,question,answer,question_new 123611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of SELENOM. Does perturbing CCT5 lead to a significant change in SELENOM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of SELENOM. Does perturbing CCT5 lead to a significant change in SELENOM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 105191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1F and examine the expression of ZNF32. Does perturbing ATP6V1F lead to a significant change in ZNF32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1F and examine the expression of ZNF32. Does perturbing ATP6V1F lead to a significant change in ZNF32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 67017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNLRB1, does the expression profile of SLC6A6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNLRB1, does the expression profile of SLC6A6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 103008,"You are a functional genomics specialist. In K562 cells, we perturb RNGTT and monitor RNF6 expression. Decide whether this perturbation leads to a significant alteration in RNF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RNGTT and monitor RNF6 expression. Decide whether this perturbation leads to a significant alteration in RNF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 73483,You are an expert in regulatory genomics. Consider data from K562 cells in which CAP1 is perturbed and INPP1 expression is observed. Does this perturbation lead to a significant difference in INPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CAP1 is perturbed and INPP1 expression is observed. Does this perturbation lead to a significant difference in INPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 29505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C9orf78 is associated with a significant change in ARL6IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C9orf78 is associated with a significant change in ARL6IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 118743,You are an expert in regulatory genomics. Consider data from K562 cells in which CYREN is perturbed and HELZ expression is observed. Does this perturbation lead to a significant difference in HELZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CYREN is perturbed and HELZ expression is observed. Does this perturbation lead to a significant difference in HELZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 72151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARFRP1 and examine the expression of SSNA1. Does perturbing ARFRP1 lead to a significant change in SSNA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARFRP1 and examine the expression of SSNA1. Does perturbing ARFRP1 lead to a significant change in SSNA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 110505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM10 is associated with a significant change in REPS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM10 is associated with a significant change in REPS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 68843,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL28 is perturbed and MRPL50 expression is observed. Does this perturbation lead to a significant difference in MRPL50 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL28 is perturbed and MRPL50 expression is observed. Does this perturbation lead to a significant difference in MRPL50 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 100809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC1 is perturbed and B4GALT1 expression is measured. Determine whether B4GALT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC1 is perturbed and B4GALT1 expression is measured. Determine whether B4GALT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 77453,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP9 is perturbed and THBD expression is observed. Does this perturbation lead to a significant difference in THBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP9 is perturbed and THBD expression is observed. Does this perturbation lead to a significant difference in THBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 79889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC4 is perturbed and BID expression is measured. Determine whether BID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC4 is perturbed and BID expression is measured. Determine whether BID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 64738,"You are a functional genomics specialist. In K562 cells, we perturb PYURF and monitor GADD45A expression. Decide whether this perturbation leads to a significant alteration in GADD45A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PYURF and monitor GADD45A expression. Decide whether this perturbation leads to a significant alteration in GADD45A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 93373,You are an expert in regulatory genomics. Consider data from K562 cells in which TTF2 is perturbed and FAS expression is observed. Does this perturbation lead to a significant difference in FAS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTF2 is perturbed and FAS expression is observed. Does this perturbation lead to a significant difference in FAS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 85640,"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM5 is perturbed and the expression of ARSK is measured. Does this perturbation cause a significant change in ARSK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM5 is perturbed and the expression of ARSK is measured. Does this perturbation cause a significant change in ARSK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC6 is associated with a significant change in SHISA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC6 is associated with a significant change in SHISA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 93909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRD8 is perturbed and OS9 expression is measured. Determine whether OS9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRD8 is perturbed and OS9 expression is measured. Determine whether OS9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 45505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX23 is associated with a significant change in PPM1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX23 is associated with a significant change in PPM1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 58170,"You are an expert in single-cell biology and functional genomics. In K562 cells, MKRN1 is perturbed and the expression of PCDH7 is measured. Does this perturbation cause a significant change in PCDH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MKRN1 is perturbed and the expression of PCDH7 is measured. Does this perturbation cause a significant change in PCDH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 23164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHC1 and then measure expression of ZNF205. Does this perturbation cause a significant change in ZNF205 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHC1 and then measure expression of ZNF205. Does this perturbation cause a significant change in ZNF205 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 54275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TOE1 is associated with a significant change in NIPAL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TOE1 is associated with a significant change in NIPAL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 86748,"You are a functional genomics specialist. In K562 cells, we perturb EEFSEC and monitor NREP expression. Decide whether this perturbation leads to a significant alteration in NREP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EEFSEC and monitor NREP expression. Decide whether this perturbation leads to a significant alteration in NREP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 64923,You are an expert in regulatory genomics. Consider data from K562 cells in which GON4L is perturbed and SELENOM expression is observed. Does this perturbation lead to a significant difference in SELENOM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GON4L is perturbed and SELENOM expression is observed. Does this perturbation lead to a significant difference in SELENOM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 69121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEF1A1 and examine the expression of PDXDC1. Does perturbing EEF1A1 lead to a significant change in PDXDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEF1A1 and examine the expression of PDXDC1. Does perturbing EEF1A1 lead to a significant change in PDXDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1158,"You are a functional genomics specialist. In K562 cells, we perturb FBXO42 and monitor TNNT1 expression. Decide whether this perturbation leads to a significant alteration in TNNT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FBXO42 and monitor TNNT1 expression. Decide whether this perturbation leads to a significant alteration in TNNT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 120953,You are an expert in regulatory genomics. Consider data from K562 cells in which SLBP is perturbed and MYL9 expression is observed. Does this perturbation lead to a significant difference in MYL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLBP is perturbed and MYL9 expression is observed. Does this perturbation lead to a significant difference in MYL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 53790,"You are an expert in single-cell biology and functional genomics. In K562 cells, GTPBP4 is perturbed and the expression of HEXA is measured. Does this perturbation cause a significant change in HEXA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GTPBP4 is perturbed and the expression of HEXA is measured. Does this perturbation cause a significant change in HEXA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 116469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDCD11 is perturbed and MIEN1 expression is measured. Determine whether MIEN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDCD11 is perturbed and MIEN1 expression is measured. Determine whether MIEN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFAM is perturbed and the expression of MYH9 is measured. Determine whether MYH9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFAM is perturbed and the expression of MYH9 is measured. Determine whether MYH9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 36083,You are an expert in regulatory genomics. Consider data from K562 cells in which PMF1 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PMF1 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6853,You are an expert in regulatory genomics. Consider data from K562 cells in which PDCD6 is perturbed and GSPT2 expression is observed. Does this perturbation lead to a significant difference in GSPT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PDCD6 is perturbed and GSPT2 expression is observed. Does this perturbation lead to a significant difference in GSPT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 85412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASF1B is perturbed and RCAN1 expression is quantified. Does this perturbation result in a significant change in RCAN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASF1B is perturbed and RCAN1 expression is quantified. Does this perturbation result in a significant change in RCAN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 111634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UTP18 and then measure expression of BORCS5. Does this perturbation cause a significant change in BORCS5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UTP18 and then measure expression of BORCS5. Does this perturbation cause a significant change in BORCS5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 82278,"You are a functional genomics specialist. In K562 cells, we perturb PSMG2 and monitor MOSPD1 expression. Decide whether this perturbation leads to a significant alteration in MOSPD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMG2 and monitor MOSPD1 expression. Decide whether this perturbation leads to a significant alteration in MOSPD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5150,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZMAT2 is perturbed and the expression of NEU1 is measured. Does this perturbation cause a significant change in NEU1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZMAT2 is perturbed and the expression of NEU1 is measured. Does this perturbation cause a significant change in NEU1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 73254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3C3 and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3C3 and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 99419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS27 is perturbed and ZIM3 expression is measured. Determine whether ZIM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS27 is perturbed and ZIM3 expression is measured. Determine whether ZIM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 98679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GPN2 is perturbed and TSFM expression is measured. Determine whether TSFM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GPN2 is perturbed and TSFM expression is measured. Determine whether TSFM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H13 and examine the expression of RNF25. Does perturbing ZC3H13 lead to a significant change in RNF25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H13 and examine the expression of RNF25. Does perturbing ZC3H13 lead to a significant change in RNF25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 54502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GAPDH is perturbed and SMIM10L1 expression is quantified. Does this perturbation result in a significant change in SMIM10L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GAPDH is perturbed and SMIM10L1 expression is quantified. Does this perturbation result in a significant change in SMIM10L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 45308,"You are a functional genomics specialist. In K562 cells, we perturb COMTD1 and monitor GPATCH8 expression. Decide whether this perturbation leads to a significant alteration in GPATCH8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COMTD1 and monitor GPATCH8 expression. Decide whether this perturbation leads to a significant alteration in GPATCH8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 44712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EDC4 is perturbed and IKBIP expression is quantified. Does this perturbation result in a significant change in IKBIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EDC4 is perturbed and IKBIP expression is quantified. Does this perturbation result in a significant change in IKBIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 86675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC42 is associated with a significant change in KYAT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC42 is associated with a significant change in KYAT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 72981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNF8 and examine the expression of TRIM73. Does perturbing SNF8 lead to a significant change in TRIM73 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNF8 and examine the expression of TRIM73. Does perturbing SNF8 lead to a significant change in TRIM73 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 29194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP192 and then measure expression of HHIP-AS1. Does this perturbation cause a significant change in HHIP-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP192 and then measure expression of HHIP-AS1. Does this perturbation cause a significant change in HHIP-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 85579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RMI1 is perturbed and UBE3C expression is measured. Determine whether UBE3C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RMI1 is perturbed and UBE3C expression is measured. Determine whether UBE3C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 55401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCNA and examine the expression of ZSCAN26. Does perturbing PCNA lead to a significant change in ZSCAN26 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCNA and examine the expression of ZSCAN26. Does perturbing PCNA lead to a significant change in ZSCAN26 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 34290,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS9 is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS9 is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 11221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC3 and examine the expression of SEZ6L2. Does perturbing THOC3 lead to a significant change in SEZ6L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC3 and examine the expression of SEZ6L2. Does perturbing THOC3 lead to a significant change in SEZ6L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 27150,"You are an expert in single-cell biology and functional genomics. In K562 cells, GIT2 is perturbed and the expression of GSE1 is measured. Does this perturbation cause a significant change in GSE1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GIT2 is perturbed and the expression of GSE1 is measured. Does this perturbation cause a significant change in GSE1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 29078,"You are a functional genomics specialist. In K562 cells, we perturb SON and monitor STX3 expression. Decide whether this perturbation leads to a significant alteration in STX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SON and monitor STX3 expression. Decide whether this perturbation leads to a significant alteration in STX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 55853,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and FARP2 expression is observed. Does this perturbation lead to a significant difference in FARP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and FARP2 expression is observed. Does this perturbation lead to a significant difference in FARP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SETD5 and examine the expression of WNK3. Does perturbing SETD5 lead to a significant change in WNK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SETD5 and examine the expression of WNK3. Does perturbing SETD5 lead to a significant change in WNK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 33828,"You are a functional genomics specialist. In K562 cells, we perturb CACNB3 and monitor SYVN1 expression. Decide whether this perturbation leads to a significant alteration in SYVN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CACNB3 and monitor SYVN1 expression. Decide whether this perturbation leads to a significant alteration in SYVN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 74348,"You are a functional genomics specialist. In K562 cells, we perturb CWC22 and monitor NCBP2AS2 expression. Decide whether this perturbation leads to a significant alteration in NCBP2AS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CWC22 and monitor NCBP2AS2 expression. Decide whether this perturbation leads to a significant alteration in NCBP2AS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 82923,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL18 is perturbed and UBTD1 expression is observed. Does this perturbation lead to a significant difference in UBTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL18 is perturbed and UBTD1 expression is observed. Does this perturbation lead to a significant difference in UBTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 30731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM4 and examine the expression of SERINC2. Does perturbing LSM4 lead to a significant change in SERINC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM4 and examine the expression of SERINC2. Does perturbing LSM4 lead to a significant change in SERINC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 51405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ORC3 is associated with a significant change in SAMD9L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ORC3 is associated with a significant change in SAMD9L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 106648,"You are a functional genomics specialist. In K562 cells, we perturb MRPL51 and monitor SLC6A8 expression. Decide whether this perturbation leads to a significant alteration in SLC6A8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL51 and monitor SLC6A8 expression. Decide whether this perturbation leads to a significant alteration in SLC6A8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 24434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYF2 and then measure expression of IRS2. Does this perturbation cause a significant change in IRS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYF2 and then measure expression of IRS2. Does this perturbation cause a significant change in IRS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GPS1 is perturbed and the expression of BDNF is measured. Determine whether BDNF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GPS1 is perturbed and the expression of BDNF is measured. Determine whether BDNF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 28414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR3K and then measure expression of DNER. Does this perturbation cause a significant change in DNER expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR3K and then measure expression of DNER. Does this perturbation cause a significant change in DNER expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 99891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2B and examine the expression of EFEMP1. Does perturbing GTF2B lead to a significant change in EFEMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2B and examine the expression of EFEMP1. Does perturbing GTF2B lead to a significant change in EFEMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 94296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DYNLL1 is perturbed and the expression of ZGPAT is measured. Determine whether ZGPAT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DYNLL1 is perturbed and the expression of ZGPAT is measured. Determine whether ZGPAT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MPG and then measure expression of DLD. Does this perturbation cause a significant change in DLD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MPG and then measure expression of DLD. Does this perturbation cause a significant change in DLD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 63182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMNDC1 is perturbed and SCNM1 expression is quantified. Does this perturbation result in a significant change in SCNM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMNDC1 is perturbed and SCNM1 expression is quantified. Does this perturbation result in a significant change in SCNM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 13084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CMPK1 and then measure expression of GLA. Does this perturbation cause a significant change in GLA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CMPK1 and then measure expression of GLA. Does this perturbation cause a significant change in GLA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 30962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PALB2 is perturbed and TARSL2 expression is quantified. Does this perturbation result in a significant change in TARSL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PALB2 is perturbed and TARSL2 expression is quantified. Does this perturbation result in a significant change in TARSL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6583,You are an expert in regulatory genomics. Consider data from K562 cells in which DCAF6 is perturbed and RPL10A expression is observed. Does this perturbation lead to a significant difference in RPL10A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DCAF6 is perturbed and RPL10A expression is observed. Does this perturbation lead to a significant difference in RPL10A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 63636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPIL4 is perturbed and the expression of SH3RF2 is measured. Determine whether SH3RF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPIL4 is perturbed and the expression of SH3RF2 is measured. Determine whether SH3RF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 26583,You are an expert in regulatory genomics. Consider data from K562 cells in which NARS2 is perturbed and ANKZF1 expression is observed. Does this perturbation lead to a significant difference in ANKZF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NARS2 is perturbed and ANKZF1 expression is observed. Does this perturbation lead to a significant difference in ANKZF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 120582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNTB2 is perturbed and UNC93B1 expression is quantified. Does this perturbation result in a significant change in UNC93B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNTB2 is perturbed and UNC93B1 expression is quantified. Does this perturbation result in a significant change in UNC93B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYBBP1A and examine the expression of F3. Does perturbing MYBBP1A lead to a significant change in F3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYBBP1A and examine the expression of F3. Does perturbing MYBBP1A lead to a significant change in F3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 121326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 14716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP53RK is perturbed and the expression of WIPI1 is measured. Determine whether WIPI1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP53RK is perturbed and the expression of WIPI1 is measured. Determine whether WIPI1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 24631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNRPD3 and examine the expression of WIPI2. Does perturbing SNRPD3 lead to a significant change in WIPI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNRPD3 and examine the expression of WIPI2. Does perturbing SNRPD3 lead to a significant change in WIPI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 86982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GGPS1 is perturbed and ARFGEF2 expression is quantified. Does this perturbation result in a significant change in ARFGEF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GGPS1 is perturbed and ARFGEF2 expression is quantified. Does this perturbation result in a significant change in ARFGEF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 118434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V1C1 and then measure expression of TM7SF2. Does this perturbation cause a significant change in TM7SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V1C1 and then measure expression of TM7SF2. Does this perturbation cause a significant change in TM7SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 115671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC8 and examine the expression of ZNF148. Does perturbing TRAPPC8 lead to a significant change in ZNF148 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC8 and examine the expression of ZNF148. Does perturbing TRAPPC8 lead to a significant change in ZNF148 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 88614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EP400 and then measure expression of ACO2. Does this perturbation cause a significant change in ACO2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EP400 and then measure expression of ACO2. Does this perturbation cause a significant change in ACO2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 67478,"You are a functional genomics specialist. In K562 cells, we perturb MVD and monitor SPTY2D1 expression. Decide whether this perturbation leads to a significant alteration in SPTY2D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MVD and monitor SPTY2D1 expression. Decide whether this perturbation leads to a significant alteration in SPTY2D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 58888,"You are a functional genomics specialist. In K562 cells, we perturb ACTR3 and monitor FBXO9 expression. Decide whether this perturbation leads to a significant alteration in FBXO9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ACTR3 and monitor FBXO9 expression. Decide whether this perturbation leads to a significant alteration in FBXO9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 121183,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMELESS is perturbed and NCBP2 expression is observed. Does this perturbation lead to a significant difference in NCBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMELESS is perturbed and NCBP2 expression is observed. Does this perturbation lead to a significant difference in NCBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 27096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, THAP11 is perturbed and the expression of MEIS2 is measured. Determine whether MEIS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, THAP11 is perturbed and the expression of MEIS2 is measured. Determine whether MEIS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 62498,"You are a functional genomics specialist. In K562 cells, we perturb LAMTOR4 and monitor MCCC1 expression. Decide whether this perturbation leads to a significant alteration in MCCC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb LAMTOR4 and monitor MCCC1 expression. Decide whether this perturbation leads to a significant alteration in MCCC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 29961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NELFB and examine the expression of HLA-B. Does perturbing NELFB lead to a significant change in HLA-B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NELFB and examine the expression of HLA-B. Does perturbing NELFB lead to a significant change in HLA-B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 66297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTR1B, does the expression profile of TMEM132A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTR1B, does the expression profile of TMEM132A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 74088,"You are a functional genomics specialist. In K562 cells, we perturb RBBP5 and monitor TRIM24 expression. Decide whether this perturbation leads to a significant alteration in TRIM24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RBBP5 and monitor TRIM24 expression. Decide whether this perturbation leads to a significant alteration in TRIM24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 79390,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF236 is perturbed and the expression of FILIP1L is measured. Does this perturbation cause a significant change in FILIP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF236 is perturbed and the expression of FILIP1L is measured. Does this perturbation cause a significant change in FILIP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 83855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYRM4 is associated with a significant change in NCAPH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYRM4 is associated with a significant change in NCAPH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 61679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, INTS5 is perturbed and MLLT11 expression is measured. Determine whether MLLT11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, INTS5 is perturbed and MLLT11 expression is measured. Determine whether MLLT11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 36422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EEF2 is perturbed and BTBD1 expression is quantified. Does this perturbation result in a significant change in BTBD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EEF2 is perturbed and BTBD1 expression is quantified. Does this perturbation result in a significant change in BTBD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 8150,"You are an expert in single-cell biology and functional genomics. In K562 cells, SF3A2 is perturbed and the expression of ANKRD50 is measured. Does this perturbation cause a significant change in ANKRD50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SF3A2 is perturbed and the expression of ANKRD50 is measured. Does this perturbation cause a significant change in ANKRD50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 41960,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX3X is perturbed and the expression of TM9SF4 is measured. Does this perturbation cause a significant change in TM9SF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX3X is perturbed and the expression of TM9SF4 is measured. Does this perturbation cause a significant change in TM9SF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAM136A, does the expression profile of EPAS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAM136A, does the expression profile of EPAS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 120403,You are an expert in regulatory genomics. Consider data from K562 cells in which EXOSC9 is perturbed and AEN expression is observed. Does this perturbation lead to a significant difference in AEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EXOSC9 is perturbed and AEN expression is observed. Does this perturbation lead to a significant difference in AEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 20397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of THAP1, does the expression profile of EHBP1L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of THAP1, does the expression profile of EHBP1L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 23645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TM7SF2 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TM7SF2 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 49577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS9, does the expression profile of DIAPH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS9, does the expression profile of DIAPH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 102731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GSPT1 and examine the expression of PDE1C. Does perturbing GSPT1 lead to a significant change in PDE1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GSPT1 and examine the expression of PDE1C. Does perturbing GSPT1 lead to a significant change in PDE1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 120533,You are an expert in regulatory genomics. Consider data from K562 cells in which SNTB2 is perturbed and PIAS4 expression is observed. Does this perturbation lead to a significant difference in PIAS4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SNTB2 is perturbed and PIAS4 expression is observed. Does this perturbation lead to a significant difference in PIAS4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 23581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF3 and examine the expression of MTRR. Does perturbing PRPF3 lead to a significant change in MTRR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF3 and examine the expression of MTRR. Does perturbing PRPF3 lead to a significant change in MTRR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 119327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCT6A, does the expression profile of SLC16A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCT6A, does the expression profile of SLC16A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 50919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and JRK expression is measured. Determine whether JRK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and JRK expression is measured. Determine whether JRK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 23977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS35, does the expression profile of PIP4K2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS35, does the expression profile of PIP4K2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 105599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN23 is perturbed and TRIM16 expression is measured. Determine whether TRIM16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN23 is perturbed and TRIM16 expression is measured. Determine whether TRIM16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 33473,You are an expert in regulatory genomics. Consider data from K562 cells in which HMGCS1 is perturbed and MYL12B expression is observed. Does this perturbation lead to a significant difference in MYL12B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HMGCS1 is perturbed and MYL12B expression is observed. Does this perturbation lead to a significant difference in MYL12B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 94443,You are an expert in regulatory genomics. Consider data from K562 cells in which TLN1 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TLN1 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 42141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BUB3 and examine the expression of MRPL41. Does perturbing BUB3 lead to a significant change in MRPL41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BUB3 and examine the expression of MRPL41. Does perturbing BUB3 lead to a significant change in MRPL41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 24674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDX42 and then measure expression of NUP153. Does this perturbation cause a significant change in NUP153 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDX42 and then measure expression of NUP153. Does this perturbation cause a significant change in NUP153 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 28248,"You are a functional genomics specialist. In K562 cells, we perturb SDHAF2 and monitor NUDT16L1 expression. Decide whether this perturbation leads to a significant alteration in NUDT16L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SDHAF2 and monitor NUDT16L1 expression. Decide whether this perturbation leads to a significant alteration in