,question,answer,question_new
627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of SAMM50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of SAMM50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4963,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and EIF4B expression is observed. Does this perturbation lead to a significant difference in EIF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and EIF4B expression is observed. Does this perturbation lead to a significant difference in EIF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ANKRD33. Does perturbing COPB1 lead to a significant change in ANKRD33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ANKRD33. Does perturbing COPB1 lead to a significant change in ANKRD33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZFHX3. Does perturbing SOCS1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZFHX3. Does perturbing SOCS1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4728,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor RP11-322J23.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-322J23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor RP11-322J23.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-322J23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1763,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and C12orf23 expression is observed. Does this perturbation lead to a significant difference in C12orf23 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and C12orf23 expression is observed. Does this perturbation lead to a significant difference in C12orf23 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
10,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of YTHDF2. Does perturbing TMED2 lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of YTHDF2. Does perturbing TMED2 lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3280,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Does this perturbation cause a significant change in AC018878.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Does this perturbation cause a significant change in AC018878.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4853,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and STK17B expression is observed. Does this perturbation lead to a significant difference in STK17B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and STK17B expression is observed. Does this perturbation lead to a significant difference in STK17B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and FGF11 expression is measured. Determine whether FGF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and FGF11 expression is measured. Determine whether FGF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AC007038.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AC007038.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of LDLR. Does perturbing IER3IP1 lead to a significant change in LDLR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of LDLR. Does perturbing IER3IP1 lead to a significant change in LDLR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and OBSCN expression is quantified. Does this perturbation result in a significant change in OBSCN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and OBSCN expression is quantified. Does this perturbation result in a significant change in OBSCN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and TROAP expression is measured. Determine whether TROAP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and TROAP expression is measured. Determine whether TROAP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in RP11-573D15.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in RP11-573D15.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ROCK1. Does this perturbation cause a significant change in ROCK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ROCK1. Does this perturbation cause a significant change in ROCK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4668,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor LINC01137 expression. Decide whether this perturbation leads to a significant alteration in LINC01137 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor LINC01137 expression. Decide whether this perturbation leads to a significant alteration in LINC01137 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Determine whether LIMS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Determine whether LIMS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
44,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of LPAR5. Does this perturbation cause a significant change in LPAR5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of LPAR5. Does this perturbation cause a significant change in LPAR5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in SBF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in SBF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Determine whether H1FX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Determine whether H1FX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of NAV1. Does this perturbation cause a significant change in NAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of NAV1. Does this perturbation cause a significant change in NAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SETD5-AS1 expression is measured. Determine whether SETD5-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SETD5-AS1 expression is measured. Determine whether SETD5-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in TOB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in TOB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and PRRC2B expression is measured. Determine whether PRRC2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and PRRC2B expression is measured. Determine whether PRRC2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3860,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of OR2T6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of OR2T6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and PGM3 expression is measured. Determine whether PGM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and PGM3 expression is measured. Determine whether PGM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CTBS expression is quantified. Does this perturbation result in a significant change in CTBS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CTBS expression is quantified. Does this perturbation result in a significant change in CTBS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2833,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and EXO1 expression is observed. Does this perturbation lead to a significant difference in EXO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and EXO1 expression is observed. Does this perturbation lead to a significant difference in EXO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and TOB2 expression is measured. Determine whether TOB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and TOB2 expression is measured. Determine whether TOB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IL18R1. Does perturbing CHERP lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IL18R1. Does perturbing CHERP lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1620,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Does this perturbation cause a significant change in ATP6AP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Does this perturbation cause a significant change in ATP6AP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1768,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor C12orf23 expression. Decide whether this perturbation leads to a significant alteration in C12orf23 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor C12orf23 expression. Decide whether this perturbation leads to a significant alteration in C12orf23 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
808,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor COPB1 expression. Decide whether this perturbation leads to a significant alteration in COPB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor COPB1 expression. Decide whether this perturbation leads to a significant alteration in COPB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
973,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is quantified. Does this perturbation result in a significant change in RP11-254F7.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is quantified. Does this perturbation result in a significant change in RP11-254F7.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4263,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RASGRP2 expression is observed. Does this perturbation lead to a significant difference in RASGRP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RASGRP2 expression is observed. Does this perturbation lead to a significant difference in RASGRP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and NTRK1 expression is measured. Determine whether NTRK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and NTRK1 expression is measured. Determine whether NTRK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CLINT1. Does this perturbation cause a significant change in CLINT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CLINT1. Does this perturbation cause a significant change in CLINT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
680,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Does this perturbation cause a significant change in ARSA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Does this perturbation cause a significant change in ARSA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2128,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ARSA. Does perturbing SLMO2 lead to a significant change in ARSA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ARSA. Does perturbing SLMO2 lead to a significant change in ARSA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZMYND8. Does this perturbation cause a significant change in ZMYND8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZMYND8. Does this perturbation cause a significant change in ZMYND8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1093,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-328J2.1 expression is observed. Does this perturbation lead to a significant difference in RP11-328J2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-328J2.1 expression is observed. Does this perturbation lead to a significant difference in RP11-328J2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2370,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Does this perturbation cause a significant change in PPP4R2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Does this perturbation cause a significant change in PPP4R2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and OBSCN expression is measured. Determine whether OBSCN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and OBSCN expression is measured. Determine whether OBSCN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Determine whether MS4A6E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Determine whether MS4A6E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of SLC25A35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of SLC25A35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of RP11-90P5.2. Does this perturbation cause a significant change in RP11-90P5.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of RP11-90P5.2. Does this perturbation cause a significant change in RP11-90P5.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Determine whether SLBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Determine whether SLBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4393,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ATAD2B expression is observed. Does this perturbation lead to a significant difference in ATAD2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ATAD2B expression is observed. Does this perturbation lead to a significant difference in ATAD2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Determine whether HLTF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Determine whether HLTF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of RP11-254F7.4. Does perturbing HSPA9 lead to a significant change in RP11-254F7.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of RP11-254F7.4. Does perturbing HSPA9 lead to a significant change in RP11-254F7.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2793,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Determine whether C17orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Determine whether C17orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and DNMBP expression is quantified. Does this perturbation result in a significant change in DNMBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and DNMBP expression is quantified. Does this perturbation result in a significant change in DNMBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of RP11-242O24.5. Does perturbing TMED10 lead to a significant change in RP11-242O24.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of RP11-242O24.5. Does perturbing TMED10 lead to a significant change in RP11-242O24.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3858,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor PHF21A expression. Decide whether this perturbation leads to a significant alteration in PHF21A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor PHF21A expression. Decide whether this perturbation leads to a significant alteration in PHF21A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3533,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and FCGRT expression is observed. Does this perturbation lead to a significant difference in FCGRT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and FCGRT expression is observed. Does this perturbation lead to a significant difference in FCGRT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of GPR146. Does this perturbation cause a significant change in GPR146 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of GPR146. Does this perturbation cause a significant change in GPR146 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in C6orf120 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in C6orf120 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and GALNT7 expression is measured. Determine whether GALNT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and GALNT7 expression is measured. Determine whether GALNT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2360,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Does this perturbation cause a significant change in FYTTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Does this perturbation cause a significant change in FYTTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SLC37A1. Does perturbing UFL1 lead to a significant change in SLC37A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SLC37A1. Does perturbing UFL1 lead to a significant change in SLC37A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of RP11-390B4.5. Does perturbing XRN1 lead to a significant change in RP11-390B4.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of RP11-390B4.5. Does perturbing XRN1 lead to a significant change in RP11-390B4.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of LINC01137 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of LINC01137 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is measured. Determine whether ATP6V1B2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is measured. Determine whether ATP6V1B2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of HOTAIRM1. Does perturbing QARS lead to a significant change in HOTAIRM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of HOTAIRM1. Does perturbing QARS lead to a significant change in HOTAIRM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EXOC3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EXOC3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TSPAN33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TSPAN33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4738,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor MTPN expression. Decide whether this perturbation leads to a significant alteration in MTPN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor MTPN expression. Decide whether this perturbation leads to a significant alteration in MTPN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Determine whether VPS41 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Determine whether VPS41 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3490,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Does this perturbation cause a significant change in DST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Does this perturbation cause a significant change in DST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC008074.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC008074.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and APOBEC3D expression is quantified. Does this perturbation result in a significant change in APOBEC3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and APOBEC3D expression is quantified. Does this perturbation result in a significant change in APOBEC3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2460,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Does this perturbation cause a significant change in NUFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Does this perturbation cause a significant change in NUFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and KCTD19 expression is measured. Determine whether KCTD19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and KCTD19 expression is measured. Determine whether KCTD19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4970,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3770,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Does this perturbation cause a significant change in ZNF341 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Does this perturbation cause a significant change in ZNF341 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and KCTD1 expression is quantified. Does this perturbation result in a significant change in KCTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and KCTD1 expression is quantified. Does this perturbation result in a significant change in KCTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4900,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Does this perturbation cause a significant change in CHD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Does this perturbation cause a significant change in CHD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Determine whether FGF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Determine whether FGF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and JARID2 expression is quantified. Does this perturbation result in a significant change in JARID2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and JARID2 expression is quantified. Does this perturbation result in a significant change in JARID2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
308,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor RP11-423O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-423O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor RP11-423O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-423O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-363D14.1. Does perturbing EIF2B2 lead to a significant change in RP11-363D14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-363D14.1. Does perturbing EIF2B2 lead to a significant change in RP11-363D14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5048,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5060,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2178,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor LRRC4B expression. Decide whether this perturbation leads to a significant alteration in LRRC4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor LRRC4B expression. Decide whether this perturbation leads to a significant alteration in LRRC4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3233,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RP11-16E12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-16E12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RP11-16E12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-16E12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is measured. Determine whether RP3-465N24.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is measured. Determine whether RP3-465N24.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4548,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3358,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EXOC3L2 expression. Decide whether this perturbation leads to a significant alteration in EXOC3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EXOC3L2 expression. Decide whether this perturbation leads to a significant alteration in EXOC3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and CTNNB1 expression is quantified. Does this perturbation result in a significant change in CTNNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and CTNNB1 expression is quantified. Does this perturbation result in a significant change in CTNNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2923,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AC007038.7 expression is observed. Does this perturbation lead to a significant difference in AC007038.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AC007038.7 expression is observed. Does this perturbation lead to a significant difference in AC007038.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
678,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor MEX3B expression. Decide whether this perturbation leads to a significant alteration in MEX3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor MEX3B expression. Decide whether this perturbation leads to a significant alteration in MEX3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2748,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor DUSP21 expression. Decide whether this perturbation leads to a significant alteration in DUSP21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor DUSP21 expression. Decide whether this perturbation leads to a significant alteration in DUSP21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1603,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ATP6V1B2 expression is observed. Does this perturbation lead to a significant difference in ATP6V1B2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ATP6V1B2 expression is observed. Does this perturbation lead to a significant difference in ATP6V1B2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4210,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4938,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ATXN7L3B expression. Decide whether this perturbation leads to a significant alteration in ATXN7L3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ATXN7L3B expression. Decide whether this perturbation leads to a significant alteration in ATXN7L3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ATP11B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ATP11B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in PLB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in PLB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Determine whether SLC25A35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Determine whether SLC25A35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
978,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of HIST1H2BC. Does this perturbation cause a significant change in HIST1H2BC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of HIST1H2BC. Does this perturbation cause a significant change in HIST1H2BC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1593,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and LBX1 expression is observed. Does this perturbation lead to a significant difference in LBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and LBX1 expression is observed. Does this perturbation lead to a significant difference in LBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5013,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and THBS1 expression is observed. Does this perturbation lead to a significant difference in THBS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and THBS1 expression is observed. Does this perturbation lead to a significant difference in THBS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of MORF4L2. Does this perturbation cause a significant change in MORF4L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of MORF4L2. Does this perturbation cause a significant change in MORF4L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Determine whether AC012594.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Determine whether AC012594.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4730,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Does this perturbation cause a significant change in MTPN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Does this perturbation cause a significant change in MTPN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Determine whether NXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Determine whether NXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
938,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-863K10.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-863K10.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-863K10.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-863K10.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1878,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC096559.1 expression. Decide whether this perturbation leads to a significant alteration in AC096559.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC096559.1 expression. Decide whether this perturbation leads to a significant alteration in AC096559.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4773,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and HIST1H2BC expression is observed. Does this perturbation lead to a significant difference in HIST1H2BC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and HIST1H2BC expression is observed. Does this perturbation lead to a significant difference in HIST1H2BC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Determine whether TGOLN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Determine whether TGOLN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of PDRG1. Does perturbing COPB1 lead to a significant change in PDRG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of PDRG1. Does perturbing COPB1 lead to a significant change in PDRG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is measured. Determine whether CYP17A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is measured. Determine whether CYP17A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of H1FX. Does this perturbation cause a significant change in H1FX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of H1FX. Does this perturbation cause a significant change in H1FX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1118,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor GOT1 expression. Decide whether this perturbation leads to a significant alteration in GOT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor GOT1 expression. Decide whether this perturbation leads to a significant alteration in GOT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3010,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of DDX6. Does perturbing IER3IP1 lead to a significant change in DDX6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of DDX6. Does perturbing IER3IP1 lead to a significant change in DDX6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4953,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and PLB1 expression is observed. Does this perturbation lead to a significant difference in PLB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and PLB1 expression is observed. Does this perturbation lead to a significant difference in PLB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Determine whether RP11-640M9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Determine whether RP11-640M9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RAI14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RAI14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in KANSL1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in KANSL1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA0922 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA0922 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1330,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Does this perturbation cause a significant change in RCBTB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Does this perturbation cause a significant change in RCBTB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3208,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor GSN expression. Decide whether this perturbation leads to a significant alteration in GSN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor GSN expression. Decide whether this perturbation leads to a significant alteration in GSN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AC007038.7 expression is measured. Determine whether AC007038.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AC007038.7 expression is measured. Determine whether AC007038.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3778,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ZNF341 expression. Decide whether this perturbation leads to a significant alteration in ZNF341 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ZNF341 expression. Decide whether this perturbation leads to a significant alteration in ZNF341 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3563,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3278,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor TSC22D4 expression. Decide whether this perturbation leads to a significant alteration in TSC22D4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor TSC22D4 expression. Decide whether this perturbation leads to a significant alteration in TSC22D4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-863K10.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-863K10.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2548,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ZP3 expression. Decide whether this perturbation leads to a significant alteration in ZP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ZP3 expression. Decide whether this perturbation leads to a significant alteration in ZP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Determine whether RP11-381O7.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Determine whether RP11-381O7.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
473,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and RP11-146D12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-146D12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and RP11-146D12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-146D12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and GDF11 expression is measured. Determine whether GDF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and GDF11 expression is measured. Determine whether GDF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1723,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4748,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PAXBP1 expression. Decide whether this perturbation leads to a significant alteration in PAXBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PAXBP1 expression. Decide whether this perturbation leads to a significant alteration in PAXBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TUBA1C expression is quantified. Does this perturbation result in a significant change in TUBA1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TUBA1C expression is quantified. Does this perturbation result in a significant change in TUBA1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Determine whether ZXDA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Determine whether ZXDA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in CCRL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in CCRL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of C17orf64. Does this perturbation cause a significant change in C17orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of C17orf64. Does this perturbation cause a significant change in C17orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Determine whether ATP6AP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Determine whether ATP6AP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5023,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and RP11-430H10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-430H10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and RP11-430H10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-430H10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4030,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Does this perturbation cause a significant change in NTRK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Does this perturbation cause a significant change in NTRK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1850,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Does this perturbation cause a significant change in TRAPPC10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Does this perturbation cause a significant change in TRAPPC10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2743,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and DUSP21 expression is observed. Does this perturbation lead to a significant difference in DUSP21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and DUSP21 expression is observed. Does this perturbation lead to a significant difference in DUSP21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EPS15. Does perturbing XRN1 lead to a significant change in EPS15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EPS15. Does perturbing XRN1 lead to a significant change in EPS15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Determine whether AKAP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Determine whether AKAP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2010,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Does this perturbation cause a significant change in AC015987.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Does this perturbation cause a significant change in AC015987.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and RP11-434H6.6 expression is quantified. Does this perturbation result in a significant change in RP11-434H6.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and RP11-434H6.6 expression is quantified. Does this perturbation result in a significant change in RP11-434H6.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
188,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor STC2 expression. Decide whether this perturbation leads to a significant alteration in STC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor STC2 expression. Decide whether this perturbation leads to a significant alteration in STC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4570,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3313,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EGLN3 expression is observed. Does this perturbation lead to a significant difference in EGLN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EGLN3 expression is observed. Does this perturbation lead to a significant difference in EGLN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of PPM1N. Does perturbing SLC35B1 lead to a significant change in PPM1N expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of PPM1N. Does perturbing SLC35B1 lead to a significant change in PPM1N expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of AC079466.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of AC079466.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and GOT1 expression is quantified. Does this perturbation result in a significant change in GOT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and GOT1 expression is quantified. Does this perturbation result in a significant change in GOT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RP11-360L9.8. Does perturbing HSD17B12 lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RP11-360L9.8. Does perturbing HSD17B12 lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KIAA1586 expression is quantified. Does this perturbation result in a significant change in KIAA1586 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KIAA1586 expression is quantified. Does this perturbation result in a significant change in KIAA1586 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of RP11-254F7.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of RP11-254F7.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ANXA4 expression is measured. Determine whether ANXA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ANXA4 expression is measured. Determine whether ANXA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4453,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
793,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and REST expression is observed. Does this perturbation lead to a significant difference in REST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and REST expression is observed. Does this perturbation lead to a significant difference in REST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ANPEP. Does perturbing DNAJC19 lead to a significant change in ANPEP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ANPEP. Does perturbing DNAJC19 lead to a significant change in ANPEP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of KIF4A. Does perturbing SEC63 lead to a significant change in KIF4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of KIF4A. Does perturbing SEC63 lead to a significant change in KIF4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in SOBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in SOBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Determine whether MORF4L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Determine whether MORF4L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ZCCHC11. Does this perturbation cause a significant change in ZCCHC11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ZCCHC11. Does this perturbation cause a significant change in ZCCHC11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of TACC3. Does this perturbation cause a significant change in TACC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of TACC3. Does this perturbation cause a significant change in TACC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IFNGR1. Does this perturbation cause a significant change in IFNGR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IFNGR1. Does this perturbation cause a significant change in IFNGR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Determine whether RP11-16E12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Determine whether RP11-16E12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of RP11-666A20.4. Does this perturbation cause a significant change in RP11-666A20.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of RP11-666A20.4. Does this perturbation cause a significant change in RP11-666A20.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of NOSTRIN. Does perturbing SRPRB lead to a significant change in NOSTRIN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of NOSTRIN. Does perturbing SRPRB lead to a significant change in NOSTRIN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1900,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Does this perturbation cause a significant change in AC008074.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Does this perturbation cause a significant change in AC008074.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3890,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Does this perturbation cause a significant change in ACRV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Does this perturbation cause a significant change in ACRV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2818,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDKN2C expression. Decide whether this perturbation leads to a significant alteration in CDKN2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDKN2C expression. Decide whether this perturbation leads to a significant alteration in CDKN2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and UBE3A expression is quantified. Does this perturbation result in a significant change in UBE3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and UBE3A expression is quantified. Does this perturbation result in a significant change in UBE3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3218,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TTC32 expression. Decide whether this perturbation leads to a significant alteration in TTC32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TTC32 expression. Decide whether this perturbation leads to a significant alteration in TTC32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
593,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PSMD14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PSMD14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of SPINK5. Does perturbing EIF2B4 lead to a significant change in SPINK5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of SPINK5. Does perturbing EIF2B4 lead to a significant change in SPINK5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and MORF4L2 expression is measured. Determine whether MORF4L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and MORF4L2 expression is measured. Determine whether MORF4L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DOK3. Does this perturbation cause a significant change in DOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DOK3. Does this perturbation cause a significant change in DOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3398,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TUBA1C expression. Decide whether this perturbation leads to a significant alteration in TUBA1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TUBA1C expression. Decide whether this perturbation leads to a significant alteration in TUBA1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5003,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2328,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor H3F3B expression. Decide whether this perturbation leads to a significant alteration in H3F3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor H3F3B expression. Decide whether this perturbation leads to a significant alteration in H3F3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of SNHG7. Does this perturbation cause a significant change in SNHG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of SNHG7. Does this perturbation cause a significant change in SNHG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2963,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CPQ expression is observed. Does this perturbation lead to a significant difference in CPQ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CPQ expression is observed. Does this perturbation lead to a significant difference in CPQ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ZCCHC11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ZCCHC11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1380,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Does this perturbation cause a significant change in ZEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Does this perturbation cause a significant change in ZEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CPQ. Does this perturbation cause a significant change in CPQ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CPQ. Does this perturbation cause a significant change in CPQ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in PAK1IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in PAK1IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDKN2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDKN2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SIGLEC6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SIGLEC6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1223,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and UBE3A expression is observed. Does this perturbation lead to a significant difference in UBE3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and UBE3A expression is observed. Does this perturbation lead to a significant difference in UBE3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of RP11-434H6.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of RP11-434H6.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and LDLR expression is measured. Determine whether LDLR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and LDLR expression is measured. Determine whether LDLR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is measured. Determine whether ARHGAP11A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is measured. Determine whether ARHGAP11A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-789C1.1 expression is quantified. Does this perturbation result in a significant change in RP11-789C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-789C1.1 expression is quantified. Does this perturbation result in a significant change in RP11-789C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of HLA-E. Does perturbing HSPA5 lead to a significant change in HLA-E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of HLA-E. Does perturbing HSPA5 lead to a significant change in HLA-E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and KIAA1731 expression is quantified. Does this perturbation result in a significant change in KIAA1731 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and KIAA1731 expression is quantified. Does this perturbation result in a significant change in KIAA1731 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CTBS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CTBS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and PTBP3 expression is measured. Determine whether PTBP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and PTBP3 expression is measured. Determine whether PTBP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of GPRC5C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of GPRC5C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is quantified. Does this perturbation result in a significant change in RP11-61E11.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is quantified. Does this perturbation result in a significant change in RP11-61E11.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HMGCS1. Does perturbing EIF2B4 lead to a significant change in HMGCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HMGCS1. Does perturbing EIF2B4 lead to a significant change in HMGCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of RP11-95O2.5. Does perturbing PPWD1 lead to a significant change in RP11-95O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of RP11-95O2.5. Does perturbing PPWD1 lead to a significant change in RP11-95O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and ZC3H7A expression is measured. Determine whether ZC3H7A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and ZC3H7A expression is measured. Determine whether ZC3H7A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of LINC01137. Does this perturbation cause a significant change in LINC01137 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of LINC01137. Does this perturbation cause a significant change in LINC01137 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in PGM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in PGM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
900,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Does this perturbation cause a significant change in PRRC2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Does this perturbation cause a significant change in PRRC2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MLEC expression is quantified. Does this perturbation result in a significant change in MLEC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MLEC expression is quantified. Does this perturbation result in a significant change in MLEC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of NXF1. Does perturbing SARS lead to a significant change in NXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of NXF1. Does perturbing SARS lead to a significant change in NXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3413,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and NOX5 expression is observed. Does this perturbation lead to a significant difference in NOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and NOX5 expression is observed. Does this perturbation lead to a significant difference in NOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in RP11-181G12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in RP11-181G12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
250,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Does this perturbation cause a significant change in LINC00657 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Does this perturbation cause a significant change in LINC00657 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is quantified. Does this perturbation result in a significant change in HIST1H2BC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is quantified. Does this perturbation result in a significant change in HIST1H2BC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1590,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Does this perturbation cause a significant change in LBX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Does this perturbation cause a significant change in LBX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Determine whether LTBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Determine whether LTBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4288,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SETD5-AS1. Does this perturbation cause a significant change in SETD5-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SETD5-AS1. Does this perturbation cause a significant change in SETD5-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of SBF2. Does perturbing FARSB lead to a significant change in SBF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of SBF2. Does perturbing FARSB lead to a significant change in SBF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and LIMS1 expression is quantified. Does this perturbation result in a significant change in LIMS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and LIMS1 expression is quantified. Does this perturbation result in a significant change in LIMS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PTPN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PTPN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of RP11-471M2.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of RP11-471M2.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3178,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MLEC expression. Decide whether this perturbation leads to a significant alteration in MLEC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MLEC expression. Decide whether this perturbation leads to a significant alteration in MLEC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
