[
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL41 and then measure expression of MRPL41. Does this perturbation cause a significant change in MRPL41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL41 and then measure expression of MRPL41. Does this perturbation cause a significant change in MRPL41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27754
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR1D and examine the expression of NMU. Does perturbing POLR1D lead to a significant change in NMU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR1D and examine the expression of NMU. Does perturbing POLR1D lead to a significant change in NMU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36551
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PET117 is perturbed and NAT14 expression is measured. Determine whether NAT14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PET117 is perturbed and NAT14 expression is measured. Determine whether NAT14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34889
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which WDFY3 is perturbed and ATP1A1 expression is observed. Does this perturbation lead to a significant difference in ATP1A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which WDFY3 is perturbed and ATP1A1 expression is observed. Does this perturbation lead to a significant difference in ATP1A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59473
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BNIP1 is perturbed and TYMS expression is quantified. Does this perturbation result in a significant change in TYMS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BNIP1 is perturbed and TYMS expression is quantified. Does this perturbation result in a significant change in TYMS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3712
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SIN3A is perturbed and TPM2 expression is quantified. Does this perturbation result in a significant change in TPM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SIN3A is perturbed and TPM2 expression is quantified. Does this perturbation result in a significant change in TPM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48342
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP14 is perturbed and the expression of NEDD8 is measured. Determine whether NEDD8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP14 is perturbed and the expression of NEDD8 is measured. Determine whether NEDD8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58256
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK1 and then measure expression of KIF11. Does this perturbation cause a significant change in KIF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK1 and then measure expression of KIF11. Does this perturbation cause a significant change in KIF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6424
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PUF60 is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PUF60 is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40515
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOC3 is perturbed and NUDT12 expression is quantified. Does this perturbation result in a significant change in NUDT12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOC3 is perturbed and NUDT12 expression is quantified. Does this perturbation result in a significant change in NUDT12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15812
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PMPCA is perturbed and MT-ND6 expression is measured. Determine whether MT-ND6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PMPCA is perturbed and MT-ND6 expression is measured. Determine whether MT-ND6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35919
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRB2 is perturbed and BUB1B expression is measured. Determine whether BUB1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRB2 is perturbed and BUB1B expression is measured. Determine whether BUB1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2179
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHAF1A is associated with a significant change in SFR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHAF1A is associated with a significant change in SFR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7165
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLMN is perturbed and PRAF2 expression is measured. Determine whether PRAF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLMN is perturbed and PRAF2 expression is measured. Determine whether PRAF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18019
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TPT1 is perturbed and TPT1 expression is measured. Determine whether TPT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TPT1 is perturbed and TPT1 expression is measured. Determine whether TPT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55399
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMX2 is perturbed and the expression of TMX2 is measured. Does this perturbation cause a significant change in TMX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMX2 is perturbed and the expression of TMX2 is measured. Does this perturbation cause a significant change in TMX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54810
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPS24 and monitor PRIM1 expression. Decide whether this perturbation leads to a significant alteration in PRIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPS24 and monitor PRIM1 expression. Decide whether this perturbation leads to a significant alteration in PRIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45408
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TAF11 is perturbed and TAF11 expression is observed. Does this perturbation lead to a significant difference in TAF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TAF11 is perturbed and TAF11 expression is observed. Does this perturbation lead to a significant difference in TAF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52573
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TWSG1 is associated with a significant change in HAUS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TWSG1 is associated with a significant change in HAUS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56775
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS25 is perturbed and the expression of TNIK is measured. Determine whether TNIK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS25 is perturbed and the expression of TNIK is measured. Determine whether TNIK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28546
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP6 is perturbed and the expression of INSIG1 is measured. Does this perturbation cause a significant change in INSIG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP6 is perturbed and the expression of INSIG1 is measured. Does this perturbation cause a significant change in INSIG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7570
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NMD3 is perturbed and the expression of ACTA2 is measured. Determine whether ACTA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NMD3 is perturbed and the expression of ACTA2 is measured. Determine whether ACTA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31656
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLE1 and examine the expression of NASP. Does perturbing GLE1 lead to a significant change in NASP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLE1 and examine the expression of NASP. Does perturbing GLE1 lead to a significant change in NASP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17961
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF38A is associated with a significant change in NAGLU expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF38A is associated with a significant change in NAGLU expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38795
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPTLC1 is associated with a significant change in CDC25A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPTLC1 is associated with a significant change in CDC25A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50865
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFB4 and then measure expression of WDR45. Does this perturbation cause a significant change in WDR45 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFB4 and then measure expression of WDR45. Does this perturbation cause a significant change in WDR45 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30804
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNOT11 and then measure expression of EMP3. Does this perturbation cause a significant change in EMP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNOT11 and then measure expression of EMP3. Does this perturbation cause a significant change in EMP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8324
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and TLNRD1 expression is observed. Does this perturbation lead to a significant difference in TLNRD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and TLNRD1 expression is observed. Does this perturbation lead to a significant difference in TLNRD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56303
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS7 and examine the expression of AURKA. Does perturbing INTS7 lead to a significant change in AURKA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS7 and examine the expression of AURKA. Does perturbing INTS7 lead to a significant change in AURKA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22061
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YARS is perturbed and TRIB3 expression is observed. Does this perturbation lead to a significant difference in TRIB3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YARS is perturbed and TRIB3 expression is observed. Does this perturbation lead to a significant difference in TRIB3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60633
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDX54 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDX54 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11648
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL20, does the expression profile of FAAP20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL20, does the expression profile of FAAP20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27257
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPAT is perturbed and CCNA2 expression is measured. Determine whether CCNA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPAT is perturbed and CCNA2 expression is measured. Determine whether CCNA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18249
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX30 is associated with a significant change in SLC26A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX30 is associated with a significant change in SLC26A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12125
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSEN2, does the expression profile of PSAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSEN2, does the expression profile of PSAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55927
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHOC2 and then measure expression of TPI1. Does this perturbation cause a significant change in TPI1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHOC2 and then measure expression of TPI1. Does this perturbation cause a significant change in TPI1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48294
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DPAGT1 and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DPAGT1 and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12938
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BTF3 is perturbed and SELENOM expression is quantified. Does this perturbation result in a significant change in SELENOM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BTF3 is perturbed and SELENOM expression is quantified. Does this perturbation result in a significant change in SELENOM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4122
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SSBP3 is perturbed and SSBP3 expression is quantified. Does this perturbation result in a significant change in SSBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SSBP3 is perturbed and SSBP3 expression is quantified. Does this perturbation result in a significant change in SSBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51632
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PEF1 is associated with a significant change in RBM24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PEF1 is associated with a significant change in RBM24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34755
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb VHL and monitor FUT11 expression. Decide whether this perturbation leads to a significant alteration in FUT11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb VHL and monitor FUT11 expression. Decide whether this perturbation leads to a significant alteration in FUT11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58918
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC17 and examine the expression of ALDH16A1. Does perturbing DNAJC17 lead to a significant change in ALDH16A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC17 and examine the expression of ALDH16A1. Does perturbing DNAJC17 lead to a significant change in ALDH16A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12591
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LTV1 is perturbed and BUB1B expression is quantified. Does this perturbation result in a significant change in BUB1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LTV1 is perturbed and BUB1B expression is quantified. Does this perturbation result in a significant change in BUB1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24422
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYS1 is perturbed and SYS1 expression is observed. Does this perturbation lead to a significant difference in SYS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYS1 is perturbed and SYS1 expression is observed. Does this perturbation lead to a significant difference in SYS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52383
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GSPT1 is perturbed and DDIT4 expression is observed. Does this perturbation lead to a significant difference in DDIT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GSPT1 is perturbed and DDIT4 expression is observed. Does this perturbation lead to a significant difference in DDIT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18733
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2K, does the expression profile of NCAPH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2K, does the expression profile of NCAPH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36887
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUDC is associated with a significant change in NUDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUDC is associated with a significant change in NUDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32795
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HJURP and monitor FBXO32 expression. Decide whether this perturbation leads to a significant alteration in FBXO32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HJURP and monitor FBXO32 expression. Decide whether this perturbation leads to a significant alteration in FBXO32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20098
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AIFM1 is perturbed and the expression of PCNX4 is measured. Does this perturbation cause a significant change in PCNX4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AIFM1 is perturbed and the expression of PCNX4 is measured. Does this perturbation cause a significant change in PCNX4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1030
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RIOK2 is associated with a significant change in DLGAP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RIOK2 is associated with a significant change in DLGAP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42495
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPW and examine the expression of MARCKSL1. Does perturbing CENPW lead to a significant change in MARCKSL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPW and examine the expression of MARCKSL1. Does perturbing CENPW lead to a significant change in MARCKSL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6971
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLI4 is associated with a significant change in RRN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLI4 is associated with a significant change in RRN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17985
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPN2 is perturbed and RPN2 expression is observed. Does this perturbation lead to a significant difference in RPN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPN2 is perturbed and RPN2 expression is observed. Does this perturbation lead to a significant difference in RPN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44733
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VPS35 is perturbed and VPS35 expression is quantified. Does this perturbation result in a significant change in VPS35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VPS35 is perturbed and VPS35 expression is quantified. Does this perturbation result in a significant change in VPS35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59132
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NUDT15 is perturbed and SPP1 expression is measured. Determine whether SPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NUDT15 is perturbed and SPP1 expression is measured. Determine whether SPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32869
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SASS6 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SASS6 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46858
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAA38, does the expression profile of STMN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAA38, does the expression profile of STMN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29657
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD3 and examine the expression of ABHD8. Does perturbing CHCHD3 lead to a significant change in ABHD8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD3 and examine the expression of ABHD8. Does perturbing CHCHD3 lead to a significant change in ABHD8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7281
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4G1 is perturbed and the expression of TM4SF1 is measured. Does this perturbation cause a significant change in TM4SF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4G1 is perturbed and the expression of TM4SF1 is measured. Does this perturbation cause a significant change in TM4SF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14740
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL41 is perturbed and PIGG expression is observed. Does this perturbation lead to a significant difference in PIGG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL41 is perturbed and PIGG expression is observed. Does this perturbation lead to a significant difference in PIGG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44423
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRC1, does the expression profile of PRC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRC1, does the expression profile of PRC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38257
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GFM1 is perturbed and the expression of CDC20 is measured. Does this perturbation cause a significant change in CDC20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GFM1 is perturbed and the expression of CDC20 is measured. Does this perturbation cause a significant change in CDC20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17720
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF4A3 and examine the expression of CIT. Does perturbing EIF4A3 lead to a significant change in CIT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF4A3 and examine the expression of CIT. Does perturbing EIF4A3 lead to a significant change in CIT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14641
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL13 is perturbed and the expression of PPRC1 is measured. Does this perturbation cause a significant change in PPRC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL13 is perturbed and the expression of PPRC1 is measured. Does this perturbation cause a significant change in PPRC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27000
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2H4 and then measure expression of PLK4. Does this perturbation cause a significant change in PLK4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2H4 and then measure expression of PLK4. Does this perturbation cause a significant change in PLK4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19074
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL22 is perturbed and the expression of MT-ND3 is measured. Does this perturbation cause a significant change in MT-ND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL22 is perturbed and the expression of MT-ND3 is measured. Does this perturbation cause a significant change in MT-ND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27320
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SBNO1 and examine the expression of EIF4B. Does perturbing SBNO1 lead to a significant change in EIF4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SBNO1 and examine the expression of EIF4B. Does perturbing SBNO1 lead to a significant change in EIF4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46901
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETD2 and then measure expression of PLPP3. Does this perturbation cause a significant change in PLPP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETD2 and then measure expression of PLPP3. Does this perturbation cause a significant change in PLPP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47734
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS29 is perturbed and the expression of IL1B is measured. Determine whether IL1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS29 is perturbed and the expression of IL1B is measured. Determine whether IL1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59096
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF207 and examine the expression of ZNF207. Does perturbing ZNF207 lead to a significant change in ZNF207 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF207 and examine the expression of ZNF207. Does perturbing ZNF207 lead to a significant change in ZNF207 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61471
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HPS5 is perturbed and HPS5 expression is observed. Does this perturbation lead to a significant difference in HPS5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HPS5 is perturbed and HPS5 expression is observed. Does this perturbation lead to a significant difference in HPS5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20613
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of ZNF714 is measured. Determine whether ZNF714 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of ZNF714 is measured. Determine whether ZNF714 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24716
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX21, does the expression profile of CLSPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX21, does the expression profile of CLSPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11327
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CPSF2 is perturbed and GBP3 expression is observed. Does this perturbation lead to a significant difference in GBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CPSF2 is perturbed and GBP3 expression is observed. Does this perturbation lead to a significant difference in GBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9593
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NEMF and monitor GDF6 expression. Decide whether this perturbation leads to a significant alteration in GDF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEMF and monitor GDF6 expression. Decide whether this perturbation leads to a significant alteration in GDF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31188
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLE is perturbed and HNRNPD expression is measured. Determine whether HNRNPD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLE is perturbed and HNRNPD expression is measured. Determine whether HNRNPD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36359
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTPBP4 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTPBP4 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19314
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUVBL2 and examine the expression of MCM8. Does perturbing RUVBL2 lead to a significant change in MCM8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUVBL2 and examine the expression of MCM8. Does perturbing RUVBL2 lead to a significant change in MCM8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46461
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THRAP3 is perturbed and RPSA expression is measured. Determine whether RPSA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THRAP3 is perturbed and RPSA expression is measured. Determine whether RPSA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54059
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UTP3 is perturbed and TMEM9B expression is quantified. Does this perturbation result in a significant change in TMEM9B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UTP3 is perturbed and TMEM9B expression is quantified. Does this perturbation result in a significant change in TMEM9B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58652
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPA is perturbed and CCDC28B expression is measured. Determine whether CCDC28B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPA is perturbed and CCDC28B expression is measured. Determine whether CCDC28B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49979
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GRB2 is perturbed and the expression of GRB2 is measured. Determine whether GRB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GRB2 is perturbed and the expression of GRB2 is measured. Determine whether GRB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18586
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS29 is perturbed and VPS29 expression is measured. Determine whether VPS29 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS29 is perturbed and VPS29 expression is measured. Determine whether VPS29 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59079
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PCNX3 and monitor SAE1 expression. Decide whether this perturbation leads to a significant alteration in SAE1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PCNX3 and monitor SAE1 expression. Decide whether this perturbation leads to a significant alteration in SAE1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34428
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AAR2 is perturbed and PLEKHA5 expression is measured. Determine whether PLEKHA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AAR2 is perturbed and PLEKHA5 expression is measured. Determine whether PLEKHA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR92 is perturbed and PRR16 expression is measured. Determine whether PRR16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR92 is perturbed and PRR16 expression is measured. Determine whether PRR16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60199
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PCNA and monitor SPAG5 expression. Decide whether this perturbation leads to a significant alteration in SPAG5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PCNA and monitor SPAG5 expression. Decide whether this perturbation leads to a significant alteration in SPAG5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34388
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPATA5 and then measure expression of GINS1. Does this perturbation cause a significant change in GINS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPATA5 and then measure expression of GINS1. Does this perturbation cause a significant change in GINS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50574
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NPM1 and then measure expression of NPM1. Does this perturbation cause a significant change in NPM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NPM1 and then measure expression of NPM1. Does this perturbation cause a significant change in NPM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32344
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUGT1 and then measure expression of CDCA5. Does this perturbation cause a significant change in CDCA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUGT1 and then measure expression of CDCA5. Does this perturbation cause a significant change in CDCA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52074
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NACA is perturbed and the expression of CDC25B is measured. Does this perturbation cause a significant change in CDC25B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NACA is perturbed and the expression of CDC25B is measured. Does this perturbation cause a significant change in CDC25B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29700
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COA5 is perturbed and COA5 expression is observed. Does this perturbation lead to a significant difference in COA5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COA5 is perturbed and COA5 expression is observed. Does this perturbation lead to a significant difference in COA5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8433
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRPA1 and then measure expression of KIF20A. Does this perturbation cause a significant change in KIF20A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRPA1 and then measure expression of KIF20A. Does this perturbation cause a significant change in KIF20A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49984
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MED6 is perturbed and PRKAR2B expression is measured. Determine whether PRKAR2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MED6 is perturbed and PRKAR2B expression is measured. Determine whether PRKAR2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25799
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR2D and then measure expression of TPP2. Does this perturbation cause a significant change in TPP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR2D and then measure expression of TPP2. Does this perturbation cause a significant change in TPP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36704
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF1AX is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF1AX is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14056
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UXS1 and then measure expression of HINT1. Does this perturbation cause a significant change in HINT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UXS1 and then measure expression of HINT1. Does this perturbation cause a significant change in HINT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58734
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL22 and then measure expression of MT-ATP8. Does this perturbation cause a significant change in MT-ATP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL22 and then measure expression of MT-ATP8. Does this perturbation cause a significant change in MT-ATP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27314
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FKBP9 is perturbed and the expression of USP42 is measured. Does this perturbation cause a significant change in USP42 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FKBP9 is perturbed and the expression of USP42 is measured. Does this perturbation cause a significant change in USP42 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16990
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC3 and examine the expression of PGAM5. Does perturbing PSMC3 lead to a significant change in PGAM5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC3 and examine the expression of PGAM5. Does perturbing PSMC3 lead to a significant change in PGAM5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39551
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC1A5 is perturbed and SLC1A5 expression is measured. Determine whether SLC1A5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC1A5 is perturbed and SLC1A5 expression is measured. Determine whether SLC1A5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48549
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PYROXD1, does the expression profile of TOMM7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PYROXD1, does the expression profile of TOMM7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40627
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPB2 and monitor NMU expression. Decide whether this perturbation leads to a significant alteration in NMU expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPB2 and monitor NMU expression. Decide whether this perturbation leads to a significant alteration in NMU expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8768
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USF2, does the expression profile of DDX17 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USF2, does the expression profile of DDX17 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58187
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHX37 is perturbed and the expression of SLC43A3 is measured. Determine whether SLC43A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHX37 is perturbed and the expression of SLC43A3 is measured. Determine whether SLC43A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12216
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC1A5 and monitor KLF2 expression. Decide whether this perturbation leads to a significant alteration in KLF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC1A5 and monitor KLF2 expression. Decide whether this perturbation leads to a significant alteration in KLF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48568
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS8 is associated with a significant change in PRC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS8 is associated with a significant change in PRC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22105
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BYSL is perturbed and RTKN2 expression is quantified. Does this perturbation result in a significant change in RTKN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BYSL is perturbed and RTKN2 expression is quantified. Does this perturbation result in a significant change in RTKN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4332
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LPIN1 is perturbed and SAPCD2 expression is measured. Determine whether SAPCD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LPIN1 is perturbed and SAPCD2 expression is measured. Determine whether SAPCD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23979
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of THOC7 is associated with a significant change in THOC7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of THOC7 is associated with a significant change in THOC7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54005
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PXN and then measure expression of DANCR. Does this perturbation cause a significant change in DANCR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PXN and then measure expression of DANCR. Does this perturbation cause a significant change in DANCR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40594
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2F1 is associated with a significant change in TMEM63A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2F1 is associated with a significant change in TMEM63A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18925
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPATA5, does the expression profile of BLM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPATA5, does the expression profile of BLM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50557
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ANKRD11 is perturbed and HEBP1 expression is measured. Determine whether HEBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ANKRD11 is perturbed and HEBP1 expression is measured. Determine whether HEBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1519
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, METTL23 is perturbed and the expression of TMEM35B is measured. Determine whether TMEM35B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, METTL23 is perturbed and the expression of TMEM35B is measured. Determine whether TMEM35B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26186
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ADAM10, does the expression profile of SFTA1P indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ADAM10, does the expression profile of SFTA1P indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":797
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COX10 and examine the expression of LIMA1. Does perturbing COX10 lead to a significant change in LIMA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COX10 and examine the expression of LIMA1. Does perturbing COX10 lead to a significant change in LIMA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9181
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STX18 is perturbed and the expression of COL13A1 is measured. Does this perturbation cause a significant change in COL13A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STX18 is perturbed and the expression of COL13A1 is measured. Does this perturbation cause a significant change in COL13A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51900
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPH1 is perturbed and the expression of RBM3 is measured. Determine whether RBM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPH1 is perturbed and the expression of RBM3 is measured. Determine whether RBM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20436
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20896
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2H4 is associated with a significant change in PLK4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2H4 is associated with a significant change in PLK4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19075
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BRD8 and then measure expression of MND1. Does this perturbation cause a significant change in MND1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BRD8 and then measure expression of MND1. Does this perturbation cause a significant change in MND1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3934
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS8, does the expression profile of MCM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS8, does the expression profile of MCM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45797
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2L and examine the expression of MYBBP1A. Does perturbing POLR2L lead to a significant change in MYBBP1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2L and examine the expression of MYBBP1A. Does perturbing POLR2L lead to a significant change in MYBBP1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36921
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TAF7 is perturbed and EEF1AKMT4 expression is observed. Does this perturbation lead to a significant difference in EEF1AKMT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TAF7 is perturbed and EEF1AKMT4 expression is observed. Does this perturbation lead to a significant difference in EEF1AKMT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52853
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MLST8 is perturbed and the expression of MLST8 is measured. Does this perturbation cause a significant change in MLST8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MLST8 is perturbed and the expression of MLST8 is measured. Does this perturbation cause a significant change in MLST8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26550
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS14, does the expression profile of RPIA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS14, does the expression profile of RPIA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28217
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL38 is perturbed and TMED10 expression is measured. Determine whether TMED10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL38 is perturbed and TMED10 expression is measured. Determine whether TMED10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27669
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1CA is perturbed and the expression of PPP1CA is measured. Determine whether PPP1CA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1CA is perturbed and the expression of PPP1CA is measured. Determine whether PPP1CA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37696
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PALB2 is perturbed and the expression of DTL is measured. Does this perturbation cause a significant change in DTL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PALB2 is perturbed and the expression of DTL is measured. Does this perturbation cause a significant change in DTL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34110
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB44 is perturbed and NME4 expression is quantified. Does this perturbation result in a significant change in NME4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB44 is perturbed and NME4 expression is quantified. Does this perturbation result in a significant change in NME4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61052
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF6 is perturbed and EIF6 expression is observed. Does this perturbation lead to a significant difference in EIF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF6 is perturbed and EIF6 expression is observed. Does this perturbation lead to a significant difference in EIF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14893
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb REV3L and monitor RAB27B expression. Decide whether this perturbation leads to a significant alteration in RAB27B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb REV3L and monitor RAB27B expression. Decide whether this perturbation leads to a significant alteration in RAB27B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42108
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LAMTOR1 is perturbed and the expression of GPNMB is measured. Does this perturbation cause a significant change in GPNMB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LAMTOR1 is perturbed and the expression of GPNMB is measured. Does this perturbation cause a significant change in GPNMB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23570
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRC1 is associated with a significant change in CDCA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRC1 is associated with a significant change in CDCA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38275
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUD13 is perturbed and PITRM1 expression is quantified. Does this perturbation result in a significant change in PITRM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUD13 is perturbed and PITRM1 expression is quantified. Does this perturbation result in a significant change in PITRM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4262
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL14 is perturbed and MT-ND3 expression is observed. Does this perturbation lead to a significant difference in MT-ND3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL14 is perturbed and MT-ND3 expression is observed. Does this perturbation lead to a significant difference in MT-ND3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27053
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IST1 is perturbed and SFRP1 expression is quantified. Does this perturbation result in a significant change in SFRP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IST1 is perturbed and SFRP1 expression is quantified. Does this perturbation result in a significant change in SFRP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22362
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CENPK, does the expression profile of TMPO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CENPK, does the expression profile of TMPO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6897
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL16 is perturbed and the expression of MT-ND3 is measured. Does this perturbation cause a significant change in MT-ND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL16 is perturbed and the expression of MT-ND3 is measured. Does this perturbation cause a significant change in MT-ND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27110
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MBD3 and examine the expression of RPL26L1. Does perturbing MBD3 lead to a significant change in RPL26L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MBD3 and examine the expression of RPL26L1. Does perturbing MBD3 lead to a significant change in RPL26L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24851
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOSC3 and examine the expression of ERCC6L. Does perturbing EXOSC3 lead to a significant change in ERCC6L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOSC3 and examine the expression of ERCC6L. Does perturbing EXOSC3 lead to a significant change in ERCC6L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16061
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MBTPS1 and examine the expression of CALR. Does perturbing MBTPS1 lead to a significant change in CALR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MBTPS1 and examine the expression of CALR. Does perturbing MBTPS1 lead to a significant change in CALR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24941
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS27 is associated with a significant change in GPRC5C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS27 is associated with a significant change in GPRC5C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45505
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC4 and then measure expression of MAP1A. Does this perturbation cause a significant change in MAP1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC4 and then measure expression of MAP1A. Does this perturbation cause a significant change in MAP1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39594
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFAF3 is perturbed and IMPDH2 expression is observed. Does this perturbation lead to a significant difference in IMPDH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFAF3 is perturbed and IMPDH2 expression is observed. Does this perturbation lead to a significant difference in IMPDH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30643
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMC4 is perturbed and MCM7 expression is observed. Does this perturbation lead to a significant difference in MCM7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMC4 is perturbed and MCM7 expression is observed. Does this perturbation lead to a significant difference in MCM7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49193
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L1 is perturbed and the expression of ALDH1A3 is measured. Determine whether ALDH1A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L1 is perturbed and the expression of ALDH1A3 is measured. Determine whether ALDH1A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3446
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb U2AF2 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb U2AF2 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56938
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AAMP is perturbed and CEP55 expression is observed. Does this perturbation lead to a significant difference in CEP55 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AAMP is perturbed and CEP55 expression is observed. Does this perturbation lead to a significant difference in CEP55 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL54 is perturbed and the expression of MRPL54 is measured. Determine whether MRPL54 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL54 is perturbed and the expression of MRPL54 is measured. Determine whether MRPL54 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28026
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD14 is perturbed and MAP1A expression is quantified. Does this perturbation result in a significant change in MAP1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD14 is perturbed and MAP1A expression is quantified. Does this perturbation result in a significant change in MAP1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39792
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ACTR2 is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ACTR2 is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":682
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FGFR1OP is perturbed and UBAP2 expression is quantified. Does this perturbation result in a significant change in UBAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FGFR1OP is perturbed and UBAP2 expression is quantified. Does this perturbation result in a significant change in UBAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16942
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM161B is perturbed and the expression of IFT122 is measured. Determine whether IFT122 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM161B is perturbed and the expression of IFT122 is measured. Determine whether IFT122 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54646
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLCC1 is perturbed and AC007336.1 expression is quantified. Does this perturbation result in a significant change in AC007336.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLCC1 is perturbed and AC007336.1 expression is quantified. Does this perturbation result in a significant change in AC007336.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7882
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL51 and then measure expression of NCAPD2. Does this perturbation cause a significant change in NCAPD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL51 and then measure expression of NCAPD2. Does this perturbation cause a significant change in NCAPD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28004
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS19BP1 and examine the expression of KIF20A. Does perturbing RPS19BP1 lead to a significant change in KIF20A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS19BP1 and examine the expression of KIF20A. Does perturbing RPS19BP1 lead to a significant change in KIF20A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45251
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STRAP and examine the expression of PLK4. Does perturbing STRAP lead to a significant change in PLK4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STRAP and examine the expression of PLK4. Does perturbing STRAP lead to a significant change in PLK4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51821
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPZ is perturbed and HIST1H2AH expression is quantified. Does this perturbation result in a significant change in HIST1H2AH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPZ is perturbed and HIST1H2AH expression is quantified. Does this perturbation result in a significant change in HIST1H2AH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6682
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf53 and examine the expression of FOXM1. Does perturbing C19orf53 lead to a significant change in FOXM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf53 and examine the expression of FOXM1. Does perturbing C19orf53 lead to a significant change in FOXM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4461
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPP14 and monitor E2F1 expression. Decide whether this perturbation leads to a significant alteration in E2F1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPP14 and monitor E2F1 expression. Decide whether this perturbation leads to a significant alteration in E2F1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44778
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSEN34 is perturbed and MBOAT7 expression is measured. Determine whether MBOAT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSEN34 is perturbed and MBOAT7 expression is measured. Determine whether MBOAT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55969
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MNAT1 is perturbed and PLK4 expression is measured. Determine whether PLK4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MNAT1 is perturbed and PLK4 expression is measured. Determine whether PLK4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26679
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TAF6 is perturbed and TAF6 expression is observed. Does this perturbation lead to a significant difference in TAF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TAF6 is perturbed and TAF6 expression is observed. Does this perturbation lead to a significant difference in TAF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52803
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED4, does the expression profile of DMKN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED4, does the expression profile of DMKN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25757
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RSRC2 is perturbed and the expression of PAX8-AS1 is measured. Determine whether PAX8-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RSRC2 is perturbed and the expression of PAX8-AS1 is measured. Determine whether PAX8-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46266
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMG1, does the expression profile of SNHG32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMG1, does the expression profile of SNHG32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49277
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCAF1 and examine the expression of ATIC. Does perturbing SCAF1 lead to a significant change in ATIC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCAF1 and examine the expression of ATIC. Does perturbing SCAF1 lead to a significant change in ATIC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46921
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMA2 is perturbed and PIMREG expression is measured. Determine whether PIMREG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMA2 is perturbed and PIMREG expression is measured. Determine whether PIMREG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39149
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPDL1 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPDL1 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50752
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of NASP. Does this perturbation cause a significant change in NASP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of NASP. Does this perturbation cause a significant change in NASP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51804
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RNF113A is perturbed and VSIG10 expression is observed. Does this perturbation lead to a significant difference in VSIG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RNF113A is perturbed and VSIG10 expression is observed. Does this perturbation lead to a significant difference in VSIG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42623
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KANSL3 is perturbed and the expression of GSTCD is measured. Determine whether GSTCD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KANSL3 is perturbed and the expression of GSTCD is measured. Determine whether GSTCD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22616
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPH1, does the expression profile of FBXO5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPH1, does the expression profile of FBXO5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20997
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPRTN is perturbed and NEK9 expression is observed. Does this perturbation lead to a significant difference in NEK9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPRTN is perturbed and NEK9 expression is observed. Does this perturbation lead to a significant difference in NEK9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50833
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDC73 is perturbed and TSPYL2 expression is observed. Does this perturbation lead to a significant difference in TSPYL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDC73 is perturbed and TSPYL2 expression is observed. Does this perturbation lead to a significant difference in TSPYL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6343
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIS18A is perturbed and the expression of MIS18A is measured. Determine whether MIS18A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIS18A is perturbed and the expression of MIS18A is measured. Determine whether MIS18A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26436
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MYSM1 and monitor TMEM120B expression. Decide whether this perturbation leads to a significant alteration in TMEM120B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MYSM1 and monitor TMEM120B expression. Decide whether this perturbation leads to a significant alteration in TMEM120B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29398
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPH2 is perturbed and ACSL4 expression is quantified. Does this perturbation result in a significant change in ACSL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPH2 is perturbed and ACSL4 expression is quantified. Does this perturbation result in a significant change in ACSL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12972
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DESI1 is perturbed and the expression of AP1S1 is measured. Determine whether AP1S1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DESI1 is perturbed and the expression of AP1S1 is measured. Determine whether AP1S1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11866
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD11 and examine the expression of ABHD11. Does perturbing ABHD11 lead to a significant change in ABHD11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD11 and examine the expression of ABHD11. Does perturbing ABHD11 lead to a significant change in ABHD11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":331
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, VPS41 is perturbed and the expression of VPS41 is measured. Does this perturbation cause a significant change in VPS41 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, VPS41 is perturbed and the expression of VPS41 is measured. Does this perturbation cause a significant change in VPS41 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59200
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS19 is associated with a significant change in PCLAF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS19 is associated with a significant change in PCLAF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45225
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POLR2L and monitor FGD4 expression. Decide whether this perturbation leads to a significant alteration in FGD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POLR2L and monitor FGD4 expression. Decide whether this perturbation leads to a significant alteration in FGD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36918
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TWNK and monitor MT-ND6 expression. Decide whether this perturbation leads to a significant alteration in MT-ND6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TWNK and monitor MT-ND6 expression. Decide whether this perturbation leads to a significant alteration in MT-ND6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56738
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS24 is perturbed and MT-ND2 expression is measured. Determine whether MT-ND2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS24 is perturbed and MT-ND2 expression is measured. Determine whether MT-ND2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28529
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DONSON is perturbed and UCP2 expression is measured. Determine whether UCP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DONSON is perturbed and UCP2 expression is measured. Determine whether UCP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12919
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PARN and monitor RPL22L1 expression. Decide whether this perturbation leads to a significant alteration in RPL22L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PARN and monitor RPL22L1 expression. Decide whether this perturbation leads to a significant alteration in RPL22L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34188
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EEF1B2 and then measure expression of EEF1B2. Does this perturbation cause a significant change in EEF1B2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EEF1B2 and then measure expression of EEF1B2. Does this perturbation cause a significant change in EEF1B2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13744
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FNTA, does the expression profile of NMU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FNTA, does the expression profile of NMU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17057
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RFC1 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RFC1 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42164
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRIM2 and monitor GEMIN4 expression. Decide whether this perturbation leads to a significant alteration in GEMIN4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRIM2 and monitor GEMIN4 expression. Decide whether this perturbation leads to a significant alteration in GEMIN4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38488
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HUS1 is perturbed and the expression of KIF3B is measured. Determine whether KIF3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HUS1 is perturbed and the expression of KIF3B is measured. Determine whether KIF3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21046
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLRMT is perturbed and MT-ND6 expression is observed. Does this perturbation lead to a significant difference in MT-ND6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLRMT is perturbed and MT-ND6 expression is observed. Does this perturbation lead to a significant difference in MT-ND6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37213
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NFS1 and examine the expression of PIMREG. Does perturbing NFS1 lead to a significant change in PIMREG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NFS1 and examine the expression of PIMREG. Does perturbing NFS1 lead to a significant change in PIMREG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31321
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CYC1 is perturbed and CYC1 expression is quantified. Does this perturbation result in a significant change in CYC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CYC1 is perturbed and CYC1 expression is quantified. Does this perturbation result in a significant change in CYC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10482
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTC1 and monitor MT-ND6 expression. Decide whether this perturbation leads to a significant alteration in MT-ND6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTC1 and monitor MT-ND6 expression. Decide whether this perturbation leads to a significant alteration in MT-ND6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56148
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UPF1 is perturbed and the expression of EPB41L4A-AS1 is measured. Determine whether EPB41L4A-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UPF1 is perturbed and the expression of EPB41L4A-AS1 is measured. Determine whether EPB41L4A-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57806
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of DCPS. Does this perturbation cause a significant change in DCPS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of DCPS. Does this perturbation cause a significant change in DCPS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47414
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CD2BP2 and monitor TRIOBP expression. Decide whether this perturbation leads to a significant alteration in TRIOBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CD2BP2 and monitor TRIOBP expression. Decide whether this perturbation leads to a significant alteration in TRIOBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5928
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL18 and examine the expression of CDKN1A. Does perturbing RPL18 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL18 and examine the expression of CDKN1A. Does perturbing RPL18 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43571
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSTC is perturbed and XRCC2 expression is quantified. Does this perturbation result in a significant change in XRCC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSTC is perturbed and XRCC2 expression is quantified. Does this perturbation result in a significant change in XRCC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33882
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCAF1 is associated with a significant change in NR2F2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCAF1 is associated with a significant change in NR2F2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46935
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of PUS7 is measured. Does this perturbation cause a significant change in PUS7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of PUS7 is measured. Does this perturbation cause a significant change in PUS7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40420
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRXL2A and then measure expression of RAB38. Does this perturbation cause a significant change in RAB38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRXL2A and then measure expression of RAB38. Does this perturbation cause a significant change in RAB38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39054
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUB1 and then measure expression of MIOS. Does this perturbation cause a significant change in MIOS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUB1 and then measure expression of MIOS. Does this perturbation cause a significant change in MIOS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4184
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TXNL4A is perturbed and TXNL4A expression is quantified. Does this perturbation result in a significant change in TXNL4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TXNL4A is perturbed and TXNL4A expression is quantified. Does this perturbation result in a significant change in TXNL4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56842
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPS4 is perturbed and the expression of CLSPN is measured. Determine whether CLSPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPS4 is perturbed and the expression of CLSPN is measured. Determine whether CLSPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8936
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCDC59 is perturbed and the expression of FANCD2 is measured. Determine whether FANCD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCDC59 is perturbed and the expression of FANCD2 is measured. Determine whether FANCD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5306
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RNF8 and examine the expression of DCTPP1. Does perturbing RNF8 lead to a significant change in DCTPP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RNF8 and examine the expression of DCTPP1. Does perturbing RNF8 lead to a significant change in DCTPP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42831
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG2 is perturbed and SEC61B expression is quantified. Does this perturbation result in a significant change in SEC61B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG2 is perturbed and SEC61B expression is quantified. Does this perturbation result in a significant change in SEC61B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1202
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD13, does the expression profile of GABARAPL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD13, does the expression profile of GABARAPL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39767
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PAF1, does the expression profile of CDKN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PAF1, does the expression profile of CDKN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34027
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ANAPC4 is perturbed and the expression of PSMC3IP is measured. Determine whether PSMC3IP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ANAPC4 is perturbed and the expression of PSMC3IP is measured. Determine whether PSMC3IP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1436
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSNK2B is perturbed and CSNK2B expression is observed. Does this perturbation lead to a significant difference in CSNK2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSNK2B is perturbed and CSNK2B expression is observed. Does this perturbation lead to a significant difference in CSNK2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9933
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF6 is perturbed and DTNBP1 expression is quantified. Does this perturbation result in a significant change in DTNBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF6 is perturbed and DTNBP1 expression is quantified. Does this perturbation result in a significant change in DTNBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38952
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INPPL1 is perturbed and DCTN5 expression is quantified. Does this perturbation result in a significant change in DCTN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INPPL1 is perturbed and DCTN5 expression is quantified. Does this perturbation result in a significant change in DCTN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21702
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR61 is perturbed and FBXO32 expression is quantified. Does this perturbation result in a significant change in FBXO32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR61 is perturbed and FBXO32 expression is quantified. Does this perturbation result in a significant change in FBXO32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59982
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUB1, does the expression profile of OLA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUB1, does the expression profile of OLA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32707
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP19 is perturbed and the expression of CYB5R4 is measured. Determine whether CYB5R4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP19 is perturbed and the expression of CYB5R4 is measured. Determine whether CYB5R4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51116
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAMLG, does the expression profile of CAMLG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAMLG, does the expression profile of CAMLG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4867
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PCID2 is perturbed and PCID2 expression is measured. Determine whether PCID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PCID2 is perturbed and PCID2 expression is measured. Determine whether PCID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34339
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MVD, does the expression profile of MT-ND3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MVD, does the expression profile of MT-ND3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29247
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSNK2B is perturbed and the expression of SELENOM is measured. Does this perturbation cause a significant change in SELENOM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSNK2B is perturbed and the expression of SELENOM is measured. Does this perturbation cause a significant change in SELENOM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9950
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOC2, does the expression profile of CDCA8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOC2, does the expression profile of CDCA8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15797
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4A3 is associated with a significant change in TARBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4A3 is associated with a significant change in TARBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14665
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS18 is perturbed and the expression of CEP128 is measured. Determine whether CEP128 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS18 is perturbed and the expression of CEP128 is measured. Determine whether CEP128 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45186
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RRM1 is perturbed and RRM1 expression is measured. Determine whether RRM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RRM1 is perturbed and RRM1 expression is measured. Determine whether RRM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45939
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of DR1 is measured. Determine whether DR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of DR1 is measured. Determine whether DR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13136
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5F1A and examine the expression of MT-CO3. Does perturbing ATP5F1A lead to a significant change in MT-CO3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5F1A and examine the expression of MT-CO3. Does perturbing ATP5F1A lead to a significant change in MT-CO3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2471
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCT8 and then measure expression of E2F1. Does this perturbation cause a significant change in E2F1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCT8 and then measure expression of E2F1. Does this perturbation cause a significant change in E2F1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5884
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAP30BP is perturbed and COL13A1 expression is measured. Determine whether COL13A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAP30BP is perturbed and COL13A1 expression is measured. Determine whether COL13A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46659
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSBP is perturbed and MCM5 expression is measured. Determine whether MCM5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSBP is perturbed and MCM5 expression is measured. Determine whether MCM5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33829
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NFS1 and then measure expression of TMEM97. Does this perturbation cause a significant change in TMEM97 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NFS1 and then measure expression of TMEM97. Does this perturbation cause a significant change in TMEM97 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31334
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR1D, does the expression profile of NMU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR1D, does the expression profile of NMU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36557
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FASTKD5 is perturbed and MT-ATP6 expression is observed. Does this perturbation lead to a significant difference in MT-ATP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FASTKD5 is perturbed and MT-ATP6 expression is observed. Does this perturbation lead to a significant difference in MT-ATP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16563
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK6 is associated with a significant change in MCCC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK6 is associated with a significant change in MCCC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6555
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBA52 is perturbed and the expression of PCLAF is measured. Does this perturbation cause a significant change in PCLAF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBA52 is perturbed and the expression of PCLAF is measured. Does this perturbation cause a significant change in PCLAF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57110
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A9 is perturbed and ERH expression is measured. Determine whether ERH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A9 is perturbed and ERH expression is measured. Determine whether ERH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48849
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1C1 is perturbed and HMGCS1 expression is measured. Determine whether HMGCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1C1 is perturbed and HMGCS1 expression is measured. Determine whether HMGCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2929
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAB1 is perturbed and the expression of NDUFAB1 is measured. Does this perturbation cause a significant change in NDUFAB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAB1 is perturbed and the expression of NDUFAB1 is measured. Does this perturbation cause a significant change in NDUFAB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30600
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2H2 is associated with a significant change in FANCG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2H2 is associated with a significant change in FANCG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19015
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RBM48 is perturbed and FANCD2 expression is measured. Determine whether FANCD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RBM48 is perturbed and FANCD2 expression is measured. Determine whether FANCD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41819
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR44 is perturbed and EMP3 expression is quantified. Does this perturbation result in a significant change in EMP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR44 is perturbed and EMP3 expression is quantified. Does this perturbation result in a significant change in EMP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59832
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GABPB1 is perturbed and GABPB1 expression is measured. Determine whether GABPB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GABPB1 is perturbed and GABPB1 expression is measured. Determine whether GABPB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17229
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR25 and then measure expression of POLE. Does this perturbation cause a significant change in POLE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR25 and then measure expression of POLE. Does this perturbation cause a significant change in POLE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59614
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARL2 is perturbed and the expression of ARHGAP22 is measured. Does this perturbation cause a significant change in ARHGAP22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARL2 is perturbed and the expression of ARHGAP22 is measured. Does this perturbation cause a significant change in ARHGAP22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1930
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOL8 is perturbed and the expression of LMNB1 is measured. Does this perturbation cause a significant change in LMNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOL8 is perturbed and the expression of LMNB1 is measured. Does this perturbation cause a significant change in LMNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31980
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS17 is perturbed and SPAG5 expression is measured. Determine whether SPAG5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS17 is perturbed and SPAG5 expression is measured. Determine whether SPAG5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45159
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSG101 is perturbed and the expression of STIL is measured. Determine whether STIL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSG101 is perturbed and the expression of STIL is measured. Determine whether STIL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56056
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR55 is associated with a significant change in ZWINT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR55 is associated with a significant change in ZWINT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59945
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF3C4 is perturbed and the expression of NME2 is measured. Determine whether NME2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF3C4 is perturbed and the expression of NME2 is measured. Determine whether NME2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19216
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AURKA and then measure expression of ERCC6L. Does this perturbation cause a significant change in ERCC6L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AURKA and then measure expression of ERCC6L. Does this perturbation cause a significant change in ERCC6L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3174
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DONSON is perturbed and the expression of GINS1 is measured. Determine whether GINS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DONSON is perturbed and the expression of GINS1 is measured. Determine whether GINS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12926
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb VCP and examine the expression of PIMREG. Does perturbing VCP lead to a significant change in PIMREG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb VCP and examine the expression of PIMREG. Does perturbing VCP lead to a significant change in PIMREG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58831
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GUCD1 is perturbed and the expression of WDR35 is measured. Determine whether WDR35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GUCD1 is perturbed and the expression of WDR35 is measured. Determine whether WDR35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19336
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LIMS1 is perturbed and the expression of PLAT is measured. Does this perturbation cause a significant change in PLAT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LIMS1 is perturbed and the expression of PLAT is measured. Does this perturbation cause a significant change in PLAT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23890
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFS3 is perturbed and the expression of IGFBP5 is measured. Does this perturbation cause a significant change in IGFBP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFS3 is perturbed and the expression of IGFBP5 is measured. Does this perturbation cause a significant change in IGFBP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30920
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TFAM is perturbed and MTRNR2L12 expression is measured. Determine whether MTRNR2L12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TFAM is perturbed and MTRNR2L12 expression is measured. Determine whether MTRNR2L12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53569
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TUBE1 is perturbed and ZMAT3 expression is measured. Determine whether ZMAT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TUBE1 is perturbed and ZMAT3 expression is measured. Determine whether ZMAT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56489
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DPY19L4 is perturbed and DBNDD2 expression is measured. Determine whether DBNDD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DPY19L4 is perturbed and DBNDD2 expression is measured. Determine whether DBNDD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13109
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB10 and examine the expression of S100A11. Does perturbing TMSB10 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB10 and examine the expression of S100A11. Does perturbing TMSB10 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54791
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF6 is perturbed and the expression of TAF6 is measured. Determine whether TAF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF6 is perturbed and the expression of TAF6 is measured. Determine whether TAF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52806
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SASS6 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SASS6 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46855
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF1AD and monitor MND1 expression. Decide whether this perturbation leads to a significant alteration in MND1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF1AD and monitor MND1 expression. Decide whether this perturbation leads to a significant alteration in MND1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14038
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OPA1 is associated with a significant change in OPA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OPA1 is associated with a significant change in OPA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33635
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TWSG1 and then measure expression of HAUS1. Does this perturbation cause a significant change in HAUS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TWSG1 and then measure expression of HAUS1. Does this perturbation cause a significant change in HAUS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56774
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GEMIN5 and examine the expression of GEMIN5. Does perturbing GEMIN5 lead to a significant change in GEMIN5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GEMIN5 and examine the expression of GEMIN5. Does perturbing GEMIN5 lead to a significant change in GEMIN5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17491
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4A3 is perturbed and EPB41 expression is measured. Determine whether EPB41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4A3 is perturbed and EPB41 expression is measured. Determine whether EPB41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14659
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL31 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL31 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44015
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TUBB2A and then measure expression of RRAS. Does this perturbation cause a significant change in RRAS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TUBB2A and then measure expression of RRAS. Does this perturbation cause a significant change in RRAS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56454
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC37 is associated with a significant change in RAC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC37 is associated with a significant change in RAC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6165
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD10 is perturbed and KCTD10 expression is measured. Determine whether KCTD10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD10 is perturbed and KCTD10 expression is measured. Determine whether KCTD10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22819
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RCL1, does the expression profile of SPAG5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RCL1, does the expression profile of SPAG5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42057
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRRAP and examine the expression of ADM. Does perturbing TRRAP lead to a significant change in ADM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRRAP and examine the expression of ADM. Does perturbing TRRAP lead to a significant change in ADM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55901
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOSC7 is perturbed and the expression of FANCA is measured. Determine whether FANCA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOSC7 is perturbed and the expression of FANCA is measured. Determine whether FANCA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16166
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMA4 is associated with a significant change in GABARAPL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMA4 is associated with a significant change in GABARAPL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39195
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and SLC3A2 expression is quantified. Does this perturbation result in a significant change in SLC3A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and SLC3A2 expression is quantified. Does this perturbation result in a significant change in SLC3A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50722
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPS16 and monitor MRPS16 expression. Decide whether this perturbation leads to a significant alteration in MRPS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPS16 and monitor MRPS16 expression. Decide whether this perturbation leads to a significant alteration in MRPS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28238
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBM48 is perturbed and the expression of FANCD2 is measured. Does this perturbation cause a significant change in FANCD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBM48 is perturbed and the expression of FANCD2 is measured. Does this perturbation cause a significant change in FANCD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41810
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCS1L is perturbed and PIGC expression is quantified. Does this perturbation result in a significant change in PIGC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCS1L is perturbed and PIGC expression is quantified. Does this perturbation result in a significant change in PIGC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3532
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOC5 is perturbed and the expression of CLIC1 is measured. Determine whether CLIC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOC5 is perturbed and the expression of CLIC1 is measured. Determine whether CLIC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15876
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EEF1G, does the expression profile of NUPR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EEF1G, does the expression profile of NUPR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13787
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KDM2A and examine the expression of SSR2. Does perturbing KDM2A lead to a significant change in SSR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KDM2A and examine the expression of SSR2. Does perturbing KDM2A lead to a significant change in SSR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22861
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB4 is associated with a significant change in C6orf136 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB4 is associated with a significant change in C6orf136 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61035
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS22 is associated with a significant change in MTRNR2L12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS22 is associated with a significant change in MTRNR2L12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28465
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BNIP1 and monitor TYMS expression. Decide whether this perturbation leads to a significant alteration in TYMS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BNIP1 and monitor TYMS expression. Decide whether this perturbation leads to a significant alteration in TYMS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3718
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EMC3 is perturbed and the expression of LXN is measured. Determine whether LXN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EMC3 is perturbed and the expression of LXN is measured. Determine whether LXN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15256
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDIPT and examine the expression of CAV2. Does perturbing CDIPT lead to a significant change in CAV2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDIPT and examine the expression of CAV2. Does perturbing CDIPT lead to a significant change in CAV2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6411
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CENPW is perturbed and the expression of XRN2 is measured. Determine whether XRN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CENPW is perturbed and the expression of XRN2 is measured. Determine whether XRN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6986
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DICER1 is perturbed and CDK6 expression is measured. Determine whether CDK6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DICER1 is perturbed and CDK6 expression is measured. Determine whether CDK6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12319
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSP90B1 is associated with a significant change in PDIA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSP90B1 is associated with a significant change in PDIA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20785
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF236 is perturbed and the expression of HSP90AB1 is measured. Determine whether HSP90AB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF236 is perturbed and the expression of HSP90AB1 is measured. Determine whether HSP90AB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61526
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TOX4 is perturbed and the expression of MYH10 is measured. Does this perturbation cause a significant change in MYH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TOX4 is perturbed and the expression of MYH10 is measured. Does this perturbation cause a significant change in MYH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55180
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEM1 is perturbed and the expression of SEM1 is measured. Does this perturbation cause a significant change in SEM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEM1 is perturbed and the expression of SEM1 is measured. Does this perturbation cause a significant change in SEM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47520
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EEFSEC is perturbed and TRMT5 expression is measured. Determine whether TRMT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EEFSEC is perturbed and TRMT5 expression is measured. Determine whether TRMT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13849
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and MT-ND2 expression is quantified. Does this perturbation result in a significant change in MT-ND2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and MT-ND2 expression is quantified. Does this perturbation result in a significant change in MT-ND2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27712
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AATF and then measure expression of PIMREG. Does this perturbation cause a significant change in PIMREG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AATF and then measure expression of PIMREG. Does this perturbation cause a significant change in PIMREG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":204
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BMS1 is perturbed and BMS1 expression is measured. Determine whether BMS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BMS1 is perturbed and BMS1 expression is measured. Determine whether BMS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3689
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1F is perturbed and ATP6V1F expression is observed. Does this perturbation lead to a significant difference in ATP6V1F expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1F is perturbed and ATP6V1F expression is observed. Does this perturbation lead to a significant difference in ATP6V1F expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3003
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NFRKB is perturbed and NUDT2 expression is quantified. Does this perturbation result in a significant change in NUDT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NFRKB is perturbed and NUDT2 expression is quantified. Does this perturbation result in a significant change in NUDT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31302
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MSTO1 and then measure expression of VHL. Does this perturbation cause a significant change in VHL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MSTO1 and then measure expression of VHL. Does this perturbation cause a significant change in VHL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29024
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PNO1 is perturbed and TACC3 expression is observed. Does this perturbation lead to a significant difference in TACC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PNO1 is perturbed and TACC3 expression is observed. Does this perturbation lead to a significant difference in TACC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36073
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C5orf30 is associated with a significant change in SMOX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C5orf30 is associated with a significant change in SMOX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4615
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOL9 is associated with a significant change in CCNB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOL9 is associated with a significant change in CCNB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32025
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBMX2, does the expression profile of SYNE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBMX2, does the expression profile of SYNE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41907
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRSF11 is perturbed and the expression of EMP3 is measured. Does this perturbation cause a significant change in EMP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRSF11 is perturbed and the expression of EMP3 is measured. Does this perturbation cause a significant change in EMP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51430
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TRAPPC3 is associated with a significant change in SERPINB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TRAPPC3 is associated with a significant change in SERPINB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55545
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GFOD2 is perturbed and PLAT expression is quantified. Does this perturbation result in a significant change in PLAT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GFOD2 is perturbed and PLAT expression is quantified. Does this perturbation result in a significant change in PLAT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17752
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC25A26 is perturbed and the expression of EPDR1 is measured. Determine whether EPDR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC25A26 is perturbed and the expression of EPDR1 is measured. Determine whether EPDR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48626
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP85 is perturbed and TMPO expression is observed. Does this perturbation lead to a significant difference in TMPO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP85 is perturbed and TMPO expression is observed. Does this perturbation lead to a significant difference in TMPO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33353
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRKRIP1 is perturbed and MCM2 expression is measured. Determine whether MCM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRKRIP1 is perturbed and MCM2 expression is measured. Determine whether MCM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38579
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FAU is perturbed and FAU expression is quantified. Does this perturbation result in a significant change in FAU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FAU is perturbed and FAU expression is quantified. Does this perturbation result in a significant change in FAU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16592
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR2E is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR2E is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36740
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PEX19 is perturbed and DYNLRB1 expression is observed. Does this perturbation lead to a significant difference in DYNLRB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PEX19 is perturbed and DYNLRB1 expression is observed. Does this perturbation lead to a significant difference in DYNLRB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34923
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS24 is perturbed and CDCA5 expression is measured. Determine whether CDCA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS24 is perturbed and CDCA5 expression is measured. Determine whether CDCA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45419
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UNC50 is associated with a significant change in CETN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UNC50 is associated with a significant change in CETN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57765
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35G2 and examine the expression of STMP1. Does perturbing SLC35G2 lead to a significant change in STMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35G2 and examine the expression of STMP1. Does perturbing SLC35G2 lead to a significant change in STMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48761
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLD3 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLD3 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36316
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R15B is perturbed and the expression of HDGFL2 is measured. Determine whether HDGFL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R15B is perturbed and the expression of HDGFL2 is measured. Determine whether HDGFL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37846
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PELP1 is associated with a significant change in BIRC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PELP1 is associated with a significant change in BIRC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34815
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CRLS1 and monitor C7orf26 expression. Decide whether this perturbation leads to a significant alteration in C7orf26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CRLS1 and monitor C7orf26 expression. Decide whether this perturbation leads to a significant alteration in C7orf26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9778
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TFRC is perturbed and TFRC expression is quantified. Does this perturbation result in a significant change in TFRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TFRC is perturbed and TFRC expression is quantified. Does this perturbation result in a significant change in TFRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53702
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GET3 is perturbed and the expression of KDELR3 is measured. Does this perturbation cause a significant change in KDELR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GET3 is perturbed and the expression of KDELR3 is measured. Does this perturbation cause a significant change in KDELR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17660
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM5 is perturbed and the expression of STMN1 is measured. Does this perturbation cause a significant change in STMN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM5 is perturbed and the expression of STMN1 is measured. Does this perturbation cause a significant change in STMN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24280
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AP2A1 is perturbed and the expression of TPX2 is measured. Determine whether TPX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AP2A1 is perturbed and the expression of TPX2 is measured. Determine whether TPX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1626
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of MRPL39. Does this perturbation cause a significant change in MRPL39 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of MRPL39. Does this perturbation cause a significant change in MRPL39 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27694
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ANAPC13 is perturbed and CEP63 expression is observed. Does this perturbation lead to a significant difference in CEP63 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ANAPC13 is perturbed and CEP63 expression is observed. Does this perturbation lead to a significant difference in CEP63 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1373
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DYNC1I2 is perturbed and DYNC1I2 expression is observed. Does this perturbation lead to a significant difference in DYNC1I2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DYNC1I2 is perturbed and DYNC1I2 expression is observed. Does this perturbation lead to a significant difference in DYNC1I2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13413
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NR2C2AP and examine the expression of MCM2. Does perturbing NR2C2AP lead to a significant change in MCM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NR2C2AP and examine the expression of MCM2. Does perturbing NR2C2AP lead to a significant change in MCM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32411
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NDUFS5 and monitor TBL1X expression. Decide whether this perturbation leads to a significant alteration in TBL1X expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NDUFS5 and monitor TBL1X expression. Decide whether this perturbation leads to a significant alteration in TBL1X expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30948
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLRX3 is perturbed and GLRX3 expression is observed. Does this perturbation lead to a significant difference in GLRX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLRX3 is perturbed and GLRX3 expression is observed. Does this perturbation lead to a significant difference in GLRX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18033
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZWINT is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZWINT is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62063
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC25A10 and monitor MRPL12 expression. Decide whether this perturbation leads to a significant alteration in MRPL12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC25A10 and monitor MRPL12 expression. Decide whether this perturbation leads to a significant alteration in MRPL12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48578
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELP5, does the expression profile of PSAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELP5, does the expression profile of PSAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15157
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UQCRB and examine the expression of UQCRB. Does perturbing UQCRB lead to a significant change in UQCRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UQCRB and examine the expression of UQCRB. Does perturbing UQCRB lead to a significant change in UQCRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57871
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMC6 is perturbed and PTN expression is quantified. Does this perturbation result in a significant change in PTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMC6 is perturbed and PTN expression is quantified. Does this perturbation result in a significant change in PTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39632
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDCD6IP, does the expression profile of LATS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDCD6IP, does the expression profile of LATS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34617
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSTF3 is perturbed and PHF11 expression is measured. Determine whether PHF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSTF3 is perturbed and PHF11 expression is measured. Determine whether PHF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10019
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which VPS28 is perturbed and CXCL8 expression is observed. Does this perturbation lead to a significant difference in CXCL8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which VPS28 is perturbed and CXCL8 expression is observed. Does this perturbation lead to a significant difference in CXCL8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59053
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS25 and examine the expression of TNIK. Does perturbing MRPS25 lead to a significant change in TNIK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS25 and examine the expression of TNIK. Does perturbing MRPS25 lead to a significant change in TNIK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28541
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YBX3 is perturbed and YBX3 expression is observed. Does this perturbation lead to a significant difference in YBX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YBX3 is perturbed and YBX3 expression is observed. Does this perturbation lead to a significant difference in YBX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60723
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GYG1 is perturbed and GYG1 expression is observed. Does this perturbation lead to a significant difference in GYG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GYG1 is perturbed and GYG1 expression is observed. Does this perturbation lead to a significant difference in GYG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19383
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRRT is perturbed and the expression of UQCC2 is measured. Does this perturbation cause a significant change in UQCC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRRT is perturbed and the expression of UQCC2 is measured. Does this perturbation cause a significant change in UQCC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51350
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PELO is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PELO is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34780
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELP4 is perturbed and IL11 expression is observed. Does this perturbation lead to a significant difference in IL11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELP4 is perturbed and IL11 expression is observed. Does this perturbation lead to a significant difference in IL11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15133
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAC3, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAC3, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40977
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFB4 is perturbed and WDR45 expression is observed. Does this perturbation lead to a significant difference in WDR45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFB4 is perturbed and WDR45 expression is observed. Does this perturbation lead to a significant difference in WDR45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30803
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSME2, does the expression profile of TJAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSME2, does the expression profile of TJAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40067
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS8 is perturbed and the expression of H1FX is measured. Does this perturbation cause a significant change in H1FX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS8 is perturbed and the expression of H1FX is measured. Does this perturbation cause a significant change in H1FX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9020
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CYREN and then measure expression of CYREN. Does this perturbation cause a significant change in CYREN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CYREN and then measure expression of CYREN. Does this perturbation cause a significant change in CYREN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10564
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RCOR1 and then measure expression of SPP1. Does this perturbation cause a significant change in SPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RCOR1 and then measure expression of SPP1. Does this perturbation cause a significant change in SPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42084
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MMGT1 and monitor MMGT1 expression. Decide whether this perturbation leads to a significant alteration in MMGT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MMGT1 and monitor MMGT1 expression. Decide whether this perturbation leads to a significant alteration in MMGT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26588
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb WDR33 and monitor POLQ expression. Decide whether this perturbation leads to a significant alteration in POLQ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb WDR33 and monitor POLQ expression. Decide whether this perturbation leads to a significant alteration in POLQ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59728
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD11 is associated with a significant change in MT1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD11 is associated with a significant change in MT1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1525
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIS18BP1 is perturbed and MCM2 expression is quantified. Does this perturbation result in a significant change in MCM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIS18BP1 is perturbed and MCM2 expression is quantified. Does this perturbation result in a significant change in MCM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26462
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDC23 is perturbed and GTF3C6 expression is quantified. Does this perturbation result in a significant change in GTF3C6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDC23 is perturbed and GTF3C6 expression is quantified. Does this perturbation result in a significant change in GTF3C6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6082
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAB6A, does the expression profile of RAB6A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAB6A, does the expression profile of RAB6A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40857
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PCNA is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PCNA is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34399
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C12orf45 and then measure expression of NCAPG2. Does this perturbation cause a significant change in NCAPG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C12orf45 and then measure expression of NCAPG2. Does this perturbation cause a significant change in NCAPG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4374
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD3 is perturbed and CTSH expression is quantified. Does this perturbation result in a significant change in CTSH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD3 is perturbed and CTSH expression is quantified. Does this perturbation result in a significant change in CTSH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45882
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MOK and monitor MSL3 expression. Decide whether this perturbation leads to a significant alteration in MSL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MOK and monitor MSL3 expression. Decide whether this perturbation leads to a significant alteration in MSL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26738
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOB1 is associated with a significant change in NOB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOB1 is associated with a significant change in NOB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31715
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNRPD3 is perturbed and KIFC1 expression is quantified. Does this perturbation result in a significant change in KIFC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNRPD3 is perturbed and KIFC1 expression is quantified. Does this perturbation result in a significant change in KIFC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50132
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR26 and then measure expression of BDH1. Does this perturbation cause a significant change in BDH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR26 and then measure expression of BDH1. Does this perturbation cause a significant change in BDH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59664
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STRIP1 is perturbed and HGSNAT expression is observed. Does this perturbation lead to a significant difference in HGSNAT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STRIP1 is perturbed and HGSNAT expression is observed. Does this perturbation lead to a significant difference in HGSNAT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51863
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBR5 is perturbed and the expression of HLA-A is measured. Determine whether HLA-A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBR5 is perturbed and the expression of HLA-A is measured. Determine whether HLA-A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57536
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDCD6 and examine the expression of UCHL1. Does perturbing PDCD6 lead to a significant change in UCHL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDCD6 and examine the expression of UCHL1. Does perturbing PDCD6 lead to a significant change in UCHL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34581
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDK12 is perturbed and CDK12 expression is quantified. Does this perturbation result in a significant change in CDK12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDK12 is perturbed and CDK12 expression is quantified. Does this perturbation result in a significant change in CDK12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6482
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPF1 is perturbed and CIT expression is quantified. Does this perturbation result in a significant change in CIT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPF1 is perturbed and CIT expression is quantified. Does this perturbation result in a significant change in CIT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43242
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SETD5, does the expression profile of SETD5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SETD5, does the expression profile of SETD5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47767
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XPO5 is perturbed and the expression of XPO5 is measured. Determine whether XPO5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XPO5 is perturbed and the expression of XPO5 is measured. Determine whether XPO5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60406