NUDT16L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 92139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF1B is perturbed and NUDT14 expression is measured. Determine whether NUDT14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF1B is perturbed and NUDT14 expression is measured. Determine whether NUDT14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 38667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF1, does the expression profile of SYS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF1, does the expression profile of SYS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 100849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC1 is perturbed and JTB expression is measured. Determine whether JTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC1 is perturbed and JTB expression is measured. Determine whether JTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 7993,You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFAF3 is perturbed and BCL2L2 expression is observed. Does this perturbation lead to a significant difference in BCL2L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFAF3 is perturbed and BCL2L2 expression is observed. Does this perturbation lead to a significant difference in BCL2L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTBP4 and examine the expression of RALGAPA1. Does perturbing LTBP4 lead to a significant change in RALGAPA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTBP4 and examine the expression of RALGAPA1. Does perturbing LTBP4 lead to a significant change in RALGAPA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 47285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GRSF1 is associated with a significant change in AP1S1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GRSF1 is associated with a significant change in AP1S1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 40207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MSRB1, does the expression profile of CANT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MSRB1, does the expression profile of CANT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 10079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDCD6IP is perturbed and IFT20 expression is measured. Determine whether IFT20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDCD6IP is perturbed and IFT20 expression is measured. Determine whether IFT20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to METTL21A and then measure expression of EMG1. Does this perturbation cause a significant change in EMG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to METTL21A and then measure expression of EMG1. Does this perturbation cause a significant change in EMG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 79782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, USP9X is perturbed and IFT43 expression is quantified. Does this perturbation result in a significant change in IFT43 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, USP9X is perturbed and IFT43 expression is quantified. Does this perturbation result in a significant change in IFT43 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 89002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VMP1 is perturbed and GSK3A expression is quantified. Does this perturbation result in a significant change in GSK3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VMP1 is perturbed and GSK3A expression is quantified. Does this perturbation result in a significant change in GSK3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5633,You are an expert in regulatory genomics. Consider data from K562 cells in which MAT2A is perturbed and NUP43 expression is observed. Does this perturbation lead to a significant difference in NUP43 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAT2A is perturbed and NUP43 expression is observed. Does this perturbation lead to a significant difference in NUP43 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 95472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FGFR1OP is perturbed and ATF4 expression is quantified. Does this perturbation result in a significant change in ATF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FGFR1OP is perturbed and ATF4 expression is quantified. Does this perturbation result in a significant change in ATF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 31209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CTDP1 is perturbed and TBC1D23 expression is measured. Determine whether TBC1D23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CTDP1 is perturbed and TBC1D23 expression is measured. Determine whether TBC1D23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS3, does the expression profile of TRIM8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS3, does the expression profile of TRIM8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 120404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC9 and then measure expression of AEN. Does this perturbation cause a significant change in AEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC9 and then measure expression of AEN. Does this perturbation cause a significant change in AEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 18442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RTCB is perturbed and PRNP expression is quantified. Does this perturbation result in a significant change in PRNP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RTCB is perturbed and PRNP expression is quantified. Does this perturbation result in a significant change in PRNP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FAM136A and then measure expression of SEC31A. Does this perturbation cause a significant change in SEC31A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FAM136A and then measure expression of SEC31A. Does this perturbation cause a significant change in SEC31A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 45247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of BOLA2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of BOLA2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 102571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RNPS1 and examine the expression of ANKRA2. Does perturbing RNPS1 lead to a significant change in ANKRA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RNPS1 and examine the expression of ANKRA2. Does perturbing RNPS1 lead to a significant change in ANKRA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 51766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ALDOA is perturbed and the expression of ITM2C is measured. Determine whether ITM2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ALDOA is perturbed and the expression of ITM2C is measured. Determine whether ITM2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 17895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NPLOC4 is associated with a significant change in CCDC12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NPLOC4 is associated with a significant change in CCDC12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 84116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL22 is perturbed and the expression of PGGT1B is measured. Determine whether PGGT1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL22 is perturbed and the expression of PGGT1B is measured. Determine whether PGGT1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 56676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPA2 is perturbed and the expression of SGK3 is measured. Determine whether SGK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPA2 is perturbed and the expression of SGK3 is measured. Determine whether SGK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 95570,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF2BP2 is perturbed and the expression of SNHG1 is measured. Does this perturbation cause a significant change in SNHG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF2BP2 is perturbed and the expression of SNHG1 is measured. Does this perturbation cause a significant change in SNHG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 90036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FUNDC2 is perturbed and the expression of RECK is measured. Determine whether RECK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FUNDC2 is perturbed and the expression of RECK is measured. Determine whether RECK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 18480,"You are an expert in single-cell biology and functional genomics. In K562 cells, RTCB is perturbed and the expression of AGTPBP1 is measured. Does this perturbation cause a significant change in AGTPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RTCB is perturbed and the expression of AGTPBP1 is measured. Does this perturbation cause a significant change in AGTPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2K is perturbed and SARAF expression is quantified. Does this perturbation result in a significant change in SARAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2K is perturbed and SARAF expression is quantified. Does this perturbation result in a significant change in SARAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 106975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM4 is associated with a significant change in ZNF585A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM4 is associated with a significant change in ZNF585A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 73231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PITRM1 and examine the expression of AASDH. Does perturbing PITRM1 lead to a significant change in AASDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PITRM1 and examine the expression of AASDH. Does perturbing PITRM1 lead to a significant change in AASDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 95608,"You are a functional genomics specialist. In K562 cells, we perturb IRF2BP2 and monitor STMP1 expression. Decide whether this perturbation leads to a significant alteration in STMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IRF2BP2 and monitor STMP1 expression. Decide whether this perturbation leads to a significant alteration in STMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 13841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCAR1 and examine the expression of CNN2. Does perturbing BCAR1 lead to a significant change in CNN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCAR1 and examine the expression of CNN2. Does perturbing BCAR1 lead to a significant change in CNN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 69867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF6, does the expression profile of ANKMY2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF6, does the expression profile of ANKMY2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 103246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of NFU1 is measured. Determine whether NFU1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of NFU1 is measured. Determine whether NFU1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 110001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDT21 and examine the expression of CEBPG. Does perturbing NUDT21 lead to a significant change in CEBPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDT21 and examine the expression of CEBPG. Does perturbing NUDT21 lead to a significant change in CEBPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 64985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP14 is associated with a significant change in GPC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP14 is associated with a significant change in GPC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 87389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CWF19L2 is perturbed and POLR2I expression is measured. Determine whether POLR2I exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CWF19L2 is perturbed and POLR2I expression is measured. Determine whether POLR2I exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 20008,"You are a functional genomics specialist. In K562 cells, we perturb SYS1 and monitor TNFRSF10D expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SYS1 and monitor TNFRSF10D expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 26527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UXS1, does the expression profile of MGRN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UXS1, does the expression profile of MGRN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 28819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SDHA is perturbed and CDK5 expression is measured. Determine whether CDK5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SDHA is perturbed and CDK5 expression is measured. Determine whether CDK5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 71899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCAR1 is perturbed and LRRCC1 expression is measured. Determine whether LRRCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCAR1 is perturbed and LRRCC1 expression is measured. Determine whether LRRCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 15276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RCCD1 is perturbed and the expression of CHIC2 is measured. Determine whether CHIC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RCCD1 is perturbed and the expression of CHIC2 is measured. Determine whether CHIC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 97267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USPL1, does the expression profile of CREB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USPL1, does the expression profile of CREB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 114437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF84, does the expression profile of TPST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF84, does the expression profile of TPST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 14248,"You are a functional genomics specialist. In K562 cells, we perturb MRPL18 and monitor FTSJ3 expression. Decide whether this perturbation leads to a significant alteration in FTSJ3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL18 and monitor FTSJ3 expression. Decide whether this perturbation leads to a significant alteration in FTSJ3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 8471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IST1 and examine the expression of DAZAP2. Does perturbing IST1 lead to a significant change in DAZAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IST1 and examine the expression of DAZAP2. Does perturbing IST1 lead to a significant change in DAZAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 32205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMG3 is associated with a significant change in ZNF496 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMG3 is associated with a significant change in ZNF496 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 17566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTK is perturbed and the expression of STX5 is measured. Determine whether STX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTK is perturbed and the expression of STX5 is measured. Determine whether STX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 115687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRAPPC8, does the expression profile of HSPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRAPPC8, does the expression profile of HSPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 10658,"You are a functional genomics specialist. In K562 cells, we perturb SEC16A and monitor TMEM208 expression. Decide whether this perturbation leads to a significant alteration in TMEM208 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC16A and monitor TMEM208 expression. Decide whether this perturbation leads to a significant alteration in TMEM208 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 32747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MFN2, does the expression profile of G0S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MFN2, does the expression profile of G0S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 34372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LEO1 is perturbed and MRPL41 expression is quantified. Does this perturbation result in a significant change in MRPL41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LEO1 is perturbed and MRPL41 expression is quantified. Does this perturbation result in a significant change in MRPL41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 65205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BET1 is associated with a significant change in UBE2K expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BET1 is associated with a significant change in UBE2K expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 27162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80C is perturbed and NRAS expression is quantified. Does this perturbation result in a significant change in NRAS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80C is perturbed and NRAS expression is quantified. Does this perturbation result in a significant change in NRAS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 85710,"You are an expert in single-cell biology and functional genomics. In K562 cells, CYCS is perturbed and the expression of KRTAP2-3 is measured. Does this perturbation cause a significant change in KRTAP2-3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CYCS is perturbed and the expression of KRTAP2-3 is measured. Does this perturbation cause a significant change in KRTAP2-3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 43775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRNP70 is associated with a significant change in AC016831.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRNP70 is associated with a significant change in AC016831.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 67490,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCS1L is perturbed and the expression of VAMP7 is measured. Does this perturbation cause a significant change in VAMP7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCS1L is perturbed and the expression of VAMP7 is measured. Does this perturbation cause a significant change in VAMP7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 89899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF2 is perturbed and GABARAPL1 expression is measured. Determine whether GABARAPL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF2 is perturbed and GABARAPL1 expression is measured. Determine whether GABARAPL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 43270,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX56 is perturbed and the expression of FANCM is measured. Does this perturbation cause a significant change in FANCM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX56 is perturbed and the expression of FANCM is measured. Does this perturbation cause a significant change in FANCM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 102467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DROSHA, does the expression profile of SLC38A10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DROSHA, does the expression profile of SLC38A10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 14141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RAD51 and examine the expression of DAZAP2. Does perturbing RAD51 lead to a significant change in DAZAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RAD51 and examine the expression of DAZAP2. Does perturbing RAD51 lead to a significant change in DAZAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 12603,You are an expert in regulatory genomics. Consider data from K562 cells in which WBP11 is perturbed and GIT1 expression is observed. Does this perturbation lead to a significant difference in GIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which WBP11 is perturbed and GIT1 expression is observed. Does this perturbation lead to a significant difference in GIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 85063,You are an expert in regulatory genomics. Consider data from K562 cells in which METTL14 is perturbed and PTPRM expression is observed. Does this perturbation lead to a significant difference in PTPRM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which METTL14 is perturbed and PTPRM expression is observed. Does this perturbation lead to a significant difference in PTPRM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 40173,You are an expert in regulatory genomics. Consider data from K562 cells in which TCERG1 is perturbed and LYRM4 expression is observed. Does this perturbation lead to a significant difference in LYRM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TCERG1 is perturbed and LYRM4 expression is observed. Does this perturbation lead to a significant difference in LYRM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 122787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS28, does the expression profile of RTN4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS28, does the expression profile of RTN4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 59652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NPM1 is perturbed and TSPYL4 expression is quantified. Does this perturbation result in a significant change in TSPYL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NPM1 is perturbed and TSPYL4 expression is quantified. Does this perturbation result in a significant change in TSPYL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 89558,"You are a functional genomics specialist. In K562 cells, we perturb PAM16 and monitor LNPEP expression. Decide whether this perturbation leads to a significant alteration in LNPEP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PAM16 and monitor LNPEP expression. Decide whether this perturbation leads to a significant alteration in LNPEP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 88341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BMS1 and examine the expression of PCDH7. Does perturbing BMS1 lead to a significant change in PCDH7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BMS1 and examine the expression of PCDH7. Does perturbing BMS1 lead to a significant change in PCDH7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 8658,"You are a functional genomics specialist. In K562 cells, we perturb VPS25 and monitor PPIH expression. Decide whether this perturbation leads to a significant alteration in PPIH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb VPS25 and monitor PPIH expression. Decide whether this perturbation leads to a significant alteration in PPIH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 35519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RFFL is perturbed and NENF expression is measured. Determine whether NENF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RFFL is perturbed and NENF expression is measured. Determine whether NENF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 58529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPA is perturbed and SAT1 expression is measured. Determine whether SAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPA is perturbed and SAT1 expression is measured. Determine whether SAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 42369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRMT10C is perturbed and SRFBP1 expression is measured. Determine whether SRFBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRMT10C is perturbed and SRFBP1 expression is measured. Determine whether SRFBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 61647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LENG8, does the expression profile of LYPLAL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LENG8, does the expression profile of LYPLAL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 60038,"You are a functional genomics specialist. In K562 cells, we perturb NUF2 and monitor RINT1 expression. Decide whether this perturbation leads to a significant alteration in RINT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NUF2 and monitor RINT1 expression. Decide whether this perturbation leads to a significant alteration in RINT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 64872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD3 is perturbed and GPC1 expression is quantified. Does this perturbation result in a significant change in GPC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD3 is perturbed and GPC1 expression is quantified. Does this perturbation result in a significant change in GPC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 89785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PFN1 is associated with a significant change in C6orf62 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PFN1 is associated with a significant change in C6orf62 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 14767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC27, does the expression profile of ELF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC27, does the expression profile of ELF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 36613,You are an expert in regulatory genomics. Consider data from K562 cells in which DPY19L4 is perturbed and STOM expression is observed. Does this perturbation lead to a significant difference in STOM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DPY19L4 is perturbed and STOM expression is observed. Does this perturbation lead to a significant difference in STOM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 55709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RRS1 is perturbed and ITPR1 expression is measured. Determine whether ITPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RRS1 is perturbed and ITPR1 expression is measured. Determine whether ITPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 121774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SF3B2 and then measure expression of ZNF24. Does this perturbation cause a significant change in ZNF24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SF3B2 and then measure expression of ZNF24. Does this perturbation cause a significant change in ZNF24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 105483,You are an expert in regulatory genomics. Consider data from K562 cells in which RAD51C is perturbed and MED13L expression is observed. Does this perturbation lead to a significant difference in MED13L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RAD51C is perturbed and MED13L expression is observed. Does this perturbation lead to a significant difference in MED13L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 9202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCP110 is perturbed and WASL expression is quantified. Does this perturbation result in a significant change in WASL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCP110 is perturbed and WASL expression is quantified. Does this perturbation result in a significant change in WASL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 34636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP10 is perturbed and the expression of PHLDA3 is measured. Determine whether PHLDA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP10 is perturbed and the expression of PHLDA3 is measured. Determine whether PHLDA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 116685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POT1 is associated with a significant change in DZIP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POT1 is associated with a significant change in DZIP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 7893,You are an expert in regulatory genomics. Consider data from K562 cells in which BRF1 is perturbed and GABPB1-AS1 expression is observed. Does this perturbation lead to a significant difference in GABPB1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BRF1 is perturbed and GABPB1-AS1 expression is observed. Does this perturbation lead to a significant difference in GABPB1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 94882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD11 is perturbed and BIN3 expression is quantified. Does this perturbation result in a significant change in BIN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD11 is perturbed and BIN3 expression is quantified. Does this perturbation result in a significant change in BIN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 27071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THAP11 and examine the expression of HMOX1. Does perturbing THAP11 lead to a significant change in HMOX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THAP11 and examine the expression of HMOX1. Does perturbing THAP11 lead to a significant change in HMOX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 60117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPV3L1, does the expression profile of MT-ND4L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPV3L1, does the expression profile of MT-ND4L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 100745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC23 is associated with a significant change in ELL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC23 is associated with a significant change in ELL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 99314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRNP1 and then measure expression of PARD3. Does this perturbation cause a significant change in PARD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRNP1 and then measure expression of PARD3. Does this perturbation cause a significant change in PARD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 45215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in SRPRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in SRPRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 81646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ALG1 is perturbed and the expression of ABHD2 is measured. Determine whether ABHD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ALG1 is perturbed and the expression of ABHD2 is measured. Determine whether ABHD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCOA4 and then measure expression of STRADA. Does this perturbation cause a significant change in STRADA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCOA4 and then measure expression of STRADA. Does this perturbation cause a significant change in STRADA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 41267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC137, does the expression profile of BHMT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC137, does the expression profile of BHMT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 103960,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUT is perturbed and the expression of GLB1 is measured. Does this perturbation cause a significant change in GLB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUT is perturbed and the expression of GLB1 is measured. Does this perturbation cause a significant change in GLB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 48429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR77 is perturbed and RIDA expression is measured. Determine whether RIDA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR77 is perturbed and RIDA expression is measured. Determine whether RIDA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 116795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TWISTNB is associated with a significant change in TRIM38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TWISTNB is associated with a significant change in TRIM38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 30499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNPC3 is perturbed and MXD4 expression is measured. Determine whether MXD4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNPC3 is perturbed and MXD4 expression is measured. Determine whether MXD4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 89070,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS5 is perturbed and the expression of KLC1 is measured. Does this perturbation cause a significant change in KLC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS5 is perturbed and the expression of KLC1 is measured. Does this perturbation cause a significant change in KLC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 24960,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of TMEM128 is measured. Does this perturbation cause a significant change in TMEM128 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of TMEM128 is measured. Does this perturbation cause a significant change in TMEM128 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 35025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1143 is associated with a significant change in BFAR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1143 is associated with a significant change in BFAR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 90848,"You are a functional genomics specialist. In K562 cells, we perturb SETD1A and monitor MCRIP1 expression. Decide whether this perturbation leads to a significant alteration in MCRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SETD1A and monitor MCRIP1 expression. Decide whether this perturbation leads to a significant alteration in MCRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 86400,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of PLXNA3 is measured. Does this perturbation cause a significant change in PLXNA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of PLXNA3 is measured. Does this perturbation cause a significant change in PLXNA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 43831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PKM and examine the expression of SP140. Does perturbing PKM lead to a significant change in SP140 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PKM and examine the expression of SP140. Does perturbing PKM lead to a significant change in SP140 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 83172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCDC115 is perturbed and CACNA2D1 expression is quantified. Does this perturbation result in a significant change in CACNA2D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCDC115 is perturbed and CACNA2D1 expression is quantified. Does this perturbation result in a significant change in CACNA2D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 86360,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR61 is perturbed and the expression of SLC25A23 is measured. Does this perturbation cause a significant change in SLC25A23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR61 is perturbed and the expression of SLC25A23 is measured. Does this perturbation cause a significant change in SLC25A23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MCL1 is perturbed and AC093323.1 expression is quantified. Does this perturbation result in a significant change in AC093323.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MCL1 is perturbed and AC093323.1 expression is quantified. Does this perturbation result in a significant change in AC093323.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 18319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AP2M1 is perturbed and PPARD expression is measured. Determine whether PPARD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AP2M1 is perturbed and PPARD expression is measured. Determine whether PPARD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 36859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TKT is perturbed and ECM1 expression is measured. Determine whether ECM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TKT is perturbed and ECM1 expression is measured. Determine whether ECM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 32904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCKAP1 and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCKAP1 and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3180,"You are an expert in single-cell biology and functional genomics. In K562 cells, H3F3A is perturbed and the expression of NDUFA12 is measured. Does this perturbation cause a significant change in NDUFA12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, H3F3A is perturbed and the expression of NDUFA12 is measured. Does this perturbation cause a significant change in NDUFA12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 35337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C1orf109, does the expression profile of ZCCHC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C1orf109, does the expression profile of ZCCHC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 48215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNHIT3 is associated with a significant change in TRPT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNHIT3 is associated with a significant change in TRPT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 92880,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS8 is perturbed and the expression of AC100810.1 is measured. Does this perturbation cause a significant change in AC100810.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS8 is perturbed and the expression of AC100810.1 is measured. Does this perturbation cause a significant change in AC100810.