228,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor CASP8 expression. Decide whether this perturbation leads to a significant alteration in CASP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor CASP8 expression. Decide whether this perturbation leads to a significant alteration in CASP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3363,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in JUND expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in JUND expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Determine whether DNMBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Determine whether DNMBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of MTPN. Does perturbing SEC61G lead to a significant change in MTPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of MTPN. Does perturbing SEC61G lead to a significant change in MTPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3648,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor RP11-3D4.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-3D4.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor RP11-3D4.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-3D4.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in F2RL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in F2RL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of WARS. Does perturbing CARS lead to a significant change in WARS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of WARS. Does perturbing CARS lead to a significant change in WARS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in PKDCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in PKDCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Determine whether PTGS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Determine whether PTGS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4060,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Does this perturbation cause a significant change in CENPF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Does this perturbation cause a significant change in CENPF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5043,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of HIST1H1D. Does perturbing SRPRB lead to a significant change in HIST1H1D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of HIST1H1D. Does perturbing SRPRB lead to a significant change in HIST1H1D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and LBX1 expression is measured. Determine whether LBX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and LBX1 expression is measured. Determine whether LBX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
930,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Does this perturbation cause a significant change in RP11-863K10.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Does this perturbation cause a significant change in RP11-863K10.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of DNASE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of DNASE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is measured. Determine whether RP11-2H8.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is measured. Determine whether RP11-2H8.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TKTL1. Does perturbing BHLHE40 lead to a significant change in TKTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TKTL1. Does perturbing BHLHE40 lead to a significant change in TKTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in TAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in TAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and NPAT expression is quantified. Does this perturbation result in a significant change in NPAT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and NPAT expression is quantified. Does this perturbation result in a significant change in NPAT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ARSA. Does this perturbation cause a significant change in ARSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ARSA. Does this perturbation cause a significant change in ARSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1140,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Does this perturbation cause a significant change in SP100 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Does this perturbation cause a significant change in SP100 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ERP29 expression is measured. Determine whether ERP29 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ERP29 expression is measured. Determine whether ERP29 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of C1GALT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of C1GALT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4428,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RP11-157D23.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-157D23.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RP11-157D23.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-157D23.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of MARCH8. Does perturbing SAMM50 lead to a significant change in MARCH8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of MARCH8. Does perturbing SAMM50 lead to a significant change in MARCH8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
728,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor RP11-132A1.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-132A1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor RP11-132A1.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-132A1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4128,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor FOXO6 expression. Decide whether this perturbation leads to a significant alteration in FOXO6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor FOXO6 expression. Decide whether this perturbation leads to a significant alteration in FOXO6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
8,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ZNF429 expression. Decide whether this perturbation leads to a significant alteration in ZNF429 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ZNF429 expression. Decide whether this perturbation leads to a significant alteration in ZNF429 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4093,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and DSC2 expression is observed. Does this perturbation lead to a significant difference in DSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and DSC2 expression is observed. Does this perturbation lead to a significant difference in DSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is quantified. Does this perturbation result in a significant change in RP11-81A22.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is quantified. Does this perturbation result in a significant change in RP11-81A22.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RASGRP2 expression is quantified. Does this perturbation result in a significant change in RASGRP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RASGRP2 expression is quantified. Does this perturbation result in a significant change in RASGRP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ANPEP expression is measured. Determine whether ANPEP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ANPEP expression is measured. Determine whether ANPEP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and TIPARP expression is measured. Determine whether TIPARP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and TIPARP expression is measured. Determine whether TIPARP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in SHOX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in SHOX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
82,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and PHF3 expression is quantified. Does this perturbation result in a significant change in PHF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and PHF3 expression is quantified. Does this perturbation result in a significant change in PHF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3613,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and TIPARP expression is observed. Does this perturbation lead to a significant difference in TIPARP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and TIPARP expression is observed. Does this perturbation lead to a significant difference in TIPARP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of PELO. Does perturbing TMED10 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of PELO. Does perturbing TMED10 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and LINC01137 expression is quantified. Does this perturbation result in a significant change in LINC01137 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and LINC01137 expression is quantified. Does this perturbation result in a significant change in LINC01137 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of RTN2. Does perturbing TTI2 lead to a significant change in RTN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of RTN2. Does perturbing TTI2 lead to a significant change in RTN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4168,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor SSBP2 expression. Decide whether this perturbation leads to a significant alteration in SSBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor SSBP2 expression. Decide whether this perturbation leads to a significant alteration in SSBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3238,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RP11-16E12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-16E12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RP11-16E12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-16E12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and FOXO6 expression is measured. Determine whether FOXO6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and FOXO6 expression is measured. Determine whether FOXO6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CPQ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CPQ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4463,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and NAV1 expression is observed. Does this perturbation lead to a significant difference in NAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and NAV1 expression is observed. Does this perturbation lead to a significant difference in NAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3140,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Does this perturbation cause a significant change in DYNC1H1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Does this perturbation cause a significant change in DYNC1H1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and KCTD1 expression is measured. Determine whether KCTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and KCTD1 expression is measured. Determine whether KCTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5018,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor THBS1 expression. Decide whether this perturbation leads to a significant alteration in THBS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor THBS1 expression. Decide whether this perturbation leads to a significant alteration in THBS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is quantified. Does this perturbation result in a significant change in CTD-2020K17.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is quantified. Does this perturbation result in a significant change in CTD-2020K17.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-363D14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-363D14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2688,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor KCTD19 expression. Decide whether this perturbation leads to a significant alteration in KCTD19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor KCTD19 expression. Decide whether this perturbation leads to a significant alteration in KCTD19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of CTD-2267D19.3. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of CTD-2267D19.3. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of KCNJ13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of KCNJ13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of NXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of NXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4813,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and MBNL1 expression is observed. Does this perturbation lead to a significant difference in MBNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and MBNL1 expression is observed. Does this perturbation lead to a significant difference in MBNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1580,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and FAM114A1 expression is measured. Determine whether FAM114A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and FAM114A1 expression is measured. Determine whether FAM114A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and NXF1 expression is quantified. Does this perturbation result in a significant change in NXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and NXF1 expression is quantified. Does this perturbation result in a significant change in NXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and AC012594.1 expression is measured. Determine whether AC012594.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and AC012594.1 expression is measured. Determine whether AC012594.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and CTSF expression is measured. Determine whether CTSF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and CTSF expression is measured. Determine whether CTSF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in NUFIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in NUFIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PDE9A. Does perturbing DDIT3 lead to a significant change in PDE9A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PDE9A. Does perturbing DDIT3 lead to a significant change in PDE9A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in RP11-212I21.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in RP11-212I21.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and C10orf32 expression is measured. Determine whether C10orf32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and C10orf32 expression is measured. Determine whether C10orf32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ATP2A3 expression is quantified. Does this perturbation result in a significant change in ATP2A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ATP2A3 expression is quantified. Does this perturbation result in a significant change in ATP2A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5020,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Does this perturbation cause a significant change in RP11-430H10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Does this perturbation cause a significant change in RP11-430H10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of RP11-132A1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of RP11-132A1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of RP11-81A22.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of RP11-81A22.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
568,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor IL32 expression. Decide whether this perturbation leads to a significant alteration in IL32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor IL32 expression. Decide whether this perturbation leads to a significant alteration in IL32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of SMCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of SMCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in TGOLN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in TGOLN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TRIM38 expression is quantified. Does this perturbation result in a significant change in TRIM38 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TRIM38 expression is quantified. Does this perturbation result in a significant change in TRIM38 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-789C1.1. Does perturbing DARS lead to a significant change in RP11-789C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-789C1.1. Does perturbing DARS lead to a significant change in RP11-789C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of WDR72. Does perturbing UFM1 lead to a significant change in WDR72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of WDR72. Does perturbing UFM1 lead to a significant change in WDR72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Determine whether AP000688.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Determine whether AP000688.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2630,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Does this perturbation cause a significant change in HAGH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Does this perturbation cause a significant change in HAGH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and POU2F2 expression is measured. Determine whether POU2F2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and POU2F2 expression is measured. Determine whether POU2F2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Determine whether RP3-465N24.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Determine whether RP3-465N24.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NUF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NUF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in NTRK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in NTRK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in SEC23IP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in SEC23IP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and RNF139-AS1 expression is quantified. Does this perturbation result in a significant change in RNF139-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and RNF139-AS1 expression is quantified. Does this perturbation result in a significant change in RNF139-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3370,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Does this perturbation cause a significant change in LIMS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Does this perturbation cause a significant change in LIMS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Determine whether RP11-430H10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Determine whether RP11-430H10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of UHRF1BP1L. Does this perturbation cause a significant change in UHRF1BP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of UHRF1BP1L. Does this perturbation cause a significant change in UHRF1BP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Determine whether HM13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Determine whether HM13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EGLN3 expression is measured. Determine whether EGLN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EGLN3 expression is measured. Determine whether EGLN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
26,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ATP2A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ATP2A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Determine whether CDRT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Determine whether CDRT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and USP37 expression is measured. Determine whether USP37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and USP37 expression is measured. Determine whether USP37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of NINJ2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of NINJ2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4283,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Determine whether TRPM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Determine whether TRPM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of LBX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of LBX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of TOPBP1. Does perturbing TARS lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of TOPBP1. Does perturbing TARS lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and WHAMM expression is measured. Determine whether WHAMM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and WHAMM expression is measured. Determine whether WHAMM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5080,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Does this perturbation cause a significant change in GPR146 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Does this perturbation cause a significant change in GPR146 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IFT27 expression is quantified. Does this perturbation result in a significant change in IFT27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IFT27 expression is quantified. Does this perturbation result in a significant change in IFT27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
49,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and LPAR5 expression is measured. Determine whether LPAR5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and LPAR5 expression is measured. Determine whether LPAR5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of CENPF. Does perturbing CCND3 lead to a significant change in CENPF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of CENPF. Does perturbing CCND3 lead to a significant change in CENPF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
520,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Does this perturbation cause a significant change in DDX6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Does this perturbation cause a significant change in DDX6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Determine whether KIF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Determine whether KIF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ZC3H7A expression is quantified. Does this perturbation result in a significant change in ZC3H7A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ZC3H7A expression is quantified. Does this perturbation result in a significant change in ZC3H7A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in GATA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in GATA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of DDIT4. Does perturbing GMPPB lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of DDIT4. Does perturbing GMPPB lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SETD5-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SETD5-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and C9orf64 expression is measured. Determine whether C9orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and C9orf64 expression is measured. Determine whether C9orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1028,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HIST1H1E expression. Decide whether this perturbation leads to a significant alteration in HIST1H1E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HIST1H1E expression. Decide whether this perturbation leads to a significant alteration in HIST1H1E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
150,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Does this perturbation cause a significant change in CTSF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Does this perturbation cause a significant change in CTSF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of CENPF. Does this perturbation cause a significant change in CENPF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of CENPF. Does this perturbation cause a significant change in CENPF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4078,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP1-274L7.1 expression. Decide whether this perturbation leads to a significant alteration in RP1-274L7.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP1-274L7.1 expression. Decide whether this perturbation leads to a significant alteration in RP1-274L7.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and GATA2 expression is quantified. Does this perturbation result in a significant change in GATA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and GATA2 expression is quantified. Does this perturbation result in a significant change in GATA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC096559.1 expression is measured. Determine whether AC096559.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC096559.1 expression is measured. Determine whether AC096559.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ARHGAP30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ARHGAP30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of HLA-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of HLA-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
683,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ARSA expression is observed. Does this perturbation lead to a significant difference in ARSA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ARSA expression is observed. Does this perturbation lead to a significant difference in ARSA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TKTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TKTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PHF19. Does perturbing SARS lead to a significant change in PHF19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PHF19. Does perturbing SARS lead to a significant change in PHF19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4213,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and CD46 expression is observed. Does this perturbation lead to a significant difference in CD46 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and CD46 expression is observed. Does this perturbation lead to a significant difference in CD46 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is measured. Determine whether CTD-2521M24.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is measured. Determine whether CTD-2521M24.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RNF8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RNF8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ADAMTS10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ADAMTS10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4028,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor PIK3R3 expression. Decide whether this perturbation leads to a significant alteration in PIK3R3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor PIK3R3 expression. Decide whether this perturbation leads to a significant alteration in PIK3R3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in TSNAXIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in TSNAXIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Determine whether RNF19A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Determine whether RNF19A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
648,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor KANSL1L expression. Decide whether this perturbation leads to a significant alteration in KANSL1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor KANSL1L expression. Decide whether this perturbation leads to a significant alteration in KANSL1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ANKRD11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ANKRD11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1253,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and IL8 expression is observed. Does this perturbation lead to a significant difference in IL8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and IL8 expression is observed. Does this perturbation lead to a significant difference in IL8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in UBE3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in UBE3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of ARHGDIB. Does perturbing TMEM167A lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of ARHGDIB. Does perturbing TMEM167A lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of RP11-445H22.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of RP11-445H22.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of KHDC1L. Does this perturbation cause a significant change in KHDC1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of KHDC1L. Does this perturbation cause a significant change in KHDC1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of PBDC1. Does perturbing HARS lead to a significant change in PBDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of PBDC1. Does perturbing HARS lead to a significant change in PBDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4348,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor HIST1H1D expression. Decide whether this perturbation leads to a significant alteration in HIST1H1D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor HIST1H1D expression. Decide whether this perturbation leads to a significant alteration in HIST1H1D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2063,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and RTN2 expression is observed. Does this perturbation lead to a significant difference in RTN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and RTN2 expression is observed. Does this perturbation lead to a significant difference in RTN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ERV3-1 expression is measured. Determine whether ERV3-1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ERV3-1 expression is measured. Determine whether ERV3-1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3753,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA1432 expression is observed. Does this perturbation lead to a significant difference in KIAA1432 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA1432 expression is observed. Does this perturbation lead to a significant difference in KIAA1432 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3883,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and RP11-573D15.2 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and RP11-573D15.2 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of WHSC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of WHSC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CHD3. Does perturbing CARS lead to a significant change in CHD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CHD3. Does perturbing CARS lead to a significant change in CHD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4770,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Does this perturbation cause a significant change in HIST1H2BC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Does this perturbation cause a significant change in HIST1H2BC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1378,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor KCTD1 expression. Decide whether this perturbation leads to a significant alteration in KCTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor KCTD1 expression. Decide whether this perturbation leads to a significant alteration in KCTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of OXLD1. Does this perturbation cause a significant change in OXLD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of OXLD1. Does this perturbation cause a significant change in OXLD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Determine whether RBM12B-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Determine whether RBM12B-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4933,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ATXN7L3B expression is observed. Does this perturbation lead to a significant difference in ATXN7L3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ATXN7L3B expression is observed. Does this perturbation lead to a significant difference in ATXN7L3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is measured. Determine whether RP11-61E11.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is measured. Determine whether RP11-61E11.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
450,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Does this perturbation cause a significant change in SLFNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Does this perturbation cause a significant change in SLFNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-499F3.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-499F3.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3698,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor TTC18 expression. Decide whether this perturbation leads to a significant alteration in TTC18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor TTC18 expression. Decide whether this perturbation leads to a significant alteration in TTC18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP5 expression is quantified. Does this perturbation result in a significant change in ARHGAP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP5 expression is quantified. Does this perturbation result in a significant change in ARHGAP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Determine whether RP11-573D15.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Determine whether RP11-573D15.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3348,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SIGLEC6 expression. Decide whether this perturbation leads to a significant alteration in SIGLEC6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SIGLEC6 expression. Decide whether this perturbation leads to a significant alteration in SIGLEC6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in VPS41 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in VPS41 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP3-465N24.6. Does perturbing SRP68 lead to a significant change in RP3-465N24.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP3-465N24.6. Does perturbing SRP68 lead to a significant change in RP3-465N24.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
430,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Does this perturbation cause a significant change in CLINT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Does this perturbation cause a significant change in CLINT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1078,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ADAMTS10 expression. Decide whether this perturbation leads to a significant alteration in ADAMTS10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ADAMTS10 expression. Decide whether this perturbation leads to a significant alteration in ADAMTS10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RAI14 expression is measured. Determine whether RAI14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RAI14 expression is measured. Determine whether RAI14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of NPAT. Does this perturbation cause a significant change in NPAT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of NPAT. Does this perturbation cause a significant change in NPAT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ZEB1 expression is quantified. Does this perturbation result in a significant change in ZEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ZEB1 expression is quantified. Does this perturbation result in a significant change in ZEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
223,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and CASP8 expression is observed. Does this perturbation lead to a significant difference in CASP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and CASP8 expression is observed. Does this perturbation lead to a significant difference in CASP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4220,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Does this perturbation cause a significant change in IFT27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Does this perturbation cause a significant change in IFT27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ROBO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ROBO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1060,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Does this perturbation cause a significant change in KHDC1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Does this perturbation cause a significant change in KHDC1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Determine whether ANKRD11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Determine whether ANKRD11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3863,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1873,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC096559.1 expression is observed. Does this perturbation lead to a significant difference in AC096559.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC096559.1 expression is observed. Does this perturbation lead to a significant difference in AC096559.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and RNF19A expression is measured. Determine whether RNF19A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and RNF19A expression is measured. Determine whether RNF19A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of OPTN. Does perturbing YIPF5 lead to a significant change in OPTN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of OPTN. Does perturbing YIPF5 lead to a significant change in OPTN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
48,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor LPAR5 expression. Decide whether this perturbation leads to a significant alteration in LPAR5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor LPAR5 expression. Decide whether this perturbation leads to a significant alteration in LPAR5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TKTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TKTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Determine whether ANKRD33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Determine whether ANKRD33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and F2RL2 expression is measured. Determine whether F2RL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and F2RL2 expression is measured. Determine whether F2RL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP11-2H8.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP11-2H8.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of RP11-304M2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of RP11-304M2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2580,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Does this perturbation cause a significant change in KIF4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Does this perturbation cause a significant change in KIF4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Determine whether SMIM14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Determine whether SMIM14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and MARCH8 expression is quantified. Does this perturbation result in a significant change in MARCH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and MARCH8 expression is quantified. Does this perturbation result in a significant change in MARCH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
838,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor RP11-138C9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-138C9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor RP11-138C9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-138C9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is quantified. Does this perturbation result in a significant change in RP11-640M9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is quantified. Does this perturbation result in a significant change in RP11-640M9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RDH10 expression is measured. Determine whether RDH10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RDH10 expression is measured. Determine whether RDH10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-499F3.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-499F3.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DUT. Does this perturbation cause a significant change in DUT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DUT. Does this perturbation cause a significant change in DUT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Determine whether SBF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Determine whether SBF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Determine whether ZFP36L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Determine whether ZFP36L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EIF3A. Does this perturbation cause a significant change in EIF3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EIF3A. Does this perturbation cause a significant change in EIF3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CHD3 expression is quantified. Does this perturbation result in a significant change in CHD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CHD3 expression is quantified. Does this perturbation result in a significant change in CHD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4618,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor P4HB expression. Decide whether this perturbation leads to a significant alteration in P4HB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor P4HB expression. Decide whether this perturbation leads to a significant alteration in P4HB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in FAM212A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in FAM212A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of PDRG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of PDRG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EPS15 expression is measured. Determine whether EPS15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EPS15 expression is measured. Determine whether EPS15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3463,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CHST12 expression is observed. Does this perturbation lead to a significant difference in CHST12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CHST12 expression is observed. Does this perturbation lead to a significant difference in CHST12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SP100. Does perturbing UFL1 lead to a significant change in SP100 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SP100. Does perturbing UFL1 lead to a significant change in SP100 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3393,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TUBA1C expression is observed. Does this perturbation lead to a significant difference in TUBA1C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TUBA1C expression is observed. Does this perturbation lead to a significant difference in TUBA1C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of SNHG7. Does perturbing CCND3 lead to a significant change in SNHG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of SNHG7. Does perturbing CCND3 lead to a significant change in SNHG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2313,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ANKLE2 expression is observed. Does this perturbation lead to a significant difference in ANKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ANKLE2 expression is observed. Does this perturbation lead to a significant difference in ANKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2998,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CTD-2521M24.9 expression. Decide whether this perturbation leads to a significant alteration in CTD-2521M24.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CTD-2521M24.9 expression. Decide whether this perturbation leads to a significant alteration in CTD-2521M24.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
240,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Does this perturbation cause a significant change in UHRF1BP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Does this perturbation cause a significant change in UHRF1BP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in C3AR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in C3AR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
478,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor RP11-146D12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-146D12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor RP11-146D12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-146D12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ITGB2 expression is measured. Determine whether ITGB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ITGB2 expression is measured. Determine whether ITGB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ANKRD10 expression is measured. Determine whether ANKRD10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ANKRD10 expression is measured. Determine whether ANKRD10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2130,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Does this perturbation cause a significant change in SLBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Does this perturbation cause a significant change in SLBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DUT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DUT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
25,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
768,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor HLA-AS1 expression. Decide whether this perturbation leads to a significant alteration in HLA-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor HLA-AS1 expression. Decide whether this perturbation leads to a significant alteration in HLA-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ATP11B. Does perturbing OST4 lead to a significant change in ATP11B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ATP11B. Does perturbing OST4 lead to a significant change in ATP11B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Determine whether RP11-212I21.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Determine whether RP11-212I21.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
590,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1478,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ARHGAP30 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP30 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ARHGAP30 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP30 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2218,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4918,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CMTM6 expression. Decide whether this perturbation leads to a significant alteration in CMTM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CMTM6 expression. Decide whether this perturbation leads to a significant alteration in CMTM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and SERPINH1 expression is measured. Determine whether SERPINH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and SERPINH1 expression is measured. Determine whether SERPINH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in MS4A6E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in MS4A6E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of VPS41 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of VPS41 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of LINC00657 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of LINC00657 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2350,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Does this perturbation cause a significant change in IL13RA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Does this perturbation cause a significant change in IL13RA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3603,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and C10orf32 expression is quantified. Does this perturbation result in a significant change in C10orf32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and C10orf32 expression is quantified. Does this perturbation result in a significant change in C10orf32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
248,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor UHRF1BP1L expression. Decide whether this perturbation leads to a significant alteration in UHRF1BP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor UHRF1BP1L expression. Decide whether this perturbation leads to a significant alteration in UHRF1BP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2760,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Does this perturbation cause a significant change in CDK13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Does this perturbation cause a significant change in CDK13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and PPM1N expression is quantified. Does this perturbation result in a significant change in PPM1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and PPM1N expression is quantified. Does this perturbation result in a significant change in PPM1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and KCNE3 expression is measured. Determine whether KCNE3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and KCNE3 expression is measured. Determine whether KCNE3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
853,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ATF6 expression is observed. Does this perturbation lead to a significant difference in ATF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ATF6 expression is observed. Does this perturbation lead to a significant difference in ATF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1500,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP3-465N24.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP3-465N24.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in REST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in REST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ARSA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ARSA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1820,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Does this perturbation cause a significant change in DDIT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Does this perturbation cause a significant change in DDIT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
530,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Does this perturbation cause a significant change in IRF7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Does this perturbation cause a significant change in IRF7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
948,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-789C1.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-789C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-789C1.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-789C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RAI14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RAI14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