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPP38, does the expression profile of NSMCE4A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPP38, does the expression profile of NSMCE4A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44867
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USP9X and then measure expression of USP9X. Does this perturbation cause a significant change in USP9X expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USP9X and then measure expression of USP9X. Does this perturbation cause a significant change in USP9X expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58414
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUD31 is perturbed and BUD31 expression is quantified. Does this perturbation result in a significant change in BUD31 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUD31 is perturbed and BUD31 expression is quantified. Does this perturbation result in a significant change in BUD31 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4312
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5MD is perturbed and the expression of MYBL2 is measured. Does this perturbation cause a significant change in MYBL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5MD is perturbed and the expression of MYBL2 is measured. Does this perturbation cause a significant change in MYBL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2550
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF407 is associated with a significant change in CLCN7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF407 is associated with a significant change in CLCN7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61615
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPSF4 is perturbed and the expression of HIST1H1B is measured. Determine whether HIST1H1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPSF4 is perturbed and the expression of HIST1H1B is measured. Determine whether HIST1H1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9636
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SBDS and examine the expression of PTPRJ. Does perturbing SBDS lead to a significant change in PTPRJ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SBDS and examine the expression of PTPRJ. Does perturbing SBDS lead to a significant change in PTPRJ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46881
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRBD1 is perturbed and the expression of HIST1H2AH is measured. Determine whether HIST1H2AH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRBD1 is perturbed and the expression of HIST1H2AH is measured. Determine whether HIST1H2AH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50946
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DBR1 is perturbed and VCAN expression is measured. Determine whether VCAN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DBR1 is perturbed and VCAN expression is measured. Determine whether VCAN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10759
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SF3B3, does the expression profile of DNMT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SF3B3, does the expression profile of DNMT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48057
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNMT is associated with a significant change in SNHG8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNMT is associated with a significant change in SNHG8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42885
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARL6IP6 is perturbed and the expression of CDC6 is measured. Determine whether CDC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARL6IP6 is perturbed and the expression of CDC6 is measured. Determine whether CDC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2006
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RBM10 and monitor NDUFB11 expression. Decide whether this perturbation leads to a significant alteration in NDUFB11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RBM10 and monitor NDUFB11 expression. Decide whether this perturbation leads to a significant alteration in NDUFB11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41498
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS18 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS18 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45196
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BRD8 is perturbed and CEP135 expression is quantified. Does this perturbation result in a significant change in CEP135 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BRD8 is perturbed and CEP135 expression is quantified. Does this perturbation result in a significant change in CEP135 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3942
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INF2 and examine the expression of BLOC1S1. Does perturbing INF2 lead to a significant change in BLOC1S1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INF2 and examine the expression of BLOC1S1. Does perturbing INF2 lead to a significant change in BLOC1S1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21491
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPATA5L1 is perturbed and the expression of INCENP is measured. Does this perturbation cause a significant change in INCENP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPATA5L1 is perturbed and the expression of INCENP is measured. Does this perturbation cause a significant change in INCENP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50580
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCNQ is perturbed and CCNE2 expression is quantified. Does this perturbation result in a significant change in CCNE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCNQ is perturbed and CCNE2 expression is quantified. Does this perturbation result in a significant change in CCNE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5662
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRP12 is perturbed and the expression of ESCO2 is measured. Determine whether ESCO2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRP12 is perturbed and the expression of ESCO2 is measured. Determine whether ESCO2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46076
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LAMTOR2 is perturbed and the expression of LAMTOR2 is measured. Determine whether LAMTOR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LAMTOR2 is perturbed and the expression of LAMTOR2 is measured. Determine whether LAMTOR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23596
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDAP1 is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDAP1 is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34456
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb H2AFZ and examine the expression of H2AFZ. Does perturbing H2AFZ lead to a significant change in H2AFZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb H2AFZ and examine the expression of H2AFZ. Does perturbing H2AFZ lead to a significant change in H2AFZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19441
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBE1 and examine the expression of FAM229B. Does perturbing TUBE1 lead to a significant change in FAM229B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBE1 and examine the expression of FAM229B. Does perturbing TUBE1 lead to a significant change in FAM229B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56461
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELP3 is perturbed and NUPR1 expression is quantified. Does this perturbation result in a significant change in NUPR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELP3 is perturbed and NUPR1 expression is quantified. Does this perturbation result in a significant change in NUPR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15092
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCAPG2 and examine the expression of NUDT6. Does perturbing NCAPG2 lead to a significant change in NUDT6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCAPG2 and examine the expression of NUDT6. Does perturbing NCAPG2 lead to a significant change in NUDT6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30141
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRXL2A is perturbed and PRXL2A expression is quantified. Does this perturbation result in a significant change in PRXL2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRXL2A is perturbed and PRXL2A expression is quantified. Does this perturbation result in a significant change in PRXL2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39032
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BRIP1 is perturbed and the expression of UBE2H is measured. Determine whether UBE2H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BRIP1 is perturbed and the expression of UBE2H is measured. Determine whether UBE2H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4016
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RANGAP1 is associated with a significant change in CNIH4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RANGAP1 is associated with a significant change in CNIH4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41295
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLG is perturbed and the expression of ADORA2B is measured. Determine whether ADORA2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLG is perturbed and the expression of ADORA2B is measured. Determine whether ADORA2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36406
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DCTN4 and then measure expression of NASP. Does this perturbation cause a significant change in NASP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DCTN4 and then measure expression of NASP. Does this perturbation cause a significant change in NASP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10904
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNRNPH1 is perturbed and HNRNPH1 expression is quantified. Does this perturbation result in a significant change in HNRNPH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNRNPH1 is perturbed and HNRNPH1 expression is quantified. Does this perturbation result in a significant change in HNRNPH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20442
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SART1 and then measure expression of CENPW. Does this perturbation cause a significant change in CENPW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SART1 and then measure expression of CENPW. Does this perturbation cause a significant change in CENPW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46774
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYMPK is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYMPK is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52365
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LETM1 and examine the expression of PSAT1. Does perturbing LETM1 lead to a significant change in PSAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LETM1 and examine the expression of PSAT1. Does perturbing LETM1 lead to a significant change in PSAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23861
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNX15, does the expression profile of ARL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNX15, does the expression profile of ARL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50347
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGS1 and examine the expression of CLSPN. Does perturbing TGS1 lead to a significant change in CLSPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGS1 and examine the expression of CLSPN. Does perturbing TGS1 lead to a significant change in CLSPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53751
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK11A is associated with a significant change in CDC42BPB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK11A is associated with a significant change in CDC42BPB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6465
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCUN1D5 is perturbed and the expression of PCLAF is measured. Determine whether PCLAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCUN1D5 is perturbed and the expression of PCLAF is measured. Determine whether PCLAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10996
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METTL21A is perturbed and SLC7A11 expression is quantified. Does this perturbation result in a significant change in SLC7A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METTL21A is perturbed and SLC7A11 expression is quantified. Does this perturbation result in a significant change in SLC7A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26142
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAXBP1 is associated with a significant change in GAS5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAXBP1 is associated with a significant change in GAS5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34225
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RSL24D1 and examine the expression of SLU7. Does perturbing RSL24D1 lead to a significant change in SLU7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RSL24D1 and examine the expression of SLU7. Does perturbing RSL24D1 lead to a significant change in SLU7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46251
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PKMYT1 is perturbed and PKMYT1 expression is observed. Does this perturbation lead to a significant difference in PKMYT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PKMYT1 is perturbed and PKMYT1 expression is observed. Does this perturbation lead to a significant difference in PKMYT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35743
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMC4 is perturbed and SMARCD3 expression is measured. Determine whether SMARCD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMC4 is perturbed and SMARCD3 expression is measured. Determine whether SMARCD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39589
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCT5 and then measure expression of FANCI. Does this perturbation cause a significant change in FANCI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCT5 and then measure expression of FANCI. Does this perturbation cause a significant change in FANCI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5804
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCDC59 is perturbed and SGO1 expression is observed. Does this perturbation lead to a significant difference in SGO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCDC59 is perturbed and SGO1 expression is observed. Does this perturbation lead to a significant difference in SGO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5283
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which METTL16 is perturbed and NAA16 expression is observed. Does this perturbation lead to a significant difference in NAA16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which METTL16 is perturbed and NAA16 expression is observed. Does this perturbation lead to a significant difference in NAA16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26083
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS3, does the expression profile of POLE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS3, does the expression profile of POLE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21957
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35G2 is perturbed and the expression of SLC35G2 is measured. Determine whether SLC35G2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35G2 is perturbed and the expression of SLC35G2 is measured. Determine whether SLC35G2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48756
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF574 and examine the expression of MYL9. Does perturbing ZNF574 lead to a significant change in MYL9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF574 and examine the expression of MYL9. Does perturbing ZNF574 lead to a significant change in MYL9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61641
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBCB and examine the expression of FIGNL1. Does perturbing TBCB lead to a significant change in FIGNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBCB and examine the expression of FIGNL1. Does perturbing TBCB lead to a significant change in FIGNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53121
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNRNPK is perturbed and the expression of ATP5F1D is measured. Does this perturbation cause a significant change in ATP5F1D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNRNPK is perturbed and the expression of ATP5F1D is measured. Does this perturbation cause a significant change in ATP5F1D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20470
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT2 and examine the expression of BUB1B. Does perturbing CCT2 lead to a significant change in BUB1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT2 and examine the expression of BUB1B. Does perturbing CCT2 lead to a significant change in BUB1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5721
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPL and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPL and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20498
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAP18 is perturbed and the expression of SLC25A46 is measured. Does this perturbation cause a significant change in SLC25A46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAP18 is perturbed and the expression of SLC25A46 is measured. Does this perturbation cause a significant change in SLC25A46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46640
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CTU2 is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CTU2 is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10206
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and SEC61B expression is measured. Determine whether SEC61B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and SEC61B expression is measured. Determine whether SEC61B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47379
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NAF1 is associated with a significant change in GPSM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NAF1 is associated with a significant change in GPSM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29775
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4A3 is perturbed and the expression of EPB41 is measured. Does this perturbation cause a significant change in EPB41 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4A3 is perturbed and the expression of EPB41 is measured. Does this perturbation cause a significant change in EPB41 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14650
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MDN1, does the expression profile of INPP5F indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MDN1, does the expression profile of INPP5F indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25367
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM8A and examine the expression of BRCA1. Does perturbing RBM8A lead to a significant change in BRCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM8A and examine the expression of BRCA1. Does perturbing RBM8A lead to a significant change in BRCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41831
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ANKRD39 is perturbed and CDC25C expression is measured. Determine whether CDC25C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ANKRD39 is perturbed and CDC25C expression is measured. Determine whether CDC25C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1579
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB44 is associated with a significant change in BEX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB44 is associated with a significant change in BEX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61075
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PES1 is associated with a significant change in AMTN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PES1 is associated with a significant change in AMTN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34855
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SDHAF2 and then measure expression of TUBA1B. Does this perturbation cause a significant change in TUBA1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SDHAF2 and then measure expression of TUBA1B. Does this perturbation cause a significant change in TUBA1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47214
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of CCNF is measured. Does this perturbation cause a significant change in CCNF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of CCNF is measured. Does this perturbation cause a significant change in CCNF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11060
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NHP2 is perturbed and NMU expression is quantified. Does this perturbation result in a significant change in NMU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NHP2 is perturbed and NMU expression is quantified. Does this perturbation result in a significant change in NMU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31462
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XPO1 is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XPO1 is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60382
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPS4 and examine the expression of INCENP. Does perturbing COPS4 lead to a significant change in INCENP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPS4 and examine the expression of INCENP. Does perturbing COPS4 lead to a significant change in INCENP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8921
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MED24 and monitor TMEM161B expression. Decide whether this perturbation leads to a significant alteration in TMEM161B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MED24 and monitor TMEM161B expression. Decide whether this perturbation leads to a significant alteration in TMEM161B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25648
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTOR is perturbed and the expression of RRM2 is measured. Does this perturbation cause a significant change in RRM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTOR is perturbed and the expression of RRM2 is measured. Does this perturbation cause a significant change in RRM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29140
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNOT2 is perturbed and the expression of NRG1 is measured. Determine whether NRG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNOT2 is perturbed and the expression of NRG1 is measured. Determine whether NRG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8356
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NASP is perturbed and KRT81 expression is measured. Determine whether KRT81 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NASP is perturbed and KRT81 expression is measured. Determine whether KRT81 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29959
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM4, does the expression profile of MCM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM4, does the expression profile of MCM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25177
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GIT2 is perturbed and PHF12 expression is quantified. Does this perturbation result in a significant change in PHF12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GIT2 is perturbed and PHF12 expression is quantified. Does this perturbation result in a significant change in PHF12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17902
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BOD1L1 is associated with a significant change in BOD1L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BOD1L1 is associated with a significant change in BOD1L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3725
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEPCE is associated with a significant change in ANKHD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEPCE is associated with a significant change in ANKHD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25925
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EXOSC9 and monitor GTSE1 expression. Decide whether this perturbation leads to a significant alteration in GTSE1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EXOSC9 and monitor GTSE1 expression. Decide whether this perturbation leads to a significant alteration in GTSE1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16218
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SUGP1 is perturbed and the expression of BRIP1 is measured. Determine whether BRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SUGP1 is perturbed and the expression of BRIP1 is measured. Determine whether BRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52046
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHX16 is perturbed and the expression of CDKN3 is measured. Determine whether CDKN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHX16 is perturbed and the expression of CDKN3 is measured. Determine whether CDKN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12086
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STX5 is perturbed and the expression of SPC24 is measured. Determine whether SPC24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STX5 is perturbed and the expression of SPC24 is measured. Determine whether SPC24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51936
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRCA2 is associated with a significant change in BRI3BP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRCA2 is associated with a significant change in BRI3BP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3865
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP1CA and examine the expression of NHP2. Does perturbing PPP1CA lead to a significant change in NHP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP1CA and examine the expression of NHP2. Does perturbing PPP1CA lead to a significant change in NHP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37701
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S2 is perturbed and ARMC6 expression is observed. Does this perturbation lead to a significant difference in ARMC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S2 is perturbed and ARMC6 expression is observed. Does this perturbation lead to a significant difference in ARMC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14263
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDHA1 and then measure expression of ELOVL5. Does this perturbation cause a significant change in ELOVL5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDHA1 and then measure expression of ELOVL5. Does this perturbation cause a significant change in ELOVL5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34664
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R10 is perturbed and the expression of UTP15 is measured. Determine whether UTP15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R10 is perturbed and the expression of UTP15 is measured. Determine whether UTP15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37746
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HERC1 is perturbed and the expression of HERC1 is measured. Does this perturbation cause a significant change in HERC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HERC1 is perturbed and the expression of HERC1 is measured. Does this perturbation cause a significant change in HERC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19900
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SHC1, does the expression profile of CKS1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SHC1, does the expression profile of CKS1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48247
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPG7, does the expression profile of NF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPG7, does the expression profile of NF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50807
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX46 and examine the expression of FBXO32. Does perturbing DDX46 lead to a significant change in FBXO32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX46 and examine the expression of FBXO32. Does perturbing DDX46 lead to a significant change in FBXO32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11541
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS21 is perturbed and the expression of MT-ND2 is measured. Does this perturbation cause a significant change in MT-ND2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS21 is perturbed and the expression of MT-ND2 is measured. Does this perturbation cause a significant change in MT-ND2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28420
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PET117 is perturbed and RPL22L1 expression is observed. Does this perturbation lead to a significant difference in RPL22L1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PET117 is perturbed and RPL22L1 expression is observed. Does this perturbation lead to a significant difference in RPL22L1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34873
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA8 is perturbed and the expression of EIF4EBP1 is measured. Determine whether EIF4EBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA8 is perturbed and the expression of EIF4EBP1 is measured. Determine whether EIF4EBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20856
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPS31 and monitor MRPS31 expression. Decide whether this perturbation leads to a significant alteration in MRPS31 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPS31 and monitor MRPS31 expression. Decide whether this perturbation leads to a significant alteration in MRPS31 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28688
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX24 and examine the expression of G0S2. Does perturbing DDX24 lead to a significant change in G0S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX24 and examine the expression of G0S2. Does perturbing DDX24 lead to a significant change in G0S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11391
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PET117 and examine the expression of NAT14. Does perturbing PET117 lead to a significant change in NAT14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PET117 and examine the expression of NAT14. Does perturbing PET117 lead to a significant change in NAT14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34881
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS2 and examine the expression of CDCA7. Does perturbing INTS2 lead to a significant change in CDCA7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS2 and examine the expression of CDCA7. Does perturbing INTS2 lead to a significant change in CDCA7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21911
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS11 is perturbed and FEN1 expression is measured. Determine whether FEN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS11 is perturbed and FEN1 expression is measured. Determine whether FEN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44989
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SMC3 is perturbed and PPP1R13L expression is measured. Determine whether PPP1R13L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SMC3 is perturbed and PPP1R13L expression is measured. Determine whether PPP1R13L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49159
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INO80 and then measure expression of CENPA. Does this perturbation cause a significant change in CENPA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INO80 and then measure expression of CENPA. Does this perturbation cause a significant change in CENPA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21564
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SETD2, does the expression profile of FIGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SETD2, does the expression profile of FIGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47747
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR3K is perturbed and the expression of CENPT is measured. Determine whether CENPT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR3K is perturbed and the expression of CENPT is measured. Determine whether CENPT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37196
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBM12 is perturbed and RBM12 expression is quantified. Does this perturbation result in a significant change in RBM12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBM12 is perturbed and RBM12 expression is quantified. Does this perturbation result in a significant change in RBM12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41532
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAPC1 is perturbed and the expression of KNTC1 is measured. Determine whether KNTC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAPC1 is perturbed and the expression of KNTC1 is measured. Determine whether KNTC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49536
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C12orf45 is perturbed and CKAP2L expression is quantified. Does this perturbation result in a significant change in CKAP2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C12orf45 is perturbed and CKAP2L expression is quantified. Does this perturbation result in a significant change in CKAP2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4362
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNL3 is perturbed and CDC25B expression is measured. Determine whether CDC25B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNL3 is perturbed and CDC25B expression is measured. Determine whether CDC25B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18199
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3B2 is associated with a significant change in ECM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3B2 is associated with a significant change in ECM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48005
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC1 is perturbed and XRCC2 expression is observed. Does this perturbation lead to a significant difference in XRCC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC1 is perturbed and XRCC2 expression is observed. Does this perturbation lead to a significant difference in XRCC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15753
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IMP4 and then measure expression of CCNA2. Does this perturbation cause a significant change in CCNA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IMP4 and then measure expression of CCNA2. Does this perturbation cause a significant change in CCNA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21394
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MNAT1 and examine the expression of CLSPN. Does perturbing MNAT1 lead to a significant change in CLSPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MNAT1 and examine the expression of CLSPN. Does perturbing MNAT1 lead to a significant change in CLSPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26691
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAD2L2 is perturbed and ST6GALNAC4 expression is quantified. Does this perturbation result in a significant change in ST6GALNAC4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAD2L2 is perturbed and ST6GALNAC4 expression is quantified. Does this perturbation result in a significant change in ST6GALNAC4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24562
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WBP1L and examine the expression of NNMT. Does perturbing WBP1L lead to a significant change in NNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WBP1L and examine the expression of NNMT. Does perturbing WBP1L lead to a significant change in NNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59451
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FASN is associated with a significant change in GPNMB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FASN is associated with a significant change in GPNMB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16545
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS14 and then measure expression of GTF3C6. Does this perturbation cause a significant change in GTF3C6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS14 and then measure expression of GTF3C6. Does this perturbation cause a significant change in GTF3C6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21874
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF2E2, does the expression profile of HMGN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF2E2, does the expression profile of HMGN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18887
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RNMT and then measure expression of SNHG8. Does this perturbation cause a significant change in SNHG8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RNMT and then measure expression of SNHG8. Does this perturbation cause a significant change in SNHG8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42884
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LENG8 is perturbed and SNHG21 expression is observed. Does this perturbation lead to a significant difference in SNHG21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LENG8 is perturbed and SNHG21 expression is observed. Does this perturbation lead to a significant difference in SNHG21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23813
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRNP70 is perturbed and the expression of RFC5 is measured. Does this perturbation cause a significant change in RFC5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRNP70 is perturbed and the expression of RFC5 is measured. Does this perturbation cause a significant change in RFC5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49940
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FDPS is perturbed and FDPS expression is measured. Determine whether FDPS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FDPS is perturbed and FDPS expression is measured. Determine whether FDPS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16839
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMB1 is perturbed and the expression of KIFC1 is measured. Determine whether KIFC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMB1 is perturbed and the expression of KIFC1 is measured. Determine whether KIFC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39286
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of SAMM50 is measured. Does this perturbation cause a significant change in SAMM50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of SAMM50 is measured. Does this perturbation cause a significant change in SAMM50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46560
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MOB4 is associated with a significant change in MOB4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MOB4 is associated with a significant change in MOB4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26715
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of EEF1AKMT4. Does this perturbation cause a significant change in EEF1AKMT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of EEF1AKMT4. Does this perturbation cause a significant change in EEF1AKMT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56264
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDCD6IP is perturbed and the expression of PDCD6IP is measured. Determine whether PDCD6IP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDCD6IP is perturbed and the expression of PDCD6IP is measured. Determine whether PDCD6IP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34596
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD3 is perturbed and CENPN expression is quantified. Does this perturbation result in a significant change in CENPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD3 is perturbed and CENPN expression is quantified. Does this perturbation result in a significant change in CENPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39842
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CPNE7 and examine the expression of VAMP5. Does perturbing CPNE7 lead to a significant change in VAMP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CPNE7 and examine the expression of VAMP5. Does perturbing CPNE7 lead to a significant change in VAMP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9481
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF2A1 is perturbed and the expression of TTC28-AS1 is measured. Determine whether TTC28-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF2A1 is perturbed and the expression of TTC28-AS1 is measured. Determine whether TTC28-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18776
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR36 is perturbed and the expression of CDKN2C is measured. Determine whether CDKN2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR36 is perturbed and the expression of CDKN2C is measured. Determine whether CDKN2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59756
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RCC1 and then measure expression of NUSAP1. Does this perturbation cause a significant change in NUSAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RCC1 and then measure expression of NUSAP1. Does this perturbation cause a significant change in NUSAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41994
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD1 is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD1 is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30992
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POLR2K and monitor NCAPH expression. Decide whether this perturbation leads to a significant alteration in NCAPH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POLR2K and monitor NCAPH expression. Decide whether this perturbation leads to a significant alteration in NCAPH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36888
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAB4A, does the expression profile of FIS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAB4A, does the expression profile of FIS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40797
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GFOD2 and monitor PLAT expression. Decide whether this perturbation leads to a significant alteration in PLAT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GFOD2 and monitor PLAT expression. Decide whether this perturbation leads to a significant alteration in PLAT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17758
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2B is perturbed and RCC1 expression is measured. Determine whether RCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2B is perturbed and RCC1 expression is measured. Determine whether RCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18829
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COX10 is perturbed and MGST1 expression is measured. Determine whether MGST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COX10 is perturbed and MGST1 expression is measured. Determine whether MGST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9199
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SDHA, does the expression profile of COX5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SDHA, does the expression profile of COX5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47177
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HTATSF1, does the expression profile of ZNHIT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HTATSF1, does the expression profile of ZNHIT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21017
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF7, does the expression profile of HEATR5A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF7, does the expression profile of HEATR5A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52837
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RGP1 is perturbed and the expression of LETM2 is measured. Does this perturbation cause a significant change in LETM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RGP1 is perturbed and the expression of LETM2 is measured. Does this perturbation cause a significant change in LETM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42380
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPP1R37, does the expression profile of SLC25A37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPP1R37, does the expression profile of SLC25A37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37917
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TAF13 and then measure expression of KRT18. Does this perturbation cause a significant change in KRT18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TAF13 and then measure expression of KRT18. Does this perturbation cause a significant change in KRT18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52644
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPS15 and monitor LARS2 expression. Decide whether this perturbation leads to a significant alteration in LARS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPS15 and monitor LARS2 expression. Decide whether this perturbation leads to a significant alteration in LARS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45118
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and TMED2 expression is measured. Determine whether TMED2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and TMED2 expression is measured. Determine whether TMED2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54579
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBA1 is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBA1 is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56993
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PHF5A is perturbed and BLM expression is observed. Does this perturbation lead to a significant difference in BLM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PHF5A is perturbed and BLM expression is observed. Does this perturbation lead to a significant difference in BLM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35483
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOC4, does the expression profile of DTL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOC4, does the expression profile of DTL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15857
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LAMB1 is perturbed and the expression of NUSAP1 is measured. Determine whether NUSAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LAMB1 is perturbed and the expression of NUSAP1 is measured. Determine whether NUSAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23536
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED1 is perturbed and the expression of MED1 is measured. Determine whether MED1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED1 is perturbed and the expression of MED1 is measured. Determine whether MED1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25386
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COASY is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COASY is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8482
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50699
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor TFCP2 expression. Decide whether this perturbation leads to a significant alteration in TFCP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor TFCP2 expression. Decide whether this perturbation leads to a significant alteration in TFCP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8748
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTMA and examine the expression of SNX4. Does perturbing PTMA lead to a significant change in SNX4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTMA and examine the expression of SNX4. Does perturbing PTMA lead to a significant change in SNX4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40371
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMA6 and then measure expression of SRPX. Does this perturbation cause a significant change in SRPX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMA6 and then measure expression of SRPX. Does this perturbation cause a significant change in SRPX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39224
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJA3, does the expression profile of MT-CO3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJA3, does the expression profile of MT-CO3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12537
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHAF1B is associated with a significant change in PLCXD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHAF1B is associated with a significant change in PLCXD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7195
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAA20, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAA20, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29547
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VEZT, does the expression profile of VEZT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VEZT, does the expression profile of VEZT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58867
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCNK and monitor TRAPPC5 expression. Decide whether this perturbation leads to a significant alteration in TRAPPC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCNK and monitor TRAPPC5 expression. Decide whether this perturbation leads to a significant alteration in TRAPPC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5588
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, INTS1 is perturbed and the expression of INTS1 is measured. Does this perturbation cause a significant change in INTS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, INTS1 is perturbed and the expression of INTS1 is measured. Does this perturbation cause a significant change in INTS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21730
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48833
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMB3 is perturbed and ESCO2 expression is observed. Does this perturbation lead to a significant difference in ESCO2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMB3 is perturbed and ESCO2 expression is observed. Does this perturbation lead to a significant difference in ESCO2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39333
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ACTR2 and monitor MKI67 expression. Decide whether this perturbation leads to a significant alteration in MKI67 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ACTR2 and monitor MKI67 expression. Decide whether this perturbation leads to a significant alteration in MKI67 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":688
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NPM3 is perturbed and ESM1 expression is measured. Determine whether ESM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NPM3 is perturbed and ESM1 expression is measured. Determine whether ESM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32399
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUP43 is perturbed and the expression of GFOD1 is measured. Does this perturbation cause a significant change in GFOD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUP43 is perturbed and the expression of GFOD1 is measured. Does this perturbation cause a significant change in GFOD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33240
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2H is perturbed and LEO1 expression is quantified. Does this perturbation result in a significant change in LEO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2H is perturbed and LEO1 expression is quantified. Does this perturbation result in a significant change in LEO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57222
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRKCA is perturbed and the expression of THY1 is measured. Does this perturbation cause a significant change in THY1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRKCA is perturbed and the expression of THY1 is measured. Does this perturbation cause a significant change in THY1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38490
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RTTN is perturbed and the expression of MKI67 is measured. Does this perturbation cause a significant change in MKI67 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RTTN is perturbed and the expression of MKI67 is measured. Does this perturbation cause a significant change in MKI67 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46400
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V0B and then measure expression of MSMO1. Does this perturbation cause a significant change in MSMO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V0B and then measure expression of MSMO1. Does this perturbation cause a significant change in MSMO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2784
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS7 is perturbed and the expression of MT-ND2 is measured. Does this perturbation cause a significant change in MT-ND2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS7 is perturbed and the expression of MT-ND2 is measured. Does this perturbation cause a significant change in MT-ND2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28880
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to THG1L and then measure expression of PSAT1. Does this perturbation cause a significant change in PSAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to THG1L and then measure expression of PSAT1. Does this perturbation cause a significant change in PSAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53834
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CTU2 is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CTU2 is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10226
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS2 and examine the expression of CDCA8. Does perturbing INTS2 lead to a significant change in CDCA8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS2 and examine the expression of CDCA8. Does perturbing INTS2 lead to a significant change in CDCA8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21901
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC6 and examine the expression of POLR2D. Does perturbing PSMC6 lead to a significant change in POLR2D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC6 and examine the expression of POLR2D. Does perturbing PSMC6 lead to a significant change in POLR2D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39651
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPA1 is perturbed and the expression of HNRNPA3 is measured. Determine whether HNRNPA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPA1 is perturbed and the expression of HNRNPA3 is measured. Determine whether HNRNPA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20366
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MCM5 is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MCM5 is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25202
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TM7SF2 is associated with a significant change in TM7SF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TM7SF2 is associated with a significant change in TM7SF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54485
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDHD is perturbed and DENND1A expression is observed. Does this perturbation lead to a significant difference in DENND1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDHD is perturbed and DENND1A expression is observed. Does this perturbation lead to a significant difference in DENND1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47253
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF3E and monitor MCM6 expression. Decide whether this perturbation leads to a significant alteration in MCM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF3E and monitor MCM6 expression. Decide whether this perturbation leads to a significant alteration in MCM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14408
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PUM1 is perturbed and the expression of ACSL4 is measured. Determine whether ACSL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PUM1 is perturbed and the expression of ACSL4 is measured. Determine whether ACSL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40556
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHCHD3, does the expression profile of CHCHD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHCHD3, does the expression profile of CHCHD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7267
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL17, does the expression profile of SHCBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL17, does the expression profile of SHCBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43557
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC73 is associated with a significant change in CCNB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC73 is associated with a significant change in CCNB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6335
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPMT1 and examine the expression of MDFIC. Does perturbing PTPMT1 lead to a significant change in MDFIC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPMT1 and examine the expression of MDFIC. Does perturbing PTPMT1 lead to a significant change in MDFIC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40391
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCF11 and examine the expression of DNAJC22. Does perturbing PCF11 lead to a significant change in DNAJC22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCF11 and examine the expression of DNAJC22. Does perturbing PCF11 lead to a significant change in DNAJC22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34301
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COX17 is perturbed and COX17 expression is measured. Determine whether COX17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COX17 is perturbed and COX17 expression is measured. Determine whether COX17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9279
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRPB is perturbed and TRIM7 expression is observed. Does this perturbation lead to a significant difference in TRIM7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRPB is perturbed and TRIM7 expression is observed. Does this perturbation lead to a significant difference in TRIM7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50033
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL33 is perturbed and the expression of MT-ATP8 is measured. Does this perturbation cause a significant change in MT-ATP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL33 is perturbed and the expression of MT-ATP8 is measured. Does this perturbation cause a significant change in MT-ATP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27520
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb E2F6 and monitor E2F6 expression. Decide whether this perturbation leads to a significant alteration in E2F6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb E2F6 and monitor E2F6 expression. Decide whether this perturbation leads to a significant alteration in E2F6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13538
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GEMIN8 and then measure expression of TENT4A. Does this perturbation cause a significant change in TENT4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GEMIN8 and then measure expression of TENT4A. Does this perturbation cause a significant change in TENT4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17604
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LETM1 and then measure expression of NUPR1. Does this perturbation cause a significant change in NUPR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LETM1 and then measure expression of NUPR1. Does this perturbation cause a significant change in NUPR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23854
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJA1 and then measure expression of KRT7. Does this perturbation cause a significant change in KRT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJA1 and then measure expression of KRT7. Does this perturbation cause a significant change in KRT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12504
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NOL6 and monitor TK1 expression. Decide whether this perturbation leads to a significant alteration in TK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NOL6 and monitor TK1 expression. Decide whether this perturbation leads to a significant alteration in TK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31928
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WTAP and examine the expression of CCDC85B. Does perturbing WTAP lead to a significant change in CCDC85B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WTAP and examine the expression of CCDC85B. Does perturbing WTAP lead to a significant change in CCDC85B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60321
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIFK is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIFK is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31480
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF23, does the expression profile of CDT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF23, does the expression profile of CDT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23157
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSG1 is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSG1 is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24090
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL3 is perturbed and the expression of MT-ND2 is measured. Determine whether MT-ND2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL3 is perturbed and the expression of MT-ND2 is measured. Determine whether MT-ND2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27476
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TFIP11 and monitor LRR1 expression. Decide whether this perturbation leads to a significant alteration in LRR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TFIP11 and monitor LRR1 expression. Decide whether this perturbation leads to a significant alteration in LRR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53678
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1G1 is perturbed and ATP6V1G1 expression is measured. Determine whether ATP6V1G1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1G1 is perturbed and ATP6V1G1 expression is measured. Determine whether ATP6V1G1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3039
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CASP8AP2 is perturbed and the expression of GTPBP10 is measured. Does this perturbation cause a significant change in GTPBP10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CASP8AP2 is perturbed and the expression of GTPBP10 is measured. Does this perturbation cause a significant change in GTPBP10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5030
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTC27 is perturbed and MXD3 expression is quantified. Does this perturbation result in a significant change in MXD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTC27 is perturbed and MXD3 expression is quantified. Does this perturbation result in a significant change in MXD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56162
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MCMBP and then measure expression of MCMBP. Does this perturbation cause a significant change in MCMBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MCMBP and then measure expression of MCMBP. Does this perturbation cause a significant change in MCMBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25294
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNGTT, does the expression profile of CENPI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNGTT, does the expression profile of CENPI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42847
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS7 is perturbed and MRPS7 expression is measured. Determine whether MRPS7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS7 is perturbed and MRPS7 expression is measured. Determine whether MRPS7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28869
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IPO9 and monitor IPO9 expression. Decide whether this perturbation leads to a significant alteration in IPO9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IPO9 and monitor IPO9 expression. Decide whether this perturbation leads to a significant alteration in IPO9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22208
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AAR2 is perturbed and RFC2 expression is quantified. Does this perturbation result in a significant change in RFC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AAR2 is perturbed and RFC2 expression is quantified. Does this perturbation result in a significant change in RFC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP85 and examine the expression of FAM111B. Does perturbing NUP85 lead to a significant change in FAM111B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP85 and examine the expression of FAM111B. Does perturbing NUP85 lead to a significant change in FAM111B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33341
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EEF2 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EEF2 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13829
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GUK1 and examine the expression of CDK2. Does perturbing GUK1 lead to a significant change in CDK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GUK1 and examine the expression of CDK2. Does perturbing GUK1 lead to a significant change in CDK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19371
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUVBL1 is perturbed and the expression of NBPF14 is measured. Does this perturbation cause a significant change in NBPF14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUVBL1 is perturbed and the expression of NBPF14 is measured. Does this perturbation cause a significant change in NBPF14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46420
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPTSSA and monitor CHMP7 expression. Decide whether this perturbation leads to a significant alteration in CHMP7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPTSSA and monitor CHMP7 expression. Decide whether this perturbation leads to a significant alteration in CHMP7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50908
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in TRIB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in TRIB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14245
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR43 is perturbed and the expression of LMNB1 is measured. Determine whether LMNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR43 is perturbed and the expression of LMNB1 is measured. Determine whether LMNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59806
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEP97, does the expression profile of STARD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEP97, does the expression profile of STARD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7077
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FBRSL1 is associated with a significant change in BCKDK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FBRSL1 is associated with a significant change in BCKDK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16705
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of METAP1, does the expression profile of TICAM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of METAP1, does the expression profile of TICAM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25957
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRFBP1 and monitor ZWINT expression. Decide whether this perturbation leads to a significant alteration in ZWINT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRFBP1 and monitor ZWINT expression. Decide whether this perturbation leads to a significant alteration in ZWINT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51058
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCMF1 is perturbed and the expression of CEP126 is measured. Determine whether CEP126 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCMF1 is perturbed and the expression of CEP126 is measured. Determine whether CEP126 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22796
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FBXO5 is perturbed and the expression of CEP63 is measured. Does this perturbation cause a significant change in CEP63 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FBXO5 is perturbed and the expression of CEP63 is measured. Does this perturbation cause a significant change in CEP63 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16750
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBA52 is perturbed and the expression of UBA52 is measured. Determine whether UBA52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBA52 is perturbed and the expression of UBA52 is measured. Determine whether UBA52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57096
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBE2M and then measure expression of NQO1. Does this perturbation cause a significant change in NQO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBE2M and then measure expression of NQO1. Does this perturbation cause a significant change in NQO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57324
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of CBR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of CBR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10667
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor TMSB15A expression. Decide whether this perturbation leads to a significant alteration in TMSB15A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor TMSB15A expression. Decide whether this perturbation leads to a significant alteration in TMSB15A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54258
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPR is perturbed and the expression of HNRNPR is measured. Determine whether HNRNPR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPR is perturbed and the expression of HNRNPR is measured. Determine whether HNRNPR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20556
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP1R15B is perturbed and SRP72 expression is measured. Determine whether SRP72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP1R15B is perturbed and SRP72 expression is measured. Determine whether SRP72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37859
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb WAC and monitor PLOD2 expression. Decide whether this perturbation leads to a significant alteration in PLOD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb WAC and monitor PLOD2 expression. Decide whether this perturbation leads to a significant alteration in PLOD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59338
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMUG1 and then measure expression of FBH1. Does this perturbation cause a significant change in FBH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMUG1 and then measure expression of FBH1. Does this perturbation cause a significant change in FBH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49504
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL2 is perturbed and the expression of MRPL2 is measured. Does this perturbation cause a significant change in MRPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL2 is perturbed and the expression of MRPL2 is measured. Does this perturbation cause a significant change in MRPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27210
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AAMP and then measure expression of CEP55. Does this perturbation cause a significant change in CEP55 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AAMP and then measure expression of CEP55. Does this perturbation cause a significant change in CEP55 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMA6 is perturbed and PLK1 expression is quantified. Does this perturbation result in a significant change in PLK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMA6 is perturbed and PLK1 expression is quantified. Does this perturbation result in a significant change in PLK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39212
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED4 and then measure expression of DMKN. Does this perturbation cause a significant change in DMKN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED4 and then measure expression of DMKN. Does this perturbation cause a significant change in DMKN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25754
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DCTN1 and then measure expression of CPTP. Does this perturbation cause a significant change in CPTP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DCTN1 and then measure expression of CPTP. Does this perturbation cause a significant change in CPTP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10824
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPP2R1A, does the expression profile of PPP2R1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPP2R1A, does the expression profile of PPP2R1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38057
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MDN1 is perturbed and GSR expression is quantified. Does this perturbation result in a significant change in GSR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MDN1 is perturbed and GSR expression is quantified. Does this perturbation result in a significant change in GSR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25352
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SIN3A is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SIN3A is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48350
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNOT10 and examine the expression of GGNBP2. Does perturbing CNOT10 lead to a significant change in GGNBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNOT10 and examine the expression of GGNBP2. Does perturbing CNOT10 lead to a significant change in GGNBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8281
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CENPC, does the expression profile of RREB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CENPC, does the expression profile of RREB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6747
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SHC1 is perturbed and the expression of GFOD1 is measured. Does this perturbation cause a significant change in GFOD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SHC1 is perturbed and the expression of GFOD1 is measured. Does this perturbation cause a significant change in GFOD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48260
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSF1 and monitor TIMELESS expression. Decide whether this perturbation leads to a significant alteration in TIMELESS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSF1 and monitor TIMELESS expression. Decide whether this perturbation leads to a significant alteration in TIMELESS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20748
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL44 and examine the expression of MT-ATP8. Does perturbing MRPL44 lead to a significant change in MT-ATP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL44 and examine the expression of MT-ATP8. Does perturbing MRPL44 lead to a significant change in MT-ATP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27861
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS13 and examine the expression of PCLAF. Does perturbing RPS13 lead to a significant change in PCLAF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS13 and examine the expression of PCLAF. Does perturbing RPS13 lead to a significant change in PCLAF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45041
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OIP5 and examine the expression of NUSAP1. Does perturbing OIP5 lead to a significant change in NUSAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OIP5 and examine the expression of NUSAP1. Does perturbing OIP5 lead to a significant change in NUSAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33601
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SIRT7 and examine the expression of PLP2. Does perturbing SIRT7 lead to a significant change in PLP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SIRT7 and examine the expression of PLP2. Does perturbing SIRT7 lead to a significant change in PLP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48371
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FBXW7 and examine the expression of FBXW7. Does perturbing FBXW7 lead to a significant change in FBXW7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FBXW7 and examine the expression of FBXW7. Does perturbing FBXW7 lead to a significant change in FBXW7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16771
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LIMS1 is associated with a significant change in LIMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LIMS1 is associated with a significant change in LIMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23885
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NASP and examine the expression of KRT81. Does perturbing NASP lead to a significant change in KRT81 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NASP and examine the expression of KRT81. Does perturbing NASP lead to a significant change in KRT81 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29951
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GTF2F2 and monitor MCM10 expression. Decide whether this perturbation leads to a significant alteration in MCM10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GTF2F2 and monitor MCM10 expression. Decide whether this perturbation leads to a significant alteration in MCM10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18938
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FYN, does the expression profile of TAGLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FYN, does the expression profile of TAGLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17167
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL13 is perturbed and PPRC1 expression is observed. Does this perturbation lead to a significant difference in PPRC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL13 is perturbed and PPRC1 expression is observed. Does this perturbation lead to a significant difference in PPRC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27003
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RINT1 is perturbed and the expression of RINT1 is measured. Determine whether RINT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RINT1 is perturbed and the expression of RINT1 is measured. Determine whether RINT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42436
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20844
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX8 is associated with a significant change in CREBRF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX8 is associated with a significant change in CREBRF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12255
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PIK3R4, does the expression profile of PIK3R4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PIK3R4, does the expression profile of PIK3R4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35657
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GSPT1 and monitor NNMT expression. Decide whether this perturbation leads to a significant alteration in NNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GSPT1 and monitor NNMT expression. Decide whether this perturbation leads to a significant alteration in NNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18748
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb METTL16 and monitor NAA16 expression. Decide whether this perturbation leads to a significant alteration in NAA16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb METTL16 and monitor NAA16 expression. Decide whether this perturbation leads to a significant alteration in NAA16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26088
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TADA3 is perturbed and ARPC4 expression is observed. Does this perturbation lead to a significant difference in ARPC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TADA3 is perturbed and ARPC4 expression is observed. Does this perturbation lead to a significant difference in ARPC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52503
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGBP1 is perturbed and the expression of SERPINB2 is measured. Does this perturbation cause a significant change in SERPINB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGBP1 is perturbed and the expression of SERPINB2 is measured. Does this perturbation cause a significant change in SERPINB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21280
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBCA is perturbed and TBCA expression is measured. Determine whether TBCA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBCA is perturbed and TBCA expression is measured. Determine whether TBCA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53079
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COTL1 and monitor COTL1 expression. Decide whether this perturbation leads to a significant alteration in COTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COTL1 and monitor COTL1 expression. Decide whether this perturbation leads to a significant alteration in COTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9158
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YBX3 and then measure expression of YBX3. Does this perturbation cause a significant change in YBX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YBX3 and then measure expression of YBX3. Does this perturbation cause a significant change in YBX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60724
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAA15, does the expression profile of TMPO-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAA15, does the expression profile of TMPO-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29517
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5F1C, does the expression profile of ATP5F1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5F1C, does the expression profile of ATP5F1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2527
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LTBP3 is perturbed and LTBP3 expression is observed. Does this perturbation lead to a significant difference in LTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LTBP3 is perturbed and LTBP3 expression is observed. Does this perturbation lead to a significant difference in LTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24363
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NFS1 is perturbed and the expression of PIMREG is measured. Determine whether PIMREG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NFS1 is perturbed and the expression of PIMREG is measured. Determine whether PIMREG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31326
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EMC1 is perturbed and HIST1H1B expression is quantified. Does this perturbation result in a significant change in HIST1H1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EMC1 is perturbed and HIST1H1B expression is quantified. Does this perturbation result in a significant change in HIST1H1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15222
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL27A is associated with a significant change in MDM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL27A is associated with a significant change in MDM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43885
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PFDN4, does the expression profile of CFAP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PFDN4, does the expression profile of CFAP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35027
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPP1R11 is perturbed and FANCA expression is quantified. Does this perturbation result in a significant change in FANCA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPP1R11 is perturbed and FANCA expression is quantified. Does this perturbation result in a significant change in FANCA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37792
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRPF6 and monitor DTNBP1 expression. Decide whether this perturbation leads to a significant alteration in DTNBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRPF6 and monitor DTNBP1 expression. Decide whether this perturbation leads to a significant alteration in DTNBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38958
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SDHAF2 is associated with a significant change in SDHAF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SDHAF2 is associated with a significant change in SDHAF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47195
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ADNP2 is perturbed and DDX11 expression is quantified. Does this perturbation result in a significant change in DDX11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ADNP2 is perturbed and DDX11 expression is quantified. Does this perturbation result in a significant change in DDX11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":822
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPIL2 is perturbed and TTC7A expression is measured. Determine whether TTC7A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPIL2 is perturbed and TTC7A expression is measured. Determine whether TTC7A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37619
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLR2E is perturbed and POLR2E expression is measured. Determine whether POLR2E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLR2E is perturbed and POLR2E expression is measured. Determine whether POLR2E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36729
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, USP9X is perturbed and the expression of USP9X is measured. Does this perturbation cause a significant change in USP9X expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, USP9X is perturbed and the expression of USP9X is measured. Does this perturbation cause a significant change in USP9X expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58410
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NARS and then measure expression of DDIT3. Does this perturbation cause a significant change in DDIT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NARS and then measure expression of DDIT3. Does this perturbation cause a significant change in DDIT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29904
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMG2 is associated with a significant change in FANCG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMG2 is associated with a significant change in FANCG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40115
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PFDN6 is associated with a significant change in LIAS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PFDN6 is associated with a significant change in LIAS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35075
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CYREN and examine the expression of SCG5. Does perturbing CYREN lead to a significant change in SCG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CYREN and examine the expression of SCG5. Does perturbing CYREN lead to a significant change in SCG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10581
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STXBP4 is associated with a significant change in NIBAN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STXBP4 is associated with a significant change in NIBAN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51975
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC6 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC6 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6314
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCAS2 is perturbed and RNF113A expression is measured. Determine whether RNF113A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCAS2 is perturbed and RNF113A expression is measured. Determine whether RNF113A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3419
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD2, does the expression profile of ASPM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD2, does the expression profile of ASPM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39837
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPK and examine the expression of TMPO. Does perturbing CENPK lead to a significant change in TMPO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPK and examine the expression of TMPO. Does perturbing CENPK lead to a significant change in TMPO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6891
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CYC1 is perturbed and CYC1 expression is observed. Does this perturbation lead to a significant difference in CYC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CYC1 is perturbed and CYC1 expression is observed. Does this perturbation lead to a significant difference in CYC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10483
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AURKAIP1 is associated with a significant change in POLQ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AURKAIP1 is associated with a significant change in POLQ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3205
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELL is associated with a significant change in NASP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELL is associated with a significant change in NASP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14965
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FAM32A is perturbed and the expression of MXD3 is measured. Does this perturbation cause a significant change in MXD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FAM32A is perturbed and the expression of MXD3 is measured. Does this perturbation cause a significant change in MXD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16400
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NLE1 is perturbed and PRIM1 expression is quantified. Does this perturbation result in a significant change in PRIM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NLE1 is perturbed and PRIM1 expression is quantified. Does this perturbation result in a significant change in PRIM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31632
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS9 and then measure expression of IMPA2. Does this perturbation cause a significant change in IMPA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS9 and then measure expression of IMPA2. Does this perturbation cause a significant change in IMPA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45824
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SURF6 and monitor IMPA2 expression. Decide whether this perturbation leads to a significant alteration in IMPA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SURF6 and monitor IMPA2 expression. Decide whether this perturbation leads to a significant alteration in IMPA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52308
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GPS2 is associated with a significant change in LARP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GPS2 is associated with a significant change in LARP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18565
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMG7 and then measure expression of SNHG15. Does this perturbation cause a significant change in SNHG15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMG7 and then measure expression of SNHG15. Does this perturbation cause a significant change in SNHG15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49354
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CENPA and monitor EMP1 expression. Decide whether this perturbation leads to a significant alteration in EMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CENPA and monitor EMP1 expression. Decide whether this perturbation leads to a significant alteration in EMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6718
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NAE1 is perturbed and NAE1 expression is quantified. Does this perturbation result in a significant change in NAE1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NAE1 is perturbed and NAE1 expression is quantified. Does this perturbation result in a significant change in NAE1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29732
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR12 and then measure expression of CENPM. Does this perturbation cause a significant change in CENPM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR12 and then measure expression of CENPM. Does this perturbation cause a significant change in CENPM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59574
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, VPS54 is perturbed and the expression of TUBB3 is measured. Does this perturbation cause a significant change in TUBB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, VPS54 is perturbed and the expression of TUBB3 is measured. Does this perturbation cause a significant change in TUBB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59270
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL41 is perturbed and MRPL41 expression is quantified. Does this perturbation result in a significant change in MRPL41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL41 is perturbed and MRPL41 expression is quantified. Does this perturbation result in a significant change in MRPL41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27752
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM10 and examine the expression of CDKN1A. Does perturbing TIMM10 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM10 and examine the expression of CDKN1A. Does perturbing TIMM10 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54131
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YKT6 and then measure expression of YKT6. Does this perturbation cause a significant change in YKT6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YKT6 and then measure expression of YKT6. Does this perturbation cause a significant change in YKT6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60814
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MT2A is perturbed and MT2A expression is measured. Determine whether MT2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MT2A is perturbed and MT2A expression is measured. Determine whether MT2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29049
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RAC3 and examine the expression of HERPUD1. Does perturbing RAC3 lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RAC3 and examine the expression of HERPUD1. Does perturbing RAC3 lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40971
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLE1 is perturbed and PCLAF expression is quantified. Does this perturbation result in a significant change in PCLAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLE1 is perturbed and PCLAF expression is quantified. Does this perturbation result in a significant change in PCLAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17942
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPL35 and monitor KIF2C expression. Decide whether this perturbation leads to a significant alteration in KIF2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPL35 and monitor KIF2C expression. Decide whether this perturbation leads to a significant alteration in KIF2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44128
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP39 is perturbed and the expression of EPB41L4A-AS1 is measured. Determine whether EPB41L4A-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP39 is perturbed and the expression of EPB41L4A-AS1 is measured. Determine whether EPB41L4A-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58316
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUS1 is perturbed and the expression of AC093673.1 is measured. Determine whether AC093673.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUS1 is perturbed and the expression of AC093673.1 is measured. Determine whether AC093673.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33446
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC25A3 and examine the expression of PGBD1. Does perturbing SLC25A3 lead to a significant change in PGBD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC25A3 and examine the expression of PGBD1. Does perturbing SLC25A3 lead to a significant change in PGBD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48651
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF4G2 and examine the expression of GAS5. Does perturbing EIF4G2 lead to a significant change in GAS5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF4G2 and examine the expression of GAS5. Does perturbing EIF4G2 lead to a significant change in GAS5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14781
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNRNPA1 is perturbed and HNRNPA3 expression is observed. Does this perturbation lead to a significant difference in HNRNPA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNRNPA1 is perturbed and HNRNPA3 expression is observed. Does this perturbation lead to a significant difference in HNRNPA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20363
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LIN54 is perturbed and MYL9 expression is observed. Does this perturbation lead to a significant difference in MYL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LIN54 is perturbed and MYL9 expression is observed. Does this perturbation lead to a significant difference in MYL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23913
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COX17 and monitor COX17 expression. Decide whether this perturbation leads to a significant alteration in COX17 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COX17 and monitor COX17 expression. Decide whether this perturbation leads to a significant alteration in COX17 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9278
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CTCF and then measure expression of QRICH1. Does this perturbation cause a significant change in QRICH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CTCF and then measure expression of QRICH1. Does this perturbation cause a significant change in QRICH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10054
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HJURP is perturbed and FBXO32 expression is quantified. Does this perturbation result in a significant change in FBXO32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HJURP is perturbed and FBXO32 expression is quantified. Does this perturbation result in a significant change in FBXO32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20092
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUMA1 is perturbed and SNX1 expression is observed. Does this perturbation lead to a significant difference in SNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUMA1 is perturbed and SNX1 expression is observed. Does this perturbation lead to a significant difference in SNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32973
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in SLC3A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in SLC3A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50725
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SDC1, does the expression profile of SDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SDC1, does the expression profile of SDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47117
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NMT1 is perturbed and NR2F2 expression is measured. Determine whether NR2F2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NMT1 is perturbed and NR2F2 expression is measured. Determine whether NR2F2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31709
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of KRT81. Does this perturbation cause a significant change in KRT81 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of KRT81. Does this perturbation cause a significant change in KRT81 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31044
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAF1D is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAF1D is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52692
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DPH3 is perturbed and the expression of DPH3 is measured. Determine whether DPH3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DPH3 is perturbed and the expression of DPH3 is measured. Determine whether DPH3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13016
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDX52 is perturbed and CDC6 expression is observed. Does this perturbation lead to a significant difference in CDC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDX52 is perturbed and CDC6 expression is observed. Does this perturbation lead to a significant difference in CDC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11613
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb WDR12 and monitor NUSAP1 expression. Decide whether this perturbation leads to a significant alteration in NUSAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb WDR12 and monitor NUSAP1 expression. Decide whether this perturbation leads to a significant alteration in NUSAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59568
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNRNP48, does the expression profile of AL161431.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNRNP48, does the expression profile of AL161431.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49897
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KEAP1 is perturbed and GNAI2 expression is measured. Determine whether GNAI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KEAP1 is perturbed and GNAI2 expression is measured. Determine whether GNAI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22969
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF6 is perturbed and the expression of TAF6 is measured. Does this perturbation cause a significant change in TAF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF6 is perturbed and the expression of TAF6 is measured. Does this perturbation cause a significant change in TAF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52800
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDK6 is perturbed and ECI2 expression is quantified. Does this perturbation result in a significant change in ECI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDK6 is perturbed and ECI2 expression is quantified. Does this perturbation result in a significant change in ECI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6562
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RNF103 and examine the expression of AZI2. Does perturbing RNF103 lead to a significant change in AZI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RNF103 and examine the expression of AZI2. Does perturbing RNF103 lead to a significant change in AZI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42581
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ASCC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ASCC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2195
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PABPC1 is perturbed and IL1B expression is observed. Does this perturbation lead to a significant difference in IL1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PABPC1 is perturbed and IL1B expression is observed. Does this perturbation lead to a significant difference in IL1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33943
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EXOSC1 is perturbed and the expression of DTL is measured. Does this perturbation cause a significant change in DTL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EXOSC1 is perturbed and the expression of DTL is measured. Does this perturbation cause a significant change in DTL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15960
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSME1 and examine the expression of PSME1. Does perturbing PSME1 lead to a significant change in PSME1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSME1 and examine the expression of PSME1. Does perturbing PSME1 lead to a significant change in PSME1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40021
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAB18, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAB18, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40767
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PAM16 is perturbed and TGM2 expression is observed. Does this perturbation lead to a significant difference in TGM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PAM16 is perturbed and TGM2 expression is observed. Does this perturbation lead to a significant difference in TGM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34153
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND1 and examine the expression of IGFBP3. Does perturbing CCND1 lead to a significant change in IGFBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND1 and examine the expression of IGFBP3. Does perturbing CCND1 lead to a significant change in IGFBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5511
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B5 and examine the expression of MKI67. Does perturbing EIF2B5 lead to a significant change in MKI67 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B5 and examine the expression of MKI67. Does perturbing EIF2B5 lead to a significant change in MKI67 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14191
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS2 and examine the expression of HARS. Does perturbing HARS2 lead to a significant change in HARS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS2 and examine the expression of HARS. Does perturbing HARS2 lead to a significant change in HARS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19531
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in SEC61B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in SEC61B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47375
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NSF is associated with a significant change in YIF1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NSF is associated with a significant change in YIF1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32535
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSME2 is perturbed and TJAP1 expression is quantified. Does this perturbation result in a significant change in TJAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSME2 is perturbed and TJAP1 expression is quantified. Does this perturbation result in a significant change in TJAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40062
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UTP18, does the expression profile of POP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UTP18, does the expression profile of POP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58557
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLD3 and then measure expression of SOX11. Does this perturbation cause a significant change in SOX11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLD3 and then measure expression of SOX11. Does this perturbation cause a significant change in SOX11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36324
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NARS and monitor TRIB3 expression. Decide whether this perturbation leads to a significant alteration in TRIB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NARS and monitor TRIB3 expression. Decide whether this perturbation leads to a significant alteration in TRIB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29888
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HAUS4 is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HAUS4 is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19622
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21169
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POP4, does the expression profile of RRM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POP4, does the expression profile of RRM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37287
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS10 and then measure expression of PMF1. Does this perturbation cause a significant change in PMF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS10 and then measure expression of PMF1. Does this perturbation cause a significant change in PMF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21774
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in MEST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in MEST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18295
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSTC and monitor EXOG expression. Decide whether this perturbation leads to a significant alteration in EXOG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSTC and monitor EXOG expression. Decide whether this perturbation leads to a significant alteration in EXOG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33898
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SH3KBP1 is perturbed and CDKAL1 expression is quantified. Does this perturbation result in a significant change in CDKAL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SH3KBP1 is perturbed and CDKAL1 expression is quantified. Does this perturbation result in a significant change in CDKAL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48212
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR1D and then measure expression of FANCD2. Does this perturbation cause a significant change in FANCD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR1D and then measure expression of FANCD2. Does this perturbation cause a significant change in FANCD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36564
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA0586, does the expression profile of TCF19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA0586, does the expression profile of TCF19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23007
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PALB2 is perturbed and DTL expression is measured. Determine whether DTL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PALB2 is perturbed and DTL expression is measured. Determine whether DTL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34119
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLEKHN1 is perturbed and the expression of SFRP1 is measured. Does this perturbation cause a significant change in SFRP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLEKHN1 is perturbed and the expression of SFRP1 is measured. Does this perturbation cause a significant change in SFRP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35760
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD8 and then measure expression of ERAP1. Does this perturbation cause a significant change in ERAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD8 and then measure expression of ERAP1. Does this perturbation cause a significant change in ERAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39964
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACTR8 is perturbed and the expression of AIDA is measured. Does this perturbation cause a significant change in AIDA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACTR8 is perturbed and the expression of AIDA is measured. Does this perturbation cause a significant change in AIDA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":760
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISY1, does the expression profile of FANCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISY1, does the expression profile of FANCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22397
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDT15 and examine the expression of SPP1. Does perturbing NUDT15 lead to a significant change in SPP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDT15 and examine the expression of SPP1. Does perturbing NUDT15 lead to a significant change in SPP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32861
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAPG and then measure expression of MRFAP1. Does this perturbation cause a significant change in MRFAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAPG and then measure expression of MRFAP1. Does this perturbation cause a significant change in MRFAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29854
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPA2 and examine the expression of PPA2. Does perturbing PPA2 lead to a significant change in PPA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPA2 and examine the expression of PPA2. Does perturbing PPA2 lead to a significant change in PPA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37411
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLMN is perturbed and RNF20 expression is observed. Does this perturbation lead to a significant difference in RNF20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLMN is perturbed and RNF20 expression is observed. Does this perturbation lead to a significant difference in RNF20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18023
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SMNDC1 is perturbed and SMNDC1 expression is measured. Determine whether SMNDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SMNDC1 is perturbed and SMNDC1 expression is measured. Determine whether SMNDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49459
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBLL1 is perturbed and CBLL1 expression is measured. Determine whether CBLL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBLL1 is perturbed and CBLL1 expression is measured. Determine whether CBLL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5079
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOL12 is associated with a significant change in POLA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOL12 is associated with a significant change in POLA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31905
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb VPS51 and examine the expression of PIK3R4. Does perturbing VPS51 lead to a significant change in PIK3R4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb VPS51 and examine the expression of PIK3R4. Does perturbing VPS51 lead to a significant change in PIK3R4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59241
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of LRP8 is measured. Determine whether LRP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of LRP8 is measured. Determine whether LRP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38236
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNRNPDL is perturbed and GINS2 expression is quantified. Does this perturbation result in a significant change in GINS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNRNPDL is perturbed and GINS2 expression is quantified. Does this perturbation result in a significant change in GINS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20402
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS30 is perturbed and MT-ND3 expression is quantified. Does this perturbation result in a significant change in MT-ND3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS30 is perturbed and MT-ND3 expression is quantified. Does this perturbation result in a significant change in MT-ND3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28652
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of MND1. Does perturbing MTHFD1 lead to a significant change in MND1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of MND1. Does perturbing MTHFD1 lead to a significant change in MND1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29121
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX11, does the expression profile of DEPDC1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX11, does the expression profile of DEPDC1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11147
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP9X is perturbed and NDUFS6 expression is measured. Determine whether NDUFS6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP9X is perturbed and NDUFS6 expression is measured. Determine whether NDUFS6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58439
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BRD4 and monitor GAS6 expression. Decide whether this perturbation leads to a significant alteration in GAS6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BRD4 and monitor GAS6 expression. Decide whether this perturbation leads to a significant alteration in GAS6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3918
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL18A is perturbed and the expression of WDR20 is measured. Does this perturbation cause a significant change in WDR20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL18A is perturbed and the expression of WDR20 is measured. Does this perturbation cause a significant change in WDR20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43610
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DYNC1I2 is perturbed and the expression of DYNC1I2 is measured. Does this perturbation cause a significant change in DYNC1I2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DYNC1I2 is perturbed and the expression of DYNC1I2 is measured. Does this perturbation cause a significant change in DYNC1I2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13410
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARPC2 and then measure expression of CENPW. Does this perturbation cause a significant change in CENPW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARPC2 and then measure expression of CENPW. Does this perturbation cause a significant change in CENPW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2084
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR3 is perturbed and HIST1H1B expression is measured. Determine whether HIST1H1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR3 is perturbed and HIST1H1B expression is measured. Determine whether HIST1H1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":709
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRCC1, does the expression profile of XRCC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRCC1, does the expression profile of XRCC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60447
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SBDS is perturbed and the expression of GAS5 is measured. Does this perturbation cause a significant change in GAS5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SBDS is perturbed and the expression of GAS5 is measured. Does this perturbation cause a significant change in GAS5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46870
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS9 and examine the expression of MT-CO1. Does perturbing MRPS9 lead to a significant change in MT-CO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS9 and examine the expression of MT-CO1. Does perturbing MRPS9 lead to a significant change in MT-CO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28911
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FAM50A is perturbed and FAM50A expression is quantified. Does this perturbation result in a significant change in FAM50A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FAM50A is perturbed and FAM50A expression is quantified. Does this perturbation result in a significant change in FAM50A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16412
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC3 is perturbed and THOC3 expression is measured. Determine whether THOC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC3 is perturbed and THOC3 expression is measured. Determine whether THOC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53939
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IST1 is perturbed and IST1 expression is measured. Determine whether IST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IST1 is perturbed and IST1 expression is measured. Determine whether IST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22359
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MSL1 and examine the expression of HHIP. Does perturbing MSL1 lead to a significant change in HHIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MSL1 and examine the expression of HHIP. Does perturbing MSL1 lead to a significant change in HHIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28971
