a significant change in ZNF341 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ZNF341. Does this perturbation cause a significant change in ZNF341 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1943,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GLG1 expression is observed. Does this perturbation lead to a significant difference in GLG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GLG1 expression is observed. Does this perturbation lead to a significant difference in GLG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of PRRC2B. Does perturbing DARS lead to a significant change in PRRC2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of PRRC2B. Does perturbing DARS lead to a significant change in PRRC2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Determine whether KHDC1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Determine whether KHDC1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2750,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Does this perturbation cause a significant change in RP11-685N10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Does this perturbation cause a significant change in RP11-685N10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1890,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Does this perturbation cause a significant change in RP11-434H6.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Does this perturbation cause a significant change in RP11-434H6.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
348,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor MS4A6E expression. Decide whether this perturbation leads to a significant alteration in MS4A6E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor MS4A6E expression. Decide whether this perturbation leads to a significant alteration in MS4A6E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1218,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor JARID2 expression. Decide whether this perturbation leads to a significant alteration in JARID2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor JARID2 expression. Decide whether this perturbation leads to a significant alteration in JARID2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in UBE2V1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in UBE2V1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4658,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KIAA1586 expression. Decide whether this perturbation leads to a significant alteration in KIAA1586 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KIAA1586 expression. Decide whether this perturbation leads to a significant alteration in KIAA1586 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in TMEM87B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in TMEM87B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3038,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-838N2.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-838N2.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-838N2.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-838N2.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of CTD-2001C12.1. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of CTD-2001C12.1. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1173,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
77,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of CEBPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of CEBPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and DST expression is quantified. Does this perturbation result in a significant change in DST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and DST expression is quantified. Does this perturbation result in a significant change in DST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2530,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in PTGS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in PTGS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of SLC26A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of SLC26A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Determine whether MEX3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Determine whether MEX3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HIST1H3D expression is measured. Determine whether HIST1H3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HIST1H3D expression is measured. Determine whether HIST1H3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Determine whether EPB42 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Determine whether EPB42 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1353,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and TAGLN expression is observed. Does this perturbation lead to a significant difference in TAGLN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and TAGLN expression is observed. Does this perturbation lead to a significant difference in TAGLN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TRIM24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TRIM24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4233,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and RP11-666A20.4 expression is observed. Does this perturbation lead to a significant difference in RP11-666A20.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and RP11-666A20.4 expression is observed. Does this perturbation lead to a significant difference in RP11-666A20.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RASGRP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RASGRP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HIST1H1E. Does perturbing IARS2 lead to a significant change in HIST1H1E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HIST1H1E. Does perturbing IARS2 lead to a significant change in HIST1H1E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of STARD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of STARD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of BIRC5. Does perturbing DHDDS lead to a significant change in BIRC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of BIRC5. Does perturbing DHDDS lead to a significant change in BIRC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4698,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ANKRD11 expression. Decide whether this perturbation leads to a significant alteration in ANKRD11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ANKRD11 expression. Decide whether this perturbation leads to a significant alteration in ANKRD11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in RP11-666A20.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in RP11-666A20.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4498,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor SMCO1 expression. Decide whether this perturbation leads to a significant alteration in SMCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor SMCO1 expression. Decide whether this perturbation leads to a significant alteration in SMCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of LRRC4B. Does this perturbation cause a significant change in LRRC4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of LRRC4B. Does this perturbation cause a significant change in LRRC4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3330,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Does this perturbation cause a significant change in AP000688.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Does this perturbation cause a significant change in AP000688.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and NPAT expression is measured. Determine whether NPAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and NPAT expression is measured. Determine whether NPAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is quantified. Does this perturbation result in a significant change in ATP6V1B2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is quantified. Does this perturbation result in a significant change in ATP6V1B2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in NAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in NAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4088,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3428,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1518,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor TMOD3 expression. Decide whether this perturbation leads to a significant alteration in TMOD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor TMOD3 expression. Decide whether this perturbation leads to a significant alteration in TMOD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of FAM114A1. Does perturbing SLMO2 lead to a significant change in FAM114A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of FAM114A1. Does perturbing SLMO2 lead to a significant change in FAM114A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2500,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Does this perturbation cause a significant change in UFD1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Does this perturbation cause a significant change in UFD1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of SEC23IP. Does perturbing TMED10 lead to a significant change in SEC23IP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of SEC23IP. Does perturbing TMED10 lead to a significant change in SEC23IP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and CFH expression is measured. Determine whether CFH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and CFH expression is measured. Determine whether CFH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of CTD-2267D19.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of CTD-2267D19.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of UQCRB. Does this perturbation cause a significant change in UQCRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of UQCRB. Does this perturbation cause a significant change in UQCRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC096559.1 expression is quantified. Does this perturbation result in a significant change in AC096559.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC096559.1 expression is quantified. Does this perturbation result in a significant change in AC096559.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PSMC1. Does this perturbation cause a significant change in PSMC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PSMC1. Does this perturbation cause a significant change in PSMC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of NXF1. Does this perturbation cause a significant change in NXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of NXF1. Does this perturbation cause a significant change in NXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2158,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SNRNP25 expression. Decide whether this perturbation leads to a significant alteration in SNRNP25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SNRNP25 expression. Decide whether this perturbation leads to a significant alteration in SNRNP25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ATF7IP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ATF7IP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of IRF7. Does this perturbation cause a significant change in IRF7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of IRF7. Does this perturbation cause a significant change in IRF7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2343,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and C19orf59 expression is observed. Does this perturbation lead to a significant difference in C19orf59 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and C19orf59 expression is observed. Does this perturbation lead to a significant difference in C19orf59 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1183,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SETD5-AS1 expression is observed. Does this perturbation lead to a significant difference in SETD5-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SETD5-AS1 expression is observed. Does this perturbation lead to a significant difference in SETD5-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4930,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Does this perturbation cause a significant change in ATXN7L3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Does this perturbation cause a significant change in ATXN7L3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in STARD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in STARD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4243,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and LINC01031 expression is observed. Does this perturbation lead to a significant difference in LINC01031 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and LINC01031 expression is observed. Does this perturbation lead to a significant difference in LINC01031 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of MYH7B. Does this perturbation cause a significant change in MYH7B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of MYH7B. Does this perturbation cause a significant change in MYH7B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TTC32. Does this perturbation cause a significant change in TTC32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TTC32. Does this perturbation cause a significant change in TTC32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ATF7IP2 expression is measured. Determine whether ATF7IP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ATF7IP2 expression is measured. Determine whether ATF7IP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Determine whether CMTM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Determine whether CMTM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RSAD2. Does perturbing MRGBP lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RSAD2. Does perturbing MRGBP lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of MYH7B. Does perturbing YIPF5 lead to a significant change in MYH7B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of MYH7B. Does perturbing YIPF5 lead to a significant change in MYH7B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP11-119J18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP11-119J18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IFT27. Does perturbing CHERP lead to a significant change in IFT27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IFT27. Does perturbing CHERP lead to a significant change in IFT27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Determine whether RP11-334C17.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Determine whether RP11-334C17.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4650,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Does this perturbation cause a significant change in KIAA1586 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Does this perturbation cause a significant change in KIAA1586 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PIK3IP1. Does this perturbation cause a significant change in PIK3IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PIK3IP1. Does this perturbation cause a significant change in PIK3IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of ACRV1. Does this perturbation cause a significant change in ACRV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of ACRV1. Does this perturbation cause a significant change in ACRV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of AC012594.1. Does perturbing ATP5B lead to a significant change in AC012594.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of AC012594.1. Does perturbing ATP5B lead to a significant change in AC012594.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PHF19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PHF19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of RP11-90P5.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of RP11-90P5.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
573,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and CTD-2001C12.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2001C12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and CTD-2001C12.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2001C12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
570,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2563,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and SBF2 expression is observed. Does this perturbation lead to a significant difference in SBF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and SBF2 expression is observed. Does this perturbation lead to a significant difference in SBF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3100,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Does this perturbation cause a significant change in PSMD14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Does this perturbation cause a significant change in PSMD14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and MTPN expression is measured. Determine whether MTPN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and MTPN expression is measured. Determine whether MTPN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of TMEM87B. Does perturbing TIMM23 lead to a significant change in TMEM87B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of TMEM87B. Does perturbing TIMM23 lead to a significant change in TMEM87B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CD83. Does perturbing MANF lead to a significant change in CD83 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CD83. Does perturbing MANF lead to a significant change in CD83 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
55,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in C6orf48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in C6orf48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in SLFNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in SLFNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1198,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor RP11-435O5.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-435O5.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor RP11-435O5.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-435O5.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and CENPF expression is quantified. Does this perturbation result in a significant change in CENPF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and CENPF expression is quantified. Does this perturbation result in a significant change in CENPF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PHF19 expression is quantified. Does this perturbation result in a significant change in PHF19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PHF19 expression is quantified. Does this perturbation result in a significant change in PHF19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3818,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor RP11-445H22.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-445H22.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor RP11-445H22.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-445H22.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4478,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor RP11-95O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-95O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor RP11-95O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-95O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of WDR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of WDR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and SLC27A2 expression is quantified. Does this perturbation result in a significant change in SLC27A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and SLC27A2 expression is quantified. Does this perturbation result in a significant change in SLC27A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
163,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RIMS3 expression is observed. Does this perturbation lead to a significant difference in RIMS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RIMS3 expression is observed. Does this perturbation lead to a significant difference in RIMS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of NAV1. Does perturbing PPWD1 lead to a significant change in NAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of NAV1. Does perturbing PPWD1 lead to a significant change in NAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of HLA-AS1. Does perturbing DAD1 lead to a significant change in HLA-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of HLA-AS1. Does perturbing DAD1 lead to a significant change in HLA-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of SPCS2. Does this perturbation cause a significant change in SPCS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of SPCS2. Does this perturbation cause a significant change in SPCS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NOXA1. Does perturbing SAMM50 lead to a significant change in NOXA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NOXA1. Does perturbing SAMM50 lead to a significant change in NOXA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4183,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ANKRD33 expression is observed. Does this perturbation lead to a significant difference in ANKRD33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ANKRD33 expression is observed. Does this perturbation lead to a significant difference in ANKRD33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in CTD-2020K17.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in CTD-2020K17.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NUF2. Does this perturbation cause a significant change in NUF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NUF2. Does this perturbation cause a significant change in NUF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of SAMM50. Does this perturbation cause a significant change in SAMM50 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of SAMM50. Does this perturbation cause a significant change in SAMM50 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2400,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1653,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and EBI3 expression is observed. Does this perturbation lead to a significant difference in EBI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and EBI3 expression is observed. Does this perturbation lead to a significant difference in EBI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4988,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor UHMK1 expression. Decide whether this perturbation leads to a significant alteration in UHMK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor UHMK1 expression. Decide whether this perturbation leads to a significant alteration in UHMK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of GOT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of GOT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4600,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Does this perturbation cause a significant change in STARD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Does this perturbation cause a significant change in STARD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
918,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HIST1H3D expression. Decide whether this perturbation leads to a significant alteration in HIST1H3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HIST1H3D expression. Decide whether this perturbation leads to a significant alteration in HIST1H3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2773,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ABI2 expression is quantified. Does this perturbation result in a significant change in ABI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ABI2 expression is quantified. Does this perturbation result in a significant change in ABI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1548,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor CTD-2267D19.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-2267D19.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor CTD-2267D19.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-2267D19.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Determine whether GNPTG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Determine whether GNPTG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2813,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDKN2C expression is observed. Does this perturbation lead to a significant difference in CDKN2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDKN2C expression is observed. Does this perturbation lead to a significant difference in CDKN2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ZNF341. Does perturbing PTDSS1 lead to a significant change in ZNF341 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ZNF341. Does perturbing PTDSS1 lead to a significant change in ZNF341 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RP11-3D4.3. Does perturbing EIF2S1 lead to a significant change in RP11-3D4.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RP11-3D4.3. Does perturbing EIF2S1 lead to a significant change in RP11-3D4.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4053,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP11-15E18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-15E18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP11-15E18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-15E18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Determine whether RP11-2H8.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Determine whether RP11-2H8.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CHST12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CHST12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
310,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is measured. Determine whether RP11-95O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is measured. Determine whether RP11-95O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2730,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is quantified. Does this perturbation result in a significant change in CTD-2267D19.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is quantified. Does this perturbation result in a significant change in CTD-2267D19.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4888,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor WARS expression. Decide whether this perturbation leads to a significant alteration in WARS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor WARS expression. Decide whether this perturbation leads to a significant alteration in WARS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and AP000688.8 expression is quantified. Does this perturbation result in a significant change in AP000688.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and AP000688.8 expression is quantified. Does this perturbation result in a significant change in AP000688.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RP11-24F11.2. Does perturbing MRGBP lead to a significant change in RP11-24F11.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RP11-24F11.2. Does perturbing MRGBP lead to a significant change in RP11-24F11.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Determine whether C19orf59 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Determine whether C19orf59 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TRPM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TRPM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1750,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2140,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Does this perturbation cause a significant change in NINJ2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Does this perturbation cause a significant change in NINJ2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NSD1. Does perturbing STT3A lead to a significant change in NSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NSD1. Does perturbing STT3A lead to a significant change in NSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
66,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Determine whether RIOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Determine whether RIOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1848,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor OR2T6 expression. Decide whether this perturbation leads to a significant alteration in OR2T6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor OR2T6 expression. Decide whether this perturbation leads to a significant alteration in OR2T6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of NTRK1. Does this perturbation cause a significant change in NTRK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of NTRK1. Does this perturbation cause a significant change in NTRK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CLINT1 expression is measured. Determine whether CLINT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CLINT1 expression is measured. Determine whether CLINT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of RP11-423O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of RP11-423O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ABI2. Does perturbing GNPNAT1 lead to a significant change in ABI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ABI2. Does perturbing GNPNAT1 lead to a significant change in ABI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in CD46 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in CD46 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2723,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and RNF139-AS1 expression is measured. Determine whether RNF139-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and RNF139-AS1 expression is measured. Determine whether RNF139-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of SNHG12. Does perturbing AMIGO3 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of SNHG12. Does perturbing AMIGO3 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SMIM14 expression is quantified. Does this perturbation result in a significant change in SMIM14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SMIM14 expression is quantified. Does this perturbation result in a significant change in SMIM14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1663,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and RP11-247A12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-247A12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and RP11-247A12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-247A12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
108,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor NBEAL2 expression. Decide whether this perturbation leads to a significant alteration in NBEAL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor NBEAL2 expression. Decide whether this perturbation leads to a significant alteration in NBEAL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
12,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
103,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and NBEAL2 expression is observed. Does this perturbation lead to a significant difference in NBEAL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and NBEAL2 expression is observed. Does this perturbation lead to a significant difference in NBEAL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3773,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ZNF341 expression is observed. Does this perturbation lead to a significant difference in ZNF341 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ZNF341 expression is observed. Does this perturbation lead to a significant difference in ZNF341 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4153,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and PDRG1 expression is observed. Does this perturbation lead to a significant difference in PDRG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and PDRG1 expression is observed. Does this perturbation lead to a significant difference in PDRG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3373,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and LIMS1 expression is observed. Does this perturbation lead to a significant difference in LIMS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and LIMS1 expression is observed. Does this perturbation lead to a significant difference in LIMS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EPS15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EPS15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Determine whether MBNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Determine whether MBNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TUBA1C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TUBA1C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in RP11-146D12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in RP11-146D12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3478,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor BACH2 expression. Decide whether this perturbation leads to a significant alteration in BACH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor BACH2 expression. Decide whether this perturbation leads to a significant alteration in BACH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and KCTD19 expression is quantified. Does this perturbation result in a significant change in KCTD19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and KCTD19 expression is quantified. Does this perturbation result in a significant change in KCTD19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1583,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ACRV1. Does perturbing DDOST lead to a significant change in ACRV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ACRV1. Does perturbing DDOST lead to a significant change in ACRV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of STK17B. Does this perturbation cause a significant change in STK17B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of STK17B. Does this perturbation cause a significant change in STK17B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4440,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Does this perturbation cause a significant change in CTBS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Does this perturbation cause a significant change in CTBS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of RILPL2. Does perturbing COPB1 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of RILPL2. Does perturbing COPB1 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3120,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in TIPARP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in TIPARP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4248,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor LINC01031 expression. Decide whether this perturbation leads to a significant alteration in LINC01031 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor LINC01031 expression. Decide whether this perturbation leads to a significant alteration in LINC01031 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of PAK1IP1. Does this perturbation cause a significant change in PAK1IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of PAK1IP1. Does this perturbation cause a significant change in PAK1IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TUBA1C expression is measured. Determine whether TUBA1C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TUBA1C expression is measured. Determine whether TUBA1C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ZNF429. Does perturbing CREB1 lead to a significant change in ZNF429 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ZNF429. Does perturbing CREB1 lead to a significant change in ZNF429 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and CDCA3 expression is quantified. Does this perturbation result in a significant change in CDCA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and CDCA3 expression is quantified. Does this perturbation result in a significant change in CDCA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Determine whether ERP29 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Determine whether ERP29 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2608,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CTCFL expression. Decide whether this perturbation leads to a significant alteration in CTCFL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CTCFL expression. Decide whether this perturbation leads to a significant alteration in CTCFL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of RP11-434H6.6. Does perturbing CAD lead to a significant change in RP11-434H6.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of RP11-434H6.6. Does perturbing CAD lead to a significant change in RP11-434H6.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Determine whether ZEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Determine whether ZEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of DDX6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of DDX6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in RAD51AP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in RAD51AP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3053,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-363D14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-363D14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-363D14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-363D14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
393,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and GDF11 expression is observed. Does this perturbation lead to a significant difference in GDF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and GDF11 expression is observed. Does this perturbation lead to a significant difference in GDF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1120,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Does this perturbation cause a significant change in RP11-640M9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Does this perturbation cause a significant change in RP11-640M9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PAXBP1 expression is measured. Determine whether PAXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PAXBP1 expression is measured. Determine whether PAXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1733,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and USP37 expression is observed. Does this perturbation lead to a significant difference in USP37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and USP37 expression is observed. Does this perturbation lead to a significant difference in USP37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of TAGLN. Does perturbing STT3A lead to a significant change in TAGLN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of TAGLN. Does perturbing STT3A lead to a significant change in TAGLN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of TMOD3. Does this perturbation cause a significant change in TMOD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of TMOD3. Does this perturbation cause a significant change in TMOD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of AC104532.4. Does this perturbation cause a significant change in AC104532.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of AC104532.4. Does this perturbation cause a significant change in AC104532.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3528,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TSPAN33 expression. Decide whether this perturbation leads to a significant alteration in TSPAN33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TSPAN33 expression. Decide whether this perturbation leads to a significant alteration in TSPAN33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and SOBP expression is quantified. Does this perturbation result in a significant change in SOBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and SOBP expression is quantified. Does this perturbation result in a significant change in SOBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
403,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and RP11-90P5.2 expression is observed. Does this perturbation lead to a significant difference in RP11-90P5.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and RP11-90P5.2 expression is observed. Does this perturbation lead to a significant difference in RP11-90P5.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and DNASE2 expression is quantified. Does this perturbation result in a significant change in DNASE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and DNASE2 expression is quantified. Does this perturbation result in a significant change in DNASE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ZFP36L2. Does this perturbation cause a significant change in ZFP36L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ZFP36L2. Does this perturbation cause a significant change in ZFP36L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
960,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Does this perturbation cause a significant change in ZEB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Does this perturbation cause a significant change in ZEB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CHST12. Does perturbing KCTD16 lead to a significant change in CHST12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CHST12. Does perturbing KCTD16 lead to a significant change in CHST12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3410,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Does this perturbation cause a significant change in NOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Does this perturbation cause a significant change in NOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2433,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP13-216E22.4 expression is observed. Does this perturbation lead to a significant difference in RP13-216E22.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP13-216E22.4 expression is observed. Does this perturbation lead to a significant difference in RP13-216E22.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of RP11-445H22.3. Does perturbing HYOU1 lead to a significant change in RP11-445H22.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of RP11-445H22.3. Does perturbing HYOU1 lead to a significant change in RP11-445H22.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of CTD-2587M2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of CTD-2587M2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2883,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-499F3.2 expression is observed. Does this perturbation lead to a significant difference in RP11-499F3.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-499F3.2 expression is observed. Does this perturbation lead to a significant difference in RP11-499F3.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of RP11-181G12.2. Does perturbing SRPRB lead to a significant change in RP11-181G12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of RP11-181G12.2. Does perturbing SRPRB lead to a significant change in RP11-181G12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4298,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Determine whether CTD-2020K17.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Determine whether CTD-2020K17.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MT2A expression is quantified. Does this perturbation result in a significant change in MT2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MT2A expression is quantified. Does this perturbation result in a significant change in MT2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in BOLA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in BOLA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of TSC22D4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of TSC22D4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of CCRL2. Does perturbing SRP68 lead to a significant change in CCRL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of CCRL2. Does perturbing SRP68 lead to a significant change in CCRL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Determine whether ESCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Determine whether ESCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and WDR72 expression is measured. Determine whether WDR72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and WDR72 expression is measured. Determine whether WDR72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NSD1. Does this perturbation cause a significant change in NSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NSD1. Does this perturbation cause a significant change in NSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
828,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor TMEM87B expression. Decide whether this perturbation leads to a significant alteration in TMEM87B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor TMEM87B expression. Decide whether this perturbation leads to a significant alteration in TMEM87B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Determine whether SNHG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Determine whether SNHG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MLEC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MLEC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1238,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor SRP72 expression. Decide whether this perturbation leads to a significant alteration in SRP72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor SRP72 expression. Decide whether this perturbation leads to a significant alteration in SRP72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of LTBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of LTBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in HERPUD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in HERPUD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and SAMM50 expression is measured. Determine whether SAMM50 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and SAMM50 expression is measured. Determine whether SAMM50 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-328J2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-328J2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Determine whether AC008074.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Determine whether AC008074.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and AKAP11 expression is measured. Determine whether AKAP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and AKAP11 expression is measured. Determine whether AKAP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1833,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ATP2A3 expression is observed. Does this perturbation lead to a significant difference in ATP2A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ATP2A3 expression is observed. Does this perturbation lead to a significant difference in ATP2A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of H3F3B. Does perturbing TELO2 lead to a significant change in H3F3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of H3F3B. Does perturbing TELO2 lead to a significant change in H3F3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in C12orf44 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in C12orf44 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2348,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor C19orf59 expression. Decide whether this perturbation leads to a significant alteration in C19orf59 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor C19orf59 expression. Decide whether this perturbation leads to a significant alteration in C19orf59 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1250,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Does this perturbation cause a significant change in IL8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Does this perturbation cause a significant change in IL8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1908,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC008074.3 expression. Decide whether this perturbation leads to a significant alteration in AC008074.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC008074.3 expression. Decide whether this perturbation leads to a significant alteration in AC008074.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and DOCK11 expression is quantified. Does this perturbation result in a significant change in DOCK11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and DOCK11 expression is quantified. Does this perturbation result in a significant change in DOCK11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ZEB2 expression is measured. Determine whether ZEB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ZEB2 expression is measured. Determine whether ZEB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and IRF7 expression is quantified. Does this perturbation result in a significant change in IRF7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and IRF7 expression is quantified. Does this perturbation result in a significant change in IRF7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of RPL39 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of RPL39 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
553,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and OPTN expression is observed. Does this perturbation lead to a significant difference in OPTN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and OPTN expression is observed. Does this perturbation lead to a significant difference in OPTN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and TAGLN expression is measured. Determine whether TAGLN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and TAGLN expression is measured. Determine whether TAGLN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ATF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ATF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of S100A11. Does perturbing HSPA5 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of S100A11. Does perturbing HSPA5 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ATXN7L3B. Does this perturbation cause a significant change in ATXN7L3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ATXN7L3B. Does this perturbation cause a significant change in ATXN7L3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3093,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and GNPTG expression is observed. Does this perturbation lead to a significant difference in GNPTG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and GNPTG expression is observed. Does this perturbation lead to a significant difference in GNPTG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
618,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor HP1BP3 expression. Decide whether this perturbation leads to a significant alteration in HP1BP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor HP1BP3 expression. Decide whether this perturbation leads to a significant alteration in HP1BP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2408,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of SPCS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of SPCS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CTCFL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CTCFL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Determine whether RASGRP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Determine whether RASGRP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and PARP11 expression is measured. Determine whether PARP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and PARP11 expression is measured. Determine whether PARP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and KLF3 expression is measured. Determine whether KLF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and KLF3 expression is measured. Determine whether KLF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
198,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PDE9A expression. Decide whether this perturbation leads to a significant alteration in PDE9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PDE9A expression. Decide whether this perturbation leads to a significant alteration in PDE9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3748,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA0922 expression. Decide whether this perturbation leads to a significant alteration in KIAA0922 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA0922 expression. Decide whether this perturbation leads to a significant alteration in KIAA0922 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2090,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2283,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2110,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4448,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CTBS expression. Decide whether this perturbation leads to a significant alteration in CTBS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CTBS expression. Decide whether this perturbation leads to a significant alteration in CTBS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of GCKR. Does perturbing AARS lead to a significant change in GCKR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of GCKR. Does perturbing AARS lead to a significant change in GCKR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RIMS3. Does perturbing BHLHE40 lead to a significant change in RIMS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RIMS3. Does perturbing BHLHE40 lead to a significant change in RIMS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
560,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Does this perturbation cause a significant change in IL32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Does this perturbation cause a significant change in IL32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NOXA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NOXA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Determine whether RP11-227G15.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Determine whether RP11-227G15.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of RP11-430H10.1. Does this perturbation cause a significant change in RP11-430H10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of RP11-430H10.1. Does this perturbation cause a significant change in RP11-430H10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ATAD2B expression is quantified. Does this perturbation result in a significant change in ATAD2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ATAD2B expression is quantified. Does this perturbation result in a significant change in ATAD2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of TSNAXIP1. Does this perturbation cause a significant change in TSNAXIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of TSNAXIP1. Does this perturbation cause a significant change in TSNAXIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of FGF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of FGF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EGLN3 expression is quantified. Does this perturbation result in a significant change in EGLN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EGLN3 expression is quantified. Does this perturbation result in a significant change in EGLN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
21,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of RUNX1. Does perturbing CREB1 lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of RUNX1. Does perturbing CREB1 lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and LINC00657 expression is measured. Determine whether LINC00657 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and LINC00657 expression is measured. Determine whether LINC00657 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1030,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Does this perturbation cause a significant change in TLN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Does this perturbation cause a significant change in TLN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PDE3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PDE3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of LINC00862 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of LINC00862 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and MEX3B expression is quantified. Does this perturbation result in a significant change in MEX3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and MEX3B expression is quantified. Does this perturbation result in a significant change in MEX3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and TAP1 expression is quantified. Does this perturbation result in a significant change in TAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and TAP1 expression is quantified. Does this perturbation result in a significant change in TAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2840,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4808,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EIF3A expression. Decide whether this perturbation leads to a significant alteration in EIF3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EIF3A expression. Decide whether this perturbation leads to a significant alteration in EIF3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1553,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and RP11-381O7.3 expression is observed. Does this perturbation lead to a significant difference in RP11-381O7.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and RP11-381O7.3 expression is observed. Does this perturbation lead to a significant difference in RP11-381O7.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ERP29. Does this perturbation cause a significant change in ERP29 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ERP29. Does this perturbation cause a significant change in ERP29 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2148,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor NINJ2 expression. Decide whether this perturbation leads to a significant alteration in NINJ2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor NINJ2 expression. Decide whether this perturbation leads to a significant alteration in NINJ2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RP11-157D23.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RP11-157D23.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4370,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Does this perturbation cause a significant change in RP11-181G12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Does this perturbation cause a significant change in RP11-181G12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HRK. Does this perturbation cause a significant change in HRK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HRK. Does this perturbation cause a significant change in HRK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ZP3. Does perturbing FARSB lead to a significant change in ZP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ZP3. Does perturbing FARSB lead to a significant change in ZP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Determine whether C12orf23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Determine whether C12orf23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in USP34 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in USP34 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and TSC22D4 expression is quantified. Does this perturbation result in a significant change in TSC22D4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and TSC22D4 expression is quantified. Does this perturbation result in a significant change in TSC22D4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
508,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PTPN11 expression. Decide whether this perturbation leads to a significant alteration in PTPN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PTPN11 expression. Decide whether this perturbation leads to a significant alteration in PTPN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4803,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EIF3A expression is observed. Does this perturbation lead to a significant difference in EIF3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EIF3A expression is observed. Does this perturbation lead to a significant difference in EIF3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of SPINK5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of SPINK5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of S100A11. Does perturbing EIF2B3 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of S100A11. Does perturbing EIF2B3 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CD9 expression is quantified. Does this perturbation result in a significant change in CD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CD9 expression is quantified. Does this perturbation result in a significant change in CD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4563,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and WDR3 expression is observed. Does this perturbation lead to a significant difference in WDR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and WDR3 expression is observed. Does this perturbation lead to a significant difference in WDR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of CTSF. Does this perturbation cause a significant change in CTSF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of CTSF. Does this perturbation cause a significant change in CTSF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is measured. Determine whether RP11-423O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is measured. Determine whether RP11-423O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3128,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Determine whether SMCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Determine whether SMCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP11-119J18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP11-119J18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
238,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PTPRC expression. Decide whether this perturbation leads to a significant alteration in PTPRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PTPRC expression. Decide whether this perturbation leads to a significant alteration in PTPRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of FCGRT. Does perturbing SCYL1 lead to a significant change in FCGRT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of FCGRT. Does perturbing SCYL1 lead to a significant change in FCGRT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Determine whether CD58 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Determine whether CD58 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Determine whether RP11-157D23.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Determine whether RP11-157D23.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4838,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor RP11-390B4.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-390B4.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor RP11-390B4.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-390B4.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of RP11-381O7.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of RP11-381O7.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and RGS3 expression is quantified. Does this perturbation result in a significant change in RGS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and RGS3 expression is quantified. Does this perturbation result in a significant change in RGS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RASGRP2. Does perturbing AARS lead to a significant change in RASGRP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RASGRP2. Does perturbing AARS lead to a significant change in RASGRP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1898,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor RP11-434H6.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-434H6.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor RP11-434H6.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-434H6.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of DNASE2. Does perturbing ATP5B lead to a significant change in DNASE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of DNASE2. Does perturbing ATP5B lead to a significant change in DNASE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Determine whether SERPING1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Determine whether SERPING1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in RP11-81A22.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in RP11-81A22.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is measured. Determine whether RP11-132A1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is measured. Determine whether RP11-132A1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in TTC18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in TTC18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of TMEM87B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of TMEM87B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3360,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1953,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4400,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2918,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AFF1 expression. Decide whether this perturbation leads to a significant alteration in AFF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AFF1 expression. Decide whether this perturbation leads to a significant alteration in AFF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ZP3. Does this perturbation cause a significant change in ZP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ZP3. Does this perturbation cause a significant change in ZP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and LINC00862 expression is quantified. Does this perturbation result in a significant change in LINC00862 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and LINC00862 expression is quantified. Does this perturbation result in a significant change in LINC00862 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of EIF4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of EIF4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
453,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and SLFNL1 expression is observed. Does this perturbation lead to a significant difference in SLFNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and SLFNL1 expression is observed. Does this perturbation lead to a significant difference in SLFNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of UBE2V1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of UBE2V1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