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 57445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SUDS3 is associated with a significant change in DLEU2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SUDS3 is associated with a significant change in DLEU2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 16538,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23B and monitor FAP expression. Decide whether this perturbation leads to a significant alteration in FAP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23B and monitor FAP expression. Decide whether this perturbation leads to a significant alteration in FAP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 9225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCP110 is associated with a significant change in SELENOM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCP110 is associated with a significant change in SELENOM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 39809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL28 is perturbed and DNAJC4 expression is measured. Determine whether DNAJC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL28 is perturbed and DNAJC4 expression is measured. Determine whether DNAJC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 55598,"You are a functional genomics specialist. In K562 cells, we perturb LAMB1 and monitor IFRD1 expression. Decide whether this perturbation leads to a significant alteration in IFRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LAMB1 and monitor IFRD1 expression. Decide whether this perturbation leads to a significant alteration in IFRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 23477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS23, does the expression profile of CPOX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS23, does the expression profile of CPOX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 98367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOSC3, does the expression profile of RNF25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOSC3, does the expression profile of RNF25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 120574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNTB2 and then measure expression of DSTYK. Does this perturbation cause a significant change in DSTYK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNTB2 and then measure expression of DSTYK. Does this perturbation cause a significant change in DSTYK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 86658,"You are a functional genomics specialist. In K562 cells, we perturb CDC42 and monitor SREK1IP1 expression. Decide whether this perturbation leads to a significant alteration in SREK1IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDC42 and monitor SREK1IP1 expression. Decide whether this perturbation leads to a significant alteration in SREK1IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 62309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POGZ is perturbed and NHLRC3 expression is measured. Determine whether NHLRC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POGZ is perturbed and NHLRC3 expression is measured. Determine whether NHLRC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 106602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PGAM1 is perturbed and ENTPD6 expression is quantified. Does this perturbation result in a significant change in ENTPD6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PGAM1 is perturbed and ENTPD6 expression is quantified. Does this perturbation result in a significant change in ENTPD6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 99705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUBP1 is associated with a significant change in BBS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUBP1 is associated with a significant change in BBS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 42235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLPB is associated with a significant change in RAB30-DT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLPB is associated with a significant change in RAB30-DT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 103098,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 48647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PXN, does the expression profile of SUGCT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PXN, does the expression profile of SUGCT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 36454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA3 and then measure expression of ICE2. Does this perturbation cause a significant change in ICE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA3 and then measure expression of ICE2. Does this perturbation cause a significant change in ICE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 79561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP43 and examine the expression of BDNF. Does perturbing NUP43 lead to a significant change in BDNF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP43 and examine the expression of BDNF. Does perturbing NUP43 lead to a significant change in BDNF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 109017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of RHOQ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of RHOQ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 78542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TOPBP1 is perturbed and SYF2 expression is quantified. Does this perturbation result in a significant change in SYF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TOPBP1 is perturbed and SYF2 expression is quantified. Does this perturbation result in a significant change in SYF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 86935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GGPS1 is associated with a significant change in GATAD2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GGPS1 is associated with a significant change in GATAD2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 27047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of THAP11, does the expression profile of UBXN8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of THAP11, does the expression profile of UBXN8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 41993,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC5 is perturbed and WARS expression is observed. Does this perturbation lead to a significant difference in WARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC5 is perturbed and WARS expression is observed. Does this perturbation lead to a significant difference in WARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 110075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUD13 is associated with a significant change in DUSP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUD13 is associated with a significant change in DUSP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 28136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PFDN1 is perturbed and the expression of ERLEC1 is measured. Determine whether ERLEC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PFDN1 is perturbed and the expression of ERLEC1 is measured. Determine whether ERLEC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 47962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METTL17 is perturbed and LINC02454 expression is quantified. Does this perturbation result in a significant change in LINC02454 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METTL17 is perturbed and LINC02454 expression is quantified. Does this perturbation result in a significant change in LINC02454 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 25949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL12 is perturbed and NSRP1 expression is measured. Determine whether NSRP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL12 is perturbed and NSRP1 expression is measured. Determine whether NSRP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 100115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMA16 is associated with a significant change in DNAAF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMA16 is associated with a significant change in DNAAF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 86450,"You are an expert in single-cell biology and functional genomics. In K562 cells, RANBP2 is perturbed and the expression of GGA1 is measured. Does this perturbation cause a significant change in GGA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RANBP2 is perturbed and the expression of GGA1 is measured. Does this perturbation cause a significant change in GGA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 20730,"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of ATXN3 is measured. Does this perturbation cause a significant change in ATXN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of ATXN3 is measured. Does this perturbation cause a significant change in ATXN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 43,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS31 is perturbed and DNAJC19 expression is observed. Does this perturbation lead to a significant difference in DNAJC19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS31 is perturbed and DNAJC19 expression is observed. Does this perturbation lead to a significant difference in DNAJC19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 61272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD4 is perturbed and ANGPT1 expression is quantified. Does this perturbation result in a significant change in ANGPT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD4 is perturbed and ANGPT1 expression is quantified. Does this perturbation result in a significant change in ANGPT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 58369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARMC6 is perturbed and POMGNT1 expression is measured. Determine whether POMGNT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARMC6 is perturbed and POMGNT1 expression is measured. Determine whether POMGNT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 96651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DSN1 and examine the expression of EXOC1. Does perturbing DSN1 lead to a significant change in EXOC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DSN1 and examine the expression of EXOC1. Does perturbing DSN1 lead to a significant change in EXOC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 60119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SUPV3L1 is perturbed and MT-ND4L expression is measured. Determine whether MT-ND4L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SUPV3L1 is perturbed and MT-ND4L expression is measured. Determine whether MT-ND4L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 24039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2F1 is perturbed and VCPIP1 expression is measured. Determine whether VCPIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2F1 is perturbed and VCPIP1 expression is measured. Determine whether VCPIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 15218,"You are a functional genomics specialist. In K562 cells, we perturb COG3 and monitor PMEPA1 expression. Decide whether this perturbation leads to a significant alteration in PMEPA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COG3 and monitor PMEPA1 expression. Decide whether this perturbation leads to a significant alteration in PMEPA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 63942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PHB2 is perturbed and UNC93B1 expression is quantified. Does this perturbation result in a significant change in UNC93B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PHB2 is perturbed and UNC93B1 expression is quantified. Does this perturbation result in a significant change in UNC93B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 108742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MED6 is perturbed and DHRSX expression is quantified. Does this perturbation result in a significant change in DHRSX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MED6 is perturbed and DHRSX expression is quantified. Does this perturbation result in a significant change in DHRSX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 54121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRKCA and examine the expression of SLC30A7. Does perturbing PRKCA lead to a significant change in SLC30A7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRKCA and examine the expression of SLC30A7. Does perturbing PRKCA lead to a significant change in SLC30A7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 82113,You are an expert in regulatory genomics. Consider data from K562 cells in which SETD2 is perturbed and SERINC5 expression is observed. Does this perturbation lead to a significant difference in SERINC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SETD2 is perturbed and SERINC5 expression is observed. Does this perturbation lead to a significant difference in SERINC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 60515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPH is associated with a significant change in TRIM52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPH is associated with a significant change in TRIM52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 90425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIN is associated with a significant change in YIPF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIN is associated with a significant change in YIPF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 44850,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLU7 is perturbed and the expression of ARFIP2 is measured. Does this perturbation cause a significant change in ARFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLU7 is perturbed and the expression of ARFIP2 is measured. Does this perturbation cause a significant change in ARFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 40903,You are an expert in regulatory genomics. Consider data from K562 cells in which E2F6 is perturbed and PREB expression is observed. Does this perturbation lead to a significant difference in PREB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which E2F6 is perturbed and PREB expression is observed. Does this perturbation lead to a significant difference in PREB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 34707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOL8, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOL8, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 9546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MFAP1 is perturbed and the expression of SPATA7 is measured. Determine whether SPATA7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MFAP1 is perturbed and the expression of SPATA7 is measured. Determine whether SPATA7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 106515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED7 is associated with a significant change in ATP6V1D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED7 is associated with a significant change in ATP6V1D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 68743,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF4A3 is perturbed and EMC2 expression is observed. Does this perturbation lead to a significant difference in EMC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF4A3 is perturbed and EMC2 expression is observed. Does this perturbation lead to a significant difference in EMC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 52655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAXX is associated with a significant change in CRIM1-DT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAXX is associated with a significant change in CRIM1-DT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 45527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRPF18, does the expression profile of BRAP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRPF18, does the expression profile of BRAP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 9838,"You are a functional genomics specialist. In K562 cells, we perturb NUDCD3 and monitor MPDZ expression. Decide whether this perturbation leads to a significant alteration in MPDZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NUDCD3 and monitor MPDZ expression. Decide whether this perturbation leads to a significant alteration in MPDZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 103651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP205 and examine the expression of ROGDI. Does perturbing NUP205 lead to a significant change in ROGDI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP205 and examine the expression of ROGDI. Does perturbing NUP205 lead to a significant change in ROGDI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCAF6 is associated with a significant change in COA7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCAF6 is associated with a significant change in COA7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 122230,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC37 is perturbed and the expression of GLUD1 is measured. Does this perturbation cause a significant change in GLUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC37 is perturbed and the expression of GLUD1 is measured. Does this perturbation cause a significant change in GLUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 48168,"You are a functional genomics specialist. In K562 cells, we perturb SNAPC4 and monitor G0S2 expression. Decide whether this perturbation leads to a significant alteration in G0S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SNAPC4 and monitor G0S2 expression. Decide whether this perturbation leads to a significant alteration in G0S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 116003,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SYNE1 expression is observed. Does this perturbation lead to a significant difference in SYNE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SYNE1 expression is observed. Does this perturbation lead to a significant difference in SYNE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 87016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS51 is perturbed and the expression of SELENOM is measured. Determine whether SELENOM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS51 is perturbed and the expression of SELENOM is measured. Determine whether SELENOM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 90466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIN is perturbed and the expression of PI4K2A is measured. Determine whether PI4K2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIN is perturbed and the expression of PI4K2A is measured. Determine whether PI4K2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 108601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF407 and examine the expression of HAUS2. Does perturbing ZNF407 lead to a significant change in HAUS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF407 and examine the expression of HAUS2. Does perturbing ZNF407 lead to a significant change in HAUS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 18938,"You are a functional genomics specialist. In K562 cells, we perturb CLCC1 and monitor HPS3 expression. Decide whether this perturbation leads to a significant alteration in HPS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CLCC1 and monitor HPS3 expression. Decide whether this perturbation leads to a significant alteration in HPS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 16369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM10 is perturbed and BDH2 expression is measured. Determine whether BDH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM10 is perturbed and BDH2 expression is measured. Determine whether BDH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 58285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2H3 is associated with a significant change in MPV17 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2H3 is associated with a significant change in MPV17 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 123462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLMN is perturbed and AAR2 expression is quantified. Does this perturbation result in a significant change in AAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLMN is perturbed and AAR2 expression is quantified. Does this perturbation result in a significant change in AAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 32395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZFC3H1 is associated with a significant change in GPALPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZFC3H1 is associated with a significant change in GPALPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 18071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KEAP1 and examine the expression of MRNIP. Does perturbing KEAP1 lead to a significant change in MRNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KEAP1 and examine the expression of MRNIP. Does perturbing KEAP1 lead to a significant change in MRNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 27444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to THOC7 and then measure expression of DDX27. Does this perturbation cause a significant change in DDX27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to THOC7 and then measure expression of DDX27. Does this perturbation cause a significant change in DDX27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 94843,You are an expert in regulatory genomics. Consider data from K562 cells in which UMPS is perturbed and SEC23B expression is observed. Does this perturbation lead to a significant difference in SEC23B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UMPS is perturbed and SEC23B expression is observed. Does this perturbation lead to a significant difference in SEC23B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 86870,"You are an expert in single-cell biology and functional genomics. In K562 cells, LARS is perturbed and the expression of RB1CC1 is measured. Does this perturbation cause a significant change in RB1CC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LARS is perturbed and the expression of RB1CC1 is measured. Does this perturbation cause a significant change in RB1CC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 51975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRIP1 is associated with a significant change in RHOA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRIP1 is associated with a significant change in RHOA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 14566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of MKNK1 is measured. Determine whether MKNK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of MKNK1 is measured. Determine whether MKNK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 54490,"You are an expert in single-cell biology and functional genomics. In K562 cells, GAPDH is perturbed and the expression of DDX27 is measured. Does this perturbation cause a significant change in DDX27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GAPDH is perturbed and the expression of DDX27 is measured. Does this perturbation cause a significant change in DDX27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 94994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of F8A1. Does this perturbation cause a significant change in F8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of F8A1. Does this perturbation cause a significant change in F8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 74219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AKIRIN2 is perturbed and RRAS expression is measured. Determine whether RRAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AKIRIN2 is perturbed and RRAS expression is measured. Determine whether RRAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 64011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD14 and examine the expression of SETD5. Does perturbing PSMD14 lead to a significant change in SETD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD14 and examine the expression of SETD5. Does perturbing PSMD14 lead to a significant change in SETD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 33190,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAD2L1 is perturbed and the expression of GBP1 is measured. Does this perturbation cause a significant change in GBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAD2L1 is perturbed and the expression of GBP1 is measured. Does this perturbation cause a significant change in GBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 30413,You are an expert in regulatory genomics. Consider data from K562 cells in which KRT10 is perturbed and NARS2 expression is observed. Does this perturbation lead to a significant difference in NARS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KRT10 is perturbed and NARS2 expression is observed. Does this perturbation lead to a significant difference in NARS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 121540,"You are an expert in single-cell biology and functional genomics. In K562 cells, FIP1L1 is perturbed and the expression of MRPL33 is measured. Does this perturbation cause a significant change in MRPL33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FIP1L1 is perturbed and the expression of MRPL33 is measured. Does this perturbation cause a significant change in MRPL33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 11942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPS is perturbed and PSMD10 expression is quantified. Does this perturbation result in a significant change in PSMD10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPS is perturbed and PSMD10 expression is quantified. Does this perturbation result in a significant change in PSMD10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 31706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR33 is perturbed and the expression of TP53TG1 is measured. Determine whether TP53TG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR33 is perturbed and the expression of TP53TG1 is measured. Determine whether TP53TG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 111121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FNTA and examine the expression of POLD4. Does perturbing FNTA lead to a significant change in POLD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FNTA and examine the expression of POLD4. Does perturbing FNTA lead to a significant change in POLD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 50933,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and MOB2 expression is observed. Does this perturbation lead to a significant difference in MOB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and MOB2 expression is observed. Does this perturbation lead to a significant difference in MOB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 21575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET1 is associated with a significant change in ADAMTS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET1 is associated with a significant change in ADAMTS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 90784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBX1 and then measure expression of ZBTB44. Does this perturbation cause a significant change in ZBTB44 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBX1 and then measure expression of ZBTB44. Does this perturbation cause a significant change in ZBTB44 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 121056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BANP is perturbed and the expression of CNN3 is measured. Determine whether CNN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BANP is perturbed and the expression of CNN3 is measured. Determine whether CNN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 97385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of THRAP3 is associated with a significant change in MYEF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of THRAP3 is associated with a significant change in MYEF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 8741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS11 and examine the expression of CENPA. Does perturbing MRPS11 lead to a significant change in CENPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS11 and examine the expression of CENPA. Does perturbing MRPS11 lead to a significant change in CENPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 39830,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL28 is perturbed and the expression of TVP23B is measured. Does this perturbation cause a significant change in TVP23B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL28 is perturbed and the expression of TVP23B is measured. Does this perturbation cause a significant change in TVP23B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 34025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TEFM is associated with a significant change in MAGI2-AS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TEFM is associated with a significant change in MAGI2-AS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 108446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL27A is perturbed and the expression of TOMM7 is measured. Determine whether TOMM7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL27A is perturbed and the expression of TOMM7 is measured. Determine whether TOMM7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 69397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PEX19, does the expression profile of SRA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PEX19, does the expression profile of SRA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 96304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSBP and then measure expression of ITGAV. Does this perturbation cause a significant change in ITGAV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSBP and then measure expression of ITGAV. Does this perturbation cause a significant change in ITGAV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 95549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBLL1 is perturbed and FAM155A expression is measured. Determine whether FAM155A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBLL1 is perturbed and FAM155A expression is measured. Determine whether FAM155A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 105209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1F is perturbed and PFKFB4 expression is measured. Determine whether PFKFB4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1F is perturbed and PFKFB4 expression is measured. Determine whether PFKFB4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 121316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of DEF8 is measured. Determine whether DEF8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of DEF8 is measured. Determine whether DEF8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 100292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PET117 is perturbed and ZFHX4 expression is quantified. Does this perturbation result in a significant change in ZFHX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PET117 is perturbed and ZFHX4 expression is quantified. Does this perturbation result in a significant change in ZFHX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 82593,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS7 is perturbed and AKT2 expression is observed. Does this perturbation lead to a significant difference in AKT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS7 is perturbed and AKT2 expression is observed. Does this perturbation lead to a significant difference in AKT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 117806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP62 is perturbed and the expression of AC005670.3 is measured. Determine whether AC005670.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP62 is perturbed and the expression of AC005670.3 is measured. Determine whether AC005670.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 113949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KATNB1 is perturbed and PLAT expression is measured. Determine whether PLAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KATNB1 is perturbed and PLAT expression is measured. Determine whether PLAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 9191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UNC45A and examine the expression of CASP2. Does perturbing UNC45A lead to a significant change in CASP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UNC45A and examine the expression of CASP2. Does perturbing UNC45A lead to a significant change in CASP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 116235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD39 is associated with a significant change in ZNF576 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD39 is associated with a significant change in ZNF576 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 90952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HMGCR is perturbed and YME1L1 expression is quantified. Does this perturbation result in a significant change in YME1L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HMGCR is perturbed and YME1L1 expression is quantified. Does this perturbation result in a significant change in YME1L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 119665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF5 is associated with a significant change in TARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF5 is associated with a significant change in TARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 80713,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL13 is perturbed and ENTPD7 expression is observed. Does this perturbation lead to a significant difference in ENTPD7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL13 is perturbed and ENTPD7 expression is observed. Does this perturbation lead to a significant difference in ENTPD7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 88339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BMS1 is perturbed and PON2 expression is measured. Determine whether PON2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BMS1 is perturbed and PON2 expression is measured. Determine whether PON2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 72833,You are an expert in regulatory genomics. Consider data from K562 cells in which ILF3 is perturbed and TUSC2 expression is observed. Does this perturbation lead to a significant difference in TUSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ILF3 is perturbed and TUSC2 expression is observed. Does this perturbation lead to a significant difference in TUSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 99049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PHF5A is perturbed and CCDC50 expression is measured. Determine whether CCDC50 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PHF5A is perturbed and CCDC50 expression is measured. Determine whether CCDC50 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 109463,You are an expert in regulatory genomics. Consider data from K562 cells in which ERH is perturbed and SUN1 expression is observed. Does this perturbation lead to a significant difference in SUN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ERH is perturbed and SUN1 expression is observed. Does this perturbation lead to a significant difference in SUN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 78717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD6, does the expression profile of BRD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD6, does the expression profile of BRD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 50212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNOT1 is perturbed and RSPH3 expression is quantified. Does this perturbation result in a significant change in RSPH3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNOT1 is perturbed and RSPH3 expression is quantified. Does this perturbation result in a significant change in RSPH3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 27762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QRSL1 is perturbed and AGO3 expression is quantified. Does this perturbation result in a significant change in AGO3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QRSL1 is perturbed and AGO3 expression is quantified. Does this perturbation result in a significant change in AGO3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 713,You are an expert in regulatory genomics. Consider data from K562 cells in which HAUS3 is perturbed and AGBL5 expression is observed. Does this perturbation lead to a significant difference in AGBL5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HAUS3 is perturbed and AGBL5 expression is observed. Does this perturbation lead to a significant difference in AGBL5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 23146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SHC1 is perturbed and the expression of MAP4K5 is measured. Determine whether MAP4K5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SHC1 is perturbed and the expression of MAP4K5 is measured. Determine whether MAP4K5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 19198,"You are a functional genomics specialist. In K562 cells, we perturb UPF2 and monitor TENT2 expression. Decide whether this perturbation leads to a significant alteration in TENT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UPF2 and monitor TENT2 expression. Decide whether this perturbation leads to a significant alteration in TENT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 90579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCBP2 is perturbed and WDR37 expression is measured. Determine whether WDR37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCBP2 is perturbed and WDR37 expression is measured. Determine whether WDR37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM242 is associated with a significant change in CAMK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM242 is associated with a significant change in CAMK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 66266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SKA1 is perturbed and the expression of IFNAR2 is measured. Determine whether IFNAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SKA1 is perturbed and the expression of IFNAR2 is measured. Determine whether IFNAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 112555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C7orf50 is associated with a significant change in H2AFY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C7orf50 is associated with a significant change in H2AFY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 118964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM8 and then measure expression of IMMT. Does this perturbation cause a significant change in IMMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM8 and then measure expression of IMMT. Does this perturbation cause a significant change in IMMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 100108,"You are a functional genomics specialist. In K562 cells, we perturb TMA16 and monitor BHMT2 expression. Decide whether this perturbation leads to a significant alteration in BHMT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMA16 