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACTR3 is perturbed and the expression of EMP2 is measured. Does this perturbation cause a significant change in EMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACTR3 is perturbed and the expression of EMP2 is measured. Does this perturbation cause a significant change in EMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":710
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TPR and examine the expression of VSIR. Does perturbing TPR lead to a significant change in VSIR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TPR and examine the expression of VSIR. Does perturbing TPR lead to a significant change in VSIR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55341
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GABPA and examine the expression of CCNB1. Does perturbing GABPA lead to a significant change in CCNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GABPA and examine the expression of CCNB1. Does perturbing GABPA lead to a significant change in CCNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17211
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MCM6 is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MCM6 is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25243
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CIAO1 is perturbed and PTMS expression is observed. Does this perturbation lead to a significant difference in PTMS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CIAO1 is perturbed and PTMS expression is observed. Does this perturbation lead to a significant difference in PTMS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7723
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IMPDH2 is perturbed and DYNC1LI1 expression is quantified. Does this perturbation result in a significant change in DYNC1LI1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IMPDH2 is perturbed and DYNC1LI1 expression is quantified. Does this perturbation result in a significant change in DYNC1LI1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21462
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1A is perturbed and HMGCS1 expression is measured. Determine whether HMGCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1A is perturbed and HMGCS1 expression is measured. Determine whether HMGCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2869
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD1 is perturbed and CIT expression is observed. Does this perturbation lead to a significant difference in CIT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD1 is perturbed and CIT expression is observed. Does this perturbation lead to a significant difference in CIT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39663
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DPY19L4 is associated with a significant change in DBNDD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DPY19L4 is associated with a significant change in DBNDD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13105
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSME2 and monitor TJAP1 expression. Decide whether this perturbation leads to a significant alteration in TJAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSME2 and monitor TJAP1 expression. Decide whether this perturbation leads to a significant alteration in TJAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40068
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHC1 and then measure expression of GFOD1. Does this perturbation cause a significant change in GFOD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHC1 and then measure expression of GFOD1. Does this perturbation cause a significant change in GFOD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48264
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOP1 and then measure expression of SPAG5. Does this perturbation cause a significant change in SPAG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOP1 and then measure expression of SPAG5. Does this perturbation cause a significant change in SPAG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55054
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EPB41L2 is perturbed and MAZ expression is quantified. Does this perturbation result in a significant change in MAZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EPB41L2 is perturbed and MAZ expression is quantified. Does this perturbation result in a significant change in MAZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15442
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35A4 and examine the expression of MASTL. Does perturbing SLC35A4 lead to a significant change in MASTL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35A4 and examine the expression of MASTL. Does perturbing SLC35A4 lead to a significant change in MASTL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48691
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATIC, does the expression profile of EIF4EBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATIC, does the expression profile of EIF4EBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2327
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMA4 is perturbed and GABARAPL1 expression is measured. Determine whether GABARAPL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMA4 is perturbed and GABARAPL1 expression is measured. Determine whether GABARAPL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39199
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of HSPA9 is measured. Determine whether HSPA9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of HSPA9 is measured. Determine whether HSPA9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20886
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCMF1, does the expression profile of AACS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCMF1, does the expression profile of AACS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22777
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ILF3, does the expression profile of ILF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ILF3, does the expression profile of ILF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21367
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GEMIN6 is perturbed and UCKL1 expression is observed. Does this perturbation lead to a significant difference in UCKL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GEMIN6 is perturbed and UCKL1 expression is observed. Does this perturbation lead to a significant difference in UCKL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17533
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS17 is perturbed and MT-CO1 expression is quantified. Does this perturbation result in a significant change in MT-CO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS17 is perturbed and MT-CO1 expression is quantified. Does this perturbation result in a significant change in MT-CO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28272
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL2, does the expression profile of IFRD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL2, does the expression profile of IFRD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2357
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL9 and examine the expression of C1QL1. Does perturbing RPL9 lead to a significant change in C1QL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL9 and examine the expression of C1QL1. Does perturbing RPL9 lead to a significant change in C1QL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44591
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS14 is perturbed and the expression of RPIA is measured. Does this perturbation cause a significant change in RPIA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS14 is perturbed and the expression of RPIA is measured. Does this perturbation cause a significant change in RPIA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28210
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SP1 is associated with a significant change in SP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SP1 is associated with a significant change in SP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50465
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COX5A is perturbed and the expression of MT-ND4 is measured. Does this perturbation cause a significant change in MT-ND4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COX5A is perturbed and the expression of MT-ND4 is measured. Does this perturbation cause a significant change in MT-ND4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9310
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ESYT2, does the expression profile of PSMB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ESYT2, does the expression profile of PSMB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15687
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX19B is associated with a significant change in ALDH3B1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX19B is associated with a significant change in ALDH3B1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11275
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEMF is perturbed and KLHDC2 expression is observed. Does this perturbation lead to a significant difference in KLHDC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEMF is perturbed and KLHDC2 expression is observed. Does this perturbation lead to a significant difference in KLHDC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31193
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACTR3 is associated with a significant change in EMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACTR3 is associated with a significant change in EMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":715
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TOP1 is associated with a significant change in SPAG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TOP1 is associated with a significant change in SPAG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55055
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP1CB is perturbed and TRAPPC8 expression is measured. Determine whether TRAPPC8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP1CB is perturbed and TRAPPC8 expression is measured. Determine whether TRAPPC8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37719
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD17A and examine the expression of ABHD17A. Does perturbing ABHD17A lead to a significant change in ABHD17A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD17A and examine the expression of ABHD17A. Does perturbing ABHD17A lead to a significant change in ABHD17A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":361
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAF6 is associated with a significant change in TAF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAF6 is associated with a significant change in TAF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52805
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TFIP11 is perturbed and KNL1 expression is observed. Does this perturbation lead to a significant difference in KNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TFIP11 is perturbed and KNL1 expression is observed. Does this perturbation lead to a significant difference in KNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53693
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AHCY and monitor TMEM134 expression. Decide whether this perturbation leads to a significant alteration in TMEM134 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AHCY and monitor TMEM134 expression. Decide whether this perturbation leads to a significant alteration in TMEM134 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1018
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POT1 is associated with a significant change in MCM5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POT1 is associated with a significant change in MCM5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37365
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAD21 is perturbed and the expression of IQGAP3 is measured. Determine whether IQGAP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAD21 is perturbed and the expression of IQGAP3 is measured. Determine whether IQGAP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41056
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOL9 is perturbed and the expression of CLSPN is measured. Determine whether CLSPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOL9 is perturbed and the expression of CLSPN is measured. Determine whether CLSPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32016
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ILF2 is perturbed and ILF2 expression is quantified. Does this perturbation result in a significant change in ILF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ILF2 is perturbed and ILF2 expression is quantified. Does this perturbation result in a significant change in ILF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21332
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNRNPH1 and examine the expression of EEF1B2. Does perturbing HNRNPH1 lead to a significant change in EEF1B2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNRNPH1 and examine the expression of EEF1B2. Does perturbing HNRNPH1 lead to a significant change in EEF1B2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20451
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTBP1, does the expression profile of PTBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTBP1, does the expression profile of PTBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40257
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFS3 is perturbed and NDUFS3 expression is measured. Determine whether NDUFS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFS3 is perturbed and NDUFS3 expression is measured. Determine whether NDUFS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30909
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRC1 is perturbed and PRC1 expression is quantified. Does this perturbation result in a significant change in PRC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRC1 is perturbed and PRC1 expression is quantified. Does this perturbation result in a significant change in PRC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38252
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EXOC5 and monitor CLIC1 expression. Decide whether this perturbation leads to a significant alteration in CLIC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EXOC5 and monitor CLIC1 expression. Decide whether this perturbation leads to a significant alteration in CLIC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15878
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of DCUN1D1. Does perturbing SEC61A1 lead to a significant change in DCUN1D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of DCUN1D1. Does perturbing SEC61A1 lead to a significant change in DCUN1D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47361
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PGS1 and then measure expression of MT-ND3. Does this perturbation cause a significant change in MT-ND3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PGS1 and then measure expression of MT-ND3. Does this perturbation cause a significant change in MT-ND3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35304
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YTHDC1 is perturbed and MIR22HG expression is measured. Determine whether MIR22HG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YTHDC1 is perturbed and MIR22HG expression is measured. Determine whether MIR22HG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60909
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HUWE1 and then measure expression of ANGPTL4. Does this perturbation cause a significant change in ANGPTL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HUWE1 and then measure expression of ANGPTL4. Does this perturbation cause a significant change in ANGPTL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21084
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GEMIN5 is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GEMIN5 is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17502
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG1 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG1 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1112
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTG2 is perturbed and the expression of MT-ND3 is measured. Does this perturbation cause a significant change in MT-ND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTG2 is perturbed and the expression of MT-ND3 is measured. Does this perturbation cause a significant change in MT-ND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29070
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RNASEH2C is perturbed and the expression of EMP3 is measured. Does this perturbation cause a significant change in EMP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RNASEH2C is perturbed and the expression of EMP3 is measured. Does this perturbation cause a significant change in EMP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42550
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS9 and examine the expression of INCENP. Does perturbing RPS9 lead to a significant change in INCENP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS9 and examine the expression of INCENP. Does perturbing RPS9 lead to a significant change in INCENP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45831
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL29 is perturbed and BTBD2 expression is observed. Does this perturbation lead to a significant difference in BTBD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL29 is perturbed and BTBD2 expression is observed. Does this perturbation lead to a significant difference in BTBD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43943
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DPH2 is perturbed and the expression of FAM20C is measured. Does this perturbation cause a significant change in FAM20C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DPH2 is perturbed and the expression of FAM20C is measured. Does this perturbation cause a significant change in FAM20C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12960
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CTU2 is perturbed and the expression of PSAT1 is measured. Does this perturbation cause a significant change in PSAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CTU2 is perturbed and the expression of PSAT1 is measured. Does this perturbation cause a significant change in PSAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10210
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GRPEL1 and then measure expression of MT-ND6. Does this perturbation cause a significant change in MT-ND6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GRPEL1 and then measure expression of MT-ND6. Does this perturbation cause a significant change in MT-ND6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18604
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of USP5 is associated with a significant change in MAP1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of USP5 is associated with a significant change in MAP1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58335
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GTF3C5 and monitor RPL22L1 expression. Decide whether this perturbation leads to a significant alteration in RPL22L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GTF3C5 and monitor RPL22L1 expression. Decide whether this perturbation leads to a significant alteration in RPL22L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19248
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC2 is perturbed and SPC25 expression is observed. Does this perturbation lead to a significant difference in SPC25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC2 is perturbed and SPC25 expression is observed. Does this perturbation lead to a significant difference in SPC25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49583
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TXNL4A and examine the expression of TXNL4A. Does perturbing TXNL4A lead to a significant change in TXNL4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TXNL4A and examine the expression of TXNL4A. Does perturbing TXNL4A lead to a significant change in TXNL4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56841
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDK9 is perturbed and the expression of CLUH is measured. Determine whether CLUH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDK9 is perturbed and the expression of CLUH is measured. Determine whether CLUH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6596
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDX10 and then measure expression of UBR7. Does this perturbation cause a significant change in UBR7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDX10 and then measure expression of UBR7. Does this perturbation cause a significant change in UBR7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11124
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IPO11 and examine the expression of ZFAS1. Does perturbing IPO11 lead to a significant change in ZFAS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IPO11 and examine the expression of ZFAS1. Does perturbing IPO11 lead to a significant change in ZFAS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22131
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB1 and then measure expression of KIFC1. Does this perturbation cause a significant change in KIFC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB1 and then measure expression of KIFC1. Does this perturbation cause a significant change in KIFC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39284
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SARNP and monitor SARNP expression. Decide whether this perturbation leads to a significant alteration in SARNP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARNP and monitor SARNP expression. Decide whether this perturbation leads to a significant alteration in SARNP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46698
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CHEK1 and monitor MCM3 expression. Decide whether this perturbation leads to a significant alteration in MCM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHEK1 and monitor MCM3 expression. Decide whether this perturbation leads to a significant alteration in MCM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7378
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BMP2K and monitor SHCBP1 expression. Decide whether this perturbation leads to a significant alteration in SHCBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BMP2K and monitor SHCBP1 expression. Decide whether this perturbation leads to a significant alteration in SHCBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3648
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM199 is perturbed and the expression of PISD is measured. Determine whether PISD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM199 is perturbed and the expression of PISD is measured. Determine whether PISD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54686
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDCD11 is associated with a significant change in NEK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDCD11 is associated with a significant change in NEK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34475
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHFR and examine the expression of CXCL8. Does perturbing DHFR lead to a significant change in CXCL8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHFR and examine the expression of CXCL8. Does perturbing DHFR lead to a significant change in CXCL8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11951
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ACTR10 is perturbed and NRGN expression is observed. Does this perturbation lead to a significant difference in NRGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ACTR10 is perturbed and NRGN expression is observed. Does this perturbation lead to a significant difference in NRGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":573
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TFDP1 is perturbed and the expression of SYNE2 is measured. Does this perturbation cause a significant change in SYNE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TFDP1 is perturbed and the expression of SYNE2 is measured. Does this perturbation cause a significant change in SYNE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53660
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf53 is perturbed and DLGAP5 expression is observed. Does this perturbation lead to a significant difference in DLGAP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf53 is perturbed and DLGAP5 expression is observed. Does this perturbation lead to a significant difference in DLGAP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4453
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCNA2 is perturbed and the expression of POLD3 is measured. Determine whether POLD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCNA2 is perturbed and the expression of POLD3 is measured. Determine whether POLD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5416
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CWC22 is associated with a significant change in HAUS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CWC22 is associated with a significant change in HAUS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10365
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, INO80B is perturbed and the expression of EXOSC8 is measured. Does this perturbation cause a significant change in EXOSC8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, INO80B is perturbed and the expression of EXOSC8 is measured. Does this perturbation cause a significant change in EXOSC8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21590
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb YY1 and monitor DMKN expression. Decide whether this perturbation leads to a significant alteration in DMKN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YY1 and monitor DMKN expression. Decide whether this perturbation leads to a significant alteration in DMKN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60948
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CFL1 is perturbed and CFL1 expression is quantified. Does this perturbation result in a significant change in CFL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CFL1 is perturbed and CFL1 expression is quantified. Does this perturbation result in a significant change in CFL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7112
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS13 is associated with a significant change in RPS13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS13 is associated with a significant change in RPS13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45035
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS5 and then measure expression of MT-ND2. Does this perturbation cause a significant change in MT-ND2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS5 and then measure expression of MT-ND2. Does this perturbation cause a significant change in MT-ND2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28824
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RCCD1 is perturbed and the expression of NID2 is measured. Determine whether NID2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RCCD1 is perturbed and the expression of NID2 is measured. Determine whether NID2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42026
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GOLT1B is perturbed and GOLT1B expression is quantified. Does this perturbation result in a significant change in GOLT1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GOLT1B is perturbed and GOLT1B expression is quantified. Does this perturbation result in a significant change in GOLT1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18312
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PIAS1 is perturbed and RFFL expression is observed. Does this perturbation lead to a significant difference in RFFL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PIAS1 is perturbed and RFFL expression is observed. Does this perturbation lead to a significant difference in RFFL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35523
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ORC5 is perturbed and SLC25A37 expression is quantified. Does this perturbation result in a significant change in SLC25A37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ORC5 is perturbed and SLC25A37 expression is quantified. Does this perturbation result in a significant change in SLC25A37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33762
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMA16 and then measure expression of ARNTL2. Does this perturbation cause a significant change in ARNTL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMA16 and then measure expression of ARNTL2. Does this perturbation cause a significant change in ARNTL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54534
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ALG14 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ALG14 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1178
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R15B is perturbed and the expression of PCBD1 is measured. Determine whether PCBD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R15B is perturbed and the expression of PCBD1 is measured. Determine whether PCBD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37836
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFB7 is perturbed and PEX13 expression is quantified. Does this perturbation result in a significant change in PEX13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFB7 is perturbed and PEX13 expression is quantified. Does this perturbation result in a significant change in PEX13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30862
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSE1L is perturbed and PCLAF expression is observed. Does this perturbation lead to a significant difference in PCLAF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSE1L is perturbed and PCLAF expression is observed. Does this perturbation lead to a significant difference in PCLAF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9873
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UXT and examine the expression of TRIM5. Does perturbing UXT lead to a significant change in TRIM5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UXT and examine the expression of TRIM5. Does perturbing UXT lead to a significant change in TRIM5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58761
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPG1 and examine the expression of PDE1C. Does perturbing COPG1 lead to a significant change in PDE1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPG1 and examine the expression of PDE1C. Does perturbing COPG1 lead to a significant change in PDE1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8841
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DTYMK and monitor DTYMK expression. Decide whether this perturbation leads to a significant alteration in DTYMK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DTYMK and monitor DTYMK expression. Decide whether this perturbation leads to a significant alteration in DTYMK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13328
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTV1 and examine the expression of TIPIN. Does perturbing LTV1 lead to a significant change in TIPIN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTV1 and examine the expression of TIPIN. Does perturbing LTV1 lead to a significant change in TIPIN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24431
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SART1 is perturbed and DNMT1 expression is quantified. Does this perturbation result in a significant change in DNMT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SART1 is perturbed and DNMT1 expression is quantified. Does this perturbation result in a significant change in DNMT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46792
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KRT8 and then measure expression of RALGAPA1. Does this perturbation cause a significant change in RALGAPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KRT8 and then measure expression of RALGAPA1. Does this perturbation cause a significant change in RALGAPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23454
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YTHDC1 and then measure expression of MTHFD2L. Does this perturbation cause a significant change in MTHFD2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YTHDC1 and then measure expression of MTHFD2L. Does this perturbation cause a significant change in MTHFD2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60924
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TACC3 and then measure expression of EIF2D. Does this perturbation cause a significant change in EIF2D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TACC3 and then measure expression of EIF2D. Does this perturbation cause a significant change in EIF2D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52434
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBAP1 is perturbed and UBAP1 expression is measured. Determine whether UBAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBAP1 is perturbed and UBAP1 expression is measured. Determine whether UBAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57129
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STT3B and monitor NIBAN1 expression. Decide whether this perturbation leads to a significant alteration in NIBAN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STT3B and monitor NIBAN1 expression. Decide whether this perturbation leads to a significant alteration in NIBAN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51878
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS6 is perturbed and MRPS6 expression is quantified. Does this perturbation result in a significant change in MRPS6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS6 is perturbed and MRPS6 expression is quantified. Does this perturbation result in a significant change in MRPS6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28832
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and STMN1 expression is measured. Determine whether STMN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and STMN1 expression is measured. Determine whether STMN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17419
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC5 and examine the expression of ANAPC5. Does perturbing ANAPC5 lead to a significant change in ANAPC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC5 and examine the expression of ANAPC5. Does perturbing ANAPC5 lead to a significant change in ANAPC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1441
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMG3 is perturbed and TGM2 expression is quantified. Does this perturbation result in a significant change in TGM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMG3 is perturbed and TGM2 expression is quantified. Does this perturbation result in a significant change in TGM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40142
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HEATR1 is perturbed and the expression of ARHGAP11A is measured. Does this perturbation cause a significant change in ARHGAP11A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HEATR1 is perturbed and the expression of ARHGAP11A is measured. Does this perturbation cause a significant change in ARHGAP11A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19850
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DGCR8, does the expression profile of CENPJ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DGCR8, does the expression profile of CENPJ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11887
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD7 is associated with a significant change in TRIM7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD7 is associated with a significant change in TRIM7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39955
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP19 is perturbed and the expression of MMS22L is measured. Determine whether MMS22L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP19 is perturbed and the expression of MMS22L is measured. Determine whether MMS22L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51096
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MBIP and then measure expression of QTRT1. Does this perturbation cause a significant change in QTRT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MBIP and then measure expression of QTRT1. Does this perturbation cause a significant change in QTRT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24874
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNF8 is associated with a significant change in FAM162A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNF8 is associated with a significant change in FAM162A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49705
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which INTS10 is perturbed and INTS10 expression is observed. Does this perturbation lead to a significant difference in INTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which INTS10 is perturbed and INTS10 expression is observed. Does this perturbation lead to a significant difference in INTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21763
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3C1 and then measure expression of GTF3C1. Does this perturbation cause a significant change in GTF3C1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3C1 and then measure expression of GTF3C1. Does this perturbation cause a significant change in GTF3C1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19114
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AAAS is perturbed and FBXO28 expression is quantified. Does this perturbation result in a significant change in FBXO28 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AAAS is perturbed and FBXO28 expression is quantified. Does this perturbation result in a significant change in FBXO28 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA8 and then measure expression of TMED3. Does this perturbation cause a significant change in TMED3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA8 and then measure expression of TMED3. Does this perturbation cause a significant change in TMED3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20874
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBCA is perturbed and SRP19 expression is measured. Determine whether SRP19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBCA is perturbed and SRP19 expression is measured. Determine whether SRP19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53089
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ABCF1 is perturbed and the expression of IFRD1 is measured. Does this perturbation cause a significant change in IFRD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ABCF1 is perturbed and the expression of IFRD1 is measured. Does this perturbation cause a significant change in IFRD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":320
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP6V0C is associated with a significant change in HMGCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP6V0C is associated with a significant change in HMGCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2805
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FDXR is perturbed and the expression of FHL2 is measured. Determine whether FHL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FDXR is perturbed and the expression of FHL2 is measured. Determine whether FHL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16876
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PHF5A is associated with a significant change in IMPA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PHF5A is associated with a significant change in IMPA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35465
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UNC50 is perturbed and CETN3 expression is observed. Does this perturbation lead to a significant difference in CETN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UNC50 is perturbed and CETN3 expression is observed. Does this perturbation lead to a significant difference in CETN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57763
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPH1 is perturbed and HNRNPH1 expression is measured. Determine whether HNRNPH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPH1 is perturbed and HNRNPH1 expression is measured. Determine whether HNRNPH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20449
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX46 is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX46 is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11532
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCT3 is associated with a significant change in CCT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCT3 is associated with a significant change in CCT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5745
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF1D is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF1D is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52690
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAA38, does the expression profile of CDKN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAA38, does the expression profile of CDKN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29647
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of PLIN2 is measured. Does this perturbation cause a significant change in PLIN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of PLIN2 is measured. Does this perturbation cause a significant change in PLIN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53420
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNOT9 and then measure expression of POLD1. Does this perturbation cause a significant change in POLD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNOT9 and then measure expression of POLD1. Does this perturbation cause a significant change in POLD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8414
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SASS6 is perturbed and FANCD2 expression is quantified. Does this perturbation result in a significant change in FANCD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SASS6 is perturbed and FANCD2 expression is quantified. Does this perturbation result in a significant change in FANCD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46832
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SFPQ is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SFPQ is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48142
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MALSU1 is perturbed and MALSU1 expression is quantified. Does this perturbation result in a significant change in MALSU1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MALSU1 is perturbed and MALSU1 expression is quantified. Does this perturbation result in a significant change in MALSU1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24632
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SKA1 is perturbed and the expression of SPATA5L1 is measured. Does this perturbation cause a significant change in SPATA5L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SKA1 is perturbed and the expression of SPATA5L1 is measured. Does this perturbation cause a significant change in SPATA5L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48400
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VPS13D, does the expression profile of HELLS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VPS13D, does the expression profile of HELLS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58967
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PAM16 and monitor TGM2 expression. Decide whether this perturbation leads to a significant alteration in TGM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PAM16 and monitor TGM2 expression. Decide whether this perturbation leads to a significant alteration in TGM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34158
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BOP1, does the expression profile of POLRMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BOP1, does the expression profile of POLRMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3777
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNOT1 is perturbed and CDKN2B expression is quantified. Does this perturbation result in a significant change in CDKN2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNOT1 is perturbed and CDKN2B expression is quantified. Does this perturbation result in a significant change in CDKN2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8252
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBM17 is associated with a significant change in RBM17 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBM17 is associated with a significant change in RBM17 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41555
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SSRP1 is perturbed and CENPH expression is observed. Does this perturbation lead to a significant difference in CENPH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SSRP1 is perturbed and CENPH expression is observed. Does this perturbation lead to a significant difference in CENPH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51683
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS12 and examine the expression of TUBB3. Does perturbing INTS12 lead to a significant change in TUBB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS12 and examine the expression of TUBB3. Does perturbing INTS12 lead to a significant change in TUBB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21811
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PALB2 and monitor CC2D1B expression. Decide whether this perturbation leads to a significant alteration in CC2D1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PALB2 and monitor CC2D1B expression. Decide whether this perturbation leads to a significant alteration in CC2D1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34138
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OIP5 is perturbed and the expression of NUSAP1 is measured. Determine whether NUSAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OIP5 is perturbed and the expression of NUSAP1 is measured. Determine whether NUSAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33606
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5PD is perturbed and ATP5PD expression is quantified. Does this perturbation result in a significant change in ATP5PD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5PD is perturbed and ATP5PD expression is quantified. Does this perturbation result in a significant change in ATP5PD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2642
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDCD7 is perturbed and the expression of MCM10 is measured. Does this perturbation cause a significant change in MCM10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDCD7 is perturbed and the expression of MCM10 is measured. Does this perturbation cause a significant change in MCM10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34640
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEPHS2 is associated with a significant change in SEPHS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEPHS2 is associated with a significant change in SEPHS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47585
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OIP5 and then measure expression of TOP2A. Does this perturbation cause a significant change in TOP2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OIP5 and then measure expression of TOP2A. Does this perturbation cause a significant change in TOP2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33624
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR3 is perturbed and SYNE2 expression is measured. Determine whether SYNE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR3 is perturbed and SYNE2 expression is measured. Determine whether SYNE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59679
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC7A5 and examine the expression of GOLGA4. Does perturbing SLC7A5 lead to a significant change in GOLGA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC7A5 and examine the expression of GOLGA4. Does perturbing SLC7A5 lead to a significant change in GOLGA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48881
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS21 is perturbed and the expression of NUSAP1 is measured. Does this perturbation cause a significant change in NUSAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS21 is perturbed and the expression of NUSAP1 is measured. Does this perturbation cause a significant change in NUSAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45350
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAMLG is perturbed and CAMLG expression is quantified. Does this perturbation result in a significant change in CAMLG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAMLG is perturbed and CAMLG expression is quantified. Does this perturbation result in a significant change in CAMLG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4862
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNRD1 and monitor ESCO2 expression. Decide whether this perturbation leads to a significant alteration in ESCO2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNRD1 and monitor ESCO2 expression. Decide whether this perturbation leads to a significant alteration in ESCO2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61938
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RBM19 and monitor CCNA2 expression. Decide whether this perturbation leads to a significant alteration in CCNA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RBM19 and monitor CCNA2 expression. Decide whether this perturbation leads to a significant alteration in CCNA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41588
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPAG7, does the expression profile of SPAG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPAG7, does the expression profile of SPAG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50527
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GTF3C1 and monitor PSAT1 expression. Decide whether this perturbation leads to a significant alteration in PSAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GTF3C1 and monitor PSAT1 expression. Decide whether this perturbation leads to a significant alteration in PSAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19138
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMA16 and then measure expression of MCM6. Does this perturbation cause a significant change in MCM6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMA16 and then measure expression of MCM6. Does this perturbation cause a significant change in MCM6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54524
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C12orf45 is associated with a significant change in NCAPG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C12orf45 is associated with a significant change in NCAPG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4375
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PUM1 and then measure expression of PUM1. Does this perturbation cause a significant change in PUM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PUM1 and then measure expression of PUM1. Does this perturbation cause a significant change in PUM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40534
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HIPK1 is perturbed and PRDX1 expression is quantified. Does this perturbation result in a significant change in PRDX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HIPK1 is perturbed and PRDX1 expression is quantified. Does this perturbation result in a significant change in PRDX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19982
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP6 is perturbed and the expression of CXCL8 is measured. Does this perturbation cause a significant change in CXCL8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP6 is perturbed and the expression of CXCL8 is measured. Does this perturbation cause a significant change in CXCL8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7560
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD14 is perturbed and GABARAPL1 expression is quantified. Does this perturbation result in a significant change in GABARAPL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD14 is perturbed and GABARAPL1 expression is quantified. Does this perturbation result in a significant change in GABARAPL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39782
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TXNL4A is perturbed and TXNL4A expression is observed. Does this perturbation lead to a significant difference in TXNL4A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TXNL4A is perturbed and TXNL4A expression is observed. Does this perturbation lead to a significant difference in TXNL4A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56843
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INO80 is associated with a significant change in ASF1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INO80 is associated with a significant change in ASF1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21545
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLD3, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLD3, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36317
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHX8 is perturbed and CREBRF expression is quantified. Does this perturbation result in a significant change in CREBRF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHX8 is perturbed and CREBRF expression is quantified. Does this perturbation result in a significant change in CREBRF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12252
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTCD3, does the expression profile of SLF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTCD3, does the expression profile of SLF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40277
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPE is associated with a significant change in ZMYM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPE is associated with a significant change in ZMYM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8815
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HAUS4 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HAUS4 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19639
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL1 and examine the expression of MT-ND2. Does perturbing MRPL1 lead to a significant change in MT-ND2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL1 and examine the expression of MT-ND2. Does perturbing MRPL1 lead to a significant change in MT-ND2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26921
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B10 is associated with a significant change in HSD17B10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B10 is associated with a significant change in HSD17B10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20675
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNOT11, does the expression profile of MZT2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNOT11, does the expression profile of MZT2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8317
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNRPC and monitor PCLAF expression. Decide whether this perturbation leads to a significant alteration in PCLAF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNRPC and monitor PCLAF expression. Decide whether this perturbation leads to a significant alteration in PCLAF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50058
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPK and then measure expression of ATP5F1D. Does this perturbation cause a significant change in ATP5F1D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPK and then measure expression of ATP5F1D. Does this perturbation cause a significant change in ATP5F1D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20474
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF2E1, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF2E1, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18857
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL10A and then measure expression of RPL10A. Does this perturbation cause a significant change in RPL10A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL10A and then measure expression of RPL10A. Does this perturbation cause a significant change in RPL10A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43344
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFA6 is perturbed and NDUFA6 expression is observed. Does this perturbation lead to a significant difference in NDUFA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFA6 is perturbed and NDUFA6 expression is observed. Does this perturbation lead to a significant difference in NDUFA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30543
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRRM2 and examine the expression of ZNF580. Does perturbing SRRM2 lead to a significant change in ZNF580 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRRM2 and examine the expression of ZNF580. Does perturbing SRRM2 lead to a significant change in ZNF580 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51311
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX1 is perturbed and PSAT1 expression is measured. Determine whether PSAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX1 is perturbed and PSAT1 expression is measured. Determine whether PSAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11099
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCNK is associated with a significant change in CCNK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCNK is associated with a significant change in CCNK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5595
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of TMSB15A is measured. Determine whether TMSB15A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of TMSB15A is measured. Determine whether TMSB15A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54256
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAB4B is associated with a significant change in USP14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAB4B is associated with a significant change in USP14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40815
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPP1R2 and monitor NUPR1 expression. Decide whether this perturbation leads to a significant alteration in NUPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPP1R2 and monitor NUPR1 expression. Decide whether this perturbation leads to a significant alteration in NUPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37878
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LONP1 is perturbed and the expression of MT-CYB is measured. Determine whether MT-CYB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LONP1 is perturbed and the expression of MT-CYB is measured. Determine whether MT-CYB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23956
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDX51 and monitor PPTC7 expression. Decide whether this perturbation leads to a significant alteration in PPTC7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDX51 and monitor PPTC7 expression. Decide whether this perturbation leads to a significant alteration in PPTC7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11588
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, H3F3A is perturbed and CRYL1 expression is measured. Determine whether CRYL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, H3F3A is perturbed and CRYL1 expression is measured. Determine whether CRYL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19499
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ADRM1 is perturbed and the expression of MLLT11 is measured. Does this perturbation cause a significant change in MLLT11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ADRM1 is perturbed and the expression of MLLT11 is measured. Does this perturbation cause a significant change in MLLT11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":860
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCBP2 is perturbed and the expression of KNTC1 is measured. Determine whether KNTC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCBP2 is perturbed and the expression of KNTC1 is measured. Determine whether KNTC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30246
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPLP0 is associated with a significant change in PCLAF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPLP0 is associated with a significant change in PCLAF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44615
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZCCHC9 is associated with a significant change in ZWINT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZCCHC9 is associated with a significant change in ZWINT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61185
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PAK1IP1 is perturbed and UBE2T expression is observed. Does this perturbation lead to a significant difference in UBE2T expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PAK1IP1 is perturbed and UBE2T expression is observed. Does this perturbation lead to a significant difference in UBE2T expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34083
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARS2 is perturbed and the expression of GMEB1 is measured. Determine whether GMEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARS2 is perturbed and the expression of GMEB1 is measured. Determine whether GMEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16466
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CAMLG and monitor KDELR3 expression. Decide whether this perturbation leads to a significant alteration in KDELR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CAMLG and monitor KDELR3 expression. Decide whether this perturbation leads to a significant alteration in KDELR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4878
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RACK1 is perturbed and the expression of GINS2 is measured. Determine whether GINS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RACK1 is perturbed and the expression of GINS2 is measured. Determine whether GINS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40996
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CRNKL1 and monitor THYN1 expression. Decide whether this perturbation leads to a significant alteration in THYN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CRNKL1 and monitor THYN1 expression. Decide whether this perturbation leads to a significant alteration in THYN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9808
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CABIN1 is perturbed and BTG3 expression is measured. Determine whether BTG3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CABIN1 is perturbed and BTG3 expression is measured. Determine whether BTG3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4759
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP6V1G1 is perturbed and HMGCS1 expression is quantified. Does this perturbation result in a significant change in HMGCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP6V1G1 is perturbed and HMGCS1 expression is quantified. Does this perturbation result in a significant change in HMGCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3042
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRRM1 is perturbed and LAMTOR4 expression is measured. Determine whether LAMTOR4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRRM1 is perturbed and LAMTOR4 expression is measured. Determine whether LAMTOR4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51299
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KRI1 is perturbed and the expression of MXD3 is measured. Determine whether MXD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KRI1 is perturbed and the expression of MXD3 is measured. Determine whether MXD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23366
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL21 and then measure expression of NPRL3. Does this perturbation cause a significant change in NPRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL21 and then measure expression of NPRL3. Does this perturbation cause a significant change in NPRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27284
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CD3EAP is perturbed and the expression of CKAP2L is measured. Determine whether CKAP2L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CD3EAP is perturbed and the expression of CKAP2L is measured. Determine whether CKAP2L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5946
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MALSU1, does the expression profile of MT-ND2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MALSU1, does the expression profile of MT-ND2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24657
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF3C3, does the expression profile of TNNT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF3C3, does the expression profile of TNNT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19187
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP19 is perturbed and CYB5R4 expression is measured. Determine whether CYB5R4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP19 is perturbed and CYB5R4 expression is measured. Determine whether CYB5R4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51119
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR82 is perturbed and the expression of PSMC3IP is measured. Does this perturbation cause a significant change in PSMC3IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR82 is perturbed and the expression of PSMC3IP is measured. Does this perturbation cause a significant change in PSMC3IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60130
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HLA-C and examine the expression of BDH1. Does perturbing HLA-C lead to a significant change in BDH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HLA-C and examine the expression of BDH1. Does perturbing HLA-C lead to a significant change in BDH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20111
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YBX3, does the expression profile of CDC123 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YBX3, does the expression profile of CDC123 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60747
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor CEP97 expression. Decide whether this perturbation leads to a significant alteration in CEP97 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor CEP97 expression. Decide whether this perturbation leads to a significant alteration in CEP97 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16518
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS5 is perturbed and the expression of PIMREG is measured. Determine whether PIMREG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS5 is perturbed and the expression of PIMREG is measured. Determine whether PIMREG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22016
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MFN2 is perturbed and HMOX1 expression is observed. Does this perturbation lead to a significant difference in HMOX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MFN2 is perturbed and HMOX1 expression is observed. Does this perturbation lead to a significant difference in HMOX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26263
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KATNB1 is perturbed and PIGV expression is measured. Determine whether PIGV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KATNB1 is perturbed and PIGV expression is measured. Determine whether PIGV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22749
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HAUS3 and examine the expression of WRAP53. Does perturbing HAUS3 lead to a significant change in WRAP53 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HAUS3 and examine the expression of WRAP53. Does perturbing HAUS3 lead to a significant change in WRAP53 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19611
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS2 is perturbed and HARS expression is quantified. Does this perturbation result in a significant change in HARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS2 is perturbed and HARS expression is quantified. Does this perturbation result in a significant change in HARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19532
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR1C is perturbed and the expression of AMTN is measured. Determine whether AMTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR1C is perturbed and the expression of AMTN is measured. Determine whether AMTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36536
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KANSL1 is associated with a significant change in C16orf58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KANSL1 is associated with a significant change in C16orf58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22545
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CPOX and examine the expression of PLAAT4. Does perturbing CPOX lead to a significant change in PLAAT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CPOX and examine the expression of PLAAT4. Does perturbing CPOX lead to a significant change in PLAAT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9521
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX46 and examine the expression of ZMAT3. Does perturbing DDX46 lead to a significant change in ZMAT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX46 and examine the expression of ZMAT3. Does perturbing DDX46 lead to a significant change in ZMAT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11531
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RINT1 and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RINT1 and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42444
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and PSAT1 expression is observed. Does this perturbation lead to a significant difference in PSAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and PSAT1 expression is observed. Does this perturbation lead to a significant difference in PSAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48733
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DONSON is associated with a significant change in UCP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DONSON is associated with a significant change in UCP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12915
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR3H is perturbed and the expression of CDC25A is measured. Determine whether CDC25A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR3H is perturbed and the expression of CDC25A is measured. Determine whether CDC25A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37146
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EWSR1 is perturbed and the expression of FGF1 is measured. Does this perturbation cause a significant change in FGF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EWSR1 is perturbed and the expression of FGF1 is measured. Does this perturbation cause a significant change in FGF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15730
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DRAP1 is perturbed and C11orf68 expression is quantified. Does this perturbation result in a significant change in C11orf68 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DRAP1 is perturbed and C11orf68 expression is quantified. Does this perturbation result in a significant change in C11orf68 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13152
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMB5 and monitor HSPA1A expression. Decide whether this perturbation leads to a significant alteration in HSPA1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMB5 and monitor HSPA1A expression. Decide whether this perturbation leads to a significant alteration in HSPA1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39418
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL37 is associated with a significant change in ATP13A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL37 is associated with a significant change in ATP13A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44265
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCKAP1 is perturbed and the expression of IDS is measured. Determine whether IDS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCKAP1 is perturbed and the expression of IDS is measured. Determine whether IDS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30286
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GOLT1B and monitor YIF1A expression. Decide whether this perturbation leads to a significant alteration in YIF1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GOLT1B and monitor YIF1A expression. Decide whether this perturbation leads to a significant alteration in YIF1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18328
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCAPH is associated with a significant change in ABRAXAS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCAPH is associated with a significant change in ABRAXAS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30175
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL42 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL42 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27798
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP2A2 is associated with a significant change in ATP2A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP2A2 is associated with a significant change in ATP2A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2435
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PNN is associated with a significant change in CENPW expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PNN is associated with a significant change in CENPW expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36045
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLA2 and then measure expression of MEN1. Does this perturbation cause a significant change in MEN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLA2 and then measure expression of MEN1. Does this perturbation cause a significant change in MEN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36234
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3A is perturbed and GTF3A expression is quantified. Does this perturbation result in a significant change in GTF3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3A is perturbed and GTF3A expression is quantified. Does this perturbation result in a significant change in GTF3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19082
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBA1, does the expression profile of UBA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBA1, does the expression profile of UBA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56987
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RCOR1 is perturbed and SPP1 expression is measured. Determine whether SPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RCOR1 is perturbed and SPP1 expression is measured. Determine whether SPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42089
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2L and examine the expression of CEP192. Does perturbing POLR2L lead to a significant change in CEP192 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2L and examine the expression of CEP192. Does perturbing POLR2L lead to a significant change in CEP192 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36901
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, THAP11 is perturbed and AL445524.1 expression is quantified. Does this perturbation result in a significant change in AL445524.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, THAP11 is perturbed and AL445524.1 expression is quantified. Does this perturbation result in a significant change in AL445524.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53812
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUB1 is perturbed and OLA1 expression is observed. Does this perturbation lead to a significant difference in OLA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUB1 is perturbed and OLA1 expression is observed. Does this perturbation lead to a significant difference in OLA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32703
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS15, does the expression profile of TMSB15A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS15, does the expression profile of TMSB15A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45097
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBGCP5 and examine the expression of MKI67. Does perturbing TUBGCP5 lead to a significant change in MKI67 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBGCP5 and examine the expression of MKI67. Does perturbing TUBGCP5 lead to a significant change in MKI67 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56631
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTR1A is perturbed and the expression of ACTR1A is measured. Determine whether ACTR1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTR1A is perturbed and the expression of ACTR1A is measured. Determine whether ACTR1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":616
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS20 is perturbed and the expression of ASPM is measured. Does this perturbation cause a significant change in ASPM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS20 is perturbed and the expression of ASPM is measured. Does this perturbation cause a significant change in ASPM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45300
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RNF20 and examine the expression of MARCKSL1. Does perturbing RNF20 lead to a significant change in MARCKSL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RNF20 and examine the expression of MARCKSL1. Does perturbing RNF20 lead to a significant change in MARCKSL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42701
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRTO4 is perturbed and DNA2 expression is quantified. Does this perturbation result in a significant change in DNA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRTO4 is perturbed and DNA2 expression is quantified. Does this perturbation result in a significant change in DNA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28942
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUDC is perturbed and AURKB expression is observed. Does this perturbation lead to a significant difference in AURKB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUDC is perturbed and AURKB expression is observed. Does this perturbation lead to a significant difference in AURKB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32813
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ESYT1 is perturbed and MAP1A expression is observed. Does this perturbation lead to a significant difference in MAP1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ESYT1 is perturbed and MAP1A expression is observed. Does this perturbation lead to a significant difference in MAP1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15643
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UQCRQ is perturbed and PODXL expression is observed. Does this perturbation lead to a significant difference in PODXL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UQCRQ is perturbed and PODXL expression is observed. Does this perturbation lead to a significant difference in PODXL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58043
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PI4KA is perturbed and RHOB expression is quantified. Does this perturbation result in a significant change in RHOB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PI4KA is perturbed and RHOB expression is quantified. Does this perturbation result in a significant change in RHOB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35492
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FYN is associated with a significant change in TAGLN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FYN is associated with a significant change in TAGLN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17165
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SART3 is perturbed and DNMT1 expression is measured. Determine whether DNMT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SART3 is perturbed and DNMT1 expression is measured. Determine whether DNMT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46809
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of NUDT1 is measured. Determine whether NUDT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of NUDT1 is measured. Determine whether NUDT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46726
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of EEF1AKMT4 is measured. Does this perturbation cause a significant change in EEF1AKMT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of EEF1AKMT4 is measured. Does this perturbation cause a significant change in EEF1AKMT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56260
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPS26 and monitor MT-CO1 expression. Decide whether this perturbation leads to a significant alteration in MT-CO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPS26 and monitor MT-CO1 expression. Decide whether this perturbation leads to a significant alteration in MT-CO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28578
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSCB is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSCB is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20640
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPIL1 is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPIL1 is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37589
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACTR1A is perturbed and the expression of EVL is measured. Does this perturbation cause a significant change in EVL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACTR1A is perturbed and the expression of EVL is measured. Does this perturbation cause a significant change in EVL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":600
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and RRM1 expression is quantified. Does this perturbation result in a significant change in RRM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and RRM1 expression is quantified. Does this perturbation result in a significant change in RRM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46712
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2H and examine the expression of UBE2H. Does perturbing UBE2H lead to a significant change in UBE2H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2H and examine the expression of UBE2H. Does perturbing UBE2H lead to a significant change in UBE2H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57211
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HPS5 and examine the expression of HEATR6. Does perturbing HPS5 lead to a significant change in HEATR6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HPS5 and examine the expression of HEATR6. Does perturbing HPS5 lead to a significant change in HEATR6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20631
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPA2 is perturbed and CCNA2 expression is measured. Determine whether CCNA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPA2 is perturbed and CCNA2 expression is measured. Determine whether CCNA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43049
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of METTL1 is associated with a significant change in ACAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of METTL1 is associated with a significant change in ACAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26035
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PNKP and examine the expression of PNKP. Does perturbing PNKP lead to a significant change in PNKP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PNKP and examine the expression of PNKP. Does perturbing PNKP lead to a significant change in PNKP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36021
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRRM1 and monitor LAMTOR4 expression. Decide whether this perturbation leads to a significant alteration in LAMTOR4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRRM1 and monitor LAMTOR4 expression. Decide whether this perturbation leads to a significant alteration in LAMTOR4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51298
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SDAD1 and monitor DOCK10 expression. Decide whether this perturbation leads to a significant alteration in DOCK10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SDAD1 and monitor DOCK10 expression. Decide whether this perturbation leads to a significant alteration in DOCK10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47098
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPIH is associated with a significant change in HIST1H2AH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPIH is associated with a significant change in HIST1H2AH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37535
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CTDP1 and then measure expression of NMU. Does this perturbation cause a significant change in NMU expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CTDP1 and then measure expression of NMU. Does this perturbation cause a significant change in NMU expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10104
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LTBP3 is associated with a significant change in PLAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LTBP3 is associated with a significant change in PLAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24385
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCAPH is perturbed and POLR1E expression is measured. Determine whether POLR1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCAPH is perturbed and POLR1E expression is measured. Determine whether POLR1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30159
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DCTN2 and monitor PRC1 expression. Decide whether this perturbation leads to a significant alteration in PRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DCTN2 and monitor PRC1 expression. Decide whether this perturbation leads to a significant alteration in PRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10848
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCT2 is associated with a significant change in BRCA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCT2 is associated with a significant change in BRCA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5715
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLE is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLE is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36345
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLE2 and examine the expression of CERT1. Does perturbing POLE2 lead to a significant change in CERT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLE2 and examine the expression of CERT1. Does perturbing POLE2 lead to a significant change in CERT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36381
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS5 is perturbed and the expression of MT-CO1 is measured. Determine whether MT-CO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS5 is perturbed and the expression of MT-CO1 is measured. Determine whether MT-CO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28816
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PIAS1 is perturbed and DMKN expression is quantified. Does this perturbation result in a significant change in DMKN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PIAS1 is perturbed and DMKN expression is quantified. Does this perturbation result in a significant change in DMKN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35532
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPL26L1 and monitor LXN expression. Decide whether this perturbation leads to a significant alteration in LXN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPL26L1 and monitor LXN expression. Decide whether this perturbation leads to a significant alteration in LXN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43828
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP56 is perturbed and the expression of CCL2 is measured. Does this perturbation cause a significant change in CCL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP56 is perturbed and the expression of CCL2 is measured. Does this perturbation cause a significant change in CCL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32240
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ENO1 is perturbed and the expression of ATF3 is measured. Determine whether ATF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ENO1 is perturbed and the expression of ATF3 is measured. Determine whether ATF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15346
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RRS1 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RRS1 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46173
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELOB is perturbed and the expression of TMEM14C is measured. Determine whether TMEM14C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELOB is perturbed and the expression of TMEM14C is measured. Determine whether TMEM14C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14996
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RIOK1 and then measure expression of FAM120C. Does this perturbation cause a significant change in FAM120C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RIOK1 and then measure expression of FAM120C. Does this perturbation cause a significant change in FAM120C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42454
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NAPA and monitor MCPH1 expression. Decide whether this perturbation leads to a significant alteration in MCPH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NAPA and monitor MCPH1 expression. Decide whether this perturbation leads to a significant alteration in MCPH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29848
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS27A is perturbed and the expression of DTL is measured. Determine whether DTL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS27A is perturbed and the expression of DTL is measured. Determine whether DTL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45536
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of HSD17B12. Does perturbing HSD17B12 lead to a significant change in HSD17B12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of HSD17B12. Does perturbing HSD17B12 lead to a significant change in HSD17B12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20701
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ANKRD11 and then measure expression of ANKRD11. Does this perturbation cause a significant change in ANKRD11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ANKRD11 and then measure expression of ANKRD11. Does this perturbation cause a significant change in ANKRD11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1504
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP15 and examine the expression of DLGAP5. Does perturbing UTP15 lead to a significant change in DLGAP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP15 and examine the expression of DLGAP5. Does perturbing UTP15 lead to a significant change in DLGAP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58511
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RNF113A is perturbed and the expression of RMI2 is measured. Does this perturbation cause a significant change in RMI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RNF113A is perturbed and the expression of RMI2 is measured. Does this perturbation cause a significant change in RMI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42600
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL49 is associated with a significant change in IFNAR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL49 is associated with a significant change in IFNAR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27945
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GON4L is perturbed and GON4L expression is observed. Does this perturbation lead to a significant difference in GON4L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GON4L is perturbed and GON4L expression is observed. Does this perturbation lead to a significant difference in GON4L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18353
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UPF3A is perturbed and SMYD3 expression is quantified. Does this perturbation result in a significant change in SMYD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UPF3A is perturbed and SMYD3 expression is quantified. Does this perturbation result in a significant change in SMYD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57842
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TONSL, does the expression profile of MAD2L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TONSL, does the expression profile of MAD2L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55037
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TADA2A and monitor RPL22L1 expression. Decide whether this perturbation leads to a significant alteration in RPL22L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TADA2A and monitor RPL22L1 expression. Decide whether this perturbation leads to a significant alteration in RPL22L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52448
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDX51 is perturbed and ZBTB25 expression is observed. Does this perturbation lead to a significant difference in ZBTB25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDX51 is perturbed and ZBTB25 expression is observed. Does this perturbation lead to a significant difference in ZBTB25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11603
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRPG is perturbed and SNRPG expression is observed. Does this perturbation lead to a significant difference in SNRPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRPG is perturbed and SNRPG expression is observed. Does this perturbation lead to a significant difference in SNRPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50223
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LAMTOR4 is perturbed and the expression of GPNMB is measured. Determine whether GPNMB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LAMTOR4 is perturbed and the expression of GPNMB is measured. Determine whether GPNMB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23666
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCDC6 is perturbed and CCDC6 expression is measured. Determine whether CCDC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCDC6 is perturbed and CCDC6 expression is measured. Determine whether CCDC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5319
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAMM41 is associated with a significant change in TGFB1I1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAMM41 is associated with a significant change in TGFB1I1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52905
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAP1 is associated with a significant change in RAB38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAP1 is associated with a significant change in RAB38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3305
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CENPA, does the expression profile of CENPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CENPA, does the expression profile of CENPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6697
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HUS1, does the expression profile of KIF3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HUS1, does the expression profile of KIF3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21047
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSME1 is perturbed and MSN expression is measured. Determine whether MSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSME1 is perturbed and MSN expression is measured. Determine whether MSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40049
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UNC45A is associated with a significant change in HDDC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UNC45A is associated with a significant change in HDDC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57725
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL11 is perturbed and MRPL11 expression is quantified. Does this perturbation result in a significant change in MRPL11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL11 is perturbed and MRPL11 expression is quantified. Does this perturbation result in a significant change in MRPL11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26972
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNL3L is perturbed and ZWILCH expression is observed. Does this perturbation lead to a significant difference in ZWILCH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNL3L is perturbed and ZWILCH expression is observed. Does this perturbation lead to a significant difference in ZWILCH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18223
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HTATSF1 is perturbed and ZNF160 expression is quantified. Does this perturbation result in a significant change in ZNF160 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HTATSF1 is perturbed and ZNF160 expression is quantified. Does this perturbation result in a significant change in ZNF160 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21022
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMA3 is associated with a significant change in TTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMA3 is associated with a significant change in TTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39165
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUVBL2 is perturbed and KIF15 expression is measured. Determine whether KIF15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUVBL2 is perturbed and KIF15 expression is measured. Determine whether KIF15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46459
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBX1 is perturbed and SUGCT expression is observed. Does this perturbation lead to a significant difference in SUGCT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBX1 is perturbed and SUGCT expression is observed. Does this perturbation lead to a significant difference in SUGCT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41953
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SH3KBP1 is perturbed and AXIN1 expression is measured. Determine whether AXIN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SH3KBP1 is perturbed and AXIN1 expression is measured. Determine whether AXIN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48239
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPMT1 is perturbed and the expression of UROD is measured. Determine whether UROD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPMT1 is perturbed and the expression of UROD is measured. Determine whether UROD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40406
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb VPS35 and monitor VPS35 expression. Decide whether this perturbation leads to a significant alteration in VPS35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb VPS35 and monitor VPS35 expression. Decide whether this perturbation leads to a significant alteration in VPS35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59138
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CPSF3 is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CPSF3 is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9622
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, THRAP3 is perturbed and BCLAF1 expression is quantified. Does this perturbation result in a significant change in BCLAF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, THRAP3 is perturbed and BCLAF1 expression is quantified. Does this perturbation result in a significant change in BCLAF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54042
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARFRP1 is perturbed and the expression of RAB18 is measured. Does this perturbation cause a significant change in RAB18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARFRP1 is perturbed and the expression of RAB18 is measured. Does this perturbation cause a significant change in RAB18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1810
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4E is perturbed and the expression of GAS5 is measured. Does this perturbation cause a significant change in GAS5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4E is perturbed and the expression of GAS5 is measured. Does this perturbation cause a significant change in GAS5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14720
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TFAM is perturbed and MT-ND6 expression is quantified. Does this perturbation result in a significant change in MT-ND6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TFAM is perturbed and MT-ND6 expression is quantified. Does this perturbation result in a significant change in MT-ND6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53572
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GRSF1 is perturbed and GRSF1 expression is quantified. Does this perturbation result in a significant change in GRSF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GRSF1 is perturbed and GRSF1 expression is quantified. Does this perturbation result in a significant change in GRSF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18632
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHPS is perturbed and NUPR1 expression is quantified. Does this perturbation result in a significant change in NUPR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHPS is perturbed and NUPR1 expression is quantified. Does this perturbation result in a significant change in NUPR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12012
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THG1L is perturbed and THG1L expression is measured. Determine whether THG1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THG1L is perturbed and THG1L expression is measured. Determine whether THG1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53829
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCAF1 is perturbed and H2AFY expression is observed. Does this perturbation lead to a significant difference in H2AFY expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCAF1 is perturbed and H2AFY expression is observed. Does this perturbation lead to a significant difference in H2AFY expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46943
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS2 is perturbed and the expression of AARS2 is measured. Determine whether AARS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS2 is perturbed and the expression of AARS2 is measured. Determine whether AARS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":126
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNTTIP2 is perturbed and NDC80 expression is quantified. Does this perturbation result in a significant change in NDC80 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNTTIP2 is perturbed and NDC80 expression is quantified. Does this perturbation result in a significant change in NDC80 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12822
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNRPF and monitor POLE2 expression. Decide whether this perturbation leads to a significant alteration in POLE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNRPF and monitor POLE2 expression. Decide whether this perturbation leads to a significant alteration in POLE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50198
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAE1 is perturbed and ZIM3 expression is observed. Does this perturbation lead to a significant difference in ZIM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAE1 is perturbed and ZIM3 expression is observed. Does this perturbation lead to a significant difference in ZIM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46523
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TFB1M and examine the expression of MT-CO1. Does perturbing TFB1M lead to a significant change in MT-CO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TFB1M and examine the expression of MT-CO1. Does perturbing TFB1M lead to a significant change in MT-CO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53591
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED16 is perturbed and the expression of SOX11 is measured. Determine whether SOX11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED16 is perturbed and the expression of SOX11 is measured. Determine whether SOX11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25516
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BANP, does the expression profile of BUB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BANP, does the expression profile of BUB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3277
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS13 and examine the expression of CDKN1A. Does perturbing RPS13 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS13 and examine the expression of CDKN1A. Does perturbing RPS13 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45051
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SHQ1, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SHQ1, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48327
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL18A is perturbed and WDR20 expression is quantified. Does this perturbation result in a significant change in WDR20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL18A is perturbed and WDR20 expression is quantified. Does this perturbation result in a significant change in WDR20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43612
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in GET3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in GET3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17645
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATXN10 is associated with a significant change in Z95331.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATXN10 is associated with a significant change in Z95331.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3135
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNHIT3 is associated with a significant change in MKI67 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNHIT3 is associated with a significant change in MKI67 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61875
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GTF3C1 and monitor EXO1 expression. Decide whether this perturbation leads to a significant alteration in EXO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GTF3C1 and monitor EXO1 expression. Decide whether this perturbation leads to a significant alteration in EXO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19128
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPS2, does the expression profile of STIL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPS2, does the expression profile of STIL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8857
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of PWWP3A. Does perturbing TTI2 lead to a significant change in PWWP3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of PWWP3A. Does perturbing TTI2 lead to a significant change in PWWP3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56281
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA8 and then measure expression of SUGCT. Does this perturbation cause a significant change in SUGCT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA8 and then measure expression of SUGCT. Does this perturbation cause a significant change in SUGCT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30594
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HERC1, does the expression profile of HERC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HERC1, does the expression profile of HERC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19907
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS7, does the expression profile of NEK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS7, does the expression profile of NEK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45757
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CYFIP1 is associated with a significant change in SEC23B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CYFIP1 is associated with a significant change in SEC23B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10555
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MED11 and monitor HIST1H1B expression. Decide whether this perturbation leads to a significant alteration in HIST1H1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MED11 and monitor HIST1H1B expression. Decide whether this perturbation leads to a significant alteration in HIST1H1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25458
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NSMCE1 is perturbed and IPO13 expression is observed. Does this perturbation lead to a significant difference in IPO13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NSMCE1 is perturbed and IPO13 expression is observed. Does this perturbation lead to a significant difference in IPO13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32593
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DR1 is perturbed and CMTR1 expression is quantified. Does this perturbation result in a significant change in CMTR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DR1 is perturbed and CMTR1 expression is quantified. Does this perturbation result in a significant change in CMTR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13122
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AURKA is perturbed and the expression of ERCC6L is measured. Does this perturbation cause a significant change in ERCC6L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AURKA is perturbed and the expression of ERCC6L is measured. Does this perturbation cause a significant change in ERCC6L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3170
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRCC1 is associated with a significant change in XRCC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRCC1 is associated with a significant change in XRCC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60445
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFA8, does the expression profile of CTSK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFA8, does the expression profile of CTSK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30587
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UHRF1 is perturbed and MYL9 expression is observed. Does this perturbation lead to a significant difference in MYL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UHRF1 is perturbed and MYL9 expression is observed. Does this perturbation lead to a significant difference in MYL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57683
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUDCD3 is perturbed and the expression of PCLAF is measured. Does this perturbation cause a significant change in PCLAF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUDCD3 is perturbed and the expression of PCLAF is measured. Does this perturbation cause a significant change in PCLAF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32840
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2L3 and examine the expression of LXN. Does perturbing UBE2L3 lead to a significant change in LXN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2L3 and examine the expression of LXN. Does perturbing UBE2L3 lead to a significant change in LXN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57291
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF3J and monitor EIF3J expression. Decide whether this perturbation leads to a significant alteration in EIF3J expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF3J and monitor EIF3J expression. Decide whether this perturbation leads to a significant alteration in EIF3J expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14528
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AFG3L2 is associated with a significant change in NUPR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AFG3L2 is associated with a significant change in NUPR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":915
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC1 and then measure expression of RRM2. Does this perturbation cause a significant change in RRM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC1 and then measure expression of RRM2. Does this perturbation cause a significant change in RRM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15984
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF4A and examine the expression of PRXL2A. Does perturbing KIF4A lead to a significant change in PRXL2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF4A and examine the expression of PRXL2A. Does perturbing KIF4A lead to a significant change in PRXL2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23161
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NISCH and examine the expression of NISCH. Does perturbing NISCH lead to a significant change in NISCH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NISCH and examine the expression of NISCH. Does perturbing NISCH lead to a significant change in NISCH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31541
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPS5 is perturbed and the expression of POGLUT3 is measured. Determine whether POGLUT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPS5 is perturbed and the expression of POGLUT3 is measured. Determine whether POGLUT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8946
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, THRAP3 is perturbed and the expression of BCLAF1 is measured. Does this perturbation cause a significant change in BCLAF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, THRAP3 is perturbed and the expression of BCLAF1 is measured. Does this perturbation cause a significant change in BCLAF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54040
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NUP107 is perturbed and MCM3 expression is quantified. Does this perturbation result in a significant change in MCM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NUP107 is perturbed and MCM3 expression is quantified. Does this perturbation result in a significant change in MCM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33002
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRPF4B is perturbed and PAQR4 expression is observed. Does this perturbation lead to a significant difference in PAQR4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRPF4B is perturbed and PAQR4 expression is observed. Does this perturbation lead to a significant difference in PAQR4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38923
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGK1, does the expression profile of PGK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGK1, does the expression profile of PGK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35227
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of HYOU1. Does perturbing HYOU1 lead to a significant change in HYOU1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of HYOU1. Does perturbing HYOU1 lead to a significant change in HYOU1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21111
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RFC1 is associated with a significant change in RFC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RFC1 is associated with a significant change in RFC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42155
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRTO4 is associated with a significant change in DNA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRTO4 is associated with a significant change in DNA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28945
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP58 and then measure expression of WDR76. Does this perturbation cause a significant change in WDR76 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP58 and then measure expression of WDR76. Does this perturbation cause a significant change in WDR76 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32274
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP1R8 and then measure expression of PPP1R8. Does this perturbation cause a significant change in PPP1R8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP1R8 and then measure expression of PPP1R8. Does this perturbation cause a significant change in PPP1R8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37964
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS3 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS3 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45613
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLRX3 is perturbed and the expression of STMP1 is measured. Determine whether STMP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLRX3 is perturbed and the expression of STMP1 is measured. Determine whether STMP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18046
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3C5 and then measure expression of GMNN. Does this perturbation cause a significant change in GMNN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3C5 and then measure expression of GMNN. Does this perturbation cause a significant change in GMNN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19254
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HIST2H2AC is perturbed and the expression of MBIP is measured. Does this perturbation cause a significant change in MBIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HIST2H2AC is perturbed and the expression of MBIP is measured. Does this perturbation cause a significant change in MBIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20040
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UQCRQ is perturbed and UQCRQ expression is observed. Does this perturbation lead to a significant difference in UQCRQ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UQCRQ is perturbed and UQCRQ expression is observed. Does this perturbation lead to a significant difference in UQCRQ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58023
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GEMIN7 and then measure expression of UBA6. Does this perturbation cause a significant change in UBA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GEMIN7 and then measure expression of UBA6. Does this perturbation cause a significant change in UBA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17564
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60562
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MLLT6 is perturbed and the expression of DNAJC21 is measured. Determine whether DNAJC21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MLLT6 is perturbed and the expression of DNAJC21 is measured. Determine whether DNAJC21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26526
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLR1C is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLR1C is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36529
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC25A3 is perturbed and the expression of PGBD1 is measured. Determine whether PGBD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC25A3 is perturbed and the expression of PGBD1 is measured. Determine whether PGBD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48656
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3H18 is perturbed and COL8A1 expression is quantified. Does this perturbation result in a significant change in COL8A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3H18 is perturbed and COL8A1 expression is quantified. Does this perturbation result in a significant change in COL8A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61112
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BRD2 and then measure expression of BRD2. Does this perturbation cause a significant change in BRD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BRD2 and then measure expression of BRD2. Does this perturbation cause a significant change in BRD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3874
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CYFIP1 is associated with a significant change in CYFIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CYFIP1 is associated with a significant change in CYFIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10535