723,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and RP11-132A1.4 expression is observed. Does this perturbation lead to a significant difference in RP11-132A1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and RP11-132A1.4 expression is observed. Does this perturbation lead to a significant difference in RP11-132A1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1983,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and KLF3 expression is observed. Does this perturbation lead to a significant difference in KLF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and KLF3 expression is observed. Does this perturbation lead to a significant difference in KLF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in AKAP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in AKAP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of TROAP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of TROAP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of SBF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of SBF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and LIMS1 expression is measured. Determine whether LIMS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and LIMS1 expression is measured. Determine whether LIMS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is quantified. Does this perturbation result in a significant change in CTD-2521M24.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is quantified. Does this perturbation result in a significant change in CTD-2521M24.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and HP1BP3 expression is quantified. Does this perturbation result in a significant change in HP1BP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and HP1BP3 expression is quantified. Does this perturbation result in a significant change in HP1BP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4613,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and P4HB expression is observed. Does this perturbation lead to a significant difference in P4HB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and P4HB expression is observed. Does this perturbation lead to a significant difference in P4HB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of EXO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of EXO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of SRP72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of SRP72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Determine whether NFE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Determine whether NFE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3160,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Does this perturbation cause a significant change in MT2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Does this perturbation cause a significant change in MT2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KIAA1586 expression is measured. Determine whether KIAA1586 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KIAA1586 expression is measured. Determine whether KIAA1586 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of DST. Does perturbing SCYL1 lead to a significant change in DST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of DST. Does perturbing SCYL1 lead to a significant change in DST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
96,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Determine whether RP11-141B14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Determine whether RP11-141B14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Determine whether IDH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Determine whether IDH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and TMOD3 expression is quantified. Does this perturbation result in a significant change in TMOD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and TMOD3 expression is quantified. Does this perturbation result in a significant change in TMOD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of PTBP3. Does this perturbation cause a significant change in PTBP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of PTBP3. Does this perturbation cause a significant change in PTBP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1868,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor TACC3 expression. Decide whether this perturbation leads to a significant alteration in TACC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor TACC3 expression. Decide whether this perturbation leads to a significant alteration in TACC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is quantified. Does this perturbation result in a significant change in KCNQ1OT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is quantified. Does this perturbation result in a significant change in KCNQ1OT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CMTM6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CMTM6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4413,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and AC005540.3 expression is observed. Does this perturbation lead to a significant difference in AC005540.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and AC005540.3 expression is observed. Does this perturbation lead to a significant difference in AC005540.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1203,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and GMEB1 expression is observed. Does this perturbation lead to a significant difference in GMEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and GMEB1 expression is observed. Does this perturbation lead to a significant difference in GMEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
298,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ATP11B expression. Decide whether this perturbation leads to a significant alteration in ATP11B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ATP11B expression. Decide whether this perturbation leads to a significant alteration in ATP11B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3670,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Does this perturbation cause a significant change in ZC3H7A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Does this perturbation cause a significant change in ZC3H7A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4910,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Does this perturbation cause a significant change in CMTM6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Does this perturbation cause a significant change in CMTM6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2210,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Determine whether IFNGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Determine whether IFNGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Determine whether ATP5EP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Determine whether ATP5EP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AFF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AFF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in GPR146 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in GPR146 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Determine whether CLINT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Determine whether CLINT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ZFP36L2 expression is quantified. Does this perturbation result in a significant change in ZFP36L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ZFP36L2 expression is quantified. Does this perturbation result in a significant change in ZFP36L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of PDK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of PDK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of C12orf44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of C12orf44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2943,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and SKIL expression is observed. Does this perturbation lead to a significant difference in SKIL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and SKIL expression is observed. Does this perturbation lead to a significant difference in SKIL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CTC-308K20.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CTC-308K20.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of FGF11. Does this perturbation cause a significant change in FGF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of FGF11. Does this perturbation cause a significant change in FGF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and NFAT5 expression is quantified. Does this perturbation result in a significant change in NFAT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and NFAT5 expression is quantified. Does this perturbation result in a significant change in NFAT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HIST1H2AM. Does perturbing EIF2B4 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HIST1H2AM. Does perturbing EIF2B4 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4290,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3083,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and TROAP expression is observed. Does this perturbation lead to a significant difference in TROAP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and TROAP expression is observed. Does this perturbation lead to a significant difference in TROAP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ZEB2. Does perturbing IDH3A lead to a significant change in ZEB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ZEB2. Does perturbing IDH3A lead to a significant change in ZEB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2488,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor HLTF expression. Decide whether this perturbation leads to a significant alteration in HLTF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor HLTF expression. Decide whether this perturbation leads to a significant alteration in HLTF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3480,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Does this perturbation cause a significant change in PTGS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Does this perturbation cause a significant change in PTGS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
483,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Determine whether DOCK11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Determine whether DOCK11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Determine whether NTRK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Determine whether NTRK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4240,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Does this perturbation cause a significant change in LINC01031 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Does this perturbation cause a significant change in LINC01031 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Determine whether CDT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Determine whether CDT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and LDLR expression is quantified. Does this perturbation result in a significant change in LDLR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and LDLR expression is quantified. Does this perturbation result in a significant change in LDLR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Determine whether TACC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Determine whether TACC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ZXDA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ZXDA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3853,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and PHF21A expression is observed. Does this perturbation lead to a significant difference in PHF21A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and PHF21A expression is observed. Does this perturbation lead to a significant difference in PHF21A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
98,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-141B14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-141B14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-141B14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-141B14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2673,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CTSV expression is observed. Does this perturbation lead to a significant difference in CTSV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CTSV expression is observed. Does this perturbation lead to a significant difference in CTSV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC008074.3. Does this perturbation cause a significant change in AC008074.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC008074.3. Does this perturbation cause a significant change in AC008074.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4830,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Does this perturbation cause a significant change in RP11-390B4.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Does this perturbation cause a significant change in RP11-390B4.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Determine whether RP13-216E22.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Determine whether RP13-216E22.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3660,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Does this perturbation cause a significant change in EP400 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Does this perturbation cause a significant change in EP400 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4313,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and MED13 expression is observed. Does this perturbation lead to a significant difference in MED13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and MED13 expression is observed. Does this perturbation lead to a significant difference in MED13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1373,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and KCTD1 expression is observed. Does this perturbation lead to a significant difference in KCTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and KCTD1 expression is observed. Does this perturbation lead to a significant difference in KCTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
963,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ZEB2 expression is observed. Does this perturbation lead to a significant difference in ZEB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ZEB2 expression is observed. Does this perturbation lead to a significant difference in ZEB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NPDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NPDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and NINJ2 expression is measured. Determine whether NINJ2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and NINJ2 expression is measured. Determine whether NINJ2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2018,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor AC015987.2 expression. Decide whether this perturbation leads to a significant alteration in AC015987.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor AC015987.2 expression. Decide whether this perturbation leads to a significant alteration in AC015987.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDK13. Does this perturbation cause a significant change in CDK13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDK13. Does this perturbation cause a significant change in CDK13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3448,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CCDC69 expression. Decide whether this perturbation leads to a significant alteration in CCDC69 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CCDC69 expression. Decide whether this perturbation leads to a significant alteration in CCDC69 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EPB42 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EPB42 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP1-274L7.1. Does this perturbation cause a significant change in RP1-274L7.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP1-274L7.1. Does this perturbation cause a significant change in RP1-274L7.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of DYNC1H1. Does this perturbation cause a significant change in DYNC1H1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of DYNC1H1. Does this perturbation cause a significant change in DYNC1H1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in AP000688.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in AP000688.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2663,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ASPM expression is observed. Does this perturbation lead to a significant difference in ASPM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ASPM expression is observed. Does this perturbation lead to a significant difference in ASPM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3033,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-838N2.4 expression is observed. Does this perturbation lead to a significant difference in RP11-838N2.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-838N2.4 expression is observed. Does this perturbation lead to a significant difference in RP11-838N2.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Determine whether GDF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Determine whether GDF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and PLA2G15 expression is measured. Determine whether PLA2G15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and PLA2G15 expression is measured. Determine whether PLA2G15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Determine whether IL8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Determine whether IL8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of RSL24D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of RSL24D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and IRF7 expression is measured. Determine whether IRF7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and IRF7 expression is measured. Determine whether IRF7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2413,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ATXN7L3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ATXN7L3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of OR2T6. Does this perturbation cause a significant change in OR2T6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of OR2T6. Does this perturbation cause a significant change in OR2T6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of ZCCHC11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of ZCCHC11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of TOPBP1. Does perturbing HYOU1 lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of TOPBP1. Does perturbing HYOU1 lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ZNF789. Does perturbing TTI1 lead to a significant change in ZNF789 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ZNF789. Does perturbing TTI1 lead to a significant change in ZNF789 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3148,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor DYNC1H1 expression. Decide whether this perturbation leads to a significant alteration in DYNC1H1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor DYNC1H1 expression. Decide whether this perturbation leads to a significant alteration in DYNC1H1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1403,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4018,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor DNMBP expression. Decide whether this perturbation leads to a significant alteration in DNMBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor DNMBP expression. Decide whether this perturbation leads to a significant alteration in DNMBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
833,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and RP11-138C9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-138C9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and RP11-138C9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-138C9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3353,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EXOC3L2 expression is observed. Does this perturbation lead to a significant difference in EXOC3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EXOC3L2 expression is observed. Does this perturbation lead to a significant difference in EXOC3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in MARCH8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in MARCH8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3388,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TRIM38 expression. Decide whether this perturbation leads to a significant alteration in TRIM38 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TRIM38 expression. Decide whether this perturbation leads to a significant alteration in TRIM38 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DOK3 expression is quantified. Does this perturbation result in a significant change in DOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DOK3 expression is quantified. Does this perturbation result in a significant change in DOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
120,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Determine whether FAM212A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Determine whether FAM212A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and SAMM50 expression is quantified. Does this perturbation result in a significant change in SAMM50 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and SAMM50 expression is quantified. Does this perturbation result in a significant change in SAMM50 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AMOTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AMOTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of UBE3A. Does perturbing DDRGK1 lead to a significant change in UBE3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of UBE3A. Does perturbing DDRGK1 lead to a significant change in UBE3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ABI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ABI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and KLF6 expression is quantified. Does this perturbation result in a significant change in KLF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and KLF6 expression is quantified. Does this perturbation result in a significant change in KLF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in KLK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in KLK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of KIAA1731 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of KIAA1731 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Determine whether GMEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Determine whether GMEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1443,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and AC079466.1 expression is observed. Does this perturbation lead to a significant difference in AC079466.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and AC079466.1 expression is observed. Does this perturbation lead to a significant difference in AC079466.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PSMC1 expression is measured. Determine whether PSMC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PSMC1 expression is measured. Determine whether PSMC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Determine whether HLA-E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Determine whether HLA-E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of IRF7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of IRF7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-499F3.2 expression is quantified. Does this perturbation result in a significant change in RP11-499F3.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-499F3.2 expression is quantified. Does this perturbation result in a significant change in RP11-499F3.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of TRAPPC10. Does this perturbation cause a significant change in TRAPPC10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of TRAPPC10. Does this perturbation cause a significant change in TRAPPC10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Determine whether EXOC3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Determine whether EXOC3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and DNASE2 expression is measured. Determine whether DNASE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and DNASE2 expression is measured. Determine whether DNASE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of FAM212A. Does perturbing NEDD8 lead to a significant change in FAM212A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of FAM212A. Does perturbing NEDD8 lead to a significant change in FAM212A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of PGM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of PGM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GLG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GLG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4508,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor BIRC5 expression. Decide whether this perturbation leads to a significant alteration in BIRC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor BIRC5 expression. Decide whether this perturbation leads to a significant alteration in BIRC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in SMCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in SMCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in BRWD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in BRWD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2118,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3040,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Does this perturbation cause a significant change in C10orf32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Does this perturbation cause a significant change in C10orf32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
968,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ZEB2 expression. Decide whether this perturbation leads to a significant alteration in ZEB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ZEB2 expression. Decide whether this perturbation leads to a significant alteration in ZEB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Determine whether USP34 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Determine whether USP34 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ZNF678 expression is quantified. Does this perturbation result in a significant change in ZNF678 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ZNF678 expression is quantified. Does this perturbation result in a significant change in ZNF678 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and LTBP1 expression is measured. Determine whether LTBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and LTBP1 expression is measured. Determine whether LTBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in DDX6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in DDX6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PIK3IP1 expression is measured. Determine whether PIK3IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PIK3IP1 expression is measured. Determine whether PIK3IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TRIM38. Does this perturbation cause a significant change in TRIM38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TRIM38. Does this perturbation cause a significant change in TRIM38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1070,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Does this perturbation cause a significant change in ADAMTS10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Does this perturbation cause a significant change in ADAMTS10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in DST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in DST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1700,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Does this perturbation cause a significant change in UBE2V1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Does this perturbation cause a significant change in UBE2V1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of RCBTB2. Does perturbing STT3A lead to a significant change in RCBTB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of RCBTB2. Does perturbing STT3A lead to a significant change in RCBTB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3950,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Does this perturbation cause a significant change in SERPINF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Does this perturbation cause a significant change in SERPINF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2700,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Does this perturbation cause a significant change in RAI14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Does this perturbation cause a significant change in RAI14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Determine whether RP11-363D14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Determine whether RP11-363D14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in UHMK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in UHMK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of DYNC1H1. Does perturbing ARHGAP22 lead to a significant change in DYNC1H1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of DYNC1H1. Does perturbing ARHGAP22 lead to a significant change in DYNC1H1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PAXBP1. Does perturbing DNAJC19 lead to a significant change in PAXBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PAXBP1. Does perturbing DNAJC19 lead to a significant change in PAXBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4610,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Does this perturbation cause a significant change in P4HB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Does this perturbation cause a significant change in P4HB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of PTGS1. Does this perturbation cause a significant change in PTGS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of PTGS1. Does this perturbation cause a significant change in PTGS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TRPM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TRPM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of NRIP1. Does perturbing BHLHE40 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of NRIP1. Does perturbing BHLHE40 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of BRWD3. Does this perturbation cause a significant change in BRWD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of BRWD3. Does this perturbation cause a significant change in BRWD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of HIST1H1D. Does this perturbation cause a significant change in HIST1H1D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of HIST1H1D. Does this perturbation cause a significant change in HIST1H1D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2223,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and GPRC5C expression is observed. Does this perturbation lead to a significant difference in GPRC5C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and GPRC5C expression is observed. Does this perturbation lead to a significant difference in GPRC5C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and AC018878.3 expression is measured. Determine whether AC018878.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and AC018878.3 expression is measured. Determine whether AC018878.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and MARCH8 expression is measured. Determine whether MARCH8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and MARCH8 expression is measured. Determine whether MARCH8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PTPRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PTPRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of STC2. Does this perturbation cause a significant change in STC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of STC2. Does this perturbation cause a significant change in STC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in AC104532.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in AC104532.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
218,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor NFE2 expression. Decide whether this perturbation leads to a significant alteration in NFE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor NFE2 expression. Decide whether this perturbation leads to a significant alteration in NFE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and GATA3 expression is quantified. Does this perturbation result in a significant change in GATA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and GATA3 expression is quantified. Does this perturbation result in a significant change in GATA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of TAP1. Does this perturbation cause a significant change in TAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of TAP1. Does this perturbation cause a significant change in TAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3870,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Does this perturbation cause a significant change in C9orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Does this perturbation cause a significant change in C9orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5083,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and GPR146 expression is observed. Does this perturbation lead to a significant difference in GPR146 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and GPR146 expression is observed. Does this perturbation lead to a significant difference in GPR146 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
22,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and RP11-573D15.9 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and RP11-573D15.9 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of PDK2. Does this perturbation cause a significant change in PDK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of PDK2. Does this perturbation cause a significant change in PDK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
583,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and MYH7B expression is observed. Does this perturbation lead to a significant difference in MYH7B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and MYH7B expression is observed. Does this perturbation lead to a significant difference in MYH7B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ANPEP. Does this perturbation cause a significant change in ANPEP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ANPEP. Does this perturbation cause a significant change in ANPEP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2228,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor GPRC5C expression. Decide whether this perturbation leads to a significant alteration in GPRC5C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor GPRC5C expression. Decide whether this perturbation leads to a significant alteration in GPRC5C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RP11-157D23.2. Does this perturbation cause a significant change in RP11-157D23.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RP11-157D23.2. Does this perturbation cause a significant change in RP11-157D23.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1210,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Does this perturbation cause a significant change in JARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Does this perturbation cause a significant change in JARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2238,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor FAM212A expression. Decide whether this perturbation leads to a significant alteration in FAM212A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor FAM212A expression. Decide whether this perturbation leads to a significant alteration in FAM212A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of IDS. Does this perturbation cause a significant change in IDS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of IDS. Does this perturbation cause a significant change in IDS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
40,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Does this perturbation cause a significant change in LPAR5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Does this perturbation cause a significant change in LPAR5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ZNF678 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ZNF678 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
990,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Does this perturbation cause a significant change in SHOX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Does this perturbation cause a significant change in SHOX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
720,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Does this perturbation cause a significant change in RP11-132A1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Does this perturbation cause a significant change in RP11-132A1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3423,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-640M9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-640M9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Determine whether CST7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Determine whether CST7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
20,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of QSER1. Does perturbing SEC61G lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of QSER1. Does perturbing SEC61G lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3680,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Does this perturbation cause a significant change in SLC27A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Does this perturbation cause a significant change in SLC27A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and SMCO1 expression is measured. Determine whether SMCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and SMCO1 expression is measured. Determine whether SMCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2058,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3230,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Does this perturbation cause a significant change in RP11-16E12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Does this perturbation cause a significant change in RP11-16E12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in COPB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in COPB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
970,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4520,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Does this perturbation cause a significant change in ATF7IP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Does this perturbation cause a significant change in ATF7IP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in IL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in IL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
90,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Does this perturbation cause a significant change in RP11-141B14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Does this perturbation cause a significant change in RP11-141B14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is measured. Determine whether RP11-38P22.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is measured. Determine whether RP11-38P22.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5093,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and TGOLN2 expression is observed. Does this perturbation lead to a significant difference in TGOLN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and TGOLN2 expression is observed. Does this perturbation lead to a significant difference in TGOLN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of DSC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of DSC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
708,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor UQCRB expression. Decide whether this perturbation leads to a significant alteration in UQCRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor UQCRB expression. Decide whether this perturbation leads to a significant alteration in UQCRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1463,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of SLC25A35. Does this perturbation cause a significant change in SLC25A35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of SLC25A35. Does this perturbation cause a significant change in SLC25A35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in RP11-254F7.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in RP11-254F7.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5140,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Does this perturbation cause a significant change in RAD51AP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Does this perturbation cause a significant change in RAD51AP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Determine whether CTC-308K20.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Determine whether CTC-308K20.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CMTM6 expression is measured. Determine whether CMTM6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CMTM6 expression is measured. Determine whether CMTM6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2953,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ATP5EP2 expression is observed. Does this perturbation lead to a significant difference in ATP5EP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ATP5EP2 expression is observed. Does this perturbation lead to a significant difference in ATP5EP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC008074.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC008074.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in CTSF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in CTSF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
610,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Does this perturbation cause a significant change in HP1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Does this perturbation cause a significant change in HP1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of DKFZP779L1853. Does this perturbation cause a significant change in DKFZP779L1853 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of DKFZP779L1853. Does this perturbation cause a significant change in DKFZP779L1853 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of IDS is measured. Determine whether IDS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of IDS is measured. Determine whether IDS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4160,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Does this perturbation cause a significant change in SSBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Does this perturbation cause a significant change in SSBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Determine whether WHSC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Determine whether WHSC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
230,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Does this perturbation cause a significant change in PTPRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Does this perturbation cause a significant change in PTPRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2268,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor C6orf120 expression. Decide whether this perturbation leads to a significant alteration in C6orf120 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor C6orf120 expression. Decide whether this perturbation leads to a significant alteration in C6orf120 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1570,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and NBEAL2 expression is measured. Determine whether NBEAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and NBEAL2 expression is measured. Determine whether NBEAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
950,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Does this perturbation cause a significant change in HERC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Does this perturbation cause a significant change in HERC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Determine whether NOXA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Determine whether NOXA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Determine whether VAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Determine whether VAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in TLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in TLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2288,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1543,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and CTD-2267D19.3 expression is observed. Does this perturbation lead to a significant difference in CTD-2267D19.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and CTD-2267D19.3 expression is observed. Does this perturbation lead to a significant difference in CTD-2267D19.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Determine whether PLB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Determine whether PLB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and LRIF1 expression is measured. Determine whether LRIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and LRIF1 expression is measured. Determine whether LRIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Determine whether KIAA1586 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Determine whether KIAA1586 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of HM13. Does this perturbation cause a significant change in HM13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of HM13. Does this perturbation cause a significant change in HM13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of KIF4A. Does this perturbation cause a significant change in KIF4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of KIF4A. Does this perturbation cause a significant change in KIF4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
67,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RIOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RIOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5008,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1290,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Does this perturbation cause a significant change in RP11-573D15.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Does this perturbation cause a significant change in RP11-573D15.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of TSC22D4. Does perturbing HSPA5 lead to a significant change in TSC22D4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of TSC22D4. Does perturbing HSPA5 lead to a significant change in TSC22D4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2660,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Does this perturbation cause a significant change in ASPM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Does this perturbation cause a significant change in ASPM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in GATA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in GATA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4793,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ANPEP expression is observed. Does this perturbation lead to a significant difference in ANPEP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ANPEP expression is observed. Does this perturbation lead to a significant difference in ANPEP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in LINC01031 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in LINC01031 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of DOCK8. Does perturbing PDIA6 lead to a significant change in DOCK8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of DOCK8. Does perturbing PDIA6 lead to a significant change in DOCK8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ARHGAP30 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ARHGAP30 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of IL8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of IL8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Determine whether RP11-838N2.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Determine whether RP11-838N2.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of TTC18. Does this perturbation cause a significant change in TTC18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of TTC18. Does this perturbation cause a significant change in TTC18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of MORC2-AS1. Does this perturbation cause a significant change in MORC2-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of MORC2-AS1. Does this perturbation cause a significant change in MORC2-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and OR2T6 expression is measured. Determine whether OR2T6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and OR2T6 expression is measured. Determine whether OR2T6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3750,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Does this perturbation cause a significant change in KIAA1432 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Does this perturbation cause a significant change in KIAA1432 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SLBP expression is quantified. Does this perturbation result in a significant change in SLBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SLBP expression is quantified. Does this perturbation result in a significant change in SLBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RNF8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RNF8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4150,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Does this perturbation cause a significant change in PDRG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Does this perturbation cause a significant change in PDRG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3253,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TRIM38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TRIM38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Determine whether SSBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Determine whether SSBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is measured. Determine whether RP1-274L7.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is measured. Determine whether RP1-274L7.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of LTB. Does perturbing SEC61A1 lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of LTB. Does perturbing SEC61A1 lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ZNF429 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ZNF429 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of HAGH. Does perturbing SEC63 lead to a significant change in HAGH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of HAGH. Does perturbing SEC63 lead to a significant change in HAGH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and STK17B expression is measured. Determine whether STK17B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and STK17B expression is measured. Determine whether STK17B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in APOL4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in APOL4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of SERPING1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of SERPING1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Determine whether DSC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Determine whether DSC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDK13 expression is measured. Determine whether CDK13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDK13 expression is measured. Determine whether CDK13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ZP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ZP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2713,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3380,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Does this perturbation cause a significant change in TRIM38 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Does this perturbation cause a significant change in TRIM38 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in THBS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in THBS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SP100. Does this perturbation cause a significant change in SP100 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SP100. Does this perturbation cause a significant change in SP100 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and SHOX2 expression is quantified. Does this perturbation result in a significant change in SHOX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and SHOX2 expression is quantified. Does this perturbation result in a significant change in SHOX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-227G15.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-227G15.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of LIMS1. Does this perturbation cause a significant change in LIMS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of LIMS1. Does this perturbation cause a significant change in LIMS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of PLA2G15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of PLA2G15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Determine whether SAMM50 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Determine whether SAMM50 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PSMC1 expression is quantified. Does this perturbation result in a significant change in PSMC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PSMC1 expression is quantified. Does this perturbation result in a significant change in PSMC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4280,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CTC-550B14.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CTC-550B14.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3588,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP3-465N24.6 expression. Decide whether this perturbation leads to a significant alteration in RP3-465N24.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP3-465N24.6 expression. Decide whether this perturbation leads to a significant alteration in RP3-465N24.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2428,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4110,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Does this perturbation cause a significant change in CDCA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Does this perturbation cause a significant change in CDCA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4848,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EPS15 expression. Decide whether this perturbation leads to a significant alteration in EPS15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EPS15 expression. Decide whether this perturbation leads to a significant alteration in EPS15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4823,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