and monitor BHMT2 expression. Decide whether this perturbation leads to a significant alteration in BHMT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 78701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZCCHC9 and examine the expression of TRIM25. Does perturbing ZCCHC9 lead to a significant change in TRIM25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZCCHC9 and examine the expression of TRIM25. Does perturbing ZCCHC9 lead to a significant change in TRIM25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 113623,You are an expert in regulatory genomics. Consider data from K562 cells in which SUGT1 is perturbed and ZYG11B expression is observed. Does this perturbation lead to a significant difference in ZYG11B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SUGT1 is perturbed and ZYG11B expression is observed. Does this perturbation lead to a significant difference in ZYG11B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 99615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPRC1 is associated with a significant change in PFDN6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPRC1 is associated with a significant change in PFDN6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 15539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PAF1 is perturbed and ENC1 expression is measured. Determine whether ENC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PAF1 is perturbed and ENC1 expression is measured. Determine whether ENC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 95901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAX and examine the expression of NDST2. Does perturbing MAX lead to a significant change in NDST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAX and examine the expression of NDST2. Does perturbing MAX lead to a significant change in NDST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCAF6 is perturbed and RPL10A expression is quantified. Does this perturbation result in a significant change in RPL10A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCAF6 is perturbed and RPL10A expression is quantified. Does this perturbation result in a significant change in RPL10A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 8003,You are an expert in regulatory genomics. Consider data from K562 cells in which HMGA1 is perturbed and WDR6 expression is observed. Does this perturbation lead to a significant difference in WDR6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HMGA1 is perturbed and WDR6 expression is observed. Does this perturbation lead to a significant difference in WDR6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 51037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3A, does the expression profile of SNHG32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3A, does the expression profile of SNHG32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 102433,You are an expert in regulatory genomics. Consider data from K562 cells in which DROSHA is perturbed and MIRLET7BHG expression is observed. Does this perturbation lead to a significant difference in MIRLET7BHG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DROSHA is perturbed and MIRLET7BHG expression is observed. Does this perturbation lead to a significant difference in MIRLET7BHG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 21684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PHF10 and then measure expression of LHFPL2. Does this perturbation cause a significant change in LHFPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PHF10 and then measure expression of LHFPL2. Does this perturbation cause a significant change in LHFPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 73343,You are an expert in regulatory genomics. Consider data from K562 cells in which POP5 is perturbed and LINC02742 expression is observed. Does this perturbation lead to a significant difference in LINC02742 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which POP5 is perturbed and LINC02742 expression is observed. Does this perturbation lead to a significant difference in LINC02742 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 11256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELOB is perturbed and the expression of WASHC3 is measured. Determine whether WASHC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELOB is perturbed and the expression of WASHC3 is measured. Determine whether WASHC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 78875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPC is associated with a significant change in MRPS33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPC is associated with a significant change in MRPS33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 54718,"You are a functional genomics specialist. In K562 cells, we perturb DPH6 and monitor ZNF217 expression. Decide whether this perturbation leads to a significant alteration in ZNF217 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DPH6 and monitor ZNF217 expression. Decide whether this perturbation leads to a significant alteration in ZNF217 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 94536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UQCRH is perturbed and the expression of RPL39L is measured. Determine whether RPL39L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UQCRH is perturbed and the expression of RPL39L is measured. Determine whether RPL39L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 74035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBBP5 is associated with a significant change in POLL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBBP5 is associated with a significant change in POLL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRC1, does the expression profile of RFX7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRC1, does the expression profile of RFX7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 71340,"You are an expert in single-cell biology and functional genomics. In K562 cells, PAK1IP1 is perturbed and the expression of DUSP3 is measured. Does this perturbation cause a significant change in DUSP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PAK1IP1 is perturbed and the expression of DUSP3 is measured. Does this perturbation cause a significant change in DUSP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 40237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MSRB1, does the expression profile of TMED5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MSRB1, does the expression profile of TMED5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 103067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDK12, does the expression profile of GID4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDK12, does the expression profile of GID4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 87428,"You are a functional genomics specialist. In K562 cells, we perturb RPL10A and monitor GET3 expression. Decide whether this perturbation leads to a significant alteration in GET3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RPL10A and monitor GET3 expression. Decide whether this perturbation leads to a significant alteration in GET3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 29145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJA3 is associated with a significant change in EPAS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJA3 is associated with a significant change in EPAS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRC1 and then measure expression of RFX7. Does this perturbation cause a significant change in RFX7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRC1 and then measure expression of RFX7. Does this perturbation cause a significant change in RFX7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 63452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS2 is perturbed and RBM22 expression is quantified. Does this perturbation result in a significant change in RBM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS2 is perturbed and RBM22 expression is quantified. Does this perturbation result in a significant change in RBM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 80154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS2 and then measure expression of THAP6. Does this perturbation cause a significant change in THAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS2 and then measure expression of THAP6. Does this perturbation cause a significant change in THAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 41757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WTAP, does the expression profile of TRIM8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WTAP, does the expression profile of TRIM8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 73438,"You are a functional genomics specialist. In K562 cells, we perturb CAP1 and monitor ZNF787 expression. Decide whether this perturbation leads to a significant alteration in ZNF787 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CAP1 and monitor ZNF787 expression. Decide whether this perturbation leads to a significant alteration in ZNF787 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 16935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2I is associated with a significant change in ANKS6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2I is associated with a significant change in ANKS6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, N6AMT1 is perturbed and CEP57L1 expression is quantified. Does this perturbation result in a significant change in CEP57L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, N6AMT1 is perturbed and CEP57L1 expression is quantified. Does this perturbation result in a significant change in CEP57L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 51797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALDOA, does the expression profile of ORC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALDOA, does the expression profile of ORC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 119983,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC1 is perturbed and CCNK expression is observed. Does this perturbation lead to a significant difference in CCNK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC1 is perturbed and CCNK expression is observed. Does this perturbation lead to a significant difference in CCNK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 10509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHPS is perturbed and NTAN1 expression is measured. Determine whether NTAN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHPS is perturbed and NTAN1 expression is measured. Determine whether NTAN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 44365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YPEL5 is associated with a significant change in FAM13A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YPEL5 is associated with a significant change in FAM13A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 30378,"You are a functional genomics specialist. In K562 cells, we perturb KRT10 and monitor SLC25A13 expression. Decide whether this perturbation leads to a significant alteration in SLC25A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KRT10 and monitor SLC25A13 expression. Decide whether this perturbation leads to a significant alteration in SLC25A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 96593,You are an expert in regulatory genomics. Consider data from K562 cells in which WDHD1 is perturbed and DAB2 expression is observed. Does this perturbation lead to a significant difference in DAB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which WDHD1 is perturbed and DAB2 expression is observed. Does this perturbation lead to a significant difference in DAB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 81167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDPK1, does the expression profile of NDUFB8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDPK1, does the expression profile of NDUFB8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 82313,You are an expert in regulatory genomics. Consider data from K562 cells in which TUBA1B is perturbed and SLC44A2 expression is observed. Does this perturbation lead to a significant difference in SLC44A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TUBA1B is perturbed and SLC44A2 expression is observed. Does this perturbation lead to a significant difference in SLC44A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 22562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3H4 is perturbed and LAMTOR5 expression is quantified. Does this perturbation result in a significant change in LAMTOR5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3H4 is perturbed and LAMTOR5 expression is quantified. Does this perturbation result in a significant change in LAMTOR5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 51812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBMX2 is perturbed and METTL16 expression is quantified. Does this perturbation result in a significant change in METTL16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBMX2 is perturbed and METTL16 expression is quantified. Does this perturbation result in a significant change in METTL16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 37260,"You are an expert in single-cell biology and functional genomics. In K562 cells, PARN is perturbed and the expression of SULF1 is measured. Does this perturbation cause a significant change in SULF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PARN is perturbed and the expression of SULF1 is measured. Does this perturbation cause a significant change in SULF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFS5 is perturbed and ARL6IP6 expression is quantified. Does this perturbation result in a significant change in ARL6IP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFS5 is perturbed and ARL6IP6 expression is quantified. Does this perturbation result in a significant change in ARL6IP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 99820,"You are an expert in single-cell biology and functional genomics. In K562 cells, CD2BP2 is perturbed and the expression of SKIV2L is measured. Does this perturbation cause a significant change in SKIV2L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CD2BP2 is perturbed and the expression of SKIV2L is measured. Does this perturbation cause a significant change in SKIV2L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 31985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC11 is associated with a significant change in ECHDC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC11 is associated with a significant change in ECHDC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 98446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PREB is perturbed and the expression of PLA2G4A is measured. Determine whether PLA2G4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PREB is perturbed and the expression of PLA2G4A is measured. Determine whether PLA2G4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 118724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AP2S1 and then measure expression of TOE1. Does this perturbation cause a significant change in TOE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AP2S1 and then measure expression of TOE1. Does this perturbation cause a significant change in TOE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 78583,You are an expert in regulatory genomics. Consider data from K562 cells in which TOPBP1 is perturbed and GSK3B expression is observed. Does this perturbation lead to a significant difference in GSK3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TOPBP1 is perturbed and GSK3B expression is observed. Does this perturbation lead to a significant difference in GSK3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 46636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELP6 is perturbed and the expression of DTD2 is measured. Determine whether DTD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELP6 is perturbed and the expression of DTD2 is measured. Determine whether DTD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 55523,You are an expert in regulatory genomics. Consider data from K562 cells in which GNL3 is perturbed and MLH3 expression is observed. Does this perturbation lead to a significant difference in MLH3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GNL3 is perturbed and MLH3 expression is observed. Does this perturbation lead to a significant difference in MLH3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 16797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNOT2, does the expression profile of MTCH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNOT2, does the expression profile of MTCH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 29214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP192 and then measure expression of INTS10. Does this perturbation cause a significant change in INTS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP192 and then measure expression of INTS10. Does this perturbation cause a significant change in INTS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 107370,"You are an expert in single-cell biology and functional genomics. In K562 cells, PWP1 is perturbed and the expression of PSEN2 is measured. Does this perturbation cause a significant change in PSEN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PWP1 is perturbed and the expression of PSEN2 is measured. Does this perturbation cause a significant change in PSEN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 95661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SMC6 and examine the expression of MRAS. Does perturbing SMC6 lead to a significant change in MRAS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SMC6 and examine the expression of MRAS. Does perturbing SMC6 lead to a significant change in MRAS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 51032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3A is perturbed and SNHG32 expression is quantified. Does this perturbation result in a significant change in SNHG32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3A is perturbed and SNHG32 expression is quantified. Does this perturbation result in a significant change in SNHG32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 110656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BYSL is perturbed and the expression of ZNHIT1 is measured. Determine whether ZNHIT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BYSL is perturbed and the expression of ZNHIT1 is measured. Determine whether ZNHIT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 30295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF6 is associated with a significant change in ZRANB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF6 is associated with a significant change in ZRANB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 79923,You are an expert in regulatory genomics. Consider data from K562 cells in which LAMTOR3 is perturbed and RRAGB expression is observed. Does this perturbation lead to a significant difference in RRAGB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LAMTOR3 is perturbed and RRAGB expression is observed. Does this perturbation lead to a significant difference in RRAGB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 86585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRIX1 is associated with a significant change in FAP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRIX1 is associated with a significant change in FAP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 79519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL55 is perturbed and MFN1 expression is measured. Determine whether MFN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL55 is perturbed and MFN1 expression is measured. Determine whether MFN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 23027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC84, does the expression profile of C2orf76 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC84, does the expression profile of C2orf76 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 33133,You are an expert in regulatory genomics. Consider data from K562 cells in which SYMPK is perturbed and IFT20 expression is observed. Does this perturbation lead to a significant difference in IFT20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SYMPK is perturbed and IFT20 expression is observed. Does this perturbation lead to a significant difference in IFT20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 67568,"You are a functional genomics specialist. In K562 cells, we perturb COG1 and monitor LBH expression. Decide whether this perturbation leads to a significant alteration in LBH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COG1 and monitor LBH expression. Decide whether this perturbation leads to a significant alteration in LBH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 107976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, METAP1 is perturbed and the expression of SGTB is measured. Determine whether SGTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, METAP1 is perturbed and the expression of SGTB is measured. Determine whether SGTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 69175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSAT1 is associated with a significant change in CHMP1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSAT1 is associated with a significant change in CHMP1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAP30BP is associated with a significant change in KCNK6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAP30BP is associated with a significant change in KCNK6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 37707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDK6, does the expression profile of RHBDD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDK6, does the expression profile of RHBDD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 114602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS7 is perturbed and RIOK3 expression is quantified. Does this perturbation result in a significant change in RIOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS7 is perturbed and RIOK3 expression is quantified. Does this perturbation result in a significant change in RIOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 9788,"You are a functional genomics specialist. In K562 cells, we perturb PRRC2A and monitor NFKBIL1 expression. Decide whether this perturbation leads to a significant alteration in NFKBIL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PRRC2A and monitor NFKBIL1 expression. Decide whether this perturbation leads to a significant alteration in NFKBIL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 49032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PI4KA is perturbed and TPRA1 expression is quantified. Does this perturbation result in a significant change in TPRA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PI4KA is perturbed and TPRA1 expression is quantified. Does this perturbation result in a significant change in TPRA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 89843,You are an expert in regulatory genomics. Consider data from K562 cells in which TUBGCP3 is perturbed and SETDB1 expression is observed. Does this perturbation lead to a significant difference in SETDB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TUBGCP3 is perturbed and SETDB1 expression is observed. Does this perturbation lead to a significant difference in SETDB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 94984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of C5orf46. Does this perturbation cause a significant change in C5orf46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of C5orf46. Does this perturbation cause a significant change in C5orf46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 95204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOMM22 and then measure expression of GNS. Does this perturbation cause a significant change in GNS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOMM22 and then measure expression of GNS. Does this perturbation cause a significant change in GNS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 120174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP10 and then measure expression of COPZ2. Does this perturbation cause a significant change in COPZ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP10 and then measure expression of COPZ2. Does this perturbation cause a significant change in COPZ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 10232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HECTD1 is perturbed and FNIP2 expression is quantified. Does this perturbation result in a significant change in FNIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HECTD1 is perturbed and FNIP2 expression is quantified. Does this perturbation result in a significant change in FNIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 74249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AKIRIN2 is perturbed and TTN-AS1 expression is measured. Determine whether TTN-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AKIRIN2 is perturbed and TTN-AS1 expression is measured. Determine whether TTN-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 16184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC3 and then measure expression of GPATCH2L. Does this perturbation cause a significant change in GPATCH2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC3 and then measure expression of GPATCH2L. Does this perturbation cause a significant change in GPATCH2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 115709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC8 is perturbed and PYCR1 expression is measured. Determine whether PYCR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC8 is perturbed and PYCR1 expression is measured. Determine whether PYCR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 123601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of PDLIM4. Does perturbing CCT5 lead to a significant change in PDLIM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of PDLIM4. Does perturbing CCT5 lead to a significant change in PDLIM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 53690,"You are an expert in single-cell biology and functional genomics. In K562 cells, RSL24D1 is perturbed and the expression of PAPPA is measured. Does this perturbation cause a significant change in PAPPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RSL24D1 is perturbed and the expression of PAPPA is measured. Does this perturbation cause a significant change in PAPPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 97476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NF1 is perturbed and the expression of LRP12 is measured. Determine whether LRP12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NF1 is perturbed and the expression of LRP12 is measured. Determine whether LRP12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 9654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V1G1 and then measure expression of PCNX1. Does this perturbation cause a significant change in PCNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V1G1 and then measure expression of PCNX1. Does this perturbation cause a significant change in PCNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 74051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBBP5 and examine the expression of GABARAPL2. Does perturbing RBBP5 lead to a significant change in GABARAPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBBP5 and examine the expression of GABARAPL2. Does perturbing RBBP5 lead to a significant change in GABARAPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 100672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and DNAJC3 expression is quantified. Does this perturbation result in a significant change in DNAJC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and DNAJC3 expression is quantified. Does this perturbation result in a significant change in DNAJC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 27662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS6 is perturbed and PLXNA1 expression is quantified. Does this perturbation result in a significant change in PLXNA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS6 is perturbed and PLXNA1 expression is quantified. Does this perturbation result in a significant change in PLXNA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 102526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOC5 is perturbed and the expression of PPP4R3B is measured. Determine whether PPP4R3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOC5 is perturbed and the expression of PPP4R3B is measured. Determine whether PPP4R3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 104955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR3D is associated with a significant change in BTBD10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR3D is associated with a significant change in BTBD10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 61935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAB4B is associated with a significant change in RAB11FIP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAB4B is associated with a significant change in RAB11FIP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 68533,You are an expert in regulatory genomics. Consider data from K562 cells in which RBM42 is perturbed and DPP7 expression is observed. Does this perturbation lead to a significant difference in DPP7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RBM42 is perturbed and DPP7 expression is observed. Does this perturbation lead to a significant difference in DPP7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 93216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LSM7 is perturbed and the expression of DDX27 is measured. Determine whether DDX27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LSM7 is perturbed and the expression of DDX27 is measured. Determine whether DDX27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 60144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPV3L1 and then measure expression of NFKBIB. Does this perturbation cause a significant change in NFKBIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPV3L1 and then measure expression of NFKBIB. Does this perturbation cause a significant change in NFKBIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 67081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS22 and examine the expression of PFDN4. Does perturbing MRPS22 lead to a significant change in PFDN4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS22 and examine the expression of PFDN4. Does perturbing MRPS22 lead to a significant change in PFDN4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 120728,"You are a functional genomics specialist. In K562 cells, we perturb SLC35A4 and monitor VAMP5 expression. Decide whether this perturbation leads to a significant alteration in VAMP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC35A4 and monitor VAMP5 expression. Decide whether this perturbation leads to a significant alteration in VAMP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 91903,You are an expert in regulatory genomics. Consider data from K562 cells in which DHX37 is perturbed and SH3D21 expression is observed. Does this perturbation lead to a significant difference in SH3D21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DHX37 is perturbed and SH3D21 expression is observed. Does this perturbation lead to a significant difference in SH3D21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 24474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYF2 and then measure expression of APAF1. Does this perturbation cause a significant change in APAF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYF2 and then measure expression of APAF1. Does this perturbation cause a significant change in APAF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 57684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCNM1 and then measure expression of SECISBP2L. Does this perturbation cause a significant change in SECISBP2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCNM1 and then measure expression of SECISBP2L. Does this perturbation cause a significant change in SECISBP2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 29368,"You are a functional genomics specialist. In K562 cells, we perturb ANAPC4 and monitor HEXIM1 expression. Decide whether this perturbation leads to a significant alteration in HEXIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ANAPC4 and monitor HEXIM1 expression. Decide whether this perturbation leads to a significant alteration in HEXIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SART1 is perturbed and GTF2IRD1 expression is measured. Determine whether GTF2IRD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SART1 is perturbed and GTF2IRD1 expression is measured. Determine whether GTF2IRD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 31849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UQCRC1 is perturbed and AP002360.1 expression is measured. Determine whether AP002360.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UQCRC1 is perturbed and AP002360.1 expression is measured. Determine whether AP002360.