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DRAP1 and monitor DRAP1 expression. Decide whether this perturbation leads to a significant alteration in DRAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DRAP1 and monitor DRAP1 expression. Decide whether this perturbation leads to a significant alteration in DRAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13148
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR4 is perturbed and the expression of TUT7 is measured. Does this perturbation cause a significant change in TUT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR4 is perturbed and the expression of TUT7 is measured. Does this perturbation cause a significant change in TUT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59760
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL45, does the expression profile of DMKN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL45, does the expression profile of DMKN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27887
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TUBGCP5 is perturbed and MKI67 expression is observed. Does this perturbation lead to a significant difference in MKI67 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TUBGCP5 is perturbed and MKI67 expression is observed. Does this perturbation lead to a significant difference in MKI67 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56633
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS9 is perturbed and STEAP1 expression is quantified. Does this perturbation result in a significant change in STEAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS9 is perturbed and STEAP1 expression is quantified. Does this perturbation result in a significant change in STEAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45812
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of MTURN is measured. Determine whether MTURN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of MTURN is measured. Determine whether MTURN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24686
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS11 and examine the expression of UBE2T. Does perturbing RPS11 lead to a significant change in UBE2T expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS11 and examine the expression of UBE2T. Does perturbing RPS11 lead to a significant change in UBE2T expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44971
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDC6 and monitor HMGN2 expression. Decide whether this perturbation leads to a significant alteration in HMGN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDC6 and monitor HMGN2 expression. Decide whether this perturbation leads to a significant alteration in HMGN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6328
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NUP153 and monitor MCM3 expression. Decide whether this perturbation leads to a significant alteration in MCM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NUP153 and monitor MCM3 expression. Decide whether this perturbation leads to a significant alteration in MCM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33088
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and DNAJC19 expression is observed. Does this perturbation lead to a significant difference in DNAJC19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and DNAJC19 expression is observed. Does this perturbation lead to a significant difference in DNAJC19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12603
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IFITM3 and then measure expression of IFITM3. Does this perturbation cause a significant change in IFITM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IFITM3 and then measure expression of IFITM3. Does this perturbation cause a significant change in IFITM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21244
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNL3L and then measure expression of EMP2. Does this perturbation cause a significant change in EMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNL3L and then measure expression of EMP2. Does this perturbation cause a significant change in EMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18234
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSCB, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSCB, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20647
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUDT15 is associated with a significant change in NUDT15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUDT15 is associated with a significant change in NUDT15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32855
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2D3 is perturbed and LRFN4 expression is quantified. Does this perturbation result in a significant change in LRFN4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2D3 is perturbed and LRFN4 expression is quantified. Does this perturbation result in a significant change in LRFN4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57192
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPL27 and monitor PCLAF expression. Decide whether this perturbation leads to a significant alteration in PCLAF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPL27 and monitor PCLAF expression. Decide whether this perturbation leads to a significant alteration in PCLAF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43838
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS2 is perturbed and the expression of NME3 is measured. Does this perturbation cause a significant change in NME3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS2 is perturbed and the expression of NME3 is measured. Does this perturbation cause a significant change in NME3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46750
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EPRS is perturbed and KIFC1 expression is observed. Does this perturbation lead to a significant difference in KIFC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EPRS is perturbed and KIFC1 expression is observed. Does this perturbation lead to a significant difference in KIFC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15463
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAPC2 is perturbed and SPC25 expression is quantified. Does this perturbation result in a significant change in SPC25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAPC2 is perturbed and SPC25 expression is quantified. Does this perturbation result in a significant change in SPC25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49582
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CXXC1 and examine the expression of RPL22L1. Does perturbing CXXC1 lead to a significant change in RPL22L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CXXC1 and examine the expression of RPL22L1. Does perturbing CXXC1 lead to a significant change in RPL22L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10441
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDK2 is perturbed and the expression of CDK2 is measured. Does this perturbation cause a significant change in CDK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDK2 is perturbed and the expression of CDK2 is measured. Does this perturbation cause a significant change in CDK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6520
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBC and monitor TCF19 expression. Decide whether this perturbation leads to a significant alteration in TCF19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBC and monitor TCF19 expression. Decide whether this perturbation leads to a significant alteration in TCF19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57178
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL50 is perturbed and MT-ND3 expression is measured. Determine whether MT-ND3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL50 is perturbed and MT-ND3 expression is measured. Determine whether MT-ND3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27979
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOL8 is perturbed and the expression of MCM6 is measured. Determine whether MCM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOL8 is perturbed and the expression of MCM6 is measured. Determine whether MCM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32006
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASF1B is perturbed and R3HCC1 expression is observed. Does this perturbation lead to a significant difference in R3HCC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASF1B is perturbed and R3HCC1 expression is observed. Does this perturbation lead to a significant difference in R3HCC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2243
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SETX is perturbed and CSRP2 expression is measured. Determine whether CSRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SETX is perturbed and CSRP2 expression is measured. Determine whether CSRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47839
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NF1, does the expression profile of NF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NF1, does the expression profile of NF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31247
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA5 is associated with a significant change in DCBLD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA5 is associated with a significant change in DCBLD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57085
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SHOC2 is perturbed and IGFBP6 expression is quantified. Does this perturbation result in a significant change in IGFBP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SHOC2 is perturbed and IGFBP6 expression is quantified. Does this perturbation result in a significant change in IGFBP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48282
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ANAPC1 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ANAPC1 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1276
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COX11 is perturbed and the expression of IGFBP3 is measured. Determine whether IGFBP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COX11 is perturbed and the expression of IGFBP3 is measured. Determine whether IGFBP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9236
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLRG1 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLRG1 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35859
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RTCB is perturbed and ATF4 expression is observed. Does this perturbation lead to a significant difference in ATF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RTCB is perturbed and ATF4 expression is observed. Does this perturbation lead to a significant difference in ATF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46313
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLA2 is perturbed and the expression of MEN1 is measured. Does this perturbation cause a significant change in MEN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLA2 is perturbed and the expression of MEN1 is measured. Does this perturbation cause a significant change in MEN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36230
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHAF1A is perturbed and the expression of SFR1 is measured. Does this perturbation cause a significant change in SFR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHAF1A is perturbed and the expression of SFR1 is measured. Does this perturbation cause a significant change in SFR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7160
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC4 is perturbed and RAD51 expression is measured. Determine whether RAD51 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC4 is perturbed and RAD51 expression is measured. Determine whether RAD51 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55579
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BTF3L4 is associated with a significant change in TXNDC12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BTF3L4 is associated with a significant change in TXNDC12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4155
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEP152 is perturbed and CEP152 expression is measured. Determine whether CEP152 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEP152 is perturbed and CEP152 expression is measured. Determine whether CEP152 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6999
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM19 and examine the expression of CCNA2. Does perturbing RBM19 lead to a significant change in CCNA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM19 and examine the expression of CCNA2. Does perturbing RBM19 lead to a significant change in CCNA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41581
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PCBP2 is perturbed and JPT2 expression is observed. Does this perturbation lead to a significant difference in JPT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PCBP2 is perturbed and JPT2 expression is observed. Does this perturbation lead to a significant difference in JPT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34273
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PNPT1 is perturbed and MT-CO2 expression is measured. Determine whether MT-CO2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PNPT1 is perturbed and MT-CO2 expression is measured. Determine whether MT-CO2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36109
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MPG is perturbed and DSCC1 expression is measured. Determine whether DSCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MPG is perturbed and DSCC1 expression is measured. Determine whether DSCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26819
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RGP1 and examine the expression of LETM2. Does perturbing RGP1 lead to a significant change in LETM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RGP1 and examine the expression of LETM2. Does perturbing RGP1 lead to a significant change in LETM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42381
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHEK1 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHEK1 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7366
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL3 and examine the expression of MRPL3. Does perturbing MRPL3 lead to a significant change in MRPL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL3 and examine the expression of MRPL3. Does perturbing MRPL3 lead to a significant change in MRPL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27451
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1A is perturbed and ASF1B expression is measured. Determine whether ASF1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1A is perturbed and ASF1B expression is measured. Determine whether ASF1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7149
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2E and examine the expression of POLR2E. Does perturbing POLR2E lead to a significant change in POLR2E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2E and examine the expression of POLR2E. Does perturbing POLR2E lead to a significant change in POLR2E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36721
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL27, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL27, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43837
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of ZIM3. Does this perturbation cause a significant change in ZIM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of ZIM3. Does this perturbation cause a significant change in ZIM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47794
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOSC4 is perturbed and the expression of SGO1 is measured. Determine whether SGO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOSC4 is perturbed and the expression of SGO1 is measured. Determine whether SGO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16096
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NUP133 and monitor SELENOM expression. Decide whether this perturbation leads to a significant alteration in SELENOM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NUP133 and monitor SELENOM expression. Decide whether this perturbation leads to a significant alteration in SELENOM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33048
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NR2C2AP and then measure expression of MCM2. Does this perturbation cause a significant change in MCM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NR2C2AP and then measure expression of MCM2. Does this perturbation cause a significant change in MCM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32414
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUD13 and then measure expression of PITRM1. Does this perturbation cause a significant change in PITRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUD13 and then measure expression of PITRM1. Does this perturbation cause a significant change in PITRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4264
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDPK1 is perturbed and LOXL2 expression is quantified. Does this perturbation result in a significant change in LOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDPK1 is perturbed and LOXL2 expression is quantified. Does this perturbation result in a significant change in LOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34702
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEN1 is perturbed and the expression of PLOD1 is measured. Does this perturbation cause a significant change in PLOD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEN1 is perturbed and the expression of PLOD1 is measured. Does this perturbation cause a significant change in PLOD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25890
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRELID1, does the expression profile of KIFC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRELID1, does the expression profile of KIFC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38397
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VBP1 is associated with a significant change in TAGLN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VBP1 is associated with a significant change in TAGLN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58825
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEP97 is associated with a significant change in STARD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEP97 is associated with a significant change in STARD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7075
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of KDELR3 is measured. Determine whether KDELR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of KDELR3 is measured. Determine whether KDELR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54596
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GRPEL1 is associated with a significant change in GRPEL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GRPEL1 is associated with a significant change in GRPEL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18625
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPEN and examine the expression of XIST. Does perturbing SPEN lead to a significant change in XIST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPEN and examine the expression of XIST. Does perturbing SPEN lead to a significant change in XIST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50781
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1E1 is perturbed and the expression of ATP6V1E1 is measured. Does this perturbation cause a significant change in ATP6V1E1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1E1 is perturbed and the expression of ATP6V1E1 is measured. Does this perturbation cause a significant change in ATP6V1E1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2980
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EBNA1BP2 and then measure expression of MND1. Does this perturbation cause a significant change in MND1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EBNA1BP2 and then measure expression of MND1. Does this perturbation cause a significant change in MND1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13604
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RCC1 and monitor MCM4 expression. Decide whether this perturbation leads to a significant alteration in MCM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RCC1 and monitor MCM4 expression. Decide whether this perturbation leads to a significant alteration in MCM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41988
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR54 is perturbed and PGLS expression is quantified. Does this perturbation result in a significant change in PGLS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR54 is perturbed and PGLS expression is quantified. Does this perturbation result in a significant change in PGLS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59922
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNMT1 is perturbed and the expression of COL1A1 is measured. Determine whether COL1A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNMT1 is perturbed and the expression of COL1A1 is measured. Determine whether COL1A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12786
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTR8, does the expression profile of EXOSC8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTR8, does the expression profile of EXOSC8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":757
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRSF6 and monitor SRSF6 expression. Decide whether this perturbation leads to a significant alteration in SRSF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRSF6 and monitor SRSF6 expression. Decide whether this perturbation leads to a significant alteration in SRSF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51518
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMG5 and then measure expression of EPB41L4A-AS1. Does this perturbation cause a significant change in EPB41L4A-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMG5 and then measure expression of EPB41L4A-AS1. Does this perturbation cause a significant change in EPB41L4A-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49304
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOD2 is associated with a significant change in PLAAT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOD2 is associated with a significant change in PLAAT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50425
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LTV1 is perturbed and the expression of PHF5A is measured. Determine whether PHF5A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LTV1 is perturbed and the expression of PHF5A is measured. Determine whether PHF5A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24446
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACTR1B is perturbed and the expression of PON2 is measured. Does this perturbation cause a significant change in PON2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACTR1B is perturbed and the expression of PON2 is measured. Does this perturbation cause a significant change in PON2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":630
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISG20L2 is perturbed and the expression of UHRF1 is measured. Determine whether UHRF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISG20L2 is perturbed and the expression of UHRF1 is measured. Determine whether UHRF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22346
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHCHD1 is associated with a significant change in F8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHCHD1 is associated with a significant change in F8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7225
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMG4 is perturbed and RGP1 expression is observed. Does this perturbation lead to a significant difference in RGP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMG4 is perturbed and RGP1 expression is observed. Does this perturbation lead to a significant difference in RGP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40193
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COG4 is associated with a significant change in LIMD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COG4 is associated with a significant change in LIMD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8595
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RFC2 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RFC2 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42195
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR33 and then measure expression of HIST2H2AC. Does this perturbation cause a significant change in HIST2H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR33 and then measure expression of HIST2H2AC. Does this perturbation cause a significant change in HIST2H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59704
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED6 and then measure expression of SPC24. Does this perturbation cause a significant change in SPC24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED6 and then measure expression of SPC24. Does this perturbation cause a significant change in SPC24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25774
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CXXC1 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CXXC1 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10463
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PNN is perturbed and the expression of PNN is measured. Determine whether PNN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PNN is perturbed and the expression of PNN is measured. Determine whether PNN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36036
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPR is perturbed and the expression of EHD1 is measured. Determine whether EHD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPR is perturbed and the expression of EHD1 is measured. Determine whether EHD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20566
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FAM207A is perturbed and EFCAB11 expression is quantified. Does this perturbation result in a significant change in EFCAB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FAM207A is perturbed and EFCAB11 expression is quantified. Does this perturbation result in a significant change in EFCAB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16372
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC5 is perturbed and POLE2 expression is measured. Determine whether POLE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC5 is perturbed and POLE2 expression is measured. Determine whether POLE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53959
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PAM16 and examine the expression of TGM2. Does perturbing PAM16 lead to a significant change in TGM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PAM16 and examine the expression of TGM2. Does perturbing PAM16 lead to a significant change in TGM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34151
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3L, does the expression profile of EIF3L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3L, does the expression profile of EIF3L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14557
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HCFC1 is perturbed and the expression of HDHD5 is measured. Does this perturbation cause a significant change in HDHD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HCFC1 is perturbed and the expression of HDHD5 is measured. Does this perturbation cause a significant change in HDHD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19750
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL32 is associated with a significant change in MT-ND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL32 is associated with a significant change in MT-ND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27505
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHMP2A is perturbed and WDR34 expression is measured. Determine whether WDR34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHMP2A is perturbed and WDR34 expression is measured. Determine whether WDR34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7459
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSFM is perturbed and MT-ND2 expression is observed. Does this perturbation lead to a significant difference in MT-ND2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSFM is perturbed and MT-ND2 expression is observed. Does this perturbation lead to a significant difference in MT-ND2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56033
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMG3 and then measure expression of TGM2. Does this perturbation cause a significant change in TGM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMG3 and then measure expression of TGM2. Does this perturbation cause a significant change in TGM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40144
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR70 is associated with a significant change in PRKDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR70 is associated with a significant change in PRKDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60015
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT6A and examine the expression of CCT6A. Does perturbing CCT6A lead to a significant change in CCT6A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT6A and examine the expression of CCT6A. Does perturbing CCT6A lead to a significant change in CCT6A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5821
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL24 is associated with a significant change in BIRC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL24 is associated with a significant change in BIRC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43765
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HMGB1 is perturbed and BCL2L1 expression is observed. Does this perturbation lead to a significant difference in BCL2L1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HMGB1 is perturbed and BCL2L1 expression is observed. Does this perturbation lead to a significant difference in BCL2L1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20203
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DBR1 is perturbed and DDIT3 expression is observed. Does this perturbation lead to a significant difference in DDIT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DBR1 is perturbed and DDIT3 expression is observed. Does this perturbation lead to a significant difference in DDIT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10763
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EPRS is perturbed and EPRS expression is observed. Does this perturbation lead to a significant difference in EPRS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EPRS is perturbed and EPRS expression is observed. Does this perturbation lead to a significant difference in EPRS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15473
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS2 and then measure expression of MT-ND2. Does this perturbation cause a significant change in MT-ND2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS2 and then measure expression of MT-ND2. Does this perturbation cause a significant change in MT-ND2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":144
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LAMTOR3 is perturbed and the expression of PRDX1 is measured. Does this perturbation cause a significant change in PRDX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LAMTOR3 is perturbed and the expression of PRDX1 is measured. Does this perturbation cause a significant change in PRDX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23620
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PYURF is perturbed and USP13 expression is quantified. Does this perturbation result in a significant change in USP13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PYURF is perturbed and USP13 expression is quantified. Does this perturbation result in a significant change in USP13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40652
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and PLA2G4A expression is quantified. Does this perturbation result in a significant change in PLA2G4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and PLA2G4A expression is quantified. Does this perturbation result in a significant change in PLA2G4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48742
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PGD is perturbed and KRT81 expression is measured. Determine whether KRT81 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PGD is perturbed and KRT81 expression is measured. Determine whether KRT81 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35209
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TEFM, does the expression profile of KRT18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TEFM, does the expression profile of KRT18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53377
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ESYT1 and examine the expression of RPL41. Does perturbing ESYT1 lead to a significant change in RPL41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ESYT1 and examine the expression of RPL41. Does perturbing ESYT1 lead to a significant change in RPL41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15631
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MT2A and examine the expression of MT2A. Does perturbing MT2A lead to a significant change in MT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MT2A and examine the expression of MT2A. Does perturbing MT2A lead to a significant change in MT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29041
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HAUS4 is perturbed and the expression of TAX1BP3 is measured. Does this perturbation cause a significant change in TAX1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HAUS4 is perturbed and the expression of TAX1BP3 is measured. Does this perturbation cause a significant change in TAX1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19640
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NSF and examine the expression of YIF1A. Does perturbing NSF lead to a significant change in YIF1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NSF and examine the expression of YIF1A. Does perturbing NSF lead to a significant change in YIF1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32531
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRAPPC1 is perturbed and KDELR3 expression is quantified. Does this perturbation result in a significant change in KDELR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRAPPC1 is perturbed and KDELR3 expression is quantified. Does this perturbation result in a significant change in KDELR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55482
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf25 is perturbed and FBXL4 expression is quantified. Does this perturbation result in a significant change in FBXL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf25 is perturbed and FBXL4 expression is quantified. Does this perturbation result in a significant change in FBXL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4432
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAP1, does the expression profile of CAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAP1, does the expression profile of CAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4897
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS72 is perturbed and the expression of MAGI2-AS3 is measured. Determine whether MAGI2-AS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS72 is perturbed and the expression of MAGI2-AS3 is measured. Determine whether MAGI2-AS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59286
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COA5 is perturbed and the expression of UNC50 is measured. Does this perturbation cause a significant change in UNC50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COA5 is perturbed and the expression of UNC50 is measured. Does this perturbation cause a significant change in UNC50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8450
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM2, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM2, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25107
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FBXO42 is perturbed and HCFC1R1 expression is quantified. Does this perturbation result in a significant change in HCFC1R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FBXO42 is perturbed and HCFC1R1 expression is quantified. Does this perturbation result in a significant change in HCFC1R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16722
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of RRM1. Does this perturbation cause a significant change in RRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of RRM1. Does this perturbation cause a significant change in RRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46714
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METTL3 is perturbed and PLEKHO1 expression is quantified. Does this perturbation result in a significant change in PLEKHO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METTL3 is perturbed and PLEKHO1 expression is quantified. Does this perturbation result in a significant change in PLEKHO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26192
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SF3B2, does the expression profile of STK26 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SF3B2, does the expression profile of STK26 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48027
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPL26 and monitor PCLAF expression. Decide whether this perturbation leads to a significant alteration in PCLAF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPL26 and monitor PCLAF expression. Decide whether this perturbation leads to a significant alteration in PCLAF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43788
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRNP70 is perturbed and the expression of RFC5 is measured. Determine whether RFC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRNP70 is perturbed and the expression of RFC5 is measured. Determine whether RFC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49946
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VPS25 is perturbed and VPS25 expression is quantified. Does this perturbation result in a significant change in VPS25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VPS25 is perturbed and VPS25 expression is quantified. Does this perturbation result in a significant change in VPS25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59012
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TAF5 and then measure expression of KIF14. Does this perturbation cause a significant change in KIF14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TAF5 and then measure expression of KIF14. Does this perturbation cause a significant change in KIF14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52794
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBX1 is perturbed and CBX1 expression is quantified. Does this perturbation result in a significant change in CBX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBX1 is perturbed and CBX1 expression is quantified. Does this perturbation result in a significant change in CBX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5102
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR2C is perturbed and the expression of CDCA8 is measured. Does this perturbation cause a significant change in CDCA8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR2C is perturbed and the expression of CDCA8 is measured. Does this perturbation cause a significant change in CDCA8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36670
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPAG7 and examine the expression of HIRIP3. Does perturbing SPAG7 lead to a significant change in HIRIP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPAG7 and examine the expression of HIRIP3. Does perturbing SPAG7 lead to a significant change in HIRIP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50531
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNC, does the expression profile of TGM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNC, does the expression profile of TGM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5487
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS2 is associated with a significant change in ARHGAP19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS2 is associated with a significant change in ARHGAP19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21925
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC16 is associated with a significant change in MDM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC16 is associated with a significant change in MDM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6025
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPS24 and monitor MRPS24 expression. Decide whether this perturbation leads to a significant alteration in MRPS24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPS24 and monitor MRPS24 expression. Decide whether this perturbation leads to a significant alteration in MRPS24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28508
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SMUG1 and monitor FANCA expression. Decide whether this perturbation leads to a significant alteration in FANCA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SMUG1 and monitor FANCA expression. Decide whether this perturbation leads to a significant alteration in FANCA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49518
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NFRKB and examine the expression of NUDT2. Does perturbing NFRKB lead to a significant change in NUDT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NFRKB and examine the expression of NUDT2. Does perturbing NFRKB lead to a significant change in NUDT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31301
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WBP1L is associated with a significant change in NNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WBP1L is associated with a significant change in NNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59455
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DGCR8 is associated with a significant change in AC016831.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DGCR8 is associated with a significant change in AC016831.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11895
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, INTS2 is perturbed and the expression of ARHGAP19 is measured. Does this perturbation cause a significant change in ARHGAP19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, INTS2 is perturbed and the expression of ARHGAP19 is measured. Does this perturbation cause a significant change in ARHGAP19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21920
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDX56 and monitor TRIP13 expression. Decide whether this perturbation leads to a significant alteration in TRIP13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDX56 and monitor TRIP13 expression. Decide whether this perturbation leads to a significant alteration in TRIP13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11708
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL13 is perturbed and CDCA7 expression is measured. Determine whether CDCA7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL13 is perturbed and CDCA7 expression is measured. Determine whether CDCA7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43429
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GET1, does the expression profile of FLOT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GET1, does the expression profile of FLOT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17617
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KDM1A, does the expression profile of SNX6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KDM1A, does the expression profile of SNX6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22847
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KARS is perturbed and the expression of MASTL is measured. Does this perturbation cause a significant change in MASTL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KARS is perturbed and the expression of MASTL is measured. Does this perturbation cause a significant change in MASTL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22640
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBA3 is perturbed and KRT81 expression is measured. Determine whether KRT81 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBA3 is perturbed and KRT81 expression is measured. Determine whether KRT81 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57059
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5MD is associated with a significant change in ATAD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5MD is associated with a significant change in ATAD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2575
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IMPDH2 and examine the expression of OGFOD3. Does perturbing IMPDH2 lead to a significant change in OGFOD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IMPDH2 and examine the expression of OGFOD3. Does perturbing IMPDH2 lead to a significant change in OGFOD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21471
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFAB1 is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFAB1 is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30623
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPP2R1A and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPP2R1A and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38068
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KRT10 is perturbed and KRT10 expression is observed. Does this perturbation lead to a significant difference in KRT10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KRT10 is perturbed and KRT10 expression is observed. Does this perturbation lead to a significant difference in KRT10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23403
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDR25, does the expression profile of ALG9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDR25, does the expression profile of ALG9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59637
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCM10 is perturbed and SUGCT expression is measured. Determine whether SUGCT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCM10 is perturbed and SUGCT expression is measured. Determine whether SUGCT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25079
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF2F2, does the expression profile of PLIN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF2F2, does the expression profile of PLIN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18947
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35824
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VARS is perturbed and TRIB3 expression is quantified. Does this perturbation result in a significant change in TRIB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VARS is perturbed and TRIB3 expression is quantified. Does this perturbation result in a significant change in TRIB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58772
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOD1 is associated with a significant change in CENPK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOD1 is associated with a significant change in CENPK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50385
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS11 is perturbed and MRPL46 expression is quantified. Does this perturbation result in a significant change in MRPL46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS11 is perturbed and MRPL46 expression is quantified. Does this perturbation result in a significant change in MRPL46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28152
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PDPK1 and monitor LOXL2 expression. Decide whether this perturbation leads to a significant alteration in LOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDPK1 and monitor LOXL2 expression. Decide whether this perturbation leads to a significant alteration in LOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34708
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UQCRH, does the expression profile of ZNF496 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UQCRH, does the expression profile of ZNF496 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58017
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPA and examine the expression of MICALL1. Does perturbing COPA lead to a significant change in MICALL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPA and examine the expression of MICALL1. Does perturbing COPA lead to a significant change in MICALL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8701
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5F1A, does the expression profile of ATP5F1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5F1A, does the expression profile of ATP5F1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2467
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR1B, does the expression profile of MCM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR1B, does the expression profile of MCM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36507
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBX1 is perturbed and the expression of RBX1 is measured. Determine whether RBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBX1 is perturbed and the expression of RBX1 is measured. Determine whether RBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41946
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHAF1A and examine the expression of SFR1. Does perturbing CHAF1A lead to a significant change in SFR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHAF1A and examine the expression of SFR1. Does perturbing CHAF1A lead to a significant change in SFR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7161
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ECD is associated with a significant change in CENPM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ECD is associated with a significant change in CENPM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13645
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP11B is perturbed and HSBP1 expression is observed. Does this perturbation lead to a significant difference in HSBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP11B is perturbed and HSBP1 expression is observed. Does this perturbation lead to a significant difference in HSBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2393
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBCC is perturbed and C21orf58 expression is measured. Determine whether C21orf58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBCC is perturbed and C21orf58 expression is measured. Determine whether C21orf58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53139
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCNM1 and examine the expression of FAM92A. Does perturbing SCNM1 lead to a significant change in FAM92A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCNM1 and examine the expression of FAM92A. Does perturbing SCNM1 lead to a significant change in FAM92A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47051
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPIL4, does the expression profile of PPIL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPIL4, does the expression profile of PPIL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37627
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDHD1 is perturbed and CCDC152 expression is measured. Determine whether CCDC152 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDHD1 is perturbed and CCDC152 expression is measured. Determine whether CCDC152 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59509
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SUGT1 and monitor CDCA5 expression. Decide whether this perturbation leads to a significant alteration in CDCA5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SUGT1 and monitor CDCA5 expression. Decide whether this perturbation leads to a significant alteration in CDCA5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52078
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJA3 and examine the expression of MT-CO3. Does perturbing DNAJA3 lead to a significant change in MT-CO3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJA3 and examine the expression of MT-CO3. Does perturbing DNAJA3 lead to a significant change in MT-CO3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12531
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARS2 is perturbed and the expression of RMI1 is measured. Determine whether RMI1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARS2 is perturbed and the expression of RMI1 is measured. Determine whether RMI1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16456
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SF3A2 is perturbed and BBC3 expression is measured. Determine whether BBC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SF3A2 is perturbed and BBC3 expression is measured. Determine whether BBC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47929
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF4A3 and examine the expression of TARBP1. Does perturbing EIF4A3 lead to a significant change in TARBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF4A3 and examine the expression of TARBP1. Does perturbing EIF4A3 lead to a significant change in TARBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14661
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2G, does the expression profile of AGO2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2G, does the expression profile of AGO2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36797
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL2 is perturbed and the expression of MT-ND3 is measured. Does this perturbation cause a significant change in MT-ND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL2 is perturbed and the expression of MT-ND3 is measured. Does this perturbation cause a significant change in MT-ND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27230
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LARS is perturbed and the expression of LARS is measured. Determine whether LARS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LARS is perturbed and the expression of LARS is measured. Determine whether LARS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23676
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF7 is perturbed and the expression of CEP152 is measured. Does this perturbation cause a significant change in CEP152 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF7 is perturbed and the expression of CEP152 is measured. Does this perturbation cause a significant change in CEP152 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30710
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HAUS4 and then measure expression of TAX1BP3. Does this perturbation cause a significant change in TAX1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HAUS4 and then measure expression of TAX1BP3. Does this perturbation cause a significant change in TAX1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19644
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KEAP1 is perturbed and the expression of KEAP1 is measured. Does this perturbation cause a significant change in KEAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KEAP1 is perturbed and the expression of KEAP1 is measured. Does this perturbation cause a significant change in KEAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22950
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DCTN4 is perturbed and the expression of NASP is measured. Does this perturbation cause a significant change in NASP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DCTN4 is perturbed and the expression of NASP is measured. Does this perturbation cause a significant change in NASP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10900
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRPF4 and monitor STMN1 expression. Decide whether this perturbation leads to a significant alteration in STMN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRPF4 and monitor STMN1 expression. Decide whether this perturbation leads to a significant alteration in STMN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38858
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCDC59 and then measure expression of SGO1. Does this perturbation cause a significant change in SGO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCDC59 and then measure expression of SGO1. Does this perturbation cause a significant change in SGO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5284
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX11 and examine the expression of DDX11. Does perturbing DDX11 lead to a significant change in DDX11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX11 and examine the expression of DDX11. Does perturbing DDX11 lead to a significant change in DDX11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11131
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBPL1 is perturbed and MSMO1 expression is observed. Does this perturbation lead to a significant difference in MSMO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBPL1 is perturbed and MSMO1 expression is observed. Does this perturbation lead to a significant difference in MSMO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53233
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PITRM1 is perturbed and PRDX4 expression is measured. Determine whether PRDX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PITRM1 is perturbed and PRDX4 expression is measured. Determine whether PRDX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35689
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1E1 and examine the expression of MSMO1. Does perturbing ATP6V1E1 lead to a significant change in MSMO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1E1 and examine the expression of MSMO1. Does perturbing ATP6V1E1 lead to a significant change in MSMO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2991
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAPC2 and then measure expression of NUF2. Does this perturbation cause a significant change in NUF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAPC2 and then measure expression of NUF2. Does this perturbation cause a significant change in NUF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49564
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MED11 is perturbed and the expression of NCAPH is measured. Does this perturbation cause a significant change in NCAPH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MED11 is perturbed and the expression of NCAPH is measured. Does this perturbation cause a significant change in NCAPH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25460
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMB6 and examine the expression of HMOX1. Does perturbing PSMB6 lead to a significant change in HMOX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMB6 and examine the expression of HMOX1. Does perturbing PSMB6 lead to a significant change in HMOX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39441
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LSG1 is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LSG1 is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24102
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED6 is perturbed and the expression of SPC24 is measured. Determine whether SPC24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED6 is perturbed and the expression of SPC24 is measured. Determine whether SPC24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25776
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NAA20 is perturbed and GDF6 expression is measured. Determine whether GDF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NAA20 is perturbed and GDF6 expression is measured. Determine whether GDF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29539
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COMTD1 is perturbed and the expression of HNRNPA1 is measured. Determine whether HNRNPA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COMTD1 is perturbed and the expression of HNRNPA1 is measured. Determine whether HNRNPA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8676
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBBP8 and examine the expression of BCL7A. Does perturbing RBBP8 lead to a significant change in BCL7A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBBP8 and examine the expression of BCL7A. Does perturbing RBBP8 lead to a significant change in BCL7A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41481
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V0B and examine the expression of ATP6V0B. Does perturbing ATP6V0B lead to a significant change in ATP6V0B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V0B and examine the expression of ATP6V0B. Does perturbing ATP6V0B lead to a significant change in ATP6V0B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2761
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CRLS1 is perturbed and the expression of SGSM2 is measured. Does this perturbation cause a significant change in SGSM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CRLS1 is perturbed and the expression of SGSM2 is measured. Does this perturbation cause a significant change in SGSM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9760
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRCC2, does the expression profile of XRCC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRCC2, does the expression profile of XRCC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60467
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM127 is associated with a significant change in TMEM127 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM127 is associated with a significant change in TMEM127 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54605
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK1, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK1, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35817
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MPHOSPH6 is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MPHOSPH6 is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26872
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC73 is perturbed and the expression of CDKN3 is measured. Does this perturbation cause a significant change in CDKN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC73 is perturbed and the expression of CDKN3 is measured. Does this perturbation cause a significant change in CDKN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6350
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LTBP3, does the expression profile of CDKN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LTBP3, does the expression profile of CDKN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24377
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GSK3B and then measure expression of EMP3. Does this perturbation cause a significant change in EMP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GSK3B and then measure expression of EMP3. Does this perturbation cause a significant change in EMP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18694
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF2BP2 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF2BP2 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22255
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIS18BP1 is associated with a significant change in MCM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIS18BP1 is associated with a significant change in MCM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26465
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMG5 is associated with a significant change in SNHG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMG5 is associated with a significant change in SNHG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49315
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GEMIN5 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GEMIN5 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17509
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AKIRIN2 is perturbed and SOX11 expression is quantified. Does this perturbation result in a significant change in SOX11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AKIRIN2 is perturbed and SOX11 expression is quantified. Does this perturbation result in a significant change in SOX11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1072
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B5, does the expression profile of MKI67 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B5, does the expression profile of MKI67 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14197
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PYURF and monitor USP13 expression. Decide whether this perturbation leads to a significant alteration in USP13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PYURF and monitor USP13 expression. Decide whether this perturbation leads to a significant alteration in USP13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40658
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL26, does the expression profile of CDKN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL26, does the expression profile of CDKN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43797
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POGLUT3 and then measure expression of COPRS. Does this perturbation cause a significant change in COPRS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POGLUT3 and then measure expression of COPRS. Does this perturbation cause a significant change in COPRS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36144
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAP30BP is perturbed and TMSB15A expression is quantified. Does this perturbation result in a significant change in TMSB15A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAP30BP is perturbed and TMSB15A expression is quantified. Does this perturbation result in a significant change in TMSB15A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46672
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UQCRB, does the expression profile of SRGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UQCRB, does the expression profile of SRGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57887
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS17 and then measure expression of ERCC6L. Does this perturbation cause a significant change in ERCC6L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS17 and then measure expression of ERCC6L. Does this perturbation cause a significant change in ERCC6L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45174
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SKA3 is associated with a significant change in PISD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SKA3 is associated with a significant change in PISD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48435
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC16A is perturbed and SEC16A expression is quantified. Does this perturbation result in a significant change in SEC16A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC16A is perturbed and SEC16A expression is quantified. Does this perturbation result in a significant change in SEC16A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47322
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RFC3 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RFC3 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42230
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRRC2A and then measure expression of NPTN. Does this perturbation cause a significant change in NPTN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRRC2A and then measure expression of NPTN. Does this perturbation cause a significant change in NPTN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39014
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C12orf45 and examine the expression of MCM5. Does perturbing C12orf45 lead to a significant change in MCM5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C12orf45 and examine the expression of MCM5. Does perturbing C12orf45 lead to a significant change in MCM5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4351
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GABPB1 is perturbed and the expression of GABPB1 is measured. Determine whether GABPB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GABPB1 is perturbed and the expression of GABPB1 is measured. Determine whether GABPB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17226
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP9 is perturbed and GAS5 expression is observed. Does this perturbation lead to a significant difference in GAS5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP9 is perturbed and GAS5 expression is observed. Does this perturbation lead to a significant difference in GAS5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51233
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB4B is perturbed and the expression of ALDH1A3 is measured. Determine whether ALDH1A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB4B is perturbed and the expression of ALDH1A3 is measured. Determine whether ALDH1A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40806
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRRM1 is perturbed and SRRM1 expression is measured. Determine whether SRRM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRRM1 is perturbed and SRRM1 expression is measured. Determine whether SRRM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51279
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2B and then measure expression of MRPS27. Does this perturbation cause a significant change in MRPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2B and then measure expression of MRPS27. Does this perturbation cause a significant change in MRPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18814
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPH1 is perturbed and the expression of FBXO5 is measured. Does this perturbation cause a significant change in FBXO5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPH1 is perturbed and the expression of FBXO5 is measured. Does this perturbation cause a significant change in FBXO5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20990
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GEMIN5 is perturbed and GEMIN5 expression is quantified. Does this perturbation result in a significant change in GEMIN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GEMIN5 is perturbed and GEMIN5 expression is quantified. Does this perturbation result in a significant change in GEMIN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17492
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RTF1 is perturbed and PKMYT1 expression is measured. Determine whether PKMYT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RTF1 is perturbed and PKMYT1 expression is measured. Determine whether PKMYT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46329
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NSL1 is perturbed and the expression of NSL1 is measured. Does this perturbation cause a significant change in NSL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NSL1 is perturbed and the expression of NSL1 is measured. Does this perturbation cause a significant change in NSL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32550
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRIM1, does the expression profile of MCM10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRIM1, does the expression profile of MCM10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38437
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMG3 is perturbed and PSMG3 expression is measured. Determine whether PSMG3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMG3 is perturbed and PSMG3 expression is measured. Determine whether PSMG3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40159
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LETM1 is associated with a significant change in PSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LETM1 is associated with a significant change in PSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23865
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LUC7L3 is perturbed and the expression of AGTRAP is measured. Determine whether AGTRAP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LUC7L3 is perturbed and the expression of AGTRAP is measured. Determine whether AGTRAP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24456
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDX59 and monitor SIX4 expression. Decide whether this perturbation leads to a significant alteration in SIX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDX59 and monitor SIX4 expression. Decide whether this perturbation leads to a significant alteration in SIX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11748
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GPN3 and examine the expression of AFF3. Does perturbing GPN3 lead to a significant change in AFF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GPN3 and examine the expression of AFF3. Does perturbing GPN3 lead to a significant change in AFF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18501
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBE2D3, does the expression profile of ANKRD50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBE2D3, does the expression profile of ANKRD50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57207
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRNP27 is perturbed and SNRNP27 expression is observed. Does this perturbation lead to a significant difference in SNRNP27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRNP27 is perturbed and SNRNP27 expression is observed. Does this perturbation lead to a significant difference in SNRNP27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49803
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of TRIB3 is measured. Does this perturbation cause a significant change in TRIB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of TRIB3 is measured. Does this perturbation cause a significant change in TRIB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14240
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCT6A is perturbed and the expression of CCT6A is measured. Does this perturbation cause a significant change in CCT6A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCT6A is perturbed and the expression of CCT6A is measured. Does this perturbation cause a significant change in CCT6A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5820
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOSC3, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOSC3, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16077
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAPC1 and monitor IMPA2 expression. Decide whether this perturbation leads to a significant alteration in IMPA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAPC1 and monitor IMPA2 expression. Decide whether this perturbation leads to a significant alteration in IMPA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49548
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHX15 and examine the expression of RPL22L1. Does perturbing DHX15 lead to a significant change in RPL22L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHX15 and examine the expression of RPL22L1. Does perturbing DHX15 lead to a significant change in RPL22L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12031
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF720 and monitor SLC4A7 expression. Decide whether this perturbation leads to a significant alteration in SLC4A7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF720 and monitor SLC4A7 expression. Decide whether this perturbation leads to a significant alteration in SLC4A7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61738
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUS1 is perturbed and the expression of AC093673.1 is measured. Does this perturbation cause a significant change in AC093673.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUS1 is perturbed and the expression of AC093673.1 is measured. Does this perturbation cause a significant change in AC093673.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33440
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPL34 and monitor CLN6 expression. Decide whether this perturbation leads to a significant alteration in CLN6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPL34 and monitor CLN6 expression. Decide whether this perturbation leads to a significant alteration in CLN6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44078
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL18A is perturbed and the expression of NRGN is measured. Determine whether NRGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL18A is perturbed and the expression of NRGN is measured. Determine whether NRGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43596
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50682
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RFFL is perturbed and the expression of GPR107 is measured. Does this perturbation cause a significant change in GPR107 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RFFL is perturbed and the expression of GPR107 is measured. Does this perturbation cause a significant change in GPR107 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42300
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED22, does the expression profile of RRM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED22, does the expression profile of RRM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25597
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALG14, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALG14, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1197
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EWSR1 and examine the expression of EWSR1. Does perturbing EWSR1 lead to a significant change in EWSR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EWSR1 and examine the expression of EWSR1. Does perturbing EWSR1 lead to a significant change in EWSR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15721
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SDHA, does the expression profile of FASTKD5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SDHA, does the expression profile of FASTKD5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47187
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTPAP is associated with a significant change in MT-CO2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTPAP is associated with a significant change in MT-CO2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29175
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK1 is associated with a significant change in SAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK1 is associated with a significant change in SAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35815
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL18 is perturbed and MT-ND2 expression is quantified. Does this perturbation result in a significant change in MT-ND2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL18 is perturbed and MT-ND2 expression is quantified. Does this perturbation result in a significant change in MT-ND2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27172
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLRX5 is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLRX5 is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18070
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS29 is perturbed and LRR1 expression is observed. Does this perturbation lead to a significant difference in LRR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS29 is perturbed and LRR1 expression is observed. Does this perturbation lead to a significant difference in LRR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45573
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA8 is associated with a significant change in VPS13A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA8 is associated with a significant change in VPS13A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20865
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOQ is perturbed and RSU1 expression is measured. Determine whether RSU1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOQ is perturbed and RSU1 expression is measured. Determine whether RSU1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42409
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEN1 is perturbed and the expression of PLOD1 is measured. Determine whether PLOD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEN1 is perturbed and the expression of PLOD1 is measured. Determine whether PLOD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25896
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KRI1 and monitor ATAD5 expression. Decide whether this perturbation leads to a significant alteration in ATAD5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KRI1 and monitor ATAD5 expression. Decide whether this perturbation leads to a significant alteration in ATAD5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23358
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNIP1 and monitor CDCA2 expression. Decide whether this perturbation leads to a significant alteration in CDCA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNIP1 and monitor CDCA2 expression. Decide whether this perturbation leads to a significant alteration in CDCA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49718
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS41 is perturbed and BEX3 expression is measured. Determine whether BEX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS41 is perturbed and BEX3 expression is measured. Determine whether BEX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59199
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTR3 is perturbed and the expression of EMP2 is measured. Determine whether EMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTR3 is perturbed and the expression of EMP2 is measured. Determine whether EMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":716
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PHB2 is perturbed and PHB2 expression is quantified. Does this perturbation result in a significant change in PHB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PHB2 is perturbed and PHB2 expression is quantified. Does this perturbation result in a significant change in PHB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35372
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor FST expression. Decide whether this perturbation leads to a significant alteration in FST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor FST expression. Decide whether this perturbation leads to a significant alteration in FST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40438
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRD4 is associated with a significant change in ZNF580 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRD4 is associated with a significant change in ZNF580 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3905
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLU7 is perturbed and DDIT3 expression is measured. Determine whether DDIT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLU7 is perturbed and DDIT3 expression is measured. Determine whether DDIT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48939
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3I and examine the expression of EIF3I. Does perturbing EIF3I lead to a significant change in EIF3I expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3I and examine the expression of EIF3I. Does perturbing EIF3I lead to a significant change in EIF3I expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14491
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EEF1A1 is perturbed and EEFSEC expression is observed. Does this perturbation lead to a significant difference in EEFSEC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EEF1A1 is perturbed and EEFSEC expression is observed. Does this perturbation lead to a significant difference in EEFSEC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13713
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MCMBP is perturbed and the expression of H2AFX is measured. Does this perturbation cause a significant change in H2AFX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MCMBP is perturbed and the expression of H2AFX is measured. Does this perturbation cause a significant change in H2AFX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25310
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMB1 and monitor KIFC1 expression. Decide whether this perturbation leads to a significant alteration in KIFC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMB1 and monitor KIFC1 expression. Decide whether this perturbation leads to a significant alteration in KIFC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39288
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DYNLRB1 is perturbed and the expression of S100A6 is measured. Determine whether S100A6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DYNLRB1 is perturbed and the expression of S100A6 is measured. Determine whether S100A6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13506
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SKP1 and examine the expression of MUL1. Does perturbing SKP1 lead to a significant change in MUL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SKP1 and examine the expression of MUL1. Does perturbing SKP1 lead to a significant change in MUL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48461
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAPC2 is perturbed and the expression of SPC25 is measured. Determine whether SPC25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAPC2 is perturbed and the expression of SPC25 is measured. Determine whether SPC25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49586
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOC5 is associated with a significant change in IGFBP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOC5 is associated with a significant change in IGFBP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15895
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RRN3 and then measure expression of FANCM. Does this perturbation cause a significant change in FANCM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RRN3 and then measure expression of FANCM. Does this perturbation cause a significant change in FANCM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46014
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SF3A1 is perturbed and ATF3 expression is measured. Determine whether ATF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SF3A1 is perturbed and ATF3 expression is measured. Determine whether ATF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47889
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NUP43 is perturbed and GFOD1 expression is quantified. Does this perturbation result in a significant change in GFOD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NUP43 is perturbed and GFOD1 expression is quantified. Does this perturbation result in a significant change in GFOD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33242
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DOLK and examine the expression of DOLK. Does perturbing DOLK lead to a significant change in DOLK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DOLK and examine the expression of DOLK. Does perturbing DOLK lead to a significant change in DOLK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12871
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCDC115 is perturbed and the expression of CCNE2 is measured. Does this perturbation cause a significant change in CCNE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCDC115 is perturbed and the expression of CCNE2 is measured. Does this perturbation cause a significant change in CCNE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5160
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FBXO5 is perturbed and the expression of GNL3L is measured. Does this perturbation cause a significant change in GNL3L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FBXO5 is perturbed and the expression of GNL3L is measured. Does this perturbation cause a significant change in GNL3L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16760
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MED7 is perturbed and PRIM1 expression is observed. Does this perturbation lead to a significant difference in PRIM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MED7 is perturbed and PRIM1 expression is observed. Does this perturbation lead to a significant difference in PRIM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25813
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF3A and examine the expression of GTF3A. Does perturbing GTF3A lead to a significant change in GTF3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF3A and examine the expression of GTF3A. Does perturbing GTF3A lead to a significant change in GTF3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19081
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DSTYK is perturbed and MRPL17 expression is quantified. Does this perturbation result in a significant change in MRPL17 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DSTYK is perturbed and MRPL17 expression is quantified. Does this perturbation result in a significant change in MRPL17 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13262
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NELFCD and then measure expression of RPL22L1. Does this perturbation cause a significant change in RPL22L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NELFCD and then measure expression of RPL22L1. Does this perturbation cause a significant change in RPL22L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31124
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD9 and then measure expression of BTN2A2. Does this perturbation cause a significant change in BTN2A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD9 and then measure expression of BTN2A2. Does this perturbation cause a significant change in BTN2A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40004
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFB10 is perturbed and HSBP1 expression is measured. Determine whether HSBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFB10 is perturbed and HSBP1 expression is measured. Determine whether HSBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30749
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPS11 and monitor MT-ND2 expression. Decide whether this perturbation leads to a significant alteration in MT-ND2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPS11 and monitor MT-ND2 expression. Decide whether this perturbation leads to a significant alteration in MT-ND2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28168
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SKA1 is perturbed and SKA1 expression is measured. Determine whether SKA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SKA1 is perturbed and SKA1 expression is measured. Determine whether SKA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48399
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and CALR expression is observed. Does this perturbation lead to a significant difference in CALR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and CALR expression is observed. Does this perturbation lead to a significant difference in CALR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51263
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRKRIP1 and monitor FAM177A1 expression. Decide whether this perturbation leads to a significant alteration in FAM177A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRKRIP1 and monitor FAM177A1 expression. Decide whether this perturbation leads to a significant alteration in FAM177A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38558
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK9 and then measure expression of EXO1. Does this perturbation cause a significant change in EXO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK9 and then measure expression of EXO1. Does this perturbation cause a significant change in EXO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6584
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIPIN is perturbed and the expression of HMGB2 is measured. Does this perturbation cause a significant change in HMGB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIPIN is perturbed and the expression of HMGB2 is measured. Does this perturbation cause a significant change in HMGB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54370
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UNC45A is perturbed and the expression of FANCG is measured. Determine whether FANCG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UNC45A is perturbed and the expression of FANCG is measured. Determine whether FANCG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57746
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KDM5C is perturbed and the expression of HCFC1R1 is measured. Determine whether HCFC1R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KDM5C is perturbed and the expression of HCFC1R1 is measured. Determine whether HCFC1R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22896
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MVD is perturbed and the expression of TBC1D31 is measured. Determine whether TBC1D31 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MVD is perturbed and the expression of TBC1D31 is measured. Determine whether TBC1D31 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29236
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS7 is perturbed and NEK2 expression is quantified. Does this perturbation result in a significant change in NEK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS7 is perturbed and NEK2 expression is quantified. Does this perturbation result in a significant change in NEK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45752
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ISCA2 and monitor NPC2 expression. Decide whether this perturbation leads to a significant alteration in NPC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ISCA2 and monitor NPC2 expression. Decide whether this perturbation leads to a significant alteration in NPC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22268
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UPF2 is perturbed and SNHG7 expression is quantified. Does this perturbation result in a significant change in SNHG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UPF2 is perturbed and SNHG7 expression is quantified. Does this perturbation result in a significant change in SNHG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57832
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BANP and monitor BUB1 expression. Decide whether this perturbation leads to a significant alteration in BUB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BANP and monitor BUB1 expression. Decide whether this perturbation leads to a significant alteration in BUB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3278
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLEKHN1 is perturbed and MSL3 expression is measured. Determine whether MSL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLEKHN1 is perturbed and MSL3 expression is measured. Determine whether MSL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35789
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZWINT is associated with a significant change in ZMAT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZWINT is associated with a significant change in ZMAT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62065
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL23A and then measure expression of SPC24. Does this perturbation cause a significant change in SPC24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL23A and then measure expression of SPC24. Does this perturbation cause a significant change in SPC24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43724
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KAT5 is perturbed and TEAD2 expression is measured. Determine whether TEAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KAT5 is perturbed and TEAD2 expression is measured. Determine whether TEAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22679
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RMI1 is perturbed and the expression of SPATA7 is measured. Determine whether SPATA7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RMI1 is perturbed and the expression of SPATA7 is measured. Determine whether SPATA7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42516
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGBP1 is perturbed and SERPINB2 expression is quantified. Does this perturbation result in a significant change in SERPINB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGBP1 is perturbed and SERPINB2 expression is quantified. Does this perturbation result in a significant change in SERPINB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21282
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and NRGN expression is measured. Determine whether NRGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and NRGN expression is measured. Determine whether NRGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47429
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFDP1 is perturbed and the expression of TFDP1 is measured. Determine whether TFDP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFDP1 is perturbed and the expression of TFDP1 is measured. Determine whether TFDP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53656
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZW10, does the expression profile of SCD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZW10, does the expression profile of SCD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62037
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor TRIB3 expression. Decide whether this perturbation leads to a significant alteration in TRIB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor TRIB3 expression. Decide whether this perturbation leads to a significant alteration in TRIB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ANAPC4 and then measure expression of CDCA4. Does this perturbation cause a significant change in CDCA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ANAPC4 and then measure expression of CDCA4. Does this perturbation cause a significant change in CDCA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1424
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C7orf50 is perturbed and TMX4 expression is quantified. Does this perturbation result in a significant change in TMX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C7orf50 is perturbed and TMX4 expression is quantified. Does this perturbation result in a significant change in TMX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4672
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEFSEC and examine the expression of ANXA3. Does perturbing EEFSEC lead to a significant change in ANXA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEFSEC and examine the expression of ANXA3. Does perturbing EEFSEC lead to a significant change in ANXA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13831
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARMC6 and then measure expression of SUGP2. Does this perturbation cause a significant change in SUGP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARMC6 and then measure expression of SUGP2. Does this perturbation cause a significant change in SUGP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2024
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and NEDD8 expression is observed. Does this perturbation lead to a significant difference in NEDD8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and NEDD8 expression is observed. Does this perturbation lead to a significant difference in NEDD8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31033
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SACM1L, does the expression profile of SACM1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SACM1L, does the expression profile of SACM1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46477
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C4 is perturbed and PICALM expression is observed. Does this perturbation lead to a significant difference in PICALM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C4 is perturbed and PICALM expression is observed. Does this perturbation lead to a significant difference in PICALM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19203
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZRANB2 and examine the expression of PGS1. Does perturbing ZRANB2 lead to a significant change in PGS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZRANB2 and examine the expression of PGS1. Does perturbing ZRANB2 lead to a significant change in PGS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61961
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKAP5 is perturbed and CLSTN2 expression is quantified. Does this perturbation result in a significant change in CLSTN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKAP5 is perturbed and CLSTN2 expression is quantified. Does this perturbation result in a significant change in CLSTN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7802
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPN1 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPN1 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44712
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX23 is perturbed and the expression of HIST3H2A is measured. Determine whether HIST3H2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX23 is perturbed and the expression of HIST3H2A is measured. Determine whether HIST3H2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11346
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SMG9 is perturbed and the expression of SNHG19 is measured. Does this perturbation cause a significant change in SNHG19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SMG9 is perturbed and the expression of SNHG19 is measured. Does this perturbation cause a significant change in SNHG19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49410
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OGFOD1 is perturbed and the expression of RPL22L1 is measured. Determine whether RPL22L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OGFOD1 is perturbed and the expression of RPL22L1 is measured. Determine whether RPL22L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33566
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPIL4 and monitor ZMAT3 expression. Decide whether this perturbation leads to a significant alteration in ZMAT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPIL4 and monitor ZMAT3 expression. Decide whether this perturbation leads to a significant alteration in ZMAT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37648
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MALSU1 is associated with a significant change in MT-ND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MALSU1 is associated with a significant change in MT-ND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24645
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNHIT1 and monitor CLIC1 expression. Decide whether this perturbation leads to a significant alteration in CLIC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNHIT1 and monitor CLIC1 expression. Decide whether this perturbation leads to a significant alteration in CLIC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61818
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UCHL5 is perturbed and the expression of SNRNP40 is measured. Does this perturbation cause a significant change in SNRNP40 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UCHL5 is perturbed and the expression of SNRNP40 is measured. Does this perturbation cause a significant change in SNRNP40 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57590
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4E and then measure expression of EIF4E. Does this perturbation cause a significant change in EIF4E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4E and then measure expression of EIF4E. Does this perturbation cause a significant change in EIF4E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14704
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRELID3B and examine the expression of MT-CO3. Does perturbing PRELID3B lead to a significant change in MT-CO3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRELID3B and examine the expression of MT-CO3. Does perturbing PRELID3B lead to a significant change in MT-CO3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38421
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF2F2 is perturbed and the expression of BLM is measured. Determine whether BLM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF2F2 is perturbed and the expression of BLM is measured. Determine whether BLM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18956
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LIN54 and examine the expression of PDLIM2. Does perturbing LIN54 lead to a significant change in PDLIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LIN54 and examine the expression of PDLIM2. Does perturbing LIN54 lead to a significant change in PDLIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23921
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRSF6 is associated with a significant change in NEAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRSF6 is associated with a significant change in NEAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51525
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and SEC63 expression is observed. Does this perturbation lead to a significant difference in SEC63 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and SEC63 expression is observed. Does this perturbation lead to a significant difference in SEC63 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47463
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL51 is perturbed and the expression of MRPL51 is measured. Determine whether MRPL51 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL51 is perturbed and the expression of MRPL51 is measured. Determine whether MRPL51 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27996
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZWINT, does the expression profile of ZMAT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZWINT, does the expression profile of ZMAT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62067
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX1, does the expression profile of PSAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX1, does the expression profile of PSAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11097
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPH1 and then measure expression of RBM3. Does this perturbation cause a significant change in RBM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPH1 and then measure expression of RBM3. Does this perturbation cause a significant change in RBM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20434
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDIPT, does the expression profile of CAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDIPT, does the expression profile of CAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6417
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SON and then measure expression of DNAJB9. Does this perturbation cause a significant change in DNAJB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SON and then measure expression of DNAJB9. Does this perturbation cause a significant change in DNAJB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50444
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR3B is perturbed and the expression of COQ3 is measured. Determine whether COQ3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR3B is perturbed and the expression of COQ3 is measured. Determine whether COQ3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36996
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SUPT20H and examine the expression of CD9. Does perturbing SUPT20H lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SUPT20H and examine the expression of CD9. Does perturbing SUPT20H lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52141
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ADNP2, does the expression profile of MTF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ADNP2, does the expression profile of MTF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":837
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPUSD4 is perturbed and the expression of MT-ND2 is measured. Determine whether MT-ND2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPUSD4 is perturbed and the expression of MT-ND2 is measured. Determine whether MT-ND2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45916
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL4 is associated with a significant change in SUGCT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL4 is associated with a significant change in SUGCT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44375
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARL4D is associated with a significant change in CHRDL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARL4D is associated with a significant change in CHRDL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1955
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX19A is perturbed and FANCA expression is measured. Determine whether FANCA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX19A is perturbed and FANCA expression is measured. Determine whether FANCA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11249
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COQ5 is perturbed and the expression of CRYAB is measured. Does this perturbation cause a significant change in CRYAB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COQ5 is perturbed and the expression of CRYAB is measured. Does this perturbation cause a significant change in CRYAB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9130
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMB2, does the expression profile of HMOX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMB2, does the expression profile of HMOX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39327
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOP56, does the expression profile of NOP56 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOP56, does the expression profile of NOP56 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32227
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RARS2 is associated with a significant change in RARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RARS2 is associated with a significant change in RARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41345
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL43, does the expression profile of MRPL43 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL43, does the expression profile of MRPL43 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27817
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMC6 is perturbed and CCNA2 expression is quantified. Does this perturbation result in a significant change in CCNA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMC6 is perturbed and CCNA2 expression is quantified. Does this perturbation result in a significant change in CCNA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49232
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS14 and examine the expression of RRM2. Does perturbing RPS14 lead to a significant change in RRM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS14 and examine the expression of RRM2. Does perturbing RPS14 lead to a significant change in RRM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45081
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZCCHC9 is perturbed and ZWINT expression is measured. Determine whether ZWINT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZCCHC9 is perturbed and ZWINT expression is measured. Determine whether ZWINT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61189
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STAG2, does the expression profile of SRGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STAG2, does the expression profile of SRGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51747
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FNBP4 is perturbed and MCM3 expression is quantified. Does this perturbation result in a significant change in MCM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FNBP4 is perturbed and MCM3 expression is quantified. Does this perturbation result in a significant change in MCM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17032
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IWS1 and examine the expression of IWS1. Does perturbing IWS1 lead to a significant change in IWS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IWS1 and examine the expression of IWS1. Does perturbing IWS1 lead to a significant change in IWS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22441
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDAP1 is perturbed and PDAP1 expression is observed. Does this perturbation lead to a significant difference in PDAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDAP1 is perturbed and PDAP1 expression is observed. Does this perturbation lead to a significant difference in PDAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34443
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTC4 is perturbed and the expression of TTC4 is measured. Does this perturbation cause a significant change in TTC4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTC4 is perturbed and the expression of TTC4 is measured. Does this perturbation cause a significant change in TTC4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56210
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UTP11 is perturbed and the expression of UTP11 is measured. Determine whether UTP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UTP11 is perturbed and the expression of UTP11 is measured. Determine whether UTP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58486
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35A4 is perturbed and the expression of MASTL is measured. Determine whether MASTL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35A4 is perturbed and the expression of MASTL is measured. Determine whether MASTL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48696
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ABCB7 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ABCB7 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":244
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C9orf78 and then measure expression of C9orf78. Does this perturbation cause a significant change in C9orf78 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C9orf78 and then measure expression of C9orf78. Does this perturbation cause a significant change in C9orf78 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4714
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GSPT1 and examine the expression of DDIT4. Does perturbing GSPT1 lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GSPT1 and examine the expression of DDIT4. Does perturbing GSPT1 lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18731
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL23 is associated with a significant change in PCLAF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL23 is associated with a significant change in PCLAF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43685
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EEF1B2 and then measure expression of EHD1. Does this perturbation cause a significant change in EHD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EEF1B2 and then measure expression of EHD1. Does this perturbation cause a significant change in EHD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13764
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OGT and monitor C17orf58 expression. Decide whether this perturbation leads to a significant alteration in C17orf58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OGT and monitor C17orf58 expression. Decide whether this perturbation leads to a significant alteration in C17orf58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33578
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNC1H1, does the expression profile of ZMYND19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNC1H1, does the expression profile of ZMYND19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13387
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL22 is associated with a significant change in MT-ATP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL22 is associated with a significant change in MT-ATP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27315
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GUCD1, does the expression profile of SUGCT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GUCD1, does the expression profile of SUGCT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19347
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PABPC1 is perturbed and SERPINB2 expression is observed. Does this perturbation lead to a significant difference in SERPINB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PABPC1 is perturbed and SERPINB2 expression is observed. Does this perturbation lead to a significant difference in SERPINB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33953
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPSF6 is perturbed and the expression of SLC5A3 is measured. Determine whether SLC5A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPSF6 is perturbed and the expression of SLC5A3 is measured. Determine whether SLC5A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9686
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL11 is perturbed and RPL11 expression is quantified. Does this perturbation result in a significant change in RPL11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL11 is perturbed and RPL11 expression is quantified. Does this perturbation result in a significant change in RPL11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43352
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELP6 and then measure expression of PSAT1. Does this perturbation cause a significant change in PSAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELP6 and then measure expression of PSAT1. Does this perturbation cause a significant change in PSAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15194
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP9X is perturbed and MTHFD1L expression is measured. Determine whether MTHFD1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP9X is perturbed and MTHFD1L expression is measured. Determine whether MTHFD1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58429
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNRPG and monitor LRRCC1 expression. Decide whether this perturbation leads to a significant alteration in LRRCC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNRPG and monitor LRRCC1 expression. Decide whether this perturbation leads to a significant alteration in LRRCC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50248
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCNQ is perturbed and TCF19 expression is quantified. Does this perturbation result in a significant change in TCF19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCNQ is perturbed and TCF19 expression is quantified. Does this perturbation result in a significant change in TCF19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5642
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR1C is perturbed and AXL expression is quantified. Does this perturbation result in a significant change in AXL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR1C is perturbed and AXL expression is quantified. Does this perturbation result in a significant change in AXL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36512
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRMT1 and examine the expression of CCDC18. Does perturbing PRMT1 lead to a significant change in CCDC18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRMT1 and examine the expression of CCDC18. Does perturbing PRMT1 lead to a significant change in CCDC18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38601
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B5, does the expression profile of RRM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B5, does the expression profile of RRM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14217
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDC1 is perturbed and SDC1 expression is observed. Does this perturbation lead to a significant difference in SDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDC1 is perturbed and SDC1 expression is observed. Does this perturbation lead to a significant difference in SDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47113