213,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and NFE2 expression is observed. Does this perturbation lead to a significant difference in NFE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and NFE2 expression is observed. Does this perturbation lead to a significant difference in NFE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3210,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Does this perturbation cause a significant change in TTC32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Does this perturbation cause a significant change in TTC32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and SLC26A1 expression is measured. Determine whether SLC26A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and SLC26A1 expression is measured. Determine whether SLC26A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of C17orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of C17orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in CASP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in CASP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in HPCAL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in HPCAL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Determine whether ARHGAP11A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Determine whether ARHGAP11A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of AC015987.2. Does this perturbation cause a significant change in AC015987.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of AC015987.2. Does this perturbation cause a significant change in AC015987.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PIK3IP1 expression is quantified. Does this perturbation result in a significant change in PIK3IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PIK3IP1 expression is quantified. Does this perturbation result in a significant change in PIK3IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3703,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and PARP11 expression is observed. Does this perturbation lead to a significant difference in PARP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and PARP11 expression is observed. Does this perturbation lead to a significant difference in PARP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of KIAA1731. Does perturbing CARS lead to a significant change in KIAA1731 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of KIAA1731. Does perturbing CARS lead to a significant change in KIAA1731 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ITGB2. Does this perturbation cause a significant change in ITGB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ITGB2. Does this perturbation cause a significant change in ITGB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2290,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Does this perturbation cause a significant change in KLF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Does this perturbation cause a significant change in KLF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
528,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor DDX6 expression. Decide whether this perturbation leads to a significant alteration in DDX6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor DDX6 expression. Decide whether this perturbation leads to a significant alteration in DDX6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2380,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Does this perturbation cause a significant change in DKFZP779L1853 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Does this perturbation cause a significant change in DKFZP779L1853 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ERV3-1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ERV3-1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3850,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Does this perturbation cause a significant change in PHF21A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Does this perturbation cause a significant change in PHF21A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA0922 expression is quantified. Does this perturbation result in a significant change in KIAA0922 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA0922 expression is quantified. Does this perturbation result in a significant change in KIAA0922 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CCDC69 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CCDC69 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-789C1.1. Does this perturbation cause a significant change in RP11-789C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-789C1.1. Does this perturbation cause a significant change in RP11-789C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and SERPINF2 expression is measured. Determine whether SERPINF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and SERPINF2 expression is measured. Determine whether SERPINF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of THBS1. Does this perturbation cause a significant change in THBS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of THBS1. Does this perturbation cause a significant change in THBS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and DDX3X expression is quantified. Does this perturbation result in a significant change in DDX3X expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and DDX3X expression is quantified. Does this perturbation result in a significant change in DDX3X expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of POU2F2. Does this perturbation cause a significant change in POU2F2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of POU2F2. Does this perturbation cause a significant change in POU2F2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ROBO1 expression is quantified. Does this perturbation result in a significant change in ROBO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ROBO1 expression is quantified. Does this perturbation result in a significant change in ROBO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of HAGH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of HAGH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5150,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Does this perturbation cause a significant change in ROCK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Does this perturbation cause a significant change in ROCK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5103,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and PIK3R1 expression is observed. Does this perturbation lead to a significant difference in PIK3R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and PIK3R1 expression is observed. Does this perturbation lead to a significant difference in PIK3R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AC015987.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AC015987.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Determine whether MYH7B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Determine whether MYH7B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of WARS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of WARS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2150,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Does this perturbation cause a significant change in SNRNP25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Does this perturbation cause a significant change in SNRNP25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of C9orf64. Does this perturbation cause a significant change in C9orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of C9orf64. Does this perturbation cause a significant change in C9orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA0922. Does this perturbation cause a significant change in KIAA0922 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA0922. Does this perturbation cause a significant change in KIAA0922 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ATF7IP2. Does perturbing DHDDS lead to a significant change in ATF7IP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ATF7IP2. Does perturbing DHDDS lead to a significant change in ATF7IP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4063,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and CENPF expression is observed. Does this perturbation lead to a significant difference in CENPF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and CENPF expression is observed. Does this perturbation lead to a significant difference in CENPF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1628,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ATP6AP2 expression. Decide whether this perturbation leads to a significant alteration in ATP6AP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ATP6AP2 expression. Decide whether this perturbation leads to a significant alteration in ATP6AP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and KLF6 expression is measured. Determine whether KLF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and KLF6 expression is measured. Determine whether KLF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of SLC26A1. Does this perturbation cause a significant change in SLC26A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of SLC26A1. Does this perturbation cause a significant change in SLC26A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of DSC2. Does perturbing UFM1 lead to a significant change in DSC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of DSC2. Does perturbing UFM1 lead to a significant change in DSC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2278,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor PSORS1C1 expression. Decide whether this perturbation leads to a significant alteration in PSORS1C1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor PSORS1C1 expression. Decide whether this perturbation leads to a significant alteration in PSORS1C1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3980,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of S100A13. Does perturbing HSD17B12 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of S100A13. Does perturbing HSD17B12 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and HIST1H1D expression is measured. Determine whether HIST1H1D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and HIST1H1D expression is measured. Determine whether HIST1H1D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
810,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Does this perturbation cause a significant change in DNTTIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Does this perturbation cause a significant change in DNTTIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and GPRC5C expression is measured. Determine whether GPRC5C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and GPRC5C expression is measured. Determine whether GPRC5C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of AC015987.2. Does perturbing GNPNAT1 lead to a significant change in AC015987.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of AC015987.2. Does perturbing GNPNAT1 lead to a significant change in AC015987.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TET1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TET1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TUBA1C. Does this perturbation cause a significant change in TUBA1C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TUBA1C. Does this perturbation cause a significant change in TUBA1C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Determine whether C9orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Determine whether C9orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of IDS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of IDS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of UFD1L. Does this perturbation cause a significant change in UFD1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of UFD1L. Does this perturbation cause a significant change in UFD1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EXOC3L2. Does this perturbation cause a significant change in EXOC3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EXOC3L2. Does this perturbation cause a significant change in EXOC3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1838,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ATP2A3 expression. Decide whether this perturbation leads to a significant alteration in ATP2A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ATP2A3 expression. Decide whether this perturbation leads to a significant alteration in ATP2A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3450,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Does this perturbation cause a significant change in ZFP36L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Does this perturbation cause a significant change in ZFP36L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of MBNL1. Does perturbing XRN1 lead to a significant change in MBNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of MBNL1. Does perturbing XRN1 lead to a significant change in MBNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4333,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and GRN expression is observed. Does this perturbation lead to a significant difference in GRN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and GRN expression is observed. Does this perturbation lead to a significant difference in GRN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1690,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2168,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor PDK2 expression. Decide whether this perturbation leads to a significant alteration in PDK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor PDK2 expression. Decide whether this perturbation leads to a significant alteration in PDK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of SPCS2. Does perturbing SLMO2 lead to a significant change in SPCS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of SPCS2. Does perturbing SLMO2 lead to a significant change in SPCS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4138,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor WDR72 expression. Decide whether this perturbation leads to a significant alteration in WDR72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor WDR72 expression. Decide whether this perturbation leads to a significant alteration in WDR72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PIF1. Does this perturbation cause a significant change in PIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PIF1. Does this perturbation cause a significant change in PIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HRK. Does perturbing IARS2 lead to a significant change in HRK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HRK. Does perturbing IARS2 lead to a significant change in HRK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ATP6AP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ATP6AP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3190,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Does this perturbation cause a significant change in TRIM24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Does this perturbation cause a significant change in TRIM24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FYTTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FYTTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP3-465N24.6. Does this perturbation cause a significant change in RP3-465N24.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP3-465N24.6. Does this perturbation cause a significant change in RP3-465N24.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of FCGRT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of FCGRT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Determine whether PITPNB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Determine whether PITPNB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Determine whether PTPN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Determine whether PTPN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of RP11-38P22.2. Does perturbing IARS2 lead to a significant change in RP11-38P22.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of RP11-38P22.2. Does perturbing IARS2 lead to a significant change in RP11-38P22.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ERV3-1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ERV3-1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NPDC1 expression is measured. Determine whether NPDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NPDC1 expression is measured. Determine whether NPDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of PPP4R2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of PPP4R2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and MEX3B expression is measured. Determine whether MEX3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and MEX3B expression is measured. Determine whether MEX3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of CRYM. Does perturbing MARS lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of CRYM. Does perturbing MARS lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of KCNJ13. Does perturbing EIF2S1 lead to a significant change in KCNJ13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of KCNJ13. Does perturbing EIF2S1 lead to a significant change in KCNJ13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1000,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Does this perturbation cause a significant change in RP11-334C17.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Does this perturbation cause a significant change in RP11-334C17.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PTPN11 expression is measured. Determine whether PTPN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PTPN11 expression is measured. Determine whether PTPN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of TTC18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of TTC18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of APOL4. Does this perturbation cause a significant change in APOL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of APOL4. Does this perturbation cause a significant change in APOL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4688,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in LINC00862 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in LINC00862 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3693,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and TTC18 expression is observed. Does this perturbation lead to a significant difference in TTC18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and TTC18 expression is observed. Does this perturbation lead to a significant difference in TTC18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Determine whether DDX6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Determine whether DDX6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of LIMS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of LIMS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
65,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RIOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RIOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2553,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and MORC2-AS1 expression is observed. Does this perturbation lead to a significant difference in MORC2-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and MORC2-AS1 expression is observed. Does this perturbation lead to a significant difference in MORC2-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in LRRC4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in LRRC4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SLBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SLBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2373,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and PPP4R2 expression is observed. Does this perturbation lead to a significant difference in PPP4R2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and PPP4R2 expression is observed. Does this perturbation lead to a significant difference in PPP4R2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ANXA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ANXA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2473,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and MORC2-AS1 expression is measured. Determine whether MORC2-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and MORC2-AS1 expression is measured. Determine whether MORC2-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of NRIP1. Does perturbing EIF2S1 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of NRIP1. Does perturbing EIF2S1 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is quantified. Does this perturbation result in a significant change in RP11-3D4.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is quantified. Does this perturbation result in a significant change in RP11-3D4.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and ATP2A3 expression is measured. Determine whether ATP2A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and ATP2A3 expression is measured. Determine whether ATP2A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
550,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Does this perturbation cause a significant change in OPTN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Does this perturbation cause a significant change in OPTN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4443,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CTBS expression is observed. Does this perturbation lead to a significant difference in CTBS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CTBS expression is observed. Does this perturbation lead to a significant difference in CTBS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CLINT1 expression is quantified. Does this perturbation result in a significant change in CLINT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CLINT1 expression is quantified. Does this perturbation result in a significant change in CLINT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of NTRK1. Does perturbing CCND3 lead to a significant change in NTRK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of NTRK1. Does perturbing CCND3 lead to a significant change in NTRK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of GATA2. Does this perturbation cause a significant change in GATA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of GATA2. Does this perturbation cause a significant change in GATA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Determine whether CCDC69 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Determine whether CCDC69 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of PLB1. Does this perturbation cause a significant change in PLB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of PLB1. Does this perturbation cause a significant change in PLB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4158,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor PDRG1 expression. Decide whether this perturbation leads to a significant alteration in PDRG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor PDRG1 expression. Decide whether this perturbation leads to a significant alteration in PDRG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4190,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of TAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of TAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of NAV2. Does this perturbation cause a significant change in NAV2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of NAV2. Does this perturbation cause a significant change in NAV2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ANKRD11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ANKRD11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
313,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1658,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor EBI3 expression. Decide whether this perturbation leads to a significant alteration in EBI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor EBI3 expression. Decide whether this perturbation leads to a significant alteration in EBI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of EP400. Does this perturbation cause a significant change in EP400 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of EP400. Does this perturbation cause a significant change in EP400 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PDE4D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PDE4D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of SLFNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of SLFNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Determine whether KCTD19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Determine whether KCTD19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RP11-360L9.8. Does perturbing AARS lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RP11-360L9.8. Does perturbing AARS lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and WHSC1 expression is measured. Determine whether WHSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and WHSC1 expression is measured. Determine whether WHSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5063,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of FCGR2A. Does perturbing TTI2 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of FCGR2A. Does perturbing TTI2 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
888,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor GATA3 expression. Decide whether this perturbation leads to a significant alteration in GATA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor GATA3 expression. Decide whether this perturbation leads to a significant alteration in GATA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is measured. Determine whether CTD-2001C12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is measured. Determine whether CTD-2001C12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and C17orf64 expression is quantified. Does this perturbation result in a significant change in C17orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and C17orf64 expression is quantified. Does this perturbation result in a significant change in C17orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Determine whether PIK3IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Determine whether PIK3IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and PARP11 expression is quantified. Does this perturbation result in a significant change in PARP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and PARP11 expression is quantified. Does this perturbation result in a significant change in PARP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Determine whether WHAMM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Determine whether WHAMM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MT2A. Does this perturbation cause a significant change in MT2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MT2A. Does this perturbation cause a significant change in MT2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2000,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Does this perturbation cause a significant change in C1GALT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Does this perturbation cause a significant change in C1GALT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of HLA-E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of HLA-E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of SPEN. Does perturbing PDIA6 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of SPEN. Does perturbing PDIA6 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
88,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor PHF3 expression. Decide whether this perturbation leads to a significant alteration in PHF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor PHF3 expression. Decide whether this perturbation leads to a significant alteration in PHF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2913,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AFF1 expression is observed. Does this perturbation lead to a significant difference in AFF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AFF1 expression is observed. Does this perturbation lead to a significant difference in AFF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3500,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and WDR3 expression is measured. Determine whether WDR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and WDR3 expression is measured. Determine whether WDR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Determine whether ZMYND8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Determine whether ZMYND8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Determine whether SHOX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Determine whether SHOX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3968,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4200,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and IL8 expression is quantified. Does this perturbation result in a significant change in IL8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and IL8 expression is quantified. Does this perturbation result in a significant change in IL8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in HLTF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in HLTF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of PKDCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of PKDCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of LRRC4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of LRRC4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of GRN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of GRN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and GMEB1 expression is quantified. Does this perturbation result in a significant change in GMEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and GMEB1 expression is quantified. Does this perturbation result in a significant change in GMEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of S100A10. Does perturbing CARS lead to a significant change in S100A10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of S100A10. Does perturbing CARS lead to a significant change in S100A10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and USP37 expression is quantified. Does this perturbation result in a significant change in USP37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and USP37 expression is quantified. Does this perturbation result in a significant change in USP37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CTCFL expression is quantified. Does this perturbation result in a significant change in CTCFL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CTCFL expression is quantified. Does this perturbation result in a significant change in CTCFL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ITGB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ITGB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Determine whether LINC00657 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Determine whether LINC00657 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and GATA3 expression is measured. Determine whether GATA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and GATA3 expression is measured. Determine whether GATA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4180,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Does this perturbation cause a significant change in ANKRD33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Does this perturbation cause a significant change in ANKRD33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of LINC00657. Does perturbing OST4 lead to a significant change in LINC00657 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of LINC00657. Does perturbing OST4 lead to a significant change in LINC00657 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2113,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of RP11-434H6.6. Does this perturbation cause a significant change in RP11-434H6.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of RP11-434H6.6. Does this perturbation cause a significant change in RP11-434H6.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SLBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SLBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2493,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and CD58 expression is observed. Does this perturbation lead to a significant difference in CD58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and CD58 expression is observed. Does this perturbation lead to a significant difference in CD58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of RP11-390B4.5. Does this perturbation cause a significant change in RP11-390B4.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of RP11-390B4.5. Does this perturbation cause a significant change in RP11-390B4.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of NFAT5. Does perturbing GMPPB lead to a significant change in NFAT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of NFAT5. Does perturbing GMPPB lead to a significant change in NFAT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ATF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ATF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of C1GALT1. Does this perturbation cause a significant change in C1GALT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of C1GALT1. Does this perturbation cause a significant change in C1GALT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of NOX5. Does this perturbation cause a significant change in NOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of NOX5. Does this perturbation cause a significant change in NOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and GATA2 expression is measured. Determine whether GATA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and GATA2 expression is measured. Determine whether GATA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in ACRV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in ACRV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of TSNAXIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of TSNAXIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is quantified. Does this perturbation result in a significant change in RP11-38P22.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is quantified. Does this perturbation result in a significant change in RP11-38P22.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and C19orf59 expression is measured. Determine whether C19orf59 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and C19orf59 expression is measured. Determine whether C19orf59 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2160,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Does this perturbation cause a significant change in PDK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Does this perturbation cause a significant change in PDK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3288,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor AC018878.3 expression. Decide whether this perturbation leads to a significant alteration in AC018878.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor AC018878.3 expression. Decide whether this perturbation leads to a significant alteration in AC018878.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of GNPTG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of GNPTG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Determine whether LINC00938 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Determine whether LINC00938 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of FYTTD1. Does this perturbation cause a significant change in FYTTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of FYTTD1. Does this perturbation cause a significant change in FYTTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of RP11-390B4.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of RP11-390B4.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of SNHG10. Does perturbing QARS lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of SNHG10. Does perturbing QARS lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of PBDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of PBDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of RP11-212I21.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of RP11-212I21.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
448,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in DNMBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in DNMBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Determine whether STC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Determine whether STC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in RPL39 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in RPL39 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
548,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ITGB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ITGB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2868,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PIK3IP1 expression. Decide whether this perturbation leads to a significant alteration in PIK3IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PIK3IP1 expression. Decide whether this perturbation leads to a significant alteration in PIK3IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
183,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and STC2 expression is observed. Does this perturbation lead to a significant difference in STC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and STC2 expression is observed. Does this perturbation lead to a significant difference in STC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4680,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
123,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3998,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor RP11-242O24.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-242O24.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor RP11-242O24.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-242O24.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2483,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and HLTF expression is observed. Does this perturbation lead to a significant difference in HLTF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and HLTF expression is observed. Does this perturbation lead to a significant difference in HLTF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1273,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5158,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ROCK1 expression. Decide whether this perturbation leads to a significant alteration in ROCK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ROCK1 expression. Decide whether this perturbation leads to a significant alteration in ROCK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AC007038.7. Does perturbing TARS lead to a significant change in AC007038.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AC007038.7. Does perturbing TARS lead to a significant change in AC007038.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP13-216E22.4. Does this perturbation cause a significant change in RP13-216E22.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP13-216E22.4. Does this perturbation cause a significant change in RP13-216E22.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3243,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and SERPING1 expression is observed. Does this perturbation lead to a significant difference in SERPING1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and SERPING1 expression is observed. Does this perturbation lead to a significant difference in SERPING1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ANKRD33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ANKRD33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of MEX3B. Does this perturbation cause a significant change in MEX3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of MEX3B. Does this perturbation cause a significant change in MEX3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3678,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ZC3H7A expression. Decide whether this perturbation leads to a significant alteration in ZC3H7A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ZC3H7A expression. Decide whether this perturbation leads to a significant alteration in ZC3H7A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1208,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor GMEB1 expression. Decide whether this perturbation leads to a significant alteration in GMEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor GMEB1 expression. Decide whether this perturbation leads to a significant alteration in GMEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3488,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor PTGS1 expression. Decide whether this perturbation leads to a significant alteration in PTGS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor PTGS1 expression. Decide whether this perturbation leads to a significant alteration in PTGS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of SPEN. Does perturbing UFM1 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of SPEN. Does perturbing UFM1 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and NAV2 expression is quantified. Does this perturbation result in a significant change in NAV2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and NAV2 expression is quantified. Does this perturbation result in a significant change in NAV2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Determine whether TAGLN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Determine whether TAGLN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ZNF341 expression is quantified. Does this perturbation result in a significant change in ZNF341 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ZNF341 expression is quantified. Does this perturbation result in a significant change in ZNF341 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1163,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and KDM1B expression is observed. Does this perturbation lead to a significant difference in KDM1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and KDM1B expression is observed. Does this perturbation lead to a significant difference in KDM1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and DSC2 expression is measured. Determine whether DSC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and DSC2 expression is measured. Determine whether DSC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HIST1H3D. Does this perturbation cause a significant change in HIST1H3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HIST1H3D. Does this perturbation cause a significant change in HIST1H3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TTC32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TTC32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3733,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and PITPNB expression is observed. Does this perturbation lead to a significant difference in PITPNB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and PITPNB expression is observed. Does this perturbation lead to a significant difference in PITPNB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2143,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and NINJ2 expression is observed. Does this perturbation lead to a significant difference in NINJ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and NINJ2 expression is observed. Does this perturbation lead to a significant difference in NINJ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ESCO1 expression is measured. Determine whether ESCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ESCO1 expression is measured. Determine whether ESCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in RP11-471M2.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in RP11-471M2.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is measured. Determine whether RP11-328J2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is measured. Determine whether RP11-328J2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ARHGAP11A. Does perturbing PTDSS1 lead to a significant change in ARHGAP11A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ARHGAP11A. Does perturbing PTDSS1 lead to a significant change in ARHGAP11A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3470,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Does this perturbation cause a significant change in BACH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Does this perturbation cause a significant change in BACH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of NFE2. Does this perturbation cause a significant change in NFE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of NFE2. Does this perturbation cause a significant change in NFE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of IL13RA1. Does this perturbation cause a significant change in IL13RA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of IL13RA1. Does this perturbation cause a significant change in IL13RA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of SSBP2. Does this perturbation cause a significant change in SSBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of SSBP2. Does this perturbation cause a significant change in SSBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1043,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HRK expression is observed. Does this perturbation lead to a significant difference in HRK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HRK expression is observed. Does this perturbation lead to a significant difference in HRK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4488,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1390,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Does this perturbation cause a significant change in NUF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Does this perturbation cause a significant change in NUF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Determine whether CPQ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Determine whether CPQ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of MEX3B. Does perturbing SLMO2 lead to a significant change in MEX3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of MEX3B. Does perturbing SLMO2 lead to a significant change in MEX3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1928,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor AKAP11 expression. Decide whether this perturbation leads to a significant alteration in AKAP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor AKAP11 expression. Decide whether this perturbation leads to a significant alteration in AKAP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
293,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ATP11B expression is observed. Does this perturbation lead to a significant difference in ATP11B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ATP11B expression is observed. Does this perturbation lead to a significant difference in ATP11B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PTPN11. Does this perturbation cause a significant change in PTPN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PTPN11. Does this perturbation cause a significant change in PTPN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3558,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor CCRL2 expression. Decide whether this perturbation leads to a significant alteration in CCRL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor CCRL2 expression. Decide whether this perturbation leads to a significant alteration in CCRL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of KCTD19. Does perturbing MANF lead to a significant change in KCTD19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of KCTD19. Does perturbing MANF lead to a significant change in KCTD19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is quantified. Does this perturbation result in a significant change in C1GALT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is quantified. Does this perturbation result in a significant change in C1GALT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CHD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CHD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of NUFIP2. Does this perturbation cause a significant change in NUFIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of NUFIP2. Does this perturbation cause a significant change in NUFIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4968,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor EIF4B expression. Decide whether this perturbation leads to a significant alteration in EIF4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor EIF4B expression. Decide whether this perturbation leads to a significant alteration in EIF4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NOXA1. Does this perturbation cause a significant change in NOXA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NOXA1. Does this perturbation cause a significant change in NOXA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and PIK3R1 expression is measured. Determine whether PIK3R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and PIK3R1 expression is measured. Determine whether PIK3R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in SLC26A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in SLC26A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ANKRD33 expression is quantified. Does this perturbation result in a significant change in ANKRD33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ANKRD33 expression is quantified. Does this perturbation result in a significant change in ANKRD33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of STK17B. Does perturbing XRN1 lead to a significant change in STK17B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of STK17B. Does perturbing XRN1 lead to a significant change in STK17B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3718,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor C17orf64 expression. Decide whether this perturbation leads to a significant alteration in C17orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor C17orf64 expression. Decide whether this perturbation leads to a significant alteration in C17orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Determine whether C10orf32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Determine whether C10orf32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