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 87397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CWF19L2, does the expression profile of GABPB1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CWF19L2, does the expression profile of GABPB1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 110994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBCC and then measure expression of KLHDC2. Does this perturbation cause a significant change in KLHDC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBCC and then measure expression of KLHDC2. Does this perturbation cause a significant change in KLHDC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 10929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GART is perturbed and CAVIN1 expression is measured. Determine whether CAVIN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GART is perturbed and CAVIN1 expression is measured. Determine whether CAVIN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 78428,"You are a functional genomics specialist. In K562 cells, we perturb YARS and monitor PPP1R15A expression. Decide whether this perturbation leads to a significant alteration in PPP1R15A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb YARS and monitor PPP1R15A expression. Decide whether this perturbation leads to a significant alteration in PPP1R15A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MALSU1, does the expression profile of MT-ATP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MALSU1, does the expression profile of MT-ATP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 59787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LETM1, does the expression profile of NAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LETM1, does the expression profile of NAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 71861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRK1 and examine the expression of ZNF280D. Does perturbing BRK1 lead to a significant change in ZNF280D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRK1 and examine the expression of ZNF280D. Does perturbing BRK1 lead to a significant change in ZNF280D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 77179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LONP1 is perturbed and LARP6 expression is measured. Determine whether LARP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LONP1 is perturbed and LARP6 expression is measured. Determine whether LARP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 15023,You are an expert in regulatory genomics. Consider data from K562 cells in which PPP1R7 is perturbed and FBXW5 expression is observed. Does this perturbation lead to a significant difference in FBXW5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PPP1R7 is perturbed and FBXW5 expression is observed. Does this perturbation lead to a significant difference in FBXW5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 45437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBPL1, does the expression profile of CCDC174 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBPL1, does the expression profile of CCDC174 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 116063,You are an expert in regulatory genomics. Consider data from K562 cells in which FARS2 is perturbed and ITGA1 expression is observed. Does this perturbation lead to a significant difference in ITGA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FARS2 is perturbed and ITGA1 expression is observed. Does this perturbation lead to a significant difference in ITGA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 100964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RNF168 and then measure expression of MRPL55. Does this perturbation cause a significant change in MRPL55 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RNF168 and then measure expression of MRPL55. Does this perturbation cause a significant change in MRPL55 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 119039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SSRP1 is perturbed and CSNK2A2 expression is measured. Determine whether CSNK2A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SSRP1 is perturbed and CSNK2A2 expression is measured. Determine whether CSNK2A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 108285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHEK1 is associated with a significant change in PEX26 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHEK1 is associated with a significant change in PEX26 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 96281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC5 and examine the expression of OSER1. Does perturbing THOC5 lead to a significant change in OSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC5 and examine the expression of OSER1. Does perturbing THOC5 lead to a significant change in OSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 46982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAE1 is perturbed and WDR55 expression is quantified. Does this perturbation result in a significant change in WDR55 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAE1 is perturbed and WDR55 expression is quantified. Does this perturbation result in a significant change in WDR55 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 62533,You are an expert in regulatory genomics. Consider data from K562 cells in which DESI1 is perturbed and PI4K2A expression is observed. Does this perturbation lead to a significant difference in PI4K2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DESI1 is perturbed and PI4K2A expression is observed. Does this perturbation lead to a significant difference in PI4K2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 14195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARIH1 is associated with a significant change in GLTP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARIH1 is associated with a significant change in GLTP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 117398,"You are a functional genomics specialist. In K562 cells, we perturb GTF2E1 and monitor PHB expression. Decide whether this perturbation leads to a significant alteration in PHB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GTF2E1 and monitor PHB expression. Decide whether this perturbation leads to a significant alteration in PHB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 77944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMARCC1 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMARCC1 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 104757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFB10, does the expression profile of G6PD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFB10, does the expression profile of G6PD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 42193,You are an expert in regulatory genomics. Consider data from K562 cells in which TSG101 is perturbed and CNOT8 expression is observed. Does this perturbation lead to a significant difference in CNOT8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TSG101 is perturbed and CNOT8 expression is observed. Does this perturbation lead to a significant difference in CNOT8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 48840,"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM2 is perturbed and the expression of MOSPD2 is measured. Does this perturbation cause a significant change in MOSPD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM2 is perturbed and the expression of MOSPD2 is measured. Does this perturbation cause a significant change in MOSPD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 48961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZWINT and examine the expression of MRPS10. Does perturbing ZWINT lead to a significant change in MRPS10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZWINT and examine the expression of MRPS10. Does perturbing ZWINT lead to a significant change in MRPS10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 11545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLRX3 is associated with a significant change in MRPL49 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLRX3 is associated with a significant change in MRPL49 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 92935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNF31 is associated with a significant change in FGF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNF31 is associated with a significant change in FGF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1853,You are an expert in regulatory genomics. Consider data from K562 cells in which PSTK is perturbed and KDELR3 expression is observed. Does this perturbation lead to a significant difference in KDELR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSTK is perturbed and KDELR3 expression is observed. Does this perturbation lead to a significant difference in KDELR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 8441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IST1 and examine the expression of MARCH3. Does perturbing IST1 lead to a significant change in MARCH3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IST1 and examine the expression of MARCH3. Does perturbing IST1 lead to a significant change in MARCH3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 90717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHAF1B, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHAF1B, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 48037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18A, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18A, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 109667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM7, does the expression profile of ANKRD50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM7, does the expression profile of ANKRD50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 99792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CD2BP2 is perturbed and CDK7 expression is quantified. Does this perturbation result in a significant change in CDK7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CD2BP2 is perturbed and CDK7 expression is quantified. Does this perturbation result in a significant change in CDK7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 66852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL17 is perturbed and ITPR1 expression is quantified. Does this perturbation result in a significant change in ITPR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL17 is perturbed and ITPR1 expression is quantified. Does this perturbation result in a significant change in ITPR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 45791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNRNPR and examine the expression of EIF2S2. Does perturbing HNRNPR lead to a significant change in EIF2S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNRNPR and examine the expression of EIF2S2. Does perturbing HNRNPR lead to a significant change in EIF2S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 96314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSBP and then measure expression of UBE2E1. Does this perturbation cause a significant change in UBE2E1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSBP and then measure expression of UBE2E1. Does this perturbation cause a significant change in UBE2E1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 102493,You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC5 is perturbed and BAZ2B expression is observed. Does this perturbation lead to a significant difference in BAZ2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC5 is perturbed and BAZ2B expression is observed. Does this perturbation lead to a significant difference in BAZ2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 77532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMG7 is perturbed and USP25 expression is quantified. Does this perturbation result in a significant change in USP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMG7 is perturbed and USP25 expression is quantified. Does this perturbation result in a significant change in USP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 20309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCFD1 is perturbed and SEC31A expression is measured. Determine whether SEC31A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCFD1 is perturbed and SEC31A expression is measured. Determine whether SEC31A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 82105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SETD2 is associated with a significant change in INPP5F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SETD2 is associated with a significant change in INPP5F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 43361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOP2 and examine the expression of ETFRF1. Does perturbing NOP2 lead to a significant change in ETFRF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOP2 and examine the expression of ETFRF1. Does perturbing NOP2 lead to a significant change in ETFRF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 32889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POP7 is perturbed and XRCC4 expression is measured. Determine whether XRCC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POP7 is perturbed and XRCC4 expression is measured. Determine whether XRCC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 70149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, REXO2 is perturbed and TENT5A expression is measured. Determine whether TENT5A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, REXO2 is perturbed and TENT5A expression is measured. Determine whether TENT5A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 102278,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor CHD3 expression. Decide whether this perturbation leads to a significant alteration in CHD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor CHD3 expression. Decide whether this perturbation leads to a significant alteration in CHD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 32936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCKAP1 is perturbed and the expression of TLE1 is measured. Determine whether TLE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCKAP1 is perturbed and the expression of TLE1 is measured. Determine whether TLE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 28919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC7A5 is perturbed and SLC2A11 expression is measured. Determine whether SLC2A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC7A5 is perturbed and SLC2A11 expression is measured. Determine whether SLC2A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 39067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LAS1L, does the expression profile of LINC00662 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LAS1L, does the expression profile of LINC00662 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 122747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED27, does the expression profile of ARHGEF28 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED27, does the expression profile of ARHGEF28 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 41127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHODH, does the expression profile of GTF3C4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHODH, does the expression profile of GTF3C4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 33481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HMGCS1 and examine the expression of BMERB1. Does perturbing HMGCS1 lead to a significant change in BMERB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HMGCS1 and examine the expression of BMERB1. Does perturbing HMGCS1 lead to a significant change in BMERB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 86125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5ME is associated with a significant change in UQCC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5ME is associated with a significant change in UQCC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 25210,"You are an expert in single-cell biology and functional genomics. In K562 cells, RRP15 is perturbed and the expression of JPX is measured. Does this perturbation cause a significant change in JPX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RRP15 is perturbed and the expression of JPX is measured. Does this perturbation cause a significant change in JPX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 95950,"You are an expert in single-cell biology and functional genomics. In K562 cells, NAPA is perturbed and the expression of TPP1 is measured. Does this perturbation cause a significant change in TPP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NAPA is perturbed and the expression of TPP1 is measured. Does this perturbation cause a significant change in TPP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 32368,"You are a functional genomics specialist. In K562 cells, we perturb ZFC3H1 and monitor DANCR expression. Decide whether this perturbation leads to a significant alteration in DANCR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZFC3H1 and monitor DANCR expression. Decide whether this perturbation leads to a significant alteration in DANCR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 117508,"You are a functional genomics specialist. In K562 cells, we perturb NSL1 and monitor CCNG2 expression. Decide whether this perturbation leads to a significant alteration in CCNG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NSL1 and monitor CCNG2 expression. Decide whether this perturbation leads to a significant alteration in CCNG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 91549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL42 is perturbed and TK2 expression is measured. Determine whether TK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL42 is perturbed and TK2 expression is measured. Determine whether TK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 51302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRCC1 is perturbed and CEP89 expression is quantified. Does this perturbation result in a significant change in CEP89 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRCC1 is perturbed and CEP89 expression is quantified. Does this perturbation result in a significant change in CEP89 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 72414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX7B and then measure expression of TMEM8A. Does this perturbation cause a significant change in TMEM8A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX7B and then measure expression of TMEM8A. Does this perturbation cause a significant change in TMEM8A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 25398,"You are a functional genomics specialist. In K562 cells, we perturb SMC4 and monitor SPAG9 expression. Decide whether this perturbation leads to a significant alteration in SPAG9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SMC4 and monitor SPAG9 expression. Decide whether this perturbation leads to a significant alteration in SPAG9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYBBP1A and examine the expression of GRINA. Does perturbing MYBBP1A lead to a significant change in GRINA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYBBP1A and examine the expression of GRINA. Does perturbing MYBBP1A lead to a significant change in GRINA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 117451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF3C5 and examine the expression of RPS28. Does perturbing GTF3C5 lead to a significant change in RPS28 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF3C5 and examine the expression of RPS28. Does perturbing GTF3C5 lead to a significant change in RPS28 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 12670,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1D is perturbed and the expression of RAD1 is measured. Does this perturbation cause a significant change in RAD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1D is perturbed and the expression of RAD1 is measured. Does this perturbation cause a significant change in RAD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 38301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NFYC and examine the expression of ANGPT1. Does perturbing NFYC lead to a significant change in ANGPT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NFYC and examine the expression of ANGPT1. Does perturbing NFYC lead to a significant change in ANGPT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 40906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, E2F6 is perturbed and the expression of PREB is measured. Determine whether PREB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, E2F6 is perturbed and the expression of PREB is measured. Determine whether PREB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 83788,"You are a functional genomics specialist. In K562 cells, we perturb E4F1 and monitor ST7 expression. Decide whether this perturbation leads to a significant alteration in ST7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb E4F1 and monitor ST7 expression. Decide whether this perturbation leads to a significant alteration in ST7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 31835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UQCRC1 is associated with a significant change in RING1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UQCRC1 is associated with a significant change in RING1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 108075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INO80 is associated with a significant change in FECH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INO80 is associated with a significant change in FECH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 31881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H18 and examine the expression of MAP2K3. Does perturbing ZC3H18 lead to a significant change in MAP2K3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H18 and examine the expression of MAP2K3. Does perturbing ZC3H18 lead to a significant change in MAP2K3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 59747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX54, does the expression profile of RAB10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX54, does the expression profile of RAB10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 45179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB17 is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB17 is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 73543,You are an expert in regulatory genomics. Consider data from K562 cells in which WARS is perturbed and LINC02057 expression is observed. Does this perturbation lead to a significant difference in LINC02057 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which WARS is perturbed and LINC02057 expression is observed. Does this perturbation lead to a significant difference in LINC02057 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 97740,"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP14 is perturbed and the expression of CHPF is measured. Does this perturbation cause a significant change in CHPF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP14 is perturbed and the expression of CHPF is measured. Does this perturbation cause a significant change in CHPF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, METTL21A is perturbed and the expression of SGK3 is measured. Determine whether SGK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, METTL21A is perturbed and the expression of SGK3 is measured. Determine whether SGK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 53969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR8 is perturbed and RNMT expression is measured. Determine whether RNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR8 is perturbed and RNMT expression is measured. Determine whether RNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 95729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAMM41 is perturbed and MICU3 expression is measured. Determine whether MICU3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAMM41 is perturbed and MICU3 expression is measured. Determine whether MICU3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 108450,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL27A is perturbed and the expression of SNHG19 is measured. Does this perturbation cause a significant change in SNHG19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL27A is perturbed and the expression of SNHG19 is measured. Does this perturbation cause a significant change in SNHG19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 109456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ERH is perturbed and the expression of AC016831.1 is measured. Determine whether AC016831.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ERH is perturbed and the expression of AC016831.1 is measured. Determine whether AC016831.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 87113,You are an expert in regulatory genomics. Consider data from K562 cells in which PHF12 is perturbed and ZNF622 expression is observed. Does this perturbation lead to a significant difference in ZNF622 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PHF12 is perturbed and ZNF622 expression is observed. Does this perturbation lead to a significant difference in ZNF622 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 40998,"You are a functional genomics specialist. In K562 cells, we perturb SRRM2 and monitor DYNC2LI1 expression. Decide whether this perturbation leads to a significant alteration in DYNC2LI1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRRM2 and monitor DYNC2LI1 expression. Decide whether this perturbation leads to a significant alteration in DYNC2LI1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 118544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MCEE and then measure expression of ZDHHC17. Does this perturbation cause a significant change in ZDHHC17 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MCEE and then measure expression of ZDHHC17. Does this perturbation cause a significant change in ZDHHC17 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 119768,"You are a functional genomics specialist. In K562 cells, we perturb PSMB7 and monitor SLC66A1 expression. Decide whether this perturbation leads to a significant alteration in SLC66A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMB7 and monitor SLC66A1 expression. Decide whether this perturbation leads to a significant alteration in SLC66A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 64391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LARS2 and examine the expression of WDYHV1. Does perturbing LARS2 lead to a significant change in WDYHV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LARS2 and examine the expression of WDYHV1. Does perturbing LARS2 lead to a significant change in WDYHV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDC6 and examine the expression of TLCD3A. Does perturbing CDC6 lead to a significant change in TLCD3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDC6 and examine the expression of TLCD3A. Does perturbing CDC6 lead to a significant change in TLCD3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 66712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL13 is perturbed and SURF1 expression is quantified. Does this perturbation result in a significant change in SURF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL13 is perturbed and SURF1 expression is quantified. Does this perturbation result in a significant change in SURF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 72107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CENPA, does the expression profile of RAD50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CENPA, does the expression profile of RAD50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 12356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPLP0 is perturbed and the expression of NR3C1 is measured. Determine whether NR3C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPLP0 is perturbed and the expression of NR3C1 is measured. Determine whether NR3C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 57857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRRT, does the expression profile of DNASE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRRT, does the expression profile of DNASE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 53534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB1 and then measure expression of RSBN1L. Does this perturbation cause a significant change in RSBN1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB1 and then measure expression of RSBN1L. Does this perturbation cause a significant change in RSBN1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 69284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DYNLL2 and then measure expression of GPN2. Does this perturbation cause a significant change in GPN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DYNLL2 and then measure expression of GPN2. Does this perturbation cause a significant change in GPN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3160,"You are an expert in single-cell biology and functional genomics. In K562 cells, H3F3A is perturbed and the expression of CENPO is measured. Does this perturbation cause a significant change in CENPO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, H3F3A is perturbed and the expression of CENPO is measured. Does this perturbation cause a significant change in CENPO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 102441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DROSHA and examine the expression of RAB38. Does perturbing DROSHA lead to a significant change in RAB38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DROSHA and examine the expression of RAB38. Does perturbing DROSHA lead to a significant change in RAB38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 67852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IWS1 is perturbed and COPZ2 expression is quantified. Does this perturbation result in a significant change in COPZ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IWS1 is perturbed and COPZ2 expression is quantified. Does this perturbation result in a significant change in COPZ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 101721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP23 and examine the expression of CFAP36. Does perturbing UTP23 lead to a significant change in CFAP36 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP23 and examine the expression of CFAP36. Does perturbing UTP23 lead to a significant change in CFAP36 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 22535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3H4 is associated with a significant change in ZCCHC24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3H4 is associated with a significant change in ZCCHC24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 83836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYRM4 is perturbed and the expression of CYFIP2 is measured. Determine whether CYFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYRM4 is perturbed and the expression of CYFIP2 is measured. Determine whether CYFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 36747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ABHD11, does the expression profile of SUGCT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ABHD11, does the expression profile of SUGCT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 105258,"You are a functional genomics specialist. In K562 cells, we perturb CEP152 and monitor CPA4 expression. Decide whether this perturbation leads to a significant alteration in CPA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEP152 and monitor CPA4 expression. Decide whether this perturbation leads to a significant alteration in CPA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 59017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUBP2, does the expression profile of APP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUBP2, does the expression profile of APP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 50439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC3 is perturbed and RBP1 expression is measured. Determine whether RBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC3 is perturbed and RBP1 expression is measured. Determine whether RBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 81394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS7 and then measure expression of DCTN5. Does this perturbation cause a significant change in DCTN5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS7 and then measure expression of DCTN5. Does this perturbation cause a significant change in DCTN5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HEATR1, does the expression profile of IDS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HEATR1, does the expression profile of IDS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 44034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELP3 and then measure expression of SAT1. Does this perturbation cause a significant change in SAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELP3 and then measure expression of SAT1. Does this perturbation cause a significant change in SAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 17172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS17 is perturbed and MSH2 expression is quantified. Does this perturbation result in a significant change in MSH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS17 is perturbed and MSH2 expression is quantified. Does this perturbation result in a significant change in MSH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 45674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MPHOSPH6 and then measure expression of BCKDHB. Does this perturbation cause a significant change in BCKDHB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MPHOSPH6 and then measure expression of BCKDHB. Does this perturbation cause a significant change in BCKDHB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 10405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VPS41 is associated with a significant change in FAM155A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VPS41 is associated with a significant change in FAM155A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 29545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED19 is associated with a significant change in TRAPPC2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED19 is associated with a significant change in TRAPPC2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 20255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS8 is associated with a significant change in SELENOM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS8 is associated with a significant change in SELENOM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 20195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPA1 is associated with a significant change in GSDME expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPA1 is associated with a significant change in GSDME expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 34689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP10 is perturbed and NABP2 expression is measured. Determine whether NABP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP10 is perturbed and NABP2 expression is measured. Determine whether NABP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 102401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC6 and examine the expression of ATP6V0C. Does perturbing PSMC6 lead to a significant change in ATP6V0C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC6 and examine the expression of ATP6V0C. Does perturbing PSMC6 lead to a significant change in ATP6V0C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAMLG, does the expression profile of COX4I1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAMLG, does the expression profile of COX4I1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 121227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP54, does the expression profile of LEPROT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP54, does the expression profile of LEPROT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 86776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL36A is perturbed and the expression of VSIR is measured. Determine whether VSIR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL36A is perturbed and the expression of VSIR is measured. Determine whether VSIR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 20162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARPC4 is perturbed and RELCH expression is quantified. Does this perturbation result in a significant change in RELCH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARPC4 is perturbed and RELCH expression is quantified. Does this perturbation result in a significant change in RELCH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 15056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF11 is perturbed and the expression of SAT1 is measured. Determine whether SAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF11 is perturbed and the expression of SAT1 is measured. Determine whether SAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT112 and examine the expression of PDLIM7. Does perturbing TRMT112 lead to a significant change in PDLIM7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT112 and examine the expression of PDLIM7. Does perturbing TRMT112 lead to a significant change in PDLIM7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 62048,"You are a functional genomics specialist. In K562 cells, we perturb MEF2A and monitor CHPF2 expression. Decide whether this perturbation leads to a significant alteration in CHPF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MEF2A and monitor CHPF2 expression. Decide whether this perturbation leads to a significant alteration in CHPF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 320,"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD5 is perturbed and the expression of KDM4C is measured. Does this perturbation cause a significant change in KDM4C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD5 is perturbed and the expression of KDM4C is measured. Does this perturbation cause a significant change in KDM4C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 102141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HAUS1 and examine the expression of PGAP1. Does perturbing HAUS1 lead to a significant change in PGAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HAUS1 and examine the expression of PGAP1. Does perturbing HAUS1 lead to a significant change in PGAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 47603,You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC2 is perturbed and YBX1 expression is observed. Does this perturbation lead to a significant difference in YBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC2 is perturbed and YBX1 expression is observed. Does this perturbation lead to a significant difference in YBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 73235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PITRM1 is associated with a significant change in AASDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PITRM1 is associated with a significant change in AASDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 14794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC27 and then measure expression of LETMD1. Does this perturbation cause a significant change in LETMD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC27 and then measure expression of LETMD1. Does this perturbation cause a significant change in LETMD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 56414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC1 and then measure expression of CERT1. Does this perturbation cause a significant change in CERT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC1 and then measure expression of CERT1. Does this perturbation cause a significant change in CERT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 56386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELAC2 is perturbed and the expression of MORN4 is measured. Determine whether MORN4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELAC2 is perturbed and the expression of MORN4 is measured. Determine whether MORN4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 122204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IFITM2 and then measure expression of DYNC2LI1. Does this perturbation cause a significant change in DYNC2LI1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IFITM2 and then measure expression of DYNC2LI1. Does this perturbation cause a significant change in DYNC2LI1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2220,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFS5 is perturbed and the expression of FGFRL1 is measured. Does this perturbation cause a significant change in FGFRL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFS5 is perturbed and the expression of FGFRL1 is measured. Does this perturbation cause a significant change in FGFRL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 115177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF7, does the expression profile of MOK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF7, does the expression profile of MOK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 30142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNHIT2 is perturbed and LMBR1 expression is quantified. Does this perturbation result in a significant change in LMBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNHIT2 is perturbed and LMBR1 expression is quantified. Does this perturbation result in a significant change in LMBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 16947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL26, does the expression profile of CCNL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL26, does the expression profile of CCNL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 32434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of AGRN. Does this perturbation cause a significant change in AGRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of AGRN. Does this perturbation cause a significant change in AGRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 36712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL30 is perturbed and RBM45 expression is quantified. Does this perturbation result in a significant change in RBM45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL30 is perturbed and RBM45 expression is quantified. Does this perturbation result in a significant change in RBM45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 67779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VEZT is perturbed and UTP23 expression is measured. Determine whether UTP23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VEZT is perturbed and UTP23 expression is measured. Determine whether UTP23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 54580,"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR3H