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP1CB and then measure expression of TRAPPC8. Does this perturbation cause a significant change in TRAPPC8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP1CB and then measure expression of TRAPPC8. Does this perturbation cause a significant change in TRAPPC8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37714
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NAA20 is perturbed and the expression of GDF6 is measured. Determine whether GDF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NAA20 is perturbed and the expression of GDF6 is measured. Determine whether GDF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29536
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF7 is perturbed and SOX11 expression is measured. Determine whether SOX11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF7 is perturbed and SOX11 expression is measured. Determine whether SOX11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23279
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRD8 is associated with a significant change in MND1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRD8 is associated with a significant change in MND1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3935
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC16A is perturbed and KDELR3 expression is measured. Determine whether KDELR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC16A is perturbed and KDELR3 expression is measured. Determine whether KDELR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47319
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DR1 is perturbed and CMTR1 expression is measured. Determine whether CMTR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DR1 is perturbed and CMTR1 expression is measured. Determine whether CMTR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13129
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRCC1 is perturbed and ETFB expression is observed. Does this perturbation lead to a significant difference in ETFB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRCC1 is perturbed and ETFB expression is observed. Does this perturbation lead to a significant difference in ETFB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60423
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRAPPC11 is perturbed and the expression of YIF1A is measured. Does this perturbation cause a significant change in YIF1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRAPPC11 is perturbed and the expression of YIF1A is measured. Does this perturbation cause a significant change in YIF1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55510
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAT2A and then measure expression of MAT2A. Does this perturbation cause a significant change in MAT2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAT2A and then measure expression of MAT2A. Does this perturbation cause a significant change in MAT2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24754
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UROD is perturbed and the expression of THY1 is measured. Determine whether THY1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UROD is perturbed and the expression of THY1 is measured. Determine whether THY1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58166
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELL is perturbed and the expression of RPL22L1 is measured. Determine whether RPL22L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELL is perturbed and the expression of RPL22L1 is measured. Determine whether RPL22L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14956
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NAA38 is perturbed and STMN1 expression is quantified. Does this perturbation result in a significant change in STMN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NAA38 is perturbed and STMN1 expression is quantified. Does this perturbation result in a significant change in STMN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29652
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHCTF1 is perturbed and the expression of CD99 is measured. Does this perturbation cause a significant change in CD99 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHCTF1 is perturbed and the expression of CD99 is measured. Does this perturbation cause a significant change in CD99 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":970
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YY1 is perturbed and DMKN expression is observed. Does this perturbation lead to a significant difference in DMKN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YY1 is perturbed and DMKN expression is observed. Does this perturbation lead to a significant difference in DMKN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60943
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFA11 is associated with a significant change in AGK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFA11 is associated with a significant change in AGK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30445
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPUSD3 is perturbed and the expression of RPUSD3 is measured. Does this perturbation cause a significant change in RPUSD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPUSD3 is perturbed and the expression of RPUSD3 is measured. Does this perturbation cause a significant change in RPUSD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45870
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CTCF is perturbed and SHROOM3 expression is measured. Determine whether SHROOM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CTCF is perturbed and SHROOM3 expression is measured. Determine whether SHROOM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10079
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CRCP is perturbed and the expression of CRCP is measured. Does this perturbation cause a significant change in CRCP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CRCP is perturbed and the expression of CRCP is measured. Does this perturbation cause a significant change in CRCP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9690
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL33 is perturbed and MT-ATP8 expression is observed. Does this perturbation lead to a significant difference in MT-ATP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL33 is perturbed and MT-ATP8 expression is observed. Does this perturbation lead to a significant difference in MT-ATP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27523
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL41, does the expression profile of MRPL41 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL41, does the expression profile of MRPL41 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27757
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF18A and monitor ARL6IP6 expression. Decide whether this perturbation leads to a significant alteration in ARL6IP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF18A and monitor ARL6IP6 expression. Decide whether this perturbation leads to a significant alteration in ARL6IP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23128
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSP90B1 and examine the expression of HSP90B1. Does perturbing HSP90B1 lead to a significant change in HSP90B1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSP90B1 and examine the expression of HSP90B1. Does perturbing HSP90B1 lead to a significant change in HSP90B1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20761
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACTR8 is associated with a significant change in EXOSC8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACTR8 is associated with a significant change in EXOSC8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":755
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP62 is perturbed and ASF1B expression is observed. Does this perturbation lead to a significant difference in ASF1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP62 is perturbed and ASF1B expression is observed. Does this perturbation lead to a significant difference in ASF1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33303
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GUCD1 is associated with a significant change in WDR35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GUCD1 is associated with a significant change in WDR35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19335
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCID2 and examine the expression of SNHG25. Does perturbing PCID2 lead to a significant change in SNHG25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCID2 and examine the expression of SNHG25. Does perturbing PCID2 lead to a significant change in SNHG25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34341
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPLP2, does the expression profile of IFFO2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPLP2, does the expression profile of IFFO2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44687
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and TMED10 expression is observed. Does this perturbation lead to a significant difference in TMED10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and TMED10 expression is observed. Does this perturbation lead to a significant difference in TMED10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54543
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SDC1 and monitor NDUFS7 expression. Decide whether this perturbation leads to a significant alteration in NDUFS7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SDC1 and monitor NDUFS7 expression. Decide whether this perturbation leads to a significant alteration in NDUFS7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47128
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAF1D is perturbed and TAF1D expression is quantified. Does this perturbation result in a significant change in TAF1D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAF1D is perturbed and TAF1D expression is quantified. Does this perturbation result in a significant change in TAF1D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52682
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SMG7 and examine the expression of EPB41L4A-AS1. Does perturbing SMG7 lead to a significant change in EPB41L4A-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SMG7 and examine the expression of EPB41L4A-AS1. Does perturbing SMG7 lead to a significant change in EPB41L4A-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49371
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAD2L2 is perturbed and MAD2L2 expression is quantified. Does this perturbation result in a significant change in MAD2L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAD2L2 is perturbed and MAD2L2 expression is quantified. Does this perturbation result in a significant change in MAD2L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24552
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL5 is perturbed and PCLAF expression is quantified. Does this perturbation result in a significant change in PCLAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL5 is perturbed and PCLAF expression is quantified. Does this perturbation result in a significant change in PCLAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44442
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSTK and monitor GANAB expression. Decide whether this perturbation leads to a significant alteration in GANAB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSTK and monitor GANAB expression. Decide whether this perturbation leads to a significant alteration in GANAB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40228
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DIS3 is perturbed and the expression of MTHFD1 is measured. Does this perturbation cause a significant change in MTHFD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DIS3 is perturbed and the expression of MTHFD1 is measured. Does this perturbation cause a significant change in MTHFD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12360
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GEMIN8 is perturbed and POLE2 expression is observed. Does this perturbation lead to a significant difference in POLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GEMIN8 is perturbed and POLE2 expression is observed. Does this perturbation lead to a significant difference in POLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17593
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAXX is perturbed and the expression of COMMD1 is measured. Determine whether COMMD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAXX is perturbed and the expression of COMMD1 is measured. Determine whether COMMD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10686
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRSF6 is associated with a significant change in FAM200B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRSF6 is associated with a significant change in FAM200B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51535
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS2 and then measure expression of MRPS12. Does this perturbation cause a significant change in MRPS12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS2 and then measure expression of MRPS12. Does this perturbation cause a significant change in MRPS12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46744
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCM4 is perturbed and MED23 expression is measured. Determine whether MED23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCM4 is perturbed and MED23 expression is measured. Determine whether MED23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25199
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TRAPPC4 is perturbed and RAD51 expression is observed. Does this perturbation lead to a significant difference in RAD51 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TRAPPC4 is perturbed and RAD51 expression is observed. Does this perturbation lead to a significant difference in RAD51 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55573
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MMS22L is perturbed and SGO1 expression is observed. Does this perturbation lead to a significant difference in SGO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MMS22L is perturbed and SGO1 expression is observed. Does this perturbation lead to a significant difference in SGO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26643
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPIL2 is perturbed and the expression of PPIL2 is measured. Determine whether PPIL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPIL2 is perturbed and the expression of PPIL2 is measured. Determine whether PPIL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37596
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL26 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL26 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43774
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KPNA6 is perturbed and the expression of ECHS1 is measured. Determine whether ECHS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KPNA6 is perturbed and the expression of ECHS1 is measured. Determine whether ECHS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23296
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTC1 is perturbed and the expression of TTC1 is measured. Determine whether TTC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTC1 is perturbed and the expression of TTC1 is measured. Determine whether TTC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56136
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HAUS6 is perturbed and HAUS6 expression is observed. Does this perturbation lead to a significant difference in HAUS6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HAUS6 is perturbed and HAUS6 expression is observed. Does this perturbation lead to a significant difference in HAUS6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19653
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPA2, does the expression profile of CMC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPA2, does the expression profile of CMC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37437
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NFATC2IP is associated with a significant change in CHCHD7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NFATC2IP is associated with a significant change in CHCHD7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31285
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAA20 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAA20 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29544
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMA1 is perturbed and ATPAF1 expression is observed. Does this perturbation lead to a significant difference in ATPAF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMA1 is perturbed and ATPAF1 expression is observed. Does this perturbation lead to a significant difference in ATPAF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39103
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TPX2 is perturbed and DDX11 expression is quantified. Does this perturbation result in a significant change in DDX11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TPX2 is perturbed and DDX11 expression is quantified. Does this perturbation result in a significant change in DDX11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55422
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS26 and examine the expression of CDC6. Does perturbing RPS26 lead to a significant change in CDC6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS26 and examine the expression of CDC6. Does perturbing RPS26 lead to a significant change in CDC6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45471
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BOP1 is perturbed and CENPE expression is observed. Does this perturbation lead to a significant difference in CENPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BOP1 is perturbed and CENPE expression is observed. Does this perturbation lead to a significant difference in CENPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3763
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLMN is perturbed and RBFA expression is measured. Determine whether RBFA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLMN is perturbed and RBFA expression is measured. Determine whether RBFA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18009
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KRT8 is perturbed and KRT8 expression is observed. Does this perturbation lead to a significant difference in KRT8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KRT8 is perturbed and KRT8 expression is observed. Does this perturbation lead to a significant difference in KRT8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23443
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COG2 is perturbed and ARPIN expression is measured. Determine whether ARPIN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COG2 is perturbed and ARPIN expression is measured. Determine whether ARPIN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8539
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SKP1 is perturbed and the expression of MUL1 is measured. Determine whether MUL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SKP1 is perturbed and the expression of MUL1 is measured. Determine whether MUL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48466
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS33, does the expression profile of ARL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS33, does the expression profile of ARL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28727
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ANAPC13 is perturbed and the expression of CEP63 is measured. Does this perturbation cause a significant change in CEP63 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ANAPC13 is perturbed and the expression of CEP63 is measured. Does this perturbation cause a significant change in CEP63 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1370
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NPLOC4 and then measure expression of DDIT3. Does this perturbation cause a significant change in DDIT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NPLOC4 and then measure expression of DDIT3. Does this perturbation cause a significant change in DDIT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32314
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor LMNB1 expression. Decide whether this perturbation leads to a significant alteration in LMNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor LMNB1 expression. Decide whether this perturbation leads to a significant alteration in LMNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39878
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RNMT is perturbed and RPL22L1 expression is quantified. Does this perturbation result in a significant change in RPL22L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RNMT is perturbed and RPL22L1 expression is quantified. Does this perturbation result in a significant change in RPL22L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42872
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR26 is perturbed and the expression of MTFR2 is measured. Determine whether MTFR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR26 is perturbed and the expression of MTFR2 is measured. Determine whether MTFR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59656
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CPSF2 is perturbed and RNGTT expression is observed. Does this perturbation lead to a significant difference in RNGTT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CPSF2 is perturbed and RNGTT expression is observed. Does this perturbation lead to a significant difference in RNGTT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9583
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP53RK and examine the expression of ATF4. Does perturbing TP53RK lead to a significant change in ATF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP53RK and examine the expression of ATF4. Does perturbing TP53RK lead to a significant change in ATF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55251
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCNC and monitor TGM2 expression. Decide whether this perturbation leads to a significant alteration in TGM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCNC and monitor TGM2 expression. Decide whether this perturbation leads to a significant alteration in TGM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5488
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL26L1 and examine the expression of RPL26L1. Does perturbing RPL26L1 lead to a significant change in RPL26L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL26L1 and examine the expression of RPL26L1. Does perturbing RPL26L1 lead to a significant change in RPL26L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43801
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CPSF3 and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CPSF3 and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9624
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF6 and examine the expression of DTNBP1. Does perturbing PRPF6 lead to a significant change in DTNBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF6 and examine the expression of DTNBP1. Does perturbing PRPF6 lead to a significant change in DTNBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38951
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YEATS2 and then measure expression of RPL22L1. Does this perturbation cause a significant change in RPL22L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YEATS2 and then measure expression of RPL22L1. Does this perturbation cause a significant change in RPL22L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60754
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KDM6A, does the expression profile of KDM6A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KDM6A, does the expression profile of KDM6A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22927
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FBXO5 is associated with a significant change in CEP63 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FBXO5 is associated with a significant change in CEP63 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16755
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, THOC5 is perturbed and the expression of POLE2 is measured. Determine whether POLE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, THOC5 is perturbed and the expression of POLE2 is measured. Determine whether POLE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53956
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPH1 and monitor RBM3 expression. Decide whether this perturbation leads to a significant alteration in RBM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPH1 and monitor RBM3 expression. Decide whether this perturbation leads to a significant alteration in RBM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20438
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PAF1 is perturbed and the expression of CDKN3 is measured. Does this perturbation cause a significant change in CDKN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PAF1 is perturbed and the expression of CDKN3 is measured. Does this perturbation cause a significant change in CDKN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34020
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ALG14 is associated with a significant change in SDF2L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ALG14 is associated with a significant change in SDF2L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1185
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR2E and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR2E and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36744
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC25A3 is perturbed and PGBD1 expression is quantified. Does this perturbation result in a significant change in PGBD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC25A3 is perturbed and PGBD1 expression is quantified. Does this perturbation result in a significant change in PGBD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48652
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP37 is perturbed and the expression of MCM6 is measured. Determine whether MCM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP37 is perturbed and the expression of MCM6 is measured. Determine whether MCM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58266
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SART1 and monitor DNMT1 expression. Decide whether this perturbation leads to a significant alteration in DNMT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SART1 and monitor DNMT1 expression. Decide whether this perturbation leads to a significant alteration in DNMT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46798
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf53 is perturbed and NUSAP1 expression is observed. Does this perturbation lead to a significant difference in NUSAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf53 is perturbed and NUSAP1 expression is observed. Does this perturbation lead to a significant difference in NUSAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4443
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF5A is perturbed and EIF5A expression is observed. Does this perturbation lead to a significant difference in EIF5A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF5A is perturbed and EIF5A expression is observed. Does this perturbation lead to a significant difference in EIF5A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14853
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor TRIB3 expression. Decide whether this perturbation leads to a significant alteration in TRIB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor TRIB3 expression. Decide whether this perturbation leads to a significant alteration in TRIB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14108
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, INTS5 is perturbed and the expression of PARPBP is measured. Does this perturbation cause a significant change in PARPBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, INTS5 is perturbed and the expression of PARPBP is measured. Does this perturbation cause a significant change in PARPBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22000
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C12orf45 and then measure expression of CKAP2L. Does this perturbation cause a significant change in CKAP2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C12orf45 and then measure expression of CKAP2L. Does this perturbation cause a significant change in CKAP2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4364
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX5B and then measure expression of KATNA1. Does this perturbation cause a significant change in KATNA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX5B and then measure expression of KATNA1. Does this perturbation cause a significant change in KATNA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9344
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRCAP is perturbed and the expression of TXN2 is measured. Does this perturbation cause a significant change in TXN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRCAP is perturbed and the expression of TXN2 is measured. Does this perturbation cause a significant change in TXN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50980
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAF2 is associated with a significant change in SPAG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAF2 is associated with a significant change in SPAG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52735
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX8 is perturbed and the expression of DDIT3 is measured. Does this perturbation cause a significant change in DDIT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX8 is perturbed and the expression of DDIT3 is measured. Does this perturbation cause a significant change in DDIT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12240
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TPT1 is perturbed and the expression of ATP6V0E1 is measured. Does this perturbation cause a significant change in ATP6V0E1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TPT1 is perturbed and the expression of ATP6V0E1 is measured. Does this perturbation cause a significant change in ATP6V0E1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55380
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SKP2 is perturbed and SKP2 expression is observed. Does this perturbation lead to a significant difference in SKP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SKP2 is perturbed and SKP2 expression is observed. Does this perturbation lead to a significant difference in SKP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48493
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WBP11 and then measure expression of KHDRBS3. Does this perturbation cause a significant change in KHDRBS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WBP11 and then measure expression of KHDRBS3. Does this perturbation cause a significant change in KHDRBS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59424
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AAR2 is perturbed and RFC2 expression is measured. Determine whether RFC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AAR2 is perturbed and RFC2 expression is measured. Determine whether RFC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of METTL17, does the expression profile of SSR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of METTL17, does the expression profile of SSR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26107
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb WDR5 and monitor SYNGR1 expression. Decide whether this perturbation leads to a significant alteration in SYNGR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb WDR5 and monitor SYNGR1 expression. Decide whether this perturbation leads to a significant alteration in SYNGR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59888
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FAM133B and monitor GINS1 expression. Decide whether this perturbation leads to a significant alteration in GINS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FAM133B and monitor GINS1 expression. Decide whether this perturbation leads to a significant alteration in GINS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16308
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD5 is perturbed and the expression of RPL22L1 is measured. Does this perturbation cause a significant change in RPL22L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD5 is perturbed and the expression of RPL22L1 is measured. Does this perturbation cause a significant change in RPL22L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47780
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS23 and then measure expression of CLSPN. Does this perturbation cause a significant change in CLSPN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS23 and then measure expression of CLSPN. Does this perturbation cause a significant change in CLSPN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45364
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAST and examine the expression of MT-ND3. Does perturbing CAST lead to a significant change in MT-ND3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAST and examine the expression of MT-ND3. Does perturbing CAST lead to a significant change in MT-ND3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5061
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRRM2 is associated with a significant change in ZNF580 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRRM2 is associated with a significant change in ZNF580 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51315
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EXOSC3 and monitor ERCC6L expression. Decide whether this perturbation leads to a significant alteration in ERCC6L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EXOSC3 and monitor ERCC6L expression. Decide whether this perturbation leads to a significant alteration in ERCC6L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16068
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDR92, does the expression profile of COPG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDR92, does the expression profile of COPG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60187
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RRM2 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RRM2 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45975
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGPEP1 and examine the expression of MLH1. Does perturbing PGPEP1 lead to a significant change in MLH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGPEP1 and examine the expression of MLH1. Does perturbing PGPEP1 lead to a significant change in MLH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35261
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ENY2, does the expression profile of RBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ENY2, does the expression profile of RBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15377
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of USP7 is associated with a significant change in IGFBP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of USP7 is associated with a significant change in IGFBP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58375
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, INO80C is perturbed and the expression of INO80C is measured. Does this perturbation cause a significant change in INO80C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, INO80C is perturbed and the expression of INO80C is measured. Does this perturbation cause a significant change in INO80C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21600
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL27 is associated with a significant change in PCLAF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL27 is associated with a significant change in PCLAF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43835
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP14 is perturbed and the expression of USP14 is measured. Determine whether USP14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP14 is perturbed and the expression of USP14 is measured. Determine whether USP14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58236
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCF11 and examine the expression of KCNK2. Does perturbing PCF11 lead to a significant change in KCNK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCF11 and examine the expression of KCNK2. Does perturbing PCF11 lead to a significant change in KCNK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34311
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PNPT1 is associated with a significant change in MT-CO2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PNPT1 is associated with a significant change in MT-CO2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36105
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARCN1, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARCN1, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1767
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBE2Z is perturbed and the expression of SLC39A8 is measured. Does this perturbation cause a significant change in SLC39A8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBE2Z is perturbed and the expression of SLC39A8 is measured. Does this perturbation cause a significant change in SLC39A8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57380
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNOT2 and examine the expression of NRG1. Does perturbing CNOT2 lead to a significant change in NRG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNOT2 and examine the expression of NRG1. Does perturbing CNOT2 lead to a significant change in NRG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8351
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb USP9X and examine the expression of MTHFD1L. Does perturbing USP9X lead to a significant change in MTHFD1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb USP9X and examine the expression of MTHFD1L. Does perturbing USP9X lead to a significant change in MTHFD1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58421
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GFER is perturbed and POC5 expression is observed. Does this perturbation lead to a significant difference in POC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GFER is perturbed and POC5 expression is observed. Does this perturbation lead to a significant difference in POC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17683
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, THG1L is perturbed and the expression of PSAT1 is measured. Does this perturbation cause a significant change in PSAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, THG1L is perturbed and the expression of PSAT1 is measured. Does this perturbation cause a significant change in PSAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53830
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1B2, does the expression profile of MSMO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1B2, does the expression profile of MSMO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2897
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMC1 is perturbed and MAP1A expression is measured. Determine whether MAP1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMC1 is perturbed and MAP1A expression is measured. Determine whether MAP1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39509
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UMPS and examine the expression of UMPS. Does perturbing UMPS lead to a significant change in UMPS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UMPS and examine the expression of UMPS. Does perturbing UMPS lead to a significant change in UMPS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57691
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AAR2, does the expression profile of PLEKHA5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AAR2, does the expression profile of PLEKHA5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP155 and examine the expression of XPO7. Does perturbing NUP155 lead to a significant change in XPO7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP155 and examine the expression of XPO7. Does perturbing NUP155 lead to a significant change in XPO7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33091
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GRB2 is perturbed and FTL expression is measured. Determine whether FTL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GRB2 is perturbed and FTL expression is measured. Determine whether FTL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18579
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TOPBP1 is perturbed and C1QL1 expression is observed. Does this perturbation lead to a significant difference in C1QL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TOPBP1 is perturbed and C1QL1 expression is observed. Does this perturbation lead to a significant difference in C1QL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55133
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSCB is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSCB is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20643
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDT1 is perturbed and SUGCT expression is measured. Determine whether SUGCT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDT1 is perturbed and SUGCT expression is measured. Determine whether SUGCT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6619
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL26 is perturbed and the expression of CDKN3 is measured. Determine whether CDKN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL26 is perturbed and the expression of CDKN3 is measured. Determine whether CDKN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43796
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP6C is perturbed and the expression of PPP6C is measured. Determine whether PPP6C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP6C is perturbed and the expression of PPP6C is measured. Determine whether PPP6C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38166
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RSL1D1 is associated with a significant change in RSL1D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RSL1D1 is associated with a significant change in RSL1D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46205
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRS1 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRS1 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46176
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF4G1 is perturbed and TM4SF1 expression is observed. Does this perturbation lead to a significant difference in TM4SF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF4G1 is perturbed and TM4SF1 expression is observed. Does this perturbation lead to a significant difference in TM4SF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14743
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4G2 and then measure expression of EIF4G2. Does this perturbation cause a significant change in EIF4G2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4G2 and then measure expression of EIF4G2. Does this perturbation cause a significant change in EIF4G2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14764
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NKAPD1 and monitor NKAPD1 expression. Decide whether this perturbation leads to a significant alteration in NKAPD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NKAPD1 and monitor NKAPD1 expression. Decide whether this perturbation leads to a significant alteration in NKAPD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31608
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2F1 is associated with a significant change in VPS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2F1 is associated with a significant change in VPS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18915
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS17 is perturbed and RBL1 expression is observed. Does this perturbation lead to a significant difference in RBL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS17 is perturbed and RBL1 expression is observed. Does this perturbation lead to a significant difference in RBL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45163
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPS6 and monitor HJURP expression. Decide whether this perturbation leads to a significant alteration in HJURP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPS6 and monitor HJURP expression. Decide whether this perturbation leads to a significant alteration in HJURP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8998
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCM3AP is perturbed and DNAJC9 expression is measured. Determine whether DNAJC9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCM3AP is perturbed and DNAJC9 expression is measured. Determine whether DNAJC9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25169
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMARCE1 is perturbed and the expression of FAR2 is measured. Determine whether FAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMARCE1 is perturbed and the expression of FAR2 is measured. Determine whether FAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49076
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RAB18 is perturbed and the expression of NAGPA is measured. Does this perturbation cause a significant change in NAGPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RAB18 is perturbed and the expression of NAGPA is measured. Does this perturbation cause a significant change in NAGPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40750
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF38A is perturbed and CCNE2 expression is quantified. Does this perturbation result in a significant change in CCNE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF38A is perturbed and CCNE2 expression is quantified. Does this perturbation result in a significant change in CCNE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38802
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF2H3 is perturbed and PSMC3IP expression is quantified. Does this perturbation result in a significant change in PSMC3IP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF2H3 is perturbed and PSMC3IP expression is quantified. Does this perturbation result in a significant change in PSMC3IP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19042
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPE is perturbed and RUSC1 expression is measured. Determine whether RUSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPE is perturbed and RUSC1 expression is measured. Determine whether RUSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8799
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ADRM1 and examine the expression of ADRM1. Does perturbing ADRM1 lead to a significant change in ADRM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ADRM1 and examine the expression of ADRM1. Does perturbing ADRM1 lead to a significant change in ADRM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":841
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR36 and examine the expression of KIF2C. Does perturbing WDR36 lead to a significant change in KIF2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR36 and examine the expression of KIF2C. Does perturbing WDR36 lead to a significant change in KIF2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59741
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL23 is perturbed and the expression of PCLAF is measured. Determine whether PCLAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL23 is perturbed and the expression of PCLAF is measured. Determine whether PCLAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43686
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGBP1 is perturbed and LUCAT1 expression is quantified. Does this perturbation result in a significant change in LUCAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGBP1 is perturbed and LUCAT1 expression is quantified. Does this perturbation result in a significant change in LUCAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21292
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNMT1 is perturbed and DNMT1 expression is measured. Determine whether DNMT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNMT1 is perturbed and DNMT1 expression is measured. Determine whether DNMT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12799
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FNBP4, does the expression profile of FNBP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FNBP4, does the expression profile of FNBP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17017
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP2A is perturbed and the expression of HMMR is measured. Does this perturbation cause a significant change in HMMR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP2A is perturbed and the expression of HMMR is measured. Does this perturbation cause a significant change in HMMR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7460
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNHIT2 and monitor LMNB1 expression. Decide whether this perturbation leads to a significant alteration in LMNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNHIT2 and monitor LMNB1 expression. Decide whether this perturbation leads to a significant alteration in LMNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61848
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPA1 and monitor NUPR1 expression. Decide whether this perturbation leads to a significant alteration in NUPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPA1 and monitor NUPR1 expression. Decide whether this perturbation leads to a significant alteration in NUPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37408
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2M is perturbed and NQO1 expression is quantified. Does this perturbation result in a significant change in NQO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2M is perturbed and NQO1 expression is quantified. Does this perturbation result in a significant change in NQO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57322
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMC2 is perturbed and SMC2 expression is quantified. Does this perturbation result in a significant change in SMC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMC2 is perturbed and SMC2 expression is quantified. Does this perturbation result in a significant change in SMC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49112
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCDC174 is perturbed and MCM10 expression is observed. Does this perturbation lead to a significant difference in MCM10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCDC174 is perturbed and MCM10 expression is observed. Does this perturbation lead to a significant difference in MCM10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5263
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLP1 is perturbed and the expression of TCF19 is measured. Determine whether TCF19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLP1 is perturbed and the expression of TCF19 is measured. Determine whether TCF19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7966
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBCB is perturbed and the expression of SPC25 is measured. Does this perturbation cause a significant change in SPC25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBCB is perturbed and the expression of SPC25 is measured. Does this perturbation cause a significant change in SPC25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53100
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM12 is perturbed and the expression of TGOLN2 is measured. Does this perturbation cause a significant change in TGOLN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM12 is perturbed and the expression of TGOLN2 is measured. Does this perturbation cause a significant change in TGOLN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24170
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDK9, does the expression profile of MARCKSL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDK9, does the expression profile of MARCKSL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6577
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LIMS1 is perturbed and the expression of PWP1 is measured. Determine whether PWP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LIMS1 is perturbed and the expression of PWP1 is measured. Determine whether PWP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23906
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND1 is perturbed and IGFBP3 expression is observed. Does this perturbation lead to a significant difference in IGFBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND1 is perturbed and IGFBP3 expression is observed. Does this perturbation lead to a significant difference in IGFBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5513
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL45, does the expression profile of MT-ND2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL45, does the expression profile of MT-ND2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27897
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3B is perturbed and the expression of NIBAN1 is measured. Does this perturbation cause a significant change in NIBAN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3B is perturbed and the expression of NIBAN1 is measured. Does this perturbation cause a significant change in NIBAN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51870
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLG and examine the expression of MT-ND6. Does perturbing POLG lead to a significant change in MT-ND6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLG and examine the expression of MT-ND6. Does perturbing POLG lead to a significant change in MT-ND6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36391
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPP30 is perturbed and the expression of SKA3 is measured. Does this perturbation cause a significant change in SKA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPP30 is perturbed and the expression of SKA3 is measured. Does this perturbation cause a significant change in SKA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44820
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTF2 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTF2 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56249
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR3 and then measure expression of SYNE2. Does this perturbation cause a significant change in SYNE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR3 and then measure expression of SYNE2. Does this perturbation cause a significant change in SYNE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59674
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to URM1 and then measure expression of NUPR1. Does this perturbation cause a significant change in NUPR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to URM1 and then measure expression of NUPR1. Does this perturbation cause a significant change in NUPR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58114
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YKT6, does the expression profile of YKT6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YKT6, does the expression profile of YKT6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60817
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCDC6 is perturbed and CCDC6 expression is quantified. Does this perturbation result in a significant change in CCDC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCDC6 is perturbed and CCDC6 expression is quantified. Does this perturbation result in a significant change in CCDC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5312
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA14 and examine the expression of MDFIC. Does perturbing HSPA14 lead to a significant change in MDFIC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA14 and examine the expression of MDFIC. Does perturbing HSPA14 lead to a significant change in MDFIC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20811
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb YBX3 and monitor YBX3 expression. Decide whether this perturbation leads to a significant alteration in YBX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YBX3 and monitor YBX3 expression. Decide whether this perturbation leads to a significant alteration in YBX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60728
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPRTN and examine the expression of RMI2. Does perturbing SPRTN lead to a significant change in RMI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPRTN and examine the expression of RMI2. Does perturbing SPRTN lead to a significant change in RMI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50841
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS18 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS18 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45195
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NLE1 and monitor DTL expression. Decide whether this perturbation leads to a significant alteration in DTL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NLE1 and monitor DTL expression. Decide whether this perturbation leads to a significant alteration in DTL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31648
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RAC1 is perturbed and RAC1 expression is quantified. Does this perturbation result in a significant change in RAC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RAC1 is perturbed and RAC1 expression is quantified. Does this perturbation result in a significant change in RAC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40922
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LDB1 is perturbed and MDH1 expression is measured. Determine whether MDH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LDB1 is perturbed and MDH1 expression is measured. Determine whether MDH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23779
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NELFB and then measure expression of RPL22L1. Does this perturbation cause a significant change in RPL22L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NELFB and then measure expression of RPL22L1. Does this perturbation cause a significant change in RPL22L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31094
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISG20L2 is perturbed and UHRF1 expression is observed. Does this perturbation lead to a significant difference in UHRF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISG20L2 is perturbed and UHRF1 expression is observed. Does this perturbation lead to a significant difference in UHRF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22343
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMAGP is perturbed and SMAGP expression is observed. Does this perturbation lead to a significant difference in SMAGP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMAGP is perturbed and SMAGP expression is observed. Does this perturbation lead to a significant difference in SMAGP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48963
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IFITM2 and then measure expression of CHRNA5. Does this perturbation cause a significant change in CHRNA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IFITM2 and then measure expression of CHRNA5. Does this perturbation cause a significant change in CHRNA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21234
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GPN1 is perturbed and the expression of NEK2 is measured. Does this perturbation cause a significant change in NEK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GPN1 is perturbed and the expression of NEK2 is measured. Does this perturbation cause a significant change in NEK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18420
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCAR1 is perturbed and HNRNPD expression is quantified. Does this perturbation result in a significant change in HNRNPD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCAR1 is perturbed and HNRNPD expression is quantified. Does this perturbation result in a significant change in HNRNPD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5152
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PIK3C3 is perturbed and HMGCS1 expression is observed. Does this perturbation lead to a significant difference in HMGCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PIK3C3 is perturbed and HMGCS1 expression is observed. Does this perturbation lead to a significant difference in HMGCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35633
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA6 and then measure expression of ELOVL6. Does this perturbation cause a significant change in ELOVL6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA6 and then measure expression of ELOVL6. Does this perturbation cause a significant change in ELOVL6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30564
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GARS is associated with a significant change in PSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GARS is associated with a significant change in PSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17365
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YBX1 is associated with a significant change in YBX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YBX1 is associated with a significant change in YBX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60715
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JMJD6 and then measure expression of JMJD6. Does this perturbation cause a significant change in JMJD6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JMJD6 and then measure expression of JMJD6. Does this perturbation cause a significant change in JMJD6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22524
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SUPT20H and examine the expression of SUPT20H. Does perturbing SUPT20H lead to a significant change in SUPT20H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SUPT20H and examine the expression of SUPT20H. Does perturbing SUPT20H lead to a significant change in SUPT20H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52161
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GPS1 is perturbed and PCLAF expression is quantified. Does this perturbation result in a significant change in PCLAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GPS1 is perturbed and PCLAF expression is quantified. Does this perturbation result in a significant change in PCLAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18522
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS19BP1 is perturbed and the expression of SYNE2 is measured. Does this perturbation cause a significant change in SYNE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS19BP1 is perturbed and the expression of SYNE2 is measured. Does this perturbation cause a significant change in SYNE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45240
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DRG1 is perturbed and MEST expression is observed. Does this perturbation lead to a significant difference in MEST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DRG1 is perturbed and MEST expression is observed. Does this perturbation lead to a significant difference in MEST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13193
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NDUFA8 and monitor NDUFA8 expression. Decide whether this perturbation leads to a significant alteration in NDUFA8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NDUFA8 and monitor NDUFA8 expression. Decide whether this perturbation leads to a significant alteration in NDUFA8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30578
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BTF3L4 is associated with a significant change in BTF3L4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BTF3L4 is associated with a significant change in BTF3L4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4145
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL44 and monitor MRPL44 expression. Decide whether this perturbation leads to a significant alteration in MRPL44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL44 and monitor MRPL44 expression. Decide whether this perturbation leads to a significant alteration in MRPL44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27848
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL36A is perturbed and INTS7 expression is measured. Determine whether INTS7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL36A is perturbed and INTS7 expression is measured. Determine whether INTS7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44209
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BRF1 is perturbed and the expression of SLC6A6 is measured. Determine whether SLC6A6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BRF1 is perturbed and the expression of SLC6A6 is measured. Determine whether SLC6A6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3966
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHMP2A and then measure expression of WDR34. Does this perturbation cause a significant change in WDR34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHMP2A and then measure expression of WDR34. Does this perturbation cause a significant change in WDR34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7454
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPAIN is perturbed and the expression of KIF20A is measured. Does this perturbation cause a significant change in KIF20A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPAIN is perturbed and the expression of KIF20A is measured. Does this perturbation cause a significant change in KIF20A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43080
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COQ4 is perturbed and SNRPG expression is observed. Does this perturbation lead to a significant difference in SNRPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COQ4 is perturbed and SNRPG expression is observed. Does this perturbation lead to a significant difference in SNRPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9113
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL7L1 is perturbed and RPL7L1 expression is quantified. Does this perturbation result in a significant change in RPL7L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL7L1 is perturbed and RPL7L1 expression is quantified. Does this perturbation result in a significant change in RPL7L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44522
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BARD1 is perturbed and the expression of WDR76 is measured. Determine whether WDR76 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BARD1 is perturbed and the expression of WDR76 is measured. Determine whether WDR76 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3346
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPY19L4 is perturbed and ORAI1 expression is quantified. Does this perturbation result in a significant change in ORAI1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPY19L4 is perturbed and ORAI1 expression is quantified. Does this perturbation result in a significant change in ORAI1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13092
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TEFM is perturbed and MT-ND4L expression is measured. Determine whether MT-ND4L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TEFM is perturbed and MT-ND4L expression is measured. Determine whether MT-ND4L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53399
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THG1L is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THG1L is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53849
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDX41 is perturbed and GSDMD expression is observed. Does this perturbation lead to a significant difference in GSDMD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDX41 is perturbed and GSDMD expression is observed. Does this perturbation lead to a significant difference in GSDMD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11463
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PFN1 is perturbed and IL1B expression is quantified. Does this perturbation result in a significant change in IL1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PFN1 is perturbed and IL1B expression is quantified. Does this perturbation result in a significant change in IL1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35122
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MALSU1 and then measure expression of MT-ND3. Does this perturbation cause a significant change in MT-ND3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MALSU1 and then measure expression of MT-ND3. Does this perturbation cause a significant change in MT-ND3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24644
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COX11 is perturbed and SCG5 expression is observed. Does this perturbation lead to a significant difference in SCG5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COX11 is perturbed and SCG5 expression is observed. Does this perturbation lead to a significant difference in SCG5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9223
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SUPV3L1 and monitor MTRNR2L8 expression. Decide whether this perturbation leads to a significant alteration in MTRNR2L8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SUPV3L1 and monitor MTRNR2L8 expression. Decide whether this perturbation leads to a significant alteration in MTRNR2L8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52278
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NPM1 and monitor NPM1 expression. Decide whether this perturbation leads to a significant alteration in NPM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NPM1 and monitor NPM1 expression. Decide whether this perturbation leads to a significant alteration in NPM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32348
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF39 is perturbed and the expression of PRPF39 is measured. Determine whether PRPF39 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF39 is perturbed and the expression of PRPF39 is measured. Determine whether PRPF39 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38846
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MVD and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MVD and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29248
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PNPT1, does the expression profile of MT-ND6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PNPT1, does the expression profile of MT-ND6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36097
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NOP56 and monitor FLNA expression. Decide whether this perturbation leads to a significant alteration in FLNA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NOP56 and monitor FLNA expression. Decide whether this perturbation leads to a significant alteration in FLNA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32238
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MICOS10 is perturbed and MICOS10 expression is quantified. Does this perturbation result in a significant change in MICOS10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MICOS10 is perturbed and MICOS10 expression is quantified. Does this perturbation result in a significant change in MICOS10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26282
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTK2 is associated with a significant change in BRCA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTK2 is associated with a significant change in BRCA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40345
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPP21, does the expression profile of RPP21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPP21, does the expression profile of RPP21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44807
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL36 is associated with a significant change in LAMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL36 is associated with a significant change in LAMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27615
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COX5B is perturbed and LMAN2L expression is quantified. Does this perturbation result in a significant change in LMAN2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COX5B is perturbed and LMAN2L expression is quantified. Does this perturbation result in a significant change in LMAN2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9352
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELAC2 is perturbed and the expression of PSAT1 is measured. Determine whether PSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELAC2 is perturbed and the expression of PSAT1 is measured. Determine whether PSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14926
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTU2, does the expression profile of NUPR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTU2, does the expression profile of NUPR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10207
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COG1 and examine the expression of COG1. Does perturbing COG1 lead to a significant change in COG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COG1 and examine the expression of COG1. Does perturbing COG1 lead to a significant change in COG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8501
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHAF1A is perturbed and the expression of ASF1B is measured. Determine whether ASF1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHAF1A is perturbed and the expression of ASF1B is measured. Determine whether ASF1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7146
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF3 is perturbed and the expression of NDUFAF3 is measured. Does this perturbation cause a significant change in NDUFAF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF3 is perturbed and the expression of NDUFAF3 is measured. Does this perturbation cause a significant change in NDUFAF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30630
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GFER is perturbed and APTR expression is measured. Determine whether APTR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GFER is perturbed and APTR expression is measured. Determine whether APTR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17699
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PCBP1, does the expression profile of ACADVL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PCBP1, does the expression profile of ACADVL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34247
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JMJD6 is perturbed and the expression of ZNF33A is measured. Determine whether ZNF33A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JMJD6 is perturbed and the expression of ZNF33A is measured. Determine whether ZNF33A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22516
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POP1 is associated with a significant change in SYNE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POP1 is associated with a significant change in SYNE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37245
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CKAP5 and monitor PCSK1N expression. Decide whether this perturbation leads to a significant alteration in PCSK1N expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CKAP5 and monitor PCSK1N expression. Decide whether this perturbation leads to a significant alteration in PCSK1N expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7818
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in YIF1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in YIF1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54585
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRF and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRF and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51004
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V1F and then measure expression of TMEM160. Does this perturbation cause a significant change in TMEM160 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V1F and then measure expression of TMEM160. Does this perturbation cause a significant change in TMEM160 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3014
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OIP5 and monitor TOP2A expression. Decide whether this perturbation leads to a significant alteration in TOP2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OIP5 and monitor TOP2A expression. Decide whether this perturbation leads to a significant alteration in TOP2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33628
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STARD7 is perturbed and the expression of STARD7 is measured. Does this perturbation cause a significant change in STARD7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STARD7 is perturbed and the expression of STARD7 is measured. Does this perturbation cause a significant change in STARD7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51750
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACTR1B is perturbed and the expression of GOLGA4 is measured. Does this perturbation cause a significant change in GOLGA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACTR1B is perturbed and the expression of GOLGA4 is measured. Does this perturbation cause a significant change in GOLGA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":650
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARS2 and examine the expression of RMI1. Does perturbing FARS2 lead to a significant change in RMI1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARS2 and examine the expression of RMI1. Does perturbing FARS2 lead to a significant change in RMI1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16451
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NLE1 is perturbed and KIF4A expression is measured. Determine whether KIF4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NLE1 is perturbed and KIF4A expression is measured. Determine whether KIF4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31629
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL37 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL37 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27658
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNRNP25, does the expression profile of SNRNP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNRNP25, does the expression profile of SNRNP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49777
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5ME is perturbed and ATP5ME expression is quantified. Does this perturbation result in a significant change in ATP5ME expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5ME is perturbed and ATP5ME expression is quantified. Does this perturbation result in a significant change in ATP5ME expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2582
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRCA2 and examine the expression of BRI3BP. Does perturbing BRCA2 lead to a significant change in BRI3BP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRCA2 and examine the expression of BRI3BP. Does perturbing BRCA2 lead to a significant change in BRI3BP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3861
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SDHC and examine the expression of SLC38A1. Does perturbing SDHC lead to a significant change in SLC38A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SDHC and examine the expression of SLC38A1. Does perturbing SDHC lead to a significant change in SLC38A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47231
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIP7 is associated with a significant change in MTMR6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIP7 is associated with a significant change in MTMR6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31505
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBM33 is perturbed and the expression of RBM33 is measured. Determine whether RBM33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBM33 is perturbed and the expression of RBM33 is measured. Determine whether RBM33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41686
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARPC2 is perturbed and CENPW expression is quantified. Does this perturbation result in a significant change in CENPW expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARPC2 is perturbed and CENPW expression is quantified. Does this perturbation result in a significant change in CENPW expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2082
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PWP1 is perturbed and RRM2 expression is observed. Does this perturbation lead to a significant difference in RRM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PWP1 is perturbed and RRM2 expression is observed. Does this perturbation lead to a significant difference in RRM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40573
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NPLOC4 is perturbed and the expression of RND3 is measured. Does this perturbation cause a significant change in RND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NPLOC4 is perturbed and the expression of RND3 is measured. Does this perturbation cause a significant change in RND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32320
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CIAO1 is perturbed and MAP1B expression is measured. Determine whether MAP1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CIAO1 is perturbed and MAP1B expression is measured. Determine whether MAP1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7719
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MCEE and monitor XRCC2 expression. Decide whether this perturbation leads to a significant alteration in XRCC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MCEE and monitor XRCC2 expression. Decide whether this perturbation leads to a significant alteration in XRCC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24998
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZW10 is associated with a significant change in ZW10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZW10 is associated with a significant change in ZW10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62015
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBMX is associated with a significant change in KIF15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBMX is associated with a significant change in KIF15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41875
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PNISR is perturbed and the expression of NDFIP2 is measured. Does this perturbation cause a significant change in NDFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PNISR is perturbed and the expression of NDFIP2 is measured. Does this perturbation cause a significant change in NDFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35990
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOC2L and then measure expression of NOC2L. Does this perturbation cause a significant change in NOC2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOC2L and then measure expression of NOC2L. Does this perturbation cause a significant change in NOC2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31754
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and SCD expression is measured. Determine whether SCD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and SCD expression is measured. Determine whether SCD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20729
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NACA is perturbed and the expression of FAM83D is measured. Does this perturbation cause a significant change in FAM83D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NACA is perturbed and the expression of FAM83D is measured. Does this perturbation cause a significant change in FAM83D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29710
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSEN2 and examine the expression of NUPR1. Does perturbing TSEN2 lead to a significant change in NUPR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSEN2 and examine the expression of NUPR1. Does perturbing TSEN2 lead to a significant change in NUPR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55941
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PUF60 and examine the expression of GRN. Does perturbing PUF60 lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PUF60 and examine the expression of GRN. Does perturbing PUF60 lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40511
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP6C is perturbed and the expression of PPP6C is measured. Does this perturbation cause a significant change in PPP6C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP6C is perturbed and the expression of PPP6C is measured. Does this perturbation cause a significant change in PPP6C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38160
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ING3 is associated with a significant change in MT1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ING3 is associated with a significant change in MT1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21525
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELOF1 is perturbed and FAM20C expression is measured. Determine whether FAM20C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELOF1 is perturbed and FAM20C expression is measured. Determine whether FAM20C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15019
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBMX2 is perturbed and the expression of PRKDC is measured. Does this perturbation cause a significant change in PRKDC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBMX2 is perturbed and the expression of PRKDC is measured. Does this perturbation cause a significant change in PRKDC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41890
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZFC3H1 and examine the expression of SNHG10. Does perturbing ZFC3H1 lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZFC3H1 and examine the expression of SNHG10. Does perturbing ZFC3H1 lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61271
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STAG2 and then measure expression of STAT3. Does this perturbation cause a significant change in STAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STAG2 and then measure expression of STAT3. Does this perturbation cause a significant change in STAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51734
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMA6 and examine the expression of PLK1. Does perturbing PSMA6 lead to a significant change in PLK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMA6 and examine the expression of PLK1. Does perturbing PSMA6 lead to a significant change in PLK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39211
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTC1, does the expression profile of MT-ND2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTC1, does the expression profile of MT-ND2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56157
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GABPA is perturbed and DEPDC1B expression is observed. Does this perturbation lead to a significant difference in DEPDC1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GABPA is perturbed and DEPDC1B expression is observed. Does this perturbation lead to a significant difference in DEPDC1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17193
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C5orf30 and examine the expression of SMOX. Does perturbing C5orf30 lead to a significant change in SMOX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C5orf30 and examine the expression of SMOX. Does perturbing C5orf30 lead to a significant change in SMOX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4611
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAGOH is perturbed and the expression of MEG3 is measured. Determine whether MEG3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAGOH is perturbed and the expression of MEG3 is measured. Determine whether MEG3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24586
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb INO80B and monitor DTYMK expression. Decide whether this perturbation leads to a significant alteration in DTYMK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb INO80B and monitor DTYMK expression. Decide whether this perturbation leads to a significant alteration in DTYMK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21588
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POP1 is perturbed and NUSAP1 expression is measured. Determine whether NUSAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POP1 is perturbed and NUSAP1 expression is measured. Determine whether NUSAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37239
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRNP25 is associated with a significant change in SNRNP25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRNP25 is associated with a significant change in SNRNP25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49775
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5MD is perturbed and the expression of ATAD5 is measured. Does this perturbation cause a significant change in ATAD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5MD is perturbed and the expression of ATAD5 is measured. Does this perturbation cause a significant change in ATAD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2570
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TOMM22 is perturbed and TOMM22 expression is quantified. Does this perturbation result in a significant change in TOMM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TOMM22 is perturbed and TOMM22 expression is quantified. Does this perturbation result in a significant change in TOMM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54962
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TUBB is perturbed and TUBB3 expression is measured. Determine whether TUBB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TUBB is perturbed and TUBB3 expression is measured. Determine whether TUBB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56429
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOSC4 and examine the expression of SGO1. Does perturbing EXOSC4 lead to a significant change in SGO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOSC4 and examine the expression of SGO1. Does perturbing EXOSC4 lead to a significant change in SGO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16091
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ESF1 is perturbed and the expression of ESF1 is measured. Determine whether ESF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ESF1 is perturbed and the expression of ESF1 is measured. Determine whether ESF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15606
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAPC5, does the expression profile of SNAPC5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAPC5, does the expression profile of SNAPC5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49657
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC45, does the expression profile of DDI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC45, does the expression profile of DDI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6257
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IMPA2 and monitor FOXJ2 expression. Decide whether this perturbation leads to a significant alteration in FOXJ2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IMPA2 and monitor FOXJ2 expression. Decide whether this perturbation leads to a significant alteration in FOXJ2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21438
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEH1L is associated with a significant change in DNAJC9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEH1L is associated with a significant change in DNAJC9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47505
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED21, does the expression profile of SPC25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED21, does the expression profile of SPC25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25587
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBR5 and then measure expression of PDLIM2. Does this perturbation cause a significant change in PDLIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBR5 and then measure expression of PDLIM2. Does this perturbation cause a significant change in PDLIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57524
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MYBL2 and then measure expression of ZNRF1. Does this perturbation cause a significant change in ZNRF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MYBL2 and then measure expression of ZNRF1. Does this perturbation cause a significant change in ZNRF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29304
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOLC1 is perturbed and NOLC1 expression is observed. Does this perturbation lead to a significant difference in NOLC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOLC1 is perturbed and NOLC1 expression is observed. Does this perturbation lead to a significant difference in NOLC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32053
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MON1A is perturbed and RPL26L1 expression is observed. Does this perturbation lead to a significant difference in RPL26L1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MON1A is perturbed and RPL26L1 expression is observed. Does this perturbation lead to a significant difference in RPL26L1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26763
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCAPG2 is associated with a significant change in IQGAP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCAPG2 is associated with a significant change in IQGAP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30125
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CASC3 is perturbed and SNHG6 expression is quantified. Does this perturbation result in a significant change in SNHG6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CASC3 is perturbed and SNHG6 expression is quantified. Does this perturbation result in a significant change in SNHG6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5002
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SACM1L and then measure expression of MTFR2. Does this perturbation cause a significant change in MTFR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SACM1L and then measure expression of MTFR2. Does this perturbation cause a significant change in MTFR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46484
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOC2L and examine the expression of NOC2L. Does perturbing NOC2L lead to a significant change in NOC2L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOC2L and examine the expression of NOC2L. Does perturbing NOC2L lead to a significant change in NOC2L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31751
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC11 is perturbed and YIF1A expression is measured. Determine whether YIF1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC11 is perturbed and YIF1A expression is measured. Determine whether YIF1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55519
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC7 is perturbed and CDCA7 expression is observed. Does this perturbation lead to a significant difference in CDCA7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC7 is perturbed and CDCA7 expression is observed. Does this perturbation lead to a significant difference in CDCA7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15913
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PABPC1 and monitor PABPC1 expression. Decide whether this perturbation leads to a significant alteration in PABPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PABPC1 and monitor PABPC1 expression. Decide whether this perturbation leads to a significant alteration in PABPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33938
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MON1A and then measure expression of RPL26L1. Does this perturbation cause a significant change in RPL26L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MON1A and then measure expression of RPL26L1. Does this perturbation cause a significant change in RPL26L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26764
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSTF3 is perturbed and PHF11 expression is quantified. Does this perturbation result in a significant change in PHF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSTF3 is perturbed and PHF11 expression is quantified. Does this perturbation result in a significant change in PHF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10012
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NSL1 is perturbed and the expression of DUS4L is measured. Does this perturbation cause a significant change in DUS4L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NSL1 is perturbed and the expression of DUS4L is measured. Does this perturbation cause a significant change in DUS4L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32570
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DNTTIP2 and monitor DNTTIP2 expression. Decide whether this perturbation leads to a significant alteration in DNTTIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNTTIP2 and monitor DNTTIP2 expression. Decide whether this perturbation leads to a significant alteration in DNTTIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12818
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PDCD6IP and monitor LATS1 expression. Decide whether this perturbation leads to a significant alteration in LATS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDCD6IP and monitor LATS1 expression. Decide whether this perturbation leads to a significant alteration in LATS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34618
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MOK is perturbed and MSL3 expression is measured. Determine whether MSL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MOK is perturbed and MSL3 expression is measured. Determine whether MSL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26739
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS2 is perturbed and MT-ND3 expression is quantified. Does this perturbation result in a significant change in MT-ND3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS2 is perturbed and MT-ND3 expression is quantified. Does this perturbation result in a significant change in MT-ND3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52992
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, USP10 is perturbed and HMMR expression is quantified. Does this perturbation result in a significant change in HMMR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, USP10 is perturbed and HMMR expression is quantified. Does this perturbation result in a significant change in HMMR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58222
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRMT10C is perturbed and TRMT10C expression is measured. Determine whether TRMT10C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRMT10C is perturbed and TRMT10C expression is measured. Determine whether TRMT10C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55709
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HERC1 is associated with a significant change in HERC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HERC1 is associated with a significant change in HERC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19905
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCAPD2 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCAPD2 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30055
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNW1 and monitor SYF2 expression. Decide whether this perturbation leads to a significant alteration in SYF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNW1 and monitor SYF2 expression. Decide whether this perturbation leads to a significant alteration in SYF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50338
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RCOR1 is perturbed and the expression of MTMR4 is measured. Does this perturbation cause a significant change in MTMR4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RCOR1 is perturbed and the expression of MTMR4 is measured. Does this perturbation cause a significant change in MTMR4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42070
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR3 and examine the expression of NCAPG. Does perturbing WDR3 lead to a significant change in NCAPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR3 and examine the expression of NCAPG. Does perturbing WDR3 lead to a significant change in NCAPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59691
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF720 is perturbed and DBF4B expression is quantified. Does this perturbation result in a significant change in DBF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF720 is perturbed and DBF4B expression is quantified. Does this perturbation result in a significant change in DBF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61712
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS27, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS27, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45487
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRPF19 is perturbed and PRKDC expression is measured. Determine whether PRKDC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRPF19 is perturbed and PRKDC expression is measured. Determine whether PRKDC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38719
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb METTL3 and monitor GEMIN6 expression. Decide whether this perturbation leads to a significant alteration in GEMIN6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb METTL3 and monitor GEMIN6 expression. Decide whether this perturbation leads to a significant alteration in GEMIN6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26208
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CMTR2 is perturbed and the expression of SHCBP1 is measured. Does this perturbation cause a significant change in SHCBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CMTR2 is perturbed and the expression of SHCBP1 is measured. Does this perturbation cause a significant change in SHCBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8160
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPP4C is perturbed and NDUFA8 expression is quantified. Does this perturbation result in a significant change in NDUFA8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPP4C is perturbed and NDUFA8 expression is quantified. Does this perturbation result in a significant change in NDUFA8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38112
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF7 is perturbed and the expression of HEATR5A is measured. Does this perturbation cause a significant change in HEATR5A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF7 is perturbed and the expression of HEATR5A is measured. Does this perturbation cause a significant change in HEATR5A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52830
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TWNK, does the expression profile of MT-CO2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TWNK, does the expression profile of MT-CO2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56757
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, INO80 is perturbed and ASF1B expression is measured. Determine whether ASF1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, INO80 is perturbed and ASF1B expression is measured. Determine whether ASF1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21549
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELP6 is perturbed and the expression of PSAT1 is measured. Determine whether PSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELP6 is perturbed and the expression of PSAT1 is measured. Determine whether PSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15196
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM4 and examine the expression of MRPL10. Does perturbing PRDM4 lead to a significant change in MRPL10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM4 and examine the expression of MRPL10. Does perturbing PRDM4 lead to a significant change in MRPL10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38301
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDX51 and monitor ZBTB25 expression. Decide whether this perturbation leads to a significant alteration in ZBTB25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDX51 and monitor ZBTB25 expression. Decide whether this perturbation leads to a significant alteration in ZBTB25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11608
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCDC86 and monitor PRC1 expression. Decide whether this perturbation leads to a significant alteration in PRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCDC86 and monitor PRC1 expression. Decide whether this perturbation leads to a significant alteration in PRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5388
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNHIT1 is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNHIT1 is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61805
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED7, does the expression profile of IFT88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED7, does the expression profile of IFT88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25827
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPRC1 is perturbed and SNHG8 expression is measured. Determine whether SNHG8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPRC1 is perturbed and SNHG8 expression is measured. Determine whether SNHG8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38209
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PNKP, does the expression profile of FDXR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PNKP, does the expression profile of FDXR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36017
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS6 is perturbed and CENPK expression is quantified. Does this perturbation result in a significant change in CENPK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS6 is perturbed and CENPK expression is quantified. Does this perturbation result in a significant change in CENPK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8972
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NSA2 is perturbed and FKBP5 expression is observed. Does this perturbation lead to a significant difference in FKBP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NSA2 is perturbed and FKBP5 expression is observed. Does this perturbation lead to a significant difference in FKBP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32493
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2H1 and examine the expression of AIMP2. Does perturbing GTF2H1 lead to a significant change in AIMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2H1 and examine the expression of AIMP2. Does perturbing GTF2H1 lead to a significant change in AIMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18961
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCDC174 is perturbed and the expression of FAM111B is measured. Determine whether FAM111B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCDC174 is perturbed and the expression of FAM111B is measured. Determine whether FAM111B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5256
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRPF18, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRPF18, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38677
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR74 and then measure expression of CXCL8. Does this perturbation cause a significant change in CXCL8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR74 and then measure expression of CXCL8. Does this perturbation cause a significant change in CXCL8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60034
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPS30 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPS30 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28658
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL7 is associated with a significant change in RPL7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL7 is associated with a significant change in RPL7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44505
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF5 is perturbed and the expression of ESCO2 is measured. Does this perturbation cause a significant change in ESCO2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF5 is perturbed and the expression of ESCO2 is measured. Does this perturbation cause a significant change in ESCO2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30670
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2F2 and then measure expression of MCM10. Does this perturbation cause a significant change in MCM10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2F2 and then measure expression of MCM10. Does this perturbation cause a significant change in MCM10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18934
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSNK2B and examine the expression of CSNK2B. Does perturbing CSNK2B lead to a significant change in CSNK2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSNK2B and examine the expression of CSNK2B. Does perturbing CSNK2B lead to a significant change in CSNK2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9931
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF23 is perturbed and EIF2B1 expression is measured. Determine whether EIF2B1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF23 is perturbed and EIF2B1 expression is measured. Determine whether EIF2B1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23149
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD13 is perturbed and the expression of MAP1A is measured. Determine whether MAP1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD13 is perturbed and the expression of MAP1A is measured. Determine whether MAP1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39756
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PMF1 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PMF1 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35909
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARPC4 is perturbed and the expression of FIGN is measured. Determine whether FIGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARPC4 is perturbed and the expression of FIGN is measured. Determine whether FIGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2156
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP214, does the expression profile of CCDC80 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP214, does the expression profile of CCDC80 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33187
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5MD and examine the expression of MYBL2. Does perturbing ATP5MD lead to a significant change in MYBL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5MD and examine the expression of MYBL2. Does perturbing ATP5MD lead to a significant change in MYBL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2551
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS26 is perturbed and the expression of MRPS26 is measured. Does this perturbation cause a significant change in MRPS26 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS26 is perturbed and the expression of MRPS26 is measured. Does this perturbation cause a significant change in MRPS26 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28560
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS26 is associated with a significant change in CDC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS26 is associated with a significant change in CDC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45475
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYF2 is perturbed and the expression of ZBED3 is measured. Does this perturbation cause a significant change in ZBED3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYF2 is perturbed and the expression of ZBED3 is measured. Does this perturbation cause a significant change in ZBED3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52330
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4A1 is associated with a significant change in UTP25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4A1 is associated with a significant change in UTP25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14635
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL36 is perturbed and the expression of MT-ATP8 is measured. Does this perturbation cause a significant change in MT-ATP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL36 is perturbed and the expression of MT-ATP8 is measured. Does this perturbation cause a significant change in MT-ATP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27620
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRD8 is associated with a significant change in GPR180 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRD8 is associated with a significant change in GPR180 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3955
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL20 and examine the expression of FAAP20. Does perturbing MRPL20 lead to a significant change in FAAP20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL20 and examine the expression of FAAP20. Does perturbing MRPL20 lead to a significant change in FAAP20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27251
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS15 and examine the expression of TMSB15A. Does perturbing RPS15 lead to a significant change in TMSB15A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS15 and examine the expression of TMSB15A. Does perturbing RPS15 lead to a significant change in TMSB15A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45091
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of DDIT3. Does perturbing HYOU1 lead to a significant change in DDIT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of DDIT3. Does perturbing HYOU1 lead to a significant change in DDIT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21091
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP5MF and monitor METTL5 expression. Decide whether this perturbation leads to a significant alteration in METTL5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP5MF and monitor METTL5 expression. Decide whether this perturbation leads to a significant alteration in METTL5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2628
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR3E is associated with a significant change in HAUS8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR3E is associated with a significant change in HAUS8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37095
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IK is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IK is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21326
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIOS is perturbed and NUDT2 expression is quantified. Does this perturbation result in a significant change in NUDT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIOS is perturbed and NUDT2 expression is quantified. Does this perturbation result in a significant change in NUDT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26342
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TEX10 and then measure expression of PRIM1. Does this perturbation cause a significant change in PRIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TEX10 and then measure expression of PRIM1. Does this perturbation cause a significant change in PRIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53544
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ACTB and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ACTB and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":524
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EEF2 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EEF2 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13825
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPZ is perturbed and the expression of RAD51 is measured. Does this perturbation cause a significant change in RAD51 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPZ is perturbed and the expression of RAD51 is measured. Does this perturbation cause a significant change in RAD51 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6670
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM3AP, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM3AP, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25157
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TEFM is perturbed and the expression of MT-ND4L is measured. Determine whether MT-ND4L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TEFM is perturbed and the expression of MT-ND4L is measured. Determine whether MT-ND4L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53396
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELP5 is perturbed and the expression of PSAT1 is measured. Determine whether PSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELP5 is perturbed and the expression of PSAT1 is measured. Determine whether PSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15156
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RABGGTB is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RABGGTB is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40893
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAE1, does the expression profile of CDCA5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAE1, does the expression profile of CDCA5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41187
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL9 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL9 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28098
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SFPQ and monitor POLQ expression. Decide whether this perturbation leads to a significant alteration in POLQ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SFPQ and monitor POLQ expression. Decide whether this perturbation leads to a significant alteration in POLQ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48128
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in TFCP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in TFCP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8745
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPH1 is perturbed and EEF1B2 expression is measured. Determine whether EEF1B2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPH1 is perturbed and EEF1B2 expression is measured. Determine whether EEF1B2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20459
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPTF is perturbed and BPTF expression is quantified. Does this perturbation result in a significant change in BPTF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPTF is perturbed and BPTF expression is quantified. Does this perturbation result in a significant change in BPTF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3782
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR1B and then measure expression of SYNE2. Does this perturbation cause a significant change in SYNE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR1B and then measure expression of SYNE2. Does this perturbation cause a significant change in SYNE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36494
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHMP6 is perturbed and the expression of CXCL8 is measured. Determine whether CXCL8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHMP6 is perturbed and the expression of CXCL8 is measured. Determine whether CXCL8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7566
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMA1, does the expression profile of ATAD5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMA1, does the expression profile of ATAD5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39117
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSFM is perturbed and the expression of DKK1 is measured. Determine whether DKK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSFM is perturbed and the expression of DKK1 is measured. Determine whether DKK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56026
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERCC2 is associated with a significant change in ACTA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERCC2 is associated with a significant change in ACTA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15515