690,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Does this perturbation cause a significant change in SPCS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Does this perturbation cause a significant change in SPCS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-863K10.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-863K10.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in NPAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in NPAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HRK expression is quantified. Does this perturbation result in a significant change in HRK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HRK expression is quantified. Does this perturbation result in a significant change in HRK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of KCNH7. Does perturbing MTHFD1 lead to a significant change in KCNH7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of KCNH7. Does perturbing MTHFD1 lead to a significant change in KCNH7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1918,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor CTD-2587M2.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2587M2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor CTD-2587M2.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2587M2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4470,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Does this perturbation cause a significant change in RP11-95O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Does this perturbation cause a significant change in RP11-95O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1933,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2188,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ATAD2B. Does this perturbation cause a significant change in ATAD2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ATAD2B. Does this perturbation cause a significant change in ATAD2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of APOBEC3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of APOBEC3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1673,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and AC012594.1 expression is observed. Does this perturbation lead to a significant difference in AC012594.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and AC012594.1 expression is observed. Does this perturbation lead to a significant difference in AC012594.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ZFP36L2 expression is measured. Determine whether ZFP36L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ZFP36L2 expression is measured. Determine whether ZFP36L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ZP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ZP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2028,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor ABI2 expression. Decide whether this perturbation leads to a significant alteration in ABI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor ABI2 expression. Decide whether this perturbation leads to a significant alteration in ABI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4758,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
463,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ERV3-1 expression is observed. Does this perturbation lead to a significant difference in ERV3-1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ERV3-1 expression is observed. Does this perturbation lead to a significant difference in ERV3-1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2468,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor NUFIP2 expression. Decide whether this perturbation leads to a significant alteration in NUFIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor NUFIP2 expression. Decide whether this perturbation leads to a significant alteration in NUFIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of SKIL. Does this perturbation cause a significant change in SKIL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of SKIL. Does this perturbation cause a significant change in SKIL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and MBNL1 expression is quantified. Does this perturbation result in a significant change in MBNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and MBNL1 expression is quantified. Does this perturbation result in a significant change in MBNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SP100 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SP100 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2103,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PTAR1 expression is observed. Does this perturbation lead to a significant difference in PTAR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PTAR1 expression is observed. Does this perturbation lead to a significant difference in PTAR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2353,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and IL13RA1 expression is observed. Does this perturbation lead to a significant difference in IL13RA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and IL13RA1 expression is observed. Does this perturbation lead to a significant difference in IL13RA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of SLC27A2. Does this perturbation cause a significant change in SLC27A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of SLC27A2. Does this perturbation cause a significant change in SLC27A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of PIK3R3. Does this perturbation cause a significant change in PIK3R3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of PIK3R3. Does this perturbation cause a significant change in PIK3R3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5120,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Does this perturbation cause a significant change in CDT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Does this perturbation cause a significant change in CDT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1670,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Does this perturbation cause a significant change in AC012594.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Does this perturbation cause a significant change in AC012594.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
958,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HERC2 expression. Decide whether this perturbation leads to a significant alteration in HERC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HERC2 expression. Decide whether this perturbation leads to a significant alteration in HERC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in KCNH7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in KCNH7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of LINC00862. Does perturbing COPZ1 lead to a significant change in LINC00862 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of LINC00862. Does perturbing COPZ1 lead to a significant change in LINC00862 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2940,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Does this perturbation cause a significant change in SKIL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Does this perturbation cause a significant change in SKIL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and SMCO1 expression is quantified. Does this perturbation result in a significant change in SMCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and SMCO1 expression is quantified. Does this perturbation result in a significant change in SMCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2573,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ACE expression is observed. Does this perturbation lead to a significant difference in ACE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ACE expression is observed. Does this perturbation lead to a significant difference in ACE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Determine whether OPTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Determine whether OPTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4003,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of SOBP. Does this perturbation cause a significant change in SOBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of SOBP. Does this perturbation cause a significant change in SOBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in MORC2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in MORC2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Determine whether LINC01137 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Determine whether LINC01137 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Determine whether NFAT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Determine whether NFAT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and LRRC4B expression is quantified. Does this perturbation result in a significant change in LRRC4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and LRRC4B expression is quantified. Does this perturbation result in a significant change in LRRC4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2133,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SLBP expression is observed. Does this perturbation lead to a significant difference in SLBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SLBP expression is observed. Does this perturbation lead to a significant difference in SLBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CCDC69 expression is measured. Determine whether CCDC69 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CCDC69 expression is measured. Determine whether CCDC69 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of C19orf59. Does this perturbation cause a significant change in C19orf59 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of C19orf59. Does this perturbation cause a significant change in C19orf59 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2653,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IFNGR1 expression is observed. Does this perturbation lead to a significant difference in IFNGR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IFNGR1 expression is observed. Does this perturbation lead to a significant difference in IFNGR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in DDX3X expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in DDX3X expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2908,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor VAMP2 expression. Decide whether this perturbation leads to a significant alteration in VAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor VAMP2 expression. Decide whether this perturbation leads to a significant alteration in VAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ATP11B. Does this perturbation cause a significant change in ATP11B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ATP11B. Does this perturbation cause a significant change in ATP11B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Determine whether PKDCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Determine whether PKDCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
24,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of RP11-3D4.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of RP11-3D4.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1023,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HIST1H1E expression is observed. Does this perturbation lead to a significant difference in HIST1H1E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HIST1H1E expression is observed. Does this perturbation lead to a significant difference in HIST1H1E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4790,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Does this perturbation cause a significant change in ANPEP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Does this perturbation cause a significant change in ANPEP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3138,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4850,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Does this perturbation cause a significant change in STK17B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Does this perturbation cause a significant change in STK17B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1788,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor KCNH7 expression. Decide whether this perturbation leads to a significant alteration in KCNH7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor KCNH7 expression. Decide whether this perturbation leads to a significant alteration in KCNH7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
79,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and CEBPG expression is measured. Determine whether CEBPG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and CEBPG expression is measured. Determine whether CEBPG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2738,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
643,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and KANSL1L expression is observed. Does this perturbation lead to a significant difference in KANSL1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and KANSL1L expression is observed. Does this perturbation lead to a significant difference in KANSL1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of USP37. Does this perturbation cause a significant change in USP37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of USP37. Does this perturbation cause a significant change in USP37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Determine whether MARCH8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Determine whether MARCH8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of MED13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of MED13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of TFPI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of TFPI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is quantified. Does this perturbation result in a significant change in RP11-242O24.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is quantified. Does this perturbation result in a significant change in RP11-242O24.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CTCFL. Does this perturbation cause a significant change in CTCFL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CTCFL. Does this perturbation cause a significant change in CTCFL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of RP11-138C9.1. Does this perturbation cause a significant change in RP11-138C9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of RP11-138C9.1. Does this perturbation cause a significant change in RP11-138C9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Determine whether EBI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Determine whether EBI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-227G15.8. Does this perturbation cause a significant change in RP11-227G15.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-227G15.8. Does this perturbation cause a significant change in RP11-227G15.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3843,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TRPM4 expression is observed. Does this perturbation lead to a significant difference in TRPM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TRPM4 expression is observed. Does this perturbation lead to a significant difference in TRPM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of P4HB. Does perturbing COPZ1 lead to a significant change in P4HB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of P4HB. Does perturbing COPZ1 lead to a significant change in P4HB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2983,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and AC104532.4 expression is observed. Does this perturbation lead to a significant difference in AC104532.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and AC104532.4 expression is observed. Does this perturbation lead to a significant difference in AC104532.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and PIK3R3 expression is quantified. Does this perturbation result in a significant change in PIK3R3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and PIK3R3 expression is quantified. Does this perturbation result in a significant change in PIK3R3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ZCCHC11 expression is quantified. Does this perturbation result in a significant change in ZCCHC11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ZCCHC11 expression is quantified. Does this perturbation result in a significant change in ZCCHC11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
710,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Does this perturbation cause a significant change in FAM114A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Does this perturbation cause a significant change in FAM114A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of HIST1H2AC. Does perturbing EIF2B2 lead to a significant change in HIST1H2AC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of HIST1H2AC. Does perturbing EIF2B2 lead to a significant change in HIST1H2AC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of C3AR1. Does this perturbation cause a significant change in C3AR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of C3AR1. Does this perturbation cause a significant change in C3AR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Determine whether AC007038.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Determine whether AC007038.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and CTD-2587M2.1 expression is quantified. Does this perturbation result in a significant change in CTD-2587M2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and CTD-2587M2.1 expression is quantified. Does this perturbation result in a significant change in CTD-2587M2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Determine whether RP11-15E18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Determine whether RP11-15E18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of RP11-146D12.2. Does perturbing SRPR lead to a significant change in RP11-146D12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of RP11-146D12.2. Does perturbing SRPR lead to a significant change in RP11-146D12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SLC37A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SLC37A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in MED13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in MED13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4928,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of HM13. Does perturbing DHDDS lead to a significant change in HM13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of HM13. Does perturbing DHDDS lead to a significant change in HM13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2768,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDK13 expression. Decide whether this perturbation leads to a significant alteration in CDK13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDK13 expression. Decide whether this perturbation leads to a significant alteration in CDK13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3908,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of PSORS1C1. Does this perturbation cause a significant change in PSORS1C1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of PSORS1C1. Does this perturbation cause a significant change in PSORS1C1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ARHGAP30. Does perturbing MRGBP lead to a significant change in ARHGAP30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ARHGAP30. Does perturbing MRGBP lead to a significant change in ARHGAP30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1740,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Does this perturbation cause a significant change in RPL39 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Does this perturbation cause a significant change in RPL39 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RDH10 expression is quantified. Does this perturbation result in a significant change in RDH10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RDH10 expression is quantified. Does this perturbation result in a significant change in RDH10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
128,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of CASP8. Does this perturbation cause a significant change in CASP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of CASP8. Does this perturbation cause a significant change in CASP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2948,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor SKIL expression. Decide whether this perturbation leads to a significant alteration in SKIL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor SKIL expression. Decide whether this perturbation leads to a significant alteration in SKIL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Determine whether SLC26A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Determine whether SLC26A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Determine whether HOTAIRM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Determine whether HOTAIRM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1433,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and MARCH8 expression is observed. Does this perturbation lead to a significant difference in MARCH8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and MARCH8 expression is observed. Does this perturbation lead to a significant difference in MARCH8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
740,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Does this perturbation cause a significant change in ANXA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Does this perturbation cause a significant change in ANXA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1938,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ROBO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ROBO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3468,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CHST12 expression. Decide whether this perturbation leads to a significant alteration in CHST12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CHST12 expression. Decide whether this perturbation leads to a significant alteration in CHST12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2248,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AMOTL1 expression. Decide whether this perturbation leads to a significant alteration in AMOTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AMOTL1 expression. Decide whether this perturbation leads to a significant alteration in AMOTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of RAD51AP1. Does this perturbation cause a significant change in RAD51AP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of RAD51AP1. Does this perturbation cause a significant change in RAD51AP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Determine whether PDE4D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Determine whether PDE4D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ZNF280B. Does perturbing QARS lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ZNF280B. Does perturbing QARS lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1318,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Determine whether ATP11B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Determine whether ATP11B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ASPM expression is measured. Determine whether ASPM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ASPM expression is measured. Determine whether ASPM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
268,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DOK3 expression. Decide whether this perturbation leads to a significant alteration in DOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DOK3 expression. Decide whether this perturbation leads to a significant alteration in DOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-863K10.7. Does this perturbation cause a significant change in RP11-863K10.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-863K10.7. Does this perturbation cause a significant change in RP11-863K10.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and HLTF expression is measured. Determine whether HLTF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and HLTF expression is measured. Determine whether HLTF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP5. Does perturbing KCTD16 lead to a significant change in ARHGAP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP5. Does perturbing KCTD16 lead to a significant change in ARHGAP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1808,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor LTBP1 expression. Decide whether this perturbation leads to a significant alteration in LTBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor LTBP1 expression. Decide whether this perturbation leads to a significant alteration in LTBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
858,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ATF6 expression. Decide whether this perturbation leads to a significant alteration in ATF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ATF6 expression. Decide whether this perturbation leads to a significant alteration in ATF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and LBX1 expression is quantified. Does this perturbation result in a significant change in LBX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and LBX1 expression is quantified. Does this perturbation result in a significant change in LBX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and RTN2 expression is measured. Determine whether RTN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and RTN2 expression is measured. Determine whether RTN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4250,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Does this perturbation cause a significant change in PAK1IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Does this perturbation cause a significant change in PAK1IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-65L19.4. Does this perturbation cause a significant change in RP11-65L19.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-65L19.4. Does this perturbation cause a significant change in RP11-65L19.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Determine whether RPL39 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Determine whether RPL39 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Determine whether SERPINF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Determine whether SERPINF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2690,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Does this perturbation cause a significant change in CD83 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Does this perturbation cause a significant change in CD83 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of MTPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of MTPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and AC079466.1 expression is measured. Determine whether AC079466.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and AC079466.1 expression is measured. Determine whether AC079466.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in GPRC5C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in GPRC5C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4598,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor LINC00862 expression. Decide whether this perturbation leads to a significant alteration in LINC00862 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor LINC00862 expression. Decide whether this perturbation leads to a significant alteration in LINC00862 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and APOL4 expression is quantified. Does this perturbation result in a significant change in APOL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and APOL4 expression is quantified. Does this perturbation result in a significant change in APOL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in WARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in WARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of RP11-573D15.9. Does perturbing QARS lead to a significant change in RP11-573D15.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of RP11-573D15.9. Does perturbing QARS lead to a significant change in RP11-573D15.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Determine whether TRIM24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Determine whether TRIM24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of SEC23IP. Does this perturbation cause a significant change in SEC23IP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of SEC23IP. Does this perturbation cause a significant change in SEC23IP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ACE. Does this perturbation cause a significant change in ACE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ACE. Does this perturbation cause a significant change in ACE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
0,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Does this perturbation cause a significant change in ZNF429 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Does this perturbation cause a significant change in ZNF429 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in SEPT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in SEPT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3873,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and C9orf64 expression is observed. Does this perturbation lead to a significant difference in C9orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and C9orf64 expression is observed. Does this perturbation lead to a significant difference in C9orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of MARCH8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of MARCH8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SMIM14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SMIM14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4958,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor PLB1 expression. Decide whether this perturbation leads to a significant alteration in PLB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor PLB1 expression. Decide whether this perturbation leads to a significant alteration in PLB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of APOL4. Does perturbing AMIGO3 lead to a significant change in APOL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of APOL4. Does perturbing AMIGO3 lead to a significant change in APOL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CDT1. Does perturbing SPCS2 lead to a significant change in CDT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CDT1. Does perturbing SPCS2 lead to a significant change in CDT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2078,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of CTD-2587M2.1. Does perturbing CAD lead to a significant change in CTD-2587M2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of CTD-2587M2.1. Does perturbing CAD lead to a significant change in CTD-2587M2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1608,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ATP6V1B2 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1B2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ATP6V1B2 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1B2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
713,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and FAM114A1 expression is observed. Does this perturbation lead to a significant difference in FAM114A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and FAM114A1 expression is observed. Does this perturbation lead to a significant difference in FAM114A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ATP6V1B2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ATP6V1B2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1508,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CDT1. Does this perturbation cause a significant change in CDT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CDT1. Does this perturbation cause a significant change in CDT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ROCK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ROCK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4363,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and USP34 expression is observed. Does this perturbation lead to a significant difference in USP34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and USP34 expression is observed. Does this perturbation lead to a significant difference in USP34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of AC005540.3. Does this perturbation cause a significant change in AC005540.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of AC005540.3. Does this perturbation cause a significant change in AC005540.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
41,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of LPAR5. Does perturbing CREB1 lead to a significant change in LPAR5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of LPAR5. Does perturbing CREB1 lead to a significant change in LPAR5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3840,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Does this perturbation cause a significant change in TRPM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Does this perturbation cause a significant change in TRPM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2068,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor RTN2 expression. Decide whether this perturbation leads to a significant alteration in RTN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor RTN2 expression. Decide whether this perturbation leads to a significant alteration in RTN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of WDR72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of WDR72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1438,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor MARCH8 expression. Decide whether this perturbation leads to a significant alteration in MARCH8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor MARCH8 expression. Decide whether this perturbation leads to a significant alteration in MARCH8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of CTD-2267D19.3. Does perturbing SEL1L lead to a significant change in CTD-2267D19.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of CTD-2267D19.3. Does perturbing SEL1L lead to a significant change in CTD-2267D19.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1068,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor KHDC1L expression. Decide whether this perturbation leads to a significant alteration in KHDC1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor KHDC1L expression. Decide whether this perturbation leads to a significant alteration in KHDC1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of RP11-132A1.4. Does this perturbation cause a significant change in RP11-132A1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of RP11-132A1.4. Does this perturbation cause a significant change in RP11-132A1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1598,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor LBX1 expression. Decide whether this perturbation leads to a significant alteration in LBX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor LBX1 expression. Decide whether this perturbation leads to a significant alteration in LBX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1188,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SETD5-AS1 expression. Decide whether this perturbation leads to a significant alteration in SETD5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SETD5-AS1 expression. Decide whether this perturbation leads to a significant alteration in SETD5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1578,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2828,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PSMC1 expression. Decide whether this perturbation leads to a significant alteration in PSMC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PSMC1 expression. Decide whether this perturbation leads to a significant alteration in PSMC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and FAM212A expression is measured. Determine whether FAM212A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and FAM212A expression is measured. Determine whether FAM212A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3088,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor TROAP expression. Decide whether this perturbation leads to a significant alteration in TROAP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor TROAP expression. Decide whether this perturbation leads to a significant alteration in TROAP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of AKAP11. Does this perturbation cause a significant change in AKAP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of AKAP11. Does this perturbation cause a significant change in AKAP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and POLR2J3 expression is measured. Determine whether POLR2J3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and POLR2J3 expression is measured. Determine whether POLR2J3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SMIM14. Does this perturbation cause a significant change in SMIM14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SMIM14. Does this perturbation cause a significant change in SMIM14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1080,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Does this perturbation cause a significant change in DDX3X expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Does this perturbation cause a significant change in DDX3X expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of C9orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of C9orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in SNHG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in SNHG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Determine whether OBSCN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Determine whether OBSCN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ACE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ACE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4708,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3808,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Determine whether PHF19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Determine whether PHF19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ZEB2. Does this perturbation cause a significant change in ZEB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ZEB2. Does this perturbation cause a significant change in ZEB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DOK3. Does perturbing OST4 lead to a significant change in DOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DOK3. Does perturbing OST4 lead to a significant change in DOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of C3AR1. Does perturbing SRP72 lead to a significant change in C3AR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of C3AR1. Does perturbing SRP72 lead to a significant change in C3AR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Determine whether TOB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Determine whether TOB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of RP11-61E11.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of RP11-61E11.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Determine whether OXLD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Determine whether OXLD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2550,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Does this perturbation cause a significant change in MORC2-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Does this perturbation cause a significant change in MORC2-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of CRNDE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of CRNDE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of LRRC4B. Does perturbing DERL2 lead to a significant change in LRRC4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of LRRC4B. Does perturbing DERL2 lead to a significant change in LRRC4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1793,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and PKDCC expression is observed. Does this perturbation lead to a significant difference in PKDCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and PKDCC expression is observed. Does this perturbation lead to a significant difference in PKDCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in SDF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in SDF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and H3F3B expression is measured. Determine whether H3F3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and H3F3B expression is measured. Determine whether H3F3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Determine whether RP11-322J23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Determine whether RP11-322J23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and RGS3 expression is measured. Determine whether RGS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and RGS3 expression is measured. Determine whether RGS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in LINC00938 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in LINC00938 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CST7 expression is quantified. Does this perturbation result in a significant change in CST7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CST7 expression is quantified. Does this perturbation result in a significant change in CST7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Determine whether H3F3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Determine whether H3F3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ACSM3. Does perturbing DERL2 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ACSM3. Does perturbing DERL2 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Determine whether ATP2A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Determine whether ATP2A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and RPL39 expression is quantified. Does this perturbation result in a significant change in RPL39 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and RPL39 expression is quantified. Does this perturbation result in a significant change in RPL39 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4920,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ZFHX3. Does perturbing AARS lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ZFHX3. Does perturbing AARS lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Determine whether UHRF1BP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Determine whether UHRF1BP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3268,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor HLA-E expression. Decide whether this perturbation leads to a significant alteration in HLA-E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor HLA-E expression. Decide whether this perturbation leads to a significant alteration in HLA-E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of RHCE. Does perturbing SCYL1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of RHCE. Does perturbing SCYL1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2728,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5088,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor GPR146 expression. Decide whether this perturbation leads to a significant alteration in GPR146 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor GPR146 expression. Decide whether this perturbation leads to a significant alteration in GPR146 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of APOL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of APOL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
73,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and CEBPG expression is observed. Does this perturbation lead to a significant difference in CEBPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and CEBPG expression is observed. Does this perturbation lead to a significant difference in CEBPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of RP11-254F7.4. Does this perturbation cause a significant change in RP11-254F7.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of RP11-254F7.4. Does this perturbation cause a significant change in RP11-254F7.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Determine whether CTNNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Determine whether CTNNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3323,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and NPAT expression is observed. Does this perturbation lead to a significant difference in NPAT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and NPAT expression is observed. Does this perturbation lead to a significant difference in NPAT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CCDC69 expression is quantified. Does this perturbation result in a significant change in CCDC69 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CCDC69 expression is quantified. Does this perturbation result in a significant change in CCDC69 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ZP3 expression is measured. Determine whether ZP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ZP3 expression is measured. Determine whether ZP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4228,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IFT27 expression. Decide whether this perturbation leads to a significant alteration in IFT27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IFT27 expression. Decide whether this perturbation leads to a significant alteration in IFT27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4023,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and PIK3R3 expression is observed. Does this perturbation lead to a significant difference in PIK3R3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and PIK3R3 expression is observed. Does this perturbation lead to a significant difference in PIK3R3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Determine whether ATF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Determine whether ATF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ANXA4. Does perturbing DAD1 lead to a significant change in ANXA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ANXA4. Does perturbing DAD1 lead to a significant change in ANXA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is quantified. Does this perturbation result in a significant change in RP3-465N24.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is quantified. Does this perturbation result in a significant change in RP3-465N24.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in KCNE3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in KCNE3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TRIM24. Does this perturbation cause a significant change in TRIM24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TRIM24. Does this perturbation cause a significant change in TRIM24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4218,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor CD46 expression. Decide whether this perturbation leads to a significant alteration in CD46 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor CD46 expression. Decide whether this perturbation leads to a significant alteration in CD46 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of APOBEC3D. Does perturbing SRP68 lead to a significant change in APOBEC3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of APOBEC3D. Does perturbing SRP68 lead to a significant change in APOBEC3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
933,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-863K10.7 expression is observed. Does this perturbation lead to a significant difference in RP11-863K10.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-863K10.7 expression is observed. Does this perturbation lead to a significant difference in RP11-863K10.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP13-216E22.4. Does perturbing MRPL39 lead to a significant change in RP13-216E22.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP13-216E22.4. Does perturbing MRPL39 lead to a significant change in RP13-216E22.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of HOTAIRM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of HOTAIRM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in RP11-390B4.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in RP11-390B4.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5030,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Does this perturbation cause a significant change in CELF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Does this perturbation cause a significant change in CELF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of PTBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of PTBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and KHDC1L expression is quantified. Does this perturbation result in a significant change in KHDC1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and KHDC1L expression is quantified. Does this perturbation result in a significant change in KHDC1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
670,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Does this perturbation cause a significant change in MEX3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Does this perturbation cause a significant change in MEX3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and GPR146 expression is quantified. Does this perturbation result in a significant change in GPR146 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and GPR146 expression is quantified. Does this perturbation result in a significant change in GPR146 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Determine whether C6orf120 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Determine whether C6orf120 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and GCKR expression is quantified. Does this perturbation result in a significant change in GCKR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and GCKR expression is quantified. Does this perturbation result in a significant change in GCKR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PTPRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PTPRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SNRNP25 expression is quantified. Does this perturbation result in a significant change in SNRNP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SNRNP25 expression is quantified. Does this perturbation result in a significant change in SNRNP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of KIAA1731. Does this perturbation cause a significant change in KIAA1731 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of KIAA1731. Does this perturbation cause a significant change in KIAA1731 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of SBF2. Does this perturbation cause a significant change in SBF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of SBF2. Does this perturbation cause a significant change in SBF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5073,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ERP29 expression is observed. Does this perturbation lead to a significant difference in ERP29 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ERP29 expression is observed. Does this perturbation lead to a significant difference in ERP29 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4523,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ATF7IP2 expression is observed. Does this perturbation lead to a significant difference in ATF7IP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ATF7IP2 expression is observed. Does this perturbation lead to a significant difference in ATF7IP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1408,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4560,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Does this perturbation cause a significant change in WDR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Does this perturbation cause a significant change in WDR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3638,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor SOBP expression. Decide whether this perturbation leads to a significant alteration in SOBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor SOBP expression. Decide whether this perturbation leads to a significant alteration in SOBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TTC32. Does perturbing TTI1 lead to a significant change in TTC32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TTC32. Does perturbing TTI1 lead to a significant change in TTC32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2138,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SLBP expression. Decide whether this perturbation leads to a significant alteration in SLBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SLBP expression. Decide whether this perturbation leads to a significant alteration in SLBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and HPCAL1 expression is quantified. Does this perturbation result in a significant change in HPCAL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and HPCAL1 expression is quantified. Does this perturbation result in a significant change in HPCAL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PTPN11 expression is quantified. Does this perturbation result in a significant change in PTPN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PTPN11 expression is quantified. Does this perturbation result in a significant change in PTPN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of IL2RB. Does perturbing TMED10 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of IL2RB. Does perturbing TMED10 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1660,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Does this perturbation cause a significant change in RP11-247A12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Does this perturbation cause a significant change in RP11-247A12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2633,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and HAGH expression is observed. Does this perturbation lead to a significant difference in HAGH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and HAGH expression is observed. Does this perturbation lead to a significant difference in HAGH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Determine whether GATA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Determine whether GATA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3213,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TTC32 expression is observed. Does this perturbation lead to a significant difference in TTC32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TTC32 expression is observed. Does this perturbation lead to a significant difference in TTC32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CTBS. Does perturbing PPWD1 lead to a significant change in CTBS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CTBS. Does perturbing PPWD1 lead to a significant change in CTBS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TRIM24 expression is measured. Determine whether TRIM24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TRIM24 expression is measured. Determine whether TRIM24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1923,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and AKAP11 expression is observed. Does this perturbation lead to a significant difference in AKAP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and AKAP11 expression is observed. Does this perturbation lead to a significant difference in AKAP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of USP37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of USP37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and RP11-573D15.2 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and RP11-573D15.2 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of CDRT4. Does this perturbation cause a significant change in CDRT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of CDRT4. Does this perturbation cause a significant change in CDRT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2850,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Does this perturbation cause a significant change in OXLD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Does this perturbation cause a significant change in OXLD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of POLR2J3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of POLR2J3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-227G15.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-227G15.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZMYND8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZMYND8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
763,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and HLA-AS1 expression is observed. Does this perturbation lead to a significant difference in HLA-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and HLA-AS1 expression is observed. Does this perturbation lead to a significant difference in HLA-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2003,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and C1GALT1 expression is observed. Does this perturbation lead to a significant difference in C1GALT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and C1GALT1 expression is observed. Does this perturbation lead to a significant difference in C1GALT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CHD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CHD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of TOB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of TOB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in LIMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in LIMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Determine whether RP11-247A12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Determine whether RP11-247A12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of RGS3. Does perturbing SEC61B lead to a significant change in RGS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of RGS3. Does perturbing SEC61B lead to a significant change in RGS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CMTM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CMTM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Determine whether PIK3R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Determine whether PIK3R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1263,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and HOTAIRM1 expression is observed. Does this perturbation lead to a significant difference in HOTAIRM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and HOTAIRM1 expression is observed. Does this perturbation lead to a significant difference in HOTAIRM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in SERPINH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in SERPINH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1568,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor DOCK8 expression. Decide whether this perturbation leads to a significant alteration in DOCK8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor DOCK8 expression. Decide whether this perturbation leads to a significant alteration in DOCK8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of PHF21A. Does this perturbation cause a significant change in PHF21A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of PHF21A. Does this perturbation cause a significant change in PHF21A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
94,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-141B14.1. Does this perturbation cause a significant change in RP11-141B14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-141B14.1. Does this perturbation cause a significant change in RP11-141B14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4843,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EPS15 expression is observed. Does this perturbation lead to a significant difference in EPS15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EPS15 expression is observed. Does this perturbation lead to a significant difference in EPS15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in GOT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in GOT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is quantified. Does this perturbation result in a significant change in RP13-216E22.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is quantified. Does this perturbation result in a significant change in RP13-216E22.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1533,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and C12orf44 expression is observed. Does this perturbation lead to a significant difference in C12orf44 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and C12orf44 expression is observed. Does this perturbation lead to a significant difference in C12orf44 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2798,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDK13 expression is quantified. Does this perturbation result in a significant change in CDK13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDK13 expression is quantified. Does this perturbation result in a significant change in CDK13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CHST12 expression is measured. Determine whether CHST12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CHST12 expression is measured. Determine whether CHST12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1158,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SLC37A1 expression. Decide whether this perturbation leads to a significant alteration in SLC37A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SLC37A1 expression. Decide whether this perturbation leads to a significant alteration in SLC37A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3068,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PHF19 expression. Decide whether this perturbation leads to a significant alteration in PHF19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PHF19 expression. Decide whether this perturbation leads to a significant alteration in PHF19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in OXLD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in OXLD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and C6orf120 expression is quantified. Does this perturbation result in a significant change in C6orf120 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and C6orf120 expression is quantified. Does this perturbation result in a significant change in C6orf120 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1303,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ITGB2 expression is observed. Does this perturbation lead to a significant difference in ITGB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ITGB2 expression is observed. Does this perturbation lead to a significant difference in ITGB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of LAMP2. Does perturbing HSD17B12 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of LAMP2. Does perturbing HSD17B12 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and H1FX expression is measured. Determine whether H1FX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and H1FX expression is measured. Determine whether H1FX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in H1FX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in H1FX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4178,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor FGF11 expression. Decide whether this perturbation leads to a significant alteration in FGF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor FGF11 expression. Decide whether this perturbation leads to a significant alteration in FGF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3443,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CCDC69 expression is observed. Does this perturbation lead to a significant difference in CCDC69 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CCDC69 expression is observed. Does this perturbation lead to a significant difference in CCDC69 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4083,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1888,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is quantified. Does this perturbation result in a significant change in RP11-181G12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is quantified. Does this perturbation result in a significant change in RP11-181G12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1520,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Does this perturbation cause a significant change in ZMYND8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Does this perturbation cause a significant change in ZMYND8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and UHRF1BP1L expression is quantified. Does this perturbation result in a significant change in UHRF1BP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and UHRF1BP1L expression is quantified. Does this perturbation result in a significant change in UHRF1BP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and IDS expression is measured. Determine whether IDS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and IDS expression is measured. Determine whether IDS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3303,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SMIM14 expression is observed. Does this perturbation lead to a significant difference in SMIM14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SMIM14 expression is observed. Does this perturbation lead to a significant difference in SMIM14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ROCK1 expression is measured. Determine whether ROCK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ROCK1 expression is measured. Determine whether ROCK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1453,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and LRIF1 expression is observed. Does this perturbation lead to a significant difference in LRIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and LRIF1 expression is observed. Does this perturbation lead to a significant difference in LRIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of LRIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of LRIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1498,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RP11-24F11.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-24F11.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RP11-24F11.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-24F11.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and CD58 expression is quantified. Does this perturbation result in a significant change in CD58 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and CD58 expression is quantified. Does this perturbation result in a significant change in CD58 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and FYTTD1 expression is quantified. Does this perturbation result in a significant change in FYTTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and FYTTD1 expression is quantified. Does this perturbation result in a significant change in FYTTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of TROAP. Does perturbing SARS lead to a significant change in TROAP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of TROAP. Does perturbing SARS lead to a significant change in TROAP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3610,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Does this perturbation cause a significant change in TIPARP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Does this perturbation cause a significant change in TIPARP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4380,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Does this perturbation cause a significant change in GALNT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Does this perturbation cause a significant change in GALNT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of IL32. Does this perturbation cause a significant change in IL32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of IL32. Does this perturbation cause a significant change in IL32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and IDS expression is quantified. Does this perturbation result in a significant change in IDS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and IDS expression is quantified. Does this perturbation result in a significant change in IDS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and PDRG1 expression is quantified. Does this perturbation result in a significant change in PDRG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and PDRG1 expression is quantified. Does this perturbation result in a significant change in PDRG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ARHGAP11A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ARHGAP11A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4973,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of SERPINH1. Does perturbing ATP5B lead to a significant change in SERPINH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of SERPINH1. Does perturbing ATP5B lead to a significant change in SERPINH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