is perturbed and the expression of NREP is measured. Does this perturbation cause a significant change in NREP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR3H is perturbed and the expression of NREP is measured. Does this perturbation cause a significant change in NREP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 91672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHX16 is perturbed and NAT9 expression is quantified. Does this perturbation result in a significant change in NAT9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHX16 is perturbed and NAT9 expression is quantified. Does this perturbation result in a significant change in NAT9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 100002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOC1 is perturbed and QRSL1 expression is quantified. Does this perturbation result in a significant change in QRSL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOC1 is perturbed and QRSL1 expression is quantified. Does this perturbation result in a significant change in QRSL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 75094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CUL1 and then measure expression of BECN1. Does this perturbation cause a significant change in BECN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CUL1 and then measure expression of BECN1. Does this perturbation cause a significant change in BECN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 116611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF24 and examine the expression of SAMD9L. Does perturbing ZNF24 lead to a significant change in SAMD9L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF24 and examine the expression of SAMD9L. Does perturbing ZNF24 lead to a significant change in SAMD9L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 54051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP25 and examine the expression of SERINC3. Does perturbing UTP25 lead to a significant change in SERINC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP25 and examine the expression of SERINC3. Does perturbing UTP25 lead to a significant change in SERINC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 48720,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARCN1 is perturbed and the expression of PILRB is measured. Does this perturbation cause a significant change in PILRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARCN1 is perturbed and the expression of PILRB is measured. Does this perturbation cause a significant change in PILRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 95515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBLL1 is associated with a significant change in PRCP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBLL1 is associated with a significant change in PRCP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 28133,You are an expert in regulatory genomics. Consider data from K562 cells in which PFDN1 is perturbed and ERLEC1 expression is observed. Does this perturbation lead to a significant difference in ERLEC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PFDN1 is perturbed and ERLEC1 expression is observed. Does this perturbation lead to a significant difference in ERLEC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 62922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCBP1 is perturbed and PLOD2 expression is quantified. Does this perturbation result in a significant change in PLOD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCBP1 is perturbed and PLOD2 expression is quantified. Does this perturbation result in a significant change in PLOD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 69611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5PD and examine the expression of ANGPTL4. Does perturbing ATP5PD lead to a significant change in ANGPTL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5PD and examine the expression of ANGPTL4. Does perturbing ATP5PD lead to a significant change in ANGPTL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 76845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANAPC11 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANAPC11 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 35413,You are an expert in regulatory genomics. Consider data from K562 cells in which SUMO2 is perturbed and SDCCAG8 expression is observed. Does this perturbation lead to a significant difference in SDCCAG8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SUMO2 is perturbed and SDCCAG8 expression is observed. Does this perturbation lead to a significant difference in SDCCAG8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 60747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1B2, does the expression profile of TBCK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1B2, does the expression profile of TBCK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 83885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TCOF1 is associated with a significant change in ATP6AP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TCOF1 is associated with a significant change in ATP6AP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 67170,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID5B is perturbed and the expression of POLR3G is measured. Does this perturbation cause a significant change in POLR3G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID5B is perturbed and the expression of POLR3G is measured. Does this perturbation cause a significant change in POLR3G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 107328,"You are a functional genomics specialist. In K562 cells, we perturb PRDM4 and monitor ARHGEF9 expression. Decide whether this perturbation leads to a significant alteration in ARHGEF9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PRDM4 and monitor ARHGEF9 expression. Decide whether this perturbation leads to a significant alteration in ARHGEF9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 47428,"You are a functional genomics specialist. In K562 cells, we perturb ING3 and monitor BCS1L expression. Decide whether this perturbation leads to a significant alteration in BCS1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ING3 and monitor BCS1L expression. Decide whether this perturbation leads to a significant alteration in BCS1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 49426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRN3 is perturbed and the expression of BDNF is measured. Determine whether BDNF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRN3 is perturbed and the expression of BDNF is measured. Determine whether BDNF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 52201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL38 and examine the expression of FXR2. Does perturbing RPL38 lead to a significant change in FXR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL38 and examine the expression of FXR2. Does perturbing RPL38 lead to a significant change in FXR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 63900,"You are an expert in single-cell biology and functional genomics. In K562 cells, PHB2 is perturbed and the expression of TRAF3IP1 is measured. Does this perturbation cause a significant change in TRAF3IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PHB2 is perturbed and the expression of TRAF3IP1 is measured. Does this perturbation cause a significant change in TRAF3IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 112958,"You are a functional genomics specialist. In K562 cells, we perturb HIST2H2AC and monitor ALAD expression. Decide whether this perturbation leads to a significant alteration in ALAD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HIST2H2AC and monitor ALAD expression. Decide whether this perturbation leads to a significant alteration in ALAD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 26256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TWNK is perturbed and the expression of MRPS21 is measured. Determine whether MRPS21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TWNK is perturbed and the expression of MRPS21 is measured. Determine whether MRPS21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 40479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VHL is perturbed and AREL1 expression is measured. Determine whether AREL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VHL is perturbed and AREL1 expression is measured. Determine whether AREL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 65130,"You are an expert in single-cell biology and functional genomics. In K562 cells, AURKAIP1 is perturbed and the expression of PLD3 is measured. Does this perturbation cause a significant change in PLD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AURKAIP1 is perturbed and the expression of PLD3 is measured. Does this perturbation cause a significant change in PLD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 32897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCKAP1, does the expression profile of HLA-B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCKAP1, does the expression profile of HLA-B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 101571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1 and examine the expression of DESI1. Does perturbing GLB1 lead to a significant change in DESI1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1 and examine the expression of DESI1. Does perturbing GLB1 lead to a significant change in DESI1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 108118,"You are a functional genomics specialist. In K562 cells, we perturb CCDC86 and monitor UBXN7 expression. Decide whether this perturbation leads to a significant alteration in UBXN7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCDC86 and monitor UBXN7 expression. Decide whether this perturbation leads to a significant alteration in UBXN7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MALSU1 is associated with a significant change in AC037198.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MALSU1 is associated with a significant change in AC037198.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 122565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPP1CB is associated with a significant change in ZMAT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPP1CB is associated with a significant change in ZMAT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 117116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFIP11 is perturbed and the expression of PRPF3 is measured. Determine whether PRPF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFIP11 is perturbed and the expression of PRPF3 is measured. Determine whether PRPF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 107646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL29 is perturbed and the expression of ACAA1 is measured. Determine whether ACAA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL29 is perturbed and the expression of ACAA1 is measured. Determine whether ACAA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 101504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS27A and then measure expression of ITSN1. Does this perturbation cause a significant change in ITSN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS27A and then measure expression of ITSN1. Does this perturbation cause a significant change in ITSN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 46732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPH3 is perturbed and PSPH expression is quantified. Does this perturbation result in a significant change in PSPH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPH3 is perturbed and PSPH expression is quantified. Does this perturbation result in a significant change in PSPH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 38014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTC1 and then measure expression of KBTBD2. Does this perturbation cause a significant change in KBTBD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTC1 and then measure expression of KBTBD2. Does this perturbation cause a significant change in KBTBD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 59024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUBP2 and then measure expression of TMEM115. Does this perturbation cause a significant change in TMEM115 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUBP2 and then measure expression of TMEM115. Does this perturbation cause a significant change in TMEM115 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 24703,You are an expert in regulatory genomics. Consider data from K562 cells in which DDX42 is perturbed and LARP4B expression is observed. Does this perturbation lead to a significant difference in LARP4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDX42 is perturbed and LARP4B expression is observed. Does this perturbation lead to a significant difference in LARP4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 67612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CXXC1 is perturbed and RRP12 expression is quantified. Does this perturbation result in a significant change in RRP12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CXXC1 is perturbed and RRP12 expression is quantified. Does this perturbation result in a significant change in RRP12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 122837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BARD1, does the expression profile of RRAS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BARD1, does the expression profile of RRAS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 107599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPD2 is perturbed and SERINC2 expression is measured. Determine whether SERINC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPD2 is perturbed and SERINC2 expression is measured. Determine whether SERINC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAZ is perturbed and CIT expression is quantified. Does this perturbation result in a significant change in CIT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAZ is perturbed and CIT expression is quantified. Does this perturbation result in a significant change in CIT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 71352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PAK1IP1 is perturbed and PCSK1N expression is quantified. Does this perturbation result in a significant change in PCSK1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PAK1IP1 is perturbed and PCSK1N expression is quantified. Does this perturbation result in a significant change in PCSK1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 41433,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMC3 is perturbed and HPS1 expression is observed. Does this perturbation lead to a significant difference in HPS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMC3 is perturbed and HPS1 expression is observed. Does this perturbation lead to a significant difference in HPS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 24024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2F1 and then measure expression of CYBRD1. Does this perturbation cause a significant change in CYBRD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2F1 and then measure expression of CYBRD1. Does this perturbation cause a significant change in CYBRD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 40472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VHL is perturbed and AREL1 expression is quantified. Does this perturbation result in a significant change in AREL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VHL is perturbed and AREL1 expression is quantified. Does this perturbation result in a significant change in AREL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 102894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRCC6 and then measure expression of AC010642.2. Does this perturbation cause a significant change in AC010642.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRCC6 and then measure expression of AC010642.2. Does this perturbation cause a significant change in AC010642.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 68966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBA2 is perturbed and the expression of NCOA2 is measured. Determine whether NCOA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBA2 is perturbed and the expression of NCOA2 is measured. Determine whether NCOA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 25992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF31 is perturbed and NCOA7 expression is quantified. Does this perturbation result in a significant change in NCOA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF31 is perturbed and NCOA7 expression is quantified. Does this perturbation result in a significant change in NCOA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 102960,"You are an expert in single-cell biology and functional genomics. In K562 cells, RNGTT is perturbed and the expression of NABP1 is measured. Does this perturbation cause a significant change in NABP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RNGTT is perturbed and the expression of NABP1 is measured. Does this perturbation cause a significant change in NABP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 51460,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB7 is perturbed and the expression of MTOR is measured. Does this perturbation cause a significant change in MTOR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB7 is perturbed and the expression of MTOR is measured. Does this perturbation cause a significant change in MTOR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 77816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BUB1B is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BUB1B is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 76730,"You are an expert in single-cell biology and functional genomics. In K562 cells, RINT1 is perturbed and the expression of YIPF2 is measured. Does this perturbation cause a significant change in YIPF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RINT1 is perturbed and the expression of YIPF2 is measured. Does this perturbation cause a significant change in YIPF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 96365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBM48 is associated with a significant change in NDST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBM48 is associated with a significant change in NDST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 69238,"You are a functional genomics specialist. In K562 cells, we perturb DYNLL2 and monitor CDC25B expression. Decide whether this perturbation leads to a significant alteration in CDC25B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DYNLL2 and monitor CDC25B expression. Decide whether this perturbation leads to a significant alteration in CDC25B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 102570,"You are an expert in single-cell biology and functional genomics. In K562 cells, RNPS1 is perturbed and the expression of ANKRA2 is measured. Does this perturbation cause a significant change in ANKRA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RNPS1 is perturbed and the expression of ANKRA2 is measured. Does this perturbation cause a significant change in ANKRA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 22370,"You are an expert in single-cell biology and functional genomics. In K562 cells, STRAP is perturbed and the expression of HOOK3 is measured. Does this perturbation cause a significant change in HOOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STRAP is perturbed and the expression of HOOK3 is measured. Does this perturbation cause a significant change in HOOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 113951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KATNB1 and examine the expression of JARID2. Does perturbing KATNB1 lead to a significant change in JARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KATNB1 and examine the expression of JARID2. Does perturbing KATNB1 lead to a significant change in JARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 121997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTPS1, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTPS1, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 41197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM33, does the expression profile of NUP35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM33, does the expression profile of NUP35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 65840,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLNS1A is perturbed and the expression of AVL9 is measured. Does this perturbation cause a significant change in AVL9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLNS1A is perturbed and the expression of AVL9 is measured. Does this perturbation cause a significant change in AVL9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 34211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNOT3 and examine the expression of GOLPH3. Does perturbing CNOT3 lead to a significant change in GOLPH3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNOT3 and examine the expression of GOLPH3. Does perturbing CNOT3 lead to a significant change in GOLPH3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 22862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCR is perturbed and TIMM29 expression is quantified. Does this perturbation result in a significant change in TIMM29 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCR is perturbed and TIMM29 expression is quantified. Does this perturbation result in a significant change in TIMM29 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 97069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOP1 is perturbed and TMEM101 expression is measured. Determine whether TMEM101 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOP1 is perturbed and TMEM101 expression is measured. Determine whether TMEM101 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 23329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ORC6 is perturbed and P3H2 expression is measured. Determine whether P3H2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ORC6 is perturbed and P3H2 expression is measured. Determine whether P3H2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 90072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP1A1 is perturbed and IGF2BP1 expression is quantified. Does this perturbation result in a significant change in IGF2BP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP1A1 is perturbed and IGF2BP1 expression is quantified. Does this perturbation result in a significant change in IGF2BP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 108939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEN1 is perturbed and YWHAB expression is measured. Determine whether YWHAB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEN1 is perturbed and YWHAB expression is measured. Determine whether YWHAB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 32381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZFC3H1 and examine the expression of ALDH3A2. Does perturbing ZFC3H1 lead to a significant change in ALDH3A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZFC3H1 and examine the expression of ALDH3A2. Does perturbing ZFC3H1 lead to a significant change in ALDH3A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 19055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XPO5 is associated with a significant change in KPNA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XPO5 is associated with a significant change in KPNA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 79862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRAPPC4 is perturbed and KIAA0319L expression is quantified. Does this perturbation result in a significant change in KIAA0319L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRAPPC4 is perturbed and KIAA0319L expression is quantified. Does this perturbation result in a significant change in KIAA0319L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 7870,"You are an expert in single-cell biology and functional genomics. In K562 cells, IPO13 is perturbed and the expression of YDJC is measured. Does this perturbation cause a significant change in YDJC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IPO13 is perturbed and the expression of YDJC is measured. Does this perturbation cause a significant change in YDJC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 38805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFA6 is associated with a significant change in AOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFA6 is associated with a significant change in AOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 57452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SUDS3 is perturbed and ABI1 expression is quantified. Does this perturbation result in a significant change in ABI1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SUDS3 is perturbed and ABI1 expression is quantified. Does this perturbation result in a significant change in ABI1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FBXO30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FBXO30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 60425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOL6 is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOL6 is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 52885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM5 is associated with a significant change in ZNF322 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM5 is associated with a significant change in ZNF322 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 74135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPTF is associated with a significant change in COQ4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPTF is associated with a significant change in COQ4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 68720,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4A3 is perturbed and the expression of ZNF384 is measured. Does this perturbation cause a significant change in ZNF384 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4A3 is perturbed and the expression of ZNF384 is measured. Does this perturbation cause a significant change in ZNF384 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KDM2A and then measure expression of CFAP298. Does this perturbation cause a significant change in CFAP298 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KDM2A and then measure expression of CFAP298. Does this perturbation cause a significant change in CFAP298 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 123492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3F is perturbed and MXRA7 expression is quantified. Does this perturbation result in a significant change in MXRA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3F is perturbed and MXRA7 expression is quantified. Does this perturbation result in a significant change in MXRA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 28828,"You are a functional genomics specialist. In K562 cells, we perturb SDHA and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SDHA and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 45754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPR and then measure expression of CIR1. Does this perturbation cause a significant change in CIR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPR and then measure expression of CIR1. Does this perturbation cause a significant change in CIR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 36762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ABHD11 is perturbed and ROCK1 expression is quantified. Does this perturbation result in a significant change in ROCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ABHD11 is perturbed and ROCK1 expression is quantified. Does this perturbation result in a significant change in ROCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 85261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN2 and examine the expression of MDM2. Does perturbing XRN2 lead to a significant change in MDM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN2 and examine the expression of MDM2. Does perturbing XRN2 lead to a significant change in MDM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 111050,"You are an expert in single-cell biology and functional genomics. In K562 cells, LDB1 is perturbed and the expression of AASS is measured. Does this perturbation cause a significant change in AASS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LDB1 is perturbed and the expression of AASS is measured. Does this perturbation cause a significant change in AASS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 122604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR55 and then measure expression of TNC. Does this perturbation cause a significant change in TNC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR55 and then measure expression of TNC. Does this perturbation cause a significant change in TNC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 29034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TPT1 and then measure expression of TMEM50B. Does this perturbation cause a significant change in TMEM50B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TPT1 and then measure expression of TMEM50B. Does this perturbation cause a significant change in TMEM50B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 113110,"You are an expert in single-cell biology and functional genomics. In K562 cells, SKA3 is perturbed and the expression of SUGCT is measured. Does this perturbation cause a significant change in SUGCT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SKA3 is perturbed and the expression of SUGCT is measured. Does this perturbation cause a significant change in SUGCT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 78612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NFYB is perturbed and IFI27L2 expression is quantified. Does this perturbation result in a significant change in IFI27L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NFYB is perturbed and IFI27L2 expression is quantified. Does this perturbation result in a significant change in IFI27L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 105274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP152 and then measure expression of FCF1. Does this perturbation cause a significant change in FCF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP152 and then measure expression of FCF1. Does this perturbation cause a significant change in FCF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 27673,You are an expert in regulatory genomics. Consider data from K562 cells in which COPS6 is perturbed and IDI1 expression is observed. Does this perturbation lead to a significant difference in IDI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPS6 is perturbed and IDI1 expression is observed. Does this perturbation lead to a significant difference in IDI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 66864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL17 and then measure expression of NDUFS2. Does this perturbation cause a significant change in NDUFS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL17 and then measure expression of NDUFS2. Does this perturbation cause a significant change in NDUFS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 123616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCT5 is perturbed and the expression of SELENOM is measured. Determine whether SELENOM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCT5 is perturbed and the expression of SELENOM is measured. Determine whether SELENOM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 101831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHMP7 and examine the expression of HSD17B11. Does perturbing CHMP7 lead to a significant change in HSD17B11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHMP7 and examine the expression of HSD17B11. Does perturbing CHMP7 lead to a significant change in HSD17B11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 95146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC3 is perturbed and the expression of IFT52 is measured. Determine whether IFT52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC3 is perturbed and the expression of IFT52 is measured. Determine whether IFT52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 77881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS11 and examine the expression of ZIM3. Does perturbing RPS11 lead to a significant change in ZIM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS11 and examine the expression of ZIM3. Does perturbing RPS11 lead to a significant change in ZIM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 97260,"You are an expert in single-cell biology and functional genomics. In K562 cells, USPL1 is perturbed and the expression of CREB1 is measured. Does this perturbation cause a significant change in CREB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, USPL1 is perturbed and the expression of CREB1 is measured. Does this perturbation cause a significant change in CREB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 42589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V0C is perturbed and NNMT expression is measured. Determine whether NNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V0C is perturbed and NNMT expression is measured. Determine whether NNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 16612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM258 is perturbed and CISD2 expression is quantified. Does this perturbation result in a significant change in CISD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM258 is perturbed and CISD2 expression is quantified. Does this perturbation result in a significant change in CISD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 81121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDPK1 and examine the expression of AKAP9. Does perturbing PDPK1 lead to a significant change in AKAP9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDPK1 and examine the expression of AKAP9. Does perturbing PDPK1 lead to a significant change in AKAP9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 31757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPME1, does the expression profile of ANGPTL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPME1, does the expression profile of ANGPTL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 12547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COX17, does the expression profile of ACER3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COX17, does the expression profile of ACER3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 107250,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCNL1 is perturbed and the expression of OGFOD1 is measured. Does this perturbation cause a significant change in OGFOD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCNL1 is perturbed and the expression of OGFOD1 is measured. Does this perturbation cause a significant change in OGFOD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 46909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHORDC1 is perturbed and SNHG14 expression is measured. Determine whether SNHG14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHORDC1 is perturbed and SNHG14 expression is measured. Determine whether SNHG14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FBXO42 is perturbed and the expression of EEPD1 is measured. Determine whether EEPD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FBXO42 is perturbed and the expression of EEPD1 is measured. Determine whether EEPD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 103528,"You are a functional genomics specialist. In K562 cells, we perturb TOP3A and monitor SLC30A5 expression. Decide whether this perturbation leads to a significant alteration in SLC30A5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TOP3A and monitor SLC30A5 expression. Decide whether this perturbation leads to a significant alteration in SLC30A5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 76285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PIK3C3 is associated with a significant change in TRIM8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PIK3C3 is associated with a significant change in TRIM8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 64842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2N is perturbed and GFER expression is quantified. Does this perturbation result in a significant change in GFER expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2N is perturbed and GFER expression is quantified. Does this perturbation result in a significant change in GFER expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 74315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM9 is associated with a significant change in TRMT61A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM9 is associated with a significant change in TRMT61A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 21363,You are an expert in regulatory genomics. Consider data from K562 cells in which CAPZB is perturbed and NIPSNAP3A expression is observed. Does this perturbation lead to a significant difference in NIPSNAP3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CAPZB is perturbed and NIPSNAP3A expression is observed. Does this perturbation lead to a significant difference in NIPSNAP3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 31137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USP14, does the expression profile of AC093673.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USP14, does the expression profile of AC093673.