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS21 is perturbed and NUSAP1 expression is measured. Determine whether NUSAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS21 is perturbed and NUSAP1 expression is measured. Determine whether NUSAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45359
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PAXBP1 is perturbed and the expression of GAS5 is measured. Determine whether GAS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PAXBP1 is perturbed and the expression of GAS5 is measured. Determine whether GAS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34226
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARPC2 is perturbed and the expression of ARPC2 is measured. Does this perturbation cause a significant change in ARPC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARPC2 is perturbed and the expression of ARPC2 is measured. Does this perturbation cause a significant change in ARPC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2070
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2C and examine the expression of CASP8AP2. Does perturbing POLR2C lead to a significant change in CASP8AP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2C and examine the expression of CASP8AP2. Does perturbing POLR2C lead to a significant change in CASP8AP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36661
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GPKOW is perturbed and MMAB expression is observed. Does this perturbation lead to a significant difference in MMAB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GPKOW is perturbed and MMAB expression is observed. Does this perturbation lead to a significant difference in MMAB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18413
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of DDOST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of DDOST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11047
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MDN1 is perturbed and the expression of INPP5F is measured. Does this perturbation cause a significant change in INPP5F expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MDN1 is perturbed and the expression of INPP5F is measured. Does this perturbation cause a significant change in INPP5F expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25360
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BTF3L4 and examine the expression of BTF3L4. Does perturbing BTF3L4 lead to a significant change in BTF3L4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BTF3L4 and examine the expression of BTF3L4. Does perturbing BTF3L4 lead to a significant change in BTF3L4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4141
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of THAP11 is associated with a significant change in MRPL54 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of THAP11 is associated with a significant change in MRPL54 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53805
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PNISR is associated with a significant change in PNISR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PNISR is associated with a significant change in PNISR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35975
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DESI1 is perturbed and SLC37A4 expression is observed. Does this perturbation lead to a significant difference in SLC37A4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DESI1 is perturbed and SLC37A4 expression is observed. Does this perturbation lead to a significant difference in SLC37A4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11873
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBCC, does the expression profile of PRKD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBCC, does the expression profile of PRKD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53157
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VPS54 is associated with a significant change in PAPPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VPS54 is associated with a significant change in PAPPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59265
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TUBGCP3 is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TUBGCP3 is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56550
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SSBP3 is perturbed and PTGES2 expression is measured. Determine whether PTGES2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SSBP3 is perturbed and PTGES2 expression is measured. Determine whether PTGES2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51659
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GCLC is perturbed and the expression of NQO1 is measured. Does this perturbation cause a significant change in NQO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GCLC is perturbed and the expression of NQO1 is measured. Does this perturbation cause a significant change in NQO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17430
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UPF2 is perturbed and the expression of SNHG7 is measured. Determine whether SNHG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UPF2 is perturbed and the expression of SNHG7 is measured. Determine whether SNHG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57836
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUB3 and then measure expression of BUB3. Does this perturbation cause a significant change in BUB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUB3 and then measure expression of BUB3. Does this perturbation cause a significant change in BUB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4254
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CIAPIN1 and monitor RPL22L1 expression. Decide whether this perturbation leads to a significant alteration in RPL22L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CIAPIN1 and monitor RPL22L1 expression. Decide whether this perturbation leads to a significant alteration in RPL22L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7768
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NDUFB10 and monitor HSBP1 expression. Decide whether this perturbation leads to a significant alteration in HSBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NDUFB10 and monitor HSBP1 expression. Decide whether this perturbation leads to a significant alteration in HSBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30748
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS17 and examine the expression of MRPS17. Does perturbing MRPS17 lead to a significant change in MRPS17 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS17 and examine the expression of MRPS17. Does perturbing MRPS17 lead to a significant change in MRPS17 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28261
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5ME, does the expression profile of ATP5ME indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5ME, does the expression profile of ATP5ME indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2587
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SMARCE1 and monitor SMARCE1 expression. Decide whether this perturbation leads to a significant alteration in SMARCE1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SMARCE1 and monitor SMARCE1 expression. Decide whether this perturbation leads to a significant alteration in SMARCE1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49058
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SDHC is perturbed and SLC38A1 expression is quantified. Does this perturbation result in a significant change in SLC38A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SDHC is perturbed and SLC38A1 expression is quantified. Does this perturbation result in a significant change in SLC38A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47232
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EPRS, does the expression profile of EPRS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EPRS, does the expression profile of EPRS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15477
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PELP1 and examine the expression of CDKN1A. Does perturbing PELP1 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PELP1 and examine the expression of CDKN1A. Does perturbing PELP1 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34821
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PET117 is perturbed and RPL22L1 expression is measured. Determine whether RPL22L1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PET117 is perturbed and RPL22L1 expression is measured. Determine whether RPL22L1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34879
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ORC6 and monitor POLD1 expression. Decide whether this perturbation leads to a significant alteration in POLD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ORC6 and monitor POLD1 expression. Decide whether this perturbation leads to a significant alteration in POLD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33788
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM39 and examine the expression of STAMBPL1. Does perturbing RBM39 lead to a significant change in STAMBPL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM39 and examine the expression of STAMBPL1. Does perturbing RBM39 lead to a significant change in STAMBPL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41701
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA0586 and examine the expression of KIAA0586. Does perturbing KIAA0586 lead to a significant change in KIAA0586 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA0586 and examine the expression of KIAA0586. Does perturbing KIAA0586 lead to a significant change in KIAA0586 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22981
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ACTR1A and then measure expression of ACTR1A. Does this perturbation cause a significant change in ACTR1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ACTR1A and then measure expression of ACTR1A. Does this perturbation cause a significant change in ACTR1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":614
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB8 is perturbed and the expression of TGM2 is measured. Does this perturbation cause a significant change in TGM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB8 is perturbed and the expression of TGM2 is measured. Does this perturbation cause a significant change in TGM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30880
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4G1 is associated with a significant change in TM4SF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4G1 is associated with a significant change in TM4SF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14745
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISCU is associated with a significant change in CPT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISCU is associated with a significant change in CPT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22305
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PMF1 is perturbed and the expression of PLAU is measured. Determine whether PLAU shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PMF1 is perturbed and the expression of PLAU is measured. Determine whether PLAU shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35896
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DOHH is perturbed and DOHH expression is observed. Does this perturbation lead to a significant difference in DOHH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DOHH is perturbed and DOHH expression is observed. Does this perturbation lead to a significant difference in DOHH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12843
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBM42 is perturbed and the expression of HIST1H1B is measured. Determine whether HIST1H1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBM42 is perturbed and the expression of HIST1H1B is measured. Determine whether HIST1H1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41766
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLP1 is perturbed and TCF19 expression is quantified. Does this perturbation result in a significant change in TCF19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLP1 is perturbed and TCF19 expression is quantified. Does this perturbation result in a significant change in TCF19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7962
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDC42 and examine the expression of CDC42. Does perturbing CDC42 lead to a significant change in CDC42 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDC42 and examine the expression of CDC42. Does perturbing CDC42 lead to a significant change in CDC42 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6221
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCMF1 is perturbed and CEP126 expression is measured. Determine whether CEP126 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCMF1 is perturbed and CEP126 expression is measured. Determine whether CEP126 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22799
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2B is associated with a significant change in PEX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2B is associated with a significant change in PEX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36655
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKAP5 is associated with a significant change in PCSK1N expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKAP5 is associated with a significant change in PCSK1N expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7815
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TEN1 is perturbed and TEN1 expression is observed. Does this perturbation lead to a significant difference in TEN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TEN1 is perturbed and TEN1 expression is observed. Does this perturbation lead to a significant difference in TEN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53443
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF131, does the expression profile of KNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF131, does the expression profile of KNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61437
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL23A is perturbed and the expression of ATAD5 is measured. Does this perturbation cause a significant change in ATAD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL23A is perturbed and the expression of ATAD5 is measured. Does this perturbation cause a significant change in ATAD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43710
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TYK2 and examine the expression of AIMP2. Does perturbing TYK2 lead to a significant change in AIMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TYK2 and examine the expression of AIMP2. Does perturbing TYK2 lead to a significant change in AIMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56901
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSTK is associated with a significant change in PSTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSTK is associated with a significant change in PSTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40205
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ORC6 and then measure expression of C1QL1. Does this perturbation cause a significant change in C1QL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ORC6 and then measure expression of C1QL1. Does this perturbation cause a significant change in C1QL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33794
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NKAPD1, does the expression profile of SNHG19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NKAPD1, does the expression profile of SNHG19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31617
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IPO13 is perturbed and the expression of MCM6 is measured. Determine whether MCM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IPO13 is perturbed and the expression of MCM6 is measured. Determine whether MCM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22146
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RAB4A and examine the expression of GANAB. Does perturbing RAB4A lead to a significant change in GANAB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RAB4A and examine the expression of GANAB. Does perturbing RAB4A lead to a significant change in GANAB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40781
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGD and examine the expression of PGD. Does perturbing PGD lead to a significant change in PGD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGD and examine the expression of PGD. Does perturbing PGD lead to a significant change in PGD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35191
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSG1 is perturbed and the expression of MKI67 is measured. Does this perturbation cause a significant change in MKI67 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSG1 is perturbed and the expression of MKI67 is measured. Does this perturbation cause a significant change in MKI67 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24100
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD1, does the expression profile of CCDC90B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD1, does the expression profile of CCDC90B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31017
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MT2A, does the expression profile of MT2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MT2A, does the expression profile of MT2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29047
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBM28 is associated with a significant change in MYBL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBM28 is associated with a significant change in MYBL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41645
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS18A is perturbed and MTRNR2L12 expression is observed. Does this perturbation lead to a significant difference in MTRNR2L12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS18A is perturbed and MTRNR2L12 expression is observed. Does this perturbation lead to a significant difference in MTRNR2L12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28293
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDCD6IP and then measure expression of PDCD6IP. Does this perturbation cause a significant change in PDCD6IP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDCD6IP and then measure expression of PDCD6IP. Does this perturbation cause a significant change in PDCD6IP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34594
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS41 and then measure expression of VPS41. Does this perturbation cause a significant change in VPS41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS41 and then measure expression of VPS41. Does this perturbation cause a significant change in VPS41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59204
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAD51D is perturbed and the expression of TMEM158 is measured. Determine whether TMEM158 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAD51D is perturbed and the expression of TMEM158 is measured. Determine whether TMEM158 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41156
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPTF and then measure expression of THY1. Does this perturbation cause a significant change in THY1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPTF and then measure expression of THY1. Does this perturbation cause a significant change in THY1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3794
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GLMN and monitor RNF20 expression. Decide whether this perturbation leads to a significant alteration in RNF20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GLMN and monitor RNF20 expression. Decide whether this perturbation leads to a significant alteration in RNF20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18028
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL12, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL12, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43397
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XPO5 and then measure expression of XPO5. Does this perturbation cause a significant change in XPO5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XPO5 and then measure expression of XPO5. Does this perturbation cause a significant change in XPO5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60404
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRCC2, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRCC2, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60477
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNRNPK, does the expression profile of PHPT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNRNPK, does the expression profile of PHPT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20487
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF11 is perturbed and ARHGEF28 expression is measured. Determine whether ARHGEF28 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF11 is perturbed and ARHGEF28 expression is measured. Determine whether ARHGEF28 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23049
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CACNB3 and then measure expression of CACNB3. Does this perturbation cause a significant change in CACNB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CACNB3 and then measure expression of CACNB3. Does this perturbation cause a significant change in CACNB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4774
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FGFR1OP is perturbed and the expression of PSMB10 is measured. Does this perturbation cause a significant change in PSMB10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FGFR1OP is perturbed and the expression of PSMB10 is measured. Does this perturbation cause a significant change in PSMB10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16930
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in DDIT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in DDIT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4955
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NAE1 is associated with a significant change in SLC7A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NAE1 is associated with a significant change in SLC7A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29755
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TXN and monitor ZMAT3 expression. Decide whether this perturbation leads to a significant alteration in ZMAT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TXN and monitor ZMAT3 expression. Decide whether this perturbation leads to a significant alteration in ZMAT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56818
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RMI1 is associated with a significant change in SPATA7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RMI1 is associated with a significant change in SPATA7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42515
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ESF1 and then measure expression of ESF1. Does this perturbation cause a significant change in ESF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ESF1 and then measure expression of ESF1. Does this perturbation cause a significant change in ESF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15604
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP153 is perturbed and the expression of ZIM3 is measured. Determine whether ZIM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP153 is perturbed and the expression of ZIM3 is measured. Determine whether ZIM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33066
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VPS18, does the expression profile of FKBP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VPS18, does the expression profile of FKBP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59007
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL46, does the expression profile of VAMP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL46, does the expression profile of VAMP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27917
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GART and examine the expression of PIGQ. Does perturbing GART lead to a significant change in PIGQ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GART and examine the expression of PIGQ. Does perturbing GART lead to a significant change in PIGQ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17371
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TADA3 and examine the expression of TADA3. Does perturbing TADA3 lead to a significant change in TADA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TADA3 and examine the expression of TADA3. Does perturbing TADA3 lead to a significant change in TADA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52521
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR3K, does the expression profile of KLHL7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR3K, does the expression profile of KLHL7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37177
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COX5B is perturbed and COX5B expression is quantified. Does this perturbation result in a significant change in COX5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COX5B is perturbed and COX5B expression is quantified. Does this perturbation result in a significant change in COX5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9332
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GET1 is perturbed and FLOT1 expression is quantified. Does this perturbation result in a significant change in FLOT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GET1 is perturbed and FLOT1 expression is quantified. Does this perturbation result in a significant change in FLOT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17612
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD7 is perturbed and the expression of TRIM7 is measured. Does this perturbation cause a significant change in TRIM7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD7 is perturbed and the expression of TRIM7 is measured. Does this perturbation cause a significant change in TRIM7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39950
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS13 and examine the expression of INTS13. Does perturbing INTS13 lead to a significant change in INTS13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS13 and examine the expression of INTS13. Does perturbing INTS13 lead to a significant change in INTS13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21841
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OGFOD1 is perturbed and SRP9 expression is measured. Determine whether SRP9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OGFOD1 is perturbed and SRP9 expression is measured. Determine whether SRP9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33559
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED6 is perturbed and the expression of CA9 is measured. Determine whether CA9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED6 is perturbed and the expression of CA9 is measured. Determine whether CA9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25786
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DYNLL2 is associated with a significant change in QDPR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DYNLL2 is associated with a significant change in QDPR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13475
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZMAT2 and monitor ZMAT2 expression. Decide whether this perturbation leads to a significant alteration in ZMAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZMAT2 and monitor ZMAT2 expression. Decide whether this perturbation leads to a significant alteration in ZMAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61338
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51797
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2N and examine the expression of FXYD5. Does perturbing UBE2N lead to a significant change in FXYD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2N and examine the expression of FXYD5. Does perturbing UBE2N lead to a significant change in FXYD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57341
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NPLOC4 is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NPLOC4 is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32330
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB10 and then measure expression of TMSB10. Does this perturbation cause a significant change in TMSB10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB10 and then measure expression of TMSB10. Does this perturbation cause a significant change in TMSB10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54784
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SON is associated with a significant change in DDIT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SON is associated with a significant change in DDIT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50435
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCAS2 is perturbed and DGAT1 expression is quantified. Does this perturbation result in a significant change in DGAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCAS2 is perturbed and DGAT1 expression is quantified. Does this perturbation result in a significant change in DGAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3392
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RAN and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RAN and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41248
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL3 and then measure expression of MRPL3. Does this perturbation cause a significant change in MRPL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL3 and then measure expression of MRPL3. Does this perturbation cause a significant change in MRPL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27454
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCMF1, does the expression profile of SNX21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCMF1, does the expression profile of SNX21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22787
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR3B is perturbed and TARBP1 expression is quantified. Does this perturbation result in a significant change in TARBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR3B is perturbed and TARBP1 expression is quantified. Does this perturbation result in a significant change in TARBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37002
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS18B and examine the expression of ARL4D. Does perturbing MRPS18B lead to a significant change in ARL4D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS18B and examine the expression of ARL4D. Does perturbing MRPS18B lead to a significant change in ARL4D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28321
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SON is perturbed and DDIT3 expression is measured. Determine whether DDIT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SON is perturbed and DDIT3 expression is measured. Determine whether DDIT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50439
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL28 and monitor MT-ND2 expression. Decide whether this perturbation leads to a significant alteration in MT-ND2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL28 and monitor MT-ND2 expression. Decide whether this perturbation leads to a significant alteration in MT-ND2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27448
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRPG and then measure expression of SPAG5. Does this perturbation cause a significant change in SPAG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRPG and then measure expression of SPAG5. Does this perturbation cause a significant change in SPAG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50234
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPIE and monitor IMPA2 expression. Decide whether this perturbation leads to a significant alteration in IMPA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPIE and monitor IMPA2 expression. Decide whether this perturbation leads to a significant alteration in IMPA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37528
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23B and monitor MT-ATP6 expression. Decide whether this perturbation leads to a significant alteration in MT-ATP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23B and monitor MT-ATP6 expression. Decide whether this perturbation leads to a significant alteration in MT-ATP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54238
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEN1 is perturbed and the expression of FKBP7 is measured. Determine whether FKBP7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEN1 is perturbed and the expression of FKBP7 is measured. Determine whether FKBP7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16906
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DCTN6 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DCTN6 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10968
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3M is perturbed and EIF3M expression is observed. Does this perturbation lead to a significant difference in EIF3M expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3M is perturbed and EIF3M expression is observed. Does this perturbation lead to a significant difference in EIF3M expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14583
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NHP2 and examine the expression of NHP2. Does perturbing NHP2 lead to a significant change in NHP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NHP2 and examine the expression of NHP2. Does perturbing NHP2 lead to a significant change in NHP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31451
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LAMB1 is perturbed and the expression of CLSPN is measured. Determine whether CLSPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LAMB1 is perturbed and the expression of CLSPN is measured. Determine whether CLSPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23546
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HMGCR, does the expression profile of INTS7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HMGCR, does the expression profile of INTS7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20267
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCAPH2 is perturbed and the expression of PCLAF is measured. Determine whether PCLAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCAPH2 is perturbed and the expression of PCLAF is measured. Determine whether PCLAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30206
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NRBP1 is perturbed and NRBP1 expression is observed. Does this perturbation lead to a significant difference in NRBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NRBP1 is perturbed and NRBP1 expression is observed. Does this perturbation lead to a significant difference in NRBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32433
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POGLUT3 and monitor POGLUT3 expression. Decide whether this perturbation leads to a significant alteration in POGLUT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POGLUT3 and monitor POGLUT3 expression. Decide whether this perturbation leads to a significant alteration in POGLUT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36128
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRRM1 is associated with a significant change in SRRM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRRM1 is associated with a significant change in SRRM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51275
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOD1 is perturbed and CDK1 expression is quantified. Does this perturbation result in a significant change in CDK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOD1 is perturbed and CDK1 expression is quantified. Does this perturbation result in a significant change in CDK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50372
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS25 is perturbed and GLUL expression is observed. Does this perturbation lead to a significant difference in GLUL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS25 is perturbed and GLUL expression is observed. Does this perturbation lead to a significant difference in GLUL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45423
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PIK3R4 is perturbed and the expression of RTTN is measured. Determine whether RTTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PIK3R4 is perturbed and the expression of RTTN is measured. Determine whether RTTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35666
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EEF1A1 is perturbed and ZNF680 expression is quantified. Does this perturbation result in a significant change in ZNF680 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EEF1A1 is perturbed and ZNF680 expression is quantified. Does this perturbation result in a significant change in ZNF680 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13722
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHCTF1 is perturbed and LARP6 expression is quantified. Does this perturbation result in a significant change in LARP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHCTF1 is perturbed and LARP6 expression is quantified. Does this perturbation result in a significant change in LARP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":982
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDC16 and examine the expression of CDKN1A. Does perturbing CDC16 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDC16 and examine the expression of CDKN1A. Does perturbing CDC16 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6001
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS24 is perturbed and MRPS24 expression is observed. Does this perturbation lead to a significant difference in MRPS24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS24 is perturbed and MRPS24 expression is observed. Does this perturbation lead to a significant difference in MRPS24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28503
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELP6 is perturbed and PSAT1 expression is quantified. Does this perturbation result in a significant change in PSAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELP6 is perturbed and PSAT1 expression is quantified. Does this perturbation result in a significant change in PSAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15192
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NISCH and then measure expression of IREB2. Does this perturbation cause a significant change in IREB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NISCH and then measure expression of IREB2. Does this perturbation cause a significant change in IREB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31554
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UPF2 is perturbed and the expression of SNHG5 is measured. Determine whether SNHG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UPF2 is perturbed and the expression of SNHG5 is measured. Determine whether SNHG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57826
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TNRC6A, does the expression profile of CTSD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TNRC6A, does the expression profile of CTSD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54897
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZFR is perturbed and ZFR expression is observed. Does this perturbation lead to a significant difference in ZFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZFR is perturbed and ZFR expression is observed. Does this perturbation lead to a significant difference in ZFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61293
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SUPT16H is perturbed and FAM111B expression is quantified. Does this perturbation result in a significant change in FAM111B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SUPT16H is perturbed and FAM111B expression is quantified. Does this perturbation result in a significant change in FAM111B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52122
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RINT1 is perturbed and the expression of DDIT3 is measured. Does this perturbation cause a significant change in DDIT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RINT1 is perturbed and the expression of DDIT3 is measured. Does this perturbation cause a significant change in DDIT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42420
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARDBP is perturbed and PFKP expression is measured. Determine whether PFKP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARDBP is perturbed and PFKP expression is measured. Determine whether PFKP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52939
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNL3 and examine the expression of CDC25B. Does perturbing GNL3 lead to a significant change in CDC25B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNL3 and examine the expression of CDC25B. Does perturbing GNL3 lead to a significant change in CDC25B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18191
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GINS2, does the expression profile of GINS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GINS2, does the expression profile of GINS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17837
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1B is perturbed and HGH1 expression is measured. Determine whether HGH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1B is perturbed and HGH1 expression is measured. Determine whether HGH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7189
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL16 is perturbed and MT-ND3 expression is observed. Does this perturbation lead to a significant difference in MT-ND3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL16 is perturbed and MT-ND3 expression is observed. Does this perturbation lead to a significant difference in MT-ND3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27113
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTOR is perturbed and the expression of RRM2 is measured. Determine whether RRM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTOR is perturbed and the expression of RRM2 is measured. Determine whether RRM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29146
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARGLU1 and then measure expression of HCFC1R1. Does this perturbation cause a significant change in HCFC1R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARGLU1 and then measure expression of HCFC1R1. Does this perturbation cause a significant change in HCFC1R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1844
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TCERG1 and then measure expression of SMYD4. Does this perturbation cause a significant change in SMYD4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TCERG1 and then measure expression of SMYD4. Does this perturbation cause a significant change in SMYD4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53274
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5MF is perturbed and METTL5 expression is quantified. Does this perturbation result in a significant change in METTL5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5MF is perturbed and METTL5 expression is quantified. Does this perturbation result in a significant change in METTL5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2622
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3L, does the expression profile of SNHG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3L, does the expression profile of SNHG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14567
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF7 is perturbed and the expression of SLC43A3 is measured. Determine whether SLC43A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF7 is perturbed and the expression of SLC43A3 is measured. Determine whether SLC43A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23256
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SDHD is perturbed and DENND1A expression is quantified. Does this perturbation result in a significant change in DENND1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SDHD is perturbed and DENND1A expression is quantified. Does this perturbation result in a significant change in DENND1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47252
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM4 and examine the expression of RBM4. Does perturbing RBM4 lead to a significant change in RBM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM4 and examine the expression of RBM4. Does perturbing RBM4 lead to a significant change in RBM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41741
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CS is perturbed and the expression of CS is measured. Does this perturbation cause a significant change in CS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CS is perturbed and the expression of CS is measured. Does this perturbation cause a significant change in CS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9810
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TOP1, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TOP1, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55077
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL41 and then measure expression of GSTM3. Does this perturbation cause a significant change in GSTM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL41 and then measure expression of GSTM3. Does this perturbation cause a significant change in GSTM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44414
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPH1 is associated with a significant change in RAD51AP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPH1 is associated with a significant change in RAD51AP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20985
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MED14 is perturbed and the expression of ZNF367 is measured. Does this perturbation cause a significant change in ZNF367 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MED14 is perturbed and the expression of ZNF367 is measured. Does this perturbation cause a significant change in ZNF367 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25470
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELL is perturbed and NASP expression is quantified. Does this perturbation result in a significant change in NASP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELL is perturbed and NASP expression is quantified. Does this perturbation result in a significant change in NASP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14962
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMC3 is perturbed and the expression of MYO19 is measured. Determine whether MYO19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMC3 is perturbed and the expression of MYO19 is measured. Determine whether MYO19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39546
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ESF1 is perturbed and the expression of SUGCT is measured. Does this perturbation cause a significant change in SUGCT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ESF1 is perturbed and the expression of SUGCT is measured. Does this perturbation cause a significant change in SUGCT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15610
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KPNA6 is perturbed and ECHS1 expression is quantified. Does this perturbation result in a significant change in ECHS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KPNA6 is perturbed and ECHS1 expression is quantified. Does this perturbation result in a significant change in ECHS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23292
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPA3, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPA3, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43067
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNOT9 is perturbed and CEP295 expression is observed. Does this perturbation lead to a significant difference in CEP295 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNOT9 is perturbed and CEP295 expression is observed. Does this perturbation lead to a significant difference in CEP295 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8403
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, METTL14 is perturbed and the expression of ORAI1 is measured. Does this perturbation cause a significant change in ORAI1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, METTL14 is perturbed and the expression of ORAI1 is measured. Does this perturbation cause a significant change in ORAI1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26060
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NAA25 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NAA25 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29558
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS34 is perturbed and the expression of TMEM192 is measured. Does this perturbation cause a significant change in TMEM192 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS34 is perturbed and the expression of TMEM192 is measured. Does this perturbation cause a significant change in TMEM192 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28760
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ITGB1BP1 is perturbed and the expression of TOE1 is measured. Determine whether TOE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ITGB1BP1 is perturbed and the expression of TOE1 is measured. Determine whether TOE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22436
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LETM1 and examine the expression of LETM1. Does perturbing LETM1 lead to a significant change in LETM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LETM1 and examine the expression of LETM1. Does perturbing LETM1 lead to a significant change in LETM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23871
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which METAP2 is perturbed and DCTPP1 expression is observed. Does this perturbation lead to a significant difference in DCTPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which METAP2 is perturbed and DCTPP1 expression is observed. Does this perturbation lead to a significant difference in DCTPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25983
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and DAD1 expression is observed. Does this perturbation lead to a significant difference in DAD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and DAD1 expression is observed. Does this perturbation lead to a significant difference in DAD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10593
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CTNNBL1 is perturbed and the expression of FBXO32 is measured. Does this perturbation cause a significant change in FBXO32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CTNNBL1 is perturbed and the expression of FBXO32 is measured. Does this perturbation cause a significant change in FBXO32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10120
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NDUFS3 and examine the expression of IGFBP5. Does perturbing NDUFS3 lead to a significant change in IGFBP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NDUFS3 and examine the expression of IGFBP5. Does perturbing NDUFS3 lead to a significant change in IGFBP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30921
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLASRP is perturbed and HLA-B expression is quantified. Does this perturbation result in a significant change in HLA-B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLASRP is perturbed and HLA-B expression is quantified. Does this perturbation result in a significant change in HLA-B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7832
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GON4L is perturbed and the expression of GON4L is measured. Determine whether GON4L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GON4L is perturbed and the expression of GON4L is measured. Determine whether GON4L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18356
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CINP is perturbed and the expression of ERCC6L is measured. Determine whether ERCC6L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CINP is perturbed and the expression of ERCC6L is measured. Determine whether ERCC6L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7796
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL7 and examine the expression of PCLAF. Does perturbing RPL7 lead to a significant change in PCLAF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL7 and examine the expression of PCLAF. Does perturbing RPL7 lead to a significant change in PCLAF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44491
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBE2N is perturbed and the expression of FXYD5 is measured. Determine whether FXYD5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBE2N is perturbed and the expression of FXYD5 is measured. Determine whether FXYD5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57346
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TKT and monitor TKT expression. Decide whether this perturbation leads to a significant alteration in TKT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TKT and monitor TKT expression. Decide whether this perturbation leads to a significant alteration in TKT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54398
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DBF4 and monitor FBXO33 expression. Decide whether this perturbation leads to a significant alteration in FBXO33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DBF4 and monitor FBXO33 expression. Decide whether this perturbation leads to a significant alteration in FBXO33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10738
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAT2A, does the expression profile of CHRAC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAT2A, does the expression profile of CHRAC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24777
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS19BP1 is perturbed and SYNE2 expression is observed. Does this perturbation lead to a significant difference in SYNE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS19BP1 is perturbed and SYNE2 expression is observed. Does this perturbation lead to a significant difference in SYNE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45243
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HTATSF1 and monitor ZNHIT1 expression. Decide whether this perturbation leads to a significant alteration in ZNHIT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HTATSF1 and monitor ZNHIT1 expression. Decide whether this perturbation leads to a significant alteration in ZNHIT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21018
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNRD1 is associated with a significant change in PKMYT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNRD1 is associated with a significant change in PKMYT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61945
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ADRM1 and monitor ADRM1 expression. Decide whether this perturbation leads to a significant alteration in ADRM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ADRM1 and monitor ADRM1 expression. Decide whether this perturbation leads to a significant alteration in ADRM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":848
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MBD3 is perturbed and RPL26L1 expression is quantified. Does this perturbation result in a significant change in RPL26L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MBD3 is perturbed and RPL26L1 expression is quantified. Does this perturbation result in a significant change in RPL26L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24852
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UXS1 is perturbed and FTL expression is quantified. Does this perturbation result in a significant change in FTL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UXS1 is perturbed and FTL expression is quantified. Does this perturbation result in a significant change in FTL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58712
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RBMX and then measure expression of SKA3. Does this perturbation cause a significant change in SKA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RBMX and then measure expression of SKA3. Does this perturbation cause a significant change in SKA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41864
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRKRIP1 is associated with a significant change in PDIA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRKRIP1 is associated with a significant change in PDIA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38565
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSNK1A1 and then measure expression of PIGX. Does this perturbation cause a significant change in PIGX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSNK1A1 and then measure expression of PIGX. Does this perturbation cause a significant change in PIGX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9914
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF2, does the expression profile of PCOLCE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF2, does the expression profile of PCOLCE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52727
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SMARCB1 and monitor SMARCB1 expression. Decide whether this perturbation leads to a significant alteration in SMARCB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SMARCB1 and monitor SMARCB1 expression. Decide whether this perturbation leads to a significant alteration in SMARCB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48998
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBCD is perturbed and CTIF expression is measured. Determine whether CTIF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBCD is perturbed and CTIF expression is measured. Determine whether CTIF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53179
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASF1B, does the expression profile of ASF1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASF1B, does the expression profile of ASF1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2237
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB7 and then measure expression of EEF1AKMT1. Does this perturbation cause a significant change in EEF1AKMT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB7 and then measure expression of EEF1AKMT1. Does this perturbation cause a significant change in EEF1AKMT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39454
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELOB is associated with a significant change in CA9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELOB is associated with a significant change in CA9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14985
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRSF2 and monitor HACL1 expression. Decide whether this perturbation leads to a significant alteration in HACL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRSF2 and monitor HACL1 expression. Decide whether this perturbation leads to a significant alteration in HACL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51468
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMUG1 is perturbed and the expression of GPR161 is measured. Determine whether GPR161 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMUG1 is perturbed and the expression of GPR161 is measured. Determine whether GPR161 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49526
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRAPPC1 is perturbed and the expression of TRAPPC1 is measured. Does this perturbation cause a significant change in TRAPPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRAPPC1 is perturbed and the expression of TRAPPC1 is measured. Does this perturbation cause a significant change in TRAPPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55470
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EDC4 is perturbed and BID expression is quantified. Does this perturbation result in a significant change in BID expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EDC4 is perturbed and BID expression is quantified. Does this perturbation result in a significant change in BID expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13682
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SERF2 is perturbed and the expression of SERF2 is measured. Does this perturbation cause a significant change in SERF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SERF2 is perturbed and the expression of SERF2 is measured. Does this perturbation cause a significant change in SERF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47650
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SUPT6H is perturbed and LRBA expression is observed. Does this perturbation lead to a significant difference in LRBA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SUPT6H is perturbed and LRBA expression is observed. Does this perturbation lead to a significant difference in LRBA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52243
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PYURF is associated with a significant change in NFYC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PYURF is associated with a significant change in NFYC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40665
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb YKT6 and monitor YKT6 expression. Decide whether this perturbation leads to a significant alteration in YKT6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YKT6 and monitor YKT6 expression. Decide whether this perturbation leads to a significant alteration in YKT6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60818
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOSC8 is associated with a significant change in KIF15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOSC8 is associated with a significant change in KIF15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16175
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C5orf30 is perturbed and PISD expression is observed. Does this perturbation lead to a significant difference in PISD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C5orf30 is perturbed and PISD expression is observed. Does this perturbation lead to a significant difference in PISD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4603
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and AC005562.1 expression is observed. Does this perturbation lead to a significant difference in AC005562.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and AC005562.1 expression is observed. Does this perturbation lead to a significant difference in AC005562.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38223
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGLN2, does the expression profile of EGLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGLN2, does the expression profile of EGLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13927
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RRN3 is perturbed and NPHP1 expression is quantified. Does this perturbation result in a significant change in NPHP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RRN3 is perturbed and NPHP1 expression is quantified. Does this perturbation result in a significant change in NPHP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46002
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNUPN and examine the expression of SNUPN. Does perturbing SNUPN lead to a significant change in SNUPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNUPN and examine the expression of SNUPN. Does perturbing SNUPN lead to a significant change in SNUPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50281
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMC3 is perturbed and ITGA11 expression is observed. Does this perturbation lead to a significant difference in ITGA11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMC3 is perturbed and ITGA11 expression is observed. Does this perturbation lead to a significant difference in ITGA11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49143
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEH1L is perturbed and the expression of H2AFZ is measured. Determine whether H2AFZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEH1L is perturbed and the expression of H2AFZ is measured. Determine whether H2AFZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47516
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IPO7 is associated with a significant change in DNA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IPO7 is associated with a significant change in DNA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22195
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF3B and monitor EIF3B expression. Decide whether this perturbation leads to a significant alteration in EIF3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF3B and monitor EIF3B expression. Decide whether this perturbation leads to a significant alteration in EIF3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14358
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TWF1 and monitor TTF2 expression. Decide whether this perturbation leads to a significant alteration in TTF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TWF1 and monitor TTF2 expression. Decide whether this perturbation leads to a significant alteration in TTF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56698
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTMA and then measure expression of PTMA. Does this perturbation cause a significant change in PTMA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTMA and then measure expression of PTMA. Does this perturbation cause a significant change in PTMA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40354
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HAUS4 and examine the expression of ID1. Does perturbing HAUS4 lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HAUS4 and examine the expression of ID1. Does perturbing HAUS4 lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19621
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GINS1 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GINS1 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17805
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRF and then measure expression of GUK1. Does this perturbation cause a significant change in GUK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRF and then measure expression of GUK1. Does this perturbation cause a significant change in GUK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51024
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PGAM5 is perturbed and MRPL28 expression is quantified. Does this perturbation result in a significant change in MRPL28 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PGAM5 is perturbed and MRPL28 expression is quantified. Does this perturbation result in a significant change in MRPL28 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35172
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP53I13 is perturbed and PLP2 expression is measured. Determine whether PLP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP53I13 is perturbed and PLP2 expression is measured. Determine whether PLP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55219
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SKA3 is associated with a significant change in NASP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SKA3 is associated with a significant change in NASP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48445
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABCB10 is perturbed and the expression of CENPA is measured. Determine whether CENPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABCB10 is perturbed and the expression of CENPA is measured. Determine whether CENPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":216
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NBAS is associated with a significant change in SLC3A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NBAS is associated with a significant change in SLC3A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29995
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPS6, does the expression profile of KIF14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPS6, does the expression profile of KIF14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8987
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED10 and then measure expression of ABRAXAS1. Does this perturbation cause a significant change in ABRAXAS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED10 and then measure expression of ABRAXAS1. Does this perturbation cause a significant change in ABRAXAS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25434
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFAB1 and then measure expression of NDUFAB1. Does this perturbation cause a significant change in NDUFAB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFAB1 and then measure expression of NDUFAB1. Does this perturbation cause a significant change in NDUFAB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30604
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCT4 is perturbed and TRIP13 expression is measured. Determine whether TRIP13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCT4 is perturbed and TRIP13 expression is measured. Determine whether TRIP13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5769
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZCRB1 is associated with a significant change in PPHLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZCRB1 is associated with a significant change in PPHLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61215
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EEF1B2, does the expression profile of EEF1B2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EEF1B2, does the expression profile of EEF1B2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13747
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS2, does the expression profile of MCM10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS2, does the expression profile of MCM10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45277
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MCM3 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MCM3 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25134
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of PTTG1 is measured. Does this perturbation cause a significant change in PTTG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of PTTG1 is measured. Does this perturbation cause a significant change in PTTG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14110
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL32 and examine the expression of SUGCT. Does perturbing RPL32 lead to a significant change in SUGCT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL32 and examine the expression of SUGCT. Does perturbing RPL32 lead to a significant change in SUGCT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44051
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJA1, does the expression profile of DNAJA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJA1, does the expression profile of DNAJA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12487
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SF3A3 is perturbed and the expression of KIF14 is measured. Does this perturbation cause a significant change in KIF14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SF3A3 is perturbed and the expression of KIF14 is measured. Does this perturbation cause a significant change in KIF14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47950
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRPM7 and then measure expression of TRPM7. Does this perturbation cause a significant change in TRPM7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRPM7 and then measure expression of TRPM7. Does this perturbation cause a significant change in TRPM7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55874
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPD1 is perturbed and RMND5B expression is quantified. Does this perturbation result in a significant change in RMND5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPD1 is perturbed and RMND5B expression is quantified. Does this perturbation result in a significant change in RMND5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20922
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and PSAT1 expression is quantified. Does this perturbation result in a significant change in PSAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and PSAT1 expression is quantified. Does this perturbation result in a significant change in PSAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48732
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLD3 is perturbed and CDCA7 expression is measured. Determine whether CDCA7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLD3 is perturbed and CDCA7 expression is measured. Determine whether CDCA7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36309
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL18 is perturbed and MRPL18 expression is measured. Determine whether MRPL18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL18 is perturbed and MRPL18 expression is measured. Determine whether MRPL18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27159
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COX11 is perturbed and COX11 expression is measured. Determine whether COX11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COX11 is perturbed and COX11 expression is measured. Determine whether COX11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9219
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRF is perturbed and GUK1 expression is quantified. Does this perturbation result in a significant change in GUK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRF is perturbed and GUK1 expression is quantified. Does this perturbation result in a significant change in GUK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51022
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb VPS28 and monitor CXCL8 expression. Decide whether this perturbation leads to a significant alteration in CXCL8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb VPS28 and monitor CXCL8 expression. Decide whether this perturbation leads to a significant alteration in CXCL8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59058
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VPS41 is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VPS41 is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59215
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YY1 is perturbed and the expression of DMKN is measured. Does this perturbation cause a significant change in DMKN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YY1 is perturbed and the expression of DMKN is measured. Does this perturbation cause a significant change in DMKN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60940
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL37, does the expression profile of MRPL37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL37, does the expression profile of MRPL37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27637
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1143, does the expression profile of KIF15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1143, does the expression profile of KIF15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23027
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPU is perturbed and HNRNPU expression is measured. Determine whether HNRNPU exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPU is perturbed and HNRNPU expression is measured. Determine whether HNRNPU exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20589
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ASCC3 expression is measured. Determine whether ASCC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ASCC3 expression is measured. Determine whether ASCC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2199
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TUBE1 is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TUBE1 is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56482
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PMPCB is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PMPCB is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35949
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMA2 is perturbed and the expression of PIMREG is measured. Does this perturbation cause a significant change in PIMREG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMA2 is perturbed and the expression of PIMREG is measured. Does this perturbation cause a significant change in PIMREG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39140
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3I is perturbed and EIF3I expression is observed. Does this perturbation lead to a significant difference in EIF3I expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3I is perturbed and EIF3I expression is observed. Does this perturbation lead to a significant difference in EIF3I expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14493
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAMM41 is perturbed and TGFB1I1 expression is measured. Determine whether TGFB1I1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAMM41 is perturbed and TGFB1I1 expression is measured. Determine whether TGFB1I1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52909
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARL4D and then measure expression of MICAL2. Does this perturbation cause a significant change in MICAL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARL4D and then measure expression of MICAL2. Does this perturbation cause a significant change in MICAL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1974
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MED19 is perturbed and SFRP1 expression is quantified. Does this perturbation result in a significant change in SFRP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MED19 is perturbed and SFRP1 expression is quantified. Does this perturbation result in a significant change in SFRP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25532
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC62 and examine the expression of CDC25B. Does perturbing SEC62 lead to a significant change in CDC25B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC62 and examine the expression of CDC25B. Does perturbing SEC62 lead to a significant change in CDC25B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47451
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GTF2F1 and monitor NAPEPLD expression. Decide whether this perturbation leads to a significant alteration in NAPEPLD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GTF2F1 and monitor NAPEPLD expression. Decide whether this perturbation leads to a significant alteration in NAPEPLD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18908
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, METTL16 is perturbed and the expression of NRM is measured. Does this perturbation cause a significant change in NRM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, METTL16 is perturbed and the expression of NRM is measured. Does this perturbation cause a significant change in NRM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26070
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS6 is perturbed and MRPS6 expression is measured. Determine whether MRPS6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS6 is perturbed and MRPS6 expression is measured. Determine whether MRPS6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28839
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBBP4 is perturbed and the expression of OSGIN2 is measured. Determine whether OSGIN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBBP4 is perturbed and the expression of OSGIN2 is measured. Determine whether OSGIN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41376
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAPG, does the expression profile of NAPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAPG, does the expression profile of NAPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29867
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHCHD4 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHCHD4 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7314
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC11 and examine the expression of CDKN1A. Does perturbing ANAPC11 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC11 and examine the expression of CDKN1A. Does perturbing ANAPC11 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1331
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR54 and examine the expression of PGLS. Does perturbing WDR54 lead to a significant change in PGLS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR54 and examine the expression of PGLS. Does perturbing WDR54 lead to a significant change in PGLS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59921
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGPP1 is perturbed and MAP3K11 expression is quantified. Does this perturbation result in a significant change in MAP3K11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGPP1 is perturbed and MAP3K11 expression is quantified. Does this perturbation result in a significant change in MAP3K11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48202
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HMGB3 and monitor METRN expression. Decide whether this perturbation leads to a significant alteration in METRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HMGB3 and monitor METRN expression. Decide whether this perturbation leads to a significant alteration in METRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20248
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL27 is perturbed and MT-ND2 expression is measured. Determine whether MT-ND2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL27 is perturbed and MT-ND2 expression is measured. Determine whether MT-ND2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27419
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPUSD3 is perturbed and the expression of RPUSD3 is measured. Determine whether RPUSD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPUSD3 is perturbed and the expression of RPUSD3 is measured. Determine whether RPUSD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45876
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS18A is associated with a significant change in MRPS18A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS18A is associated with a significant change in MRPS18A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28305
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SP1 is perturbed and SP1 expression is observed. Does this perturbation lead to a significant difference in SP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SP1 is perturbed and SP1 expression is observed. Does this perturbation lead to a significant difference in SP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50463
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEPRO, does the expression profile of MKI67 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEPRO, does the expression profile of MKI67 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31207
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NFYB is associated with a significant change in HMGB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NFYB is associated with a significant change in HMGB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31375
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B10 is perturbed and the expression of MT-CO2 is measured. Does this perturbation cause a significant change in MT-CO2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B10 is perturbed and the expression of MT-CO2 is measured. Does this perturbation cause a significant change in MT-CO2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20690
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLRMT, does the expression profile of MT-ND5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLRMT, does the expression profile of MT-ND5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37227
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR2K and then measure expression of KIF2C. Does this perturbation cause a significant change in KIF2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR2K and then measure expression of KIF2C. Does this perturbation cause a significant change in KIF2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36874
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UXS1 and monitor FTL expression. Decide whether this perturbation leads to a significant alteration in FTL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UXS1 and monitor FTL expression. Decide whether this perturbation leads to a significant alteration in FTL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58718
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YTHDC1 is perturbed and the expression of MTHFD2L is measured. Determine whether MTHFD2L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YTHDC1 is perturbed and the expression of MTHFD2L is measured. Determine whether MTHFD2L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60926
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF8, does the expression profile of DANCR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF8, does the expression profile of DANCR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52877
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS33 is perturbed and MRPS33 expression is observed. Does this perturbation lead to a significant difference in MRPS33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS33 is perturbed and MRPS33 expression is observed. Does this perturbation lead to a significant difference in MRPS33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28733
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LDB1, does the expression profile of SAMD8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LDB1, does the expression profile of SAMD8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23767
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UMPS and examine the expression of MYEF2. Does perturbing UMPS lead to a significant change in MYEF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UMPS and examine the expression of MYEF2. Does perturbing UMPS lead to a significant change in MYEF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57701
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HMGB1 and monitor BCL2L1 expression. Decide whether this perturbation leads to a significant alteration in BCL2L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HMGB1 and monitor BCL2L1 expression. Decide whether this perturbation leads to a significant alteration in BCL2L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20208
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POLE and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POLE and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36348
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KPNA6, does the expression profile of ECHS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KPNA6, does the expression profile of ECHS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23297
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPDL1 and examine the expression of MCM4. Does perturbing SPDL1 lead to a significant change in MCM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPDL1 and examine the expression of MCM4. Does perturbing SPDL1 lead to a significant change in MCM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50741
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RAB18 is perturbed and NAGPA expression is observed. Does this perturbation lead to a significant difference in NAGPA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RAB18 is perturbed and NAGPA expression is observed. Does this perturbation lead to a significant difference in NAGPA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40753
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NAA50 is perturbed and the expression of MDM2 is measured. Does this perturbation cause a significant change in MDM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NAA50 is perturbed and the expression of MDM2 is measured. Does this perturbation cause a significant change in MDM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29690
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP88, does the expression profile of MKI67 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP88, does the expression profile of MKI67 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33367
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb THAP11 and monitor AL445524.1 expression. Decide whether this perturbation leads to a significant alteration in AL445524.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb THAP11 and monitor AL445524.1 expression. Decide whether this perturbation leads to a significant alteration in AL445524.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53818
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TKT, does the expression profile of TKT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TKT, does the expression profile of TKT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54397
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLE, does the expression profile of PARPBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLE, does the expression profile of PARPBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36337
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAM133B, does the expression profile of GINS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAM133B, does the expression profile of GINS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16307
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC86 is associated with a significant change in RRM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC86 is associated with a significant change in RRM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5395
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF3A and monitor EIF3A expression. Decide whether this perturbation leads to a significant alteration in EIF3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF3A and monitor EIF3A expression. Decide whether this perturbation leads to a significant alteration in EIF3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14318
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNM2 and then measure expression of KIAA1671. Does this perturbation cause a significant change in KIAA1671 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNM2 and then measure expression of KIAA1671. Does this perturbation cause a significant change in KIAA1671 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12764
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP20 and examine the expression of KNL1. Does perturbing UTP20 lead to a significant change in KNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP20 and examine the expression of KNL1. Does perturbing UTP20 lead to a significant change in KNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58561
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSCB is perturbed and the expression of MCM3 is measured. Does this perturbation cause a significant change in MCM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSCB is perturbed and the expression of MCM3 is measured. Does this perturbation cause a significant change in MCM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20650
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TIMP2 expression. Decide whether this perturbation leads to a significant alteration in TIMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TIMP2 expression. Decide whether this perturbation leads to a significant alteration in TIMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11058
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RRM2 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RRM2 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45979
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC16 is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC16 is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6000
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNIH4 and then measure expression of CTSK. Does this perturbation cause a significant change in CTSK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNIH4 and then measure expression of CTSK. Does this perturbation cause a significant change in CTSK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8214
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PIAS1 and then measure expression of DMKN. Does this perturbation cause a significant change in DMKN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PIAS1 and then measure expression of DMKN. Does this perturbation cause a significant change in DMKN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35534
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb THOC3 and monitor SLC43A3 expression. Decide whether this perturbation leads to a significant alteration in SLC43A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb THOC3 and monitor SLC43A3 expression. Decide whether this perturbation leads to a significant alteration in SLC43A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53928
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AURKA and then measure expression of SKA3. Does this perturbation cause a significant change in SKA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AURKA and then measure expression of SKA3. Does this perturbation cause a significant change in SKA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3164
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TOMM20, does the expression profile of MT-ND6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TOMM20, does the expression profile of MT-ND6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54947
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCT5 and monitor VRK1 expression. Decide whether this perturbation leads to a significant alteration in VRK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCT5 and monitor VRK1 expression. Decide whether this perturbation leads to a significant alteration in VRK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5818
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS26 is perturbed and the expression of MRPS26 is measured. Determine whether MRPS26 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS26 is perturbed and the expression of MRPS26 is measured. Determine whether MRPS26 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28566
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHX36 and examine the expression of NBPF10. Does perturbing DHX36 lead to a significant change in NBPF10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHX36 and examine the expression of NBPF10. Does perturbing DHX36 lead to a significant change in NBPF10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12201
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSCB is perturbed and MCM3 expression is measured. Determine whether MCM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSCB is perturbed and MCM3 expression is measured. Determine whether MCM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20659
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMG9 is perturbed and the expression of GAS5 is measured. Determine whether GAS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMG9 is perturbed and the expression of GAS5 is measured. Determine whether GAS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49436
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NUP62 and monitor PRC1 expression. Decide whether this perturbation leads to a significant alteration in PRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NUP62 and monitor PRC1 expression. Decide whether this perturbation leads to a significant alteration in PRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33328
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, USP37 is perturbed and the expression of ZNF330 is measured. Does this perturbation cause a significant change in ZNF330 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, USP37 is perturbed and the expression of ZNF330 is measured. Does this perturbation cause a significant change in ZNF330 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58280
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SUPT5H and examine the expression of TK1. Does perturbing SUPT5H lead to a significant change in TK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SUPT5H and examine the expression of TK1. Does perturbing SUPT5H lead to a significant change in TK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52211
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3M and examine the expression of SNHG7. Does perturbing EIF3M lead to a significant change in SNHG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3M and examine the expression of SNHG7. Does perturbing EIF3M lead to a significant change in SNHG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14591
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBTF is perturbed and the expression of UQCR10 is measured. Does this perturbation cause a significant change in UQCR10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBTF is perturbed and the expression of UQCR10 is measured. Does this perturbation cause a significant change in UQCR10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57560
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCLAF1, does the expression profile of BCLAF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCLAF1, does the expression profile of BCLAF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3457
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OGT is perturbed and ECHDC2 expression is quantified. Does this perturbation result in a significant change in ECHDC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OGT is perturbed and ECHDC2 expression is quantified. Does this perturbation result in a significant change in ECHDC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33592
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NRDE2 is perturbed and SYNE2 expression is observed. Does this perturbation lead to a significant difference in SYNE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NRDE2 is perturbed and SYNE2 expression is observed. Does this perturbation lead to a significant difference in SYNE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32483
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALG1 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALG1 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1139
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTR10 is perturbed and the expression of KIF18A is measured. Determine whether KIF18A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTR10 is perturbed and the expression of KIF18A is measured. Determine whether KIF18A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":596
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ALG2 and examine the expression of ABRACL. Does perturbing ALG2 lead to a significant change in ABRACL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ALG2 and examine the expression of ABRACL. Does perturbing ALG2 lead to a significant change in ABRACL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1211
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPD3 is associated with a significant change in GSDMD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPD3 is associated with a significant change in GSDMD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50155
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT8 and examine the expression of TEAD4. Does perturbing CCT8 lead to a significant change in TEAD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT8 and examine the expression of TEAD4. Does perturbing CCT8 lead to a significant change in TEAD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5901
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS15 and then measure expression of LARS2. Does this perturbation cause a significant change in LARS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS15 and then measure expression of LARS2. Does this perturbation cause a significant change in LARS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45114
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPEN is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPEN is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50769
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP133 and examine the expression of CCDC80. Does perturbing NUP133 lead to a significant change in CCDC80 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP133 and examine the expression of CCDC80. Does perturbing NUP133 lead to a significant change in CCDC80 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33051
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRPA1 is perturbed and KIF20A expression is observed. Does this perturbation lead to a significant difference in KIF20A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRPA1 is perturbed and KIF20A expression is observed. Does this perturbation lead to a significant difference in KIF20A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49983
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLD2 is perturbed and POLD2 expression is observed. Does this perturbation lead to a significant difference in POLD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLD2 is perturbed and POLD2 expression is observed. Does this perturbation lead to a significant difference in POLD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36273
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, U2SURP is perturbed and the expression of LRRCC1 is measured. Does this perturbation cause a significant change in LRRCC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, U2SURP is perturbed and the expression of LRRCC1 is measured. Does this perturbation cause a significant change in LRRCC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56960
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPC25 is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPC25 is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50640
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPE is perturbed and the expression of CAPZB is measured. Does this perturbation cause a significant change in CAPZB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPE is perturbed and the expression of CAPZB is measured. Does this perturbation cause a significant change in CAPZB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43200
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSBP and monitor ZWINT expression. Decide whether this perturbation leads to a significant alteration in ZWINT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSBP and monitor ZWINT expression. Decide whether this perturbation leads to a significant alteration in ZWINT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33818
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and HARS expression is measured. Determine whether HARS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and HARS expression is measured. Determine whether HARS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19519
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MPG is perturbed and the expression of MPG is measured. Determine whether MPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MPG is perturbed and the expression of MPG is measured. Determine whether MPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26796
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PNISR is perturbed and NDFIP2 expression is observed. Does this perturbation lead to a significant difference in NDFIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PNISR is perturbed and NDFIP2 expression is observed. Does this perturbation lead to a significant difference in NDFIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35993
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPS7 and monitor SPC24 expression. Decide whether this perturbation leads to a significant alteration in SPC24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPS7 and monitor SPC24 expression. Decide whether this perturbation leads to a significant alteration in SPC24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45768
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP11B is perturbed and IFI27L2 expression is quantified. Does this perturbation result in a significant change in IFI27L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP11B is perturbed and IFI27L2 expression is quantified. Does this perturbation result in a significant change in IFI27L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2382
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SMUG1 is perturbed and the expression of GPR161 is measured. Does this perturbation cause a significant change in GPR161 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SMUG1 is perturbed and the expression of GPR161 is measured. Does this perturbation cause a significant change in GPR161 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49520
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS18 and then measure expression of METTL4. Does this perturbation cause a significant change in METTL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS18 and then measure expression of METTL4. Does this perturbation cause a significant change in METTL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58994
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTCD3 and monitor LRRCC1 expression. Decide whether this perturbation leads to a significant alteration in LRRCC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTCD3 and monitor LRRCC1 expression. Decide whether this perturbation leads to a significant alteration in LRRCC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40268
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM9 is perturbed and SUN2 expression is quantified. Does this perturbation result in a significant change in SUN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM9 is perturbed and SUN2 expression is quantified. Does this perturbation result in a significant change in SUN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54312
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KRR1 and then measure expression of VRK1. Does this perturbation cause a significant change in VRK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KRR1 and then measure expression of VRK1. Does this perturbation cause a significant change in VRK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23394
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MED30 is perturbed and CENPN expression is quantified. Does this perturbation result in a significant change in CENPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MED30 is perturbed and CENPN expression is quantified. Does this perturbation result in a significant change in CENPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25712
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDT21 and examine the expression of ASPM. Does perturbing NUDT21 lead to a significant change in ASPM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDT21 and examine the expression of ASPM. Does perturbing NUDT21 lead to a significant change in ASPM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32901
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PGK1 is associated with a significant change in LOXL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PGK1 is associated with a significant change in LOXL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35235
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PREB is perturbed and CDCA2 expression is measured. Determine whether CDCA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PREB is perturbed and CDCA2 expression is measured. Determine whether CDCA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38349
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS2 is associated with a significant change in AARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS2 is associated with a significant change in AARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":125
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELL is perturbed and the expression of PCLAF is measured. Determine whether PCLAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELL is perturbed and the expression of PCLAF is measured. Determine whether PCLAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14946
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCT7 is perturbed and the expression of CDC45 is measured. Determine whether CDC45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCT7 is perturbed and the expression of CDC45 is measured. Determine whether CDC45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5876
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAT2A and examine the expression of MAT2A. Does perturbing MAT2A lead to a significant change in MAT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAT2A and examine the expression of MAT2A. Does perturbing MAT2A lead to a significant change in MAT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24751
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRNP48 is associated with a significant change in AC016831.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRNP48 is associated with a significant change in AC016831.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49905
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PES1, does the expression profile of HNRNPA1P48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PES1, does the expression profile of HNRNPA1P48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34847
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR2A and then measure expression of HNRNPL. Does this perturbation cause a significant change in HNRNPL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR2A and then measure expression of HNRNPL. Does this perturbation cause a significant change in HNRNPL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36604
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CMTR1 is perturbed and SLC38A1 expression is quantified. Does this perturbation result in a significant change in SLC38A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CMTR1 is perturbed and SLC38A1 expression is quantified. Does this perturbation result in a significant change in SLC38A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8142
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which THOC1 is perturbed and PKMYT1 expression is observed. Does this perturbation lead to a significant difference in PKMYT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which THOC1 is perturbed and PKMYT1 expression is observed. Does this perturbation lead to a significant difference in PKMYT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53853
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL23A is associated with a significant change in ATAD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL23A is associated with a significant change in ATAD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43715
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ANKLE2 is perturbed and the expression of PLXNA2 is measured. Determine whether PLXNA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ANKLE2 is perturbed and the expression of PLXNA2 is measured. Determine whether PLXNA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1496
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL35 is perturbed and MRPL35 expression is measured. Determine whether MRPL35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL35 is perturbed and MRPL35 expression is measured. Determine whether MRPL35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27579
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PBK expression is measured. Determine whether PBK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PBK expression is measured. Determine whether PBK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46739
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UQCRC1 is perturbed and UQCRC1 expression is measured. Determine whether UQCRC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UQCRC1 is perturbed and UQCRC1 expression is measured. Determine whether UQCRC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57909
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EMC7, does the expression profile of PLPP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EMC7, does the expression profile of PLPP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15317
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FCF1 is perturbed and the expression of SHCBP1 is measured. Determine whether SHCBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FCF1 is perturbed and the expression of SHCBP1 is measured. Determine whether SHCBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16816
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TADA2B and examine the expression of SFRP1. Does perturbing TADA2B lead to a significant change in SFRP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TADA2B and examine the expression of SFRP1. Does perturbing TADA2B lead to a significant change in SFRP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52471
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NHLRC2 is perturbed and IL7R expression is quantified. Does this perturbation result in a significant change in IL7R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NHLRC2 is perturbed and IL7R expression is quantified. Does this perturbation result in a significant change in IL7R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31422
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL15 and then measure expression of CCNB2. Does this perturbation cause a significant change in CCNB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL15 and then measure expression of CCNB2. Does this perturbation cause a significant change in CCNB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43504
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TAF2 and then measure expression of TAF2. Does this perturbation cause a significant change in TAF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TAF2 and then measure expression of TAF2. Does this perturbation cause a significant change in TAF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52714
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDK9 and monitor CLUH expression. Decide whether this perturbation leads to a significant alteration in CLUH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDK9 and monitor CLUH expression. Decide whether this perturbation leads to a significant alteration in CLUH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6598
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SDC1 and examine the expression of NDUFB1. Does perturbing SDC1 lead to a significant change in NDUFB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SDC1 and examine the expression of NDUFB1. Does perturbing SDC1 lead to a significant change in NDUFB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47101
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOSC1 is perturbed and DTL expression is quantified. Does this perturbation result in a significant change in DTL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOSC1 is perturbed and DTL expression is quantified. Does this perturbation result in a significant change in DTL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15962
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNUPN is perturbed and the expression of TSEN15 is measured. Determine whether TSEN15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNUPN is perturbed and the expression of TSEN15 is measured. Determine whether TSEN15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50306
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CIAPIN1 is perturbed and RPL22L1 expression is measured. Determine whether RPL22L1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CIAPIN1 is perturbed and RPL22L1 expression is measured. Determine whether RPL22L1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7769
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPTSSA and then measure expression of SPTSSA. Does this perturbation cause a significant change in SPTSSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPTSSA and then measure expression of SPTSSA. Does this perturbation cause a significant change in SPTSSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50884
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL28 is perturbed and the expression of TMPO-AS1 is measured. Determine whether TMPO-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL28 is perturbed and the expression of TMPO-AS1 is measured. Determine whether TMPO-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43916
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC16 is perturbed and the expression of CDC16 is measured. Does this perturbation cause a significant change in CDC16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC16 is perturbed and the expression of CDC16 is measured. Does this perturbation cause a significant change in CDC16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6010
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NFRKB is perturbed and INO80 expression is quantified. Does this perturbation result in a significant change in INO80 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NFRKB is perturbed and INO80 expression is quantified. Does this perturbation result in a significant change in INO80 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31312
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL26L1 is perturbed and the expression of RPL26L1 is measured. Does this perturbation cause a significant change in RPL26L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL26L1 is perturbed and the expression of RPL26L1 is measured. Does this perturbation cause a significant change in RPL26L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43800
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UPF1 and examine the expression of EPB41L4A-AS1. Does perturbing UPF1 lead to a significant change in EPB41L4A-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UPF1 and examine the expression of EPB41L4A-AS1. Does perturbing UPF1 lead to a significant change in EPB41L4A-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57801
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRPD2 and then measure expression of NARS2. Does this perturbation cause a significant change in NARS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRPD2 and then measure expression of NARS2. Does this perturbation cause a significant change in NARS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50114
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL30 and then measure expression of NDC80. Does this perturbation cause a significant change in NDC80 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL30 and then measure expression of NDC80. Does this perturbation cause a significant change in NDC80 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44004
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COG2 and then measure expression of COG2. Does this perturbation cause a significant change in COG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COG2 and then measure expression of COG2. Does this perturbation cause a significant change in COG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8524
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNTB2 and then measure expression of AL161431.1. Does this perturbation cause a significant change in AL161431.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNTB2 and then measure expression of AL161431.1. Does this perturbation cause a significant change in AL161431.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50274
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPLP0 is perturbed and PCLAF expression is quantified. Does this perturbation result in a significant change in PCLAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPLP0 is perturbed and PCLAF expression is quantified. Does this perturbation result in a significant change in PCLAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44612
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD17A and examine the expression of DNAJC4. Does perturbing ABHD17A lead to a significant change in DNAJC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD17A and examine the expression of DNAJC4. Does perturbing ABHD17A lead to a significant change in DNAJC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":381
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ISCU and monitor CPT2 expression. Decide whether this perturbation leads to a significant alteration in CPT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ISCU and monitor CPT2 expression. Decide whether this perturbation leads to a significant alteration in CPT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22308