138,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TET1 expression. Decide whether this perturbation leads to a significant alteration in TET1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TET1 expression. Decide whether this perturbation leads to a significant alteration in TET1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
758,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor TSNAXIP1 expression. Decide whether this perturbation leads to a significant alteration in TSNAXIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor TSNAXIP1 expression. Decide whether this perturbation leads to a significant alteration in TSNAXIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and C9orf64 expression is quantified. Does this perturbation result in a significant change in C9orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and C9orf64 expression is quantified. Does this perturbation result in a significant change in C9orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1338,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor RCBTB2 expression. Decide whether this perturbation leads to a significant alteration in RCBTB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor RCBTB2 expression. Decide whether this perturbation leads to a significant alteration in RCBTB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of PPM1N indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of PPM1N indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4490,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Does this perturbation cause a significant change in SMCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Does this perturbation cause a significant change in SMCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in RP11-90P5.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in RP11-90P5.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and CDCA3 expression is measured. Determine whether CDCA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and CDCA3 expression is measured. Determine whether CDCA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1190,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Does this perturbation cause a significant change in RP11-435O5.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Does this perturbation cause a significant change in RP11-435O5.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
653,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and POU2F2 expression is observed. Does this perturbation lead to a significant difference in POU2F2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and POU2F2 expression is observed. Does this perturbation lead to a significant difference in POU2F2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and SEPT5 expression is measured. Determine whether SEPT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and SEPT5 expression is measured. Determine whether SEPT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3183,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RNF8 expression is observed. Does this perturbation lead to a significant difference in RNF8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RNF8 expression is observed. Does this perturbation lead to a significant difference in RNF8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4733,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and MTPN expression is observed. Does this perturbation lead to a significant difference in MTPN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and MTPN expression is observed. Does this perturbation lead to a significant difference in MTPN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ATF6 expression is measured. Determine whether ATF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ATF6 expression is measured. Determine whether ATF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of BRWD3. Does perturbing DAD1 lead to a significant change in BRWD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of BRWD3. Does perturbing DAD1 lead to a significant change in BRWD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of VIM-AS1. Does perturbing IER3IP1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of VIM-AS1. Does perturbing IER3IP1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4080,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is measured. Determine whether SLC25A35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is measured. Determine whether SLC25A35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of NUFIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of NUFIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Determine whether RP11-119J18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Determine whether RP11-119J18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AC015987.1. Does this perturbation cause a significant change in AC015987.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AC015987.1. Does this perturbation cause a significant change in AC015987.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HMGCS1 expression is measured. Determine whether HMGCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HMGCS1 expression is measured. Determine whether HMGCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Determine whether LINC01031 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Determine whether LINC01031 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Determine whether HP1BP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Determine whether HP1BP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HERC2 expression is quantified. Does this perturbation result in a significant change in HERC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HERC2 expression is quantified. Does this perturbation result in a significant change in HERC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4020,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Does this perturbation cause a significant change in PIK3R3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Does this perturbation cause a significant change in PIK3R3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NOXA1 expression is quantified. Does this perturbation result in a significant change in NOXA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NOXA1 expression is quantified. Does this perturbation result in a significant change in NOXA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PSMC1. Does perturbing SEC61B lead to a significant change in PSMC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PSMC1. Does perturbing SEC61B lead to a significant change in PSMC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
210,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Does this perturbation cause a significant change in NFE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Does this perturbation cause a significant change in NFE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is quantified. Does this perturbation result in a significant change in RP11-334C17.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is quantified. Does this perturbation result in a significant change in RP11-334C17.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IFNGR1. Does perturbing MANF lead to a significant change in IFNGR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IFNGR1. Does perturbing MANF lead to a significant change in IFNGR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TSPAN33. Does perturbing SCYL1 lead to a significant change in TSPAN33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TSPAN33. Does perturbing SCYL1 lead to a significant change in TSPAN33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Determine whether FAM114A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Determine whether FAM114A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2263,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and C6orf120 expression is observed. Does this perturbation lead to a significant difference in C6orf120 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and C6orf120 expression is observed. Does this perturbation lead to a significant difference in C6orf120 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and C12orf23 expression is quantified. Does this perturbation result in a significant change in C12orf23 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and C12orf23 expression is quantified. Does this perturbation result in a significant change in C12orf23 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of S100A10. Does this perturbation cause a significant change in S100A10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of S100A10. Does this perturbation cause a significant change in S100A10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and TAGLN expression is quantified. Does this perturbation result in a significant change in TAGLN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and TAGLN expression is quantified. Does this perturbation result in a significant change in TAGLN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1038,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor TLN1 expression. Decide whether this perturbation leads to a significant alteration in TLN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor TLN1 expression. Decide whether this perturbation leads to a significant alteration in TLN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of SLC26A1. Does perturbing DERL2 lead to a significant change in SLC26A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of SLC26A1. Does perturbing DERL2 lead to a significant change in SLC26A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2783,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1720,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and TOB2 expression is quantified. Does this perturbation result in a significant change in TOB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and TOB2 expression is quantified. Does this perturbation result in a significant change in TOB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4278,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor IDS expression. Decide whether this perturbation leads to a significant alteration in IDS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor IDS expression. Decide whether this perturbation leads to a significant alteration in IDS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3438,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP5 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP5 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of AC005540.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of AC005540.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is measured. Determine whether RP11-247A12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is measured. Determine whether RP11-247A12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Determine whether ZNF678 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Determine whether ZNF678 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ESCO1 expression is quantified. Does this perturbation result in a significant change in ESCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ESCO1 expression is quantified. Does this perturbation result in a significant change in ESCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TET1 expression is quantified. Does this perturbation result in a significant change in TET1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TET1 expression is quantified. Does this perturbation result in a significant change in TET1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of C10orf32. Does this perturbation cause a significant change in C10orf32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of C10orf32. Does this perturbation cause a significant change in C10orf32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and DDX6 expression is quantified. Does this perturbation result in a significant change in DDX6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and DDX6 expression is quantified. Does this perturbation result in a significant change in DDX6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-789C1.1 expression is measured. Determine whether RP11-789C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-789C1.1 expression is measured. Determine whether RP11-789C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3113,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and NXF1 expression is observed. Does this perturbation lead to a significant difference in NXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and NXF1 expression is observed. Does this perturbation lead to a significant difference in NXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of WARS. Does this perturbation cause a significant change in WARS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of WARS. Does this perturbation cause a significant change in WARS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AC007038.7 expression is quantified. Does this perturbation result in a significant change in AC007038.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AC007038.7 expression is quantified. Does this perturbation result in a significant change in AC007038.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2170,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Does this perturbation cause a significant change in LRRC4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Does this perturbation cause a significant change in LRRC4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RASGRP2 expression is measured. Determine whether RASGRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RASGRP2 expression is measured. Determine whether RASGRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Determine whether SLC37A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Determine whether SLC37A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is quantified. Does this perturbation result in a significant change in RP11-212I21.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is quantified. Does this perturbation result in a significant change in RP11-212I21.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2720,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SIGLEC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SIGLEC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CLINT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CLINT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in CTD-2267D19.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in CTD-2267D19.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
158,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor CTSF expression. Decide whether this perturbation leads to a significant alteration in CTSF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor CTSF expression. Decide whether this perturbation leads to a significant alteration in CTSF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of KIF4A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of KIF4A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HIST1H1E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HIST1H1E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Determine whether NPAT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Determine whether NPAT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-499F3.2 expression is measured. Determine whether RP11-499F3.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-499F3.2 expression is measured. Determine whether RP11-499F3.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4700,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4188,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ANKRD33 expression. Decide whether this perturbation leads to a significant alteration in ANKRD33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ANKRD33 expression. Decide whether this perturbation leads to a significant alteration in ANKRD33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and PSORS1C1 expression is measured. Determine whether PSORS1C1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and PSORS1C1 expression is measured. Determine whether PSORS1C1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4818,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor MBNL1 expression. Decide whether this perturbation leads to a significant alteration in MBNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor MBNL1 expression. Decide whether this perturbation leads to a significant alteration in MBNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1573,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
160,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Does this perturbation cause a significant change in RIMS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Does this perturbation cause a significant change in RIMS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DUT expression is measured. Determine whether DUT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DUT expression is measured. Determine whether DUT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in KLF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in KLF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3318,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EGLN3 expression. Decide whether this perturbation leads to a significant alteration in EGLN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EGLN3 expression. Decide whether this perturbation leads to a significant alteration in EGLN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of PIK3R1. Does this perturbation cause a significant change in PIK3R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of PIK3R1. Does this perturbation cause a significant change in PIK3R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4873,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and S100A10 expression is observed. Does this perturbation lead to a significant difference in S100A10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and S100A10 expression is observed. Does this perturbation lead to a significant difference in S100A10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
14,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
580,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Does this perturbation cause a significant change in MYH7B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Does this perturbation cause a significant change in MYH7B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3143,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and DYNC1H1 expression is observed. Does this perturbation lead to a significant difference in DYNC1H1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and DYNC1H1 expression is observed. Does this perturbation lead to a significant difference in DYNC1H1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of RP11-430H10.1. Does perturbing P4HB lead to a significant change in RP11-430H10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of RP11-430H10.1. Does perturbing P4HB lead to a significant change in RP11-430H10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
15,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of SETX. Does perturbing SRP72 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of SETX. Does perturbing SRP72 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of SETX. Does perturbing GBF1 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of SETX. Does perturbing GBF1 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
300,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Does this perturbation cause a significant change in RP11-423O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Does this perturbation cause a significant change in RP11-423O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Determine whether CD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Determine whether CD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of RTN2. Does this perturbation cause a significant change in RTN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of RTN2. Does this perturbation cause a significant change in RTN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and SLC26A1 expression is quantified. Does this perturbation result in a significant change in SLC26A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and SLC26A1 expression is quantified. Does this perturbation result in a significant change in SLC26A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Determine whether SEPT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Determine whether SEPT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in LTBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in LTBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Determine whether TRAPPC10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Determine whether TRAPPC10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3663,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and EP400 expression is observed. Does this perturbation lead to a significant difference in EP400 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and EP400 expression is observed. Does this perturbation lead to a significant difference in EP400 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is measured. Determine whether RP11-322J23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is measured. Determine whether RP11-322J23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in AC018878.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in AC018878.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and NOX5 expression is measured. Determine whether NOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and NOX5 expression is measured. Determine whether NOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CST7. Does this perturbation cause a significant change in CST7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CST7. Does this perturbation cause a significant change in CST7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4318,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor MED13 expression. Decide whether this perturbation leads to a significant alteration in MED13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor MED13 expression. Decide whether this perturbation leads to a significant alteration in MED13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ANKRD10. Does this perturbation cause a significant change in ANKRD10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ANKRD10. Does this perturbation cause a significant change in ANKRD10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TKTL1 expression is measured. Determine whether TKTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TKTL1 expression is measured. Determine whether TKTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
37,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of CASP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of CASP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and ZNF678 expression is measured. Determine whether ZNF678 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and ZNF678 expression is measured. Determine whether ZNF678 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and UBE2V1 expression is quantified. Does this perturbation result in a significant change in UBE2V1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and UBE2V1 expression is quantified. Does this perturbation result in a significant change in UBE2V1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of DDX3X. Does this perturbation cause a significant change in DDX3X expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of DDX3X. Does this perturbation cause a significant change in DDX3X expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2788,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2978,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor HPCAL1 expression. Decide whether this perturbation leads to a significant alteration in HPCAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor HPCAL1 expression. Decide whether this perturbation leads to a significant alteration in HPCAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of UHMK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of UHMK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ANKRD33 expression is measured. Determine whether ANKRD33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ANKRD33 expression is measured. Determine whether ANKRD33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1853,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and TRAPPC10 expression is observed. Does this perturbation lead to a significant difference in TRAPPC10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and TRAPPC10 expression is observed. Does this perturbation lead to a significant difference in TRAPPC10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of KDM1B. Does this perturbation cause a significant change in KDM1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of KDM1B. Does this perturbation cause a significant change in KDM1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ANKRD11 expression is measured. Determine whether ANKRD11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ANKRD11 expression is measured. Determine whether ANKRD11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and EIF4B expression is measured. Determine whether EIF4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and EIF4B expression is measured. Determine whether EIF4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2560,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Does this perturbation cause a significant change in SBF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Does this perturbation cause a significant change in SBF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EXOC3L2 expression is quantified. Does this perturbation result in a significant change in EXOC3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EXOC3L2 expression is quantified. Does this perturbation result in a significant change in EXOC3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of DDX6. Does this perturbation cause a significant change in DDX6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of DDX6. Does this perturbation cause a significant change in DDX6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ATP5EP2 expression is measured. Determine whether ATP5EP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ATP5EP2 expression is measured. Determine whether ATP5EP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4203,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4050,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Does this perturbation cause a significant change in RP11-15E18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Does this perturbation cause a significant change in RP11-15E18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1858,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor TRAPPC10 expression. Decide whether this perturbation leads to a significant alteration in TRAPPC10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor TRAPPC10 expression. Decide whether this perturbation leads to a significant alteration in TRAPPC10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is measured. Determine whether C1GALT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is measured. Determine whether C1GALT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HERC2 expression is measured. Determine whether HERC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HERC2 expression is measured. Determine whether HERC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of TNFRSF10B. Does perturbing TELO2 lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of TNFRSF10B. Does perturbing TELO2 lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-863K10.7. Does perturbing DARS lead to a significant change in RP11-863K10.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-863K10.7. Does perturbing DARS lead to a significant change in RP11-863K10.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of LINC01031 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of LINC01031 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and GOT1 expression is measured. Determine whether GOT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and GOT1 expression is measured. Determine whether GOT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of FYTTD1. Does perturbing HSPA9 lead to a significant change in FYTTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of FYTTD1. Does perturbing HSPA9 lead to a significant change in FYTTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IFNGR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IFNGR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of DUSP21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of DUSP21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of PIK3R3. Does perturbing CCND3 lead to a significant change in PIK3R3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of PIK3R3. Does perturbing CCND3 lead to a significant change in PIK3R3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4503,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and BIRC5 expression is observed. Does this perturbation lead to a significant difference in BIRC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and BIRC5 expression is observed. Does this perturbation lead to a significant difference in BIRC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3400,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Does this perturbation cause a significant change in C3AR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Does this perturbation cause a significant change in C3AR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of COPB1. Does perturbing TIMM23 lead to a significant change in COPB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of COPB1. Does perturbing TIMM23 lead to a significant change in COPB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and LRIF1 expression is quantified. Does this perturbation result in a significant change in LRIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and LRIF1 expression is quantified. Does this perturbation result in a significant change in LRIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and CD46 expression is measured. Determine whether CD46 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and CD46 expression is measured. Determine whether CD46 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of GNPTG. Does perturbing SARS lead to a significant change in GNPTG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of GNPTG. Does perturbing SARS lead to a significant change in GNPTG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4580,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
588,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor MYH7B expression. Decide whether this perturbation leads to a significant alteration in MYH7B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor MYH7B expression. Decide whether this perturbation leads to a significant alteration in MYH7B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ARSA expression is measured. Determine whether ARSA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ARSA expression is measured. Determine whether ARSA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3810,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Does this perturbation cause a significant change in RP11-445H22.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Does this perturbation cause a significant change in RP11-445H22.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of NFAT5. Does this perturbation cause a significant change in NFAT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of NFAT5. Does this perturbation cause a significant change in NFAT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5033,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and CELF6 expression is observed. Does this perturbation lead to a significant difference in CELF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and CELF6 expression is observed. Does this perturbation lead to a significant difference in CELF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ATP6AP2. Does perturbing ATP5B lead to a significant change in ATP6AP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ATP6AP2. Does perturbing ATP5B lead to a significant change in ATP6AP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2703,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RAI14 expression is observed. Does this perturbation lead to a significant difference in RAI14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RAI14 expression is observed. Does this perturbation lead to a significant difference in RAI14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of RP11-322J23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of RP11-322J23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and PPP4R2 expression is measured. Determine whether PPP4R2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and PPP4R2 expression is measured. Determine whether PPP4R2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5090,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Does this perturbation cause a significant change in TGOLN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Does this perturbation cause a significant change in TGOLN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2658,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IFNGR1 expression. Decide whether this perturbation leads to a significant alteration in IFNGR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IFNGR1 expression. Decide whether this perturbation leads to a significant alteration in IFNGR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of SEPT5. Does perturbing SRP68 lead to a significant change in SEPT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of SEPT5. Does perturbing SRP68 lead to a significant change in SEPT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2620,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Does this perturbation cause a significant change in MORF4L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Does this perturbation cause a significant change in MORF4L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of RP11-666A20.4. Does perturbing CHERP lead to a significant change in RP11-666A20.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of RP11-666A20.4. Does perturbing CHERP lead to a significant change in RP11-666A20.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
540,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1113,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and GOT1 expression is observed. Does this perturbation lead to a significant difference in GOT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and GOT1 expression is observed. Does this perturbation lead to a significant difference in GOT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and RSL24D1 expression is measured. Determine whether RSL24D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and RSL24D1 expression is measured. Determine whether RSL24D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2450,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Does this perturbation cause a significant change in CTNNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Does this perturbation cause a significant change in CTNNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in C17orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in C17orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Determine whether TSC22D4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Determine whether TSC22D4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RP11-685N10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RP11-685N10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in OPTN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in OPTN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in AC079466.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in AC079466.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of COPB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of COPB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of CELF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of CELF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and SERPING1 expression is measured. Determine whether SERPING1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and SERPING1 expression is measured. Determine whether SERPING1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in FCGRT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in FCGRT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2048,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ZNF789. Does this perturbation cause a significant change in ZNF789 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ZNF789. Does this perturbation cause a significant change in ZNF789 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Determine whether ANXA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Determine whether ANXA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2508,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor UFD1L expression. Decide whether this perturbation leads to a significant alteration in UFD1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor UFD1L expression. Decide whether this perturbation leads to a significant alteration in UFD1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2020,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Does this perturbation cause a significant change in ABI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Does this perturbation cause a significant change in ABI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2368,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor FYTTD1 expression. Decide whether this perturbation leads to a significant alteration in FYTTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor FYTTD1 expression. Decide whether this perturbation leads to a significant alteration in FYTTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Determine whether RGS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Determine whether RGS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZNF292. Does perturbing SEL1L lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZNF292. Does perturbing SEL1L lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of CTSF. Does perturbing BHLHE40 lead to a significant change in CTSF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of CTSF. Does perturbing BHLHE40 lead to a significant change in CTSF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4143,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of BACH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of BACH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2250,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Does this perturbation cause a significant change in AC015987.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Does this perturbation cause a significant change in AC015987.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and GALNT7 expression is quantified. Does this perturbation result in a significant change in GALNT7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and GALNT7 expression is quantified. Does this perturbation result in a significant change in GALNT7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Determine whether PSORS1C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Determine whether PSORS1C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of KANSL1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of KANSL1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
788,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor WHAMM expression. Decide whether this perturbation leads to a significant alteration in WHAMM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor WHAMM expression. Decide whether this perturbation leads to a significant alteration in WHAMM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of ANKLE2. Does this perturbation cause a significant change in ANKLE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of ANKLE2. Does this perturbation cause a significant change in ANKLE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4753,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2453,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and CTNNB1 expression is observed. Does this perturbation lead to a significant difference in CTNNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and CTNNB1 expression is observed. Does this perturbation lead to a significant difference in CTNNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Determine whether WDR72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Determine whether WDR72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
578,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor CTD-2001C12.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2001C12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor CTD-2001C12.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2001C12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of RGS3. Does this perturbation cause a significant change in RGS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of RGS3. Does this perturbation cause a significant change in RGS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3700,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Does this perturbation cause a significant change in PARP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Does this perturbation cause a significant change in PARP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and HOTAIRM1 expression is quantified. Does this perturbation result in a significant change in HOTAIRM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and HOTAIRM1 expression is quantified. Does this perturbation result in a significant change in HOTAIRM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of RP11-181G12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of RP11-181G12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1828,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EIF3A. Does perturbing XRN1 lead to a significant change in EIF3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EIF3A. Does perturbing XRN1 lead to a significant change in EIF3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is measured. Determine whether RP11-363D14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is measured. Determine whether RP11-363D14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1988,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor KLF3 expression. Decide whether this perturbation leads to a significant alteration in KLF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor KLF3 expression. Decide whether this perturbation leads to a significant alteration in KLF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
773,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and JUND expression is observed. Does this perturbation lead to a significant difference in JUND expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and JUND expression is observed. Does this perturbation lead to a significant difference in JUND expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of RAD51AP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of RAD51AP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1930,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
638,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor VPS41 expression. Decide whether this perturbation leads to a significant alteration in VPS41 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor VPS41 expression. Decide whether this perturbation leads to a significant alteration in VPS41 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and RPL39 expression is measured. Determine whether RPL39 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and RPL39 expression is measured. Determine whether RPL39 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2190,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Does this perturbation cause a significant change in SLC26A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Does this perturbation cause a significant change in SLC26A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PDE4D expression is quantified. Does this perturbation result in a significant change in PDE4D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PDE4D expression is quantified. Does this perturbation result in a significant change in PDE4D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CTSV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CTSV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PIK3IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PIK3IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CD9 expression is measured. Determine whether CD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CD9 expression is measured. Determine whether CD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1713,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EPB42 expression is observed. Does this perturbation lead to a significant difference in EPB42 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EPB42 expression is observed. Does this perturbation lead to a significant difference in EPB42 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and KCNH7 expression is quantified. Does this perturbation result in a significant change in KCNH7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and KCNH7 expression is quantified. Does this perturbation result in a significant change in KCNH7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and BRWD3 expression is quantified. Does this perturbation result in a significant change in BRWD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and BRWD3 expression is quantified. Does this perturbation result in a significant change in BRWD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of LTN1. Does perturbing ARHGAP22 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of LTN1. Does perturbing ARHGAP22 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Determine whether CD83 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Determine whether CD83 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3473,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and BACH2 expression is observed. Does this perturbation lead to a significant difference in BACH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and BACH2 expression is observed. Does this perturbation lead to a significant difference in BACH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CLDN11. Does perturbing DHDDS lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CLDN11. Does perturbing DHDDS lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of HP1BP3. Does perturbing HARS lead to a significant change in HP1BP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of HP1BP3. Does perturbing HARS lead to a significant change in HP1BP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HERC2. Does this perturbation cause a significant change in HERC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HERC2. Does this perturbation cause a significant change in HERC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Determine whether EXO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Determine whether EXO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ABI2 expression is measured. Determine whether ABI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ABI2 expression is measured. Determine whether ABI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ZXDA. Does perturbing SLC35B1 lead to a significant change in ZXDA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ZXDA. Does perturbing SLC35B1 lead to a significant change in ZXDA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZMYND8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZMYND8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is quantified. Does this perturbation result in a significant change in AC015987.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is quantified. Does this perturbation result in a significant change in AC015987.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3298,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor GS1-166A23.1 expression. Decide whether this perturbation leads to a significant alteration in GS1-166A23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor GS1-166A23.1 expression. Decide whether this perturbation leads to a significant alteration in GS1-166A23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3673,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ZC3H7A expression is observed. Does this perturbation lead to a significant difference in ZC3H7A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ZC3H7A expression is observed. Does this perturbation lead to a significant difference in ZC3H7A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PDE9A. Does this perturbation cause a significant change in PDE9A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PDE9A. Does this perturbation cause a significant change in PDE9A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AMOTL1. Does this perturbation cause a significant change in AMOTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AMOTL1. Does this perturbation cause a significant change in AMOTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3683,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and SLC27A2 expression is observed. Does this perturbation lead to a significant difference in SLC27A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and SLC27A2 expression is observed. Does this perturbation lead to a significant difference in SLC27A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4780,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Does this perturbation cause a significant change in PDE3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Does this perturbation cause a significant change in PDE3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is quantified. Does this perturbation result in a significant change in RP11-322J23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is quantified. Does this perturbation result in a significant change in RP11-322J23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in RTN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in RTN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1103,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of KLF3. Does perturbing GNPNAT1 lead to a significant change in KLF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of KLF3. Does perturbing GNPNAT1 lead to a significant change in KLF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Determine whether NAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Determine whether NAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Determine whether THBS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Determine whether THBS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of DOCK11. Does perturbing EIF2B4 lead to a significant change in DOCK11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of DOCK11. Does perturbing EIF2B4 lead to a significant change in DOCK11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3768,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor RNF19A expression. Decide whether this perturbation leads to a significant alteration in RNF19A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor RNF19A expression. Decide whether this perturbation leads to a significant alteration in RNF19A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2590,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Does this perturbation cause a significant change in RP11-471M2.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Does this perturbation cause a significant change in RP11-471M2.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and CD46 expression is quantified. Does this perturbation result in a significant change in CD46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and CD46 expression is quantified. Does this perturbation result in a significant change in CD46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Determine whether RP11-61E11.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Determine whether RP11-61E11.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and CRNDE expression is measured. Determine whether CRNDE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and CRNDE expression is measured. Determine whether CRNDE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ESCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ESCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Determine whether CHST12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Determine whether CHST12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PDE3B. Does perturbing DNAJC19 lead to a significant change in PDE3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PDE3B. Does perturbing DNAJC19 lead to a significant change in PDE3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and POU2F2 expression is quantified. Does this perturbation result in a significant change in POU2F2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and POU2F2 expression is quantified. Does this perturbation result in a significant change in POU2F2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4943,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IFNGR1 expression is measured. Determine whether IFNGR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IFNGR1 expression is measured. Determine whether IFNGR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3273,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and TSC22D4 expression is observed. Does this perturbation lead to a significant difference in TSC22D4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and TSC22D4 expression is observed. Does this perturbation lead to a significant difference in TSC22D4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Determine whether HERPUD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Determine whether HERPUD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
368,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor DOCK11 expression. Decide whether this perturbation leads to a significant alteration in DOCK11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor DOCK11 expression. Decide whether this perturbation leads to a significant alteration in DOCK11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and GNPTG expression is quantified. Does this perturbation result in a significant change in GNPTG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and GNPTG expression is quantified. Does this perturbation result in a significant change in GNPTG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of SLFNL1. Does this perturbation cause a significant change in SLFNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of SLFNL1. Does this perturbation cause a significant change in SLFNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in NFE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in NFE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
803,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and COPB1 expression is observed. Does this perturbation lead to a significant difference in COPB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and COPB1 expression is observed. Does this perturbation lead to a significant difference in COPB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ITGB2. Does perturbing QARS lead to a significant change in ITGB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ITGB2. Does perturbing QARS lead to a significant change in ITGB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of NAV2. Does perturbing CARS lead to a significant change in NAV2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of NAV2. Does perturbing CARS lead to a significant change in NAV2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1778,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor SDF4 expression. Decide whether this perturbation leads to a significant alteration in SDF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor SDF4 expression. Decide whether this perturbation leads to a significant alteration in SDF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of RP11-304M2.5. Does perturbing DHDDS lead to a significant change in RP11-304M2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of RP11-304M2.5. Does perturbing DHDDS lead to a significant change in RP11-304M2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SDF4. Does perturbing MTHFD1 lead to a significant change in SDF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SDF4. Does perturbing MTHFD1 lead to a significant change in SDF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ANKRD10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ANKRD10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2528,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor RNF139-AS1 expression. Decide whether this perturbation leads to a significant alteration in RNF139-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor RNF139-AS1 expression. Decide whether this perturbation leads to a significant alteration in RNF139-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2643,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IDH3A expression is observed. Does this perturbation lead to a significant difference in IDH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IDH3A expression is observed. Does this perturbation lead to a significant difference in IDH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of FAM212A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of FAM212A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2540,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Does this perturbation cause a significant change in ZP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Does this perturbation cause a significant change in ZP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and DOCK8 expression is quantified. Does this perturbation result in a significant change in DOCK8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and DOCK8 expression is quantified. Does this perturbation result in a significant change in DOCK8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AMOTL1 expression is measured. Determine whether AMOTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AMOTL1 expression is measured. Determine whether AMOTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ANKRD11. Does perturbing SEC61G lead to a significant change in ANKRD11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ANKRD11. Does perturbing SEC61G lead to a significant change in ANKRD11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of KCTD19. Does this perturbation cause a significant change in KCTD19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of KCTD19. Does this perturbation cause a significant change in KCTD19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
913,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HIST1H3D expression is observed. Does this perturbation lead to a significant difference in HIST1H3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HIST1H3D expression is observed. Does this perturbation lead to a significant difference in HIST1H3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
500,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Does this perturbation cause a significant change in PTPN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Does this perturbation cause a significant change in PTPN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4008,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1540,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and C3AR1 expression is measured. Determine whether C3AR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and C3AR1 expression is measured. Determine whether C3AR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in S100A10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in S100A10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of SHOX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of SHOX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CPQ expression is measured. Determine whether CPQ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CPQ expression is measured. Determine whether CPQ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2808,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of DST. Does this perturbation cause a significant change in DST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of DST. Does this perturbation cause a significant change in DST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Determine whether RP11-24F11.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Determine whether RP11-24F11.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZMYND8 expression is measured. Determine whether ZMYND8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZMYND8 expression is measured. Determine whether ZMYND8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3600,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of MARCH8. Does this perturbation cause a significant change in MARCH8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of MARCH8. Does this perturbation cause a significant change in MARCH8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CTBS expression is measured. Determine whether CTBS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CTBS expression is measured. Determine whether CTBS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in HIST1H1D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in HIST1H1D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Determine whether TLN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Determine whether TLN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
46,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Determine whether LPAR5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Determine whether LPAR5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CENPC. Does perturbing DERL2 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CENPC. Does perturbing DERL2 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1538,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor C12orf44 expression. Decide whether this perturbation leads to a significant alteration in C12orf44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor C12orf44 expression. Decide whether this perturbation leads to a significant alteration in C12orf44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in MTPN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in MTPN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IDH3A expression is measured. Determine whether IDH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IDH3A expression is measured. Determine whether IDH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and ACRV1 expression is quantified. Does this perturbation result in a significant change in ACRV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and ACRV1 expression is quantified. Does this perturbation result in a significant change in ACRV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CTC-308K20.1. Does perturbing SPCS2 lead to a significant change in CTC-308K20.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CTC-308K20.1. Does perturbing SPCS2 lead to a significant change in CTC-308K20.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