203,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and KLK1 expression is observed. Does this perturbation lead to a significant difference in KLK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and KLK1 expression is observed. Does this perturbation lead to a significant difference in KLK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SIGLEC6 expression is quantified. Does this perturbation result in a significant change in SIGLEC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SIGLEC6 expression is quantified. Does this perturbation result in a significant change in SIGLEC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and GNPTG expression is measured. Determine whether GNPTG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and GNPTG expression is measured. Determine whether GNPTG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of WHAMM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of WHAMM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of GATA2. Does perturbing SPCS2 lead to a significant change in GATA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of GATA2. Does perturbing SPCS2 lead to a significant change in GATA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4993,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ZCCHC11 expression is observed. Does this perturbation lead to a significant difference in ZCCHC11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ZCCHC11 expression is observed. Does this perturbation lead to a significant difference in ZCCHC11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and C12orf44 expression is quantified. Does this perturbation result in a significant change in C12orf44 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and C12orf44 expression is quantified. Does this perturbation result in a significant change in C12orf44 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
110,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Does this perturbation cause a significant change in RP11-65L19.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Does this perturbation cause a significant change in RP11-65L19.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4543,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2273,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and PSORS1C1 expression is observed. Does this perturbation lead to a significant difference in PSORS1C1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and PSORS1C1 expression is observed. Does this perturbation lead to a significant difference in PSORS1C1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Determine whether NINJ2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Determine whether NINJ2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of VIM-AS1. Does perturbing SYVN1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of VIM-AS1. Does perturbing SYVN1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CTC-550B14.7. Does this perturbation cause a significant change in CTC-550B14.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CTC-550B14.7. Does this perturbation cause a significant change in CTC-550B14.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of GATA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of GATA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CMTM6 expression is quantified. Does this perturbation result in a significant change in CMTM6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CMTM6 expression is quantified. Does this perturbation result in a significant change in CMTM6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
813,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and DNTTIP2 expression is observed. Does this perturbation lead to a significant difference in DNTTIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and DNTTIP2 expression is observed. Does this perturbation lead to a significant difference in DNTTIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3433,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP5 expression is observed. Does this perturbation lead to a significant difference in ARHGAP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP5 expression is observed. Does this perturbation lead to a significant difference in ARHGAP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ERP29 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ERP29 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IFT27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IFT27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and PTGS1 expression is quantified. Does this perturbation result in a significant change in PTGS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and PTGS1 expression is quantified. Does this perturbation result in a significant change in PTGS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of UBE3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of UBE3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in SLC25A35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in SLC25A35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
428,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CD9 expression. Decide whether this perturbation leads to a significant alteration in CD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CD9 expression. Decide whether this perturbation leads to a significant alteration in CD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1350,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Does this perturbation cause a significant change in TAGLN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Does this perturbation cause a significant change in TAGLN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of RP11-334C17.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of RP11-334C17.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NUF2 expression is quantified. Does this perturbation result in a significant change in NUF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NUF2 expression is quantified. Does this perturbation result in a significant change in NUF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is quantified. Does this perturbation result in a significant change in SLC25A35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is quantified. Does this perturbation result in a significant change in SLC25A35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in VAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in VAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ACRV1 expression is measured. Determine whether ACRV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ACRV1 expression is measured. Determine whether ACRV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Determine whether KDM1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Determine whether KDM1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of CELF6. Does perturbing P4HB lead to a significant change in CELF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of CELF6. Does perturbing P4HB lead to a significant change in CELF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4768,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
910,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Does this perturbation cause a significant change in HIST1H3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Does this perturbation cause a significant change in HIST1H3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2300,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PDE4D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PDE4D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1240,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
340,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Does this perturbation cause a significant change in MS4A6E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Does this perturbation cause a significant change in MS4A6E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in MBNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in MBNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HERC2. Does perturbing DARS lead to a significant change in HERC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HERC2. Does perturbing DARS lead to a significant change in HERC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-328J2.1. Does perturbing SOCS1 lead to a significant change in RP11-328J2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-328J2.1. Does perturbing SOCS1 lead to a significant change in RP11-328J2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2693,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CD83 expression is observed. Does this perturbation lead to a significant difference in CD83 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CD83 expression is observed. Does this perturbation lead to a significant difference in CD83 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3938,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ZXDA expression. Decide whether this perturbation leads to a significant alteration in ZXDA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ZXDA expression. Decide whether this perturbation leads to a significant alteration in ZXDA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1020,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Does this perturbation cause a significant change in HIST1H1E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Does this perturbation cause a significant change in HIST1H1E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
848,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of NOSTRIN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of NOSTRIN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AC015987.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AC015987.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and AP000688.8 expression is measured. Determine whether AP000688.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and AP000688.8 expression is measured. Determine whether AP000688.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3508,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4950,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Does this perturbation cause a significant change in PLB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Does this perturbation cause a significant change in PLB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RIMS3 expression is quantified. Does this perturbation result in a significant change in RIMS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RIMS3 expression is quantified. Does this perturbation result in a significant change in RIMS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in KIF4A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in KIF4A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2890,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of GATA3. Does this perturbation cause a significant change in GATA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of GATA3. Does this perturbation cause a significant change in GATA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and CASP8 expression is quantified. Does this perturbation result in a significant change in CASP8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and CASP8 expression is quantified. Does this perturbation result in a significant change in CASP8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Determine whether KCTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Determine whether KCTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
16,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in RP11-322J23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in RP11-322J23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PIF1 expression is quantified. Does this perturbation result in a significant change in PIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PIF1 expression is quantified. Does this perturbation result in a significant change in PIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
170,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Does this perturbation cause a significant change in TKTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Does this perturbation cause a significant change in TKTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
388,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and FYTTD1 expression is measured. Determine whether FYTTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and FYTTD1 expression is measured. Determine whether FYTTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PDE9A expression is quantified. Does this perturbation result in a significant change in PDE9A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PDE9A expression is quantified. Does this perturbation result in a significant change in PDE9A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CST7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CST7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of PTBP3. Does perturbing SLMO2 lead to a significant change in PTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of PTBP3. Does perturbing SLMO2 lead to a significant change in PTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4420,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Does this perturbation cause a significant change in RP11-157D23.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Does this perturbation cause a significant change in RP11-157D23.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Determine whether ACE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Determine whether ACE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CCDC69. Does perturbing KCTD16 lead to a significant change in CCDC69 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CCDC69. Does perturbing KCTD16 lead to a significant change in CCDC69 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in RNF19A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in RNF19A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of CCRL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of CCRL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CD83 expression is measured. Determine whether CD83 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CD83 expression is measured. Determine whether CD83 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HIST1H1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HIST1H1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3043,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and C10orf32 expression is observed. Does this perturbation lead to a significant difference in C10orf32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and C10orf32 expression is observed. Does this perturbation lead to a significant difference in C10orf32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
753,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and TSNAXIP1 expression is observed. Does this perturbation lead to a significant difference in TSNAXIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and TSNAXIP1 expression is observed. Does this perturbation lead to a significant difference in TSNAXIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3653,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and KCNJ13 expression is observed. Does this perturbation lead to a significant difference in KCNJ13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and KCNJ13 expression is observed. Does this perturbation lead to a significant difference in KCNJ13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2088,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor PGM3 expression. Decide whether this perturbation leads to a significant alteration in PGM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor PGM3 expression. Decide whether this perturbation leads to a significant alteration in PGM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Determine whether ACRV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Determine whether ACRV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDK13. Does perturbing HSD17B12 lead to a significant change in CDK13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDK13. Does perturbing HSD17B12 lead to a significant change in CDK13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2593,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and RP11-471M2.3 expression is observed. Does this perturbation lead to a significant difference in RP11-471M2.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and RP11-471M2.3 expression is observed. Does this perturbation lead to a significant difference in RP11-471M2.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4553,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CTC-550B14.7 expression is observed. Does this perturbation lead to a significant difference in CTC-550B14.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CTC-550B14.7 expression is observed. Does this perturbation lead to a significant difference in CTC-550B14.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of LINC00938 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of LINC00938 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1970,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Does this perturbation cause a significant change in CRNDE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Does this perturbation cause a significant change in CRNDE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SETD5-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SETD5-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1393,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NUF2 expression is observed. Does this perturbation lead to a significant difference in NUF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NUF2 expression is observed. Does this perturbation lead to a significant difference in NUF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NOXA1 expression is measured. Determine whether NOXA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NOXA1 expression is measured. Determine whether NOXA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3130,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Determine whether RP11-328J2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Determine whether RP11-328J2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of RP11-132A1.4. Does perturbing DAD1 lead to a significant change in RP11-132A1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of RP11-132A1.4. Does perturbing DAD1 lead to a significant change in RP11-132A1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is quantified. Does this perturbation result in a significant change in DKFZP779L1853 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is quantified. Does this perturbation result in a significant change in DKFZP779L1853 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of UBE2V1. Does this perturbation cause a significant change in UBE2V1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of UBE2V1. Does this perturbation cause a significant change in UBE2V1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RP11-16E12.1. Does perturbing TTI1 lead to a significant change in RP11-16E12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RP11-16E12.1. Does perturbing TTI1 lead to a significant change in RP11-16E12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in WHSC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in WHSC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of PITPNB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of PITPNB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in PARP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in PARP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of RP11-242O24.5. Does this perturbation cause a significant change in RP11-242O24.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of RP11-242O24.5. Does this perturbation cause a significant change in RP11-242O24.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2710,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1993,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of BOLA3. Does perturbing EIF2B3 lead to a significant change in BOLA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of BOLA3. Does perturbing EIF2B3 lead to a significant change in BOLA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Determine whether RCBTB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Determine whether RCBTB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5143,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and RAD51AP1 expression is observed. Does this perturbation lead to a significant difference in RAD51AP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and RAD51AP1 expression is observed. Does this perturbation lead to a significant difference in RAD51AP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of PARP11. Does this perturbation cause a significant change in PARP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of PARP11. Does this perturbation cause a significant change in PARP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of KCNE3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of KCNE3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP5 expression is measured. Determine whether ARHGAP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP5 expression is measured. Determine whether ARHGAP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
87,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of PHF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of PHF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ERP29 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ERP29 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1773,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and SDF4 expression is observed. Does this perturbation lead to a significant difference in SDF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and SDF4 expression is observed. Does this perturbation lead to a significant difference in SDF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5153,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ROCK1 expression is observed. Does this perturbation lead to a significant difference in ROCK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ROCK1 expression is observed. Does this perturbation lead to a significant difference in ROCK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1753,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4070,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Does this perturbation cause a significant change in RP1-274L7.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Does this perturbation cause a significant change in RP1-274L7.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CTC-550B14.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CTC-550B14.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of THBS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of THBS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in HAGH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in HAGH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in TRAPPC10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in TRAPPC10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1278,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4100,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Does this perturbation cause a significant change in LINC00938 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Does this perturbation cause a significant change in LINC00938 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in BACH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in BACH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of GMEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of GMEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is measured. Determine whether RBM12B-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is measured. Determine whether RBM12B-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2988,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor AC104532.4 expression. Decide whether this perturbation leads to a significant alteration in AC104532.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor AC104532.4 expression. Decide whether this perturbation leads to a significant alteration in AC104532.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and RCBTB2 expression is measured. Determine whether RCBTB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and RCBTB2 expression is measured. Determine whether RCBTB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in CTNNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in CTNNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4820,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4388,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor GALNT7 expression. Decide whether this perturbation leads to a significant alteration in GALNT7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor GALNT7 expression. Decide whether this perturbation leads to a significant alteration in GALNT7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is quantified. Does this perturbation result in a significant change in RP11-445H22.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is quantified. Does this perturbation result in a significant change in RP11-445H22.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Determine whether LINC00862 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Determine whether LINC00862 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1150,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Does this perturbation cause a significant change in SLC37A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Does this perturbation cause a significant change in SLC37A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in LBX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in LBX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and BACH2 expression is quantified. Does this perturbation result in a significant change in BACH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and BACH2 expression is quantified. Does this perturbation result in a significant change in BACH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2753,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RP11-685N10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-685N10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RP11-685N10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-685N10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
193,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PDE9A expression is observed. Does this perturbation lead to a significant difference in PDE9A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PDE9A expression is observed. Does this perturbation lead to a significant difference in PDE9A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3668,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor EP400 expression. Decide whether this perturbation leads to a significant alteration in EP400 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor EP400 expression. Decide whether this perturbation leads to a significant alteration in EP400 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1680,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and KLK1 expression is quantified. Does this perturbation result in a significant change in KLK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and KLK1 expression is quantified. Does this perturbation result in a significant change in KLK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of DDX3X indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of DDX3X indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in KCTD19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in KCTD19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of AC104532.4. Does perturbing ASCC3 lead to a significant change in AC104532.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of AC104532.4. Does perturbing ASCC3 lead to a significant change in AC104532.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
260,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Does this perturbation cause a significant change in DOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Does this perturbation cause a significant change in DOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
640,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Does this perturbation cause a significant change in KANSL1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Does this perturbation cause a significant change in KANSL1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of RNF19A. Does perturbing PTDSS1 lead to a significant change in RNF19A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of RNF19A. Does perturbing PTDSS1 lead to a significant change in RNF19A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and SEPT5 expression is quantified. Does this perturbation result in a significant change in SEPT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and SEPT5 expression is quantified. Does this perturbation result in a significant change in SEPT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ZNF429 expression is quantified. Does this perturbation result in a significant change in ZNF429 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ZNF429 expression is quantified. Does this perturbation result in a significant change in ZNF429 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of MANF. Does perturbing MRPL39 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of MANF. Does perturbing MRPL39 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2310,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Does this perturbation cause a significant change in ANKLE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Does this perturbation cause a significant change in ANKLE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP13-216E22.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP13-216E22.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and EBI3 expression is quantified. Does this perturbation result in a significant change in EBI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and EBI3 expression is quantified. Does this perturbation result in a significant change in EBI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and UFD1L expression is quantified. Does this perturbation result in a significant change in UFD1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and UFD1L expression is quantified. Does this perturbation result in a significant change in UFD1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ANKRD10 expression is quantified. Does this perturbation result in a significant change in ANKRD10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ANKRD10 expression is quantified. Does this perturbation result in a significant change in ANKRD10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and CTD-2587M2.1 expression is measured. Determine whether CTD-2587M2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and CTD-2587M2.1 expression is measured. Determine whether CTD-2587M2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in BIRC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in BIRC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of GPR146 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of GPR146 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1728,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and PLB1 expression is measured. Determine whether PLB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and PLB1 expression is measured. Determine whether PLB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2208,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CST7 expression. Decide whether this perturbation leads to a significant alteration in CST7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CST7 expression. Decide whether this perturbation leads to a significant alteration in CST7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and UHMK1 expression is quantified. Does this perturbation result in a significant change in UHMK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and UHMK1 expression is quantified. Does this perturbation result in a significant change in UHMK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
780,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Does this perturbation cause a significant change in WHAMM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Does this perturbation cause a significant change in WHAMM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ATXN7L3B. Does perturbing TMED2 lead to a significant change in ATXN7L3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ATXN7L3B. Does perturbing TMED2 lead to a significant change in ATXN7L3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and WARS expression is measured. Determine whether WARS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and WARS expression is measured. Determine whether WARS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4140,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3193,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TRIM24 expression is observed. Does this perturbation lead to a significant difference in TRIM24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TRIM24 expression is observed. Does this perturbation lead to a significant difference in TRIM24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of CRYM. Does perturbing FARSB lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of CRYM. Does perturbing FARSB lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ASPM expression is quantified. Does this perturbation result in a significant change in ASPM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ASPM expression is quantified. Does this perturbation result in a significant change in ASPM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in SERPINF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in SERPINF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1958,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of VAMP2. Does this perturbation cause a significant change in VAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of VAMP2. Does this perturbation cause a significant change in VAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3930,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Does this perturbation cause a significant change in ZXDA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Does this perturbation cause a significant change in ZXDA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3188,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RNF8 expression. Decide whether this perturbation leads to a significant alteration in RNF8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RNF8 expression. Decide whether this perturbation leads to a significant alteration in RNF8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Determine whether NOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Determine whether NOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ZNF789 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ZNF789 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4568,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor WDR3 expression. Decide whether this perturbation leads to a significant alteration in WDR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor WDR3 expression. Decide whether this perturbation leads to a significant alteration in WDR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ATP2A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ATP2A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of OPTN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of OPTN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
99,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is measured. Determine whether RP11-141B14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is measured. Determine whether RP11-141B14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in LRIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in LRIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4408,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RNF8. Does this perturbation cause a significant change in RNF8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RNF8. Does this perturbation cause a significant change in RNF8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1268,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor HOTAIRM1 expression. Decide whether this perturbation leads to a significant alteration in HOTAIRM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor HOTAIRM1 expression. Decide whether this perturbation leads to a significant alteration in HOTAIRM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4043,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and SNHG7 expression is observed. Does this perturbation lead to a significant difference in SNHG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and SNHG7 expression is observed. Does this perturbation lead to a significant difference in SNHG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Determine whether ANKLE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Determine whether ANKLE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Determine whether CDK13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Determine whether CDK13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
733,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and BRWD3 expression is observed. Does this perturbation lead to a significant difference in BRWD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and BRWD3 expression is observed. Does this perturbation lead to a significant difference in BRWD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in STK17B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in STK17B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4358,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ANKRD10 expression. Decide whether this perturbation leads to a significant alteration in ANKRD10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ANKRD10 expression. Decide whether this perturbation leads to a significant alteration in ANKRD10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2533,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of RBM12B-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of RBM12B-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of PSORS1C1. Does perturbing NEDD8 lead to a significant change in PSORS1C1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of PSORS1C1. Does perturbing NEDD8 lead to a significant change in PSORS1C1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1513,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and TMOD3 expression is observed. Does this perturbation lead to a significant difference in TMOD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and TMOD3 expression is observed. Does this perturbation lead to a significant difference in TMOD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of SERPING1. Does perturbing HSPA5 lead to a significant change in SERPING1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of SERPING1. Does perturbing HSPA5 lead to a significant change in SERPING1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RAI14. Does perturbing MARS lead to a significant change in RAI14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RAI14. Does perturbing MARS lead to a significant change in RAI14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Determine whether ZNF341 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Determine whether ZNF341 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in MORF4L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in MORF4L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
353,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1400,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1033,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and TLN1 expression is observed. Does this perturbation lead to a significant difference in TLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and TLN1 expression is observed. Does this perturbation lead to a significant difference in TLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Determine whether GS1-166A23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Determine whether GS1-166A23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Determine whether AC096559.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Determine whether AC096559.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and APOBEC3D expression is measured. Determine whether APOBEC3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and APOBEC3D expression is measured. Determine whether APOBEC3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of QSER1. Does perturbing P4HB lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of QSER1. Does perturbing P4HB lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in EXO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in EXO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and GPRC5C expression is quantified. Does this perturbation result in a significant change in GPRC5C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and GPRC5C expression is quantified. Does this perturbation result in a significant change in GPRC5C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is quantified. Does this perturbation result in a significant change in RP11-435O5.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is quantified. Does this perturbation result in a significant change in RP11-435O5.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Determine whether ZNF789 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Determine whether ZNF789 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of WDR72. Does this perturbation cause a significant change in WDR72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of WDR72. Does this perturbation cause a significant change in WDR72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2093,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TET1. Does this perturbation cause a significant change in TET1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TET1. Does this perturbation cause a significant change in TET1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
898,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor APOL4 expression. Decide whether this perturbation leads to a significant alteration in APOL4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor APOL4 expression. Decide whether this perturbation leads to a significant alteration in APOL4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4798,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ANPEP expression. Decide whether this perturbation leads to a significant alteration in ANPEP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ANPEP expression. Decide whether this perturbation leads to a significant alteration in ANPEP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and GRN expression is quantified. Does this perturbation result in a significant change in GRN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and GRN expression is quantified. Does this perturbation result in a significant change in GRN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2220,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Does this perturbation cause a significant change in GPRC5C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Does this perturbation cause a significant change in GPRC5C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2558,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor MORC2-AS1 expression. Decide whether this perturbation leads to a significant alteration in MORC2-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor MORC2-AS1 expression. Decide whether this perturbation leads to a significant alteration in MORC2-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is measured. Determine whether AC015987.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is measured. Determine whether AC015987.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of EP400. Does perturbing TIMM44 lead to a significant change in EP400 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of EP400. Does perturbing TIMM44 lead to a significant change in EP400 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and SOBP expression is measured. Determine whether SOBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and SOBP expression is measured. Determine whether SOBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Determine whether STK17B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Determine whether STK17B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and SSBP2 expression is quantified. Does this perturbation result in a significant change in SSBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and SSBP2 expression is quantified. Does this perturbation result in a significant change in SSBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RAI14 expression is quantified. Does this perturbation result in a significant change in RAI14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RAI14 expression is quantified. Does this perturbation result in a significant change in RAI14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ATP5EP2. Does perturbing ASCC3 lead to a significant change in ATP5EP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ATP5EP2. Does perturbing ASCC3 lead to a significant change in ATP5EP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA1432 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA1432 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Determine whether MLEC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Determine whether MLEC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
34,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of CASP4. Does this perturbation cause a significant change in CASP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of CASP4. Does this perturbation cause a significant change in CASP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3460,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Does this perturbation cause a significant change in CHST12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Does this perturbation cause a significant change in CHST12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4390,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Does this perturbation cause a significant change in ATAD2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Does this perturbation cause a significant change in ATAD2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and ANKLE2 expression is measured. Determine whether ANKLE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and ANKLE2 expression is measured. Determine whether ANKLE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1313,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Determine whether RP1-274L7.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Determine whether RP1-274L7.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is quantified. Does this perturbation result in a significant change in RP1-274L7.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is quantified. Does this perturbation result in a significant change in RP1-274L7.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Determine whether ITGB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Determine whether ITGB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and TIPARP expression is quantified. Does this perturbation result in a significant change in TIPARP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and TIPARP expression is quantified. Does this perturbation result in a significant change in TIPARP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of PAK1IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of PAK1IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4510,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Does this perturbation cause a significant change in HM13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Does this perturbation cause a significant change in HM13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Determine whether C3AR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Determine whether C3AR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in OBSCN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in OBSCN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3458,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ZFP36L2 expression. Decide whether this perturbation leads to a significant alteration in ZFP36L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ZFP36L2 expression. Decide whether this perturbation leads to a significant alteration in ZFP36L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP13-216E22.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP13-216E22.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of HLTF. Does this perturbation cause a significant change in HLTF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of HLTF. Does this perturbation cause a significant change in HLTF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RP11-157D23.2 expression is measured. Determine whether RP11-157D23.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RP11-157D23.2 expression is measured. Determine whether RP11-157D23.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4870,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Does this perturbation cause a significant change in S100A10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Does this perturbation cause a significant change in S100A10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Determine whether EIF4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Determine whether EIF4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and KLK1 expression is measured. Determine whether KLK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and KLK1 expression is measured. Determine whether KLK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC008074.3 expression is quantified. Does this perturbation result in a significant change in AC008074.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC008074.3 expression is quantified. Does this perturbation result in a significant change in AC008074.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ATXN7L3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ATXN7L3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