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 45442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBPL1 is perturbed and HCFC2 expression is quantified. Does this perturbation result in a significant change in HCFC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBPL1 is perturbed and HCFC2 expression is quantified. Does this perturbation result in a significant change in HCFC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 11778,"You are a functional genomics specialist. In K562 cells, we perturb RBBP4 and monitor ODF2 expression. Decide whether this perturbation leads to a significant alteration in ODF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RBBP4 and monitor ODF2 expression. Decide whether this perturbation leads to a significant alteration in ODF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 33790,"You are an expert in single-cell biology and functional genomics. In K562 cells, CACNB3 is perturbed and the expression of CC2D1A is measured. Does this perturbation cause a significant change in CC2D1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CACNB3 is perturbed and the expression of CC2D1A is measured. Does this perturbation cause a significant change in CC2D1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 62906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCBP1 is perturbed and the expression of RANGRF is measured. Determine whether RANGRF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCBP1 is perturbed and the expression of RANGRF is measured. Determine whether RANGRF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 119565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPC is associated with a significant change in HOOK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPC is associated with a significant change in HOOK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 109809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTL6A is perturbed and EXT1 expression is measured. Determine whether EXT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTL6A is perturbed and EXT1 expression is measured. Determine whether EXT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 79517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL55, does the expression profile of MFN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL55, does the expression profile of MFN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 48247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNHIT3, does the expression profile of ZDHHC8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNHIT3, does the expression profile of ZDHHC8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 79263,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B1 is perturbed and CCPG1 expression is observed. Does this perturbation lead to a significant difference in CCPG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B1 is perturbed and CCPG1 expression is observed. Does this perturbation lead to a significant difference in CCPG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 8141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3A2 and examine the expression of ORAI3. Does perturbing SF3A2 lead to a significant change in ORAI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3A2 and examine the expression of ORAI3. Does perturbing SF3A2 lead to a significant change in ORAI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 68593,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB2 is perturbed and GMEB1 expression is observed. Does this perturbation lead to a significant difference in GMEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB2 is perturbed and GMEB1 expression is observed. Does this perturbation lead to a significant difference in GMEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 18500,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of TNIP1 is measured. Does this perturbation cause a significant change in TNIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of TNIP1 is measured. Does this perturbation cause a significant change in TNIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 13856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of TNFRSF10D is measured. Determine whether TNFRSF10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of TNFRSF10D is measured. Determine whether TNFRSF10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 94159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLR3A is perturbed and XBP1 expression is measured. Determine whether XBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLR3A is perturbed and XBP1 expression is measured. Determine whether XBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 60694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RAE1 and then measure expression of ETFDH. Does this perturbation cause a significant change in ETFDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RAE1 and then measure expression of ETFDH. Does this perturbation cause a significant change in ETFDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 18579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XAB2 is perturbed and FGFR1OP2 expression is measured. Determine whether FGFR1OP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XAB2 is perturbed and FGFR1OP2 expression is measured. Determine whether FGFR1OP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 88917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFA8, does the expression profile of ABL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFA8, does the expression profile of ABL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 76447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPAP1, does the expression profile of DCTN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPAP1, does the expression profile of DCTN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 99340,"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of REPS1 is measured. Does this perturbation cause a significant change in REPS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of REPS1 is measured. Does this perturbation cause a significant change in REPS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2480,"You are an expert in single-cell biology and functional genomics. In K562 cells, N6AMT1 is perturbed and the expression of SMAP1 is measured. Does this perturbation cause a significant change in SMAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, N6AMT1 is perturbed and the expression of SMAP1 is measured. Does this perturbation cause a significant change in SMAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 16051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3B5 and examine the expression of SNHG32. Does perturbing SF3B5 lead to a significant change in SNHG32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3B5 and examine the expression of SNHG32. Does perturbing SF3B5 lead to a significant change in SNHG32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 37318,"You are a functional genomics specialist. In K562 cells, we perturb PARN and monitor PLOD3 expression. Decide whether this perturbation leads to a significant alteration in PLOD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PARN and monitor PLOD3 expression. Decide whether this perturbation leads to a significant alteration in PLOD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 107183,You are an expert in regulatory genomics. Consider data from K562 cells in which AQR is perturbed and TMCC3 expression is observed. Does this perturbation lead to a significant difference in TMCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AQR is perturbed and TMCC3 expression is observed. Does this perturbation lead to a significant difference in TMCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2438,"You are a functional genomics specialist. In K562 cells, we perturb N6AMT1 and monitor PPP6R3 expression. Decide whether this perturbation leads to a significant alteration in PPP6R3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb N6AMT1 and monitor PPP6R3 expression. Decide whether this perturbation leads to a significant alteration in PPP6R3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 103892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIPIN is perturbed and THOC5 expression is quantified. Does this perturbation result in a significant change in THOC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIPIN is perturbed and THOC5 expression is quantified. Does this perturbation result in a significant change in THOC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 70039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NFATC2IP is perturbed and TTC17 expression is measured. Determine whether TTC17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NFATC2IP is perturbed and TTC17 expression is measured. Determine whether TTC17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 117846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABCB7 is perturbed and the expression of KMT5B is measured. Determine whether KMT5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABCB7 is perturbed and the expression of KMT5B is measured. Determine whether KMT5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 70405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF4 is associated with a significant change in RPRD1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF4 is associated with a significant change in RPRD1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 114726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZRANB2 is perturbed and the expression of SUPV3L1 is measured. Determine whether SUPV3L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZRANB2 is perturbed and the expression of SUPV3L1 is measured. Determine whether SUPV3L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 13439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS6 is perturbed and CFAP36 expression is measured. Determine whether CFAP36 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS6 is perturbed and CFAP36 expression is measured. Determine whether CFAP36 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 115955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AGBL5 is associated with a significant change in AC027031.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AGBL5 is associated with a significant change in AC027031.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 32024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMG1 and then measure expression of ANAPC16. Does this perturbation cause a significant change in ANAPC16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMG1 and then measure expression of ANAPC16. Does this perturbation cause a significant change in ANAPC16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 62869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PNN is perturbed and SLC17A5 expression is measured. Determine whether SLC17A5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PNN is perturbed and SLC17A5 expression is measured. Determine whether SLC17A5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 86865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A9 is associated with a significant change in RAB11B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A9 is associated with a significant change in RAB11B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 58958,"You are a functional genomics specialist. In K562 cells, we perturb ARPC1B and monitor ARHGAP29 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARPC1B and monitor ARHGAP29 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 114299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TONSL is perturbed and MARK4 expression is measured. Determine whether MARK4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TONSL is perturbed and MARK4 expression is measured. Determine whether MARK4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 8737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS11, does the expression profile of CA9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS11, does the expression profile of CA9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 79687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDR3, does the expression profile of TFPI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDR3, does the expression profile of TFPI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 86264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PCF11 and then measure expression of AK1. Does this perturbation cause a significant change in AK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PCF11 and then measure expression of AK1. Does this perturbation cause a significant change in AK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 18399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YRDC is perturbed and RPIA expression is measured. Determine whether RPIA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YRDC is perturbed and RPIA expression is measured. Determine whether RPIA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 10461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHPS and examine the expression of RAPH1. Does perturbing DHPS lead to a significant change in RAPH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHPS and examine the expression of RAPH1. Does perturbing DHPS lead to a significant change in RAPH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 11507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of LURAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of LURAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 105660,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPB is perturbed and the expression of KCNK6 is measured. Does this perturbation cause a significant change in KCNK6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPB is perturbed and the expression of KCNK6 is measured. Does this perturbation cause a significant change in KCNK6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 13403,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS6 is perturbed and LRRC40 expression is observed. Does this perturbation lead to a significant difference in LRRC40 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS6 is perturbed and LRRC40 expression is observed. Does this perturbation lead to a significant difference in LRRC40 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 65547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IPO11, does the expression profile of CLTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IPO11, does the expression profile of CLTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 22393,You are an expert in regulatory genomics. Consider data from K562 cells in which HLA-C is perturbed and FKBP5 expression is observed. Does this perturbation lead to a significant difference in FKBP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HLA-C is perturbed and FKBP5 expression is observed. Does this perturbation lead to a significant difference in FKBP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 92096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF1B is perturbed and the expression of SDF2 is measured. Determine whether SDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF1B is perturbed and the expression of SDF2 is measured. Determine whether SDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 35869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PAXBP1 is perturbed and KIAA2026 expression is measured. Determine whether KIAA2026 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PAXBP1 is perturbed and KIAA2026 expression is measured. Determine whether KIAA2026 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 84464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SFSWAP and then measure expression of FLYWCH1. Does this perturbation cause a significant change in FLYWCH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SFSWAP and then measure expression of FLYWCH1. Does this perturbation cause a significant change in FLYWCH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 20662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLC2 is perturbed and SMG6 expression is quantified. Does this perturbation result in a significant change in SMG6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLC2 is perturbed and SMG6 expression is quantified. Does this perturbation result in a significant change in SMG6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 21314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAPZB and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAPZB and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 16074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SF3B5 and then measure expression of NADSYN1. Does this perturbation cause a significant change in NADSYN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SF3B5 and then measure expression of NADSYN1. Does this perturbation cause a significant change in NADSYN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 58183,You are an expert in regulatory genomics. Consider data from K562 cells in which MKRN1 is perturbed and PPIF expression is observed. Does this perturbation lead to a significant difference in PPIF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MKRN1 is perturbed and PPIF expression is observed. Does this perturbation lead to a significant difference in PPIF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 103072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ITGA11 expression is quantified. Does this perturbation result in a significant change in ITGA11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ITGA11 expression is quantified. Does this perturbation result in a significant change in ITGA11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 48528,"You are a functional genomics specialist. In K562 cells, we perturb CDK11A and monitor DDX19A expression. Decide whether this perturbation leads to a significant alteration in DDX19A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDK11A and monitor DDX19A expression. Decide whether this perturbation leads to a significant alteration in DDX19A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 15178,"You are a functional genomics specialist. In K562 cells, we perturb COG8 and monitor RRAS expression. Decide whether this perturbation leads to a significant alteration in RRAS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COG8 and monitor RRAS expression. Decide whether this perturbation leads to a significant alteration in RRAS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 36441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NDUFA3 and examine the expression of SNHG8. Does perturbing NDUFA3 lead to a significant change in SNHG8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NDUFA3 and examine the expression of SNHG8. Does perturbing NDUFA3 lead to a significant change in SNHG8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 88896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR70 is perturbed and the expression of ASB3 is measured. Determine whether ASB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR70 is perturbed and the expression of ASB3 is measured. Determine whether ASB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 55972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3E is perturbed and PIM3 expression is quantified. Does this perturbation result in a significant change in PIM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3E is perturbed and PIM3 expression is quantified. Does this perturbation result in a significant change in PIM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 68124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UQCRB and then measure expression of KRIT1. Does this perturbation cause a significant change in KRIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UQCRB and then measure expression of KRIT1. Does this perturbation cause a significant change in KRIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 99582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFB3 is perturbed and ZNF675 expression is quantified. Does this perturbation result in a significant change in ZNF675 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFB3 is perturbed and ZNF675 expression is quantified. Does this perturbation result in a significant change in ZNF675 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 56999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL4 is perturbed and STRADA expression is measured. Determine whether STRADA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL4 is perturbed and STRADA expression is measured. Determine whether STRADA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 35042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1143 is perturbed and SMC5 expression is quantified. Does this perturbation result in a significant change in SMC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1143 is perturbed and SMC5 expression is quantified. Does this perturbation result in a significant change in SMC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 20472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KPNB1 is perturbed and LAMB2 expression is quantified. Does this perturbation result in a significant change in LAMB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KPNB1 is perturbed and LAMB2 expression is quantified. Does this perturbation result in a significant change in LAMB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 45859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSNK1A1 is perturbed and HMG20B expression is measured. Determine whether HMG20B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSNK1A1 is perturbed and HMG20B expression is measured. Determine whether HMG20B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 104300,"You are an expert in single-cell biology and functional genomics. In K562 cells, RAD17 is perturbed and the expression of GLRX is measured. Does this perturbation cause a significant change in GLRX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RAD17 is perturbed and the expression of GLRX is measured. Does this perturbation cause a significant change in GLRX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 47686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SUGP1 is perturbed and the expression of XYLT1 is measured. Determine whether XYLT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SUGP1 is perturbed and the expression of XYLT1 is measured. Determine whether XYLT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 84336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TXNL4A is perturbed and the expression of ANXA3 is measured. Determine whether ANXA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TXNL4A is perturbed and the expression of ANXA3 is measured. Determine whether ANXA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 24095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in ST7L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in ST7L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 53449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4G2 is perturbed and HSF2BP expression is measured. Determine whether HSF2BP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4G2 is perturbed and HSF2BP expression is measured. Determine whether HSF2BP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 115108,"You are a functional genomics specialist. In K562 cells, we perturb PPP1R15B and monitor CHCHD6 expression. Decide whether this perturbation leads to a significant alteration in CHCHD6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PPP1R15B and monitor CHCHD6 expression. Decide whether this perturbation leads to a significant alteration in CHCHD6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 9558,"You are a functional genomics specialist. In K562 cells, we perturb MFAP1 and monitor ZCCHC24 expression. Decide whether this perturbation leads to a significant alteration in ZCCHC24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MFAP1 and monitor ZCCHC24 expression. Decide whether this perturbation leads to a significant alteration in ZCCHC24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 7885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRF1 is associated with a significant change in SRGAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRF1 is associated with a significant change in SRGAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 30500,"You are an expert in single-cell biology and functional genomics. In K562 cells, RNPC3 is perturbed and the expression of PPP1R14B-AS1 is measured. Does this perturbation cause a significant change in PPP1R14B-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RNPC3 is perturbed and the expression of PPP1R14B-AS1 is measured. Does this perturbation cause a significant change in PPP1R14B-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 37444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPK and then measure expression of MXI1. Does this perturbation cause a significant change in MXI1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPK and then measure expression of MXI1. Does this perturbation cause a significant change in MXI1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 23372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLTC is perturbed and GNPTAB expression is quantified. Does this perturbation result in a significant change in GNPTAB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLTC is perturbed and GNPTAB expression is quantified. Does this perturbation result in a significant change in GNPTAB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 33796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CACNB3 is perturbed and the expression of CC2D1A is measured. Determine whether CC2D1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CACNB3 is perturbed and the expression of CC2D1A is measured. Determine whether CC2D1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 78139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NOC4L is perturbed and CDC73 expression is measured. Determine whether CDC73 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NOC4L is perturbed and CDC73 expression is measured. Determine whether CDC73 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 105941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR18 and examine the expression of PGM3. Does perturbing WDR18 lead to a significant change in PGM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR18 and examine the expression of PGM3. Does perturbing WDR18 lead to a significant change in PGM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 77408,"You are a functional genomics specialist. In K562 cells, we perturb RCC1 and monitor SESN1 expression. Decide whether this perturbation leads to a significant alteration in SESN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RCC1 and monitor SESN1 expression. Decide whether this perturbation leads to a significant alteration in SESN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 100245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCTN4 is associated with a significant change in IBTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCTN4 is associated with a significant change in IBTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 31997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMG1, does the expression profile of DCPS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMG1, does the expression profile of DCPS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 20681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLC2 and examine the expression of PRRX1. Does perturbing KLC2 lead to a significant change in PRRX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLC2 and examine the expression of PRRX1. Does perturbing KLC2 lead to a significant change in PRRX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 47664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COASY and then measure expression of KATNB1. Does this perturbation cause a significant change in KATNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COASY and then measure expression of KATNB1. Does this perturbation cause a significant change in KATNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 95035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX11 is associated with a significant change in WWC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX11 is associated with a significant change in WWC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 100873,You are an expert in regulatory genomics. Consider data from K562 cells in which MIS12 is perturbed and TERF2IP expression is observed. Does this perturbation lead to a significant difference in TERF2IP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MIS12 is perturbed and TERF2IP expression is observed. Does this perturbation lead to a significant difference in TERF2IP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 103830,"You are an expert in single-cell biology and functional genomics. In K562 cells, PNO1 is perturbed and the expression of PIP4K2B is measured. Does this perturbation cause a significant change in PIP4K2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PNO1 is perturbed and the expression of PIP4K2B is measured. Does this perturbation cause a significant change in PIP4K2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 45817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSNK1A1, does the expression profile of SNHG32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSNK1A1, does the expression profile of SNHG32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 57349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CENPI is perturbed and ME3 expression is measured. Determine whether ME3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CENPI is perturbed and ME3 expression is measured. Determine whether ME3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 95262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CMTR1 is perturbed and TBC1D5 expression is quantified. Does this perturbation result in a significant change in TBC1D5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CMTR1 is perturbed and TBC1D5 expression is quantified. Does this perturbation result in a significant change in TBC1D5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 101214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC2 and then measure expression of PITHD1. Does this perturbation cause a significant change in PITHD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC2 and then measure expression of PITHD1. Does this perturbation cause a significant change in PITHD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 111417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNRD1, does the expression profile of MYADM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNRD1, does the expression profile of MYADM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 37549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STRIP1 is perturbed and KRT18 expression is measured. Determine whether KRT18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STRIP1 is perturbed and KRT18 expression is measured. Determine whether KRT18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 74430,"You are an expert in single-cell biology and functional genomics. In K562 cells, ERCC2 is perturbed and the expression of SNX3 is measured. Does this perturbation cause a significant change in SNX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ERCC2 is perturbed and the expression of SNX3 is measured. Does this perturbation cause a significant change in SNX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 15253,You are an expert in regulatory genomics. Consider data from K562 cells in which COG3 is perturbed and MPLKIP expression is observed. Does this perturbation lead to a significant difference in MPLKIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COG3 is perturbed and MPLKIP expression is observed. Does this perturbation lead to a significant difference in MPLKIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 81619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALG1 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALG1 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 86541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPE and examine the expression of SZT2. Does perturbing CENPE lead to a significant change in SZT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPE and examine the expression of SZT2. Does perturbing CENPE lead to a significant change in SZT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 84025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HPS5 is associated with a significant change in FAM126A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HPS5 is associated with a significant change in FAM126A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 104713,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF23 is perturbed and RPS6KB2 expression is observed. Does this perturbation lead to a significant difference in RPS6KB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF23 is perturbed and RPS6KB2 expression is observed. Does this perturbation lead to a significant difference in RPS6KB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 73373,You are an expert in regulatory genomics. Consider data from K562 cells in which GUCD1 is perturbed and GPC1 expression is observed. Does this perturbation lead to a significant difference in GPC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GUCD1 is perturbed and GPC1 expression is observed. Does this perturbation lead to a significant difference in GPC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 116705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DMAP1 is associated with a significant change in PLAC9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DMAP1 is associated with a significant change in PLAC9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 38361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBE1 and examine the expression of SEMA5A. Does perturbing TUBE1 lead to a significant change in SEMA5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBE1 and examine the expression of SEMA5A. Does perturbing TUBE1 lead to a significant change in SEMA5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 83205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC115 is associated with a significant change in TCEA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC115 is associated with a significant change in TCEA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 13704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS18B and then measure expression of LYRM1. Does this perturbation cause a significant change in LYRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS18B and then measure expression of LYRM1. Does this perturbation cause a significant change in LYRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 91371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of FGF2. Does perturbing EIF2B2 lead to a significant change in FGF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of FGF2. Does perturbing EIF2B2 lead to a significant change in FGF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 77191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LONP1 and examine the expression of FHL2. Does perturbing LONP1 lead to a significant change in FHL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LONP1 and examine the expression of FHL2. Does perturbing LONP1 lead to a significant change in FHL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 52266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R10 is perturbed and the expression of SH3BGRL is measured. Determine whether SH3BGRL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R10 is perturbed and the expression of SH3BGRL is measured. Determine whether SH3BGRL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5220,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP6 is perturbed and the expression of TUBA4A is measured. Does this perturbation cause a significant change in TUBA4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP6 is perturbed and the expression of TUBA4A is measured. Does this perturbation cause a significant change in TUBA4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 33833,You are an expert in regulatory genomics. Consider data from K562 cells in which CACNB3 is perturbed and RPARP-AS1 expression is observed. Does this perturbation lead to a significant difference in RPARP-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CACNB3 is perturbed and RPARP-AS1 expression is observed. Does this perturbation lead to a significant difference in RPARP-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 77989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SMARCC1 is perturbed and PDLIM7 expression is measured. Determine whether PDLIM7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SMARCC1 is perturbed and PDLIM7 expression is measured. Determine whether PDLIM7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 24618,"You are a functional genomics specialist. In K562 cells, we perturb SNRPD3 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SNRPD3 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 15513,You are an expert in regulatory genomics. Consider data from K562 cells in which PAF1 is perturbed and TSPAN14 expression is observed. Does this perturbation lead to a significant difference in TSPAN14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PAF1 is perturbed and TSPAN14 expression is observed. Does this perturbation lead to a significant difference in TSPAN14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 15212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COG3 is perturbed and PMEPA1 expression is quantified. Does this perturbation result in a significant change in PMEPA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COG3 is perturbed and PMEPA1 expression is quantified. Does this perturbation result in a significant change in PMEPA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 55051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF4A and examine the expression of ORC5. Does perturbing KIF4A lead to a significant change in ORC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF4A and examine the expression of ORC5. Does perturbing KIF4A lead to a significant change in ORC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 79917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LAMTOR3, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LAMTOR3, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 84003,You are an expert in regulatory genomics. Consider data from K562 cells in which HPS5 is perturbed and MAN2A1 expression is observed. Does this perturbation lead to a significant difference in MAN2A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HPS5 is perturbed and MAN2A1 expression is observed. Does this perturbation lead to a significant difference in MAN2A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 49892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5F1B