60,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Does this perturbation cause a significant change in RIOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Does this perturbation cause a significant change in RIOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IFNGR1 expression is quantified. Does this perturbation result in a significant change in IFNGR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IFNGR1 expression is quantified. Does this perturbation result in a significant change in IFNGR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2418,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4593,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and LINC00862 expression is observed. Does this perturbation lead to a significant difference in LINC00862 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and LINC00862 expression is observed. Does this perturbation lead to a significant difference in LINC00862 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of PITPNB. Does perturbing PTDSS1 lead to a significant change in PITPNB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of PITPNB. Does perturbing PTDSS1 lead to a significant change in PITPNB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
880,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Does this perturbation cause a significant change in GATA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Does this perturbation cause a significant change in GATA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EPB42 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EPB42 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of GRN. Does this perturbation cause a significant change in GRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of GRN. Does this perturbation cause a significant change in GRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1420,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Does this perturbation cause a significant change in RP11-61E11.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Does this perturbation cause a significant change in RP11-61E11.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1963,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PTPRC expression is measured. Determine whether PTPRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PTPRC expression is measured. Determine whether PTPRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
558,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor OPTN expression. Decide whether this perturbation leads to a significant alteration in OPTN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor OPTN expression. Decide whether this perturbation leads to a significant alteration in OPTN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
433,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CLINT1 expression is observed. Does this perturbation lead to a significant difference in CLINT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CLINT1 expression is observed. Does this perturbation lead to a significant difference in CLINT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2203,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CST7 expression is observed. Does this perturbation lead to a significant difference in CST7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CST7 expression is observed. Does this perturbation lead to a significant difference in CST7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and PGM3 expression is quantified. Does this perturbation result in a significant change in PGM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and PGM3 expression is quantified. Does this perturbation result in a significant change in PGM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Determine whether MORC2-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Determine whether MORC2-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3963,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of RNF139-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of RNF139-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2323,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and H3F3B expression is observed. Does this perturbation lead to a significant difference in H3F3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and H3F3B expression is observed. Does this perturbation lead to a significant difference in H3F3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Determine whether KLK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Determine whether KLK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TTC32 expression is quantified. Does this perturbation result in a significant change in TTC32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TTC32 expression is quantified. Does this perturbation result in a significant change in TTC32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2253,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AC015987.1 expression is observed. Does this perturbation lead to a significant difference in AC015987.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AC015987.1 expression is observed. Does this perturbation lead to a significant difference in AC015987.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NUF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NUF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CMTM6. Does this perturbation cause a significant change in CMTM6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CMTM6. Does this perturbation cause a significant change in CMTM6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1668,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor RP11-247A12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-247A12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor RP11-247A12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-247A12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4258,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor PAK1IP1 expression. Decide whether this perturbation leads to a significant alteration in PAK1IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor PAK1IP1 expression. Decide whether this perturbation leads to a significant alteration in PAK1IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4980,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Does this perturbation cause a significant change in UHMK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Does this perturbation cause a significant change in UHMK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Determine whether FCGRT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Determine whether FCGRT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and RNF19A expression is quantified. Does this perturbation result in a significant change in RNF19A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and RNF19A expression is quantified. Does this perturbation result in a significant change in RNF19A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of TMOD3. Does perturbing SEL1L lead to a significant change in TMOD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of TMOD3. Does perturbing SEL1L lead to a significant change in TMOD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is quantified. Does this perturbation result in a significant change in RP11-132A1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is quantified. Does this perturbation result in a significant change in RP11-132A1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
760,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Does this perturbation cause a significant change in HLA-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Does this perturbation cause a significant change in HLA-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and TACC3 expression is quantified. Does this perturbation result in a significant change in TACC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and TACC3 expression is quantified. Does this perturbation result in a significant change in TACC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CTCFL expression is measured. Determine whether CTCFL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CTCFL expression is measured. Determine whether CTCFL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and SDF4 expression is measured. Determine whether SDF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and SDF4 expression is measured. Determine whether SDF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and JARID2 expression is measured. Determine whether JARID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and JARID2 expression is measured. Determine whether JARID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Determine whether ANPEP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Determine whether ANPEP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of DNTTIP2. Does this perturbation cause a significant change in DNTTIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of DNTTIP2. Does this perturbation cause a significant change in DNTTIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3868,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GLG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GLG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CTSV. Does perturbing MANF lead to a significant change in CTSV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CTSV. Does perturbing MANF lead to a significant change in CTSV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4350,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Does this perturbation cause a significant change in ANKRD10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Does this perturbation cause a significant change in ANKRD10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CTSV. Does this perturbation cause a significant change in CTSV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CTSV. Does this perturbation cause a significant change in CTSV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in C19orf59 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in C19orf59 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is measured. Determine whether KCNQ1OT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is measured. Determine whether KCNQ1OT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of IL13RA1. Does perturbing HSPA9 lead to a significant change in IL13RA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of IL13RA1. Does perturbing HSPA9 lead to a significant change in IL13RA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of SEPT5. Does this perturbation cause a significant change in SEPT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of SEPT5. Does this perturbation cause a significant change in SEPT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZNF280B. Does perturbing SOCS1 lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZNF280B. Does perturbing SOCS1 lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of PAK1IP1. Does perturbing CHERP lead to a significant change in PAK1IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of PAK1IP1. Does perturbing CHERP lead to a significant change in PAK1IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1863,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and TACC3 expression is observed. Does this perturbation lead to a significant difference in TACC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and TACC3 expression is observed. Does this perturbation lead to a significant difference in TACC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NPDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NPDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Determine whether KIAA0922 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Determine whether KIAA0922 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of EBI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of EBI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and TSNAXIP1 expression is quantified. Does this perturbation result in a significant change in TSNAXIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and TSNAXIP1 expression is quantified. Does this perturbation result in a significant change in TSNAXIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3390,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Does this perturbation cause a significant change in TUBA1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Does this perturbation cause a significant change in TUBA1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of PIK3R3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of PIK3R3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3813,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and RP11-445H22.3 expression is observed. Does this perturbation lead to a significant difference in RP11-445H22.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and RP11-445H22.3 expression is observed. Does this perturbation lead to a significant difference in RP11-445H22.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1148,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SP100 expression. Decide whether this perturbation leads to a significant alteration in SP100 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SP100 expression. Decide whether this perturbation leads to a significant alteration in SP100 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of TACC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of TACC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of KCNE3. Does this perturbation cause a significant change in KCNE3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of KCNE3. Does this perturbation cause a significant change in KCNE3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and MS4A6E expression is quantified. Does this perturbation result in a significant change in MS4A6E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and MS4A6E expression is quantified. Does this perturbation result in a significant change in MS4A6E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and EP400 expression is measured. Determine whether EP400 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and EP400 expression is measured. Determine whether EP400 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5100,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Does this perturbation cause a significant change in PIK3R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Does this perturbation cause a significant change in PIK3R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2423,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of GDF11. Does perturbing EIF2B4 lead to a significant change in GDF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of GDF11. Does perturbing EIF2B4 lead to a significant change in GDF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Determine whether PSMD14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Determine whether PSMD14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and LINC00938 expression is quantified. Does this perturbation result in a significant change in LINC00938 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and LINC00938 expression is quantified. Does this perturbation result in a significant change in LINC00938 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of WHSC1. Does perturbing MRGBP lead to a significant change in WHSC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of WHSC1. Does perturbing MRGBP lead to a significant change in WHSC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Determine whether RP11-181G12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Determine whether RP11-181G12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1428,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor RP11-61E11.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-61E11.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor RP11-61E11.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-61E11.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HERC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HERC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Determine whether SDF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Determine whether SDF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of HIST1H2BC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of HIST1H2BC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and CRNDE expression is quantified. Does this perturbation result in a significant change in CRNDE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and CRNDE expression is quantified. Does this perturbation result in a significant change in CRNDE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SP100 expression is quantified. Does this perturbation result in a significant change in SP100 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SP100 expression is quantified. Does this perturbation result in a significant change in SP100 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and CELF6 expression is measured. Determine whether CELF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and CELF6 expression is measured. Determine whether CELF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of IL8. Does perturbing DDRGK1 lead to a significant change in IL8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of IL8. Does perturbing DDRGK1 lead to a significant change in IL8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in GCKR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in GCKR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Determine whether PPP4R2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Determine whether PPP4R2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4378,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor RP11-181G12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-181G12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor RP11-181G12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-181G12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ROBO1. Does this perturbation cause a significant change in ROBO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ROBO1. Does this perturbation cause a significant change in ROBO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HRK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HRK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in RP11-304M2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in RP11-304M2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in NFAT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in NFAT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Determine whether CTD-2001C12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Determine whether CTD-2001C12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and UQCRB expression is measured. Determine whether UQCRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and UQCRB expression is measured. Determine whether UQCRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Determine whether PTAR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Determine whether PTAR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of SERPINH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of SERPINH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2763,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDK13 expression is observed. Does this perturbation lead to a significant difference in CDK13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDK13 expression is observed. Does this perturbation lead to a significant difference in CDK13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
890,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Does this perturbation cause a significant change in APOL4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Does this perturbation cause a significant change in APOL4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4978,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of CTD-2020K17.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of CTD-2020K17.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of TLN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of TLN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of MS4A6E. Does this perturbation cause a significant change in MS4A6E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of MS4A6E. Does this perturbation cause a significant change in MS4A6E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RP11-24F11.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RP11-24F11.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HIST1H1E. Does this perturbation cause a significant change in HIST1H1E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HIST1H1E. Does this perturbation cause a significant change in HIST1H1E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of MTPN. Does this perturbation cause a significant change in MTPN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of MTPN. Does this perturbation cause a significant change in MTPN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1780,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Does this perturbation cause a significant change in KCNH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Does this perturbation cause a significant change in KCNH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ZEB1. Does this perturbation cause a significant change in ZEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ZEB1. Does this perturbation cause a significant change in ZEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
480,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and SKIL expression is measured. Determine whether SKIL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and SKIL expression is measured. Determine whether SKIL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ZFHX3. Does perturbing SEC61A1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ZFHX3. Does perturbing SEC61A1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RP11-16E12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RP11-16E12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and AC018878.3 expression is quantified. Does this perturbation result in a significant change in AC018878.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and AC018878.3 expression is quantified. Does this perturbation result in a significant change in AC018878.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
27,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3898,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor ACRV1 expression. Decide whether this perturbation leads to a significant alteration in ACRV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor ACRV1 expression. Decide whether this perturbation leads to a significant alteration in ACRV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of NFE2L3. Does perturbing XRN1 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of NFE2L3. Does perturbing XRN1 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4303,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and GCKR expression is observed. Does this perturbation lead to a significant difference in GCKR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and GCKR expression is observed. Does this perturbation lead to a significant difference in GCKR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2013,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and AC015987.2 expression is observed. Does this perturbation lead to a significant difference in AC015987.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and AC015987.2 expression is observed. Does this perturbation lead to a significant difference in AC015987.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of SOBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of SOBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is quantified. Does this perturbation result in a significant change in CTC-308K20.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is quantified. Does this perturbation result in a significant change in CTC-308K20.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Determine whether EIF3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Determine whether EIF3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3418,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor NOX5 expression. Decide whether this perturbation leads to a significant alteration in NOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor NOX5 expression. Decide whether this perturbation leads to a significant alteration in NOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2863,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PIK3IP1 expression is observed. Does this perturbation lead to a significant difference in PIK3IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PIK3IP1 expression is observed. Does this perturbation lead to a significant difference in PIK3IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of BACH2. Does perturbing KCTD16 lead to a significant change in BACH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of BACH2. Does perturbing KCTD16 lead to a significant change in BACH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of GNPTG. Does this perturbation cause a significant change in GNPTG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of GNPTG. Does this perturbation cause a significant change in GNPTG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of CD58. Does this perturbation cause a significant change in CD58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of CD58. Does this perturbation cause a significant change in CD58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is measured. Determine whether RP11-16E12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is measured. Determine whether RP11-16E12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RIMS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RIMS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ATF7IP2. Does this perturbation cause a significant change in ATF7IP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ATF7IP2. Does this perturbation cause a significant change in ATF7IP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
52,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and C6orf48 expression is quantified. Does this perturbation result in a significant change in C6orf48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and C6orf48 expression is quantified. Does this perturbation result in a significant change in C6orf48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
303,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and RP11-423O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-423O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and RP11-423O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-423O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and TLN1 expression is measured. Determine whether TLN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and TLN1 expression is measured. Determine whether TLN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2108,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PTAR1 expression. Decide whether this perturbation leads to a significant alteration in PTAR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PTAR1 expression. Decide whether this perturbation leads to a significant alteration in PTAR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Determine whether IL32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Determine whether IL32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Determine whether CFH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Determine whether CFH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of CD46. Does perturbing CHERP lead to a significant change in CD46 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of CD46. Does perturbing CHERP lead to a significant change in CD46 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of EP300. Does perturbing TTI2 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of EP300. Does perturbing TTI2 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
148,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RDH10 expression. Decide whether this perturbation leads to a significant alteration in RDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RDH10 expression. Decide whether this perturbation leads to a significant alteration in RDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in RP11-247A12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in RP11-247A12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of PPP4R2. Does this perturbation cause a significant change in PPP4R2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of PPP4R2. Does this perturbation cause a significant change in PPP4R2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PTAR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PTAR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
56,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Determine whether C6orf48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Determine whether C6orf48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in RBM12B-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in RBM12B-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Determine whether RP11-38P22.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Determine whether RP11-38P22.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
200,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Does this perturbation cause a significant change in KLK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Does this perturbation cause a significant change in KLK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ZNF429. Does this perturbation cause a significant change in ZNF429 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ZNF429. Does this perturbation cause a significant change in ZNF429 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Determine whether CDCA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Determine whether CDCA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of KCNH7. Does this perturbation cause a significant change in KCNH7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of KCNH7. Does this perturbation cause a significant change in KCNH7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and RP11-434H6.6 expression is measured. Determine whether RP11-434H6.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and RP11-434H6.6 expression is measured. Determine whether RP11-434H6.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and TMEM87B expression is measured. Determine whether TMEM87B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and TMEM87B expression is measured. Determine whether TMEM87B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in C12orf23 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in C12orf23 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CENPC. Does perturbing PPWD1 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CENPC. Does perturbing PPWD1 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-227G15.8 expression is measured. Determine whether RP11-227G15.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-227G15.8 expression is measured. Determine whether RP11-227G15.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3103,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PSMD14 expression is observed. Does this perturbation lead to a significant difference in PSMD14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PSMD14 expression is observed. Does this perturbation lead to a significant difference in PSMD14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Determine whether RAD51AP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Determine whether RAD51AP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Determine whether ARSA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Determine whether ARSA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1650,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Does this perturbation cause a significant change in EBI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Does this perturbation cause a significant change in EBI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of EBI3. Does this perturbation cause a significant change in EBI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of EBI3. Does this perturbation cause a significant change in EBI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Determine whether TTC32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Determine whether TTC32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SLBP. Does this perturbation cause a significant change in SLBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SLBP. Does this perturbation cause a significant change in SLBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ATP2A3. Does perturbing GMPPB lead to a significant change in ATP2A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ATP2A3. Does perturbing GMPPB lead to a significant change in ATP2A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Determine whether AMOTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Determine whether AMOTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5148,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor RAD51AP1 expression. Decide whether this perturbation leads to a significant alteration in RAD51AP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor RAD51AP1 expression. Decide whether this perturbation leads to a significant alteration in RAD51AP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in IL13RA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in IL13RA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of IL32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of IL32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and USP34 expression is measured. Determine whether USP34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and USP34 expression is measured. Determine whether USP34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Determine whether NUFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Determine whether NUFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and BRWD3 expression is measured. Determine whether BRWD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and BRWD3 expression is measured. Determine whether BRWD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2628,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor MORF4L2 expression. Decide whether this perturbation leads to a significant alteration in MORF4L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor MORF4L2 expression. Decide whether this perturbation leads to a significant alteration in MORF4L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
490,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Does this perturbation cause a significant change in LDLR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Does this perturbation cause a significant change in LDLR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in APOBEC3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in APOBEC3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1643,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and SERPINH1 expression is observed. Does this perturbation lead to a significant difference in SERPINH1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and SERPINH1 expression is observed. Does this perturbation lead to a significant difference in SERPINH1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
820,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Does this perturbation cause a significant change in TMEM87B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Does this perturbation cause a significant change in TMEM87B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of C12orf44. Does this perturbation cause a significant change in C12orf44 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of C12orf44. Does this perturbation cause a significant change in C12orf44 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TUBA1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TUBA1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and REST expression is quantified. Does this perturbation result in a significant change in REST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and REST expression is quantified. Does this perturbation result in a significant change in REST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Determine whether BRWD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Determine whether BRWD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CHD3. Does this perturbation cause a significant change in CHD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CHD3. Does this perturbation cause a significant change in CHD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and CCRL2 expression is quantified. Does this perturbation result in a significant change in CCRL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and CCRL2 expression is quantified. Does this perturbation result in a significant change in CCRL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Determine whether CTC-550B14.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Determine whether CTC-550B14.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KCNQ1OT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KCNQ1OT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP11-119J18.1. Does this perturbation cause a significant change in RP11-119J18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP11-119J18.1. Does this perturbation cause a significant change in RP11-119J18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of BAMBI. Does perturbing UFL1 lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of BAMBI. Does perturbing UFL1 lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of LTBP1. Does this perturbation cause a significant change in LTBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of LTBP1. Does this perturbation cause a significant change in LTBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of GCKR. Does this perturbation cause a significant change in GCKR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of GCKR. Does this perturbation cause a significant change in GCKR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3758,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA1432 expression. Decide whether this perturbation leads to a significant alteration in KIAA1432 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA1432 expression. Decide whether this perturbation leads to a significant alteration in KIAA1432 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2878,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor RGS3 expression. Decide whether this perturbation leads to a significant alteration in RGS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor RGS3 expression. Decide whether this perturbation leads to a significant alteration in RGS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ATP6V1B2. Does this perturbation cause a significant change in ATP6V1B2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ATP6V1B2. Does this perturbation cause a significant change in ATP6V1B2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in DUSP21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in DUSP21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Determine whether SKIL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Determine whether SKIL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
350,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2803,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AFF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AFF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3760,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Does this perturbation cause a significant change in RNF19A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Does this perturbation cause a significant change in RNF19A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of C10orf32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of C10orf32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3150,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Does this perturbation cause a significant change in SLC25A35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Does this perturbation cause a significant change in SLC25A35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2243,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AMOTL1 expression is observed. Does this perturbation lead to a significant difference in AMOTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AMOTL1 expression is observed. Does this perturbation lead to a significant difference in AMOTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PHF19. Does this perturbation cause a significant change in PHF19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PHF19. Does this perturbation cause a significant change in PHF19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC008074.3 expression is measured. Determine whether AC008074.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC008074.3 expression is measured. Determine whether AC008074.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of CTNNB1. Does this perturbation cause a significant change in CTNNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of CTNNB1. Does this perturbation cause a significant change in CTNNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
543,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and AKAP11 expression is quantified. Does this perturbation result in a significant change in AKAP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and AKAP11 expression is quantified. Does this perturbation result in a significant change in AKAP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1558,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor RP11-381O7.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-381O7.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor RP11-381O7.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-381O7.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in TROAP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in TROAP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
623,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and SAMM50 expression is observed. Does this perturbation lead to a significant difference in SAMM50 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and SAMM50 expression is observed. Does this perturbation lead to a significant difference in SAMM50 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4493,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and SMCO1 expression is observed. Does this perturbation lead to a significant difference in SMCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and SMCO1 expression is observed. Does this perturbation lead to a significant difference in SMCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Determine whether GOT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Determine whether GOT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2390,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Does this perturbation cause a significant change in RP11-254F7.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Does this perturbation cause a significant change in RP11-254F7.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Determine whether ATXN7L3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Determine whether ATXN7L3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in LINC00657 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in LINC00657 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP11-2H8.2. Does this perturbation cause a significant change in RP11-2H8.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP11-2H8.2. Does this perturbation cause a significant change in RP11-2H8.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2100,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Does this perturbation cause a significant change in PTAR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Does this perturbation cause a significant change in PTAR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Determine whether KCNJ13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Determine whether KCNJ13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and DDX6 expression is measured. Determine whether DDX6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and DDX6 expression is measured. Determine whether DDX6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1133,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
74,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of CEBPG. Does this perturbation cause a significant change in CEBPG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of CEBPG. Does this perturbation cause a significant change in CEBPG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of P4HA2. Does perturbing MRPL39 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of P4HA2. Does perturbing MRPL39 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ATAD2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ATAD2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MLEC expression is measured. Determine whether MLEC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MLEC expression is measured. Determine whether MLEC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP1-274L7.1. Does perturbing CCND3 lead to a significant change in RP1-274L7.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP1-274L7.1. Does perturbing CCND3 lead to a significant change in RP1-274L7.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CCDC69. Does this perturbation cause a significant change in CCDC69 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CCDC69. Does this perturbation cause a significant change in CCDC69 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ADAMTS10. Does this perturbation cause a significant change in ADAMTS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ADAMTS10. Does this perturbation cause a significant change in ADAMTS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2900,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Does this perturbation cause a significant change in VAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Does this perturbation cause a significant change in VAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Determine whether EGLN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Determine whether EGLN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
47,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of LPAR5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of LPAR5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1633,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and DNASE2 expression is observed. Does this perturbation lead to a significant difference in DNASE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and DNASE2 expression is observed. Does this perturbation lead to a significant difference in DNASE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3090,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Does this perturbation cause a significant change in GNPTG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Does this perturbation cause a significant change in GNPTG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Determine whether CD46 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Determine whether CD46 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Determine whether JUND shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Determine whether JUND shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ANPEP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ANPEP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4940,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Determine whether ABI2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Determine whether ABI2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SLBP. Does perturbing SLC39A7 lead to a significant change in SLBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SLBP. Does perturbing SLC39A7 lead to a significant change in SLBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and SPINK5 expression is measured. Determine whether SPINK5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and SPINK5 expression is measured. Determine whether SPINK5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
468,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ERV3-1 expression. Decide whether this perturbation leads to a significant alteration in ERV3-1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ERV3-1 expression. Decide whether this perturbation leads to a significant alteration in ERV3-1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PHF19 expression is measured. Determine whether PHF19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PHF19 expression is measured. Determine whether PHF19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3970,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Does this perturbation cause a significant change in SEC23IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Does this perturbation cause a significant change in SEC23IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of TLN1. Does this perturbation cause a significant change in TLN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of TLN1. Does this perturbation cause a significant change in TLN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and LRRC4B expression is measured. Determine whether LRRC4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and LRRC4B expression is measured. Determine whether LRRC4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5128,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CDT1 expression. Decide whether this perturbation leads to a significant alteration in CDT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CDT1 expression. Decide whether this perturbation leads to a significant alteration in CDT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1613,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and RP11-81A22.5 expression is observed. Does this perturbation lead to a significant difference in RP11-81A22.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and RP11-81A22.5 expression is observed. Does this perturbation lead to a significant difference in RP11-81A22.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ZEB2 expression is quantified. Does this perturbation result in a significant change in ZEB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ZEB2 expression is quantified. Does this perturbation result in a significant change in ZEB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CTD-2521M24.9. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CTD-2521M24.9. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3338,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor AP000688.8 expression. Decide whether this perturbation leads to a significant alteration in AP000688.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor AP000688.8 expression. Decide whether this perturbation leads to a significant alteration in AP000688.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SLC37A1 expression is measured. Determine whether SLC37A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SLC37A1 expression is measured. Determine whether SLC37A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is measured. Determine whether RP11-254F7.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is measured. Determine whether RP11-254F7.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of SLC25A35. Does perturbing ARHGAP22 lead to a significant change in SLC25A35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of SLC25A35. Does perturbing ARHGAP22 lead to a significant change in SLC25A35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Determine whether RP11-434H6.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Determine whether RP11-434H6.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-838N2.4. Does perturbing EIF2B2 lead to a significant change in RP11-838N2.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-838N2.4. Does perturbing EIF2B2 lead to a significant change in RP11-838N2.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3788,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and LINC01031 expression is quantified. Does this perturbation result in a significant change in LINC01031 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and LINC01031 expression is quantified. Does this perturbation result in a significant change in LINC01031 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1840,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Does this perturbation cause a significant change in OR2T6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Does this perturbation cause a significant change in OR2T6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of DUSP21. Does this perturbation cause a significant change in DUSP21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of DUSP21. Does this perturbation cause a significant change in DUSP21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ANKRD10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ANKRD10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3333,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and AP000688.8 expression is observed. Does this perturbation lead to a significant difference in AP000688.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and AP000688.8 expression is observed. Does this perturbation lead to a significant difference in AP000688.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EIF3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EIF3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1333,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and RCBTB2 expression is observed. Does this perturbation lead to a significant difference in RCBTB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and RCBTB2 expression is observed. Does this perturbation lead to a significant difference in RCBTB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1108,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of REST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of REST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of BOLA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of BOLA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of DNTTIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of DNTTIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of SLFNL1. Does perturbing SRPR lead to a significant change in SLFNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of SLFNL1. Does perturbing SRPR lead to a significant change in SLFNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in GALNT7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in GALNT7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ACE. Does perturbing FARSB lead to a significant change in ACE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ACE. Does perturbing FARSB lead to a significant change in ACE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of KCTD19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of KCTD19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of GOT1. Does this perturbation cause a significant change in GOT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of GOT1. Does this perturbation cause a significant change in GOT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3543,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and SEPT5 expression is observed. Does this perturbation lead to a significant difference in SEPT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and SEPT5 expression is observed. Does this perturbation lead to a significant difference in SEPT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in SPINK5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in SPINK5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1308,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ITGB2 expression. Decide whether this perturbation leads to a significant alteration in ITGB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ITGB2 expression. Decide whether this perturbation leads to a significant alteration in ITGB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1743,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and RPL39 expression is observed. Does this perturbation lead to a significant difference in RPL39 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and RPL39 expression is observed. Does this perturbation lead to a significant difference in RPL39 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of DYNC1H1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of DYNC1H1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of IRF7. Does perturbing IER3IP1 lead to a significant change in IRF7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of IRF7. Does perturbing IER3IP1 lead to a significant change in IRF7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of RP11-304M2.5. Does this perturbation cause a significant change in RP11-304M2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of RP11-304M2.5. Does this perturbation cause a significant change in RP11-304M2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4238,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor RP11-666A20.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-666A20.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor RP11-666A20.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-666A20.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
100,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Does this perturbation cause a significant change in NBEAL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Does this perturbation cause a significant change in NBEAL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4898,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor KIAA1731 expression. Decide whether this perturbation leads to a significant alteration in KIAA1731 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor KIAA1731 expression. Decide whether this perturbation leads to a significant alteration in KIAA1731 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2610,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2823,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PSMC1 expression is observed. Does this perturbation lead to a significant difference in PSMC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PSMC1 expression is observed. Does this perturbation lead to a significant difference in PSMC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in WDR72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in WDR72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of LTBP1. Does perturbing GMPPB lead to a significant change in LTBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of LTBP1. Does perturbing GMPPB lead to a significant change in LTBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of SRP72. Does this perturbation cause a significant change in SRP72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of SRP72. Does this perturbation cause a significant change in SRP72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
50,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Does this perturbation cause a significant change in C6orf48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Does this perturbation cause a significant change in C6orf48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3830,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Does this perturbation cause a significant change in PLA2G15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Does this perturbation cause a significant change in PLA2G15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2080,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Does this perturbation cause a significant change in PGM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Does this perturbation cause a significant change in PGM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of STC2. Does perturbing DDIT3 lead to a significant change in STC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of STC2. Does perturbing DDIT3 lead to a significant change in STC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of CDCA3. Does this perturbation cause a significant change in CDCA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of CDCA3. Does this perturbation cause a significant change in CDCA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of WHAMM. Does perturbing TIMM23 lead to a significant change in WHAMM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of WHAMM. Does perturbing TIMM23 lead to a significant change in WHAMM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of HAGH. Does this perturbation cause a significant change in HAGH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of HAGH. Does this perturbation cause a significant change in HAGH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3378,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor LIMS1 expression. Decide whether this perturbation leads to a significant alteration in LIMS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor LIMS1 expression. Decide whether this perturbation leads to a significant alteration in LIMS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
168,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RIMS3 expression. Decide whether this perturbation leads to a significant alteration in RIMS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RIMS3 expression. Decide whether this perturbation leads to a significant alteration in RIMS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and TLN1 expression is quantified. Does this perturbation result in a significant change in TLN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and TLN1 expression is quantified. Does this perturbation result in a significant change in TLN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of DSC2. Does this perturbation cause a significant change in DSC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of DSC2. Does this perturbation cause a significant change in DSC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TSPAN33 expression is measured. Determine whether TSPAN33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TSPAN33 expression is measured. Determine whether TSPAN33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1440,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Does this perturbation cause a significant change in AC079466.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Does this perturbation cause a significant change in AC079466.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in USP37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in USP37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1523,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZMYND8 expression is observed. Does this perturbation lead to a significant difference in ZMYND8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZMYND8 expression is observed. Does this perturbation lead to a significant difference in ZMYND8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ATP11B expression is measured. Determine whether ATP11B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ATP11B expression is measured. Determine whether ATP11B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1048,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HRK expression. Decide whether this perturbation leads to a significant alteration in HRK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HRK expression. Decide whether this perturbation leads to a significant alteration in HRK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
39,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and CASP4 expression is measured. Determine whether CASP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and CASP4 expression is measured. Determine whether CASP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5028,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor RP11-430H10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-430H10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor RP11-430H10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-430H10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ATP5EP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ATP5EP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
84,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of PHF3. Does this perturbation cause a significant change in PHF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of PHF3. Does this perturbation cause a significant change in PHF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ANKRD33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ANKRD33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3123,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of MANF. Does perturbing TTI2 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of MANF. Does perturbing TTI2 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
153,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and CTSF expression is observed. Does this perturbation lead to a significant difference in CTSF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and CTSF expression is observed. Does this perturbation lead to a significant difference in CTSF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of RP11-334C17.5. Does this perturbation cause a significant change in RP11-334C17.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of RP11-334C17.5. Does this perturbation cause a significant change in RP11-334C17.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in HM13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in HM13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and THBS1 expression is quantified. Does this perturbation result in a significant change in THBS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and THBS1 expression is quantified. Does this perturbation result in a significant change in THBS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PDE9A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PDE9A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2443,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP11-119J18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-119J18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP11-119J18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-119J18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