413,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and SPINK5 expression is observed. Does this perturbation lead to a significant difference in SPINK5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and SPINK5 expression is observed. Does this perturbation lead to a significant difference in SPINK5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of C10orf32. Does perturbing EIF2B2 lead to a significant change in C10orf32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of C10orf32. Does perturbing EIF2B2 lead to a significant change in C10orf32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of LDLR. Does this perturbation cause a significant change in LDLR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of LDLR. Does this perturbation cause a significant change in LDLR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of WHAMM. Does this perturbation cause a significant change in WHAMM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of WHAMM. Does this perturbation cause a significant change in WHAMM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2458,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor CTNNB1 expression. Decide whether this perturbation leads to a significant alteration in CTNNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor CTNNB1 expression. Decide whether this perturbation leads to a significant alteration in CTNNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PDE3B expression is measured. Determine whether PDE3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PDE3B expression is measured. Determine whether PDE3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Determine whether AC005540.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Determine whether AC005540.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2420,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of RP11-322J23.1. Does perturbing SEC61G lead to a significant change in RP11-322J23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of RP11-322J23.1. Does perturbing SEC61G lead to a significant change in RP11-322J23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of SERPINF2. Does this perturbation cause a significant change in SERPINF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of SERPINF2. Does this perturbation cause a significant change in SERPINF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is quantified. Does this perturbation result in a significant change in RP11-328J2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is quantified. Does this perturbation result in a significant change in RP11-328J2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of UHRF1BP1L. Does perturbing OST4 lead to a significant change in UHRF1BP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of UHRF1BP1L. Does perturbing OST4 lead to a significant change in UHRF1BP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2930,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Does this perturbation cause a significant change in RP11-227G15.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Does this perturbation cause a significant change in RP11-227G15.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ZP3 expression is quantified. Does this perturbation result in a significant change in ZP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ZP3 expression is quantified. Does this perturbation result in a significant change in ZP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and DOCK11 expression is measured. Determine whether DOCK11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and DOCK11 expression is measured. Determine whether DOCK11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Determine whether MED13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Determine whether MED13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of RSL24D1. Does perturbing AMIGO3 lead to a significant change in RSL24D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of RSL24D1. Does perturbing AMIGO3 lead to a significant change in RSL24D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4840,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Does this perturbation cause a significant change in EPS15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Does this perturbation cause a significant change in EPS15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4193,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and CTD-2020K17.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2020K17.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and CTD-2020K17.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2020K17.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EPB42. Does perturbing SYVN1 lead to a significant change in EPB42 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EPB42. Does perturbing SYVN1 lead to a significant change in EPB42 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of MORF4L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of MORF4L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2510,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Does this perturbation cause a significant change in RBM12B-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Does this perturbation cause a significant change in RBM12B-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and LINC01031 expression is measured. Determine whether LINC01031 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and LINC01031 expression is measured. Determine whether LINC01031 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Determine whether RP11-254F7.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Determine whether RP11-254F7.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3920,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Does this perturbation cause a significant change in PPM1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Does this perturbation cause a significant change in PPM1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MLEC. Does perturbing ARHGAP22 lead to a significant change in MLEC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MLEC. Does perturbing ARHGAP22 lead to a significant change in MLEC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ASPM. Does perturbing MANF lead to a significant change in ASPM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ASPM. Does perturbing MANF lead to a significant change in ASPM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Determine whether UBE3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Determine whether UBE3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
360,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Does this perturbation cause a significant change in DOCK11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Does this perturbation cause a significant change in DOCK11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of C12orf23 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of C12orf23 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TTC32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TTC32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of KHDC1L. Does perturbing IARS2 lead to a significant change in KHDC1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of KHDC1L. Does perturbing IARS2 lead to a significant change in KHDC1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4090,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Does this perturbation cause a significant change in DSC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Does this perturbation cause a significant change in DSC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of SRP72. Does perturbing DDRGK1 lead to a significant change in SRP72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of SRP72. Does perturbing DDRGK1 lead to a significant change in SRP72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of KDM1B. Does perturbing UFL1 lead to a significant change in KDM1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of KDM1B. Does perturbing UFL1 lead to a significant change in KDM1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SMIM14. Does perturbing PSMD4 lead to a significant change in SMIM14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SMIM14. Does perturbing PSMD4 lead to a significant change in SMIM14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and NFE2 expression is quantified. Does this perturbation result in a significant change in NFE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and NFE2 expression is quantified. Does this perturbation result in a significant change in NFE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZMYND8 expression is quantified. Does this perturbation result in a significant change in ZMYND8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZMYND8 expression is quantified. Does this perturbation result in a significant change in ZMYND8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5123,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CDT1 expression is observed. Does this perturbation lead to a significant difference in CDT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CDT1 expression is observed. Does this perturbation lead to a significant difference in CDT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of RTN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of RTN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
80,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Does this perturbation cause a significant change in PHF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Does this perturbation cause a significant change in PHF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is quantified. Does this perturbation result in a significant change in RP11-471M2.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is quantified. Does this perturbation result in a significant change in RP11-471M2.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Determine whether KANSL1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Determine whether KANSL1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Determine whether DNASE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Determine whether DNASE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and RP11-430H10.1 expression is quantified. Does this perturbation result in a significant change in RP11-430H10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and RP11-430H10.1 expression is quantified. Does this perturbation result in a significant change in RP11-430H10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3833,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and PLA2G15 expression is observed. Does this perturbation lead to a significant difference in PLA2G15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and PLA2G15 expression is observed. Does this perturbation lead to a significant difference in PLA2G15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1258,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor IL8 expression. Decide whether this perturbation leads to a significant alteration in IL8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor IL8 expression. Decide whether this perturbation leads to a significant alteration in IL8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and F2RL2 expression is quantified. Does this perturbation result in a significant change in F2RL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and F2RL2 expression is quantified. Does this perturbation result in a significant change in F2RL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3913,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and TFPI expression is observed. Does this perturbation lead to a significant difference in TFPI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and TFPI expression is observed. Does this perturbation lead to a significant difference in TFPI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Determine whether RP11-81A22.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Determine whether RP11-81A22.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of DNMBP. Does perturbing TMED10 lead to a significant change in DNMBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of DNMBP. Does perturbing TMED10 lead to a significant change in DNMBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MT2A. Does perturbing ARHGAP22 lead to a significant change in MT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MT2A. Does perturbing ARHGAP22 lead to a significant change in MT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and CELF6 expression is quantified. Does this perturbation result in a significant change in CELF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and CELF6 expression is quantified. Does this perturbation result in a significant change in CELF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Determine whether ZCCHC11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Determine whether ZCCHC11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Determine whether PARP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Determine whether PARP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and C17orf64 expression is measured. Determine whether C17orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and C17orf64 expression is measured. Determine whether C17orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of LDLR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of LDLR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is measured. Determine whether CTD-2020K17.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is measured. Determine whether CTD-2020K17.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of C3AR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of C3AR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in RP11-423O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in RP11-423O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2970,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Does this perturbation cause a significant change in HPCAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Does this perturbation cause a significant change in HPCAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
668,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor PTBP3 expression. Decide whether this perturbation leads to a significant alteration in PTBP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor PTBP3 expression. Decide whether this perturbation leads to a significant alteration in PTBP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in RP11-138C9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in RP11-138C9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2470,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1528,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZMYND8 expression. Decide whether this perturbation leads to a significant alteration in ZMYND8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZMYND8 expression. Decide whether this perturbation leads to a significant alteration in ZMYND8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and DST expression is measured. Determine whether DST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and DST expression is measured. Determine whether DST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and TTC18 expression is measured. Determine whether TTC18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and TTC18 expression is measured. Determine whether TTC18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
818,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor DNTTIP2 expression. Decide whether this perturbation leads to a significant alteration in DNTTIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor DNTTIP2 expression. Decide whether this perturbation leads to a significant alteration in DNTTIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ZEB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ZEB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of GCKR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of GCKR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4913,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CMTM6 expression is observed. Does this perturbation lead to a significant difference in CMTM6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CMTM6 expression is observed. Does this perturbation lead to a significant difference in CMTM6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PTPN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PTPN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of LBX1. Does perturbing PDIA6 lead to a significant change in LBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of LBX1. Does perturbing PDIA6 lead to a significant change in LBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2410,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4678,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor H1FX expression. Decide whether this perturbation leads to a significant alteration in H1FX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor H1FX expression. Decide whether this perturbation leads to a significant alteration in H1FX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is quantified. Does this perturbation result in a significant change in RP11-16E12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is quantified. Does this perturbation result in a significant change in RP11-16E12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of RP11-81A22.5. Does this perturbation cause a significant change in RP11-81A22.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of RP11-81A22.5. Does this perturbation cause a significant change in RP11-81A22.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SNRNP25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SNRNP25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of NFE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of NFE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of WDR3. Does perturbing COPZ1 lead to a significant change in WDR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of WDR3. Does perturbing COPZ1 lead to a significant change in WDR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3073,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PIF1 expression is observed. Does this perturbation lead to a significant difference in PIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PIF1 expression is observed. Does this perturbation lead to a significant difference in PIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of HLA-AS1. Does this perturbation cause a significant change in HLA-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of HLA-AS1. Does this perturbation cause a significant change in HLA-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SP100 expression is measured. Determine whether SP100 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SP100 expression is measured. Determine whether SP100 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4578,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3560,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1550,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Does this perturbation cause a significant change in RP11-381O7.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Does this perturbation cause a significant change in RP11-381O7.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
380,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in HIST1H2BC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in HIST1H2BC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3110,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Does this perturbation cause a significant change in NXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Does this perturbation cause a significant change in NXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ZEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ZEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
71,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of CEBPG. Does perturbing ZNF326 lead to a significant change in CEBPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of CEBPG. Does perturbing ZNF326 lead to a significant change in CEBPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1910,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of AC018878.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of AC018878.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and MYH7B expression is quantified. Does this perturbation result in a significant change in MYH7B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and MYH7B expression is quantified. Does this perturbation result in a significant change in MYH7B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of JARID2. Does this perturbation cause a significant change in JARID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of JARID2. Does this perturbation cause a significant change in JARID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is measured. Determine whether RP11-471M2.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is measured. Determine whether RP11-471M2.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of RAD51AP1. Does perturbing SPCS2 lead to a significant change in RAD51AP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of RAD51AP1. Does perturbing SPCS2 lead to a significant change in RAD51AP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of KCNH7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of KCNH7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of KCTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of KCTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in NAV2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in NAV2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of USP34. Does this perturbation cause a significant change in USP34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of USP34. Does this perturbation cause a significant change in USP34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Determine whether PDE9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Determine whether PDE9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Determine whether GLG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Determine whether GLG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC096559.1. Does this perturbation cause a significant change in AC096559.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC096559.1. Does this perturbation cause a significant change in AC096559.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of KHDC1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of KHDC1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4573,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-65L19.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-65L19.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4760,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in DOCK11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in DOCK11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of RP11-90P5.2. Does perturbing EIF2B4 lead to a significant change in RP11-90P5.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of RP11-90P5.2. Does perturbing EIF2B4 lead to a significant change in RP11-90P5.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4670,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Does this perturbation cause a significant change in H1FX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Does this perturbation cause a significant change in H1FX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Determine whether PIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Determine whether PIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and CFH expression is quantified. Does this perturbation result in a significant change in CFH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and CFH expression is quantified. Does this perturbation result in a significant change in CFH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1128,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-640M9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-640M9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-640M9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-640M9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
7,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ZNF429 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ZNF429 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TET1. Does perturbing BHLHE40 lead to a significant change in TET1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TET1. Does perturbing BHLHE40 lead to a significant change in TET1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GLG1 expression is measured. Determine whether GLG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GLG1 expression is measured. Determine whether GLG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PIF1 expression is measured. Determine whether PIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PIF1 expression is measured. Determine whether PIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and SBF2 expression is measured. Determine whether SBF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and SBF2 expression is measured. Determine whether SBF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ZXDA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ZXDA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3108,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PSMD14 expression. Decide whether this perturbation leads to a significant alteration in PSMD14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PSMD14 expression. Decide whether this perturbation leads to a significant alteration in PSMD14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of RP11-138C9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of RP11-138C9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Determine whether DKFZP779L1853 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Determine whether DKFZP779L1853 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3493,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and DST expression is observed. Does this perturbation lead to a significant difference in DST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and DST expression is observed. Does this perturbation lead to a significant difference in DST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP1-274L7.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP1-274L7.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2778,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4450,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and TMEM87B expression is quantified. Does this perturbation result in a significant change in TMEM87B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and TMEM87B expression is quantified. Does this perturbation result in a significant change in TMEM87B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4000,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2980,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Does this perturbation cause a significant change in AC104532.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Does this perturbation cause a significant change in AC104532.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of EXO1. Does perturbing SEC61B lead to a significant change in EXO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of EXO1. Does perturbing SEC61B lead to a significant change in EXO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
730,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Does this perturbation cause a significant change in BRWD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Does this perturbation cause a significant change in BRWD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and FCGRT expression is measured. Determine whether FCGRT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and FCGRT expression is measured. Determine whether FCGRT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EXOC3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EXOC3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of BRWD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of BRWD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of TSNAXIP1. Does perturbing DAD1 lead to a significant change in TSNAXIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of TSNAXIP1. Does perturbing DAD1 lead to a significant change in TSNAXIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ERP29. Does perturbing SPCS3 lead to a significant change in ERP29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ERP29. Does perturbing SPCS3 lead to a significant change in ERP29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in OR2T6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in OR2T6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Determine whether RP11-132A1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Determine whether RP11-132A1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1083,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and DDX3X expression is observed. Does this perturbation lead to a significant difference in DDX3X expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and DDX3X expression is observed. Does this perturbation lead to a significant difference in DDX3X expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of CTSF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of CTSF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
72,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and CEBPG expression is quantified. Does this perturbation result in a significant change in CEBPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and CEBPG expression is quantified. Does this perturbation result in a significant change in CEBPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Determine whether PAK1IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Determine whether PAK1IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3030,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Does this perturbation cause a significant change in RP11-838N2.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Does this perturbation cause a significant change in RP11-838N2.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4430,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of CTD-2001C12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of CTD-2001C12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ZNF341 expression is measured. Determine whether ZNF341 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ZNF341 expression is measured. Determine whether ZNF341 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3688,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor SLC27A2 expression. Decide whether this perturbation leads to a significant alteration in SLC27A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor SLC27A2 expression. Decide whether this perturbation leads to a significant alteration in SLC27A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ATF6. Does perturbing AMIGO3 lead to a significant change in ATF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ATF6. Does perturbing AMIGO3 lead to a significant change in ATF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Determine whether TROAP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Determine whether TROAP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and STARD9 expression is quantified. Does this perturbation result in a significant change in STARD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and STARD9 expression is quantified. Does this perturbation result in a significant change in STARD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2603,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CTCFL expression is observed. Does this perturbation lead to a significant difference in CTCFL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CTCFL expression is observed. Does this perturbation lead to a significant difference in CTCFL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and RP11-146D12.2 expression is quantified. Does this perturbation result in a significant change in RP11-146D12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and RP11-146D12.2 expression is quantified. Does this perturbation result in a significant change in RP11-146D12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2873,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and RGS3 expression is observed. Does this perturbation lead to a significant difference in RGS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and RGS3 expression is observed. Does this perturbation lead to a significant difference in RGS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1708,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor UBE2V1 expression. Decide whether this perturbation leads to a significant alteration in UBE2V1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor UBE2V1 expression. Decide whether this perturbation leads to a significant alteration in UBE2V1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
75,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in CEBPG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in CEBPG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1488,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor WHSC1 expression. Decide whether this perturbation leads to a significant alteration in WHSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor WHSC1 expression. Decide whether this perturbation leads to a significant alteration in WHSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NUF2. Does perturbing SAMM50 lead to a significant change in NUF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NUF2. Does perturbing SAMM50 lead to a significant change in NUF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ATF7IP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ATF7IP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4583,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of F2RL2. Does perturbing TELO2 lead to a significant change in F2RL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of F2RL2. Does perturbing TELO2 lead to a significant change in F2RL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3013,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in EP400 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in EP400 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and COPB1 expression is quantified. Does this perturbation result in a significant change in COPB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and COPB1 expression is quantified. Does this perturbation result in a significant change in COPB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Determine whether PPM1N shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Determine whether PPM1N shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Determine whether PHF21A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Determine whether PHF21A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC096559.1. Does perturbing CAD lead to a significant change in AC096559.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC096559.1. Does perturbing CAD lead to a significant change in AC096559.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3838,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor PLA2G15 expression. Decide whether this perturbation leads to a significant alteration in PLA2G15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor PLA2G15 expression. Decide whether this perturbation leads to a significant alteration in PLA2G15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3910,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Does this perturbation cause a significant change in TFPI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Does this perturbation cause a significant change in TFPI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
330,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ATP5EP2 expression is quantified. Does this perturbation result in a significant change in ATP5EP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ATP5EP2 expression is quantified. Does this perturbation result in a significant change in ATP5EP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of LINC00862. Does this perturbation cause a significant change in LINC00862 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of LINC00862. Does this perturbation cause a significant change in LINC00862 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in KHDC1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in KHDC1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and STK17B expression is quantified. Does this perturbation result in a significant change in STK17B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and STK17B expression is quantified. Does this perturbation result in a significant change in STK17B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2388,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor DKFZP779L1853 expression. Decide whether this perturbation leads to a significant alteration in DKFZP779L1853 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor DKFZP779L1853 expression. Decide whether this perturbation leads to a significant alteration in DKFZP779L1853 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CD83 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CD83 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and LINC01137 expression is measured. Determine whether LINC01137 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and LINC01137 expression is measured. Determine whether LINC01137 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Determine whether RP11-499F3.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Determine whether RP11-499F3.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1600,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Does this perturbation cause a significant change in ATP6V1B2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Does this perturbation cause a significant change in ATP6V1B2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in DYNC1H1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in DYNC1H1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of LTN1. Does perturbing HYOU1 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of LTN1. Does perturbing HYOU1 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3598,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP11-2H8.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-2H8.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP11-2H8.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-2H8.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Determine whether RP11-65L19.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Determine whether RP11-65L19.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
68,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RIOK3 expression. Decide whether this perturbation leads to a significant alteration in RIOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RIOK3 expression. Decide whether this perturbation leads to a significant alteration in RIOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of RBM12B-AS1. Does this perturbation cause a significant change in RBM12B-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of RBM12B-AS1. Does this perturbation cause a significant change in RBM12B-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PTAR1 expression is quantified. Does this perturbation result in a significant change in PTAR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PTAR1 expression is quantified. Does this perturbation result in a significant change in PTAR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-640M9.1. Does this perturbation cause a significant change in RP11-640M9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-640M9.1. Does this perturbation cause a significant change in RP11-640M9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3993,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and RP11-242O24.5 expression is observed. Does this perturbation lead to a significant difference in RP11-242O24.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and RP11-242O24.5 expression is observed. Does this perturbation lead to a significant difference in RP11-242O24.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and AC012594.1 expression is quantified. Does this perturbation result in a significant change in AC012594.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and AC012594.1 expression is quantified. Does this perturbation result in a significant change in AC012594.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and UBE3A expression is measured. Determine whether UBE3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and UBE3A expression is measured. Determine whether UBE3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and PKDCC expression is quantified. Does this perturbation result in a significant change in PKDCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and PKDCC expression is quantified. Does this perturbation result in a significant change in PKDCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ASPM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ASPM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
11,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of P4HA2. Does perturbing CREB1 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of P4HA2. Does perturbing CREB1 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of GPRC5C. Does perturbing NEDD8 lead to a significant change in GPRC5C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of GPRC5C. Does perturbing NEDD8 lead to a significant change in GPRC5C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and SPCS2 expression is quantified. Does this perturbation result in a significant change in SPCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and SPCS2 expression is quantified. Does this perturbation result in a significant change in SPCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4723,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and RP11-322J23.1 expression is observed. Does this perturbation lead to a significant difference in RP11-322J23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and RP11-322J23.1 expression is observed. Does this perturbation lead to a significant difference in RP11-322J23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of PLA2G15. Does perturbing HYOU1 lead to a significant change in PLA2G15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of PLA2G15. Does perturbing HYOU1 lead to a significant change in PLA2G15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2623,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and MORF4L2 expression is observed. Does this perturbation lead to a significant difference in MORF4L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and MORF4L2 expression is observed. Does this perturbation lead to a significant difference in MORF4L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
498,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor LDLR expression. Decide whether this perturbation leads to a significant alteration in LDLR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor LDLR expression. Decide whether this perturbation leads to a significant alteration in LDLR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RIMS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RIMS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of PTGS1. Does perturbing SCYL1 lead to a significant change in PTGS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of PTGS1. Does perturbing SCYL1 lead to a significant change in PTGS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and NUFIP2 expression is quantified. Does this perturbation result in a significant change in NUFIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and NUFIP2 expression is quantified. Does this perturbation result in a significant change in NUFIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of KLF6. Does perturbing TELO2 lead to a significant change in KLF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of KLF6. Does perturbing TELO2 lead to a significant change in KLF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in HP1BP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in HP1BP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1623,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ATP6AP2 expression is observed. Does this perturbation lead to a significant difference in ATP6AP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ATP6AP2 expression is observed. Does this perturbation lead to a significant difference in ATP6AP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ATF6. Does this perturbation cause a significant change in ATF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ATF6. Does this perturbation cause a significant change in ATF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-423O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-423O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Determine whether FOXO6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Determine whether FOXO6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Determine whether HIST1H1D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Determine whether HIST1H1D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PTPRC. Does this perturbation cause a significant change in PTPRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PTPRC. Does this perturbation cause a significant change in PTPRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PCF11. Does perturbing YIPF5 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PCF11. Does perturbing YIPF5 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
53,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and C6orf48 expression is observed. Does this perturbation lead to a significant difference in C6orf48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and C6orf48 expression is observed. Does this perturbation lead to a significant difference in C6orf48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SNRNP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SNRNP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CTD-2521M24.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CTD-2521M24.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is quantified. Does this perturbation result in a significant change in RP11-119J18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is quantified. Does this perturbation result in a significant change in RP11-119J18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of DUSP21. Does perturbing MARS lead to a significant change in DUSP21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of DUSP21. Does perturbing MARS lead to a significant change in DUSP21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
928,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1973,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and CRNDE expression is observed. Does this perturbation lead to a significant difference in CRNDE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and CRNDE expression is observed. Does this perturbation lead to a significant difference in CRNDE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3623,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5010,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Does this perturbation cause a significant change in THBS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Does this perturbation cause a significant change in THBS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PSMC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PSMC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3173,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MLEC expression is observed. Does this perturbation lead to a significant difference in MLEC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MLEC expression is observed. Does this perturbation lead to a significant difference in MLEC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of TXNIP. Does perturbing TMED10 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of TXNIP. Does perturbing TMED10 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IFT27 expression is measured. Determine whether IFT27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IFT27 expression is measured. Determine whether IFT27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ASPM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ASPM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4693,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and ANKRD11 expression is observed. Does this perturbation lead to a significant difference in ANKRD11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and ANKRD11 expression is observed. Does this perturbation lead to a significant difference in ANKRD11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Determine whether RP11-304M2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Determine whether RP11-304M2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Determine whether ZP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Determine whether ZP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KIAA1586 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KIAA1586 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DOK3 expression is measured. Determine whether DOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DOK3 expression is measured. Determine whether DOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-363D14.1. Does this perturbation cause a significant change in RP11-363D14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-363D14.1. Does this perturbation cause a significant change in RP11-363D14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA1432 expression is quantified. Does this perturbation result in a significant change in KIAA1432 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA1432 expression is quantified. Does this perturbation result in a significant change in KIAA1432 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Determine whether HPCAL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Determine whether HPCAL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and KDM1B expression is quantified. Does this perturbation result in a significant change in KDM1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and KDM1B expression is quantified. Does this perturbation result in a significant change in KDM1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Determine whether TAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Determine whether TAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
57,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of C6orf48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of C6orf48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and PDK2 expression is measured. Determine whether PDK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and PDK2 expression is measured. Determine whether PDK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is measured. Determine whether CTD-2267D19.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is measured. Determine whether CTD-2267D19.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of LST1. Does perturbing SYVN1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of LST1. Does perturbing SYVN1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Determine whether COPB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Determine whether COPB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of NOSTRIN. Does this perturbation cause a significant change in NOSTRIN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of NOSTRIN. Does this perturbation cause a significant change in NOSTRIN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and SNHG7 expression is measured. Determine whether SNHG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and SNHG7 expression is measured. Determine whether SNHG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CLINT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CLINT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of CD46. Does this perturbation cause a significant change in CD46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of CD46. Does this perturbation cause a significant change in CD46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
673,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and MEX3B expression is observed. Does this perturbation lead to a significant difference in MEX3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and MEX3B expression is observed. Does this perturbation lead to a significant difference in MEX3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and EXO1 expression is measured. Determine whether EXO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and EXO1 expression is measured. Determine whether EXO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