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NAA25 is perturbed and ZMAT3 expression is measured. Determine whether ZMAT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NAA25 is perturbed and ZMAT3 expression is measured. Determine whether ZMAT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29579
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CMPK1 and then measure expression of CMPK1. Does this perturbation cause a significant change in CMPK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CMPK1 and then measure expression of CMPK1. Does this perturbation cause a significant change in CMPK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8104
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD1 is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD1 is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30993
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID5B is perturbed and the expression of AFF4 is measured. Does this perturbation cause a significant change in AFF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID5B is perturbed and the expression of AFF4 is measured. Does this perturbation cause a significant change in AFF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1880
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOL12 is perturbed and the expression of POLA2 is measured. Does this perturbation cause a significant change in POLA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOL12 is perturbed and the expression of POLA2 is measured. Does this perturbation cause a significant change in POLA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31900
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DROSHA and monitor CD109 expression. Decide whether this perturbation leads to a significant alteration in CD109 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DROSHA and monitor CD109 expression. Decide whether this perturbation leads to a significant alteration in CD109 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13208
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS33 is perturbed and ARL2 expression is observed. Does this perturbation lead to a significant difference in ARL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS33 is perturbed and ARL2 expression is observed. Does this perturbation lead to a significant difference in ARL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28723
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSGEP and examine the expression of SNHG32. Does perturbing OSGEP lead to a significant change in SNHG32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSGEP and examine the expression of SNHG32. Does perturbing OSGEP lead to a significant change in SNHG32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33861
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM199 is perturbed and TMEM199 expression is quantified. Does this perturbation result in a significant change in TMEM199 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM199 is perturbed and TMEM199 expression is quantified. Does this perturbation result in a significant change in TMEM199 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54662
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and CDCA5 expression is measured. Determine whether CDCA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and CDCA5 expression is measured. Determine whether CDCA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46579
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPP30 is perturbed and the expression of SKA3 is measured. Determine whether SKA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPP30 is perturbed and the expression of SKA3 is measured. Determine whether SKA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44826
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DR1 is perturbed and DR1 expression is measured. Determine whether DR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DR1 is perturbed and DR1 expression is measured. Determine whether DR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13139
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZW10 is perturbed and ZW10 expression is measured. Determine whether ZW10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZW10 is perturbed and ZW10 expression is measured. Determine whether ZW10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62019
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD1 is perturbed and CDCA5 expression is quantified. Does this perturbation result in a significant change in CDCA5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD1 is perturbed and CDCA5 expression is quantified. Does this perturbation result in a significant change in CDCA5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39682
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDC1 is perturbed and COPS6 expression is observed. Does this perturbation lead to a significant difference in COPS6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDC1 is perturbed and COPS6 expression is observed. Does this perturbation lead to a significant difference in COPS6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30373
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4A3 is perturbed and TARBP1 expression is measured. Determine whether TARBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4A3 is perturbed and TARBP1 expression is measured. Determine whether TARBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14669
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAK16 is perturbed and the expression of NUSAP1 is measured. Does this perturbation cause a significant change in NUSAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAK16 is perturbed and the expression of NUSAP1 is measured. Does this perturbation cause a significant change in NUSAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24620
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AP2A1 is perturbed and RRM2 expression is quantified. Does this perturbation result in a significant change in RRM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AP2A1 is perturbed and RRM2 expression is quantified. Does this perturbation result in a significant change in RRM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1642
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB6 is perturbed and the expression of ATF3 is measured. Does this perturbation cause a significant change in ATF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB6 is perturbed and the expression of ATF3 is measured. Does this perturbation cause a significant change in ATF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30830
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTEN is perturbed and AMIGO2 expression is measured. Determine whether AMIGO2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTEN is perturbed and AMIGO2 expression is measured. Determine whether AMIGO2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40309
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FAM136A and monitor SNRPG expression. Decide whether this perturbation leads to a significant alteration in SNRPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FAM136A and monitor SNRPG expression. Decide whether this perturbation leads to a significant alteration in SNRPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16338
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POLD1 and monitor POLD1 expression. Decide whether this perturbation leads to a significant alteration in POLD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POLD1 and monitor POLD1 expression. Decide whether this perturbation leads to a significant alteration in POLD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36258
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP155 is perturbed and the expression of ZBTB24 is measured. Determine whether ZBTB24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP155 is perturbed and the expression of ZBTB24 is measured. Determine whether ZBTB24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33116
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PABPC4 and monitor NENF expression. Decide whether this perturbation leads to a significant alteration in NENF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PABPC4 and monitor NENF expression. Decide whether this perturbation leads to a significant alteration in NENF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33978
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3C3 is perturbed and TNNT1 expression is quantified. Does this perturbation result in a significant change in TNNT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3C3 is perturbed and TNNT1 expression is quantified. Does this perturbation result in a significant change in TNNT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19182
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP6V1A is perturbed and HMGCS1 expression is quantified. Does this perturbation result in a significant change in HMGCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP6V1A is perturbed and HMGCS1 expression is quantified. Does this perturbation result in a significant change in HMGCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2862
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPJ is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPJ is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6845
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DCTN3 is perturbed and CKS1B expression is observed. Does this perturbation lead to a significant difference in CKS1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DCTN3 is perturbed and CKS1B expression is observed. Does this perturbation lead to a significant difference in CKS1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10883
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of METTL1, does the expression profile of ATP5F1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of METTL1, does the expression profile of ATP5F1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26017
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNF40, does the expression profile of RPL22L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNF40, does the expression profile of RPL22L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42787
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BUD13, does the expression profile of FANCI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BUD13, does the expression profile of FANCI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4287
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VBP1 and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VBP1 and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58824
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb VPS51 and monitor ARHGEF9 expression. Decide whether this perturbation leads to a significant alteration in ARHGEF9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb VPS51 and monitor ARHGEF9 expression. Decide whether this perturbation leads to a significant alteration in ARHGEF9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59238
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNRNPU is perturbed and the expression of NT5E is measured. Does this perturbation cause a significant change in NT5E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNRNPU is perturbed and the expression of NT5E is measured. Does this perturbation cause a significant change in NT5E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20600
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL55 is perturbed and the expression of MRPL55 is measured. Determine whether MRPL55 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL55 is perturbed and the expression of MRPL55 is measured. Determine whether MRPL55 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28056
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDB1 is perturbed and the expression of GCNT2 is measured. Does this perturbation cause a significant change in GCNT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDB1 is perturbed and the expression of GCNT2 is measured. Does this perturbation cause a significant change in GCNT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11030
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRSF6 is perturbed and FAM200B expression is observed. Does this perturbation lead to a significant difference in FAM200B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRSF6 is perturbed and FAM200B expression is observed. Does this perturbation lead to a significant difference in FAM200B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51533
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFA4 is associated with a significant change in NDUFA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFA4 is associated with a significant change in NDUFA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30515
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAF7 is associated with a significant change in NDUFV2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAF7 is associated with a significant change in NDUFV2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52845
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3B and then measure expression of PCLAF. Does this perturbation cause a significant change in PCLAF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3B and then measure expression of PCLAF. Does this perturbation cause a significant change in PCLAF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14364
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of H2AFX is associated with a significant change in TRABD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of H2AFX is associated with a significant change in TRABD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19435
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF10 is perturbed and TAF10 expression is measured. Determine whether TAF10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF10 is perturbed and TAF10 expression is measured. Determine whether TAF10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52549
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AP2M1 is perturbed and INSIG1 expression is measured. Determine whether INSIG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AP2M1 is perturbed and INSIG1 expression is measured. Determine whether INSIG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1669
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTC4 is perturbed and SELENOF expression is observed. Does this perturbation lead to a significant difference in SELENOF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTC4 is perturbed and SELENOF expression is observed. Does this perturbation lead to a significant difference in SELENOF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56203
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GPN2 and then measure expression of SIM2. Does this perturbation cause a significant change in SIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GPN2 and then measure expression of SIM2. Does this perturbation cause a significant change in SIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18464
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AC118549.1, does the expression profile of RPL26 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AC118549.1, does the expression profile of RPL26 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":447
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCNQ and monitor CCNE2 expression. Decide whether this perturbation leads to a significant alteration in CCNE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCNQ and monitor CCNE2 expression. Decide whether this perturbation leads to a significant alteration in CCNE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5668
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD14 is perturbed and the expression of GABARAPL1 is measured. Does this perturbation cause a significant change in GABARAPL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD14 is perturbed and the expression of GABARAPL1 is measured. Does this perturbation cause a significant change in GABARAPL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39780
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SDAD1 is perturbed and WDR76 expression is quantified. Does this perturbation result in a significant change in WDR76 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SDAD1 is perturbed and WDR76 expression is quantified. Does this perturbation result in a significant change in WDR76 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47082
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTB, does the expression profile of TAGLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTB, does the expression profile of TAGLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":527
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF720 is perturbed and DBF4B expression is observed. Does this perturbation lead to a significant difference in DBF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF720 is perturbed and DBF4B expression is observed. Does this perturbation lead to a significant difference in DBF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61713
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SIN3A is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SIN3A is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48359
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELP6, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELP6, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15207
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EXOC8 is perturbed and the expression of KRT81 is measured. Does this perturbation cause a significant change in KRT81 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EXOC8 is perturbed and the expression of KRT81 is measured. Does this perturbation cause a significant change in KRT81 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15950
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CFL1 and monitor NIPA2 expression. Decide whether this perturbation leads to a significant alteration in NIPA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CFL1 and monitor NIPA2 expression. Decide whether this perturbation leads to a significant alteration in NIPA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7138
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOL11 and then measure expression of CDC20. Does this perturbation cause a significant change in CDC20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOL11 and then measure expression of CDC20. Does this perturbation cause a significant change in CDC20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31874
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX16 is associated with a significant change in PRKDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX16 is associated with a significant change in PRKDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12075
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and OIP5 expression is measured. Determine whether OIP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and OIP5 expression is measured. Determine whether OIP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8759
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR44 is perturbed and SLC38A1 expression is measured. Determine whether SLC38A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR44 is perturbed and SLC38A1 expression is measured. Determine whether SLC38A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59849
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of RABEP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of RABEP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16527
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPL26L1 and monitor RPL26L1 expression. Decide whether this perturbation leads to a significant alteration in RPL26L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPL26L1 and monitor RPL26L1 expression. Decide whether this perturbation leads to a significant alteration in RPL26L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43808
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC7 and then measure expression of MASTL. Does this perturbation cause a significant change in MASTL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC7 and then measure expression of MASTL. Does this perturbation cause a significant change in MASTL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16154
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KEAP1, does the expression profile of GNAI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KEAP1, does the expression profile of GNAI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22967
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UTP11 is perturbed and DLGAP5 expression is measured. Determine whether DLGAP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UTP11 is perturbed and DLGAP5 expression is measured. Determine whether DLGAP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58499
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SDR39U1 is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SDR39U1 is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47296
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2H is perturbed and UBE2H expression is measured. Determine whether UBE2H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2H is perturbed and UBE2H expression is measured. Determine whether UBE2H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57219
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSEN34 and examine the expression of TSEN34. Does perturbing TSEN34 lead to a significant change in TSEN34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSEN34 and examine the expression of TSEN34. Does perturbing TSEN34 lead to a significant change in TSEN34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55951
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTOR and then measure expression of BIRC5. Does this perturbation cause a significant change in BIRC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTOR and then measure expression of BIRC5. Does this perturbation cause a significant change in BIRC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29154
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VARS and then measure expression of NUPR1. Does this perturbation cause a significant change in NUPR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VARS and then measure expression of NUPR1. Does this perturbation cause a significant change in NUPR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58784
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, H2AFX is perturbed and KDM6A expression is quantified. Does this perturbation result in a significant change in KDM6A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, H2AFX is perturbed and KDM6A expression is quantified. Does this perturbation result in a significant change in KDM6A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19422
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPAP2 and examine the expression of DIMT1. Does perturbing RPAP2 lead to a significant change in DIMT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPAP2 and examine the expression of DIMT1. Does perturbing RPAP2 lead to a significant change in DIMT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43151
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which WNK1 is perturbed and WNK1 expression is observed. Does this perturbation lead to a significant difference in WNK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which WNK1 is perturbed and WNK1 expression is observed. Does this perturbation lead to a significant difference in WNK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60283
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM3, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM3, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25127
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TAF7 and monitor HEATR5A expression. Decide whether this perturbation leads to a significant alteration in HEATR5A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TAF7 and monitor HEATR5A expression. Decide whether this perturbation leads to a significant alteration in HEATR5A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52838
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BANF1 is perturbed and SV2A expression is observed. Does this perturbation lead to a significant difference in SV2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BANF1 is perturbed and SV2A expression is observed. Does this perturbation lead to a significant difference in SV2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3263
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS8 is perturbed and the expression of PRC1 is measured. Determine whether PRC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS8 is perturbed and the expression of PRC1 is measured. Determine whether PRC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22106
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPL27 and monitor MKI67 expression. Decide whether this perturbation leads to a significant alteration in MKI67 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPL27 and monitor MKI67 expression. Decide whether this perturbation leads to a significant alteration in MKI67 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43858
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP133 is perturbed and TUBB4B expression is observed. Does this perturbation lead to a significant difference in TUBB4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP133 is perturbed and TUBB4B expression is observed. Does this perturbation lead to a significant difference in TUBB4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33033
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FIP1L1 and monitor BMPR2 expression. Decide whether this perturbation leads to a significant alteration in BMPR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FIP1L1 and monitor BMPR2 expression. Decide whether this perturbation leads to a significant alteration in BMPR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16958
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TNPO3 is perturbed and CCDC18 expression is quantified. Does this perturbation result in a significant change in CCDC18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TNPO3 is perturbed and CCDC18 expression is quantified. Does this perturbation result in a significant change in CCDC18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54842
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEP192 and examine the expression of NASP. Does perturbing CEP192 lead to a significant change in NASP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEP192 and examine the expression of NASP. Does perturbing CEP192 lead to a significant change in NASP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7041
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HMGCS1 and monitor HMGCS1 expression. Decide whether this perturbation leads to a significant alteration in HMGCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HMGCS1 and monitor HMGCS1 expression. Decide whether this perturbation leads to a significant alteration in HMGCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20288
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED27 is perturbed and the expression of ATAD2 is measured. Determine whether ATAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED27 is perturbed and the expression of ATAD2 is measured. Determine whether ATAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25666
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NASP, does the expression profile of NASP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NASP, does the expression profile of NASP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29947
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LAS1L is perturbed and BARD1 expression is quantified. Does this perturbation result in a significant change in BARD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LAS1L is perturbed and BARD1 expression is quantified. Does this perturbation result in a significant change in BARD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23752
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CMTR1 is associated with a significant change in NEDD8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CMTR1 is associated with a significant change in NEDD8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8155
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IMPA2 and monitor EMG1 expression. Decide whether this perturbation leads to a significant alteration in EMG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IMPA2 and monitor EMG1 expression. Decide whether this perturbation leads to a significant alteration in EMG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21448
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CWC15 is perturbed and FBXO32 expression is observed. Does this perturbation lead to a significant difference in FBXO32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CWC15 is perturbed and FBXO32 expression is observed. Does this perturbation lead to a significant difference in FBXO32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10343
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NFYB is perturbed and HMGB3 expression is quantified. Does this perturbation result in a significant change in HMGB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NFYB is perturbed and HMGB3 expression is quantified. Does this perturbation result in a significant change in HMGB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31372
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AP2S1 is perturbed and AP2S1 expression is quantified. Does this perturbation result in a significant change in AP2S1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AP2S1 is perturbed and AP2S1 expression is quantified. Does this perturbation result in a significant change in AP2S1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1682
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCBP2 is perturbed and SNHG4 expression is observed. Does this perturbation lead to a significant difference in SNHG4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCBP2 is perturbed and SNHG4 expression is observed. Does this perturbation lead to a significant difference in SNHG4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30253
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, VCP is perturbed and the expression of KIAA1841 is measured. Determine whether KIAA1841 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, VCP is perturbed and the expression of KIAA1841 is measured. Determine whether KIAA1841 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58846
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM4 and then measure expression of MT-ND2. Does this perturbation cause a significant change in MT-ND2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM4 and then measure expression of MT-ND2. Does this perturbation cause a significant change in MT-ND2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38294
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM22 is perturbed and the expression of TIMM22 is measured. Determine whether TIMM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM22 is perturbed and the expression of TIMM22 is measured. Determine whether TIMM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54186
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GABPB1 is associated with a significant change in GABPB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GABPB1 is associated with a significant change in GABPB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17225
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD4B, does the expression profile of TPGS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD4B, does the expression profile of TPGS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46557
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP6C is perturbed and ANGPTL4 expression is measured. Determine whether ANGPTL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP6C is perturbed and ANGPTL4 expression is measured. Determine whether ANGPTL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38189
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1G1 and examine the expression of SCD. Does perturbing ATP6V1G1 lead to a significant change in SCD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1G1 and examine the expression of SCD. Does perturbing ATP6V1G1 lead to a significant change in SCD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3051
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PABPC4 is perturbed and CNN2 expression is quantified. Does this perturbation result in a significant change in CNN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PABPC4 is perturbed and CNN2 expression is quantified. Does this perturbation result in a significant change in CNN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33982
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EEF1G is perturbed and the expression of PSAT1 is measured. Determine whether PSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EEF1G is perturbed and the expression of PSAT1 is measured. Determine whether PSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13796
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MED21 is perturbed and SPC25 expression is measured. Determine whether SPC25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MED21 is perturbed and SPC25 expression is measured. Determine whether SPC25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25589
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRSF1 is perturbed and PSMB9 expression is observed. Does this perturbation lead to a significant difference in PSMB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRSF1 is perturbed and PSMB9 expression is observed. Does this perturbation lead to a significant difference in PSMB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51373
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPG is perturbed and LRRCC1 expression is measured. Determine whether LRRCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPG is perturbed and LRRCC1 expression is measured. Determine whether LRRCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50249
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAGLU, does the expression profile of ARMCX6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NAGLU, does the expression profile of ARMCX6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29817
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOL11 is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOL11 is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31876
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL44, does the expression profile of MRPL44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL44, does the expression profile of MRPL44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27847
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP6V1B2 and monitor MSMO1 expression. Decide whether this perturbation leads to a significant alteration in MSMO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP6V1B2 and monitor MSMO1 expression. Decide whether this perturbation leads to a significant alteration in MSMO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2898
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2N is perturbed and RND3 expression is quantified. Does this perturbation result in a significant change in RND3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2N is perturbed and RND3 expression is quantified. Does this perturbation result in a significant change in RND3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57352
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF1 and then measure expression of EIF1. Does this perturbation cause a significant change in EIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF1 and then measure expression of EIF1. Does this perturbation cause a significant change in EIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13984
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARIH1 and monitor SNHG4 expression. Decide whether this perturbation leads to a significant alteration in SNHG4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARIH1 and monitor SNHG4 expression. Decide whether this perturbation leads to a significant alteration in SNHG4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1908
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MPHOSPH10 and examine the expression of KIF4A. Does perturbing MPHOSPH10 lead to a significant change in KIF4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MPHOSPH10 and examine the expression of KIF4A. Does perturbing MPHOSPH10 lead to a significant change in KIF4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26841
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK12 and then measure expression of DIO2. Does this perturbation cause a significant change in DIO2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK12 and then measure expression of DIO2. Does this perturbation cause a significant change in DIO2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6494
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP53RK and examine the expression of GAS5. Does perturbing TP53RK lead to a significant change in GAS5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP53RK and examine the expression of GAS5. Does perturbing TP53RK lead to a significant change in GAS5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55241
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NAGLU is associated with a significant change in ARMCX6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NAGLU is associated with a significant change in ARMCX6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29815
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MBTPS2 is associated with a significant change in FAM114A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MBTPS2 is associated with a significant change in FAM114A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24985
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP3 is perturbed and the expression of CHMP3 is measured. Does this perturbation cause a significant change in CHMP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP3 is perturbed and the expression of CHMP3 is measured. Does this perturbation cause a significant change in CHMP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7490
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B10 and monitor HSD17B10 expression. Decide whether this perturbation leads to a significant alteration in HSD17B10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B10 and monitor HSD17B10 expression. Decide whether this perturbation leads to a significant alteration in HSD17B10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20678
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FAM133B and then measure expression of CC2D1B. Does this perturbation cause a significant change in CC2D1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FAM133B and then measure expression of CC2D1B. Does this perturbation cause a significant change in CC2D1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16314
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBE3C is perturbed and MIEN1 expression is observed. Does this perturbation lead to a significant difference in MIEN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBE3C is perturbed and MIEN1 expression is observed. Does this perturbation lead to a significant difference in MIEN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57393
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPA2 is perturbed and CMC4 expression is measured. Determine whether CMC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPA2 is perturbed and CMC4 expression is measured. Determine whether CMC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37439
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBE2M is associated with a significant change in TXNRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBE2M is associated with a significant change in TXNRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57315
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RSL1D1 and examine the expression of RSL1D1. Does perturbing RSL1D1 lead to a significant change in RSL1D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RSL1D1 and examine the expression of RSL1D1. Does perturbing RSL1D1 lead to a significant change in RSL1D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46201
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS2 and then measure expression of MT-ND2. Does this perturbation cause a significant change in MT-ND2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS2 and then measure expression of MT-ND2. Does this perturbation cause a significant change in MT-ND2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28394
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC1 and examine the expression of TRAPPC1. Does perturbing TRAPPC1 lead to a significant change in TRAPPC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC1 and examine the expression of TRAPPC1. Does perturbing TRAPPC1 lead to a significant change in TRAPPC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55471
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PDAP1 and monitor NUPR1 expression. Decide whether this perturbation leads to a significant alteration in NUPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDAP1 and monitor NUPR1 expression. Decide whether this perturbation leads to a significant alteration in NUPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34458
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of THOC3 is associated with a significant change in THOC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of THOC3 is associated with a significant change in THOC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53935
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMC3, does the expression profile of PPP1R13L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMC3, does the expression profile of PPP1R13L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49157
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ACTR2 and then measure expression of AGTPBP1. Does this perturbation cause a significant change in AGTPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ACTR2 and then measure expression of AGTPBP1. Does this perturbation cause a significant change in AGTPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":674
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRIM1 is perturbed and SKA3 expression is measured. Determine whether SKA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRIM1 is perturbed and SKA3 expression is measured. Determine whether SKA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38459
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2L, does the expression profile of CEP192 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2L, does the expression profile of CEP192 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36907
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPC25, does the expression profile of MCM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPC25, does the expression profile of MCM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50657
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GUK1 is perturbed and RPL39L expression is measured. Determine whether RPL39L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GUK1 is perturbed and RPL39L expression is measured. Determine whether RPL39L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19369
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL37A is perturbed and the expression of KIF15 is measured. Determine whether KIF15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL37A is perturbed and the expression of KIF15 is measured. Determine whether KIF15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44296
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SF3A2, does the expression profile of ZMAT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SF3A2, does the expression profile of ZMAT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47937
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC59 is associated with a significant change in FANCD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC59 is associated with a significant change in FANCD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5305
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RACK1 is perturbed and the expression of LMNB1 is measured. Does this perturbation cause a significant change in LMNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RACK1 is perturbed and the expression of LMNB1 is measured. Does this perturbation cause a significant change in LMNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41000
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of PLK4. Does this perturbation cause a significant change in PLK4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of PLK4. Does this perturbation cause a significant change in PLK4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35834
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which VPS18 is perturbed and METTL4 expression is observed. Does this perturbation lead to a significant difference in METTL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which VPS18 is perturbed and METTL4 expression is observed. Does this perturbation lead to a significant difference in METTL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58993
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFB1M is perturbed and the expression of MT-CYB is measured. Determine whether MT-CYB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFB1M is perturbed and the expression of MT-CYB is measured. Determine whether MT-CYB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53606
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCR, does the expression profile of TRAPPC2L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCR, does the expression profile of TRAPPC2L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3487
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PUF60 and monitor SAT1 expression. Decide whether this perturbation leads to a significant alteration in SAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PUF60 and monitor SAT1 expression. Decide whether this perturbation leads to a significant alteration in SAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40508
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SDHD is perturbed and DPYSL4 expression is quantified. Does this perturbation result in a significant change in DPYSL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SDHD is perturbed and DPYSL4 expression is quantified. Does this perturbation result in a significant change in DPYSL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47272
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UNC45A is perturbed and the expression of HDDC3 is measured. Does this perturbation cause a significant change in HDDC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UNC45A is perturbed and the expression of HDDC3 is measured. Does this perturbation cause a significant change in HDDC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57720
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CYFIP1, does the expression profile of CYFIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CYFIP1, does the expression profile of CYFIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10537
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MTG2 and monitor MT-ND2 expression. Decide whether this perturbation leads to a significant alteration in MT-ND2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MTG2 and monitor MT-ND2 expression. Decide whether this perturbation leads to a significant alteration in MT-ND2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29088
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC17 is perturbed and PRKDC expression is quantified. Does this perturbation result in a significant change in PRKDC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC17 is perturbed and PRKDC expression is quantified. Does this perturbation result in a significant change in PRKDC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12572
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SERF2 and monitor WDR76 expression. Decide whether this perturbation leads to a significant alteration in WDR76 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SERF2 and monitor WDR76 expression. Decide whether this perturbation leads to a significant alteration in WDR76 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47668
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCTN3 is perturbed and the expression of NUSAP1 is measured. Determine whether NUSAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCTN3 is perturbed and the expression of NUSAP1 is measured. Determine whether NUSAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10876
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MSTO1 is perturbed and the expression of ARHGAP26 is measured. Does this perturbation cause a significant change in ARHGAP26 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MSTO1 is perturbed and the expression of ARHGAP26 is measured. Does this perturbation cause a significant change in ARHGAP26 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29030
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which THAP11 is perturbed and AL445524.1 expression is observed. Does this perturbation lead to a significant difference in AL445524.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which THAP11 is perturbed and AL445524.1 expression is observed. Does this perturbation lead to a significant difference in AL445524.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53813
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, THRAP3 is perturbed and THRAP3 expression is quantified. Does this perturbation result in a significant change in THRAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, THRAP3 is perturbed and THRAP3 expression is quantified. Does this perturbation result in a significant change in THRAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54032
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARCN1 and monitor PCLAF expression. Decide whether this perturbation leads to a significant alteration in PCLAF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARCN1 and monitor PCLAF expression. Decide whether this perturbation leads to a significant alteration in PCLAF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1758
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C1orf131 is perturbed and the expression of KNL1 is measured. Determine whether KNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C1orf131 is perturbed and the expression of KNL1 is measured. Determine whether KNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4566
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PMPCA is perturbed and MT-CO3 expression is observed. Does this perturbation lead to a significant difference in MT-CO3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PMPCA is perturbed and MT-CO3 expression is observed. Does this perturbation lead to a significant difference in MT-CO3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35933
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KDM2A is perturbed and the expression of SSR2 is measured. Does this perturbation cause a significant change in SSR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KDM2A is perturbed and the expression of SSR2 is measured. Does this perturbation cause a significant change in SSR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22860
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which WDR74 is perturbed and TMEM120A expression is observed. Does this perturbation lead to a significant difference in TMEM120A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which WDR74 is perturbed and TMEM120A expression is observed. Does this perturbation lead to a significant difference in TMEM120A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60053
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NVL is perturbed and the expression of KIF4A is measured. Determine whether KIF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NVL is perturbed and the expression of KIF4A is measured. Determine whether KIF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33496
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MYCBP is perturbed and SLF1 expression is measured. Determine whether SLF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MYCBP is perturbed and SLF1 expression is measured. Determine whether SLF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29349
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBE2H and then measure expression of PLAU. Does this perturbation cause a significant change in PLAU expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBE2H and then measure expression of PLAU. Does this perturbation cause a significant change in PLAU expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57234
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CINP, does the expression profile of FANCA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CINP, does the expression profile of FANCA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7787
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMB1 is perturbed and NRGN expression is measured. Determine whether NRGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMB1 is perturbed and NRGN expression is measured. Determine whether NRGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39299
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PEF1 is perturbed and the expression of RBM24 is measured. Determine whether RBM24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PEF1 is perturbed and the expression of RBM24 is measured. Determine whether RBM24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34756
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UMPS is perturbed and CCL2 expression is quantified. Does this perturbation result in a significant change in CCL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UMPS is perturbed and CCL2 expression is quantified. Does this perturbation result in a significant change in CCL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57712
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3B3 and examine the expression of DNMT1. Does perturbing SF3B3 lead to a significant change in DNMT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3B3 and examine the expression of DNMT1. Does perturbing SF3B3 lead to a significant change in DNMT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48051
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF3C6 is perturbed and the expression of NDUFB8 is measured. Determine whether NDUFB8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF3C6 is perturbed and the expression of NDUFB8 is measured. Determine whether NDUFB8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19276
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SF1 is perturbed and SF1 expression is quantified. Does this perturbation result in a significant change in SF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SF1 is perturbed and SF1 expression is quantified. Does this perturbation result in a significant change in SF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47862
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and SEC61A1 expression is observed. Does this perturbation lead to a significant difference in SEC61A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and SEC61A1 expression is observed. Does this perturbation lead to a significant difference in SEC61A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47343
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TUBB2A is perturbed and RRAS expression is quantified. Does this perturbation result in a significant change in RRAS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TUBB2A is perturbed and RRAS expression is quantified. Does this perturbation result in a significant change in RRAS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56452
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLNS1A is perturbed and LRRC45 expression is observed. Does this perturbation lead to a significant difference in LRRC45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLNS1A is perturbed and LRRC45 expression is observed. Does this perturbation lead to a significant difference in LRRC45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7903
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSP90B1 is perturbed and HSPA5 expression is measured. Determine whether HSPA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSP90B1 is perturbed and HSPA5 expression is measured. Determine whether HSPA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20779
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ECD, does the expression profile of CENPM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ECD, does the expression profile of CENPM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13647
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATL2 and monitor IFRD1 expression. Decide whether this perturbation leads to a significant alteration in IFRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATL2 and monitor IFRD1 expression. Decide whether this perturbation leads to a significant alteration in IFRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2358
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS25 is perturbed and MRPS25 expression is measured. Determine whether MRPS25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS25 is perturbed and MRPS25 expression is measured. Determine whether MRPS25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28539
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA8 and examine the expression of TMED3. Does perturbing HSPA8 lead to a significant change in TMED3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA8 and examine the expression of TMED3. Does perturbing HSPA8 lead to a significant change in TMED3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20871
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRNT1 and examine the expression of TRIB3. Does perturbing TRNT1 lead to a significant change in TRIB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRNT1 and examine the expression of TRIB3. Does perturbing TRNT1 lead to a significant change in TRIB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55841
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHAF1B is perturbed and PLCXD1 expression is quantified. Does this perturbation result in a significant change in PLCXD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHAF1B is perturbed and PLCXD1 expression is quantified. Does this perturbation result in a significant change in PLCXD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7192
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF3H is perturbed and the expression of CNOT3 is measured. Determine whether CNOT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF3H is perturbed and the expression of CNOT3 is measured. Determine whether CNOT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14486
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBM39 is perturbed and the expression of STAMBPL1 is measured. Does this perturbation cause a significant change in STAMBPL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBM39 is perturbed and the expression of STAMBPL1 is measured. Does this perturbation cause a significant change in STAMBPL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41700
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CWC25 and then measure expression of LRWD1. Does this perturbation cause a significant change in LRWD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CWC25 and then measure expression of LRWD1. Does this perturbation cause a significant change in LRWD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10404
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HEATR1 is perturbed and NDC80 expression is quantified. Does this perturbation result in a significant change in NDC80 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HEATR1 is perturbed and NDC80 expression is quantified. Does this perturbation result in a significant change in NDC80 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19842
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PKM and examine the expression of MARVELD1. Does perturbing PKM lead to a significant change in MARVELD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PKM and examine the expression of MARVELD1. Does perturbing PKM lead to a significant change in MARVELD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35711
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZDHHC7 is perturbed and the expression of AXL is measured. Determine whether AXL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZDHHC7 is perturbed and the expression of AXL is measured. Determine whether AXL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61246
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SMC6 is perturbed and LMNB1 expression is measured. Determine whether LMNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SMC6 is perturbed and LMNB1 expression is measured. Determine whether LMNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49259
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELP6 is associated with a significant change in PSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELP6 is associated with a significant change in PSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15195
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AKIRIN2, does the expression profile of SOX11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AKIRIN2, does the expression profile of SOX11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1077
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCDC174 is perturbed and FANCL expression is measured. Determine whether FANCL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCDC174 is perturbed and FANCL expression is measured. Determine whether FANCL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5279
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX19A is perturbed and the expression of MRPL34 is measured. Does this perturbation cause a significant change in MRPL34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX19A is perturbed and the expression of MRPL34 is measured. Does this perturbation cause a significant change in MRPL34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11230
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GINS4 and examine the expression of CDKN1A. Does perturbing GINS4 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GINS4 and examine the expression of CDKN1A. Does perturbing GINS4 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17851
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRRM1 and then measure expression of SRRM1. Does this perturbation cause a significant change in SRRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRRM1 and then measure expression of SRRM1. Does this perturbation cause a significant change in SRRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51274
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DPH2 is perturbed and EIF4E expression is measured. Determine whether EIF4E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DPH2 is perturbed and EIF4E expression is measured. Determine whether EIF4E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12989
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD3 and examine the expression of PPP1CA. Does perturbing CHCHD3 lead to a significant change in PPP1CA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD3 and examine the expression of PPP1CA. Does perturbing CHCHD3 lead to a significant change in PPP1CA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7271
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHMP2A, does the expression profile of WDR34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHMP2A, does the expression profile of WDR34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7457
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSTK is associated with a significant change in PYURF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSTK is associated with a significant change in PYURF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40215
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC10 and then measure expression of CENPH. Does this perturbation cause a significant change in CENPH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC10 and then measure expression of CENPH. Does this perturbation cause a significant change in CENPH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16014
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CXXC1 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CXXC1 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10459
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHX37 is perturbed and the expression of OIP5 is measured. Determine whether OIP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHX37 is perturbed and the expression of OIP5 is measured. Determine whether OIP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12226
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIS18BP1 and then measure expression of MCM2. Does this perturbation cause a significant change in MCM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIS18BP1 and then measure expression of MCM2. Does this perturbation cause a significant change in MCM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26464
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XPO1 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XPO1 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60385
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HCFC1 is associated with a significant change in RAB27A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HCFC1 is associated with a significant change in RAB27A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19745
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHCTF1 is perturbed and CD99 expression is observed. Does this perturbation lead to a significant difference in CD99 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHCTF1 is perturbed and CD99 expression is observed. Does this perturbation lead to a significant difference in CD99 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":973
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHMP4B is perturbed and UGGT1 expression is observed. Does this perturbation lead to a significant difference in UGGT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHMP4B is perturbed and UGGT1 expression is observed. Does this perturbation lead to a significant difference in UGGT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7513
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CPOX is perturbed and the expression of CPOX is measured. Does this perturbation cause a significant change in CPOX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CPOX is perturbed and the expression of CPOX is measured. Does this perturbation cause a significant change in CPOX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9530
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNTTIP2 and examine the expression of NDC80. Does perturbing DNTTIP2 lead to a significant change in NDC80 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNTTIP2 and examine the expression of NDC80. Does perturbing DNTTIP2 lead to a significant change in NDC80 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12821
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB4 and monitor KLF16 expression. Decide whether this perturbation leads to a significant alteration in KLF16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB4 and monitor KLF16 expression. Decide whether this perturbation leads to a significant alteration in KLF16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61028
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RBM39 and monitor TMSB15A expression. Decide whether this perturbation leads to a significant alteration in TMSB15A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RBM39 and monitor TMSB15A expression. Decide whether this perturbation leads to a significant alteration in TMSB15A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41728
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELOVL1 is perturbed and ELOVL1 expression is quantified. Does this perturbation result in a significant change in ELOVL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELOVL1 is perturbed and ELOVL1 expression is quantified. Does this perturbation result in a significant change in ELOVL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15042
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3H and examine the expression of TRMT6. Does perturbing EIF3H lead to a significant change in TRMT6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3H and examine the expression of TRMT6. Does perturbing EIF3H lead to a significant change in TRMT6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14471
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UTP6 is perturbed and the expression of NCAPH is measured. Determine whether NCAPH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UTP6 is perturbed and the expression of NCAPH is measured. Determine whether NCAPH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58696
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP1R12A is perturbed and MAST2 expression is measured. Determine whether MAST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP1R12A is perturbed and MAST2 expression is measured. Determine whether MAST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37819
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHTF18 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHTF18 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7653
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WAC, does the expression profile of CCBE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WAC, does the expression profile of CCBE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59327
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LETM1 is perturbed and the expression of NUPR1 is measured. Does this perturbation cause a significant change in NUPR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LETM1 is perturbed and the expression of NUPR1 is measured. Does this perturbation cause a significant change in NUPR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23850
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM4 is perturbed and the expression of MRPL10 is measured. Determine whether MRPL10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM4 is perturbed and the expression of MRPL10 is measured. Determine whether MRPL10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38306
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KTI12 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KTI12 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23483
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TEN1 is associated with a significant change in TFAM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TEN1 is associated with a significant change in TFAM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53455
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SMC5 is perturbed and the expression of ERCC6L is measured. Does this perturbation cause a significant change in ERCC6L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SMC5 is perturbed and the expression of ERCC6L is measured. Does this perturbation cause a significant change in ERCC6L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49220
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1B2 and examine the expression of HMGCS1. Does perturbing ATP6V1B2 lead to a significant change in HMGCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1B2 and examine the expression of HMGCS1. Does perturbing ATP6V1B2 lead to a significant change in HMGCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2881
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNL2 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNL2 is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18159
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR5 is perturbed and the expression of CHMP4C is measured. Determine whether CHMP4C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR5 is perturbed and the expression of CHMP4C is measured. Determine whether CHMP4C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59906
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRA2B and then measure expression of S100A10. Does this perturbation cause a significant change in S100A10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRA2B and then measure expression of S100A10. Does this perturbation cause a significant change in S100A10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55444
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD3 is perturbed and FGFRL1 expression is observed. Does this perturbation lead to a significant difference in FGFRL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD3 is perturbed and FGFRL1 expression is observed. Does this perturbation lead to a significant difference in FGFRL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39863
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCAP and then measure expression of SCAP. Does this perturbation cause a significant change in SCAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCAP and then measure expression of SCAP. Does this perturbation cause a significant change in SCAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46964
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LSM4, does the expression profile of DNMT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LSM4, does the expression profile of DNMT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24267
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb WDR61 and monitor WDR61 expression. Decide whether this perturbation leads to a significant alteration in WDR61 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb WDR61 and monitor WDR61 expression. Decide whether this perturbation leads to a significant alteration in WDR61 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59978
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC25A3 is perturbed and HSF2 expression is quantified. Does this perturbation result in a significant change in HSF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC25A3 is perturbed and HSF2 expression is quantified. Does this perturbation result in a significant change in HSF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48642
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS4X is perturbed and the expression of CCNB2 is measured. Determine whether CCNB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS4X is perturbed and the expression of CCNB2 is measured. Determine whether CCNB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45676
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C9orf16 is associated with a significant change in C9orf16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C9orf16 is associated with a significant change in C9orf16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4685
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CASP8AP2 and then measure expression of GTPBP10. Does this perturbation cause a significant change in GTPBP10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CASP8AP2 and then measure expression of GTPBP10. Does this perturbation cause a significant change in GTPBP10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5034
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of DNAJC19. Does this perturbation cause a significant change in DNAJC19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of DNAJC19. Does this perturbation cause a significant change in DNAJC19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12604
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIN is perturbed and the expression of ARMC6 is measured. Does this perturbation cause a significant change in ARMC6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIN is perturbed and the expression of ARMC6 is measured. Does this perturbation cause a significant change in ARMC6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23190
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS6 and then measure expression of DNAJC16. Does this perturbation cause a significant change in DNAJC16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS6 and then measure expression of DNAJC16. Does this perturbation cause a significant change in DNAJC16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22034
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb INO80C and monitor INO80C expression. Decide whether this perturbation leads to a significant alteration in INO80C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb INO80C and monitor INO80C expression. Decide whether this perturbation leads to a significant alteration in INO80C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21608
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HECTD1 and monitor ISOC1 expression. Decide whether this perturbation leads to a significant alteration in ISOC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HECTD1 and monitor ISOC1 expression. Decide whether this perturbation leads to a significant alteration in ISOC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19888
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOC3L is perturbed and KIF20A expression is observed. Does this perturbation lead to a significant difference in KIF20A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOC3L is perturbed and KIF20A expression is observed. Does this perturbation lead to a significant difference in KIF20A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31793
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLG is perturbed and ADORA2B expression is quantified. Does this perturbation result in a significant change in ADORA2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLG is perturbed and ADORA2B expression is quantified. Does this perturbation result in a significant change in ADORA2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36402
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC2 and then measure expression of NCAPH. Does this perturbation cause a significant change in NCAPH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC2 and then measure expression of NCAPH. Does this perturbation cause a significant change in NCAPH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39524
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KDM2A is perturbed and KDM2A expression is quantified. Does this perturbation result in a significant change in KDM2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KDM2A is perturbed and KDM2A expression is quantified. Does this perturbation result in a significant change in KDM2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22882
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FBXO42 is perturbed and the expression of HCFC1R1 is measured. Determine whether HCFC1R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FBXO42 is perturbed and the expression of HCFC1R1 is measured. Determine whether HCFC1R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16726
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb INTS2 and monitor ARHGAP19 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb INTS2 and monitor ARHGAP19 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21928
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BTAF1 is perturbed and ERCC6 expression is observed. Does this perturbation lead to a significant difference in ERCC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BTAF1 is perturbed and ERCC6 expression is observed. Does this perturbation lead to a significant difference in ERCC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4103
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCLAF1, does the expression profile of TNK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCLAF1, does the expression profile of TNK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3467
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COX17 and examine the expression of MGST1. Does perturbing COX17 lead to a significant change in MGST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COX17 and examine the expression of MGST1. Does perturbing COX17 lead to a significant change in MGST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9281
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOE1 and then measure expression of HCFC1R1. Does this perturbation cause a significant change in HCFC1R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOE1 and then measure expression of HCFC1R1. Does this perturbation cause a significant change in HCFC1R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54914
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COMTD1 is perturbed and HNRNPA1 expression is observed. Does this perturbation lead to a significant difference in HNRNPA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COMTD1 is perturbed and HNRNPA1 expression is observed. Does this perturbation lead to a significant difference in HNRNPA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8673
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL13 is perturbed and the expression of CDCA7 is measured. Does this perturbation cause a significant change in CDCA7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL13 is perturbed and the expression of CDCA7 is measured. Does this perturbation cause a significant change in CDCA7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43420
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MBD3 and monitor MBD3 expression. Decide whether this perturbation leads to a significant alteration in MBD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MBD3 and monitor MBD3 expression. Decide whether this perturbation leads to a significant alteration in MBD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24848
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NACA and examine the expression of FAM83D. Does perturbing NACA lead to a significant change in FAM83D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NACA and examine the expression of FAM83D. Does perturbing NACA lead to a significant change in FAM83D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29711
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOSC8 is perturbed and KIF15 expression is quantified. Does this perturbation result in a significant change in KIF15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOSC8 is perturbed and KIF15 expression is quantified. Does this perturbation result in a significant change in KIF15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16172
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CASP8AP2 and examine the expression of CDCA7. Does perturbing CASP8AP2 lead to a significant change in CDCA7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CASP8AP2 and examine the expression of CDCA7. Does perturbing CASP8AP2 lead to a significant change in CDCA7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5021
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of CCN3. Does perturbing PSMD4 lead to a significant change in CCN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of CCN3. Does perturbing PSMD4 lead to a significant change in CCN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39881
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UCHL5 is perturbed and the expression of RO60 is measured. Determine whether RO60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UCHL5 is perturbed and the expression of RO60 is measured. Determine whether RO60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57586
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPS17 and monitor RBL1 expression. Decide whether this perturbation leads to a significant alteration in RBL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPS17 and monitor RBL1 expression. Decide whether this perturbation leads to a significant alteration in RBL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45168
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP6V1B2 is perturbed and SCD expression is quantified. Does this perturbation result in a significant change in SCD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP6V1B2 is perturbed and SCD expression is quantified. Does this perturbation result in a significant change in SCD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2902
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DCTN3 is perturbed and the expression of DCTN3 is measured. Does this perturbation cause a significant change in DCTN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DCTN3 is perturbed and the expression of DCTN3 is measured. Does this perturbation cause a significant change in DCTN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10860
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MBTPS2 is perturbed and MEG3 expression is observed. Does this perturbation lead to a significant difference in MEG3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MBTPS2 is perturbed and MEG3 expression is observed. Does this perturbation lead to a significant difference in MEG3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24973
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IRF2BP2 and monitor SFRP1 expression. Decide whether this perturbation leads to a significant alteration in SFRP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IRF2BP2 and monitor SFRP1 expression. Decide whether this perturbation leads to a significant alteration in SFRP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22248
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3B2 and examine the expression of CCHCR1. Does perturbing SF3B2 lead to a significant change in CCHCR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3B2 and examine the expression of CCHCR1. Does perturbing SF3B2 lead to a significant change in CCHCR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48011
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DSTYK and monitor EMP3 expression. Decide whether this perturbation leads to a significant alteration in EMP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DSTYK and monitor EMP3 expression. Decide whether this perturbation leads to a significant alteration in EMP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13288
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RRN3, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RRN3, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45997
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLE is perturbed and PARPBP expression is observed. Does this perturbation lead to a significant difference in PARPBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLE is perturbed and PARPBP expression is observed. Does this perturbation lead to a significant difference in PARPBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36333
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRC1 is perturbed and CDCA3 expression is observed. Does this perturbation lead to a significant difference in CDCA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRC1 is perturbed and CDCA3 expression is observed. Does this perturbation lead to a significant difference in CDCA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38273
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STRAP is perturbed and PLK4 expression is quantified. Does this perturbation result in a significant change in PLK4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STRAP is perturbed and PLK4 expression is quantified. Does this perturbation result in a significant change in PLK4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51822
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPC and monitor DDIT3 expression. Decide whether this perturbation leads to a significant alteration in DDIT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPC and monitor DDIT3 expression. Decide whether this perturbation leads to a significant alteration in DDIT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20388
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPMT1 is perturbed and DBN1 expression is observed. Does this perturbation lead to a significant difference in DBN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPMT1 is perturbed and DBN1 expression is observed. Does this perturbation lead to a significant difference in DBN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40383
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMC6 is associated with a significant change in SMC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMC6 is associated with a significant change in SMC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49245
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC11 is perturbed and CXCL8 expression is measured. Determine whether CXCL8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC11 is perturbed and CXCL8 expression is measured. Determine whether CXCL8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55529
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNF168 is perturbed and RNF168 expression is measured. Determine whether RNF168 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNF168 is perturbed and RNF168 expression is measured. Determine whether RNF168 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42669
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QRSL1 and examine the expression of MT-ND2. Does perturbing QRSL1 lead to a significant change in MT-ND2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QRSL1 and examine the expression of MT-ND2. Does perturbing QRSL1 lead to a significant change in MT-ND2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40711
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IMPA2 is perturbed and FOXJ2 expression is measured. Determine whether FOXJ2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IMPA2 is perturbed and FOXJ2 expression is measured. Determine whether FOXJ2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21439
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX52 is associated with a significant change in CDC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX52 is associated with a significant change in CDC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11615
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDAP1 is perturbed and the expression of PDAP1 is measured. Does this perturbation cause a significant change in PDAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDAP1 is perturbed and the expression of PDAP1 is measured. Does this perturbation cause a significant change in PDAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34440
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNX15 is perturbed and C8orf88 expression is quantified. Does this perturbation result in a significant change in C8orf88 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNX15 is perturbed and C8orf88 expression is quantified. Does this perturbation result in a significant change in C8orf88 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50362
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CMTR2 and examine the expression of ESCO2. Does perturbing CMTR2 lead to a significant change in ESCO2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CMTR2 and examine the expression of ESCO2. Does perturbing CMTR2 lead to a significant change in ESCO2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8171
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRMT6 is perturbed and the expression of PCMT1 is measured. Determine whether PCMT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRMT6 is perturbed and the expression of PCMT1 is measured. Determine whether PCMT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55776
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1D is perturbed and the expression of ATP6V1D is measured. Does this perturbation cause a significant change in ATP6V1D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1D is perturbed and the expression of ATP6V1D is measured. Does this perturbation cause a significant change in ATP6V1D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2940
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUVBL1 and examine the expression of STMN1. Does perturbing RUVBL1 lead to a significant change in STMN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUVBL1 and examine the expression of STMN1. Does perturbing RUVBL1 lead to a significant change in STMN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46411
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR1E, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR1E, does the expression profile of PCLAF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36587
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SUGP1 and monitor BRIP1 expression. Decide whether this perturbation leads to a significant alteration in BRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SUGP1 and monitor BRIP1 expression. Decide whether this perturbation leads to a significant alteration in BRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52048
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD9 is perturbed and UCKL1 expression is observed. Does this perturbation lead to a significant difference in UCKL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD9 is perturbed and UCKL1 expression is observed. Does this perturbation lead to a significant difference in UCKL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40013
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb METTL3 and monitor PLEKHO1 expression. Decide whether this perturbation leads to a significant alteration in PLEKHO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb METTL3 and monitor PLEKHO1 expression. Decide whether this perturbation leads to a significant alteration in PLEKHO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26198
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AAAS is perturbed and the expression of SUFU is measured. Does this perturbation cause a significant change in SUFU expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AAAS is perturbed and the expression of SUFU is measured. Does this perturbation cause a significant change in SUFU expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EMC1 is perturbed and the expression of NEK2 is measured. Determine whether NEK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EMC1 is perturbed and the expression of NEK2 is measured. Determine whether NEK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15236
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TIMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TIMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11057
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CYFIP1, does the expression profile of SEC23B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CYFIP1, does the expression profile of SEC23B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10557
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ROMO1, does the expression profile of DAG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ROMO1, does the expression profile of DAG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42977
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPAT and then measure expression of SSBP4. Does this perturbation cause a significant change in SSBP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPAT and then measure expression of SSBP4. Does this perturbation cause a significant change in SSBP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18264
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of DDIT3 is measured. Determine whether DDIT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of DDIT3 is measured. Determine whether DDIT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40686
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, THOC6 is perturbed and the expression of TNFRSF12A is measured. Determine whether TNFRSF12A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, THOC6 is perturbed and the expression of TNFRSF12A is measured. Determine whether TNFRSF12A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53986
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35A4 is associated with a significant change in FANCA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35A4 is associated with a significant change in FANCA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48705
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGS1 and then measure expression of HIST1H1D. Does this perturbation cause a significant change in HIST1H1D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGS1 and then measure expression of HIST1H1D. Does this perturbation cause a significant change in HIST1H1D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53734
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUP133 and then measure expression of SELENOM. Does this perturbation cause a significant change in SELENOM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUP133 and then measure expression of SELENOM. Does this perturbation cause a significant change in SELENOM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33044
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USF2, does the expression profile of NENF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USF2, does the expression profile of NENF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58197
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GART is perturbed and the expression of HEATR6 is measured. Determine whether HEATR6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GART is perturbed and the expression of HEATR6 is measured. Determine whether HEATR6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17396
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PREB and monitor CENPV expression. Decide whether this perturbation leads to a significant alteration in CENPV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PREB and monitor CENPV expression. Decide whether this perturbation leads to a significant alteration in CENPV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38368
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TEN1 and then measure expression of TFAM. Does this perturbation cause a significant change in TFAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TEN1 and then measure expression of TFAM. Does this perturbation cause a significant change in TFAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53454
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SMG5 and monitor EPB41L4A-AS1 expression. Decide whether this perturbation leads to a significant alteration in EPB41L4A-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SMG5 and monitor EPB41L4A-AS1 expression. Decide whether this perturbation leads to a significant alteration in EPB41L4A-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49308
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PET117 and then measure expression of NAT14. Does this perturbation cause a significant change in NAT14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PET117 and then measure expression of NAT14. Does this perturbation cause a significant change in NAT14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34884
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRNP25 is perturbed and the expression of SETD1A is measured. Determine whether SETD1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRNP25 is perturbed and the expression of SETD1A is measured. Determine whether SETD1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49796
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SERF2 is associated with a significant change in FAM111B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SERF2 is associated with a significant change in FAM111B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47645
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RABGGTB is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RABGGTB is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40912
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GINS1 is perturbed and the expression of EID1 is measured. Determine whether EID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GINS1 is perturbed and the expression of EID1 is measured. Determine whether EID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17816
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SCD and monitor ITM2B expression. Decide whether this perturbation leads to a significant alteration in ITM2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SCD and monitor ITM2B expression. Decide whether this perturbation leads to a significant alteration in ITM2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47008
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UQCRC2 is perturbed and the expression of G0S2 is measured. Determine whether G0S2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UQCRC2 is perturbed and the expression of G0S2 is measured. Determine whether G0S2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57946
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb VPS35 and monitor PCLAF expression. Decide whether this perturbation leads to a significant alteration in PCLAF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb VPS35 and monitor PCLAF expression. Decide whether this perturbation leads to a significant alteration in PCLAF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59148
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COX15 and monitor RAB34 expression. Decide whether this perturbation leads to a significant alteration in RAB34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COX15 and monitor RAB34 expression. Decide whether this perturbation leads to a significant alteration in RAB34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9268
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GUCD1, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GUCD1, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19327
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPC25 is associated with a significant change in MKI67 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPC25 is associated with a significant change in MKI67 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50665
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of IARS2 is measured. Determine whether IARS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of IARS2 is measured. Determine whether IARS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21156
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AIFM1 and then measure expression of MIEN1. Does this perturbation cause a significant change in MIEN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AIFM1 and then measure expression of MIEN1. Does this perturbation cause a significant change in MIEN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1044
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPIA is perturbed and CST3 expression is observed. Does this perturbation lead to a significant difference in CST3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPIA is perturbed and CST3 expression is observed. Does this perturbation lead to a significant difference in CST3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37483
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR54 is perturbed and WDR54 expression is quantified. Does this perturbation result in a significant change in WDR54 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR54 is perturbed and WDR54 expression is quantified. Does this perturbation result in a significant change in WDR54 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59912
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEN1 and then measure expression of PLOD1. Does this perturbation cause a significant change in PLOD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEN1 and then measure expression of PLOD1. Does this perturbation cause a significant change in PLOD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25894
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor DCUN1D1 expression. Decide whether this perturbation leads to a significant alteration in DCUN1D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor DCUN1D1 expression. Decide whether this perturbation leads to a significant alteration in DCUN1D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47368
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GPS1 is perturbed and PCLAF expression is observed. Does this perturbation lead to a significant difference in PCLAF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GPS1 is perturbed and PCLAF expression is observed. Does this perturbation lead to a significant difference in PCLAF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18523
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, URI1 is perturbed and CDC25A expression is quantified. Does this perturbation result in a significant change in CDC25A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, URI1 is perturbed and CDC25A expression is quantified. Does this perturbation result in a significant change in CDC25A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58092
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LSM7, does the expression profile of TUBB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LSM7, does the expression profile of TUBB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24357
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GRB2, does the expression profile of GRB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GRB2, does the expression profile of GRB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18587
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SUPT5H and monitor LBR expression. Decide whether this perturbation leads to a significant alteration in LBR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SUPT5H and monitor LBR expression. Decide whether this perturbation leads to a significant alteration in LBR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52228
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNOT10, does the expression profile of FHL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNOT10, does the expression profile of FHL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8297
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ADRM1 is perturbed and the expression of ADRM1 is measured. Does this perturbation cause a significant change in ADRM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ADRM1 is perturbed and the expression of ADRM1 is measured. Does this perturbation cause a significant change in ADRM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":840
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL13 is perturbed and PPRC1 expression is quantified. Does this perturbation result in a significant change in PPRC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL13 is perturbed and PPRC1 expression is quantified. Does this perturbation result in a significant change in PPRC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27002
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NBEAL1 and then measure expression of MEF2D. Does this perturbation cause a significant change in MEF2D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NBEAL1 and then measure expression of MEF2D. Does this perturbation cause a significant change in MEF2D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30024
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS13 and then measure expression of PCLAF. Does this perturbation cause a significant change in PCLAF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS13 and then measure expression of PCLAF. Does this perturbation cause a significant change in PCLAF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45044
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2F2 is perturbed and BLM expression is measured. Determine whether BLM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2F2 is perturbed and BLM expression is measured. Determine whether BLM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18959
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POP5 and monitor METTL21A expression. Decide whether this perturbation leads to a significant alteration in METTL21A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POP5 and monitor METTL21A expression. Decide whether this perturbation leads to a significant alteration in METTL21A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37318
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and SLC3A2 expression is measured. Determine whether SLC3A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and SLC3A2 expression is measured. Determine whether SLC3A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50729
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LENG8 and examine the expression of SNHG21. Does perturbing LENG8 lead to a significant change in SNHG21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LENG8 and examine the expression of SNHG21. Does perturbing LENG8 lead to a significant change in SNHG21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23811
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PFDN5 is perturbed and the expression of TMSB15A is measured. Determine whether TMSB15A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PFDN5 is perturbed and the expression of TMSB15A is measured. Determine whether TMSB15A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35056
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NOC2L is perturbed and BRCA1 expression is quantified. Does this perturbation result in a significant change in BRCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NOC2L is perturbed and BRCA1 expression is quantified. Does this perturbation result in a significant change in BRCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31762
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SUPT16H is perturbed and the expression of FAM111B is measured. Does this perturbation cause a significant change in FAM111B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SUPT16H is perturbed and the expression of FAM111B is measured. Does this perturbation cause a significant change in FAM111B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52120
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNRNP40 and examine the expression of SNRNP40. Does perturbing SNRNP40 lead to a significant change in SNRNP40 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNRNP40 and examine the expression of SNRNP40. Does perturbing SNRNP40 lead to a significant change in SNRNP40 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49861
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERCC3 is associated with a significant change in MCM10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERCC3 is associated with a significant change in MCM10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15555
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF236 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF236 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61503
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC1 and examine the expression of DDIT3. Does perturbing PSMC1 lead to a significant change in DDIT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC1 and examine the expression of DDIT3. Does perturbing PSMC1 lead to a significant change in DDIT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39481
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHODH and then measure expression of MTAP. Does this perturbation cause a significant change in MTAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHODH and then measure expression of MTAP. Does this perturbation cause a significant change in MTAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11974
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS27 and examine the expression of IGFBP6. Does perturbing RPS27 lead to a significant change in IGFBP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS27 and examine the expression of IGFBP6. Does perturbing RPS27 lead to a significant change in IGFBP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45491
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INO80B is associated with a significant change in DTYMK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INO80B is associated with a significant change in DTYMK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21585
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GRB2 and examine the expression of GRB2. Does perturbing GRB2 lead to a significant change in GRB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GRB2 and examine the expression of GRB2. Does perturbing GRB2 lead to a significant change in GRB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18581
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TRRAP and monitor PSAT1 expression. Decide whether this perturbation leads to a significant alteration in PSAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TRRAP and monitor PSAT1 expression. Decide whether this perturbation leads to a significant alteration in PSAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55898
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PNKP is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PNKP is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36009
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBE2I and monitor UBE2I expression. Decide whether this perturbation leads to a significant alteration in UBE2I expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBE2I and monitor UBE2I expression. Decide whether this perturbation leads to a significant alteration in UBE2I expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57248
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMELESS is associated with a significant change in TRIP13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMELESS is associated with a significant change in TRIP13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54105
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEF1G and examine the expression of EEF1G. Does perturbing EEF1G lead to a significant change in EEF1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEF1G and examine the expression of EEF1G. Does perturbing EEF1G lead to a significant change in EEF1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13771
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM199 is associated with a significant change in TMEM199 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM199 is associated with a significant change in TMEM199 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54665
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V0C is perturbed and MSMO1 expression is observed. Does this perturbation lead to a significant difference in MSMO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V0C is perturbed and MSMO1 expression is observed. Does this perturbation lead to a significant difference in MSMO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2813
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PIK3R4 is perturbed and RTTN expression is quantified. Does this perturbation result in a significant change in RTTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PIK3R4 is perturbed and RTTN expression is quantified. Does this perturbation result in a significant change in RTTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35662
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NASP is perturbed and the expression of KRT81 is measured. Determine whether KRT81 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NASP is perturbed and the expression of KRT81 is measured. Determine whether KRT81 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29956
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NRDE2 is perturbed and the expression of SYNE2 is measured. Does this perturbation cause a significant change in SYNE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NRDE2 is perturbed and the expression of SYNE2 is measured. Does this perturbation cause a significant change in SYNE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32480
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHX37 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHX37 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12233
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLE is associated with a significant change in PARPBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLE is associated with a significant change in PARPBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36335
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP2CA is perturbed and ACTA2 expression is measured. Determine whether ACTA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP2CA is perturbed and ACTA2 expression is measured. Determine whether ACTA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38009
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOLC1 is perturbed and the expression of HIST1H2AH is measured. Determine whether HIST1H2AH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOLC1 is perturbed and the expression of HIST1H2AH is measured. Determine whether HIST1H2AH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32066
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS2 is perturbed and the expression of PRPF19 is measured. Does this perturbation cause a significant change in PRPF19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS2 is perturbed and the expression of PRPF19 is measured. Does this perturbation cause a significant change in PRPF19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19540
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLRG1 and examine the expression of CDKN1A. Does perturbing PLRG1 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLRG1 and examine the expression of CDKN1A. Does perturbing PLRG1 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35851
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETD2 and then measure expression of KRT7. Does this perturbation cause a significant change in KRT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETD2 and then measure expression of KRT7. Does this perturbation cause a significant change in KRT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47754
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL16 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL16 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27118
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3C2 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3C2 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19164
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM127 is perturbed and TMEM141 expression is measured. Determine whether TMEM141 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM127 is perturbed and TMEM141 expression is measured. Determine whether TMEM141 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54619
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF8 is perturbed and the expression of DANCR is measured. Does this perturbation cause a significant change in DANCR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF8 is perturbed and the expression of DANCR is measured. Does this perturbation cause a significant change in DANCR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52870
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ALYREF and examine the expression of RABEPK. Does perturbing ALYREF lead to a significant change in RABEPK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ALYREF and examine the expression of RABEPK. Does perturbing ALYREF lead to a significant change in RABEPK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1251
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ACTR1B is perturbed and COX4I1 expression is observed. Does this perturbation lead to a significant difference in COX4I1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ACTR1B is perturbed and COX4I1 expression is observed. Does this perturbation lead to a significant difference in COX4I1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":643
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS37A and then measure expression of VPS37A. Does this perturbation cause a significant change in VPS37A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS37A and then measure expression of VPS37A. Does this perturbation cause a significant change in VPS37A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59174
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TOPBP1 and examine the expression of FIGNL1. Does perturbing TOPBP1 lead to a significant change in FIGNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TOPBP1 and examine the expression of FIGNL1. Does perturbing TOPBP1 lead to a significant change in FIGNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55121
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COQ2 is perturbed and COQ2 expression is quantified. Does this perturbation result in a significant change in COQ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COQ2 is perturbed and COQ2 expression is quantified. Does this perturbation result in a significant change in COQ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9072
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRTO4, does the expression profile of POLA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRTO4, does the expression profile of POLA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28927
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPDL is associated with a significant change in LMNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPDL is associated with a significant change in LMNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20415
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SART1 and monitor CENPW expression. Decide whether this perturbation leads to a significant alteration in CENPW expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SART1 and monitor CENPW expression. Decide whether this perturbation leads to a significant alteration in CENPW expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46778
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR2I is perturbed and the expression of PDLIM7 is measured. Does this perturbation cause a significant change in PDLIM7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR2I is perturbed and the expression of PDLIM7 is measured. Does this perturbation cause a significant change in PDLIM7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36860
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HMGA1 is perturbed and the expression of FKRP is measured. Determine whether FKRP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HMGA1 is perturbed and the expression of FKRP is measured. Determine whether FKRP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20186
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF3C5, does the expression profile of GMNN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF3C5, does the expression profile of GMNN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19257