660,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Does this perturbation cause a significant change in PTBP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Does this perturbation cause a significant change in PTBP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2083,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and PGM3 expression is observed. Does this perturbation lead to a significant difference in PGM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and PGM3 expression is observed. Does this perturbation lead to a significant difference in PGM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4550,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Does this perturbation cause a significant change in CTC-550B14.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Does this perturbation cause a significant change in CTC-550B14.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2858,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor OXLD1 expression. Decide whether this perturbation leads to a significant alteration in OXLD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor OXLD1 expression. Decide whether this perturbation leads to a significant alteration in OXLD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in GMEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in GMEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5138,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CTC-308K20.1 expression. Decide whether this perturbation leads to a significant alteration in CTC-308K20.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CTC-308K20.1 expression. Decide whether this perturbation leads to a significant alteration in CTC-308K20.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Determine whether MTPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Determine whether MTPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of BOLA3. Does this perturbation cause a significant change in BOLA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of BOLA3. Does this perturbation cause a significant change in BOLA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of TOB2. Does this perturbation cause a significant change in TOB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of TOB2. Does this perturbation cause a significant change in TOB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1698,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in KDM1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in KDM1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3003,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Determine whether RP11-95O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Determine whether RP11-95O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
748,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ANXA4 expression. Decide whether this perturbation leads to a significant alteration in ANXA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ANXA4 expression. Decide whether this perturbation leads to a significant alteration in ANXA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and PAK1IP1 expression is measured. Determine whether PAK1IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and PAK1IP1 expression is measured. Determine whether PAK1IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of TACC3. Does perturbing CAD lead to a significant change in TACC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of TACC3. Does perturbing CAD lead to a significant change in TACC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EXOC3L2. Does perturbing PSMD4 lead to a significant change in EXOC3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EXOC3L2. Does perturbing PSMD4 lead to a significant change in EXOC3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
33,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and CASP4 expression is observed. Does this perturbation lead to a significant difference in CASP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and CASP4 expression is observed. Does this perturbation lead to a significant difference in CASP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and P4HB expression is measured. Determine whether P4HB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and P4HB expression is measured. Determine whether P4HB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Determine whether GSN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Determine whether GSN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of GRN. Does perturbing SRPRB lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of GRN. Does perturbing SRPRB lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PTPRC. Does perturbing DDIT3 lead to a significant change in PTPRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PTPRC. Does perturbing DDIT3 lead to a significant change in PTPRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
800,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Does this perturbation cause a significant change in COPB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Does this perturbation cause a significant change in COPB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3078,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PIF1 expression. Decide whether this perturbation leads to a significant alteration in PIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PIF1 expression. Decide whether this perturbation leads to a significant alteration in PIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of SERPINF2. Does perturbing SLC35B1 lead to a significant change in SERPINF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of SERPINF2. Does perturbing SLC35B1 lead to a significant change in SERPINF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2163,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and PDK2 expression is observed. Does this perturbation lead to a significant difference in PDK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and PDK2 expression is observed. Does this perturbation lead to a significant difference in PDK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in MEX3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in MEX3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of COPB1. Does this perturbation cause a significant change in COPB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of COPB1. Does this perturbation cause a significant change in COPB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of GS1-166A23.1. Does this perturbation cause a significant change in GS1-166A23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of GS1-166A23.1. Does this perturbation cause a significant change in GS1-166A23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NPDC1. Does this perturbation cause a significant change in NPDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NPDC1. Does this perturbation cause a significant change in NPDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and KANSL1L expression is quantified. Does this perturbation result in a significant change in KANSL1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and KANSL1L expression is quantified. Does this perturbation result in a significant change in KANSL1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and C3AR1 expression is quantified. Does this perturbation result in a significant change in C3AR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and C3AR1 expression is quantified. Does this perturbation result in a significant change in C3AR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1503,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1323,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NPDC1 expression is observed. Does this perturbation lead to a significant difference in NPDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NPDC1 expression is observed. Does this perturbation lead to a significant difference in NPDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4468,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor NAV1 expression. Decide whether this perturbation leads to a significant alteration in NAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor NAV1 expression. Decide whether this perturbation leads to a significant alteration in NAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of PPP4R2. Does perturbing HSPA9 lead to a significant change in PPP4R2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of PPP4R2. Does perturbing HSPA9 lead to a significant change in PPP4R2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ARHGAP11A. Does this perturbation cause a significant change in ARHGAP11A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ARHGAP11A. Does this perturbation cause a significant change in ARHGAP11A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDKN2C. Does this perturbation cause a significant change in CDKN2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDKN2C. Does this perturbation cause a significant change in CDKN2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
320,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Determine whether UBE2V1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Determine whether UBE2V1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of EXO1. Does this perturbation cause a significant change in EXO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of EXO1. Does this perturbation cause a significant change in EXO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of TIPARP. Does this perturbation cause a significant change in TIPARP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of TIPARP. Does this perturbation cause a significant change in TIPARP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of RP11-334C17.5. Does perturbing IDH3A lead to a significant change in RP11-334C17.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of RP11-334C17.5. Does perturbing IDH3A lead to a significant change in RP11-334C17.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of PIK3R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of PIK3R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of KCTD1. Does perturbing STT3A lead to a significant change in KCTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of KCTD1. Does perturbing STT3A lead to a significant change in KCTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in SAMM50 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in SAMM50 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
603,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and PBDC1 expression is observed. Does this perturbation lead to a significant difference in PBDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and PBDC1 expression is observed. Does this perturbation lead to a significant difference in PBDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and PIK3R1 expression is quantified. Does this perturbation result in a significant change in PIK3R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and PIK3R1 expression is quantified. Does this perturbation result in a significant change in PIK3R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
338,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2478,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in HIST1H2AC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in HIST1H2AC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3728,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ARHGAP11A expression. Decide whether this perturbation leads to a significant alteration in ARHGAP11A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ARHGAP11A expression. Decide whether this perturbation leads to a significant alteration in ARHGAP11A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2950,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Does this perturbation cause a significant change in ATP5EP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Does this perturbation cause a significant change in ATP5EP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of PARP11. Does perturbing TIMM44 lead to a significant change in PARP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of PARP11. Does perturbing TIMM44 lead to a significant change in PARP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RP11-16E12.1. Does this perturbation cause a significant change in RP11-16E12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RP11-16E12.1. Does this perturbation cause a significant change in RP11-16E12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of PRSS57. Does perturbing TMEM167A lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of PRSS57. Does perturbing TMEM167A lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2598,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor RP11-471M2.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-471M2.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor RP11-471M2.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-471M2.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ZNF789 expression is quantified. Does this perturbation result in a significant change in ZNF789 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ZNF789 expression is quantified. Does this perturbation result in a significant change in ZNF789 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in SERPING1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in SERPING1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of RCBTB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of RCBTB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Determine whether LDLR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Determine whether LDLR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Determine whether RP11-3D4.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Determine whether RP11-3D4.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HERC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HERC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in PLA2G15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in PLA2G15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Determine whether AFF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Determine whether AFF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of RP11-435O5.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of RP11-435O5.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in HLA-E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in HLA-E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Determine whether DUT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Determine whether DUT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of SEC23IP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of SEC23IP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4010,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Does this perturbation cause a significant change in DNMBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Does this perturbation cause a significant change in DNMBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3933,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ZXDA expression is observed. Does this perturbation lead to a significant difference in ZXDA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ZXDA expression is observed. Does this perturbation lead to a significant difference in ZXDA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of KCTD1. Does this perturbation cause a significant change in KCTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of KCTD1. Does this perturbation cause a significant change in KCTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2820,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Does this perturbation cause a significant change in PSMC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Does this perturbation cause a significant change in PSMC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and TRAPPC10 expression is quantified. Does this perturbation result in a significant change in TRAPPC10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and TRAPPC10 expression is quantified. Does this perturbation result in a significant change in TRAPPC10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Determine whether ASPM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Determine whether ASPM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5078,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ERP29 expression. Decide whether this perturbation leads to a significant alteration in ERP29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ERP29 expression. Decide whether this perturbation leads to a significant alteration in ERP29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in RP11-435O5.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in RP11-435O5.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3240,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Does this perturbation cause a significant change in SERPING1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Does this perturbation cause a significant change in SERPING1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CTC-308K20.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CTC-308K20.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2893,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of NFE2. Does perturbing DDIT3 lead to a significant change in NFE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of NFE2. Does perturbing DDIT3 lead to a significant change in NFE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Determine whether BIRC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Determine whether BIRC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5040,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Determine whether HAGH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Determine whether HAGH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in FOXO6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in FOXO6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4473,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and RP11-95O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-95O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and RP11-95O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-95O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of KANSL1L. Does perturbing HARS lead to a significant change in KANSL1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of KANSL1L. Does perturbing HARS lead to a significant change in KANSL1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
823,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and TMEM87B expression is observed. Does this perturbation lead to a significant difference in TMEM87B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and TMEM87B expression is observed. Does this perturbation lead to a significant difference in TMEM87B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2303,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SETD5-AS1 expression is quantified. Does this perturbation result in a significant change in SETD5-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SETD5-AS1 expression is quantified. Does this perturbation result in a significant change in SETD5-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of NCKAP1L. Does perturbing SRPR lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of NCKAP1L. Does perturbing SRPR lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA1432. Does perturbing PTDSS1 lead to a significant change in KIAA1432 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA1432. Does perturbing PTDSS1 lead to a significant change in KIAA1432 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DUT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DUT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3520,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Does this perturbation cause a significant change in TSPAN33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Does this perturbation cause a significant change in TSPAN33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4890,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Does this perturbation cause a significant change in KIAA1731 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Does this perturbation cause a significant change in KIAA1731 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4620,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Does this perturbation cause a significant change in KCNQ1OT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Does this perturbation cause a significant change in KCNQ1OT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2040,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Determine whether SP100 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Determine whether SP100 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PSMD14. Does this perturbation cause a significant change in PSMD14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PSMD14. Does this perturbation cause a significant change in PSMD14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of UQCRB. Does perturbing SLMO2 lead to a significant change in UQCRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of UQCRB. Does perturbing SLMO2 lead to a significant change in UQCRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2448,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP11-119J18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-119J18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP11-119J18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-119J18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Determine whether RP11-471M2.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Determine whether RP11-471M2.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PSMC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PSMC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of PKDCC. Does perturbing MTHFD1 lead to a significant change in PKDCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of PKDCC. Does perturbing MTHFD1 lead to a significant change in PKDCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Determine whether IFT27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Determine whether IFT27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of DNMBP. Does this perturbation cause a significant change in DNMBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of DNMBP. Does this perturbation cause a significant change in DNMBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
503,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PTPN11 expression is observed. Does this perturbation lead to a significant difference in PTPN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PTPN11 expression is observed. Does this perturbation lead to a significant difference in PTPN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1243,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and CYP17A1-AS1 expression is observed. Does this perturbation lead to a significant difference in CYP17A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and CYP17A1-AS1 expression is observed. Does this perturbation lead to a significant difference in CYP17A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4633,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and BOLA3 expression is observed. Does this perturbation lead to a significant difference in BOLA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and BOLA3 expression is observed. Does this perturbation lead to a significant difference in BOLA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of AKAP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of AKAP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in WHAMM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in WHAMM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ARSA expression is quantified. Does this perturbation result in a significant change in ARSA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ARSA expression is quantified. Does this perturbation result in a significant change in ARSA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3168,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MT2A expression. Decide whether this perturbation leads to a significant alteration in MT2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MT2A expression. Decide whether this perturbation leads to a significant alteration in MT2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2123,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and EBI3 expression is measured. Determine whether EBI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and EBI3 expression is measured. Determine whether EBI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3250,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC008074.3. Does perturbing CAD lead to a significant change in AC008074.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC008074.3. Does perturbing CAD lead to a significant change in AC008074.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is quantified. Does this perturbation result in a significant change in RP11-363D14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is quantified. Does this perturbation result in a significant change in RP11-363D14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RDH10. Does perturbing BHLHE40 lead to a significant change in RDH10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RDH10. Does perturbing BHLHE40 lead to a significant change in RDH10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NPDC1 expression is quantified. Does this perturbation result in a significant change in NPDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NPDC1 expression is quantified. Does this perturbation result in a significant change in NPDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2600,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Does this perturbation cause a significant change in CTCFL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Does this perturbation cause a significant change in CTCFL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of TSC22D4. Does this perturbation cause a significant change in TSC22D4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of TSC22D4. Does this perturbation cause a significant change in TSC22D4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
458,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor SLFNL1 expression. Decide whether this perturbation leads to a significant alteration in SLFNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor SLFNL1 expression. Decide whether this perturbation leads to a significant alteration in SLFNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
650,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Does this perturbation cause a significant change in POU2F2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Does this perturbation cause a significant change in POU2F2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA1432. Does this perturbation cause a significant change in KIAA1432 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA1432. Does this perturbation cause a significant change in KIAA1432 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1468,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Determine whether TSNAXIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Determine whether TSNAXIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and PHF21A expression is measured. Determine whether PHF21A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and PHF21A expression is measured. Determine whether PHF21A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1458,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor LRIF1 expression. Decide whether this perturbation leads to a significant alteration in LRIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor LRIF1 expression. Decide whether this perturbation leads to a significant alteration in LRIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of LINC00938. Does this perturbation cause a significant change in LINC00938 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of LINC00938. Does this perturbation cause a significant change in LINC00938 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of NFAT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of NFAT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in CD58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in CD58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in AC005540.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in AC005540.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-65L19.4. Does perturbing ZNF326 lead to a significant change in RP11-65L19.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-65L19.4. Does perturbing ZNF326 lead to a significant change in RP11-65L19.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TET1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TET1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4923,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1790,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Does this perturbation cause a significant change in PKDCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Does this perturbation cause a significant change in PKDCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
633,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and VPS41 expression is observed. Does this perturbation lead to a significant difference in VPS41 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and VPS41 expression is observed. Does this perturbation lead to a significant difference in VPS41 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Determine whether TSPAN33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Determine whether TSPAN33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and AC005540.3 expression is measured. Determine whether AC005540.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and AC005540.3 expression is measured. Determine whether AC005540.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in PPM1N expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in PPM1N expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in C10orf32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in C10orf32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of UBE2V1. Does perturbing SYVN1 lead to a significant change in UBE2V1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of UBE2V1. Does perturbing SYVN1 lead to a significant change in UBE2V1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1610,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Does this perturbation cause a significant change in RP11-81A22.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Does this perturbation cause a significant change in RP11-81A22.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of RP11-212I21.4. Does this perturbation cause a significant change in RP11-212I21.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of RP11-212I21.4. Does this perturbation cause a significant change in RP11-212I21.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3248,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor SERPING1 expression. Decide whether this perturbation leads to a significant alteration in SERPING1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor SERPING1 expression. Decide whether this perturbation leads to a significant alteration in SERPING1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3690,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Does this perturbation cause a significant change in TTC18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Does this perturbation cause a significant change in TTC18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4713,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and TAP1 expression is observed. Does this perturbation lead to a significant difference in TAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and TAP1 expression is observed. Does this perturbation lead to a significant difference in TAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of EP400 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of EP400 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4883,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and WARS expression is observed. Does this perturbation lead to a significant difference in WARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and WARS expression is observed. Does this perturbation lead to a significant difference in WARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in RCBTB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in RCBTB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4663,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and LINC01137 expression is observed. Does this perturbation lead to a significant difference in LINC01137 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and LINC01137 expression is observed. Does this perturbation lead to a significant difference in LINC01137 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5058,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor CFH expression. Decide whether this perturbation leads to a significant alteration in CFH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor CFH expression. Decide whether this perturbation leads to a significant alteration in CFH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of IL32. Does perturbing YIPF5 lead to a significant change in IL32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of IL32. Does perturbing YIPF5 lead to a significant change in IL32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2518,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor RBM12B-AS1 expression. Decide whether this perturbation leads to a significant alteration in RBM12B-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor RBM12B-AS1 expression. Decide whether this perturbation leads to a significant alteration in RBM12B-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of RP11-95O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of RP11-95O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and SEC23IP expression is quantified. Does this perturbation result in a significant change in SEC23IP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and SEC23IP expression is quantified. Does this perturbation result in a significant change in SEC23IP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of PDRG1. Does this perturbation cause a significant change in PDRG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of PDRG1. Does this perturbation cause a significant change in PDRG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1730,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Does this perturbation cause a significant change in USP37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Does this perturbation cause a significant change in USP37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CTBS. Does this perturbation cause a significant change in CTBS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CTBS. Does this perturbation cause a significant change in CTBS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1220,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Does this perturbation cause a significant change in UBE3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Does this perturbation cause a significant change in UBE3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HRK expression is measured. Determine whether HRK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HRK expression is measured. Determine whether HRK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Determine whether TMOD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Determine whether TMOD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4588,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RASGRP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RASGRP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in CELF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in CELF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Determine whether NOSTRIN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Determine whether NOSTRIN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3988,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of CTD-2587M2.1. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of CTD-2587M2.1. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3888,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor RP11-573D15.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor RP11-573D15.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2073,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in DKFZP779L1853 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in DKFZP779L1853 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2838,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor EXO1 expression. Decide whether this perturbation leads to a significant alteration in EXO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor EXO1 expression. Decide whether this perturbation leads to a significant alteration in EXO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in DNASE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in DNASE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TRIM38 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TRIM38 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2240,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Does this perturbation cause a significant change in AMOTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Does this perturbation cause a significant change in AMOTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Determine whether RP11-863K10.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Determine whether RP11-863K10.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3740,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Does this perturbation cause a significant change in KIAA0922 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Does this perturbation cause a significant change in KIAA0922 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is quantified. Does this perturbation result in a significant change in RP11-304M2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is quantified. Does this perturbation result in a significant change in RP11-304M2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CTC-308K20.1. Does this perturbation cause a significant change in CTC-308K20.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CTC-308K20.1. Does this perturbation cause a significant change in CTC-308K20.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and PBDC1 expression is quantified. Does this perturbation result in a significant change in PBDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and PBDC1 expression is quantified. Does this perturbation result in a significant change in PBDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of UHMK1. Does perturbing P4HB lead to a significant change in UHMK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of UHMK1. Does perturbing P4HB lead to a significant change in UHMK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
908,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor PRRC2B expression. Decide whether this perturbation leads to a significant alteration in PRRC2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor PRRC2B expression. Decide whether this perturbation leads to a significant alteration in PRRC2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1413,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NOXA1 expression is observed. Does this perturbation lead to a significant difference in NOXA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NOXA1 expression is observed. Does this perturbation lead to a significant difference in NOXA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and FCGRT expression is quantified. Does this perturbation result in a significant change in FCGRT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and FCGRT expression is quantified. Does this perturbation result in a significant change in FCGRT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of DNMBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of DNMBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4438,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and GPR146 expression is measured. Determine whether GPR146 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and GPR146 expression is measured. Determine whether GPR146 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of SNHG10. Does perturbing CAD lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of SNHG10. Does perturbing CAD lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3820,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Does this perturbation cause a significant change in OBSCN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Does this perturbation cause a significant change in OBSCN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of HIST1H2BC. Does perturbing DNAJC19 lead to a significant change in HIST1H2BC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of HIST1H2BC. Does perturbing DNAJC19 lead to a significant change in HIST1H2BC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in LINC01137 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in LINC01137 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MT2A expression is measured. Determine whether MT2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MT2A expression is measured. Determine whether MT2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of DKFZP779L1853. Does perturbing HSPA9 lead to a significant change in DKFZP779L1853 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of DKFZP779L1853. Does perturbing HSPA9 lead to a significant change in DKFZP779L1853 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and WHSC1 expression is quantified. Does this perturbation result in a significant change in WHSC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and WHSC1 expression is quantified. Does this perturbation result in a significant change in WHSC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and PSORS1C1 expression is quantified. Does this perturbation result in a significant change in PSORS1C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and PSORS1C1 expression is quantified. Does this perturbation result in a significant change in PSORS1C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and HLTF expression is quantified. Does this perturbation result in a significant change in HLTF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and HLTF expression is quantified. Does this perturbation result in a significant change in HLTF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
133,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TET1 expression is observed. Does this perturbation lead to a significant difference in TET1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TET1 expression is observed. Does this perturbation lead to a significant difference in TET1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
263,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DOK3 expression is observed. Does this perturbation lead to a significant difference in DOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DOK3 expression is observed. Does this perturbation lead to a significant difference in DOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SETD5-AS1. Does perturbing UFL1 lead to a significant change in SETD5-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SETD5-AS1. Does perturbing UFL1 lead to a significant change in SETD5-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Determine whether KCNE3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Determine whether KCNE3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1193,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and RP11-435O5.4 expression is observed. Does this perturbation lead to a significant difference in RP11-435O5.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and RP11-435O5.4 expression is observed. Does this perturbation lead to a significant difference in RP11-435O5.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of JUND indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of JUND indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and USP34 expression is quantified. Does this perturbation result in a significant change in USP34 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and USP34 expression is quantified. Does this perturbation result in a significant change in USP34 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
628,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor SAMM50 expression. Decide whether this perturbation leads to a significant alteration in SAMM50 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor SAMM50 expression. Decide whether this perturbation leads to a significant alteration in SAMM50 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA1432 expression is measured. Determine whether KIAA1432 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA1432 expression is measured. Determine whether KIAA1432 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CTD-2521M24.9. Does perturbing ASCC3 lead to a significant change in CTD-2521M24.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CTD-2521M24.9. Does perturbing ASCC3 lead to a significant change in CTD-2521M24.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ANKRD11. Does this perturbation cause a significant change in ANKRD11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ANKRD11. Does this perturbation cause a significant change in ANKRD11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1470,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Does this perturbation cause a significant change in ARHGAP30 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Does this perturbation cause a significant change in ARHGAP30 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1270,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of AP000688.8. Does perturbing PSMD4 lead to a significant change in AP000688.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of AP000688.8. Does perturbing PSMD4 lead to a significant change in AP000688.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and FAM212A expression is quantified. Does this perturbation result in a significant change in FAM212A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and FAM212A expression is quantified. Does this perturbation result in a significant change in FAM212A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ZNF341 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ZNF341 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1368,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ZNF678 expression. Decide whether this perturbation leads to a significant alteration in ZNF678 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ZNF678 expression. Decide whether this perturbation leads to a significant alteration in ZNF678 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5000,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of HPCAL1. Does this perturbation cause a significant change in HPCAL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of HPCAL1. Does this perturbation cause a significant change in HPCAL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of SERPING1. Does this perturbation cause a significant change in SERPING1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of SERPING1. Does this perturbation cause a significant change in SERPING1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ESCO1. Does this perturbation cause a significant change in ESCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ESCO1. Does this perturbation cause a significant change in ESCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1563,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and DOCK8 expression is observed. Does this perturbation lead to a significant difference in DOCK8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and DOCK8 expression is observed. Does this perturbation lead to a significant difference in DOCK8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and DNTTIP2 expression is quantified. Does this perturbation result in a significant change in DNTTIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and DNTTIP2 expression is quantified. Does this perturbation result in a significant change in DNTTIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IFT27. Does this perturbation cause a significant change in IFT27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IFT27. Does this perturbation cause a significant change in IFT27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and LINC00862 expression is measured. Determine whether LINC00862 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and LINC00862 expression is measured. Determine whether LINC00862 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5110,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Does this perturbation cause a significant change in GATA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Does this perturbation cause a significant change in GATA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3783,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and LINC00657 expression is quantified. Does this perturbation result in a significant change in LINC00657 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and LINC00657 expression is quantified. Does this perturbation result in a significant change in LINC00657 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and RSL24D1 expression is quantified. Does this perturbation result in a significant change in RSL24D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and RSL24D1 expression is quantified. Does this perturbation result in a significant change in RSL24D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ROCK1. Does perturbing SPCS2 lead to a significant change in ROCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ROCK1. Does perturbing SPCS2 lead to a significant change in ROCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4483,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1913,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and CTD-2587M2.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2587M2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and CTD-2587M2.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2587M2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2198,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor SLC26A1 expression. Decide whether this perturbation leads to a significant alteration in SLC26A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor SLC26A1 expression. Decide whether this perturbation leads to a significant alteration in SLC26A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EP300. Does perturbing SYVN1 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EP300. Does perturbing SYVN1 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and SERPINH1 expression is quantified. Does this perturbation result in a significant change in SERPINH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and SERPINH1 expression is quantified. Does this perturbation result in a significant change in SERPINH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of AC012594.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of AC012594.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of C12orf23. Does perturbing MTHFD1 lead to a significant change in C12orf23 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of C12orf23. Does perturbing MTHFD1 lead to a significant change in C12orf23 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and HERPUD1 expression is measured. Determine whether HERPUD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and HERPUD1 expression is measured. Determine whether HERPUD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3710,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Does this perturbation cause a significant change in C17orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Does this perturbation cause a significant change in C17orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1410,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Does this perturbation cause a significant change in NOXA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Does this perturbation cause a significant change in NOXA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-789C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-789C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ARHGAP30 expression is measured. Determine whether ARHGAP30 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ARHGAP30 expression is measured. Determine whether ARHGAP30 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
980,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Does this perturbation cause a significant change in TOB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Does this perturbation cause a significant change in TOB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of NPAT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of NPAT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of KLF3. Does this perturbation cause a significant change in KLF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of KLF3. Does this perturbation cause a significant change in KLF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
318,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of WDR3. Does this perturbation cause a significant change in WDR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of WDR3. Does this perturbation cause a significant change in WDR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1200,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Does this perturbation cause a significant change in GMEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Does this perturbation cause a significant change in GMEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of SERPINF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of SERPINF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2233,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and FAM212A expression is observed. Does this perturbation lead to a significant difference in FAM212A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and FAM212A expression is observed. Does this perturbation lead to a significant difference in FAM212A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
343,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and MS4A6E expression is observed. Does this perturbation lead to a significant difference in MS4A6E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and MS4A6E expression is observed. Does this perturbation lead to a significant difference in MS4A6E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in GDF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in GDF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2810,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Does this perturbation cause a significant change in CDKN2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Does this perturbation cause a significant change in CDKN2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and CDRT4 expression is measured. Determine whether CDRT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and CDRT4 expression is measured. Determine whether CDRT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CPQ expression is quantified. Does this perturbation result in a significant change in CPQ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CPQ expression is quantified. Does this perturbation result in a significant change in CPQ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1813,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and NFAT5 expression is observed. Does this perturbation lead to a significant difference in NFAT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and NFAT5 expression is observed. Does this perturbation lead to a significant difference in NFAT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1363,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ZNF678 expression is observed. Does this perturbation lead to a significant difference in ZNF678 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ZNF678 expression is observed. Does this perturbation lead to a significant difference in ZNF678 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of RP11-247A12.2. Does perturbing ATP5B lead to a significant change in RP11-247A12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of RP11-247A12.2. Does perturbing ATP5B lead to a significant change in RP11-247A12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HIST1H3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HIST1H3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of SHOX2. Does perturbing IDH3A lead to a significant change in SHOX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of SHOX2. Does perturbing IDH3A lead to a significant change in SHOX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
93,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-141B14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-141B14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-141B14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-141B14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1348,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NSD1 expression. Decide whether this perturbation leads to a significant alteration in NSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NSD1 expression. Decide whether this perturbation leads to a significant alteration in NSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SMIM14 expression is measured. Determine whether SMIM14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SMIM14 expression is measured. Determine whether SMIM14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of PBDC1. Does this perturbation cause a significant change in PBDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of PBDC1. Does this perturbation cause a significant change in PBDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is measured. Determine whether RP11-138C9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is measured. Determine whether RP11-138C9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and KCNE3 expression is quantified. Does this perturbation result in a significant change in KCNE3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and KCNE3 expression is quantified. Does this perturbation result in a significant change in KCNE3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4690,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Does this perturbation cause a significant change in ANKRD11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Does this perturbation cause a significant change in ANKRD11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of GALNT7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of GALNT7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3290,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Does this perturbation cause a significant change in GS1-166A23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Does this perturbation cause a significant change in GS1-166A23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CHST12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CHST12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is measured. Determine whether RP11-334C17.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is measured. Determine whether RP11-334C17.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of IL18R1. Does perturbing SEC61A1 lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of IL18R1. Does perturbing SEC61A1 lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-227G15.8 expression is quantified. Does this perturbation result in a significant change in RP11-227G15.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-227G15.8 expression is quantified. Does this perturbation result in a significant change in RP11-227G15.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of C6orf120. Does this perturbation cause a significant change in C6orf120 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of C6orf120. Does this perturbation cause a significant change in C6orf120 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in KLF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in KLF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and GMEB1 expression is measured. Determine whether GMEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and GMEB1 expression is measured. Determine whether GMEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in EBI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in EBI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1170,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Determine whether BACH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Determine whether BACH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
410,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Does this perturbation cause a significant change in SPINK5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Does this perturbation cause a significant change in SPINK5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and NFAT5 expression is measured. Determine whether NFAT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and NFAT5 expression is measured. Determine whether NFAT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is measured. Determine whether HIST1H2AC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is measured. Determine whether HIST1H2AC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of LBX1. Does this perturbation cause a significant change in LBX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of LBX1. Does this perturbation cause a significant change in LBX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2613,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of RP11-435O5.4. Does this perturbation cause a significant change in RP11-435O5.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of RP11-435O5.4. Does this perturbation cause a significant change in RP11-435O5.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1640,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Does this perturbation cause a significant change in SERPINH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Does this perturbation cause a significant change in SERPINH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and PITPNB expression is measured. Determine whether PITPNB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and PITPNB expression is measured. Determine whether PITPNB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and TSC22D4 expression is measured. Determine whether TSC22D4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and TSC22D4 expression is measured. Determine whether TSC22D4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
398,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor GDF11 expression. Decide whether this perturbation leads to a significant alteration in GDF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor GDF11 expression. Decide whether this perturbation leads to a significant alteration in GDF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and SPCS2 expression is measured. Determine whether SPCS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and SPCS2 expression is measured. Determine whether SPCS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of RGS20. Does perturbing ARHGAP22 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of RGS20. Does perturbing ARHGAP22 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Determine whether JARID2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Determine whether JARID2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of FAM212A. Does this perturbation cause a significant change in FAM212A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of FAM212A. Does this perturbation cause a significant change in FAM212A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Determine whether STARD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Determine whether STARD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4513,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and HM13 expression is observed. Does this perturbation lead to a significant difference in HM13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and HM13 expression is observed. Does this perturbation lead to a significant difference in HM13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3548,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor SEPT5 expression. Decide whether this perturbation leads to a significant alteration in SEPT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor SEPT5 expression. Decide whether this perturbation leads to a significant alteration in SEPT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4590,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Does this perturbation cause a significant change in LINC00862 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Does this perturbation cause a significant change in LINC00862 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and GSN expression is quantified. Does this perturbation result in a significant change in GSN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and GSN expression is quantified. Does this perturbation result in a significant change in GSN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
598,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ZNF789 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ZNF789 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2933,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-227G15.8 expression is observed. Does this perturbation lead to a significant difference in RP11-227G15.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-227G15.8 expression is observed. Does this perturbation lead to a significant difference in RP11-227G15.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EPS15. Does this perturbation cause a significant change in EPS15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EPS15. Does this perturbation cause a significant change in EPS15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3880,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Does this perturbation cause a significant change in RP11-573D15.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Does this perturbation cause a significant change in RP11-573D15.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GLG1. Does this perturbation cause a significant change in GLG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GLG1. Does this perturbation cause a significant change in GLG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TMEM60. Does perturbing SCYL1 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TMEM60. Does perturbing SCYL1 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is measured. Determine whether RP11-304M2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is measured. Determine whether RP11-304M2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is measured. Determine whether RP11-640M9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is measured. Determine whether RP11-640M9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PTPRC expression is quantified. Does this perturbation result in a significant change in PTPRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PTPRC expression is quantified. Does this perturbation result in a significant change in PTPRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PTAR1. Does this perturbation cause a significant change in PTAR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PTAR1. Does this perturbation cause a significant change in PTAR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1123,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-640M9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-640M9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-640M9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-640M9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HIST1H3D. Does perturbing DARS lead to a significant change in HIST1H3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HIST1H3D. Does perturbing DARS lead to a significant change in HIST1H3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ARHGAP30. Does this perturbation cause a significant change in ARHGAP30 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ARHGAP30. Does this perturbation cause a significant change in ARHGAP30 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in CDCA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in CDCA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Determine whether TIPARP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Determine whether TIPARP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of PKDCC. Does this perturbation cause a significant change in PKDCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of PKDCC. Does this perturbation cause a significant change in PKDCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