18,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in KIAA1731 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in KIAA1731 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ADAMTS10 expression is measured. Determine whether ADAMTS10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ADAMTS10 expression is measured. Determine whether ADAMTS10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
983,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and TOB2 expression is observed. Does this perturbation lead to a significant difference in TOB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and TOB2 expression is observed. Does this perturbation lead to a significant difference in TOB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4983,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and UHMK1 expression is observed. Does this perturbation lead to a significant difference in UHMK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and UHMK1 expression is observed. Does this perturbation lead to a significant difference in UHMK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of NBEAL2. Does this perturbation cause a significant change in NBEAL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of NBEAL2. Does this perturbation cause a significant change in NBEAL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1398,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NUF2 expression. Decide whether this perturbation leads to a significant alteration in NUF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NUF2 expression. Decide whether this perturbation leads to a significant alteration in NUF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
270,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Does this perturbation cause a significant change in DUT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Does this perturbation cause a significant change in DUT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of CYP17A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of CYP17A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of RP11-573D15.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of RP11-573D15.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and NFE2 expression is measured. Determine whether NFE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and NFE2 expression is measured. Determine whether NFE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of MED13. Does perturbing AARS lead to a significant change in MED13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of MED13. Does perturbing AARS lead to a significant change in MED13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
830,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Does this perturbation cause a significant change in RP11-138C9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Does this perturbation cause a significant change in RP11-138C9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of POU2F2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of POU2F2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and NINJ2 expression is quantified. Does this perturbation result in a significant change in NINJ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and NINJ2 expression is quantified. Does this perturbation result in a significant change in NINJ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1950,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is measured. Determine whether DYNC1H1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is measured. Determine whether DYNC1H1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ABI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ABI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and MYH7B expression is measured. Determine whether MYH7B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and MYH7B expression is measured. Determine whether MYH7B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in P4HB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in P4HB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and VPS41 expression is measured. Determine whether VPS41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and VPS41 expression is measured. Determine whether VPS41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RILPL2. Does perturbing HSD17B12 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RILPL2. Does perturbing HSD17B12 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Determine whether ADAMTS10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Determine whether ADAMTS10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Determine whether TET1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Determine whether TET1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of DNASE2. Does this perturbation cause a significant change in DNASE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of DNASE2. Does this perturbation cause a significant change in DNASE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3540,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Does this perturbation cause a significant change in SEPT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Does this perturbation cause a significant change in SEPT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in GS1-166A23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in GS1-166A23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ACE expression is measured. Determine whether ACE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ACE expression is measured. Determine whether ACE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in PDK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in PDK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of CD58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of CD58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4533,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and RP11-304M2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-304M2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and RP11-304M2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-304M2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3163,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MT2A expression is observed. Does this perturbation lead to a significant difference in MT2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MT2A expression is observed. Does this perturbation lead to a significant difference in MT2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and PRRC2B expression is quantified. Does this perturbation result in a significant change in PRRC2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and PRRC2B expression is quantified. Does this perturbation result in a significant change in PRRC2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
493,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and LDLR expression is observed. Does this perturbation lead to a significant difference in LDLR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and LDLR expression is observed. Does this perturbation lead to a significant difference in LDLR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1830,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Does this perturbation cause a significant change in ATP2A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Does this perturbation cause a significant change in ATP2A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and PAK1IP1 expression is quantified. Does this perturbation result in a significant change in PAK1IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and PAK1IP1 expression is quantified. Does this perturbation result in a significant change in PAK1IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CPQ. Does perturbing ASCC3 lead to a significant change in CPQ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CPQ. Does perturbing ASCC3 lead to a significant change in CPQ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1683,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and MED13 expression is quantified. Does this perturbation result in a significant change in MED13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and MED13 expression is quantified. Does this perturbation result in a significant change in MED13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1693,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CTBS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CTBS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Determine whether NUF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Determine whether NUF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of WHSC1. Does this perturbation cause a significant change in WHSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of WHSC1. Does this perturbation cause a significant change in WHSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ATP6AP2. Does this perturbation cause a significant change in ATP6AP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ATP6AP2. Does this perturbation cause a significant change in ATP6AP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in POU2F2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in POU2F2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3080,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
29,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SMIM14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SMIM14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Determine whether PTPRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Determine whether PTPRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of CASP8. Does perturbing DDIT3 lead to a significant change in CASP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of CASP8. Does perturbing DDIT3 lead to a significant change in CASP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Determine whether OR2T6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Determine whether OR2T6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of IL2RB. Does perturbing EIF2S1 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of IL2RB. Does perturbing EIF2S1 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RP11-157D23.2. Does perturbing FECH lead to a significant change in RP11-157D23.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RP11-157D23.2. Does perturbing FECH lead to a significant change in RP11-157D23.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of C17orf64. Does perturbing TIMM44 lead to a significant change in C17orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of C17orf64. Does perturbing TIMM44 lead to a significant change in C17orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of RP11-435O5.4. Does perturbing UFL1 lead to a significant change in RP11-435O5.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of RP11-435O5.4. Does perturbing UFL1 lead to a significant change in RP11-435O5.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of ZFHX3. Does perturbing TTI2 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of ZFHX3. Does perturbing TTI2 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of LTB. Does perturbing SEC61G lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of LTB. Does perturbing SEC61G lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3228,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ZNF789 expression. Decide whether this perturbation leads to a significant alteration in ZNF789 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ZNF789 expression. Decide whether this perturbation leads to a significant alteration in ZNF789 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GUSB. Does perturbing TMEM167A lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GUSB. Does perturbing TMEM167A lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Determine whether RP11-445H22.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Determine whether RP11-445H22.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1758,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RP11-685N10.1 expression is quantified. Does this perturbation result in a significant change in RP11-685N10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RP11-685N10.1 expression is quantified. Does this perturbation result in a significant change in RP11-685N10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of CTNNB1. Does perturbing MRPL39 lead to a significant change in CTNNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of CTNNB1. Does perturbing MRPL39 lead to a significant change in CTNNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
9,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ZNF429 expression is measured. Determine whether ZNF429 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ZNF429 expression is measured. Determine whether ZNF429 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CST7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CST7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Determine whether LRIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Determine whether LRIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Determine whether RP11-242O24.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Determine whether RP11-242O24.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2570,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Does this perturbation cause a significant change in ACE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Does this perturbation cause a significant change in ACE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3328,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor NPAT expression. Decide whether this perturbation leads to a significant alteration in NPAT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor NPAT expression. Decide whether this perturbation leads to a significant alteration in NPAT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of KLF6. Does this perturbation cause a significant change in KLF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of KLF6. Does this perturbation cause a significant change in KLF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KIAA1586. Does this perturbation cause a significant change in KIAA1586 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KIAA1586. Does this perturbation cause a significant change in KIAA1586 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and LINC00938 expression is measured. Determine whether LINC00938 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and LINC00938 expression is measured. Determine whether LINC00938 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3568,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1883,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1803,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and LTBP1 expression is observed. Does this perturbation lead to a significant difference in LTBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and LTBP1 expression is observed. Does this perturbation lead to a significant difference in LTBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of AC018878.3. Does perturbing HSPA5 lead to a significant change in AC018878.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of AC018878.3. Does perturbing HSPA5 lead to a significant change in AC018878.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HRK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HRK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4338,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor GRN expression. Decide whether this perturbation leads to a significant alteration in GRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor GRN expression. Decide whether this perturbation leads to a significant alteration in GRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP3-465N24.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP3-465N24.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of AC079466.1. Does perturbing MRGBP lead to a significant change in AC079466.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of AC079466.1. Does perturbing MRGBP lead to a significant change in AC079466.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of KCNE3. Does perturbing IDH3A lead to a significant change in KCNE3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of KCNE3. Does perturbing IDH3A lead to a significant change in KCNE3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5050,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of AC012594.1. Does this perturbation cause a significant change in AC012594.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of AC012594.1. Does this perturbation cause a significant change in AC012594.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of HIST1H1D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of HIST1H1D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3940,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Does this perturbation cause a significant change in ROBO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Does this perturbation cause a significant change in ROBO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
783,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and WHAMM expression is observed. Does this perturbation lead to a significant difference in WHAMM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and WHAMM expression is observed. Does this perturbation lead to a significant difference in WHAMM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of WARS is measured. Determine whether WARS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of WARS is measured. Determine whether WARS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of VIMP. Does perturbing IDH3A lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of VIMP. Does perturbing IDH3A lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and PIK3R3 expression is measured. Determine whether PIK3R3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and PIK3R3 expression is measured. Determine whether PIK3R3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1483,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and WHSC1 expression is observed. Does this perturbation lead to a significant difference in WHSC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and WHSC1 expression is observed. Does this perturbation lead to a significant difference in WHSC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
750,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Does this perturbation cause a significant change in TSNAXIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Does this perturbation cause a significant change in TSNAXIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3270,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Does this perturbation cause a significant change in TSC22D4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Does this perturbation cause a significant change in TSC22D4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
233,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PTPRC expression is observed. Does this perturbation lead to a significant difference in PTPRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PTPRC expression is observed. Does this perturbation lead to a significant difference in PTPRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in UQCRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in UQCRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3098,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor GNPTG expression. Decide whether this perturbation leads to a significant alteration in GNPTG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor GNPTG expression. Decide whether this perturbation leads to a significant alteration in GNPTG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3658,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor KCNJ13 expression. Decide whether this perturbation leads to a significant alteration in KCNJ13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor KCNJ13 expression. Decide whether this perturbation leads to a significant alteration in KCNJ13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1843,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and OR2T6 expression is observed. Does this perturbation lead to a significant difference in OR2T6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and OR2T6 expression is observed. Does this perturbation lead to a significant difference in OR2T6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1388,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ZEB1 expression. Decide whether this perturbation leads to a significant alteration in ZEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ZEB1 expression. Decide whether this perturbation leads to a significant alteration in ZEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1678,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor AC012594.1 expression. Decide whether this perturbation leads to a significant alteration in AC012594.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor AC012594.1 expression. Decide whether this perturbation leads to a significant alteration in AC012594.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and SERPING1 expression is quantified. Does this perturbation result in a significant change in SERPING1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and SERPING1 expression is quantified. Does this perturbation result in a significant change in SERPING1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of RP11-146D12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of RP11-146D12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and KIAA1731 expression is measured. Determine whether KIAA1731 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and KIAA1731 expression is measured. Determine whether KIAA1731 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of PCF11. Does perturbing SPCS3 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of PCF11. Does perturbing SPCS3 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
283,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and CDRT4 expression is observed. Does this perturbation lead to a significant difference in CDRT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and CDRT4 expression is observed. Does this perturbation lead to a significant difference in CDRT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2330,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Does this perturbation cause a significant change in F2RL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Does this perturbation cause a significant change in F2RL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4763,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3308,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SMIM14 expression. Decide whether this perturbation leads to a significant alteration in SMIM14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SMIM14 expression. Decide whether this perturbation leads to a significant alteration in SMIM14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of LINC00938. Does perturbing UFM1 lead to a significant change in LINC00938 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of LINC00938. Does perturbing UFM1 lead to a significant change in LINC00938 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Determine whether KLF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Determine whether KLF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and KDM1B expression is measured. Determine whether KDM1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and KDM1B expression is measured. Determine whether KDM1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in AC012594.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in AC012594.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3593,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP11-2H8.2 expression is observed. Does this perturbation lead to a significant difference in RP11-2H8.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP11-2H8.2 expression is observed. Does this perturbation lead to a significant difference in RP11-2H8.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RP11-157D23.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RP11-157D23.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of JARID2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of JARID2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Determine whether TRIM38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Determine whether TRIM38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of CYP17A1-AS1. Does perturbing DDRGK1 lead to a significant change in CYP17A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of CYP17A1-AS1. Does perturbing DDRGK1 lead to a significant change in CYP17A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is quantified. Does this perturbation result in a significant change in RP11-247A12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is quantified. Does this perturbation result in a significant change in RP11-247A12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CDT1 expression is measured. Determine whether CDT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CDT1 expression is measured. Determine whether CDT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3180,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Does this perturbation cause a significant change in RNF8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Does this perturbation cause a significant change in RNF8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of POLR2J3. Does this perturbation cause a significant change in POLR2J3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of POLR2J3. Does this perturbation cause a significant change in POLR2J3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EGLN3. Does perturbing PSMD4 lead to a significant change in EGLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EGLN3. Does perturbing PSMD4 lead to a significant change in EGLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and DUSP21 expression is measured. Determine whether DUSP21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and DUSP21 expression is measured. Determine whether DUSP21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PDE4D. Does perturbing IER3IP1 lead to a significant change in PDE4D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PDE4D. Does perturbing IER3IP1 lead to a significant change in PDE4D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3973,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and SEC23IP expression is observed. Does this perturbation lead to a significant difference in SEC23IP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and SEC23IP expression is observed. Does this perturbation lead to a significant difference in SEC23IP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5053,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and CFH expression is observed. Does this perturbation lead to a significant difference in CFH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and CFH expression is observed. Does this perturbation lead to a significant difference in CFH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Determine whether ATAD2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Determine whether ATAD2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1810,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Does this perturbation cause a significant change in NFAT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Does this perturbation cause a significant change in NFAT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of SEPT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of SEPT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Determine whether RP11-90P5.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Determine whether RP11-90P5.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of SAMM50. Does perturbing HARS lead to a significant change in SAMM50 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of SAMM50. Does perturbing HARS lead to a significant change in SAMM50 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NPDC1. Does perturbing STT3A lead to a significant change in NPDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NPDC1. Does perturbing STT3A lead to a significant change in NPDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of RP11-666A20.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of RP11-666A20.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1298,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor RP11-573D15.9 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor RP11-573D15.9 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
563,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and IL32 expression is observed. Does this perturbation lead to a significant difference in IL32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and IL32 expression is observed. Does this perturbation lead to a significant difference in IL32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1703,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and UBE2V1 expression is observed. Does this perturbation lead to a significant difference in UBE2V1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and UBE2V1 expression is observed. Does this perturbation lead to a significant difference in UBE2V1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and TROAP expression is quantified. Does this perturbation result in a significant change in TROAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and TROAP expression is quantified. Does this perturbation result in a significant change in TROAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
19,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of PHLDA2. Does perturbing COPZ1 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of PHLDA2. Does perturbing COPZ1 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
113,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-65L19.4 expression is observed. Does this perturbation lead to a significant difference in RP11-65L19.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-65L19.4 expression is observed. Does this perturbation lead to a significant difference in RP11-65L19.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of PPM1N. Does this perturbation cause a significant change in PPM1N expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of PPM1N. Does this perturbation cause a significant change in PPM1N expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2260,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Does this perturbation cause a significant change in C6orf120 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Does this perturbation cause a significant change in C6orf120 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4173,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and FGF11 expression is observed. Does this perturbation lead to a significant difference in FGF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and FGF11 expression is observed. Does this perturbation lead to a significant difference in FGF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RP11-24F11.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RP11-24F11.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of JARID2. Does perturbing DDRGK1 lead to a significant change in JARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of JARID2. Does perturbing DDRGK1 lead to a significant change in JARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of CD58. Does perturbing GBF1 lead to a significant change in CD58 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of CD58. Does perturbing GBF1 lead to a significant change in CD58 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and TFPI expression is measured. Determine whether TFPI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and TFPI expression is measured. Determine whether TFPI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and TTC18 expression is quantified. Does this perturbation result in a significant change in TTC18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and TTC18 expression is quantified. Does this perturbation result in a significant change in TTC18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP11-15E18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP11-15E18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of LINC01031. Does perturbing CHERP lead to a significant change in LINC01031 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of LINC01031. Does perturbing CHERP lead to a significant change in LINC01031 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2853,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and OXLD1 expression is observed. Does this perturbation lead to a significant difference in OXLD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and OXLD1 expression is observed. Does this perturbation lead to a significant difference in OXLD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HMGCS1. Does this perturbation cause a significant change in HMGCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HMGCS1. Does this perturbation cause a significant change in HMGCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ZC3H7A. Does perturbing TIMM44 lead to a significant change in ZC3H7A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ZC3H7A. Does perturbing TIMM44 lead to a significant change in ZC3H7A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is measured. Determine whether RP11-3D4.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is measured. Determine whether RP11-3D4.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
42,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and LPAR5 expression is quantified. Does this perturbation result in a significant change in LPAR5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and LPAR5 expression is quantified. Does this perturbation result in a significant change in LPAR5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4710,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Does this perturbation cause a significant change in TAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Does this perturbation cause a significant change in TAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3620,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
63,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RIOK3 expression is observed. Does this perturbation lead to a significant difference in RIOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RIOK3 expression is observed. Does this perturbation lead to a significant difference in RIOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of VPS41. Does perturbing HARS lead to a significant change in VPS41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of VPS41. Does perturbing HARS lead to a significant change in VPS41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TUBA1C. Does perturbing SRP72 lead to a significant change in TUBA1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TUBA1C. Does perturbing SRP72 lead to a significant change in TUBA1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and DSC2 expression is quantified. Does this perturbation result in a significant change in DSC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and DSC2 expression is quantified. Does this perturbation result in a significant change in DSC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
988,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor TOB2 expression. Decide whether this perturbation leads to a significant alteration in TOB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor TOB2 expression. Decide whether this perturbation leads to a significant alteration in TOB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4270,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of IDS is measured. Does this perturbation cause a significant change in IDS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of IDS is measured. Does this perturbation cause a significant change in IDS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4720,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Does this perturbation cause a significant change in RP11-322J23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Does this perturbation cause a significant change in RP11-322J23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of RP11-471M2.3. Does perturbing SEC63 lead to a significant change in RP11-471M2.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of RP11-471M2.3. Does perturbing SEC63 lead to a significant change in RP11-471M2.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and CCRL2 expression is measured. Determine whether CCRL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and CCRL2 expression is measured. Determine whether CCRL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
59,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and C6orf48 expression is measured. Determine whether C6orf48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and C6orf48 expression is measured. Determine whether C6orf48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3310,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Does this perturbation cause a significant change in EGLN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Does this perturbation cause a significant change in EGLN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of NOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of NOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ZXDA. Does this perturbation cause a significant change in ZXDA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ZXDA. Does this perturbation cause a significant change in ZXDA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2650,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Does this perturbation cause a significant change in IFNGR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Does this perturbation cause a significant change in IFNGR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
470,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Does this perturbation cause a significant change in RP11-146D12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Does this perturbation cause a significant change in RP11-146D12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4398,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ATAD2B expression. Decide whether this perturbation leads to a significant alteration in ATAD2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ATAD2B expression. Decide whether this perturbation leads to a significant alteration in ATAD2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Determine whether TUBA1C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Determine whether TUBA1C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of RGS20. Does perturbing TMED2 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of RGS20. Does perturbing TMED2 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of RP11-471M2.3. Does this perturbation cause a significant change in RP11-471M2.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of RP11-471M2.3. Does this perturbation cause a significant change in RP11-471M2.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
208,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor KLK1 expression. Decide whether this perturbation leads to a significant alteration in KLK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor KLK1 expression. Decide whether this perturbation leads to a significant alteration in KLK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of CCRL2. Does this perturbation cause a significant change in CCRL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of CCRL2. Does this perturbation cause a significant change in CCRL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1100,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Determine whether PDRG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Determine whether PDRG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of HM13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of HM13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3008,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RUNX1. Does perturbing MARS lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RUNX1. Does perturbing MARS lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Determine whether HMGCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Determine whether HMGCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in IL32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in IL32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
81,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of PHF3. Does perturbing ZNF326 lead to a significant change in PHF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of PHF3. Does perturbing ZNF326 lead to a significant change in PHF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4908,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CHD3 expression. Decide whether this perturbation leads to a significant alteration in CHD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CHD3 expression. Decide whether this perturbation leads to a significant alteration in CHD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP5. Does this perturbation cause a significant change in ARHGAP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP5. Does this perturbation cause a significant change in ARHGAP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of REST. Does perturbing TIMM23 lead to a significant change in REST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of REST. Does perturbing TIMM23 lead to a significant change in REST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of TIPARP. Does perturbing EIF2S1 lead to a significant change in TIPARP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of TIPARP. Does perturbing EIF2S1 lead to a significant change in TIPARP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is quantified. Does this perturbation result in a significant change in GS1-166A23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is quantified. Does this perturbation result in a significant change in GS1-166A23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of GDF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of GDF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is quantified. Does this perturbation result in a significant change in ARHGAP11A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is quantified. Does this perturbation result in a significant change in ARHGAP11A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of STK17B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of STK17B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of VPS41. Does this perturbation cause a significant change in VPS41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of VPS41. Does this perturbation cause a significant change in VPS41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of TLK2. Does perturbing DNAJC19 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of TLK2. Does perturbing DNAJC19 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4640,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3383,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TRIM38 expression is observed. Does this perturbation lead to a significant difference in TRIM38 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TRIM38 expression is observed. Does this perturbation lead to a significant difference in TRIM38 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Determine whether CTSV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Determine whether CTSV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5038,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor CELF6 expression. Decide whether this perturbation leads to a significant alteration in CELF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor CELF6 expression. Decide whether this perturbation leads to a significant alteration in CELF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and TFPI expression is quantified. Does this perturbation result in a significant change in TFPI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and TFPI expression is quantified. Does this perturbation result in a significant change in TFPI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of CFH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of CFH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and HAGH expression is quantified. Does this perturbation result in a significant change in HAGH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and HAGH expression is quantified. Does this perturbation result in a significant change in HAGH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5130,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Does this perturbation cause a significant change in CTC-308K20.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Does this perturbation cause a significant change in CTC-308K20.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of P4HB. Does this perturbation cause a significant change in P4HB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of P4HB. Does this perturbation cause a significant change in P4HB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and NAV1 expression is quantified. Does this perturbation result in a significant change in NAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and NAV1 expression is quantified. Does this perturbation result in a significant change in NAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Determine whether REST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Determine whether REST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
173,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TKTL1 expression is observed. Does this perturbation lead to a significant difference in TKTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TKTL1 expression is observed. Does this perturbation lead to a significant difference in TKTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2333,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and F2RL2 expression is observed. Does this perturbation lead to a significant difference in F2RL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and F2RL2 expression is observed. Does this perturbation lead to a significant difference in F2RL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in PTBP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in PTBP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Determine whether AC079466.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Determine whether AC079466.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of S100A10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of S100A10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NSD1 expression is measured. Determine whether NSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NSD1 expression is measured. Determine whether NSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2338,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor F2RL2 expression. Decide whether this perturbation leads to a significant alteration in F2RL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor F2RL2 expression. Decide whether this perturbation leads to a significant alteration in F2RL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-328J2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-328J2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Determine whether CELF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Determine whether CELF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3300,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Does this perturbation cause a significant change in SMIM14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Does this perturbation cause a significant change in SMIM14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of APOBEC3D. Does this perturbation cause a significant change in APOBEC3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of APOBEC3D. Does this perturbation cause a significant change in APOBEC3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AC015987.1 expression is quantified. Does this perturbation result in a significant change in AC015987.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AC015987.1 expression is quantified. Does this perturbation result in a significant change in AC015987.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Determine whether TMEM87B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Determine whether TMEM87B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HMGCS1 expression is quantified. Does this perturbation result in a significant change in HMGCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HMGCS1 expression is quantified. Does this perturbation result in a significant change in HMGCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is quantified. Does this perturbation result in a significant change in DYNC1H1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is quantified. Does this perturbation result in a significant change in DYNC1H1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in H3F3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in H3F3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of USP37. Does perturbing SYVN1 lead to a significant change in USP37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of USP37. Does perturbing SYVN1 lead to a significant change in USP37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in RP11-334C17.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in RP11-334C17.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2358,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor IL13RA1 expression. Decide whether this perturbation leads to a significant alteration in IL13RA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor IL13RA1 expression. Decide whether this perturbation leads to a significant alteration in IL13RA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of RP11-573D15.2. Does this perturbation cause a significant change in RP11-573D15.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of RP11-573D15.2. Does this perturbation cause a significant change in RP11-573D15.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in CRNDE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in CRNDE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1280,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Determine whether TFPI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Determine whether TFPI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ATXN7L3B expression is quantified. Does this perturbation result in a significant change in ATXN7L3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ATXN7L3B expression is quantified. Does this perturbation result in a significant change in ATXN7L3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ZNF678 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ZNF678 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of CDCA3. Does perturbing UFM1 lead to a significant change in CDCA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of CDCA3. Does perturbing UFM1 lead to a significant change in CDCA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3223,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ZNF789 expression is observed. Does this perturbation lead to a significant difference in ZNF789 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ZNF789 expression is observed. Does this perturbation lead to a significant difference in ZNF789 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and KCNH7 expression is measured. Determine whether KCNH7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and KCNH7 expression is measured. Determine whether KCNH7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of PTGS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of PTGS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1293,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and RP11-573D15.9 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and RP11-573D15.9 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4368,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor USP34 expression. Decide whether this perturbation leads to a significant alteration in USP34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor USP34 expression. Decide whether this perturbation leads to a significant alteration in USP34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ANKRD10. Does perturbing SRPRB lead to a significant change in ANKRD10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ANKRD10. Does perturbing SRPRB lead to a significant change in ANKRD10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2183,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-838N2.4. Does this perturbation cause a significant change in RP11-838N2.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-838N2.4. Does this perturbation cause a significant change in RP11-838N2.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1638,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor DNASE2 expression. Decide whether this perturbation leads to a significant alteration in DNASE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor DNASE2 expression. Decide whether this perturbation leads to a significant alteration in DNASE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and AC005540.3 expression is quantified. Does this perturbation result in a significant change in AC005540.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and AC005540.3 expression is quantified. Does this perturbation result in a significant change in AC005540.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MLEC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MLEC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in RP11-61E11.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in RP11-61E11.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4038,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor NTRK1 expression. Decide whether this perturbation leads to a significant alteration in NTRK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor NTRK1 expression. Decide whether this perturbation leads to a significant alteration in NTRK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and FAM114A1 expression is quantified. Does this perturbation result in a significant change in FAM114A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and FAM114A1 expression is quantified. Does this perturbation result in a significant change in FAM114A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and NAV1 expression is measured. Determine whether NAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and NAV1 expression is measured. Determine whether NAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4383,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and GALNT7 expression is observed. Does this perturbation lead to a significant difference in GALNT7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and GALNT7 expression is observed. Does this perturbation lead to a significant difference in GALNT7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ADAMTS10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ADAMTS10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RP11-685N10.1. Does this perturbation cause a significant change in RP11-685N10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RP11-685N10.1. Does this perturbation cause a significant change in RP11-685N10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4058,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP11-15E18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-15E18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP11-15E18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-15E18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