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PYROXD1 and monitor NUPR1 expression. Decide whether this perturbation leads to a significant alteration in NUPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PYROXD1 and monitor NUPR1 expression. Decide whether this perturbation leads to a significant alteration in NUPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40638
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EBNA1BP2 is perturbed and the expression of SGO1 is measured. Determine whether SGO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EBNA1BP2 is perturbed and the expression of SGO1 is measured. Determine whether SGO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13616
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb INTS11 and monitor PBK expression. Decide whether this perturbation leads to a significant alteration in PBK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb INTS11 and monitor PBK expression. Decide whether this perturbation leads to a significant alteration in PBK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21798
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF718 is perturbed and MSN expression is quantified. Does this perturbation result in a significant change in MSN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF718 is perturbed and MSN expression is quantified. Does this perturbation result in a significant change in MSN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61702
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUTF2 is perturbed and the expression of STMN1 is measured. Does this perturbation cause a significant change in STMN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUTF2 is perturbed and the expression of STMN1 is measured. Does this perturbation cause a significant change in STMN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33470
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2L is perturbed and CEP192 expression is quantified. Does this perturbation result in a significant change in CEP192 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2L is perturbed and CEP192 expression is quantified. Does this perturbation result in a significant change in CEP192 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36902
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAT2A is associated with a significant change in CHRAC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAT2A is associated with a significant change in CHRAC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24775
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and HSP90B1 expression is observed. Does this perturbation lead to a significant difference in HSP90B1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and HSP90B1 expression is observed. Does this perturbation lead to a significant difference in HSP90B1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2203
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FASTKD5 is perturbed and the expression of MT-CO1 is measured. Determine whether MT-CO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FASTKD5 is perturbed and the expression of MT-CO1 is measured. Determine whether MT-CO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16576
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2H is associated with a significant change in RPA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2H is associated with a significant change in RPA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36815
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IPO9, does the expression profile of IPO9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IPO9, does the expression profile of IPO9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22207
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LSM12 and monitor LSM12 expression. Decide whether this perturbation leads to a significant alteration in LSM12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LSM12 and monitor LSM12 expression. Decide whether this perturbation leads to a significant alteration in LSM12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24158
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSCB is associated with a significant change in MCM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSCB is associated with a significant change in MCM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20655
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FTSJ3 is associated with a significant change in MYBL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FTSJ3 is associated with a significant change in MYBL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17085
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PCBP1 is associated with a significant change in PCBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PCBP1 is associated with a significant change in PCBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34235
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RSL1D1 and then measure expression of MRPS6. Does this perturbation cause a significant change in MRPS6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RSL1D1 and then measure expression of MRPS6. Does this perturbation cause a significant change in MRPS6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46224
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS14, does the expression profile of RRM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS14, does the expression profile of RRM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45087
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PCNA is perturbed and CDCA7 expression is observed. Does this perturbation lead to a significant difference in CDCA7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PCNA is perturbed and CDCA7 expression is observed. Does this perturbation lead to a significant difference in CDCA7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34403
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TWISTNB is perturbed and MAPK9 expression is measured. Determine whether MAPK9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TWISTNB is perturbed and MAPK9 expression is measured. Determine whether MAPK9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56719
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MLST8 and examine the expression of ZHX3. Does perturbing MLST8 lead to a significant change in ZHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MLST8 and examine the expression of ZHX3. Does perturbing MLST8 lead to a significant change in ZHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26571
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COX10 and monitor COX10 expression. Decide whether this perturbation leads to a significant alteration in COX10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COX10 and monitor COX10 expression. Decide whether this perturbation leads to a significant alteration in COX10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9208
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LAMB1, does the expression profile of NUSAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LAMB1, does the expression profile of NUSAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23537
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CD3EAP and examine the expression of CD3EAP. Does perturbing CD3EAP lead to a significant change in CD3EAP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CD3EAP and examine the expression of CD3EAP. Does perturbing CD3EAP lead to a significant change in CD3EAP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5961
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAXX is perturbed and TXNRD1 expression is measured. Determine whether TXNRD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAXX is perturbed and TXNRD1 expression is measured. Determine whether TXNRD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10699
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COQ5, does the expression profile of FARP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COQ5, does the expression profile of FARP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9147
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX5A and then measure expression of COX5A. Does this perturbation cause a significant change in COX5A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX5A and then measure expression of COX5A. Does this perturbation cause a significant change in COX5A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9304
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCNA and examine the expression of SPAG5. Does perturbing PCNA lead to a significant change in SPAG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCNA and examine the expression of SPAG5. Does perturbing PCNA lead to a significant change in SPAG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34381
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CRKL is perturbed and the expression of NRK is measured. Determine whether NRK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CRKL is perturbed and the expression of NRK is measured. Determine whether NRK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9726
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VPS37A, does the expression profile of PHF19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VPS37A, does the expression profile of PHF19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59187
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GINS2 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GINS2 is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17826
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM242, does the expression profile of DUT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM242, does the expression profile of DUT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54737
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of NUPR1. Does perturbing TELO2 lead to a significant change in NUPR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of NUPR1. Does perturbing TELO2 lead to a significant change in NUPR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53401
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TACC3 is associated with a significant change in TMEM129 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TACC3 is associated with a significant change in TMEM129 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52425
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPG7 and then measure expression of SLC1A5. Does this perturbation cause a significant change in SLC1A5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPG7 and then measure expression of SLC1A5. Does this perturbation cause a significant change in SLC1A5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50814
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of HSP90B1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of HSP90B1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2207
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C17orf58 and then measure expression of C17orf58. Does this perturbation cause a significant change in C17orf58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C17orf58 and then measure expression of C17orf58. Does this perturbation cause a significant change in C17orf58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4394
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CENPH and then measure expression of DCAF12. Does this perturbation cause a significant change in DCAF12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CENPH and then measure expression of DCAF12. Does this perturbation cause a significant change in DCAF12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6794
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OGFOD1 is perturbed and TOE1 expression is quantified. Does this perturbation result in a significant change in TOE1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OGFOD1 is perturbed and TOE1 expression is quantified. Does this perturbation result in a significant change in TOE1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33542
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL22, does the expression profile of MT-ATP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL22, does the expression profile of MT-ATP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27317
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, URI1 is perturbed and the expression of URI1 is measured. Does this perturbation cause a significant change in URI1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, URI1 is perturbed and the expression of URI1 is measured. Does this perturbation cause a significant change in URI1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58080
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRNP27 and then measure expression of SNRNP27. Does this perturbation cause a significant change in SNRNP27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRNP27 and then measure expression of SNRNP27. Does this perturbation cause a significant change in SNRNP27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49804
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNF8 is associated with a significant change in RNF8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNF8 is associated with a significant change in RNF8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42815
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YAE1 is perturbed and the expression of TMEM99 is measured. Does this perturbation cause a significant change in TMEM99 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YAE1 is perturbed and the expression of TMEM99 is measured. Does this perturbation cause a significant change in TMEM99 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60600
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of DDIT4 is measured. Does this perturbation cause a significant change in DDIT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of DDIT4 is measured. Does this perturbation cause a significant change in DDIT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21170
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL55 is perturbed and MT-ND3 expression is observed. Does this perturbation lead to a significant difference in MT-ND3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL55 is perturbed and MT-ND3 expression is observed. Does this perturbation lead to a significant difference in MT-ND3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28073
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SART1 is perturbed and CENPW expression is observed. Does this perturbation lead to a significant difference in CENPW expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SART1 is perturbed and CENPW expression is observed. Does this perturbation lead to a significant difference in CENPW expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46773
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPA2 is perturbed and the expression of CCNA2 is measured. Does this perturbation cause a significant change in CCNA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPA2 is perturbed and the expression of CCNA2 is measured. Does this perturbation cause a significant change in CCNA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43040
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDCD2 is perturbed and ELK1 expression is measured. Determine whether ELK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDCD2 is perturbed and ELK1 expression is measured. Determine whether ELK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34519
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNRNP200 and monitor FKBP5 expression. Decide whether this perturbation leads to a significant alteration in FKBP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNRNP200 and monitor FKBP5 expression. Decide whether this perturbation leads to a significant alteration in FKBP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49748
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSBP is perturbed and the expression of CEP78 is measured. Does this perturbation cause a significant change in CEP78 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSBP is perturbed and the expression of CEP78 is measured. Does this perturbation cause a significant change in CEP78 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33830
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMG8 is perturbed and SMG8 expression is quantified. Does this perturbation result in a significant change in SMG8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMG8 is perturbed and SMG8 expression is quantified. Does this perturbation result in a significant change in SMG8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49392
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF1 and examine the expression of PSAT1. Does perturbing EIF1 lead to a significant change in PSAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF1 and examine the expression of PSAT1. Does perturbing EIF1 lead to a significant change in PSAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13991
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP14 and then measure expression of C21orf58. Does this perturbation cause a significant change in C21orf58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP14 and then measure expression of C21orf58. Does this perturbation cause a significant change in C21orf58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32154
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF8 and examine the expression of STMN1. Does perturbing PRPF8 lead to a significant change in STMN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF8 and examine the expression of STMN1. Does perturbing PRPF8 lead to a significant change in STMN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38981
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAE1, does the expression profile of PKMYT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RAE1, does the expression profile of PKMYT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41167
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NSMCE2, does the expression profile of CENPU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NSMCE2, does the expression profile of CENPU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32627
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRRM1 and then measure expression of LAMTOR4. Does this perturbation cause a significant change in LAMTOR4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRRM1 and then measure expression of LAMTOR4. Does this perturbation cause a significant change in LAMTOR4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51294
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDPK1, does the expression profile of LOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDPK1, does the expression profile of LOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34707
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTREX is perturbed and the expression of PTN is measured. Determine whether PTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTREX is perturbed and the expression of PTN is measured. Determine whether PTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29196
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL12 is associated with a significant change in PCLAF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL12 is associated with a significant change in PCLAF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43395
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CS is perturbed and TGM2 expression is quantified. Does this perturbation result in a significant change in TGM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CS is perturbed and TGM2 expression is quantified. Does this perturbation result in a significant change in TGM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9822
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of PSAT1 is measured. Does this perturbation cause a significant change in PSAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of PSAT1 is measured. Does this perturbation cause a significant change in PSAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4960
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPATA5 and monitor BLM expression. Decide whether this perturbation leads to a significant alteration in BLM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPATA5 and monitor BLM expression. Decide whether this perturbation leads to a significant alteration in BLM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50558
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FIP1L1, does the expression profile of MTR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FIP1L1, does the expression profile of MTR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16977
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UNC45A is perturbed and FANCG expression is quantified. Does this perturbation result in a significant change in FANCG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UNC45A is perturbed and FANCG expression is quantified. Does this perturbation result in a significant change in FANCG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57742
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL35 is perturbed and MT-ATP8 expression is measured. Determine whether MT-ATP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL35 is perturbed and MT-ATP8 expression is measured. Determine whether MT-ATP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27589
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL15, does the expression profile of PRR11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL15, does the expression profile of PRR11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43517
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CACNB3, does the expression profile of CACNB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CACNB3, does the expression profile of CACNB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4777
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBM25 is perturbed and SPAG5 expression is observed. Does this perturbation lead to a significant difference in SPAG5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBM25 is perturbed and SPAG5 expression is observed. Does this perturbation lead to a significant difference in SPAG5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41623
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GFM1 is perturbed and GFM1 expression is quantified. Does this perturbation result in a significant change in GFM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GFM1 is perturbed and GFM1 expression is quantified. Does this perturbation result in a significant change in GFM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17702
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUP160 is perturbed and the expression of SPC24 is measured. Does this perturbation cause a significant change in SPC24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUP160 is perturbed and the expression of SPC24 is measured. Does this perturbation cause a significant change in SPC24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33140
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL37A, does the expression profile of RPL37A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL37A, does the expression profile of RPL37A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44307
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPDL1 is perturbed and MCM7 expression is measured. Determine whether MCM7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPDL1 is perturbed and MCM7 expression is measured. Determine whether MCM7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50739
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TARS2 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TARS2 and monitor MT-ND3 expression. Decide whether this perturbation leads to a significant alteration in MT-ND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52998
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1 is perturbed and PDCD2L expression is measured. Determine whether PDCD2L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1 is perturbed and PDCD2L expression is measured. Determine whether PDCD2L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17929
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GPS2 and then measure expression of LARP6. Does this perturbation cause a significant change in LARP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GPS2 and then measure expression of LARP6. Does this perturbation cause a significant change in LARP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18564
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of IDH2. Does this perturbation cause a significant change in IDH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of IDH2. Does this perturbation cause a significant change in IDH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9034
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEP97 and monitor CEP97 expression. Decide whether this perturbation leads to a significant alteration in CEP97 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEP97 and monitor CEP97 expression. Decide whether this perturbation leads to a significant alteration in CEP97 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7058
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL36 and examine the expression of MT-ATP8. Does perturbing MRPL36 lead to a significant change in MT-ATP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL36 and examine the expression of MT-ATP8. Does perturbing MRPL36 lead to a significant change in MT-ATP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27621
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BOP1 is perturbed and the expression of TPX2 is measured. Determine whether TPX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BOP1 is perturbed and the expression of TPX2 is measured. Determine whether TPX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3756
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL34 is perturbed and MRPL34 expression is observed. Does this perturbation lead to a significant difference in MRPL34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL34 is perturbed and MRPL34 expression is observed. Does this perturbation lead to a significant difference in MRPL34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27543
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and DDOST expression is measured. Determine whether DDOST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and DDOST expression is measured. Determine whether DDOST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11049
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPA1 is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPA1 is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37406
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPA2 is perturbed and UBE2T expression is observed. Does this perturbation lead to a significant difference in UBE2T expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPA2 is perturbed and UBE2T expression is observed. Does this perturbation lead to a significant difference in UBE2T expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43033
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GSPT1 and monitor GSPT1 expression. Decide whether this perturbation leads to a significant alteration in GSPT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GSPT1 and monitor GSPT1 expression. Decide whether this perturbation leads to a significant alteration in GSPT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18728
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC17 and examine the expression of PRKDC. Does perturbing DNAJC17 lead to a significant change in PRKDC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC17 and examine the expression of PRKDC. Does perturbing DNAJC17 lead to a significant change in PRKDC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12571
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50675
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2A2 and then measure expression of GTF2A2. Does this perturbation cause a significant change in GTF2A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2A2 and then measure expression of GTF2A2. Does this perturbation cause a significant change in GTF2A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18784
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELOB and then measure expression of ELOB. Does this perturbation cause a significant change in ELOB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELOB and then measure expression of ELOB. Does this perturbation cause a significant change in ELOB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14974
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RTF1 and then measure expression of RUSC1. Does this perturbation cause a significant change in RUSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RTF1 and then measure expression of RUSC1. Does this perturbation cause a significant change in RUSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46344
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LTBP3 and then measure expression of LTBP3. Does this perturbation cause a significant change in LTBP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LTBP3 and then measure expression of LTBP3. Does this perturbation cause a significant change in LTBP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24364
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGS1 is perturbed and the expression of CLSPN is measured. Determine whether CLSPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGS1 is perturbed and the expression of CLSPN is measured. Determine whether CLSPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53756
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CD3EAP and examine the expression of NDC80. Does perturbing CD3EAP lead to a significant change in NDC80 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CD3EAP and examine the expression of NDC80. Does perturbing CD3EAP lead to a significant change in NDC80 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5951
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOSC5 is perturbed and the expression of MIRLET7BHG is measured. Determine whether MIRLET7BHG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOSC5 is perturbed and the expression of MIRLET7BHG is measured. Determine whether MIRLET7BHG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16126
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL3 and then measure expression of KIF4A. Does this perturbation cause a significant change in KIF4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL3 and then measure expression of KIF4A. Does this perturbation cause a significant change in KIF4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43964
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TPRKB is perturbed and TPRKB expression is measured. Determine whether TPRKB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TPRKB is perturbed and TPRKB expression is measured. Determine whether TPRKB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55369
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS2 is perturbed and the expression of AC100810.1 is measured. Determine whether AC100810.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS2 is perturbed and the expression of AC100810.1 is measured. Determine whether AC100810.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46766
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSNK1A1 is associated with a significant change in PIGX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSNK1A1 is associated with a significant change in PIGX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9915
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM127 and examine the expression of TMEM127. Does perturbing TMEM127 lead to a significant change in TMEM127 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM127 and examine the expression of TMEM127. Does perturbing TMEM127 lead to a significant change in TMEM127 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54601
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRSF6 and examine the expression of FAM200B. Does perturbing SRSF6 lead to a significant change in FAM200B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRSF6 and examine the expression of FAM200B. Does perturbing SRSF6 lead to a significant change in FAM200B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51531
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP53I13 is associated with a significant change in MRPL14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP53I13 is associated with a significant change in MRPL14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55205
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC7A5 is associated with a significant change in NINJ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC7A5 is associated with a significant change in NINJ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48895
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCT2 and then measure expression of DEPDC1. Does this perturbation cause a significant change in DEPDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCT2 and then measure expression of DEPDC1. Does this perturbation cause a significant change in DEPDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5704
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS2 is perturbed and TCEAL4 expression is quantified. Does this perturbation result in a significant change in TCEAL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS2 is perturbed and TCEAL4 expression is quantified. Does this perturbation result in a significant change in TCEAL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52982
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KRT8 and monitor KRT8 expression. Decide whether this perturbation leads to a significant alteration in KRT8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KRT8 and monitor KRT8 expression. Decide whether this perturbation leads to a significant alteration in KRT8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23448
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR83OS is perturbed and the expression of HMGN1 is measured. Determine whether HMGN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR83OS is perturbed and the expression of HMGN1 is measured. Determine whether HMGN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60176
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LSM3 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LSM3 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24223
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK1 is perturbed and SYNM expression is measured. Determine whether SYNM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK1 is perturbed and SYNM expression is measured. Determine whether SYNM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35799
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TEN1 and examine the expression of SLC1A5. Does perturbing TEN1 lead to a significant change in SLC1A5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TEN1 and examine the expression of SLC1A5. Does perturbing TEN1 lead to a significant change in SLC1A5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53431
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOL10 is perturbed and the expression of SNRPA is measured. Determine whether SNRPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOL10 is perturbed and the expression of SNRPA is measured. Determine whether SNRPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31836
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDC45 is perturbed and NMU expression is quantified. Does this perturbation result in a significant change in NMU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDC45 is perturbed and NMU expression is quantified. Does this perturbation result in a significant change in NMU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6242
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SFPQ and then measure expression of HPCAL1. Does this perturbation cause a significant change in HPCAL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SFPQ and then measure expression of HPCAL1. Does this perturbation cause a significant change in HPCAL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48134
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MPHOSPH6 is perturbed and the expression of MKI67 is measured. Determine whether MKI67 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MPHOSPH6 is perturbed and the expression of MKI67 is measured. Determine whether MKI67 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26876
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FNTA and monitor FIGNL1 expression. Decide whether this perturbation leads to a significant alteration in FIGNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FNTA and monitor FIGNL1 expression. Decide whether this perturbation leads to a significant alteration in FIGNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17048
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBAP1 and then measure expression of UBAP1. Does this perturbation cause a significant change in UBAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBAP1 and then measure expression of UBAP1. Does this perturbation cause a significant change in UBAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57124
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTK and examine the expression of CDKN1A. Does perturbing TTK lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTK and examine the expression of CDKN1A. Does perturbing TTK lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56331
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARL2 is perturbed and INPP4B expression is measured. Determine whether INPP4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARL2 is perturbed and INPP4B expression is measured. Determine whether INPP4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1949
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF3 is perturbed and the expression of STMN1 is measured. Determine whether STMN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF3 is perturbed and the expression of STMN1 is measured. Determine whether STMN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38746
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTF2 is perturbed and the expression of ZMAT3 is measured. Determine whether ZMAT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTF2 is perturbed and the expression of ZMAT3 is measured. Determine whether ZMAT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56236
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDHD1 is perturbed and the expression of CCDC152 is measured. Determine whether CCDC152 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDHD1 is perturbed and the expression of CCDC152 is measured. Determine whether CCDC152 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59506
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOL10 and examine the expression of SNRPA. Does perturbing NOL10 lead to a significant change in SNRPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOL10 and examine the expression of SNRPA. Does perturbing NOL10 lead to a significant change in SNRPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31831
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FAM50A is associated with a significant change in SLC7A6OS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FAM50A is associated with a significant change in SLC7A6OS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16435
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYS1 is perturbed and SYS1 expression is measured. Determine whether SYS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYS1 is perturbed and SYS1 expression is measured. Determine whether SYS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52389
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PARN is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PARN is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34193
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF292 is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF292 is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61576
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KAT8 is associated with a significant change in ESS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KAT8 is associated with a significant change in ESS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22715
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBQLN4 is perturbed and the expression of ALDH1A3 is measured. Determine whether ALDH1A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBQLN4 is perturbed and the expression of ALDH1A3 is measured. Determine whether ALDH1A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57466
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBE2Z, does the expression profile of SLC39A8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBE2Z, does the expression profile of SLC39A8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57387
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C3 is perturbed and CALR expression is observed. Does this perturbation lead to a significant difference in CALR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C3 is perturbed and CALR expression is observed. Does this perturbation lead to a significant difference in CALR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19193
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF407 is perturbed and the expression of CLCN7 is measured. Does this perturbation cause a significant change in CLCN7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF407 is perturbed and the expression of CLCN7 is measured. Does this perturbation cause a significant change in CLCN7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61610
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL26L1 is associated with a significant change in LXN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL26L1 is associated with a significant change in LXN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43825
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ALDOA is perturbed and the expression of SNHG1 is measured. Does this perturbation cause a significant change in SNHG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ALDOA is perturbed and the expression of SNHG1 is measured. Does this perturbation cause a significant change in SNHG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1090
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRNP40 is perturbed and the expression of CCT3 is measured. Does this perturbation cause a significant change in CCT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRNP40 is perturbed and the expression of CCT3 is measured. Does this perturbation cause a significant change in CCT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49880
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOD2 is perturbed and SOD2 expression is quantified. Does this perturbation result in a significant change in SOD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOD2 is perturbed and SOD2 expression is quantified. Does this perturbation result in a significant change in SOD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50402
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ITGB1BP1 is perturbed and ITGB1BP1 expression is quantified. Does this perturbation result in a significant change in ITGB1BP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ITGB1BP1 is perturbed and ITGB1BP1 expression is quantified. Does this perturbation result in a significant change in ITGB1BP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22412
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDK1 is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDK1 is perturbed and MKI67 expression is quantified. Does this perturbation result in a significant change in MKI67 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6442
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAF2 is perturbed and SPAG1 expression is quantified. Does this perturbation result in a significant change in SPAG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAF2 is perturbed and SPAG1 expression is quantified. Does this perturbation result in a significant change in SPAG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52732
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL36AL is perturbed and MGAT2 expression is observed. Does this perturbation lead to a significant difference in MGAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL36AL is perturbed and MGAT2 expression is observed. Does this perturbation lead to a significant difference in MGAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44243
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL17 is associated with a significant change in MT-ND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL17 is associated with a significant change in MT-ND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27135
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2E1 is associated with a significant change in SLC8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2E1 is associated with a significant change in SLC8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18845
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP54 and monitor SRP54 expression. Decide whether this perturbation leads to a significant alteration in SRP54 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP54 and monitor SRP54 expression. Decide whether this perturbation leads to a significant alteration in SRP54 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51128
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAM16 is associated with a significant change in PSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAM16 is associated with a significant change in PSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34145
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in PWWP3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in PWWP3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56285
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HMGB3 is perturbed and SRP14 expression is measured. Determine whether SRP14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HMGB3 is perturbed and SRP14 expression is measured. Determine whether SRP14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20229
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ACTR3 and monitor MYBL2 expression. Decide whether this perturbation leads to a significant alteration in MYBL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ACTR3 and monitor MYBL2 expression. Decide whether this perturbation leads to a significant alteration in MYBL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":698
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPS17 and monitor MT-CO1 expression. Decide whether this perturbation leads to a significant alteration in MT-CO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPS17 and monitor MT-CO1 expression. Decide whether this perturbation leads to a significant alteration in MT-CO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28278
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL2 is perturbed and MT-ND3 expression is measured. Determine whether MT-ND3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL2 is perturbed and MT-ND3 expression is measured. Determine whether MT-ND3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27239
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP2CA is perturbed and the expression of ACTA2 is measured. Does this perturbation cause a significant change in ACTA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP2CA is perturbed and the expression of ACTA2 is measured. Does this perturbation cause a significant change in ACTA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38000
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMB1, does the expression profile of KIFC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMB1, does the expression profile of KIFC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39287
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DYNLL2 and then measure expression of QDPR. Does this perturbation cause a significant change in QDPR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DYNLL2 and then measure expression of QDPR. Does this perturbation cause a significant change in QDPR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13474
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BRD2, does the expression profile of NPC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BRD2, does the expression profile of NPC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3887
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARF4 is perturbed and the expression of LPCAT1 is measured. Does this perturbation cause a significant change in LPCAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARF4 is perturbed and the expression of LPCAT1 is measured. Does this perturbation cause a significant change in LPCAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1780
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL15 is perturbed and DEPDC1 expression is observed. Does this perturbation lead to a significant difference in DEPDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL15 is perturbed and DEPDC1 expression is observed. Does this perturbation lead to a significant difference in DEPDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43523
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DCTN1 and monitor CPTP expression. Decide whether this perturbation leads to a significant alteration in CPTP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DCTN1 and monitor CPTP expression. Decide whether this perturbation leads to a significant alteration in CPTP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10828
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ACTR2 is perturbed and ACTR2 expression is observed. Does this perturbation lead to a significant difference in ACTR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ACTR2 is perturbed and ACTR2 expression is observed. Does this perturbation lead to a significant difference in ACTR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":663
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COX15 and monitor GPX4 expression. Decide whether this perturbation leads to a significant alteration in GPX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COX15 and monitor GPX4 expression. Decide whether this perturbation leads to a significant alteration in GPX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9258
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which METTL17 is perturbed and SSR3 expression is observed. Does this perturbation lead to a significant difference in SSR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which METTL17 is perturbed and SSR3 expression is observed. Does this perturbation lead to a significant difference in SSR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26103
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SFSWAP is associated with a significant change in FAM111B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SFSWAP is associated with a significant change in FAM111B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48155
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GET3 is perturbed and GET3 expression is measured. Determine whether GET3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GET3 is perturbed and GET3 expression is measured. Determine whether GET3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17649
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC16 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC16 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6005
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP153, does the expression profile of NUP153 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP153, does the expression profile of NUP153 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33077
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSME1 is perturbed and FXYD5 expression is quantified. Does this perturbation result in a significant change in FXYD5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSME1 is perturbed and FXYD5 expression is quantified. Does this perturbation result in a significant change in FXYD5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40032
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ORC1, does the expression profile of MCM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ORC1, does the expression profile of MCM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33667
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DTL, does the expression profile of OIP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DTL, does the expression profile of OIP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13297
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAD2L1 is perturbed and MAD2L1 expression is measured. Determine whether MAD2L1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAD2L1 is perturbed and MAD2L1 expression is measured. Determine whether MAD2L1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24529
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA3 is associated with a significant change in KRT81 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA3 is associated with a significant change in KRT81 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57055
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL8 is perturbed and the expression of TRIP13 is measured. Determine whether TRIP13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL8 is perturbed and the expression of TRIP13 is measured. Determine whether TRIP13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44576
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LAMTOR3 is perturbed and PRDX1 expression is observed. Does this perturbation lead to a significant difference in PRDX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LAMTOR3 is perturbed and PRDX1 expression is observed. Does this perturbation lead to a significant difference in PRDX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23623
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL15 and monitor MRPL15 expression. Decide whether this perturbation leads to a significant alteration in MRPL15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL15 and monitor MRPL15 expression. Decide whether this perturbation leads to a significant alteration in MRPL15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27068
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SDHC is associated with a significant change in TGM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SDHC is associated with a significant change in TGM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47245
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IPO13, does the expression profile of CENPW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IPO13, does the expression profile of CENPW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22167
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VPS28 is associated with a significant change in CXCL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VPS28 is associated with a significant change in CXCL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59055
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1A, does the expression profile of MSMO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1A, does the expression profile of MSMO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2857
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EXOSC8 is perturbed and the expression of KIF15 is measured. Does this perturbation cause a significant change in KIF15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EXOSC8 is perturbed and the expression of KIF15 is measured. Does this perturbation cause a significant change in KIF15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16170
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and TRIB3 expression is measured. Determine whether TRIB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and TRIB3 expression is measured. Determine whether TRIB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14179
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CYCS, does the expression profile of CYCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CYCS, does the expression profile of CYCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10507
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPD2 is perturbed and RSPH3 expression is measured. Determine whether RSPH3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPD2 is perturbed and RSPH3 expression is measured. Determine whether RSPH3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50129
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IFITM3 is perturbed and IFITM3 expression is measured. Determine whether IFITM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IFITM3 is perturbed and IFITM3 expression is measured. Determine whether IFITM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21249
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS23 is perturbed and MT-ND2 expression is measured. Determine whether MT-ND2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS23 is perturbed and MT-ND2 expression is measured. Determine whether MT-ND2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28499
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DCTN6 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DCTN6 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10963
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAT2A is associated with a significant change in MAT2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAT2A is associated with a significant change in MAT2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24755
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PNPT1 is perturbed and MT-ND6 expression is quantified. Does this perturbation result in a significant change in MT-ND6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PNPT1 is perturbed and MT-ND6 expression is quantified. Does this perturbation result in a significant change in MT-ND6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36092
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to METTL14 and then measure expression of XRCC5. Does this perturbation cause a significant change in XRCC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to METTL14 and then measure expression of XRCC5. Does this perturbation cause a significant change in XRCC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26054
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBAP1 is associated with a significant change in SFRP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBAP1 is associated with a significant change in SFRP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57145
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80C is perturbed and INO80C expression is quantified. Does this perturbation result in a significant change in INO80C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80C is perturbed and INO80C expression is quantified. Does this perturbation result in a significant change in INO80C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21602
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR3F is perturbed and ZNF410 expression is quantified. Does this perturbation result in a significant change in ZNF410 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR3F is perturbed and ZNF410 expression is quantified. Does this perturbation result in a significant change in ZNF410 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37122
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RAN and then measure expression of RAN. Does this perturbation cause a significant change in RAN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RAN and then measure expression of RAN. Does this perturbation cause a significant change in RAN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41224
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTCD3 is perturbed and the expression of SLF1 is measured. Determine whether SLF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTCD3 is perturbed and the expression of SLF1 is measured. Determine whether SLF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40276
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ILF2 is perturbed and the expression of IQCB1 is measured. Determine whether IQCB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ILF2 is perturbed and the expression of IQCB1 is measured. Determine whether IQCB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21356
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OXA1L is perturbed and the expression of OXA1L is measured. Determine whether OXA1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OXA1L is perturbed and the expression of OXA1L is measured. Determine whether OXA1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33906
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF207 is perturbed and the expression of ZNF207 is measured. Does this perturbation cause a significant change in ZNF207 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF207 is perturbed and the expression of ZNF207 is measured. Does this perturbation cause a significant change in ZNF207 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61470
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KDM6A and monitor KLF2 expression. Decide whether this perturbation leads to a significant alteration in KLF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KDM6A and monitor KLF2 expression. Decide whether this perturbation leads to a significant alteration in KLF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22948
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TFRC is perturbed and MAPK6 expression is measured. Determine whether MAPK6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TFRC is perturbed and MAPK6 expression is measured. Determine whether MAPK6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53719
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLCC1 is associated with a significant change in LINC01638 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLCC1 is associated with a significant change in LINC01638 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7875
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUBP1 is perturbed and the expression of KRT80 is measured. Determine whether KRT80 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUBP1 is perturbed and the expression of KRT80 is measured. Determine whether KRT80 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32756
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPTF and then measure expression of CENPV. Does this perturbation cause a significant change in CENPV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPTF and then measure expression of CENPV. Does this perturbation cause a significant change in CENPV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3804
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBM10 is perturbed and the expression of BUB1B is measured. Does this perturbation cause a significant change in BUB1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBM10 is perturbed and the expression of BUB1B is measured. Does this perturbation cause a significant change in BUB1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41510
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DSN1 and examine the expression of TRMT1L. Does perturbing DSN1 lead to a significant change in TRMT1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DSN1 and examine the expression of TRMT1L. Does perturbing DSN1 lead to a significant change in TRMT1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13231
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR3E is perturbed and HAUS8 expression is quantified. Does this perturbation result in a significant change in HAUS8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR3E is perturbed and HAUS8 expression is quantified. Does this perturbation result in a significant change in HAUS8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37092
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL13 and examine the expression of ARL14EP. Does perturbing MRPL13 lead to a significant change in ARL14EP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL13 and examine the expression of ARL14EP. Does perturbing MRPL13 lead to a significant change in ARL14EP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27011
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and DDIT4 expression is quantified. Does this perturbation result in a significant change in DDIT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and DDIT4 expression is quantified. Does this perturbation result in a significant change in DDIT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4952
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPA1, does the expression profile of TMSB15A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPA1, does the expression profile of TMSB15A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43017
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SERBP1 is perturbed and the expression of PHLDB2 is measured. Does this perturbation cause a significant change in PHLDB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SERBP1 is perturbed and the expression of PHLDB2 is measured. Does this perturbation cause a significant change in PHLDB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47620
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ESF1 is perturbed and the expression of MCM7 is measured. Does this perturbation cause a significant change in MCM7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ESF1 is perturbed and the expression of MCM7 is measured. Does this perturbation cause a significant change in MCM7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15620
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZDHHC7 is associated with a significant change in AXL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZDHHC7 is associated with a significant change in AXL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61245
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TPRKB is perturbed and TPRKB expression is observed. Does this perturbation lead to a significant difference in TPRKB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TPRKB is perturbed and TPRKB expression is observed. Does this perturbation lead to a significant difference in TPRKB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55363
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NOP2 and monitor PRC1 expression. Decide whether this perturbation leads to a significant alteration in PRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NOP2 and monitor PRC1 expression. Decide whether this perturbation leads to a significant alteration in PRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32198
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DNMT1 and monitor KRT81 expression. Decide whether this perturbation leads to a significant alteration in KRT81 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNMT1 and monitor KRT81 expression. Decide whether this perturbation leads to a significant alteration in KRT81 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12808
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOC3 and then measure expression of NUDT12. Does this perturbation cause a significant change in NUDT12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOC3 and then measure expression of NUDT12. Does this perturbation cause a significant change in NUDT12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15814
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DPH3, does the expression profile of C8orf58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DPH3, does the expression profile of C8orf58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13007
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPS3 and examine the expression of TTK. Does perturbing COPS3 lead to a significant change in TTK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPS3 and examine the expression of TTK. Does perturbing COPS3 lead to a significant change in TTK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8881
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX17 is associated with a significant change in SFRP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX17 is associated with a significant change in SFRP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11175
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SON and monitor FIBP expression. Decide whether this perturbation leads to a significant alteration in FIBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SON and monitor FIBP expression. Decide whether this perturbation leads to a significant alteration in FIBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50458
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USP5, does the expression profile of USP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USP5, does the expression profile of USP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58327
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RBM8A is perturbed and BRCA1 expression is measured. Determine whether BRCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RBM8A is perturbed and BRCA1 expression is measured. Determine whether BRCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41839
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBA2 is perturbed and SERPINB2 expression is observed. Does this perturbation lead to a significant difference in SERPINB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBA2 is perturbed and SERPINB2 expression is observed. Does this perturbation lead to a significant difference in SERPINB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57023
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UQCRC1 is perturbed and PLS3 expression is observed. Does this perturbation lead to a significant difference in PLS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UQCRC1 is perturbed and PLS3 expression is observed. Does this perturbation lead to a significant difference in PLS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57913
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, F8A1 is perturbed and the expression of CHKB is measured. Does this perturbation cause a significant change in CHKB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, F8A1 is perturbed and the expression of CHKB is measured. Does this perturbation cause a significant change in CHKB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16230
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL28 is associated with a significant change in RPL28 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL28 is associated with a significant change in RPL28 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43905
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GABPB1 and monitor SUPT16H expression. Decide whether this perturbation leads to a significant alteration in SUPT16H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GABPB1 and monitor SUPT16H expression. Decide whether this perturbation leads to a significant alteration in SUPT16H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17248
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MYSM1 is perturbed and the expression of TMEM120B is measured. Does this perturbation cause a significant change in TMEM120B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MYSM1 is perturbed and the expression of TMEM120B is measured. Does this perturbation cause a significant change in TMEM120B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29390
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EMC7 is perturbed and EMC7 expression is measured. Determine whether EMC7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EMC7 is perturbed and EMC7 expression is measured. Determine whether EMC7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15309
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRMT10C is perturbed and the expression of MT-CYB is measured. Determine whether MT-CYB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRMT10C is perturbed and the expression of MT-CYB is measured. Determine whether MT-CYB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55686
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COG2 is perturbed and PLCD3 expression is quantified. Does this perturbation result in a significant change in PLCD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COG2 is perturbed and PLCD3 expression is quantified. Does this perturbation result in a significant change in PLCD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8542
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMC3, does the expression profile of CEP128 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMC3, does the expression profile of CEP128 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39567
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBE2H is perturbed and PLAU expression is observed. Does this perturbation lead to a significant difference in PLAU expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBE2H is perturbed and PLAU expression is observed. Does this perturbation lead to a significant difference in PLAU expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57233
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L1 is perturbed and BCL2L1 expression is quantified. Does this perturbation result in a significant change in BCL2L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L1 is perturbed and BCL2L1 expression is quantified. Does this perturbation result in a significant change in BCL2L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3422
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SBNO1, does the expression profile of ANAPC15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SBNO1, does the expression profile of ANAPC15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46917
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTB is perturbed and the expression of ACTB is measured. Determine whether ACTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTB is perturbed and the expression of ACTB is measured. Determine whether ACTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":516
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4A3 and then measure expression of CIT. Does this perturbation cause a significant change in CIT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4A3 and then measure expression of CIT. Does this perturbation cause a significant change in CIT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14644
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMA16 and then measure expression of TMA16. Does this perturbation cause a significant change in TMA16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMA16 and then measure expression of TMA16. Does this perturbation cause a significant change in TMA16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54514
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDIPT is perturbed and CDIPT expression is quantified. Does this perturbation result in a significant change in CDIPT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDIPT is perturbed and CDIPT expression is quantified. Does this perturbation result in a significant change in CDIPT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6402
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YRDC, does the expression profile of C1orf122 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YRDC, does the expression profile of C1orf122 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60897
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPP38 and then measure expression of SMC6. Does this perturbation cause a significant change in SMC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPP38 and then measure expression of SMC6. Does this perturbation cause a significant change in SMC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44874
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED19 and examine the expression of TMX2. Does perturbing MED19 lead to a significant change in TMX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED19 and examine the expression of TMX2. Does perturbing MED19 lead to a significant change in TMX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25541
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC6 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC6 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6310
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEF2A is perturbed and CPSF7 expression is quantified. Does this perturbation result in a significant change in CPSF7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEF2A is perturbed and CPSF7 expression is quantified. Does this perturbation result in a significant change in CPSF7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25862
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLC2 is perturbed and the expression of KLC2 is measured. Determine whether KLC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLC2 is perturbed and the expression of KLC2 is measured. Determine whether KLC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23226
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COX5B is perturbed and LMAN2L expression is observed. Does this perturbation lead to a significant difference in LMAN2L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COX5B is perturbed and LMAN2L expression is observed. Does this perturbation lead to a significant difference in LMAN2L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9353
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL18, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL18, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43577
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL37 and examine the expression of POLA1. Does perturbing RPL37 lead to a significant change in POLA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL37 and examine the expression of POLA1. Does perturbing RPL37 lead to a significant change in POLA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44251
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TFIP11 is associated with a significant change in KNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TFIP11 is associated with a significant change in KNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53695
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM4, does the expression profile of MT-ND3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM4, does the expression profile of MT-ND3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38287
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of MYBL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of MYBL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14227
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NLE1 is perturbed and the expression of KIF4A is measured. Determine whether KIF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NLE1 is perturbed and the expression of KIF4A is measured. Determine whether KIF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31626
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGPP1 is associated with a significant change in SGPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGPP1 is associated with a significant change in SGPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48195
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GTF2H4 is perturbed and PLK4 expression is observed. Does this perturbation lead to a significant difference in PLK4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GTF2H4 is perturbed and PLK4 expression is observed. Does this perturbation lead to a significant difference in PLK4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19073
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAG6 and then measure expression of ACTN1. Does this perturbation cause a significant change in ACTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAG6 and then measure expression of ACTN1. Does this perturbation cause a significant change in ACTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3224
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC8 is perturbed and AGPS expression is quantified. Does this perturbation result in a significant change in AGPS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC8 is perturbed and AGPS expression is quantified. Does this perturbation result in a significant change in AGPS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12642
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABCB10 and examine the expression of FKBP5. Does perturbing ABCB10 lead to a significant change in FKBP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABCB10 and examine the expression of FKBP5. Does perturbing ABCB10 lead to a significant change in FKBP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":221
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED29 is associated with a significant change in SPC25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED29 is associated with a significant change in SPC25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25685
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MICOS10 and then measure expression of MICOS10. Does this perturbation cause a significant change in MICOS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MICOS10 and then measure expression of MICOS10. Does this perturbation cause a significant change in MICOS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26284
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CASC3 is perturbed and TAF1D expression is quantified. Does this perturbation result in a significant change in TAF1D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CASC3 is perturbed and TAF1D expression is quantified. Does this perturbation result in a significant change in TAF1D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4992
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR3C and then measure expression of POLE2. Does this perturbation cause a significant change in POLE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR3C and then measure expression of POLE2. Does this perturbation cause a significant change in POLE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37044
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDT1 is perturbed and RRM2 expression is observed. Does this perturbation lead to a significant difference in RRM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDT1 is perturbed and RRM2 expression is observed. Does this perturbation lead to a significant difference in RRM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6623
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RIOK1, does the expression profile of NDRG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RIOK1, does the expression profile of NDRG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42467
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PHB is perturbed and BOLA3 expression is observed. Does this perturbation lead to a significant difference in BOLA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PHB is perturbed and BOLA3 expression is observed. Does this perturbation lead to a significant difference in BOLA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35363
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LARS is associated with a significant change in DDIT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LARS is associated with a significant change in DDIT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23695
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CD2BP2 is perturbed and TRIOBP expression is quantified. Does this perturbation result in a significant change in TRIOBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CD2BP2 is perturbed and TRIOBP expression is quantified. Does this perturbation result in a significant change in TRIOBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5922
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL11 and then measure expression of MT-ND3. Does this perturbation cause a significant change in MT-ND3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL11 and then measure expression of MT-ND3. Does this perturbation cause a significant change in MT-ND3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26994
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BET1 and examine the expression of CXCL8. Does perturbing BET1 lead to a significant change in CXCL8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BET1 and examine the expression of CXCL8. Does perturbing BET1 lead to a significant change in CXCL8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3571
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAU2, does the expression profile of MCM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAU2, does the expression profile of MCM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24787
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NPEPPS is perturbed and CDK5 expression is observed. Does this perturbation lead to a significant difference in CDK5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NPEPPS is perturbed and CDK5 expression is observed. Does this perturbation lead to a significant difference in CDK5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32293
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS33A is perturbed and ZBED3 expression is measured. Determine whether ZBED3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS33A is perturbed and ZBED3 expression is measured. Determine whether ZBED3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59109
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of PSAT1. Does this perturbation cause a significant change in PSAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of PSAT1. Does this perturbation cause a significant change in PSAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52974
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KAT8 and monitor POT1 expression. Decide whether this perturbation leads to a significant alteration in POT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KAT8 and monitor POT1 expression. Decide whether this perturbation leads to a significant alteration in POT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22728
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of CCN3 is measured. Determine whether CCN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of CCN3 is measured. Determine whether CCN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39886
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFS5 is associated with a significant change in TBL1X expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFS5 is associated with a significant change in TBL1X expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30945
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD7 is perturbed and TRIM7 expression is measured. Determine whether TRIM7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD7 is perturbed and TRIM7 expression is measured. Determine whether TRIM7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39959
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCNQ is perturbed and CCNT1 expression is measured. Determine whether CCNT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCNQ is perturbed and CCNT1 expression is measured. Determine whether CCNT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5659
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CENPI is perturbed and CDCA7 expression is measured. Determine whether CDCA7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CENPI is perturbed and CDCA7 expression is measured. Determine whether CDCA7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6829
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL43 and monitor MT-ND6 expression. Decide whether this perturbation leads to a significant alteration in MT-ND6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL43 and monitor MT-ND6 expression. Decide whether this perturbation leads to a significant alteration in MT-ND6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27828
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ANKRD17 is perturbed and the expression of RASSF1 is measured. Does this perturbation cause a significant change in RASSF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ANKRD17 is perturbed and the expression of RASSF1 is measured. Does this perturbation cause a significant change in RASSF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1530
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL16 and then measure expression of MT-ND3. Does this perturbation cause a significant change in MT-ND3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL16 and then measure expression of MT-ND3. Does this perturbation cause a significant change in MT-ND3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27114
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ILF3 and examine the expression of XRCC2. Does perturbing ILF3 lead to a significant change in XRCC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ILF3 and examine the expression of XRCC2. Does perturbing ILF3 lead to a significant change in XRCC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21371
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UROD, does the expression profile of THY1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UROD, does the expression profile of THY1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58167
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPAT, does the expression profile of UBE2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPAT, does the expression profile of UBE2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18257
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb VPS33A and examine the expression of VPS33A. Does perturbing VPS33A lead to a significant change in VPS33A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb VPS33A and examine the expression of VPS33A. Does perturbing VPS33A lead to a significant change in VPS33A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59121
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C9orf78 and monitor RABL6 expression. Decide whether this perturbation leads to a significant alteration in RABL6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C9orf78 and monitor RABL6 expression. Decide whether this perturbation leads to a significant alteration in RABL6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4738
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NCKAP1 and monitor IDS expression. Decide whether this perturbation leads to a significant alteration in IDS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NCKAP1 and monitor IDS expression. Decide whether this perturbation leads to a significant alteration in IDS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30288
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SBNO1 is perturbed and ANAPC15 expression is quantified. Does this perturbation result in a significant change in ANAPC15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SBNO1 is perturbed and ANAPC15 expression is quantified. Does this perturbation result in a significant change in ANAPC15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46912
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TNRC6A is associated with a significant change in ESD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TNRC6A is associated with a significant change in ESD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54875
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX15 is perturbed and the expression of PSIP1 is measured. Does this perturbation cause a significant change in PSIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX15 is perturbed and the expression of PSIP1 is measured. Does this perturbation cause a significant change in PSIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12040
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF2B is perturbed and RBM14 expression is quantified. Does this perturbation result in a significant change in RBM14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF2B is perturbed and RBM14 expression is quantified. Does this perturbation result in a significant change in RBM14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18832
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRCAP is perturbed and the expression of RNASEK is measured. Does this perturbation cause a significant change in RNASEK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRCAP is perturbed and the expression of RNASEK is measured. Does this perturbation cause a significant change in RNASEK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50990
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBLL1 is perturbed and FST expression is quantified. Does this perturbation result in a significant change in FST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBLL1 is perturbed and FST expression is quantified. Does this perturbation result in a significant change in FST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5082
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL35 is perturbed and the expression of KIF2C is measured. Determine whether KIF2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL35 is perturbed and the expression of KIF2C is measured. Determine whether KIF2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44126
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PAXBP1 is perturbed and the expression of TMPO-AS1 is measured. Does this perturbation cause a significant change in TMPO-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PAXBP1 is perturbed and the expression of TMPO-AS1 is measured. Does this perturbation cause a significant change in TMPO-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34210
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AKIRIN2 and examine the expression of SKP2. Does perturbing AKIRIN2 lead to a significant change in SKP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AKIRIN2 and examine the expression of SKP2. Does perturbing AKIRIN2 lead to a significant change in SKP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1061
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCR is perturbed and WDR60 expression is quantified. Does this perturbation result in a significant change in WDR60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCR is perturbed and WDR60 expression is quantified. Does this perturbation result in a significant change in WDR60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3502
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BOD1L1, does the expression profile of BOD1L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BOD1L1, does the expression profile of BOD1L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3727
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIN is perturbed and the expression of CCDC28B is measured. Determine whether CCDC28B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIN is perturbed and the expression of CCDC28B is measured. Determine whether CCDC28B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23216
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS19 and examine the expression of CDKN1A. Does perturbing RPS19 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS19 and examine the expression of CDKN1A. Does perturbing RPS19 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45231
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL3 is perturbed and BUB1 expression is observed. Does this perturbation lead to a significant difference in BUB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL3 is perturbed and BUB1 expression is observed. Does this perturbation lead to a significant difference in BUB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43953
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPP1CA, does the expression profile of NHP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPP1CA, does the expression profile of NHP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37707
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRMT5 and examine the expression of FOXC2. Does perturbing PRMT5 lead to a significant change in FOXC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRMT5 and examine the expression of FOXC2. Does perturbing PRMT5 lead to a significant change in FOXC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38631
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YBX1 is perturbed and XXYLT1 expression is measured. Determine whether XXYLT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YBX1 is perturbed and XXYLT1 expression is measured. Determine whether XXYLT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60699
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCDC137 and then measure expression of ASMTL. Does this perturbation cause a significant change in ASMTL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCDC137 and then measure expression of ASMTL. Does this perturbation cause a significant change in ASMTL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5234
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FUNDC2 and monitor SSR2 expression. Decide whether this perturbation leads to a significant alteration in SSR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FUNDC2 and monitor SSR2 expression. Decide whether this perturbation leads to a significant alteration in SSR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17128
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL4 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL4 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44383
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAU2 is perturbed and the expression of LPAR1 is measured. Determine whether LPAR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAU2 is perturbed and the expression of LPAR1 is measured. Determine whether LPAR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24796
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TAF1B and then measure expression of USP1. Does this perturbation cause a significant change in USP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TAF1B and then measure expression of USP1. Does this perturbation cause a significant change in USP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52654
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SURF6 is perturbed and CEP152 expression is observed. Does this perturbation lead to a significant difference in CEP152 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SURF6 is perturbed and CEP152 expression is observed. Does this perturbation lead to a significant difference in CEP152 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52293
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF7 is perturbed and the expression of EEF1AKMT4 is measured. Does this perturbation cause a significant change in EEF1AKMT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF7 is perturbed and the expression of EEF1AKMT4 is measured. Does this perturbation cause a significant change in EEF1AKMT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52850
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZCCHC9 and examine the expression of HMMR. Does perturbing ZCCHC9 lead to a significant change in HMMR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZCCHC9 and examine the expression of HMMR. Does perturbing ZCCHC9 lead to a significant change in HMMR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61191
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBCC is perturbed and the expression of C21orf58 is measured. Does this perturbation cause a significant change in C21orf58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBCC is perturbed and the expression of C21orf58 is measured. Does this perturbation cause a significant change in C21orf58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53130
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBCB is perturbed and the expression of SPC25 is measured. Determine whether SPC25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBCB is perturbed and the expression of SPC25 is measured. Determine whether SPC25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53106
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELP2 and then measure expression of NUPR1. Does this perturbation cause a significant change in NUPR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELP2 and then measure expression of NUPR1. Does this perturbation cause a significant change in NUPR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15074
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISY1 is associated with a significant change in MOXD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISY1 is associated with a significant change in MOXD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22405
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRMT1 is associated with a significant change in PRMT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRMT1 is associated with a significant change in PRMT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38595
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SSRP1 is perturbed and SAMD1 expression is quantified. Does this perturbation result in a significant change in SAMD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SSRP1 is perturbed and SAMD1 expression is quantified. Does this perturbation result in a significant change in SAMD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51672
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNOT1 and then measure expression of ANGPTL4. Does this perturbation cause a significant change in ANGPTL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNOT1 and then measure expression of ANGPTL4. Does this perturbation cause a significant change in ANGPTL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8264
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGS1, does the expression profile of MT-ND3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGS1, does the expression profile of MT-ND3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35307
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX41 is perturbed and the expression of CA9 is measured. Determine whether CA9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX41 is perturbed and the expression of CA9 is measured. Determine whether CA9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11476
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALDOA, does the expression profile of AL161431.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALDOA, does the expression profile of AL161431.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1087
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS29 is associated with a significant change in LRR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS29 is associated with a significant change in LRR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45575
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL18 is associated with a significant change in MT-ND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL18 is associated with a significant change in MT-ND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27165
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MOB4 and monitor MCM7 expression. Decide whether this perturbation leads to a significant alteration in MCM7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MOB4 and monitor MCM7 expression. Decide whether this perturbation leads to a significant alteration in MCM7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26728
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRORP and then measure expression of MT-CO2. Does this perturbation cause a significant change in MT-CO2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRORP and then measure expression of MT-CO2. Does this perturbation cause a significant change in MT-CO2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38644
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR33 is perturbed and PARPBP expression is quantified. Does this perturbation result in a significant change in PARPBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR33 is perturbed and PARPBP expression is quantified. Does this perturbation result in a significant change in PARPBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59712
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DONSON, does the expression profile of GINS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DONSON, does the expression profile of GINS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12927
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LTBP4, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LTBP4, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24407
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMC5 is associated with a significant change in CDCA7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMC5 is associated with a significant change in CDCA7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49215
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLR3K is perturbed and GTF2H2 expression is observed. Does this perturbation lead to a significant difference in GTF2H2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLR3K is perturbed and GTF2H2 expression is observed. Does this perturbation lead to a significant difference in GTF2H2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37183
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS24, does the expression profile of PRIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS24, does the expression profile of PRIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45407
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TEAD3 is perturbed and the expression of MSANTD4 is measured. Does this perturbation cause a significant change in MSANTD4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TEAD3 is perturbed and the expression of MSANTD4 is measured. Does this perturbation cause a significant change in MSANTD4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53340
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SUPT20H is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SUPT20H is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52143
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS25 is perturbed and GNAI1 expression is quantified. Does this perturbation result in a significant change in GNAI1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS25 is perturbed and GNAI1 expression is quantified. Does this perturbation result in a significant change in GNAI1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45432
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLRX5 is perturbed and MT-CO1 expression is quantified. Does this perturbation result in a significant change in MT-CO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLRX5 is perturbed and MT-CO1 expression is quantified. Does this perturbation result in a significant change in MT-CO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18082
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MPHOSPH10 is associated with a significant change in FEN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MPHOSPH10 is associated with a significant change in FEN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26835
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB4 and then measure expression of C6orf136. Does this perturbation cause a significant change in C6orf136 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB4 and then measure expression of C6orf136. Does this perturbation cause a significant change in C6orf136 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61034
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OPA1 is perturbed and MT-ND6 expression is measured. Determine whether MT-ND6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OPA1 is perturbed and MT-ND6 expression is measured. Determine whether MT-ND6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33659
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MYBL2 and then measure expression of MYBL2. Does this perturbation cause a significant change in MYBL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MYBL2 and then measure expression of MYBL2. Does this perturbation cause a significant change in MYBL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29284
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BIRC5 is perturbed and AURKA expression is quantified. Does this perturbation result in a significant change in AURKA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BIRC5 is perturbed and AURKA expression is quantified. Does this perturbation result in a significant change in AURKA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3602
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CASP8AP2 and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CASP8AP2 and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5014
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPY19L4 is perturbed and DBNDD2 expression is quantified. Does this perturbation result in a significant change in DBNDD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPY19L4 is perturbed and DBNDD2 expression is quantified. Does this perturbation result in a significant change in DBNDD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13102
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MCM4 and monitor MED23 expression. Decide whether this perturbation leads to a significant alteration in MED23 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MCM4 and monitor MED23 expression. Decide whether this perturbation leads to a significant alteration in MED23 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25198
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNLL2, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNLL2, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13487
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H13 and examine the expression of MIR100HG. Does perturbing ZC3H13 lead to a significant change in MIR100HG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H13 and examine the expression of MIR100HG. Does perturbing ZC3H13 lead to a significant change in MIR100HG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61091
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX42 is perturbed and XPO6 expression is quantified. Does this perturbation result in a significant change in XPO6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX42 is perturbed and XPO6 expression is quantified. Does this perturbation result in a significant change in XPO6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11512
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRCC6 and examine the expression of DDIT3. Does perturbing XRCC6 lead to a significant change in DDIT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRCC6 and examine the expression of DDIT3. Does perturbing XRCC6 lead to a significant change in DDIT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60521
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ENO1 is associated with a significant change in LINC01638 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ENO1 is associated with a significant change in LINC01638 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15355
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX55 and examine the expression of CDKN1A. Does perturbing DDX55 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX55 and examine the expression of CDKN1A. Does perturbing DDX55 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11671
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS23 is perturbed and MT-ND2 expression is quantified. Does this perturbation result in a significant change in MT-ND2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS23 is perturbed and MT-ND2 expression is quantified. Does this perturbation result in a significant change in MT-ND2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28492
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR1C is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR1C is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36522
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL23 is perturbed and MT-ND2 expression is measured. Determine whether MT-ND2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL23 is perturbed and MT-ND2 expression is measured. Determine whether MT-ND2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27359
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDC80, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDC80, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30407
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SSU72 is perturbed and the expression of OSTC is measured. Determine whether OSTC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SSU72 is perturbed and the expression of OSTC is measured. Determine whether OSTC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51716
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGS1 and examine the expression of HIST1H1D. Does perturbing TGS1 lead to a significant change in HIST1H1D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGS1 and examine the expression of HIST1H1D. Does perturbing TGS1 lead to a significant change in HIST1H1D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53731
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GEMIN6 is associated with a significant change in DYSF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GEMIN6 is associated with a significant change in DYSF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17525
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCDC115 is perturbed and CCNE2 expression is observed. Does this perturbation lead to a significant difference in CCNE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCDC115 is perturbed and CCNE2 expression is observed. Does this perturbation lead to a significant difference in CCNE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5163
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GTF2H4 is perturbed and the expression of SNHG4 is measured. Does this perturbation cause a significant change in SNHG4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GTF2H4 is perturbed and the expression of SNHG4 is measured. Does this perturbation cause a significant change in SNHG4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19050
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM4 is perturbed and the expression of MT-ND3 is measured. Determine whether MT-ND3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM4 is perturbed and the expression of MT-ND3 is measured. Determine whether MT-ND3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38286
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC4 and examine the expression of MAP1A. Does perturbing PSMC4 lead to a significant change in MAP1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC4 and examine the expression of MAP1A. Does perturbing PSMC4 lead to a significant change in MAP1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39591
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRPD2 and then measure expression of RSPH3. Does this perturbation cause a significant change in RSPH3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRPD2 and then measure expression of RSPH3. Does this perturbation cause a significant change in RSPH3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50124
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF1AD is perturbed and the expression of BCL2L12 is measured. Determine whether BCL2L12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF1AD is perturbed and the expression of BCL2L12 is measured. Determine whether BCL2L12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14016
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LIN54 and then measure expression of CHD3. Does this perturbation cause a significant change in CHD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LIN54 and then measure expression of CHD3. Does this perturbation cause a significant change in CHD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23934
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb WDR4 and monitor WDR4 expression. Decide whether this perturbation leads to a significant alteration in WDR4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb WDR4 and monitor WDR4 expression. Decide whether this perturbation leads to a significant alteration in WDR4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59778
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RBBP6 is perturbed and FLOT2 expression is measured. Determine whether FLOT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RBBP6 is perturbed and FLOT2 expression is measured. Determine whether FLOT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41449
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC7 and examine the expression of ZMAT3. Does perturbing THOC7 lead to a significant change in ZMAT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC7 and examine the expression of ZMAT3. Does perturbing THOC7 lead to a significant change in ZMAT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54011
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CPSF3 is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CPSF3 is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9623
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL28 is perturbed and the expression of MRPL28 is measured. Does this perturbation cause a significant change in MRPL28 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL28 is perturbed and the expression of MRPL28 is measured. Does this perturbation cause a significant change in MRPL28 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27420
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBTF, does the expression profile of ETFRF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBTF, does the expression profile of ETFRF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57557
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ILF3 and examine the expression of DARS2. Does perturbing ILF3 lead to a significant change in DARS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ILF3 and examine the expression of DARS2. Does perturbing ILF3 lead to a significant change in DARS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21381
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PALB2 is perturbed and POLQ expression is observed. Does this perturbation lead to a significant difference in POLQ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PALB2 is perturbed and POLQ expression is observed. Does this perturbation lead to a significant difference in POLQ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34123
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL37 and examine the expression of BLM. Does perturbing RPL37 lead to a significant change in BLM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL37 and examine the expression of BLM. Does perturbing RPL37 lead to a significant change in BLM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44271
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EEF2 and then measure expression of EEF2. Does this perturbation cause a significant change in EEF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EEF2 and then measure expression of EEF2. Does this perturbation cause a significant change in EEF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13804
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AATF is associated with a significant change in PIMREG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AATF is associated with a significant change in PIMREG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":205
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL18 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL18 is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43575
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COG2, does the expression profile of ARPIN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COG2, does the expression profile of ARPIN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8537
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL37A and then measure expression of RPL37A. Does this perturbation cause a significant change in RPL37A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL37A and then measure expression of RPL37A. Does this perturbation cause a significant change in RPL37A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44304
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM3AP, does the expression profile of CENPW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM3AP, does the expression profile of CENPW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25147
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM17 and examine the expression of FBXO32. Does perturbing RBM17 lead to a significant change in FBXO32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM17 and examine the expression of FBXO32. Does perturbing RBM17 lead to a significant change in FBXO32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41561
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRSF6 is perturbed and SRSF6 expression is observed. Does this perturbation lead to a significant difference in SRSF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRSF6 is perturbed and SRSF6 expression is observed. Does this perturbation lead to a significant difference in SRSF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51513
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COMTD1 is perturbed and the expression of HNRNPA1 is measured. Does this perturbation cause a significant change in HNRNPA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COMTD1 is perturbed and the expression of HNRNPA1 is measured. Does this perturbation cause a significant change in HNRNPA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8670
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EMC3 is associated with a significant change in MME expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EMC3 is associated with a significant change in MME expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15245
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS17 is perturbed and the expression of SPAG5 is measured. Determine whether SPAG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS17 is perturbed and the expression of SPAG5 is measured. Determine whether SPAG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45156
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCNH is perturbed and NCAPH expression is quantified. Does this perturbation result in a significant change in NCAPH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCNH is perturbed and NCAPH expression is quantified. Does this perturbation result in a significant change in NCAPH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5552
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLE1 is perturbed and STMN1 expression is quantified. Does this perturbation result in a significant change in STMN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLE1 is perturbed and STMN1 expression is quantified. Does this perturbation result in a significant change in STMN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17952
  }
]