863,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ESCO1 expression is observed. Does this perturbation lead to a significant difference in ESCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ESCO1 expression is observed. Does this perturbation lead to a significant difference in ESCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of KCNJ13. Does this perturbation cause a significant change in KCNJ13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of KCNJ13. Does this perturbation cause a significant change in KCNJ13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of FOXO6. Does this perturbation cause a significant change in FOXO6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of FOXO6. Does this perturbation cause a significant change in FOXO6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3403,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and C3AR1 expression is observed. Does this perturbation lead to a significant difference in C3AR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and C3AR1 expression is observed. Does this perturbation lead to a significant difference in C3AR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2903,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and VAMP2 expression is observed. Does this perturbation lead to a significant difference in VAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and VAMP2 expression is observed. Does this perturbation lead to a significant difference in VAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2213,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and GDF11 expression is quantified. Does this perturbation result in a significant change in GDF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and GDF11 expression is quantified. Does this perturbation result in a significant change in GDF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2153,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SNRNP25 expression is observed. Does this perturbation lead to a significant difference in SNRNP25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SNRNP25 expression is observed. Does this perturbation lead to a significant difference in SNRNP25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Determine whether RP11-435O5.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Determine whether RP11-435O5.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DUT expression is quantified. Does this perturbation result in a significant change in DUT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DUT expression is quantified. Does this perturbation result in a significant change in DUT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in RP11-430H10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in RP11-430H10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of SMCO1. Does perturbing PPWD1 lead to a significant change in SMCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of SMCO1. Does perturbing PPWD1 lead to a significant change in SMCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GLG1 expression is quantified. Does this perturbation result in a significant change in GLG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GLG1 expression is quantified. Does this perturbation result in a significant change in GLG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and RTN2 expression is quantified. Does this perturbation result in a significant change in RTN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and RTN2 expression is quantified. Does this perturbation result in a significant change in RTN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4860,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Does this perturbation cause a significant change in NAV2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Does this perturbation cause a significant change in NAV2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3628,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and PHF21A expression is quantified. Does this perturbation result in a significant change in PHF21A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and PHF21A expression is quantified. Does this perturbation result in a significant change in PHF21A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of HIST1H2AM. Does perturbing MRPL39 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of HIST1H2AM. Does perturbing MRPL39 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of RP11-212I21.4. Does perturbing GNPNAT1 lead to a significant change in RP11-212I21.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of RP11-212I21.4. Does perturbing GNPNAT1 lead to a significant change in RP11-212I21.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4310,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Does this perturbation cause a significant change in MED13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Does this perturbation cause a significant change in MED13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Determine whether RP11-666A20.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Determine whether RP11-666A20.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA0922 expression is measured. Determine whether KIAA0922 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA0922 expression is measured. Determine whether KIAA0922 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4360,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Does this perturbation cause a significant change in USP34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Does this perturbation cause a significant change in USP34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
83,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and PHF3 expression is observed. Does this perturbation lead to a significant difference in PHF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and PHF3 expression is observed. Does this perturbation lead to a significant difference in PHF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ZNF341 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ZNF341 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2033,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and RP11-212I21.4 expression is observed. Does this perturbation lead to a significant difference in RP11-212I21.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and RP11-212I21.4 expression is observed. Does this perturbation lead to a significant difference in RP11-212I21.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Determine whether SEC23IP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Determine whether SEC23IP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3440,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Does this perturbation cause a significant change in CCDC69 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Does this perturbation cause a significant change in CCDC69 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ROBO1. Does perturbing SLC35B1 lead to a significant change in ROBO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ROBO1. Does perturbing SLC35B1 lead to a significant change in ROBO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4330,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Does this perturbation cause a significant change in GRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Does this perturbation cause a significant change in GRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Determine whether SETD5-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Determine whether SETD5-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of GPR146. Does perturbing SPCS3 lead to a significant change in GPR146 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of GPR146. Does perturbing SPCS3 lead to a significant change in GPR146 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4320,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Does this perturbation cause a significant change in NOSTRIN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Does this perturbation cause a significant change in NOSTRIN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
798,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor REST expression. Decide whether this perturbation leads to a significant alteration in REST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor REST expression. Decide whether this perturbation leads to a significant alteration in REST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CD83 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CD83 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and HLA-E expression is measured. Determine whether HLA-E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and HLA-E expression is measured. Determine whether HLA-E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4718,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor TAP1 expression. Decide whether this perturbation leads to a significant alteration in TAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor TAP1 expression. Decide whether this perturbation leads to a significant alteration in TAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3928,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor PPM1N expression. Decide whether this perturbation leads to a significant alteration in PPM1N expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor PPM1N expression. Decide whether this perturbation leads to a significant alteration in PPM1N expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Determine whether EPS15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Determine whether EPS15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and RAD51AP1 expression is quantified. Does this perturbation result in a significant change in RAD51AP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and RAD51AP1 expression is quantified. Does this perturbation result in a significant change in RAD51AP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in WDR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in WDR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PSMD14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PSMD14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3513,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3063,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PHF19 expression is observed. Does this perturbation lead to a significant difference in PHF19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PHF19 expression is observed. Does this perturbation lead to a significant difference in PHF19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IDH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IDH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NOXA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NOXA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and CDRT4 expression is quantified. Does this perturbation result in a significant change in CDRT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and CDRT4 expression is quantified. Does this perturbation result in a significant change in CDRT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ATP6V1B2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ATP6V1B2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2898,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of TRAPPC10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of TRAPPC10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in RP11-445H22.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in RP11-445H22.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and PLA2G15 expression is quantified. Does this perturbation result in a significant change in PLA2G15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and PLA2G15 expression is quantified. Does this perturbation result in a significant change in PLA2G15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of PITPNB. Does this perturbation cause a significant change in PITPNB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of PITPNB. Does this perturbation cause a significant change in PITPNB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IDH3A. Does this perturbation cause a significant change in IDH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IDH3A. Does this perturbation cause a significant change in IDH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of CYP17A1-AS1. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of CYP17A1-AS1. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is quantified. Does this perturbation result in a significant change in RP11-65L19.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is quantified. Does this perturbation result in a significant change in RP11-65L19.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Determine whether HIST1H2BC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Determine whether HIST1H2BC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3900,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and P4HB expression is quantified. Does this perturbation result in a significant change in P4HB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and P4HB expression is quantified. Does this perturbation result in a significant change in P4HB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of TFPI. Does perturbing SLC35B1 lead to a significant change in TFPI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of TFPI. Does perturbing SLC35B1 lead to a significant change in TFPI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
893,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and APOL4 expression is observed. Does this perturbation lead to a significant difference in APOL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and APOL4 expression is observed. Does this perturbation lead to a significant difference in APOL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2973,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and HPCAL1 expression is observed. Does this perturbation lead to a significant difference in HPCAL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and HPCAL1 expression is observed. Does this perturbation lead to a significant difference in HPCAL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1340,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Does this perturbation cause a significant change in NSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Does this perturbation cause a significant change in NSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Determine whether CENPF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Determine whether CENPF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of DOCK11. Does this perturbation cause a significant change in DOCK11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of DOCK11. Does this perturbation cause a significant change in DOCK11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Determine whether ATP6V1B2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Determine whether ATP6V1B2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4750,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Determine whether DST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Determine whether DST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SNRNP25. Does this perturbation cause a significant change in SNRNP25 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SNRNP25. Does this perturbation cause a significant change in SNRNP25 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Determine whether RTN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Determine whether RTN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4558,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CTC-550B14.7 expression. Decide whether this perturbation leads to a significant alteration in CTC-550B14.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CTC-550B14.7 expression. Decide whether this perturbation leads to a significant alteration in CTC-550B14.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3538,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor FCGRT expression. Decide whether this perturbation leads to a significant alteration in FCGRT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor FCGRT expression. Decide whether this perturbation leads to a significant alteration in FCGRT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PIF1. Does perturbing SARS lead to a significant change in PIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PIF1. Does perturbing SARS lead to a significant change in PIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-499F3.2. Does perturbing TARS lead to a significant change in RP11-499F3.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-499F3.2. Does perturbing TARS lead to a significant change in RP11-499F3.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CCDC69 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CCDC69 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ATP11B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ATP11B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and RP11-573D15.2 expression is measured. Determine whether RP11-573D15.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and RP11-573D15.2 expression is measured. Determine whether RP11-573D15.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HMGCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HMGCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1050,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Does this perturbation cause a significant change in RP11-38P22.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Does this perturbation cause a significant change in RP11-38P22.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
998,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor SHOX2 expression. Decide whether this perturbation leads to a significant alteration in SHOX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor SHOX2 expression. Decide whether this perturbation leads to a significant alteration in SHOX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
290,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Does this perturbation cause a significant change in ATP11B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Does this perturbation cause a significant change in ATP11B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-838N2.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-838N2.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in RSL24D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in RSL24D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of PGM3. Does this perturbation cause a significant change in PGM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of PGM3. Does this perturbation cause a significant change in PGM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CHD3 expression is measured. Determine whether CHD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CHD3 expression is measured. Determine whether CHD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ZEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ZEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1063,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and KHDC1L expression is observed. Does this perturbation lead to a significant difference in KHDC1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and KHDC1L expression is observed. Does this perturbation lead to a significant difference in KHDC1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2340,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Does this perturbation cause a significant change in C19orf59 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Does this perturbation cause a significant change in C19orf59 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of SNHG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of SNHG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of UFD1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of UFD1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
438,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CLINT1 expression. Decide whether this perturbation leads to a significant alteration in CLINT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CLINT1 expression. Decide whether this perturbation leads to a significant alteration in CLINT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
443,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of JUND. Does perturbing DAD1 lead to a significant change in JUND expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of JUND. Does perturbing DAD1 lead to a significant change in JUND expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and BOLA3 expression is measured. Determine whether BOLA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and BOLA3 expression is measured. Determine whether BOLA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ATAD2B. Does perturbing FECH lead to a significant change in ATAD2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ATAD2B. Does perturbing FECH lead to a significant change in ATAD2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of GATA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of GATA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CTSV expression is measured. Determine whether CTSV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CTSV expression is measured. Determine whether CTSV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2670,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Does this perturbation cause a significant change in CTSV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Does this perturbation cause a significant change in CTSV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3903,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and HOTAIRM1 expression is measured. Determine whether HOTAIRM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and HOTAIRM1 expression is measured. Determine whether HOTAIRM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4868,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor NAV2 expression. Decide whether this perturbation leads to a significant alteration in NAV2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor NAV2 expression. Decide whether this perturbation leads to a significant alteration in NAV2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of RNF139-AS1. Does perturbing FARSB lead to a significant change in RNF139-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of RNF139-AS1. Does perturbing FARSB lead to a significant change in RNF139-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and OR2T6 expression is quantified. Does this perturbation result in a significant change in OR2T6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and OR2T6 expression is quantified. Does this perturbation result in a significant change in OR2T6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of RCBTB2. Does this perturbation cause a significant change in RCBTB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of RCBTB2. Does this perturbation cause a significant change in RCBTB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of LINC01137. Does perturbing EIF2B3 lead to a significant change in LINC01137 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of LINC01137. Does perturbing EIF2B3 lead to a significant change in LINC01137 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in MYH7B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in MYH7B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA0922. Does perturbing PTDSS1 lead to a significant change in KIAA0922 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA0922. Does perturbing PTDSS1 lead to a significant change in KIAA0922 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AC007038.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AC007038.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of FOXO6. Does perturbing UFM1 lead to a significant change in FOXO6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of FOXO6. Does perturbing UFM1 lead to a significant change in FOXO6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of NBEAL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of NBEAL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1510,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Does this perturbation cause a significant change in TMOD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Does this perturbation cause a significant change in TMOD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and SLFNL1 expression is measured. Determine whether SLFNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and SLFNL1 expression is measured. Determine whether SLFNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is measured. Determine whether RP13-216E22.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is measured. Determine whether RP13-216E22.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2440,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Does this perturbation cause a significant change in RP11-119J18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Does this perturbation cause a significant change in RP11-119J18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4683,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and EXO1 expression is quantified. Does this perturbation result in a significant change in EXO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and EXO1 expression is quantified. Does this perturbation result in a significant change in EXO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of C6orf120. Does perturbing NEDD8 lead to a significant change in C6orf120 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of C6orf120. Does perturbing NEDD8 lead to a significant change in C6orf120 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PHF19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PHF19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
288,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor CDRT4 expression. Decide whether this perturbation leads to a significant alteration in CDRT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor CDRT4 expression. Decide whether this perturbation leads to a significant alteration in CDRT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PDE4D expression is measured. Determine whether PDE4D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PDE4D expression is measured. Determine whether PDE4D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4603,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and STARD9 expression is observed. Does this perturbation lead to a significant difference in STARD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and STARD9 expression is observed. Does this perturbation lead to a significant difference in STARD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of NBEAL2. Does perturbing ZNF326 lead to a significant change in NBEAL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of NBEAL2. Does perturbing ZNF326 lead to a significant change in NBEAL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4500,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Does this perturbation cause a significant change in BIRC5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Does this perturbation cause a significant change in BIRC5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of UFD1L. Does perturbing GBF1 lead to a significant change in UFD1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of UFD1L. Does perturbing GBF1 lead to a significant change in UFD1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and SLC27A2 expression is measured. Determine whether SLC27A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and SLC27A2 expression is measured. Determine whether SLC27A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2070,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2698,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CD83 expression. Decide whether this perturbation leads to a significant alteration in CD83 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CD83 expression. Decide whether this perturbation leads to a significant alteration in CD83 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Determine whether LBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Determine whether LBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in NXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in NXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and CD58 expression is measured. Determine whether CD58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and CD58 expression is measured. Determine whether CD58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in STC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in STC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2038,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor RP11-212I21.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-212I21.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor RP11-212I21.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-212I21.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of DST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of DST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ZCCHC11 expression is measured. Determine whether ZCCHC11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ZCCHC11 expression is measured. Determine whether ZCCHC11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2193,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and SLC26A1 expression is observed. Does this perturbation lead to a significant difference in SLC26A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and SLC26A1 expression is observed. Does this perturbation lead to a significant difference in SLC26A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2543,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ZP3 expression is observed. Does this perturbation lead to a significant difference in ZP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ZP3 expression is observed. Does this perturbation lead to a significant difference in ZP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
923,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3058,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-363D14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-363D14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-363D14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-363D14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1880,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of PGM3. Does perturbing TTI2 lead to a significant change in PGM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of PGM3. Does perturbing TTI2 lead to a significant change in PGM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of PIK3R1. Does perturbing SPCS2 lead to a significant change in PIK3R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of PIK3R1. Does perturbing SPCS2 lead to a significant change in PIK3R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3203,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4538,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor RP11-304M2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-304M2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor RP11-304M2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-304M2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PTPN11. Does perturbing IER3IP1 lead to a significant change in PTPN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PTPN11. Does perturbing IER3IP1 lead to a significant change in PTPN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NUF2 expression is measured. Determine whether NUF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NUF2 expression is measured. Determine whether NUF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3553,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and CCRL2 expression is observed. Does this perturbation lead to a significant difference in CCRL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and CCRL2 expression is observed. Does this perturbation lead to a significant difference in CCRL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3023,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of TGOLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of TGOLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3170,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Does this perturbation cause a significant change in MLEC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Does this perturbation cause a significant change in MLEC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4033,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and NTRK1 expression is observed. Does this perturbation lead to a significant difference in NTRK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and NTRK1 expression is observed. Does this perturbation lead to a significant difference in NTRK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1328,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NPDC1 expression. Decide whether this perturbation leads to a significant alteration in NPDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NPDC1 expression. Decide whether this perturbation leads to a significant alteration in NPDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of DDX3X. Does perturbing SOCS1 lead to a significant change in DDX3X expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of DDX3X. Does perturbing SOCS1 lead to a significant change in DDX3X expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ESCO1. Does perturbing AMIGO3 lead to a significant change in ESCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ESCO1. Does perturbing AMIGO3 lead to a significant change in ESCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1360,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Does this perturbation cause a significant change in ZNF678 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Does this perturbation cause a significant change in ZNF678 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in RP11-132A1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in RP11-132A1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1010,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Does this perturbation cause a significant change in KCNE3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Does this perturbation cause a significant change in KCNE3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PTAR1. Does perturbing SLC39A7 lead to a significant change in PTAR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PTAR1. Does perturbing SLC39A7 lead to a significant change in PTAR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of GALNT7. Does perturbing FECH lead to a significant change in GALNT7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of GALNT7. Does perturbing FECH lead to a significant change in GALNT7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IFNGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IFNGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Determine whether CASP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Determine whether CASP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PAXBP1 expression is quantified. Does this perturbation result in a significant change in PAXBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PAXBP1 expression is quantified. Does this perturbation result in a significant change in PAXBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
378,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HMGCS1 expression. Decide whether this perturbation leads to a significant alteration in HMGCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HMGCS1 expression. Decide whether this perturbation leads to a significant alteration in HMGCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Determine whether DOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Determine whether DOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in TSC22D4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in TSC22D4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3320,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Does this perturbation cause a significant change in NPAT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Does this perturbation cause a significant change in NPAT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
328,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PDE3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PDE3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and NAV2 expression is measured. Determine whether NAV2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and NAV2 expression is measured. Determine whether NAV2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of AP000688.8. Does this perturbation cause a significant change in AP000688.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of AP000688.8. Does this perturbation cause a significant change in AP000688.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Determine whether LRRC4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Determine whether LRRC4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3723,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ARHGAP11A expression is observed. Does this perturbation lead to a significant difference in ARHGAP11A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ARHGAP11A expression is observed. Does this perturbation lead to a significant difference in ARHGAP11A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
62,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RIOK3 expression is quantified. Does this perturbation result in a significant change in RIOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RIOK3 expression is quantified. Does this perturbation result in a significant change in RIOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KCNQ1OT1. Does perturbing EIF2B3 lead to a significant change in KCNQ1OT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KCNQ1OT1. Does perturbing EIF2B3 lead to a significant change in KCNQ1OT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4703,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of OBSCN. Does this perturbation cause a significant change in OBSCN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of OBSCN. Does this perturbation cause a significant change in OBSCN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3960,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and RP11-573D15.9 expression is measured. Determine whether RP11-573D15.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and RP11-573D15.9 expression is measured. Determine whether RP11-573D15.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4433,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of DOCK11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of DOCK11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4740,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Does this perturbation cause a significant change in PAXBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Does this perturbation cause a significant change in PAXBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AMOTL1 expression is quantified. Does this perturbation result in a significant change in AMOTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AMOTL1 expression is quantified. Does this perturbation result in a significant change in AMOTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in TFPI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in TFPI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3220,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Does this perturbation cause a significant change in ZNF789 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Does this perturbation cause a significant change in ZNF789 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
778,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor JUND expression. Decide whether this perturbation leads to a significant alteration in JUND expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor JUND expression. Decide whether this perturbation leads to a significant alteration in JUND expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of C1GALT1. Does perturbing GNPNAT1 lead to a significant change in C1GALT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of C1GALT1. Does perturbing GNPNAT1 lead to a significant change in C1GALT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Determine whether HIST1H1E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Determine whether HIST1H1E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of TMOD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of TMOD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of SPINK5. Does this perturbation cause a significant change in SPINK5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of SPINK5. Does this perturbation cause a significant change in SPINK5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of HP1BP3. Does this perturbation cause a significant change in HP1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of HP1BP3. Does this perturbation cause a significant change in HP1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KCNQ1OT1. Does this perturbation cause a significant change in KCNQ1OT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KCNQ1OT1. Does this perturbation cause a significant change in KCNQ1OT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2843,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Determine whether PDK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Determine whether PDK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
840,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Determine whether SRP72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Determine whether SRP72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Determine whether RP11-789C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Determine whether RP11-789C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of HERPUD1. Does perturbing FECH lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of HERPUD1. Does perturbing FECH lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Determine whether GATA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Determine whether GATA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IDH3A expression is quantified. Does this perturbation result in a significant change in IDH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IDH3A expression is quantified. Does this perturbation result in a significant change in IDH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of PPP1R16B. Does perturbing PPWD1 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of PPP1R16B. Does perturbing PPWD1 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ATP6V1B2. Does perturbing PDIA6 lead to a significant change in ATP6V1B2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ATP6V1B2. Does perturbing PDIA6 lead to a significant change in ATP6V1B2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3343,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SIGLEC6 expression is observed. Does this perturbation lead to a significant difference in SIGLEC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SIGLEC6 expression is observed. Does this perturbation lead to a significant difference in SIGLEC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4628,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KCNQ1OT1 expression. Decide whether this perturbation leads to a significant alteration in KCNQ1OT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KCNQ1OT1 expression. Decide whether this perturbation leads to a significant alteration in KCNQ1OT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2718,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is measured. Determine whether RP11-435O5.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is measured. Determine whether RP11-435O5.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and FOXO6 expression is quantified. Does this perturbation result in a significant change in FOXO6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and FOXO6 expression is quantified. Does this perturbation result in a significant change in FOXO6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4170,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Does this perturbation cause a significant change in FGF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Does this perturbation cause a significant change in FGF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is measured. Determine whether RP11-15E18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is measured. Determine whether RP11-15E18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3578,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor APOBEC3D expression. Decide whether this perturbation leads to a significant alteration in APOBEC3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor APOBEC3D expression. Decide whether this perturbation leads to a significant alteration in APOBEC3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
843,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3763,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and RNF19A expression is observed. Does this perturbation lead to a significant difference in RNF19A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and RNF19A expression is observed. Does this perturbation lead to a significant difference in RNF19A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MLEC. Does this perturbation cause a significant change in MLEC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MLEC. Does this perturbation cause a significant change in MLEC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Determine whether CDKN2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Determine whether CDKN2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2053,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of GMEB1. Does perturbing DDRGK1 lead to a significant change in GMEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of GMEB1. Does perturbing DDRGK1 lead to a significant change in GMEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4103,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and LINC00938 expression is observed. Does this perturbation lead to a significant difference in LINC00938 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and LINC00938 expression is observed. Does this perturbation lead to a significant difference in LINC00938 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of AC018878.3. Does this perturbation cause a significant change in AC018878.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of AC018878.3. Does this perturbation cause a significant change in AC018878.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of STC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of STC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Determine whether DNTTIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Determine whether DNTTIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Determine whether RP11-146D12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Determine whether RP11-146D12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Determine whether PBDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Determine whether PBDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in TAGLN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in TAGLN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and MTPN expression is quantified. Does this perturbation result in a significant change in MTPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and MTPN expression is quantified. Does this perturbation result in a significant change in MTPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2870,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Does this perturbation cause a significant change in RGS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Does this perturbation cause a significant change in RGS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2990,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
370,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Does this perturbation cause a significant change in HMGCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Does this perturbation cause a significant change in HMGCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and SRP72 expression is quantified. Does this perturbation result in a significant change in SRP72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and SRP72 expression is quantified. Does this perturbation result in a significant change in SRP72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Determine whether CTCFL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Determine whether CTCFL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
420,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Does this perturbation cause a significant change in CD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Does this perturbation cause a significant change in CD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of SSBP2. Does perturbing COPB1 lead to a significant change in SSBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of SSBP2. Does perturbing COPB1 lead to a significant change in SSBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2578,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ACE expression. Decide whether this perturbation leads to a significant alteration in ACE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ACE expression. Decide whether this perturbation leads to a significant alteration in ACE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4208,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of GOT1. Does perturbing SOCS1 lead to a significant change in GOT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of GOT1. Does perturbing SOCS1 lead to a significant change in GOT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is measured. Determine whether RP11-81A22.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is measured. Determine whether RP11-81A22.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of FYTTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of FYTTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5118,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor GATA2 expression. Decide whether this perturbation leads to a significant alteration in GATA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor GATA2 expression. Decide whether this perturbation leads to a significant alteration in GATA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of KLF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of KLF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4418,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor AC005540.3 expression. Decide whether this perturbation leads to a significant alteration in AC005540.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor AC005540.3 expression. Decide whether this perturbation leads to a significant alteration in AC005540.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1013,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and KCNE3 expression is observed. Does this perturbation lead to a significant difference in KCNE3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and KCNE3 expression is observed. Does this perturbation lead to a significant difference in KCNE3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of PCK2. Does perturbing SEC61A1 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of PCK2. Does perturbing SEC61A1 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP11-2H8.2. Does perturbing SRP68 lead to a significant change in RP11-2H8.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP11-2H8.2. Does perturbing SRP68 lead to a significant change in RP11-2H8.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5070,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Does this perturbation cause a significant change in ERP29 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Does this perturbation cause a significant change in ERP29 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and SHOX2 expression is measured. Determine whether SHOX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and SHOX2 expression is measured. Determine whether SHOX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ATAD2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ATAD2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in AC015987.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in AC015987.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ZNF292. Does perturbing SRP68 lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ZNF292. Does perturbing SRP68 lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of GUSB. Does perturbing SAMM50 lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of GUSB. Does perturbing SAMM50 lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
86,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Determine whether PHF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Determine whether PHF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KIAA1586. Does perturbing EIF2B3 lead to a significant change in KIAA1586 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KIAA1586. Does perturbing EIF2B3 lead to a significant change in KIAA1586 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3503,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RDH10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RDH10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and MORF4L2 expression is quantified. Does this perturbation result in a significant change in MORF4L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and MORF4L2 expression is quantified. Does this perturbation result in a significant change in MORF4L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and JUND expression is measured. Determine whether JUND exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and JUND expression is measured. Determine whether JUND exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and NOSTRIN expression is quantified. Does this perturbation result in a significant change in NOSTRIN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and NOSTRIN expression is quantified. Does this perturbation result in a significant change in NOSTRIN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-838N2.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-838N2.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of HPCAL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of HPCAL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ATP11B expression is quantified. Does this perturbation result in a significant change in ATP11B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ATP11B expression is quantified. Does this perturbation result in a significant change in ATP11B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1978,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor CRNDE expression. Decide whether this perturbation leads to a significant alteration in CRNDE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor CRNDE expression. Decide whether this perturbation leads to a significant alteration in CRNDE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Determine whether AC015987.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Determine whether AC015987.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
850,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Does this perturbation cause a significant change in ATF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Does this perturbation cause a significant change in ATF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Determine whether CTD-2587M2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Determine whether CTD-2587M2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1688,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ESCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ESCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and RAD51AP1 expression is measured. Determine whether RAD51AP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and RAD51AP1 expression is measured. Determine whether RAD51AP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CTCFL. Does perturbing SEC63 lead to a significant change in CTCFL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CTCFL. Does perturbing SEC63 lead to a significant change in CTCFL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HIST1H1E expression is quantified. Does this perturbation result in a significant change in HIST1H1E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HIST1H1E expression is quantified. Does this perturbation result in a significant change in HIST1H1E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and DDIT4 expression is measured. Determine whether DDIT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and DDIT4 expression is measured. Determine whether DDIT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TET1 expression is measured. Determine whether TET1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TET1 expression is measured. Determine whether TET1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Determine whether CHD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Determine whether CHD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is measured. Determine whether RP11-65L19.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is measured. Determine whether RP11-65L19.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and RCBTB2 expression is quantified. Does this perturbation result in a significant change in RCBTB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and RCBTB2 expression is quantified. Does this perturbation result in a significant change in RCBTB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RIMS3. Does this perturbation cause a significant change in RIMS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RIMS3. Does this perturbation cause a significant change in RIMS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of RP11-247A12.2. Does this perturbation cause a significant change in RP11-247A12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of RP11-247A12.2. Does this perturbation cause a significant change in RP11-247A12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ATAD2B expression is measured. Determine whether ATAD2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ATAD2B expression is measured. Determine whether ATAD2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and OXLD1 expression is measured. Determine whether OXLD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and OXLD1 expression is measured. Determine whether OXLD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in GSN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in GSN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TRIM38. Does perturbing SRP72 lead to a significant change in TRIM38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TRIM38. Does perturbing SRP72 lead to a significant change in TRIM38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of RNF19A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of RNF19A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of TFPI. Does this perturbation cause a significant change in TFPI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of TFPI. Does this perturbation cause a significant change in TFPI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP11-15E18.1. Does this perturbation cause a significant change in RP11-15E18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP11-15E18.1. Does this perturbation cause a significant change in RP11-15E18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CLDN11. Does perturbing SEC63 lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CLDN11. Does perturbing SEC63 lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ZC3H7A. Does this perturbation cause a significant change in ZC3H7A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ZC3H7A. Does this perturbation cause a significant change in ZC3H7A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in PHF21A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in PHF21A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in PDRG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in PDRG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of MORC2-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of MORC2-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of EIF4B. Does this perturbation cause a significant change in EIF4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of EIF4B. Does this perturbation cause a significant change in EIF4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1098,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-328J2.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-328J2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-328J2.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-328J2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1138,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in SRP72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in SRP72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MT2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MT2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of REST. Does this perturbation cause a significant change in REST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of REST. Does this perturbation cause a significant change in REST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and STC2 expression is quantified. Does this perturbation result in a significant change in STC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and STC2 expression is quantified. Does this perturbation result in a significant change in STC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ATP6AP2 expression is quantified. Does this perturbation result in a significant change in ATP6AP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ATP6AP2 expression is quantified. Does this perturbation result in a significant change in ATP6AP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1168,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor KDM1B expression. Decide whether this perturbation leads to a significant alteration in KDM1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor KDM1B expression. Decide whether this perturbation leads to a significant alteration in KDM1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in UFD1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in UFD1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1153,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SLC37A1 expression is observed. Does this perturbation lead to a significant difference in SLC37A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SLC37A1 expression is observed. Does this perturbation lead to a significant difference in SLC37A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4260,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Does this perturbation cause a significant change in RASGRP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Does this perturbation cause a significant change in RASGRP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4778,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor HIST1H2BC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2BC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor HIST1H2BC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2BC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4410,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Does this perturbation cause a significant change in AC005540.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Does this perturbation cause a significant change in AC005540.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1738,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor USP37 expression. Decide whether this perturbation leads to a significant alteration in USP37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor USP37 expression. Decide whether this perturbation leads to a significant alteration in USP37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in UHRF1BP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in UHRF1BP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2888,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-499F3.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-499F3.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-499F3.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-499F3.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TSPAN33 expression is quantified. Does this perturbation result in a significant change in TSPAN33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TSPAN33 expression is quantified. Does this perturbation result in a significant change in TSPAN33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2008,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor C1GALT1 expression. Decide whether this perturbation leads to a significant alteration in C1GALT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor C1GALT1 expression. Decide whether this perturbation leads to a significant alteration in C1GALT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and HLA-AS1 expression is quantified. Does this perturbation result in a significant change in HLA-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and HLA-AS1 expression is quantified. Does this perturbation result in a significant change in HLA-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Determine whether CYP17A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Determine whether CYP17A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