703,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and UQCRB expression is observed. Does this perturbation lead to a significant difference in UQCRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and UQCRB expression is observed. Does this perturbation lead to a significant difference in UQCRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of OR2T6. Does perturbing GMPPB lead to a significant change in OR2T6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of OR2T6. Does perturbing GMPPB lead to a significant change in OR2T6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in RP11-242O24.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in RP11-242O24.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PELO. Does perturbing SLC39A7 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PELO. Does perturbing SLC39A7 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of SHOX2. Does this perturbation cause a significant change in SHOX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of SHOX2. Does this perturbation cause a significant change in SHOX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Determine whether ARHGAP30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Determine whether ARHGAP30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Determine whether SOBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Determine whether SOBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and TAP1 expression is measured. Determine whether TAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and TAP1 expression is measured. Determine whether TAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2770,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1473,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ARHGAP30 expression is observed. Does this perturbation lead to a significant difference in ARHGAP30 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ARHGAP30 expression is observed. Does this perturbation lead to a significant difference in ARHGAP30 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in POLR2J3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in POLR2J3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3263,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and HLA-E expression is observed. Does this perturbation lead to a significant difference in HLA-E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and HLA-E expression is observed. Does this perturbation lead to a significant difference in HLA-E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-640M9.1. Does perturbing SOCS1 lead to a significant change in RP11-640M9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-640M9.1. Does perturbing SOCS1 lead to a significant change in RP11-640M9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PPP1R16B. Does perturbing YIPF5 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PPP1R16B. Does perturbing YIPF5 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3430,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Does this perturbation cause a significant change in ARHGAP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Does this perturbation cause a significant change in ARHGAP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is measured. Determine whether RP11-445H22.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is measured. Determine whether RP11-445H22.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2678,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CTSV expression. Decide whether this perturbation leads to a significant alteration in CTSV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CTSV expression. Decide whether this perturbation leads to a significant alteration in CTSV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and HM13 expression is measured. Determine whether HM13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and HM13 expression is measured. Determine whether HM13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1630,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Does this perturbation cause a significant change in DNASE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Does this perturbation cause a significant change in DNASE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3570,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Does this perturbation cause a significant change in APOBEC3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Does this perturbation cause a significant change in APOBEC3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PDE9A expression is measured. Determine whether PDE9A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PDE9A expression is measured. Determine whether PDE9A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of C12orf23. Does this perturbation cause a significant change in C12orf23 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of C12orf23. Does this perturbation cause a significant change in C12orf23 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and APOL4 expression is measured. Determine whether APOL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and APOL4 expression is measured. Determine whether APOL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TKTL1 expression is quantified. Does this perturbation result in a significant change in TKTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TKTL1 expression is quantified. Does this perturbation result in a significant change in TKTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and PITPNB expression is quantified. Does this perturbation result in a significant change in PITPNB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and PITPNB expression is quantified. Does this perturbation result in a significant change in PITPNB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
363,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and DOCK11 expression is observed. Does this perturbation lead to a significant difference in DOCK11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and DOCK11 expression is observed. Does this perturbation lead to a significant difference in DOCK11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2958,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ATP5EP2 expression. Decide whether this perturbation leads to a significant alteration in ATP5EP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ATP5EP2 expression. Decide whether this perturbation leads to a significant alteration in ATP5EP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Determine whether NBEAL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Determine whether NBEAL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Determine whether DOCK8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Determine whether DOCK8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3550,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Does this perturbation cause a significant change in CCRL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Does this perturbation cause a significant change in CCRL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and ZNF789 expression is measured. Determine whether ZNF789 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and ZNF789 expression is measured. Determine whether ZNF789 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RP11-685N10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RP11-685N10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4903,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CHD3 expression is observed. Does this perturbation lead to a significant difference in CHD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CHD3 expression is observed. Does this perturbation lead to a significant difference in CHD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in LDLR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in LDLR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and DDIT4 expression is quantified. Does this perturbation result in a significant change in DDIT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and DDIT4 expression is quantified. Does this perturbation result in a significant change in DDIT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and VAMP2 expression is measured. Determine whether VAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and VAMP2 expression is measured. Determine whether VAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3158,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor SLC25A35 expression. Decide whether this perturbation leads to a significant alteration in SLC25A35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor SLC25A35 expression. Decide whether this perturbation leads to a significant alteration in SLC25A35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2780,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of AKAP11. Does perturbing TMEM167A lead to a significant change in AKAP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of AKAP11. Does perturbing TMEM167A lead to a significant change in AKAP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ANXA4 expression is quantified. Does this perturbation result in a significant change in ANXA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ANXA4 expression is quantified. Does this perturbation result in a significant change in ANXA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ANPEP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ANPEP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is measured. Determine whether RP11-90P5.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is measured. Determine whether RP11-90P5.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1343,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NSD1 expression is observed. Does this perturbation lead to a significant difference in NSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NSD1 expression is observed. Does this perturbation lead to a significant difference in NSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
51,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of C6orf48. Does perturbing CREB1 lead to a significant change in C6orf48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of C6orf48. Does perturbing CREB1 lead to a significant change in C6orf48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and PPP4R2 expression is quantified. Does this perturbation result in a significant change in PPP4R2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and PPP4R2 expression is quantified. Does this perturbation result in a significant change in PPP4R2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RIMS3 expression is measured. Determine whether RIMS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RIMS3 expression is measured. Determine whether RIMS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of PSORS1C1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of PSORS1C1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4123,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and FOXO6 expression is observed. Does this perturbation lead to a significant difference in FOXO6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and FOXO6 expression is observed. Does this perturbation lead to a significant difference in FOXO6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PAXBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PAXBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in DSC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in DSC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and AC079466.1 expression is quantified. Does this perturbation result in a significant change in AC079466.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and AC079466.1 expression is quantified. Does this perturbation result in a significant change in AC079466.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and KIF4A expression is measured. Determine whether KIF4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and KIF4A expression is measured. Determine whether KIF4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3798,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor POLR2J3 expression. Decide whether this perturbation leads to a significant alteration in POLR2J3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor POLR2J3 expression. Decide whether this perturbation leads to a significant alteration in POLR2J3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2308,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1228,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor UBE3A expression. Decide whether this perturbation leads to a significant alteration in UBE3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor UBE3A expression. Decide whether this perturbation leads to a significant alteration in UBE3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1418,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NOXA1 expression. Decide whether this perturbation leads to a significant alteration in NOXA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NOXA1 expression. Decide whether this perturbation leads to a significant alteration in NOXA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of TTC18. Does perturbing TIMM44 lead to a significant change in TTC18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of TTC18. Does perturbing TIMM44 lead to a significant change in TTC18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ABI2. Does this perturbation cause a significant change in ABI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ABI2. Does this perturbation cause a significant change in ABI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CLINT1. Does perturbing SRPR lead to a significant change in CLINT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CLINT1. Does perturbing SRPR lead to a significant change in CLINT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Determine whether HERC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Determine whether HERC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Determine whether APOBEC3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Determine whether APOBEC3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2520,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Does this perturbation cause a significant change in RNF139-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Does this perturbation cause a significant change in RNF139-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
273,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DUT expression is observed. Does this perturbation lead to a significant difference in DUT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DUT expression is observed. Does this perturbation lead to a significant difference in DUT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of UHRF1BP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of UHRF1BP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3803,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TSPAN33. Does this perturbation cause a significant change in TSPAN33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TSPAN33. Does this perturbation cause a significant change in TSPAN33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of RPL39. Does perturbing MTHFD1 lead to a significant change in RPL39 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of RPL39. Does perturbing MTHFD1 lead to a significant change in RPL39 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ZXDA expression is quantified. Does this perturbation result in a significant change in ZXDA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ZXDA expression is quantified. Does this perturbation result in a significant change in ZXDA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP11-15E18.1. Does perturbing CCND3 lead to a significant change in RP11-15E18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP11-15E18.1. Does perturbing CCND3 lead to a significant change in RP11-15E18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and TRAPPC10 expression is measured. Determine whether TRAPPC10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and TRAPPC10 expression is measured. Determine whether TRAPPC10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1248,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor CYP17A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in CYP17A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor CYP17A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in CYP17A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
140,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Does this perturbation cause a significant change in RDH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Does this perturbation cause a significant change in RDH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1180,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Does this perturbation cause a significant change in SETD5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Does this perturbation cause a significant change in SETD5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in DNTTIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in DNTTIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1818,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor NFAT5 expression. Decide whether this perturbation leads to a significant alteration in NFAT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor NFAT5 expression. Decide whether this perturbation leads to a significant alteration in NFAT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of FCGRT. Does this perturbation cause a significant change in FCGRT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of FCGRT. Does this perturbation cause a significant change in FCGRT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in PIK3R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in PIK3R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2960,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Does this perturbation cause a significant change in CPQ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Does this perturbation cause a significant change in CPQ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and PTGS1 expression is measured. Determine whether PTGS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and PTGS1 expression is measured. Determine whether PTGS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA1432 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA1432 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Determine whether ZEB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Determine whether ZEB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is quantified. Does this perturbation result in a significant change in RP11-381O7.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is quantified. Does this perturbation result in a significant change in RP11-381O7.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of LRIF1. Does perturbing MRGBP lead to a significant change in LRIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of LRIF1. Does perturbing MRGBP lead to a significant change in LRIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
64,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RIOK3. Does this perturbation cause a significant change in RIOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RIOK3. Does this perturbation cause a significant change in RIOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of USP34. Does perturbing SRPRB lead to a significant change in USP34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of USP34. Does perturbing SRPRB lead to a significant change in USP34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and UQCRB expression is quantified. Does this perturbation result in a significant change in UQCRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and UQCRB expression is quantified. Does this perturbation result in a significant change in UQCRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and RP11-146D12.2 expression is measured. Determine whether RP11-146D12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and RP11-146D12.2 expression is measured. Determine whether RP11-146D12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
743,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ANXA4 expression is observed. Does this perturbation lead to a significant difference in ANXA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ANXA4 expression is observed. Does this perturbation lead to a significant difference in ANXA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4540,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ROCK1 expression is quantified. Does this perturbation result in a significant change in ROCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ROCK1 expression is quantified. Does this perturbation result in a significant change in ROCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1893,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and RP11-434H6.6 expression is observed. Does this perturbation lead to a significant difference in RP11-434H6.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and RP11-434H6.6 expression is observed. Does this perturbation lead to a significant difference in RP11-434H6.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
523,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and DDX6 expression is observed. Does this perturbation lead to a significant difference in DDX6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and DDX6 expression is observed. Does this perturbation lead to a significant difference in DDX6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of RP11-3D4.3. Does this perturbation cause a significant change in RP11-3D4.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of RP11-3D4.3. Does this perturbation cause a significant change in RP11-3D4.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of USP34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of USP34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is measured. Determine whether CTC-550B14.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is measured. Determine whether CTC-550B14.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
58,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor C6orf48 expression. Decide whether this perturbation leads to a significant alteration in C6orf48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor C6orf48 expression. Decide whether this perturbation leads to a significant alteration in C6orf48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of EBI3. Does perturbing ATP5B lead to a significant change in EBI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of EBI3. Does perturbing ATP5B lead to a significant change in EBI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and SRP72 expression is measured. Determine whether SRP72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and SRP72 expression is measured. Determine whether SRP72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CD83 expression is quantified. Does this perturbation result in a significant change in CD83 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CD83 expression is quantified. Does this perturbation result in a significant change in CD83 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2270,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Does this perturbation cause a significant change in PSORS1C1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Does this perturbation cause a significant change in PSORS1C1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CST7. Does perturbing DERL2 lead to a significant change in CST7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CST7. Does perturbing DERL2 lead to a significant change in CST7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SP100 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SP100 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
738,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor BRWD3 expression. Decide whether this perturbation leads to a significant alteration in BRWD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor BRWD3 expression. Decide whether this perturbation leads to a significant alteration in BRWD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and UHRF1BP1L expression is measured. Determine whether UHRF1BP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and UHRF1BP1L expression is measured. Determine whether UHRF1BP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of AC104532.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of AC104532.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1823,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and DDIT4 expression is observed. Does this perturbation lead to a significant difference in DDIT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and DDIT4 expression is observed. Does this perturbation lead to a significant difference in DDIT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
943,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-789C1.1 expression is observed. Does this perturbation lead to a significant difference in RP11-789C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-789C1.1 expression is observed. Does this perturbation lead to a significant difference in RP11-789C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2438,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP13-216E22.4 expression. Decide whether this perturbation leads to a significant alteration in RP13-216E22.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP13-216E22.4 expression. Decide whether this perturbation leads to a significant alteration in RP13-216E22.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1968,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TRIM24. Does perturbing TTI1 lead to a significant change in TRIM24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TRIM24. Does perturbing TTI1 lead to a significant change in TRIM24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of CDRT4. Does perturbing OST4 lead to a significant change in CDRT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of CDRT4. Does perturbing OST4 lead to a significant change in CDRT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1110,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Does this perturbation cause a significant change in GOT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Does this perturbation cause a significant change in GOT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Determine whether AC015987.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Determine whether AC015987.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4013,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and DNMBP expression is observed. Does this perturbation lead to a significant difference in DNMBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and DNMBP expression is observed. Does this perturbation lead to a significant difference in DNMBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and CTNNB1 expression is measured. Determine whether CTNNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and CTNNB1 expression is measured. Determine whether CTNNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in CYP17A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in CYP17A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of TGOLN2. Does perturbing SPCS3 lead to a significant change in TGOLN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of TGOLN2. Does perturbing SPCS3 lead to a significant change in TGOLN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1003,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and RP11-334C17.5 expression is observed. Does this perturbation lead to a significant difference in RP11-334C17.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and RP11-334C17.5 expression is observed. Does this perturbation lead to a significant difference in RP11-334C17.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDK13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDK13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1073,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and ADAMTS10 expression is observed. Does this perturbation lead to a significant difference in ADAMTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and ADAMTS10 expression is observed. Does this perturbation lead to a significant difference in ADAMTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EPS15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EPS15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RP11-685N10.1. Does perturbing MARS lead to a significant change in RP11-685N10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RP11-685N10.1. Does perturbing MARS lead to a significant change in RP11-685N10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3453,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ZFP36L2 expression is observed. Does this perturbation lead to a significant difference in ZFP36L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ZFP36L2 expression is observed. Does this perturbation lead to a significant difference in ZFP36L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is measured. Determine whether RP11-381O7.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is measured. Determine whether RP11-381O7.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and CENPF expression is measured. Determine whether CENPF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and CENPF expression is measured. Determine whether CENPF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of HLA-E. Does this perturbation cause a significant change in HLA-E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of HLA-E. Does this perturbation cause a significant change in HLA-E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2618,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ZEB1. Does perturbing SAMM50 lead to a significant change in ZEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ZEB1. Does perturbing SAMM50 lead to a significant change in ZEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1770,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Does this perturbation cause a significant change in SDF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Does this perturbation cause a significant change in SDF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TRPM4. Does this perturbation cause a significant change in TRPM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TRPM4. Does this perturbation cause a significant change in TRPM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of PARP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of PARP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of CDCA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of CDCA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
383,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Determine whether RP11-138C9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Determine whether RP11-138C9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of TAP1. Does perturbing SEC61G lead to a significant change in TAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of TAP1. Does perturbing SEC61G lead to a significant change in TAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is measured. Determine whether DKFZP779L1853 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is measured. Determine whether DKFZP779L1853 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and BIRC5 expression is quantified. Does this perturbation result in a significant change in BIRC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and BIRC5 expression is quantified. Does this perturbation result in a significant change in BIRC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is quantified. Does this perturbation result in a significant change in RBM12B-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is quantified. Does this perturbation result in a significant change in RBM12B-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in NBEAL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in NBEAL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
418,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor SPINK5 expression. Decide whether this perturbation leads to a significant alteration in SPINK5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor SPINK5 expression. Decide whether this perturbation leads to a significant alteration in SPINK5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Determine whether ANKRD10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Determine whether ANKRD10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4833,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and RP11-390B4.5 expression is observed. Does this perturbation lead to a significant difference in RP11-390B4.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and RP11-390B4.5 expression is observed. Does this perturbation lead to a significant difference in RP11-390B4.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of H3F3B. Does this perturbation cause a significant change in H3F3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of H3F3B. Does this perturbation cause a significant change in H3F3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ARHGAP11A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ARHGAP11A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1493,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RP11-24F11.2 expression is observed. Does this perturbation lead to a significant difference in RP11-24F11.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RP11-24F11.2 expression is observed. Does this perturbation lead to a significant difference in RP11-24F11.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of OBSCN. Does perturbing HYOU1 lead to a significant change in OBSCN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of OBSCN. Does perturbing HYOU1 lead to a significant change in OBSCN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of UHMK1. Does this perturbation cause a significant change in UHMK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of UHMK1. Does this perturbation cause a significant change in UHMK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of RP11-423O2.5. Does this perturbation cause a significant change in RP11-423O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of RP11-423O2.5. Does this perturbation cause a significant change in RP11-423O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3153,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and SLC25A35 expression is observed. Does this perturbation lead to a significant difference in SLC25A35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and SLC25A35 expression is observed. Does this perturbation lead to a significant difference in SLC25A35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and IL13RA1 expression is measured. Determine whether IL13RA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and IL13RA1 expression is measured. Determine whether IL13RA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of MEX3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of MEX3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and STC2 expression is measured. Determine whether STC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and STC2 expression is measured. Determine whether STC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of DOCK8. Does this perturbation cause a significant change in DOCK8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of DOCK8. Does this perturbation cause a significant change in DOCK8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of UQCRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of UQCRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4648,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDKN2C expression is quantified. Does this perturbation result in a significant change in CDKN2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDKN2C expression is quantified. Does this perturbation result in a significant change in CDKN2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of PCK2. Does perturbing EIF2B2 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of PCK2. Does perturbing EIF2B2 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Determine whether PGM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Determine whether PGM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-640M9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-640M9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and KCNJ13 expression is measured. Determine whether KCNJ13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and KCNJ13 expression is measured. Determine whether KCNJ13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4638,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor BOLA3 expression. Decide whether this perturbation leads to a significant alteration in BOLA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor BOLA3 expression. Decide whether this perturbation leads to a significant alteration in BOLA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of CTD-2001C12.1. Does perturbing YIPF5 lead to a significant change in CTD-2001C12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of CTD-2001C12.1. Does perturbing YIPF5 lead to a significant change in CTD-2001C12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TKTL1. Does this perturbation cause a significant change in TKTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TKTL1. Does this perturbation cause a significant change in TKTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of HLTF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of HLTF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AFF1 expression is quantified. Does this perturbation result in a significant change in AFF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AFF1 expression is quantified. Does this perturbation result in a significant change in AFF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3958,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor SERPINF2 expression. Decide whether this perturbation leads to a significant alteration in SERPINF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor SERPINF2 expression. Decide whether this perturbation leads to a significant alteration in SERPINF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MT2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MT2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and C6orf120 expression is measured. Determine whether C6orf120 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and C6orf120 expression is measured. Determine whether C6orf120 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SNRNP25 expression is measured. Determine whether SNRNP25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SNRNP25 expression is measured. Determine whether SNRNP25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3730,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Does this perturbation cause a significant change in PITPNB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Does this perturbation cause a significant change in PITPNB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4273,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and IDS expression is observed. Does this perturbation lead to a significant difference in IDS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and IDS expression is observed. Does this perturbation lead to a significant difference in IDS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ANXA4. Does this perturbation cause a significant change in ANXA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ANXA4. Does this perturbation cause a significant change in ANXA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AMOTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AMOTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of KLF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of KLF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1870,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Does this perturbation cause a significant change in AC096559.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Does this perturbation cause a significant change in AC096559.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is measured. Determine whether RP11-212I21.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is measured. Determine whether RP11-212I21.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ANKRD11 expression is quantified. Does this perturbation result in a significant change in ANKRD11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ANKRD11 expression is quantified. Does this perturbation result in a significant change in ANKRD11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in NINJ2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in NINJ2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and H1FX expression is quantified. Does this perturbation result in a significant change in H1FX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and H1FX expression is quantified. Does this perturbation result in a significant change in H1FX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of RP11-573D15.2. Does perturbing DDOST lead to a significant change in RP11-573D15.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of RP11-573D15.2. Does perturbing DDOST lead to a significant change in RP11-573D15.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4863,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and NAV2 expression is observed. Does this perturbation lead to a significant difference in NAV2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and NAV2 expression is observed. Does this perturbation lead to a significant difference in NAV2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of HPCAL1. Does perturbing ASCC3 lead to a significant change in HPCAL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of HPCAL1. Does perturbing ASCC3 lead to a significant change in HPCAL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
253,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and LINC00657 expression is observed. Does this perturbation lead to a significant difference in LINC00657 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and LINC00657 expression is observed. Does this perturbation lead to a significant difference in LINC00657 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ERV3-1. Does perturbing SRPR lead to a significant change in ERV3-1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ERV3-1. Does perturbing SRPR lead to a significant change in ERV3-1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of CFH. Does perturbing SPCS3 lead to a significant change in CFH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of CFH. Does perturbing SPCS3 lead to a significant change in CFH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and PPM1N expression is measured. Determine whether PPM1N exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and PPM1N expression is measured. Determine whether PPM1N exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1480,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Does this perturbation cause a significant change in WHSC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Does this perturbation cause a significant change in WHSC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
76,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Determine whether CEBPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Determine whether CEBPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3293,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and GS1-166A23.1 expression is observed. Does this perturbation lead to a significant difference in GS1-166A23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and GS1-166A23.1 expression is observed. Does this perturbation lead to a significant difference in GS1-166A23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RP11-685N10.1 expression is measured. Determine whether RP11-685N10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RP11-685N10.1 expression is measured. Determine whether RP11-685N10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Determine whether APOL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Determine whether APOL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ARSA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ARSA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and BIRC5 expression is measured. Determine whether BIRC5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and BIRC5 expression is measured. Determine whether BIRC5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC096559.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC096559.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3978,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor SEC23IP expression. Decide whether this perturbation leads to a significant alteration in SEC23IP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor SEC23IP expression. Decide whether this perturbation leads to a significant alteration in SEC23IP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1948,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GLG1 expression. Decide whether this perturbation leads to a significant alteration in GLG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GLG1 expression. Decide whether this perturbation leads to a significant alteration in GLG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
6,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Determine whether ZNF429 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Determine whether ZNF429 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and BOLA3 expression is quantified. Does this perturbation result in a significant change in BOLA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and BOLA3 expression is quantified. Does this perturbation result in a significant change in BOLA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ZNF678. Does this perturbation cause a significant change in ZNF678 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ZNF678. Does this perturbation cause a significant change in ZNF678 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
323,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4630,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Does this perturbation cause a significant change in BOLA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Does this perturbation cause a significant change in BOLA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SNRNP25. Does perturbing SLC39A7 lead to a significant change in SNRNP25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SNRNP25. Does perturbing SLC39A7 lead to a significant change in SNRNP25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Determine whether IL13RA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Determine whether IL13RA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in HLA-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in HLA-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4133,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and WDR72 expression is observed. Does this perturbation lead to a significant difference in WDR72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and WDR72 expression is observed. Does this perturbation lead to a significant difference in WDR72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TRPM4 expression is measured. Determine whether TRPM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TRPM4 expression is measured. Determine whether TRPM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Determine whether EP400 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Determine whether EP400 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4113,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and CDCA3 expression is observed. Does this perturbation lead to a significant difference in CDCA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and CDCA3 expression is observed. Does this perturbation lead to a significant difference in CDCA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Determine whether ROCK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Determine whether ROCK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."