95,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-141B14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-141B14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of NTRK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of NTRK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and COPB1 expression is measured. Determine whether COPB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and COPB1 expression is measured. Determine whether COPB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2800,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of RP11-322J23.1. Does this perturbation cause a significant change in RP11-322J23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of RP11-322J23.1. Does this perturbation cause a significant change in RP11-322J23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Determine whether CTBS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Determine whether CTBS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of FAM114A1. Does this perturbation cause a significant change in FAM114A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of FAM114A1. Does this perturbation cause a significant change in FAM114A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ANKLE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ANKLE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PSMD14 expression is quantified. Does this perturbation result in a significant change in PSMD14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PSMD14 expression is quantified. Does this perturbation result in a significant change in PSMD14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of POU2F2. Does perturbing HARS lead to a significant change in POU2F2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of POU2F2. Does perturbing HARS lead to a significant change in POU2F2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in KCTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in KCTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of BIRC5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of BIRC5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1588,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3000,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of H1FX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of H1FX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1008,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor RP11-334C17.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-334C17.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor RP11-334C17.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-334C17.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
440,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of CDRT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of CDRT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2120,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TTC32 expression is measured. Determine whether TTC32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TTC32 expression is measured. Determine whether TTC32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of DDIT4. Does this perturbation cause a significant change in DDIT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of DDIT4. Does this perturbation cause a significant change in DDIT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDKN2C expression is measured. Determine whether CDKN2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDKN2C expression is measured. Determine whether CDKN2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is quantified. Does this perturbation result in a significant change in RP11-390B4.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is quantified. Does this perturbation result in a significant change in RP11-390B4.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Determine whether SIGLEC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Determine whether SIGLEC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2790,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PIK3IP1. Does perturbing SEC61B lead to a significant change in PIK3IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PIK3IP1. Does perturbing SEC61B lead to a significant change in PIK3IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and HIST1H1D expression is quantified. Does this perturbation result in a significant change in HIST1H1D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and HIST1H1D expression is quantified. Does this perturbation result in a significant change in HIST1H1D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and UFD1L expression is measured. Determine whether UFD1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and UFD1L expression is measured. Determine whether UFD1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in RGS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in RGS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of DKFZP779L1853 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of DKFZP779L1853 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4163,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and SSBP2 expression is observed. Does this perturbation lead to a significant difference in SSBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and SSBP2 expression is observed. Does this perturbation lead to a significant difference in SSBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5108,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor PIK3R1 expression. Decide whether this perturbation leads to a significant alteration in PIK3R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor PIK3R1 expression. Decide whether this perturbation leads to a significant alteration in PIK3R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in PITPNB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in PITPNB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and UHMK1 expression is measured. Determine whether UHMK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and UHMK1 expression is measured. Determine whether UHMK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
868,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ESCO1 expression. Decide whether this perturbation leads to a significant alteration in ESCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ESCO1 expression. Decide whether this perturbation leads to a significant alteration in ESCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SLBP expression is measured. Determine whether SLBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SLBP expression is measured. Determine whether SLBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RP11-16E12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RP11-16E12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
718,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor FAM114A1 expression. Decide whether this perturbation leads to a significant alteration in FAM114A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor FAM114A1 expression. Decide whether this perturbation leads to a significant alteration in FAM114A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is measured. Determine whether RP11-24F11.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is measured. Determine whether RP11-24F11.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ZFP36L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ZFP36L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4960,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Does this perturbation cause a significant change in EIF4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Does this perturbation cause a significant change in EIF4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1460,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of TLK2. Does perturbing GNPNAT1 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of TLK2. Does perturbing GNPNAT1 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in IRF7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in IRF7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of RP11-61E11.1. Does perturbing SAMM50 lead to a significant change in RP11-61E11.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of RP11-61E11.1. Does perturbing SAMM50 lead to a significant change in RP11-61E11.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
658,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor POU2F2 expression. Decide whether this perturbation leads to a significant alteration in POU2F2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor POU2F2 expression. Decide whether this perturbation leads to a significant alteration in POU2F2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in RP11-38P22.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in RP11-38P22.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of C19orf59 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of C19orf59 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2403,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and HP1BP3 expression is measured. Determine whether HP1BP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and HP1BP3 expression is measured. Determine whether HP1BP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ACE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ACE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5068,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CTSV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CTSV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in RP11-573D15.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in RP11-573D15.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1860,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Does this perturbation cause a significant change in TACC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Does this perturbation cause a significant change in TACC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of SPAST. Does perturbing DARS lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of SPAST. Does perturbing DARS lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of IDS. Does perturbing AARS lead to a significant change in IDS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of IDS. Does perturbing AARS lead to a significant change in IDS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
870,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Does this perturbation cause a significant change in RSL24D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Does this perturbation cause a significant change in RSL24D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
693,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and SPCS2 expression is observed. Does this perturbation lead to a significant difference in SPCS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and SPCS2 expression is observed. Does this perturbation lead to a significant difference in SPCS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and IL32 expression is quantified. Does this perturbation result in a significant change in IL32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and IL32 expression is quantified. Does this perturbation result in a significant change in IL32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Determine whether RAI14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Determine whether RAI14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4373,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and RP11-181G12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-181G12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and RP11-181G12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-181G12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Determine whether KLF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Determine whether KLF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ATP6AP2 expression is measured. Determine whether ATP6AP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ATP6AP2 expression is measured. Determine whether ATP6AP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of RP11-138C9.1. Does perturbing TIMM23 lead to a significant change in RP11-138C9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of RP11-138C9.1. Does perturbing TIMM23 lead to a significant change in RP11-138C9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is measured. Determine whether RP11-390B4.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is measured. Determine whether RP11-390B4.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2230,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Does this perturbation cause a significant change in FAM212A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Does this perturbation cause a significant change in FAM212A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of GATA3. Does perturbing AMIGO3 lead to a significant change in GATA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of GATA3. Does perturbing AMIGO3 lead to a significant change in GATA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of POLR2J3. Does perturbing HYOU1 lead to a significant change in POLR2J3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of POLR2J3. Does perturbing HYOU1 lead to a significant change in POLR2J3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and PDK2 expression is quantified. Does this perturbation result in a significant change in PDK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and PDK2 expression is quantified. Does this perturbation result in a significant change in PDK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3118,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor NXF1 expression. Decide whether this perturbation leads to a significant alteration in NXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor NXF1 expression. Decide whether this perturbation leads to a significant alteration in NXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in JARID2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in JARID2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
28,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of TMEM60. Does perturbing TMED2 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of TMEM60. Does perturbing TMED2 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3368,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ANKLE2 expression is quantified. Does this perturbation result in a significant change in ANKLE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ANKLE2 expression is quantified. Does this perturbation result in a significant change in ANKLE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and PTBP3 expression is quantified. Does this perturbation result in a significant change in PTBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and PTBP3 expression is quantified. Does this perturbation result in a significant change in PTBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and RP11-430H10.1 expression is measured. Determine whether RP11-430H10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and RP11-430H10.1 expression is measured. Determine whether RP11-430H10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of OPTN. Does this perturbation cause a significant change in OPTN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of OPTN. Does this perturbation cause a significant change in OPTN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is quantified. Does this perturbation result in a significant change in CTD-2001C12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is quantified. Does this perturbation result in a significant change in CTD-2001C12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of C6orf120 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of C6orf120 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4423,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RP11-157D23.2 expression is observed. Does this perturbation lead to a significant difference in RP11-157D23.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RP11-157D23.2 expression is observed. Does this perturbation lead to a significant difference in RP11-157D23.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
92,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is quantified. Does this perturbation result in a significant change in RP11-141B14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is quantified. Does this perturbation result in a significant change in RP11-141B14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of TAGLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of TAGLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3943,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ROBO1 expression is observed. Does this perturbation lead to a significant difference in ROBO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ROBO1 expression is observed. Does this perturbation lead to a significant difference in ROBO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TRPM4 expression is quantified. Does this perturbation result in a significant change in TRPM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TRPM4 expression is quantified. Does this perturbation result in a significant change in TRPM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and OPTN expression is quantified. Does this perturbation result in a significant change in OPTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and OPTN expression is quantified. Does this perturbation result in a significant change in OPTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
770,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Does this perturbation cause a significant change in JUND expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Does this perturbation cause a significant change in JUND expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of RP11-38P22.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of RP11-38P22.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in SKIL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in SKIL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and JUND expression is quantified. Does this perturbation result in a significant change in JUND expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and JUND expression is quantified. Does this perturbation result in a significant change in JUND expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of LST1. Does perturbing DNAJC19 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of LST1. Does perturbing DNAJC19 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is measured. Determine whether RP11-181G12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is measured. Determine whether RP11-181G12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of SLC27A2. Does perturbing TIMM44 lead to a significant change in SLC27A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of SLC27A2. Does perturbing TIMM44 lead to a significant change in SLC27A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is measured. Determine whether RP11-838N2.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is measured. Determine whether RP11-838N2.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3948,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ROBO1 expression. Decide whether this perturbation leads to a significant alteration in ROBO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ROBO1 expression. Decide whether this perturbation leads to a significant alteration in ROBO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
38,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor CASP4 expression. Decide whether this perturbation leads to a significant alteration in CASP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor CASP4 expression. Decide whether this perturbation leads to a significant alteration in CASP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and SKIL expression is quantified. Does this perturbation result in a significant change in SKIL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and SKIL expression is quantified. Does this perturbation result in a significant change in SKIL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and GRN expression is measured. Determine whether GRN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and GRN expression is measured. Determine whether GRN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of AP000688.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of AP000688.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2588,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor KIF4A expression. Decide whether this perturbation leads to a significant alteration in KIF4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor KIF4A expression. Decide whether this perturbation leads to a significant alteration in KIF4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in IDS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in IDS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AFF1. Does perturbing TARS lead to a significant change in AFF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AFF1. Does perturbing TARS lead to a significant change in AFF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1370,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Does this perturbation cause a significant change in KCTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Does this perturbation cause a significant change in KCTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1618,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor RP11-81A22.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-81A22.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor RP11-81A22.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-81A22.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in RP11-95O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in RP11-95O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
180,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Does this perturbation cause a significant change in STC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Does this perturbation cause a significant change in STC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-65L19.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-65L19.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3050,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Does this perturbation cause a significant change in RP11-363D14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Does this perturbation cause a significant change in RP11-363D14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IDH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IDH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1920,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Does this perturbation cause a significant change in AKAP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Does this perturbation cause a significant change in AKAP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of IL8. Does this perturbation cause a significant change in IL8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of IL8. Does this perturbation cause a significant change in IL8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and WDR72 expression is quantified. Does this perturbation result in a significant change in WDR72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and WDR72 expression is quantified. Does this perturbation result in a significant change in WDR72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
258,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor LINC00657 expression. Decide whether this perturbation leads to a significant alteration in LINC00657 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor LINC00657 expression. Decide whether this perturbation leads to a significant alteration in LINC00657 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2880,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Does this perturbation cause a significant change in RP11-499F3.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Does this perturbation cause a significant change in RP11-499F3.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AC007038.7. Does this perturbation cause a significant change in AC007038.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AC007038.7. Does this perturbation cause a significant change in AC007038.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
91,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-141B14.1. Does perturbing ZNF326 lead to a significant change in RP11-141B14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-141B14.1. Does perturbing ZNF326 lead to a significant change in RP11-141B14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of CRNDE. Does this perturbation cause a significant change in CRNDE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of CRNDE. Does this perturbation cause a significant change in CRNDE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Determine whether KCNQ1OT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Determine whether KCNQ1OT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP1-274L7.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP1-274L7.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in PRRC2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in PRRC2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and HM13 expression is quantified. Does this perturbation result in a significant change in HM13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and HM13 expression is quantified. Does this perturbation result in a significant change in HM13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4118,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor CDCA3 expression. Decide whether this perturbation leads to a significant alteration in CDCA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor CDCA3 expression. Decide whether this perturbation leads to a significant alteration in CDCA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
878,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor RSL24D1 expression. Decide whether this perturbation leads to a significant alteration in RSL24D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor RSL24D1 expression. Decide whether this perturbation leads to a significant alteration in RSL24D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Determine whether PDE3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Determine whether PDE3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2480,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Does this perturbation cause a significant change in HLTF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Does this perturbation cause a significant change in HLTF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Determine whether HIST1H3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Determine whether HIST1H3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Determine whether SNRNP25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Determine whether SNRNP25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and KHDC1L expression is measured. Determine whether KHDC1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and KHDC1L expression is measured. Determine whether KHDC1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1980,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Does this perturbation cause a significant change in KLF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Does this perturbation cause a significant change in KLF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and RP11-666A20.4 expression is measured. Determine whether RP11-666A20.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and RP11-666A20.4 expression is measured. Determine whether RP11-666A20.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of TMEM87B. Does this perturbation cause a significant change in TMEM87B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of TMEM87B. Does this perturbation cause a significant change in TMEM87B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Determine whether FYTTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Determine whether FYTTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of UBE3A. Does this perturbation cause a significant change in UBE3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of UBE3A. Does this perturbation cause a significant change in UBE3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1560,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Does this perturbation cause a significant change in DOCK8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Does this perturbation cause a significant change in DOCK8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1358,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor TAGLN expression. Decide whether this perturbation leads to a significant alteration in TAGLN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor TAGLN expression. Decide whether this perturbation leads to a significant alteration in TAGLN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TRIM38 expression is measured. Determine whether TRIM38 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TRIM38 expression is measured. Determine whether TRIM38 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ANKLE2. Does perturbing TELO2 lead to a significant change in ANKLE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ANKLE2. Does perturbing TELO2 lead to a significant change in ANKLE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of TRAPPC10. Does perturbing GMPPB lead to a significant change in TRAPPC10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of TRAPPC10. Does perturbing GMPPB lead to a significant change in TRAPPC10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of TLN1. Does perturbing IARS2 lead to a significant change in TLN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of TLN1. Does perturbing IARS2 lead to a significant change in TLN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EGLN3. Does this perturbation cause a significant change in EGLN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EGLN3. Does this perturbation cause a significant change in EGLN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of FGF11. Does perturbing COPB1 lead to a significant change in FGF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of FGF11. Does perturbing COPB1 lead to a significant change in FGF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
873,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and RSL24D1 expression is observed. Does this perturbation lead to a significant difference in RSL24D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and RSL24D1 expression is observed. Does this perturbation lead to a significant difference in RSL24D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1053,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and RP11-38P22.2 expression is observed. Does this perturbation lead to a significant difference in RP11-38P22.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and RP11-38P22.2 expression is observed. Does this perturbation lead to a significant difference in RP11-38P22.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is quantified. Does this perturbation result in a significant change in RP11-15E18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is quantified. Does this perturbation result in a significant change in RP11-15E18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of RP11-81A22.5. Does perturbing PDIA6 lead to a significant change in RP11-81A22.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of RP11-81A22.5. Does perturbing PDIA6 lead to a significant change in RP11-81A22.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2490,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Does this perturbation cause a significant change in CD58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Does this perturbation cause a significant change in CD58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ATP2A3. Does this perturbation cause a significant change in ATP2A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ATP2A3. Does this perturbation cause a significant change in ATP2A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Determine whether HIST1H2AC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Determine whether HIST1H2AC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2023,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ABI2 expression is observed. Does this perturbation lead to a significant difference in ABI2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ABI2 expression is observed. Does this perturbation lead to a significant difference in ABI2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and SSBP2 expression is measured. Determine whether SSBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and SSBP2 expression is measured. Determine whether SSBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Determine whether CTD-2267D19.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Determine whether CTD-2267D19.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Determine whether AC018878.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Determine whether AC018878.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3590,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Does this perturbation cause a significant change in RP11-2H8.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Does this perturbation cause a significant change in RP11-2H8.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2733,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and PDRG1 expression is measured. Determine whether PDRG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and PDRG1 expression is measured. Determine whether PDRG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3018,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP11-15E18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP11-15E18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
36,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Determine whether CASP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Determine whether CASP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4858,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor STK17B expression. Decide whether this perturbation leads to a significant alteration in STK17B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor STK17B expression. Decide whether this perturbation leads to a significant alteration in STK17B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3618,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor TIPARP expression. Decide whether this perturbation leads to a significant alteration in TIPARP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor TIPARP expression. Decide whether this perturbation leads to a significant alteration in TIPARP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ERP29 expression is quantified. Does this perturbation result in a significant change in ERP29 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ERP29 expression is quantified. Does this perturbation result in a significant change in ERP29 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
358,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CTSV expression is quantified. Does this perturbation result in a significant change in CTSV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CTSV expression is quantified. Does this perturbation result in a significant change in CTSV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and DUSP21 expression is quantified. Does this perturbation result in a significant change in DUSP21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and DUSP21 expression is quantified. Does this perturbation result in a significant change in DUSP21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1430,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Does this perturbation cause a significant change in MARCH8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Does this perturbation cause a significant change in MARCH8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and IL13RA1 expression is quantified. Does this perturbation result in a significant change in IL13RA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and IL13RA1 expression is quantified. Does this perturbation result in a significant change in IL13RA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in PIK3R3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in PIK3R3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of LINC01031. Does this perturbation cause a significant change in LINC01031 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of LINC01031. Does this perturbation cause a significant change in LINC01031 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is quantified. Does this perturbation result in a significant change in CTC-550B14.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is quantified. Does this perturbation result in a significant change in CTC-550B14.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in RNF139-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in RNF139-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of CTNNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of CTNNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of RP11-573D15.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of RP11-573D15.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in DDIT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in DDIT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is measured. Determine whether RP11-242O24.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is measured. Determine whether RP11-242O24.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3708,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor PARP11 expression. Decide whether this perturbation leads to a significant alteration in PARP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor PARP11 expression. Decide whether this perturbation leads to a significant alteration in PARP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2523,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and RNF139-AS1 expression is observed. Does this perturbation lead to a significant difference in RNF139-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and RNF139-AS1 expression is observed. Does this perturbation lead to a significant difference in RNF139-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and C19orf59 expression is quantified. Does this perturbation result in a significant change in C19orf59 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and C19orf59 expression is quantified. Does this perturbation result in a significant change in C19orf59 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Determine whether MT2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Determine whether MT2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of RP11-38P22.2. Does this perturbation cause a significant change in RP11-38P22.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of RP11-38P22.2. Does this perturbation cause a significant change in RP11-38P22.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of NFE2L3. Does perturbing PDIA6 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of NFE2L3. Does perturbing PDIA6 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of HP1BP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of HP1BP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4878,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor S100A10 expression. Decide whether this perturbation leads to a significant alteration in S100A10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor S100A10 expression. Decide whether this perturbation leads to a significant alteration in S100A10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3953,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and SERPINF2 expression is observed. Does this perturbation lead to a significant difference in SERPINF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and SERPINF2 expression is observed. Does this perturbation lead to a significant difference in SERPINF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1960,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1300,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Does this perturbation cause a significant change in ITGB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Does this perturbation cause a significant change in ITGB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3713,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and C17orf64 expression is observed. Does this perturbation lead to a significant difference in C17orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and C17orf64 expression is observed. Does this perturbation lead to a significant difference in C17orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ZCCHC11. Does perturbing P4HB lead to a significant change in ZCCHC11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ZCCHC11. Does perturbing P4HB lead to a significant change in ZCCHC11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Determine whether RP11-573D15.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Determine whether RP11-573D15.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and MED13 expression is measured. Determine whether MED13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and MED13 expression is measured. Determine whether MED13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EGLN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EGLN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and S100A10 expression is measured. Determine whether S100A10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and S100A10 expression is measured. Determine whether S100A10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Determine whether GRN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Determine whether GRN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
130,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Does this perturbation cause a significant change in TET1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Does this perturbation cause a significant change in TET1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Determine whether GCKR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Determine whether GCKR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1383,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ZEB1 expression is observed. Does this perturbation lead to a significant difference in ZEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ZEB1 expression is observed. Does this perturbation lead to a significant difference in ZEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of CTD-2020K17.1. Does perturbing COPB1 lead to a significant change in CTD-2020K17.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of CTD-2020K17.1. Does perturbing COPB1 lead to a significant change in CTD-2020K17.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CD9. Does this perturbation cause a significant change in CD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CD9. Does this perturbation cause a significant change in CD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and C12orf23 expression is measured. Determine whether C12orf23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and C12orf23 expression is measured. Determine whether C12orf23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of PLA2G15. Does this perturbation cause a significant change in PLA2G15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of PLA2G15. Does this perturbation cause a significant change in PLA2G15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CDT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CDT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1990,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EPS15 expression is quantified. Does this perturbation result in a significant change in EPS15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EPS15 expression is quantified. Does this perturbation result in a significant change in EPS15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3060,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Does this perturbation cause a significant change in PHF19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Does this perturbation cause a significant change in PHF19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of TGOLN2. Does this perturbation cause a significant change in TGOLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of TGOLN2. Does this perturbation cause a significant change in TGOLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4223,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IFT27 expression is observed. Does this perturbation lead to a significant difference in IFT27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IFT27 expression is observed. Does this perturbation lead to a significant difference in IFT27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and SLFNL1 expression is quantified. Does this perturbation result in a significant change in SLFNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and SLFNL1 expression is quantified. Does this perturbation result in a significant change in SLFNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3923,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and PPM1N expression is observed. Does this perturbation lead to a significant difference in PPM1N expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and PPM1N expression is observed. Does this perturbation lead to a significant difference in PPM1N expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is quantified. Does this perturbation result in a significant change in CYP17A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is quantified. Does this perturbation result in a significant change in CYP17A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2318,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ANKLE2 expression. Decide whether this perturbation leads to a significant alteration in ANKLE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ANKLE2 expression. Decide whether this perturbation leads to a significant alteration in ANKLE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in GNPTG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in GNPTG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2298,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor KLF6 expression. Decide whether this perturbation leads to a significant alteration in KLF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor KLF6 expression. Decide whether this perturbation leads to a significant alteration in KLF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RNF8 expression is quantified. Does this perturbation result in a significant change in RNF8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RNF8 expression is quantified. Does this perturbation result in a significant change in RNF8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3983,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and UBE2V1 expression is measured. Determine whether UBE2V1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and UBE2V1 expression is measured. Determine whether UBE2V1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA0922 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA0922 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CD9. Does perturbing SRPR lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CD9. Does perturbing SRPR lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in ATP6AP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in ATP6AP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4653,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KIAA1586 expression is observed. Does this perturbation lead to a significant difference in KIAA1586 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KIAA1586 expression is observed. Does this perturbation lead to a significant difference in KIAA1586 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
32,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and CASP4 expression is quantified. Does this perturbation result in a significant change in CASP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and CASP4 expression is quantified. Does this perturbation result in a significant change in CASP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in CDRT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in CDRT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2180,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2463,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and NUFIP2 expression is observed. Does this perturbation lead to a significant difference in NUFIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and NUFIP2 expression is observed. Does this perturbation lead to a significant difference in NUFIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CHST12. Does this perturbation cause a significant change in CHST12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CHST12. Does this perturbation cause a significant change in CHST12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Determine whether NPDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Determine whether NPDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4068,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor CENPF expression. Decide whether this perturbation leads to a significant alteration in CENPF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor CENPF expression. Decide whether this perturbation leads to a significant alteration in CENPF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1448,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor AC079466.1 expression. Decide whether this perturbation leads to a significant alteration in AC079466.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor AC079466.1 expression. Decide whether this perturbation leads to a significant alteration in AC079466.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
663,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and PTBP3 expression is observed. Does this perturbation lead to a significant difference in PTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and PTBP3 expression is observed. Does this perturbation lead to a significant difference in PTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2640,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Does this perturbation cause a significant change in IDH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Does this perturbation cause a significant change in IDH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1040,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Does this perturbation cause a significant change in HRK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Does this perturbation cause a significant change in HRK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2638,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor HAGH expression. Decide whether this perturbation leads to a significant alteration in HAGH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor HAGH expression. Decide whether this perturbation leads to a significant alteration in HAGH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
538,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor IRF7 expression. Decide whether this perturbation leads to a significant alteration in IRF7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor IRF7 expression. Decide whether this perturbation leads to a significant alteration in IRF7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
31,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of CASP4. Does perturbing CREB1 lead to a significant change in CASP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of CASP4. Does perturbing CREB1 lead to a significant change in CASP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
510,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Does this perturbation cause a significant change in PDE4D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Does this perturbation cause a significant change in PDE4D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ZXDA expression is measured. Determine whether ZXDA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ZXDA expression is measured. Determine whether ZXDA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TRPM4. Does perturbing DDOST lead to a significant change in TRPM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TRPM4. Does perturbing DDOST lead to a significant change in TRPM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Determine whether S100A10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Determine whether S100A10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1903,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC008074.3 expression is observed. Does this perturbation lead to a significant difference in AC008074.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC008074.3 expression is observed. Does this perturbation lead to a significant difference in AC008074.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
118,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-65L19.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-65L19.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-65L19.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-65L19.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Determine whether GALNT7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Determine whether GALNT7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Determine whether KIAA1432 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Determine whether KIAA1432 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ERV3-1. Does this perturbation cause a significant change in ERV3-1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ERV3-1. Does this perturbation cause a significant change in ERV3-1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1230,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Does this perturbation cause a significant change in SRP72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Does this perturbation cause a significant change in SRP72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RDH10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RDH10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CHST12 expression is quantified. Does this perturbation result in a significant change in CHST12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CHST12 expression is quantified. Does this perturbation result in a significant change in CHST12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
700,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Does this perturbation cause a significant change in UQCRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Does this perturbation cause a significant change in UQCRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and DDX3X expression is measured. Determine whether DDX3X exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and DDX3X expression is measured. Determine whether DDX3X exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SLC37A1 expression is quantified. Does this perturbation result in a significant change in SLC37A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SLC37A1 expression is quantified. Does this perturbation result in a significant change in SLC37A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Determine whether DYNC1H1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Determine whether DYNC1H1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and SNHG7 expression is quantified. Does this perturbation result in a significant change in SNHG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and SNHG7 expression is quantified. Does this perturbation result in a significant change in SNHG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AMOTL1. Does perturbing NEDD8 lead to a significant change in AMOTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AMOTL1. Does perturbing NEDD8 lead to a significant change in AMOTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Determine whether ZC3H7A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Determine whether ZC3H7A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CDT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CDT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CPQ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CPQ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
993,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and SHOX2 expression is observed. Does this perturbation lead to a significant difference in SHOX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and SHOX2 expression is observed. Does this perturbation lead to a significant difference in SHOX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4328,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor NOSTRIN expression. Decide whether this perturbation leads to a significant alteration in NOSTRIN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor NOSTRIN expression. Decide whether this perturbation leads to a significant alteration in NOSTRIN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and DNMBP expression is measured. Determine whether DNMBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and DNMBP expression is measured. Determine whether DNMBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and IL32 expression is measured. Determine whether IL32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and IL32 expression is measured. Determine whether IL32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of H3F3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of H3F3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is quantified. Does this perturbation result in a significant change in RP11-838N2.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is quantified. Does this perturbation result in a significant change in RP11-838N2.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3738,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor PITPNB expression. Decide whether this perturbation leads to a significant alteration in PITPNB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor PITPNB expression. Decide whether this perturbation leads to a significant alteration in PITPNB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1088,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor DDX3X expression. Decide whether this perturbation leads to a significant alteration in DDX3X expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor DDX3X expression. Decide whether this perturbation leads to a significant alteration in DDX3X expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
630,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Does this perturbation cause a significant change in VPS41 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Does this perturbation cause a significant change in VPS41 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2293,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and KLF6 expression is observed. Does this perturbation lead to a significant difference in KLF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and KLF6 expression is observed. Does this perturbation lead to a significant difference in KLF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EPB42. Does this perturbation cause a significant change in EPB42 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EPB42. Does this perturbation cause a significant change in EPB42 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of PHF21A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of PHF21A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of VAMP2. Does perturbing TARS lead to a significant change in VAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of VAMP2. Does perturbing TARS lead to a significant change in VAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
698,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor SPCS2 expression. Decide whether this perturbation leads to a significant alteration in SPCS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor SPCS2 expression. Decide whether this perturbation leads to a significant alteration in SPCS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2648,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IDH3A expression. Decide whether this perturbation leads to a significant alteration in IDH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IDH3A expression. Decide whether this perturbation leads to a significant alteration in IDH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and GCKR expression is measured. Determine whether GCKR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and GCKR expression is measured. Determine whether GCKR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2993,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CTD-2521M24.9 expression is observed. Does this perturbation lead to a significant difference in CTD-2521M24.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CTD-2521M24.9 expression is observed. Does this perturbation lead to a significant difference in CTD-2521M24.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and H3F3B expression is quantified. Does this perturbation result in a significant change in H3F3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and H3F3B expression is quantified. Does this perturbation result in a significant change in H3F3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of SKIL. Does perturbing ASCC3 lead to a significant change in SKIL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of SKIL. Does perturbing ASCC3 lead to a significant change in SKIL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Determine whether UFD1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Determine whether UFD1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and VPS41 expression is quantified. Does this perturbation result in a significant change in VPS41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and VPS41 expression is quantified. Does this perturbation result in a significant change in VPS41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4300,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Does this perturbation cause a significant change in GCKR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Does this perturbation cause a significant change in GCKR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and PBDC1 expression is measured. Determine whether PBDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and PBDC1 expression is measured. Determine whether PBDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of OXLD1. Does perturbing SEC61B lead to a significant change in OXLD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of OXLD1. Does perturbing SEC61B lead to a significant change in OXLD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
920,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4073,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP1-274L7.1 expression is observed. Does this perturbation lead to a significant difference in RP1-274L7.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP1-274L7.1 expression is observed. Does this perturbation lead to a significant difference in RP1-274L7.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Determine whether NSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Determine whether NSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1160,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Does this perturbation cause a significant change in KDM1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Does this perturbation cause a significant change in KDM1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ZC3H7A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ZC3H7A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3483,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and PTGS1 expression is observed. Does this perturbation lead to a significant difference in PTGS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and PTGS1 expression is observed. Does this perturbation lead to a significant difference in PTGS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is measured. Determine whether RP11-119J18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is measured. Determine whether RP11-119J18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3793,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and POLR2J3 expression is observed. Does this perturbation lead to a significant difference in POLR2J3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and POLR2J3 expression is observed. Does this perturbation lead to a significant difference in POLR2J3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and FGF11 expression is quantified. Does this perturbation result in a significant change in FGF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and FGF11 expression is quantified. Does this perturbation result in a significant change in FGF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in CENPF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in CENPF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of KDM1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of KDM1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Determine whether RSL24D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Determine whether RSL24D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of GS1-166A23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of GS1-166A23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2568,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor SBF2 expression. Decide whether this perturbation leads to a significant alteration in SBF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor SBF2 expression. Decide whether this perturbation leads to a significant alteration in SBF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in FGF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in FGF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3530,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Does this perturbation cause a significant change in FCGRT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Does this perturbation cause a significant change in FCGRT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in RP11-381O7.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in RP11-381O7.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
333,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4268,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RASGRP2 expression. Decide whether this perturbation leads to a significant alteration in RASGRP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RASGRP2 expression. Decide whether this perturbation leads to a significant alteration in RASGRP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and OXLD1 expression is quantified. Does this perturbation result in a significant change in OXLD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and OXLD1 expression is quantified. Does this perturbation result in a significant change in OXLD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Determine whether POLR2J3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Determine whether POLR2J3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Determine whether RIMS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Determine whether RIMS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of RP11-181G12.2. Does this perturbation cause a significant change in RP11-181G12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of RP11-181G12.2. Does this perturbation cause a significant change in RP11-181G12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
400,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Does this perturbation cause a significant change in RP11-90P5.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Does this perturbation cause a significant change in RP11-90P5.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3990,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Does this perturbation cause a significant change in RP11-242O24.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Does this perturbation cause a significant change in RP11-242O24.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ZC3H7A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ZC3H7A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and DNTTIP2 expression is measured. Determine whether DNTTIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and DNTTIP2 expression is measured. Determine whether DNTTIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of MS4A6E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of MS4A6E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and TACC3 expression is measured. Determine whether TACC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and TACC3 expression is measured. Determine whether TACC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Determine whether ATF7IP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Determine whether ATF7IP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1058,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor RP11-38P22.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-38P22.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor RP11-38P22.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-38P22.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of RGS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of RGS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and AC104532.4 expression is measured. Determine whether AC104532.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and AC104532.4 expression is measured. Determine whether AC104532.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3198,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TRIM24 expression. Decide whether this perturbation leads to a significant alteration in TRIM24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TRIM24 expression. Decide whether this perturbation leads to a significant alteration in TRIM24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
45,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in LPAR5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in LPAR5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4120,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Does this perturbation cause a significant change in FOXO6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Does this perturbation cause a significant change in FOXO6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Determine whether ROBO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Determine whether ROBO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of RP11-423O2.5. Does perturbing SEC61A1 lead to a significant change in RP11-423O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of RP11-423O2.5. Does perturbing SEC61A1 lead to a significant change in RP11-423O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5098,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor TGOLN2 expression. Decide whether this perturbation leads to a significant alteration in TGOLN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor TGOLN2 expression. Decide whether this perturbation leads to a significant alteration in TGOLN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Determine whether SPINK5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Determine whether SPINK5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of RP11-381O7.3. Does this perturbation cause a significant change in RP11-381O7.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of RP11-381O7.3. Does this perturbation cause a significant change in RP11-381O7.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3848,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TRPM4 expression. Decide whether this perturbation leads to a significant alteration in TRPM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TRPM4 expression. Decide whether this perturbation leads to a significant alteration in TRPM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4643,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and MBNL1 expression is measured. Determine whether MBNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and MBNL1 expression is measured. Determine whether MBNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Determine whether ERV3-1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Determine whether ERV3-1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and NBEAL2 expression is quantified. Does this perturbation result in a significant change in NBEAL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and NBEAL2 expression is quantified. Does this perturbation result in a significant change in NBEAL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TNFRSF10B. Does perturbing DDOST lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TNFRSF10B. Does perturbing DDOST lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HMGCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HMGCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GLG1. Does perturbing TMEM167A lead to a significant change in GLG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GLG1. Does perturbing TMEM167A lead to a significant change in GLG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2740,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Does this perturbation cause a significant change in DUSP21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Does this perturbation cause a significant change in DUSP21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1213,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and JARID2 expression is observed. Does this perturbation lead to a significant difference in JARID2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and JARID2 expression is observed. Does this perturbation lead to a significant difference in JARID2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
608,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor PBDC1 expression. Decide whether this perturbation leads to a significant alteration in PBDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor PBDC1 expression. Decide whether this perturbation leads to a significant alteration in PBDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of MYH7B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of MYH7B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and SDF4 expression is quantified. Does this perturbation result in a significant change in SDF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and SDF4 expression is quantified. Does this perturbation result in a significant change in SDF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of NAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of NAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CTC-550B14.7. Does perturbing DHDDS lead to a significant change in CTC-550B14.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CTC-550B14.7. Does perturbing DHDDS lead to a significant change in CTC-550B14.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1090,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Does this perturbation cause a significant change in RP11-328J2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Does this perturbation cause a significant change in RP11-328J2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3650,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Does this perturbation cause a significant change in KCNJ13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Does this perturbation cause a significant change in KCNJ13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Determine whether WDR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Determine whether WDR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1798,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor PKDCC expression. Decide whether this perturbation leads to a significant alteration in PKDCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor PKDCC expression. Decide whether this perturbation leads to a significant alteration in PKDCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDKN2C. Does perturbing HSD17B12 lead to a significant change in CDKN2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDKN2C. Does perturbing HSD17B12 lead to a significant change in CDKN2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EXOC3L2 expression is measured. Determine whether EXOC3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EXOC3L2 expression is measured. Determine whether EXOC3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4810,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Does this perturbation cause a significant change in MBNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Does this perturbation cause a significant change in MBNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Determine whether POU2F2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Determine whether POU2F2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2920,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Does this perturbation cause a significant change in AC007038.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Does this perturbation cause a significant change in AC007038.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2910,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Does this perturbation cause a significant change in AFF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Does this perturbation cause a significant change in AFF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ANXA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ANXA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and STARD9 expression is measured. Determine whether STARD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and STARD9 expression is measured. Determine whether STARD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of PRRC2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of PRRC2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RP11-24F11.2. Does this perturbation cause a significant change in RP11-24F11.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RP11-24F11.2. Does this perturbation cause a significant change in RP11-24F11.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of HOTAIRM1. Does this perturbation cause a significant change in HOTAIRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of HOTAIRM1. Does this perturbation cause a significant change in HOTAIRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and NXF1 expression is measured. Determine whether NXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and NXF1 expression is measured. Determine whether NXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4460,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Does this perturbation cause a significant change in NAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Does this perturbation cause a significant change in NAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2320,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Does this perturbation cause a significant change in H3F3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Does this perturbation cause a significant change in H3F3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4948,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2393,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and RP11-254F7.4 expression is observed. Does this perturbation lead to a significant difference in RP11-254F7.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and RP11-254F7.4 expression is observed. Does this perturbation lead to a significant difference in RP11-254F7.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ARHGAP6. Does perturbing SLC35B1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ARHGAP6. Does perturbing SLC35B1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
513,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PDE4D expression is observed. Does this perturbation lead to a significant difference in PDE4D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PDE4D expression is observed. Does this perturbation lead to a significant difference in PDE4D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of BAMBI. Does perturbing QARS lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of BAMBI. Does perturbing QARS lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of PLB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of PLB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and S100A10 expression is quantified. Does this perturbation result in a significant change in S100A10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and S100A10 expression is quantified. Does this perturbation result in a significant change in S100A10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4130,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Does this perturbation cause a significant change in WDR72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Does this perturbation cause a significant change in WDR72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
190,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Does this perturbation cause a significant change in PDE9A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Does this perturbation cause a significant change in PDE9A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is quantified. Does this perturbation result in a significant change in RP11-24F11.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is quantified. Does this perturbation result in a significant change in RP11-24F11.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of NOX5. Does perturbing SRP72 lead to a significant change in NOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of NOX5. Does perturbing SRP72 lead to a significant change in NOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Determine whether PAXBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Determine whether PAXBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
423,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
97,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-141B14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-141B14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Determine whether RP11-685N10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Determine whether RP11-685N10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is quantified. Does this perturbation result in a significant change in RP11-2H8.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is quantified. Does this perturbation result in a significant change in RP11-2H8.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4048,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor SNHG7 expression. Decide whether this perturbation leads to a significant alteration in SNHG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor SNHG7 expression. Decide whether this perturbation leads to a significant alteration in SNHG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AC015987.1 expression is measured. Determine whether AC015987.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AC015987.1 expression is measured. Determine whether AC015987.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Determine whether PIK3R3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Determine whether PIK3R3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2383,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and DKFZP779L1853 expression is observed. Does this perturbation lead to a significant difference in DKFZP779L1853 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and DKFZP779L1853 expression is observed. Does this perturbation lead to a significant difference in DKFZP779L1853 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is quantified. Does this perturbation result in a significant change in RP11-90P5.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is quantified. Does this perturbation result in a significant change in RP11-90P5.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in PBDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in PBDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Determine whether ARHGAP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Determine whether ARHGAP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and HLA-AS1 expression is measured. Determine whether HLA-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and HLA-AS1 expression is measured. Determine whether HLA-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4880,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of WARS is measured. Does this perturbation cause a significant change in WARS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of WARS is measured. Does this perturbation cause a significant change in WARS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of GMEB1. Does this perturbation cause a significant change in GMEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of GMEB1. Does this perturbation cause a significant change in GMEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of BIRC5. Does this perturbation cause a significant change in BIRC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of BIRC5. Does this perturbation cause a significant change in BIRC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of RP11-445H22.3. Does this perturbation cause a significant change in RP11-445H22.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of RP11-445H22.3. Does this perturbation cause a significant change in RP11-445H22.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of NAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of NAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of F2RL2. Does this perturbation cause a significant change in F2RL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of F2RL2. Does this perturbation cause a significant change in F2RL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3523,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TSPAN33 expression is observed. Does this perturbation lead to a significant difference in TSPAN33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TSPAN33 expression is observed. Does this perturbation lead to a significant difference in TSPAN33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and MORC2-AS1 expression is quantified. Does this perturbation result in a significant change in MORC2-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and MORC2-AS1 expression is quantified. Does this perturbation result in a significant change in MORC2-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and EIF4B expression is quantified. Does this perturbation result in a significant change in EIF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and EIF4B expression is quantified. Does this perturbation result in a significant change in EIF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of AC079466.1. Does this perturbation cause a significant change in AC079466.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of AC079466.1. Does this perturbation cause a significant change in AC079466.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZMYND8. Does perturbing SEL1L lead to a significant change in ZMYND8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZMYND8. Does perturbing SEL1L lead to a significant change in ZMYND8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and ATF7IP2 expression is quantified. Does this perturbation result in a significant change in ATF7IP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and ATF7IP2 expression is quantified. Does this perturbation result in a significant change in ATF7IP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1490,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Does this perturbation cause a significant change in RP11-24F11.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Does this perturbation cause a significant change in RP11-24F11.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of DNTTIP2. Does perturbing TIMM23 lead to a significant change in DNTTIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of DNTTIP2. Does perturbing TIMM23 lead to a significant change in DNTTIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1320,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Does this perturbation cause a significant change in NPDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Does this perturbation cause a significant change in NPDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Determine whether CTD-2521M24.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Determine whether CTD-2521M24.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Determine whether RDH10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Determine whether RDH10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RASGRP2. Does this perturbation cause a significant change in RASGRP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RASGRP2. Does this perturbation cause a significant change in RASGRP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and NOSTRIN expression is measured. Determine whether NOSTRIN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and NOSTRIN expression is measured. Determine whether NOSTRIN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in RP11-434H6.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in RP11-434H6.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
243,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and UHRF1BP1L expression is observed. Does this perturbation lead to a significant difference in UHRF1BP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and UHRF1BP1L expression is observed. Does this perturbation lead to a significant difference in UHRF1BP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EPB42 expression is quantified. Does this perturbation result in a significant change in EPB42 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EPB42 expression is quantified. Does this perturbation result in a significant change in EPB42 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of GPRC5C. Does this perturbation cause a significant change in GPRC5C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of GPRC5C. Does this perturbation cause a significant change in GPRC5C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of AC015987.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of AC015987.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4673,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and H1FX expression is observed. Does this perturbation lead to a significant difference in H1FX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and H1FX expression is observed. Does this perturbation lead to a significant difference in H1FX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
688,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ARSA expression. Decide whether this perturbation leads to a significant alteration in ARSA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ARSA expression. Decide whether this perturbation leads to a significant alteration in ARSA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is measured. Determine whether GS1-166A23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is measured. Determine whether GS1-166A23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
280,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Does this perturbation cause a significant change in CDRT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Does this perturbation cause a significant change in CDRT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and C12orf44 expression is measured. Determine whether C12orf44 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and C12orf44 expression is measured. Determine whether C12orf44 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PDE3B expression is quantified. Does this perturbation result in a significant change in PDE3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PDE3B expression is quantified. Does this perturbation result in a significant change in PDE3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of STARD9. Does perturbing COPZ1 lead to a significant change in STARD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of STARD9. Does perturbing COPZ1 lead to a significant change in STARD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4198,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor CTD-2020K17.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2020K17.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor CTD-2020K17.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2020K17.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Determine whether SPCS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Determine whether SPCS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3790,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Does this perturbation cause a significant change in POLR2J3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Does this perturbation cause a significant change in POLR2J3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
790,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Does this perturbation cause a significant change in REST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Does this perturbation cause a significant change in REST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SIGLEC6. Does perturbing PSMD4 lead to a significant change in SIGLEC6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SIGLEC6. Does perturbing PSMD4 lead to a significant change in SIGLEC6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of RP11-61E11.1. Does this perturbation cause a significant change in RP11-61E11.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of RP11-61E11.1. Does this perturbation cause a significant change in RP11-61E11.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
533,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and IRF7 expression is observed. Does this perturbation lead to a significant difference in IRF7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and IRF7 expression is observed. Does this perturbation lead to a significant difference in IRF7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of MORF4L2. Does perturbing SEC63 lead to a significant change in MORF4L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of MORF4L2. Does perturbing SEC63 lead to a significant change in MORF4L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2938,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-227G15.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-227G15.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-227G15.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-227G15.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of AC005540.3. Does perturbing FECH lead to a significant change in AC005540.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of AC005540.3. Does perturbing FECH lead to a significant change in AC005540.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-95O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-95O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
488,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2968,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CPQ expression. Decide whether this perturbation leads to a significant alteration in CPQ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CPQ expression. Decide whether this perturbation leads to a significant alteration in CPQ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2928,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AC007038.7 expression. Decide whether this perturbation leads to a significant alteration in AC007038.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AC007038.7 expression. Decide whether this perturbation leads to a significant alteration in AC007038.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5113,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and GATA2 expression is observed. Does this perturbation lead to a significant difference in GATA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and GATA2 expression is observed. Does this perturbation lead to a significant difference in GATA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of LRIF1. Does this perturbation cause a significant change in LRIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of LRIF1. Does this perturbation cause a significant change in LRIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and NUFIP2 expression is measured. Determine whether NUFIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and NUFIP2 expression is measured. Determine whether NUFIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PTAR1 expression is measured. Determine whether PTAR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PTAR1 expression is measured. Determine whether PTAR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3350,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Does this perturbation cause a significant change in EXOC3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Does this perturbation cause a significant change in EXOC3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PAXBP1. Does this perturbation cause a significant change in PAXBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PAXBP1. Does this perturbation cause a significant change in PAXBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CD83. Does this perturbation cause a significant change in CD83 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CD83. Does this perturbation cause a significant change in CD83 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DUT. Does perturbing OST4 lead to a significant change in DUT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DUT. Does perturbing OST4 lead to a significant change in DUT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CMTM6. Does perturbing CARS lead to a significant change in CMTM6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CMTM6. Does perturbing CARS lead to a significant change in CMTM6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ATXN7L3B expression is measured. Determine whether ATXN7L3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ATXN7L3B expression is measured. Determine whether ATXN7L3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-328J2.1. Does this perturbation cause a significant change in RP11-328J2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-328J2.1. Does this perturbation cause a significant change in RP11-328J2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-863K10.7 expression is quantified. Does this perturbation result in a significant change in RP11-863K10.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-863K10.7 expression is quantified. Does this perturbation result in a significant change in RP11-863K10.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ANKLE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ANKLE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1143,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SP100 expression is observed. Does this perturbation lead to a significant difference in SP100 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SP100 expression is observed. Does this perturbation lead to a significant difference in SP100 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3893,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ACRV1 expression is observed. Does this perturbation lead to a significant difference in ACRV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ACRV1 expression is observed. Does this perturbation lead to a significant difference in ACRV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4098,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor DSC2 expression. Decide whether this perturbation leads to a significant alteration in DSC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor DSC2 expression. Decide whether this perturbation leads to a significant alteration in DSC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4660,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Does this perturbation cause a significant change in LINC01137 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Does this perturbation cause a significant change in LINC01137 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of HLTF. Does perturbing GBF1 lead to a significant change in HLTF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of HLTF. Does perturbing GBF1 lead to a significant change in HLTF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of RBM12B-AS1. Does perturbing GBF1 lead to a significant change in RBM12B-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of RBM12B-AS1. Does perturbing GBF1 lead to a significant change in RBM12B-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ANPEP expression is quantified. Does this perturbation result in a significant change in ANPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ANPEP expression is quantified. Does this perturbation result in a significant change in ANPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4990,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Does this perturbation cause a significant change in ZCCHC11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Does this perturbation cause a significant change in ZCCHC11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of NINJ2. Does this perturbation cause a significant change in NINJ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of NINJ2. Does this perturbation cause a significant change in NINJ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EIF3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EIF3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3420,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SIGLEC6 expression is measured. Determine whether SIGLEC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SIGLEC6 expression is measured. Determine whether SIGLEC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2503,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and UFD1L expression is observed. Does this perturbation lead to a significant difference in UFD1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and UFD1L expression is observed. Does this perturbation lead to a significant difference in UFD1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of RPL39. Does this perturbation cause a significant change in RPL39 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of RPL39. Does this perturbation cause a significant change in RPL39 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2280,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
17,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SLC37A1. Does this perturbation cause a significant change in SLC37A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SLC37A1. Does this perturbation cause a significant change in SLC37A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Determine whether CCRL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Determine whether CCRL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ROBO1 expression is measured. Determine whether ROBO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ROBO1 expression is measured. Determine whether ROBO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
23,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SIGLEC6. Does this perturbation cause a significant change in SIGLEC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SIGLEC6. Does this perturbation cause a significant change in SIGLEC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and CASP8 expression is measured. Determine whether CASP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and CASP8 expression is measured. Determine whether CASP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and TGOLN2 expression is measured. Determine whether TGOLN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and TGOLN2 expression is measured. Determine whether TGOLN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2498,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor CD58 expression. Decide whether this perturbation leads to a significant alteration in CD58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor CD58 expression. Decide whether this perturbation leads to a significant alteration in CD58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
620,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Does this perturbation cause a significant change in SAMM50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Does this perturbation cause a significant change in SAMM50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of OXLD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of OXLD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of VAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of VAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in EIF4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in EIF4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of NPAT. Does perturbing PSMD4 lead to a significant change in NPAT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of NPAT. Does perturbing PSMD4 lead to a significant change in NPAT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PIK3IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PIK3IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3640,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Does this perturbation cause a significant change in RP11-3D4.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Does this perturbation cause a significant change in RP11-3D4.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-789C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-789C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
460,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Does this perturbation cause a significant change in ERV3-1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Does this perturbation cause a significant change in ERV3-1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of TOB2. Does perturbing IDH3A lead to a significant change in TOB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of TOB2. Does perturbing IDH3A lead to a significant change in TOB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of MORC2-AS1. Does perturbing FARSB lead to a significant change in MORC2-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of MORC2-AS1. Does perturbing FARSB lead to a significant change in MORC2-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2513,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and RBM12B-AS1 expression is observed. Does this perturbation lead to a significant difference in RBM12B-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and RBM12B-AS1 expression is observed. Does this perturbation lead to a significant difference in RBM12B-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Determine whether KIAA1731 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Determine whether KIAA1731 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ADAMTS10. Does perturbing IARS2 lead to a significant change in ADAMTS10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ADAMTS10. Does perturbing IARS2 lead to a significant change in ADAMTS10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and HLA-E expression is quantified. Does this perturbation result in a significant change in HLA-E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and HLA-E expression is quantified. Does this perturbation result in a significant change in HLA-E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1710,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Does this perturbation cause a significant change in EPB42 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Does this perturbation cause a significant change in EPB42 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2043,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of MBNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of MBNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is measured. Determine whether HIST1H2BC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is measured. Determine whether HIST1H2BC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3070,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Does this perturbation cause a significant change in PIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Does this perturbation cause a significant change in PIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of GSN. Does perturbing TTI1 lead to a significant change in GSN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of GSN. Does perturbing TTI1 lead to a significant change in GSN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3048,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor C10orf32 expression. Decide whether this perturbation leads to a significant alteration in C10orf32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor C10orf32 expression. Decide whether this perturbation leads to a significant alteration in C10orf32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4353,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ANKRD10 expression is observed. Does this perturbation lead to a significant difference in ANKRD10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ANKRD10 expression is observed. Does this perturbation lead to a significant difference in ANKRD10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in NOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in NOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Determine whether PRRC2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Determine whether PRRC2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
390,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Does this perturbation cause a significant change in GDF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Does this perturbation cause a significant change in GDF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
69,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RIOK3 expression is measured. Determine whether RIOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RIOK3 expression is measured. Determine whether RIOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4293,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1718,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EPB42 expression. Decide whether this perturbation leads to a significant alteration in EPB42 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EPB42 expression. Decide whether this perturbation leads to a significant alteration in EPB42 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of KLK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of KLK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of RP11-430H10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of RP11-430H10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP6. Does perturbing KCTD16 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP6. Does perturbing KCTD16 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Determine whether C12orf44 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Determine whether C12orf44 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Determine whether DUSP21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Determine whether DUSP21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Determine whether P4HB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Determine whether P4HB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RP11-157D23.2 expression is quantified. Does this perturbation result in a significant change in RP11-157D23.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RP11-157D23.2 expression is quantified. Does this perturbation result in a significant change in RP11-157D23.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in CTD-2001C12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in CTD-2001C12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4230,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Does this perturbation cause a significant change in RP11-666A20.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Does this perturbation cause a significant change in RP11-666A20.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of C12orf44. Does perturbing SEL1L lead to a significant change in C12orf44 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of C12orf44. Does perturbing SEL1L lead to a significant change in C12orf44 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and HPCAL1 expression is measured. Determine whether HPCAL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and HPCAL1 expression is measured. Determine whether HPCAL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3518,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and WDR3 expression is quantified. Does this perturbation result in a significant change in WDR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and WDR3 expression is quantified. Does this perturbation result in a significant change in WDR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and THBS1 expression is measured. Determine whether THBS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and THBS1 expression is measured. Determine whether THBS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AFF1 expression is measured. Determine whether AFF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AFF1 expression is measured. Determine whether AFF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ACRV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ACRV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of FAM114A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of FAM114A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of THBS1. Does perturbing P4HB lead to a significant change in THBS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of THBS1. Does perturbing P4HB lead to a significant change in THBS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2538,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ANKRD33. Does this perturbation cause a significant change in ANKRD33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ANKRD33. Does this perturbation cause a significant change in ANKRD33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and PLB1 expression is quantified. Does this perturbation result in a significant change in PLB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and PLB1 expression is quantified. Does this perturbation result in a significant change in PLB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
54,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of C6orf48. Does this perturbation cause a significant change in C6orf48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of C6orf48. Does this perturbation cause a significant change in C6orf48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and TSNAXIP1 expression is measured. Determine whether TSNAXIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and TSNAXIP1 expression is measured. Determine whether TSNAXIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of KANSL1L. Does this perturbation cause a significant change in KANSL1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of KANSL1L. Does this perturbation cause a significant change in KANSL1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
30,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Does this perturbation cause a significant change in CASP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Does this perturbation cause a significant change in CASP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ACE expression is quantified. Does this perturbation result in a significant change in ACE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ACE expression is quantified. Does this perturbation result in a significant change in ACE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-363D14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-363D14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of HIST1H2AC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of HIST1H2AC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of PLB1. Does perturbing TMED2 lead to a significant change in PLB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of PLB1. Does perturbing TMED2 lead to a significant change in PLB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in RP11-3D4.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in RP11-3D4.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of PHF21A. Does perturbing DDOST lead to a significant change in PHF21A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of PHF21A. Does perturbing DDOST lead to a significant change in PHF21A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1760,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Does this perturbation cause a significant change in C12orf23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Does this perturbation cause a significant change in C12orf23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of SERPINH1. Does this perturbation cause a significant change in SERPINH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of SERPINH1. Does this perturbation cause a significant change in SERPINH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and PKDCC expression is measured. Determine whether PKDCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and PKDCC expression is measured. Determine whether PKDCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4323,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and NOSTRIN expression is observed. Does this perturbation lead to a significant difference in NOSTRIN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and NOSTRIN expression is observed. Does this perturbation lead to a significant difference in NOSTRIN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Determine whether CTSF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Determine whether CTSF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in C9orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in C9orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and BACH2 expression is measured. Determine whether BACH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and BACH2 expression is measured. Determine whether BACH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KIAA1586 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KIAA1586 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Determine whether HLA-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Determine whether HLA-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ATP5EP2. Does this perturbation cause a significant change in ATP5EP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ATP5EP2. Does this perturbation cause a significant change in ATP5EP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2060,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Does this perturbation cause a significant change in RTN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Does this perturbation cause a significant change in RTN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDK13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDK13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4800,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Does this perturbation cause a significant change in EIF3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Does this perturbation cause a significant change in EIF3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and WARS expression is quantified. Does this perturbation result in a significant change in WARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and WARS expression is quantified. Does this perturbation result in a significant change in WARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of JUND. Does this perturbation cause a significant change in JUND expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of JUND. Does this perturbation cause a significant change in JUND expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
143,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RDH10 expression is observed. Does this perturbation lead to a significant difference in RDH10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RDH10 expression is observed. Does this perturbation lead to a significant difference in RDH10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
85,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in PHF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in PHF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2680,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Does this perturbation cause a significant change in KCTD19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Does this perturbation cause a significant change in KCTD19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3340,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Does this perturbation cause a significant change in SIGLEC6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Does this perturbation cause a significant change in SIGLEC6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Determine whether RP11-423O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Determine whether RP11-423O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1260,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Does this perturbation cause a significant change in HOTAIRM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Does this perturbation cause a significant change in HOTAIRM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
883,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and GATA3 expression is observed. Does this perturbation lead to a significant difference in GATA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and GATA3 expression is observed. Does this perturbation lead to a significant difference in GATA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Determine whether UHMK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Determine whether UHMK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3580,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Does this perturbation cause a significant change in RP3-465N24.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Does this perturbation cause a significant change in RP3-465N24.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
43,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and LPAR5 expression is observed. Does this perturbation lead to a significant difference in LPAR5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and LPAR5 expression is observed. Does this perturbation lead to a significant difference in LPAR5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4828,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3828,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor OBSCN expression. Decide whether this perturbation leads to a significant alteration in OBSCN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor OBSCN expression. Decide whether this perturbation leads to a significant alteration in OBSCN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1310,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ZNF678. Does perturbing STT3A lead to a significant change in ZNF678 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ZNF678. Does perturbing STT3A lead to a significant change in ZNF678 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of OBSCN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of OBSCN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of SPAST. Does perturbing SEC61B lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of SPAST. Does perturbing SEC61B lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SDF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SDF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4340,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Does this perturbation cause a significant change in HIST1H1D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Does this perturbation cause a significant change in HIST1H1D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EPB42 expression is measured. Determine whether EPB42 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EPB42 expression is measured. Determine whether EPB42 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of IL13RA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of IL13RA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Determine whether IRF7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Determine whether IRF7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4743,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PAXBP1 expression is observed. Does this perturbation lead to a significant difference in PAXBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PAXBP1 expression is observed. Does this perturbation lead to a significant difference in PAXBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3630,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Does this perturbation cause a significant change in SOBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Does this perturbation cause a significant change in SOBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and HAGH expression is measured. Determine whether HAGH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and HAGH expression is measured. Determine whether HAGH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Determine whether RP11-390B4.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Determine whether RP11-390B4.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2583,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and KIF4A expression is observed. Does this perturbation lead to a significant difference in KIF4A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and KIF4A expression is observed. Does this perturbation lead to a significant difference in KIF4A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in TACC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in TACC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of H1FX. Does perturbing EIF2B3 lead to a significant change in H1FX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of H1FX. Does perturbing EIF2B3 lead to a significant change in H1FX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP11-2H8.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP11-2H8.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and KANSL1L expression is measured. Determine whether KANSL1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and KANSL1L expression is measured. Determine whether KANSL1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of RP11-242O24.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of RP11-242O24.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2708,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RAI14 expression. Decide whether this perturbation leads to a significant alteration in RAI14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RAI14 expression. Decide whether this perturbation leads to a significant alteration in RAI14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of BACH2. Does this perturbation cause a significant change in BACH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of BACH2. Does this perturbation cause a significant change in BACH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3608,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and CTSF expression is quantified. Does this perturbation result in a significant change in CTSF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and CTSF expression is quantified. Does this perturbation result in a significant change in CTSF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in PPP4R2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in PPP4R2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3283,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and AC018878.3 expression is observed. Does this perturbation lead to a significant difference in AC018878.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and AC018878.3 expression is observed. Does this perturbation lead to a significant difference in AC018878.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1800,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Does this perturbation cause a significant change in LTBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Does this perturbation cause a significant change in LTBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of KLK1. Does this perturbation cause a significant change in KLK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of KLK1. Does this perturbation cause a significant change in KLK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RNF8 expression is measured. Determine whether RNF8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RNF8 expression is measured. Determine whether RNF8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3510,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
78,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor CEBPG expression. Decide whether this perturbation leads to a significant alteration in CEBPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor CEBPG expression. Decide whether this perturbation leads to a significant alteration in CEBPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of RP11-247A12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of RP11-247A12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of SMCO1. Does this perturbation cause a significant change in SMCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of SMCO1. Does this perturbation cause a significant change in SMCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ZFP36L2. Does perturbing KCTD16 lead to a significant change in ZFP36L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ZFP36L2. Does perturbing KCTD16 lead to a significant change in ZFP36L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of RP11-573D15.9. Does this perturbation cause a significant change in RP11-573D15.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of RP11-573D15.9. Does this perturbation cause a significant change in RP11-573D15.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2398,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor RP11-254F7.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-254F7.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor RP11-254F7.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-254F7.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1283,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2683,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and KCTD19 expression is observed. Does this perturbation lead to a significant difference in KCTD19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and KCTD19 expression is observed. Does this perturbation lead to a significant difference in KCTD19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1530,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Does this perturbation cause a significant change in C12orf44 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Does this perturbation cause a significant change in C12orf44 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4403,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Determine whether C1GALT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Determine whether C1GALT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4893,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and KIAA1731 expression is observed. Does this perturbation lead to a significant difference in KIAA1731 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and KIAA1731 expression is observed. Does this perturbation lead to a significant difference in KIAA1731 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EIF3A expression is quantified. Does this perturbation result in a significant change in EIF3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EIF3A expression is quantified. Does this perturbation result in a significant change in EIF3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
903,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and PRRC2B expression is observed. Does this perturbation lead to a significant difference in PRRC2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and PRRC2B expression is observed. Does this perturbation lead to a significant difference in PRRC2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of QSER1. Does perturbing EIF2B2 lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of QSER1. Does perturbing EIF2B2 lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Determine whether BOLA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Determine whether BOLA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EGLN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EGLN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4788,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PDE3B expression. Decide whether this perturbation leads to a significant alteration in PDE3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PDE3B expression. Decide whether this perturbation leads to a significant alteration in PDE3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1998,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of KLK1. Does perturbing DDIT3 lead to a significant change in KLK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of KLK1. Does perturbing DDIT3 lead to a significant change in KLK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."