is perturbed and VPS37A expression is quantified. Does this perturbation result in a significant change in VPS37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5F1B is perturbed and VPS37A expression is quantified. Does this perturbation result in a significant change in VPS37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 112788,"You are a functional genomics specialist. In K562 cells, we perturb ATP6V1E1 and monitor CEP44 expression. Decide whether this perturbation leads to a significant alteration in CEP44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ATP6V1E1 and monitor CEP44 expression. Decide whether this perturbation leads to a significant alteration in CEP44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 68076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC2 is perturbed and the expression of SMIM27 is measured. Determine whether SMIM27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC2 is perturbed and the expression of SMIM27 is measured. Determine whether SMIM27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 99330,"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of TANC2 is measured. Does this perturbation cause a significant change in TANC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of TANC2 is measured. Does this perturbation cause a significant change in TANC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 87769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOD2 is perturbed and OCRL expression is measured. Determine whether OCRL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOD2 is perturbed and OCRL expression is measured. Determine whether OCRL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 114749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZRANB2 is perturbed and MTMR1 expression is measured. Determine whether MTMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZRANB2 is perturbed and MTMR1 expression is measured. Determine whether MTMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 104466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX41 is perturbed and the expression of DCAF10 is measured. Determine whether DCAF10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX41 is perturbed and the expression of DCAF10 is measured. Determine whether DCAF10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 100651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNMT1 and examine the expression of ATP10D. Does perturbing DNMT1 lead to a significant change in ATP10D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNMT1 and examine the expression of ATP10D. Does perturbing DNMT1 lead to a significant change in ATP10D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 620,"You are an expert in single-cell biology and functional genomics. In K562 cells, LIMS1 is perturbed and the expression of FPGS is measured. Does this perturbation cause a significant change in FPGS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LIMS1 is perturbed and the expression of FPGS is measured. Does this perturbation cause a significant change in FPGS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 26178,"You are a functional genomics specialist. In K562 cells, we perturb ACTR10 and monitor JAG1 expression. Decide whether this perturbation leads to a significant alteration in JAG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ACTR10 and monitor JAG1 expression. Decide whether this perturbation leads to a significant alteration in JAG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 45535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF18 is associated with a significant change in HSBP1L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF18 is associated with a significant change in HSBP1L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 113378,"You are a functional genomics specialist. In K562 cells, we perturb AURKA and monitor RPGRIP1L expression. Decide whether this perturbation leads to a significant alteration in RPGRIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AURKA and monitor RPGRIP1L expression. Decide whether this perturbation leads to a significant alteration in RPGRIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 85965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCMF1 is associated with a significant change in PAXX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCMF1 is associated with a significant change in PAXX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 54575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR3H is associated with a significant change in PPP1R11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR3H is associated with a significant change in PPP1R11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 97080,"You are an expert in single-cell biology and functional genomics. In K562 cells, CINP is perturbed and the expression of CCNG1 is measured. Does this perturbation cause a significant change in CCNG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CINP is perturbed and the expression of CCNG1 is measured. Does this perturbation cause a significant change in CCNG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 19135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLI4 is associated with a significant change in SDF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLI4 is associated with a significant change in SDF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 112440,"You are an expert in single-cell biology and functional genomics. In K562 cells, MSL1 is perturbed and the expression of LTBP4 is measured. Does this perturbation cause a significant change in LTBP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MSL1 is perturbed and the expression of LTBP4 is measured. Does this perturbation cause a significant change in LTBP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 7228,"You are a functional genomics specialist. In K562 cells, we perturb MYBL2 and monitor MRPL1 expression. Decide whether this perturbation leads to a significant alteration in MRPL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MYBL2 and monitor MRPL1 expression. Decide whether this perturbation leads to a significant alteration in MRPL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 56155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TFDP1 is associated with a significant change in SLC35D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TFDP1 is associated with a significant change in SLC35D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 91921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DPAGT1 and examine the expression of SOD2. Does perturbing DPAGT1 lead to a significant change in SOD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DPAGT1 and examine the expression of SOD2. Does perturbing DPAGT1 lead to a significant change in SOD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 103933,You are an expert in regulatory genomics. Consider data from K562 cells in which DUT is perturbed and WASHC2A expression is observed. Does this perturbation lead to a significant difference in WASHC2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DUT is perturbed and WASHC2A expression is observed. Does this perturbation lead to a significant difference in WASHC2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 113944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KATNB1 and then measure expression of PLAT. Does this perturbation cause a significant change in PLAT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KATNB1 and then measure expression of PLAT. Does this perturbation cause a significant change in PLAT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 9535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MFAP1 is associated with a significant change in NT5DC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MFAP1 is associated with a significant change in NT5DC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 40599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALYREF is perturbed and ANXA6 expression is measured. Determine whether ANXA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALYREF is perturbed and ANXA6 expression is measured. Determine whether ANXA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 64870,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPUSD3 is perturbed and the expression of GPC1 is measured. Does this perturbation cause a significant change in GPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPUSD3 is perturbed and the expression of GPC1 is measured. Does this perturbation cause a significant change in GPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 112835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISG20L2 is associated with a significant change in MYEOV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISG20L2 is associated with a significant change in MYEOV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 40164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TCERG1 and then measure expression of COPZ2. Does this perturbation cause a significant change in COPZ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TCERG1 and then measure expression of COPZ2. Does this perturbation cause a significant change in COPZ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 93771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CTU2 and examine the expression of SMIM29. Does perturbing CTU2 lead to a significant change in SMIM29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CTU2 and examine the expression of SMIM29. Does perturbing CTU2 lead to a significant change in SMIM29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 24354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POGLUT3 and then measure expression of PSMB7. Does this perturbation cause a significant change in PSMB7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POGLUT3 and then measure expression of PSMB7. Does this perturbation cause a significant change in PSMB7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 34661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb USP10 and examine the expression of GNAI1. Does perturbing USP10 lead to a significant change in GNAI1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb USP10 and examine the expression of GNAI1. Does perturbing USP10 lead to a significant change in GNAI1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 41070,"You are an expert in single-cell biology and functional genomics. In K562 cells, KDM1A is perturbed and the expression of RAB22A is measured. Does this perturbation cause a significant change in RAB22A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KDM1A is perturbed and the expression of RAB22A is measured. Does this perturbation cause a significant change in RAB22A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 47144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP97 and then measure expression of PEX2. Does this perturbation cause a significant change in PEX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP97 and then measure expression of PEX2. Does this perturbation cause a significant change in PEX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 18195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KDM6A is associated with a significant change in WWTR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KDM6A is associated with a significant change in WWTR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 35252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSME1 is perturbed and PPP6R2 expression is quantified. Does this perturbation result in a significant change in PPP6R2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSME1 is perturbed and PPP6R2 expression is quantified. Does this perturbation result in a significant change in PPP6R2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 29838,"You are a functional genomics specialist. In K562 cells, we perturb ENO1 and monitor LINC02802 expression. Decide whether this perturbation leads to a significant alteration in LINC02802 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ENO1 and monitor LINC02802 expression. Decide whether this perturbation leads to a significant alteration in LINC02802 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 118092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FXN is perturbed and GREM1 expression is quantified. Does this perturbation result in a significant change in GREM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FXN is perturbed and GREM1 expression is quantified. Does this perturbation result in a significant change in GREM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 19607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNK, does the expression profile of SAYSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNK, does the expression profile of SAYSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 78885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPC is associated with a significant change in PLBD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPC is associated with a significant change in PLBD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 82070,"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD2 is perturbed and the expression of ACTA2 is measured. Does this perturbation cause a significant change in ACTA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD2 is perturbed and the expression of ACTA2 is measured. Does this perturbation cause a significant change in ACTA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 23128,"You are a functional genomics specialist. In K562 cells, we perturb SHC1 and monitor GDF11 expression. Decide whether this perturbation leads to a significant alteration in GDF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SHC1 and monitor GDF11 expression. Decide whether this perturbation leads to a significant alteration in GDF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 73819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC17 is perturbed and CTDP1 expression is measured. Determine whether CTDP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC17 is perturbed and CTDP1 expression is measured. Determine whether CTDP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 47547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GOSR2, does the expression profile of TMUB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GOSR2, does the expression profile of TMUB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 43624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2R3C and then measure expression of LEPROTL1. Does this perturbation cause a significant change in LEPROTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2R3C and then measure expression of LEPROTL1. Does this perturbation cause a significant change in LEPROTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 38792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFA6 is perturbed and NOC3L expression is quantified. Does this perturbation result in a significant change in NOC3L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFA6 is perturbed and NOC3L expression is quantified. Does this perturbation result in a significant change in NOC3L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 56033,You are an expert in regulatory genomics. Consider data from K562 cells in which STAG2 is perturbed and ZFPM1 expression is observed. Does this perturbation lead to a significant difference in ZFPM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STAG2 is perturbed and ZFPM1 expression is observed. Does this perturbation lead to a significant difference in ZFPM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 123591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of CAPZB. Does perturbing CCT5 lead to a significant change in CAPZB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of CAPZB. Does perturbing CCT5 lead to a significant change in CAPZB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 29669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS30 is perturbed and ZNF581 expression is measured. Determine whether ZNF581 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS30 is perturbed and ZNF581 expression is measured. Determine whether ZNF581 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 100955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNF168 is associated with a significant change in SEC16A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNF168 is associated with a significant change in SEC16A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 71245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NLE1 is associated with a significant change in D2HGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NLE1 is associated with a significant change in D2HGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 35628,"You are a functional genomics specialist. In K562 cells, we perturb FYN and monitor ATP6V1B2 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1B2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FYN and monitor ATP6V1B2 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1B2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 11934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPS and then measure expression of GNB2. Does this perturbation cause a significant change in GNB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPS and then measure expression of GNB2. Does this perturbation cause a significant change in GNB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 47806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRNP40 is perturbed and the expression of PRKD2 is measured. Determine whether PRKD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRNP40 is perturbed and the expression of PRKD2 is measured. Determine whether PRKD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 87019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS51 is perturbed and SELENOM expression is measured. Determine whether SELENOM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS51 is perturbed and SELENOM expression is measured. Determine whether SELENOM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 108666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOP16 is perturbed and the expression of PTS is measured. Determine whether PTS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOP16 is perturbed and the expression of PTS is measured. Determine whether PTS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 72695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OPA1 is associated with a significant change in UBE3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OPA1 is associated with a significant change in UBE3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 62407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLE1, does the expression profile of DPP7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLE1, does the expression profile of DPP7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 105216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP6V1F is perturbed and the expression of MID1 is measured. Determine whether MID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP6V1F is perturbed and the expression of MID1 is measured. Determine whether MID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 47459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL2 is perturbed and RIT1 expression is measured. Determine whether RIT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL2 is perturbed and RIT1 expression is measured. Determine whether RIT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 44356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YPEL5 is perturbed and the expression of BTBD10 is measured. Determine whether BTBD10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YPEL5 is perturbed and the expression of BTBD10 is measured. Determine whether BTBD10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 16877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP160, does the expression profile of CLP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP160, does the expression profile of CLP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 119216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COQ4 is perturbed and the expression of SNHG5 is measured. Determine whether SNHG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COQ4 is perturbed and the expression of SNHG5 is measured. Determine whether SNHG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 14656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLD1 is perturbed and the expression of TUBB2A is measured. Determine whether TUBB2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLD1 is perturbed and the expression of TUBB2A is measured. Determine whether TUBB2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 68935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA2 is associated with a significant change in ECH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA2 is associated with a significant change in ECH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 7992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFAF3 is perturbed and BCL2L2 expression is quantified. Does this perturbation result in a significant change in BCL2L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFAF3 is perturbed and BCL2L2 expression is quantified. Does this perturbation result in a significant change in BCL2L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6438,"You are a functional genomics specialist. In K562 cells, we perturb DDX59 and monitor GADD45B expression. Decide whether this perturbation leads to a significant alteration in GADD45B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDX59 and monitor GADD45B expression. Decide whether this perturbation leads to a significant alteration in GADD45B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 29731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF207 and examine the expression of TSLP. Does perturbing ZNF207 lead to a significant change in TSLP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF207 and examine the expression of TSLP. Does perturbing ZNF207 lead to a significant change in TSLP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 63995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLASRP is associated with a significant change in PARP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLASRP is associated with a significant change in PARP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 122090,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPE is perturbed and the expression of TBC1D9B is measured. Does this perturbation cause a significant change in TBC1D9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPE is perturbed and the expression of TBC1D9B is measured. Does this perturbation cause a significant change in TBC1D9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 97014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOP1 and then measure expression of ERCC2. Does this perturbation cause a significant change in ERCC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOP1 and then measure expression of ERCC2. Does this perturbation cause a significant change in ERCC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 39394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USP7 and then measure expression of MRPL17. Does this perturbation cause a significant change in MRPL17 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USP7 and then measure expression of MRPL17. Does this perturbation cause a significant change in MRPL17 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 7253,You are an expert in regulatory genomics. Consider data from K562 cells in which RFC2 is perturbed and NBDY expression is observed. Does this perturbation lead to a significant difference in NBDY expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RFC2 is perturbed and NBDY expression is observed. Does this perturbation lead to a significant difference in NBDY expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 13452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS6 is perturbed and SSB expression is quantified. Does this perturbation result in a significant change in SSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS6 is perturbed and SSB expression is quantified. Does this perturbation result in a significant change in SSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 30141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT2 and examine the expression of LMBR1. Does perturbing ZNHIT2 lead to a significant change in LMBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT2 and examine the expression of LMBR1. Does perturbing ZNHIT2 lead to a significant change in LMBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 116110,"You are an expert in single-cell biology and functional genomics. In K562 cells, DYNC1I2 is perturbed and the expression of MBD5 is measured. Does this perturbation cause a significant change in MBD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DYNC1I2 is perturbed and the expression of MBD5 is measured. Does this perturbation cause a significant change in MBD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 25118,"You are a functional genomics specialist. In K562 cells, we perturb KRT8 and monitor EIF2D expression. Decide whether this perturbation leads to a significant alteration in EIF2D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KRT8 and monitor EIF2D expression. Decide whether this perturbation leads to a significant alteration in EIF2D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 66750,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL13 is perturbed and the expression of ZNF574 is measured. Does this perturbation cause a significant change in ZNF574 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL13 is perturbed and the expression of ZNF574 is measured. Does this perturbation cause a significant change in ZNF574 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 105108,"You are a functional genomics specialist. In K562 cells, we perturb HNRNPU and monitor CIAO1 expression. Decide whether this perturbation leads to a significant alteration in CIAO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HNRNPU and monitor CIAO1 expression. Decide whether this perturbation leads to a significant alteration in CIAO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 55065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF4A is associated with a significant change in OGFOD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF4A is associated with a significant change in OGFOD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 24609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPL is perturbed and SMARCAL1 expression is measured. Determine whether SMARCAL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPL is perturbed and SMARCAL1 expression is measured. Determine whether SMARCAL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 35708,"You are a functional genomics specialist. In K562 cells, we perturb HARS2 and monitor FAM234A expression. Decide whether this perturbation leads to a significant alteration in FAM234A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HARS2 and monitor FAM234A expression. Decide whether this perturbation leads to a significant alteration in FAM234A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 103916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUT is perturbed and the expression of RARB is measured. Determine whether RARB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUT is perturbed and the expression of RARB is measured. Determine whether RARB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 110025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUDT21 is associated with a significant change in TRAPPC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUDT21 is associated with a significant change in TRAPPC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 54846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RFC1 is perturbed and the expression of KDELR1 is measured. Determine whether KDELR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RFC1 is perturbed and the expression of KDELR1 is measured. Determine whether KDELR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 121745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3B2 is associated with a significant change in CEBPZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3B2 is associated with a significant change in CEBPZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 98072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRSF2 is perturbed and MOSPD3 expression is quantified. Does this perturbation result in a significant change in MOSPD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRSF2 is perturbed and MOSPD3 expression is quantified. Does this perturbation result in a significant change in MOSPD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 22741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SS18L2 and examine the expression of ABHD10. Does perturbing SS18L2 lead to a significant change in ABHD10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SS18L2 and examine the expression of ABHD10. Does perturbing SS18L2 lead to a significant change in ABHD10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 17192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC8 is perturbed and NDUFAF1 expression is quantified. Does this perturbation result in a significant change in NDUFAF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC8 is perturbed and NDUFAF1 expression is quantified. Does this perturbation result in a significant change in NDUFAF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 83859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYRM4 is perturbed and NCAPH2 expression is measured. Determine whether NCAPH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYRM4 is perturbed and NCAPH2 expression is measured. Determine whether NCAPH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 30129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DGCR8 is perturbed and TMEM250 expression is measured. Determine whether TMEM250 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DGCR8 is perturbed and TMEM250 expression is measured. Determine whether TMEM250 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 66299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR1B is perturbed and TMEM132A expression is measured. Determine whether TMEM132A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR1B is perturbed and TMEM132A expression is measured. Determine whether TMEM132A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 71230,"You are an expert in single-cell biology and functional genomics. In K562 cells, NLE1 is perturbed and the expression of CDC42EP3 is measured. Does this perturbation cause a significant change in CDC42EP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NLE1 is perturbed and the expression of CDC42EP3 is measured. Does this perturbation cause a significant change in CDC42EP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 67919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NACA is perturbed and EPB41L4A-AS1 expression is measured. Determine whether EPB41L4A-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NACA is perturbed and EPB41L4A-AS1 expression is measured. Determine whether EPB41L4A-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 78626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NFYB is perturbed and the expression of PTPN23 is measured. Determine whether PTPN23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NFYB is perturbed and the expression of PTPN23 is measured. Determine whether PTPN23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 11321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTK2 and examine the expression of USE1. Does perturbing PTK2 lead to a significant change in USE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTK2 and examine the expression of USE1. Does perturbing PTK2 lead to a significant change in USE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 14890,"You are an expert in single-cell biology and functional genomics. In K562 cells, TACC3 is perturbed and the expression of HSPA5 is measured. Does this perturbation cause a significant change in HSPA5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TACC3 is perturbed and the expression of HSPA5 is measured. Does this perturbation cause a significant change in HSPA5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 28625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL34 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL34 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 18806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP85 is perturbed and the expression of HIST3H2A is measured. Determine whether HIST3H2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP85 is perturbed and the expression of HIST3H2A is measured. Determine whether HIST3H2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 64445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF3C6 is associated with a significant change in IFRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF3C6 is associated with a significant change in IFRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 34260,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNOT3 is perturbed and the expression of COPS7A is measured. Does this perturbation cause a significant change in COPS7A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNOT3 is perturbed and the expression of COPS7A is measured. Does this perturbation cause a significant change in COPS7A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 84526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COA5 is perturbed and the expression of BLOC1S5 is measured. Determine whether BLOC1S5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COA5 is perturbed and the expression of BLOC1S5 is measured. Determine whether BLOC1S5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 117876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABCB7 is perturbed and the expression of TGFB2 is measured. Determine whether TGFB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABCB7 is perturbed and the expression of TGFB2 is measured. Determine whether TGFB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 51052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3A is perturbed and IL1B expression is quantified. Does this perturbation result in a significant change in IL1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3A is perturbed and IL1B expression is quantified. Does this perturbation result in a significant change in IL1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 29006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TPT1 is perturbed and the expression of SCD is measured. Determine whether SCD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TPT1 is perturbed and the expression of SCD is measured. Determine whether SCD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 83923,You are an expert in regulatory genomics. Consider data from K562 cells in which TCOF1 is perturbed and IL1B expression is observed. Does this perturbation lead to a significant difference in IL1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TCOF1 is perturbed and IL1B expression is observed. Does this perturbation lead to a significant difference in IL1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 119703,You are an expert in regulatory genomics. Consider data from K562 cells in which COPS4 is perturbed and RECK expression is observed. Does this perturbation lead to a significant difference in RECK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPS4 is perturbed and RECK expression is observed. Does this perturbation lead to a significant difference in RECK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 88184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AAAS and then measure expression of TMEM134. Does this perturbation cause a significant change in TMEM134 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AAAS and then measure expression of TMEM134. Does this perturbation cause a significant change in TMEM134 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 22932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NR2C2AP is perturbed and ADAM19 expression is quantified. Does this perturbation result in a significant change in ADAM19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NR2C2AP is perturbed and ADAM19 expression is quantified. Does this perturbation result in a significant change in ADAM19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 118539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCEE is perturbed and BBIP1 expression is measured. Determine whether BBIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCEE is perturbed and BBIP1 expression is measured. Determine whether BBIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 42803,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL10 is perturbed and CSNK2A2 expression is observed. Does this perturbation lead to a significant difference in CSNK2A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL10 is perturbed and CSNK2A2 expression is observed. Does this perturbation lead to a significant difference in CSNK2A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 77778,"You are a functional genomics specialist. In K562 cells, we perturb DICER1 and monitor ADAM12 expression. Decide whether this perturbation leads to a significant alteration in ADAM12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DICER1 and monitor ADAM12 expression. Decide whether this perturbation leads to a significant alteration in ADAM12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 36665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DPY19L4 is associated with a significant change in GPATCH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DPY19L4 is associated with a significant change in GPATCH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 75495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VBP1 is associated with a significant change in C11orf49 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VBP1 is associated with a significant change in C11orf49 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 112730,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1E1 is perturbed and the expression of TM7SF2 is measured. Does this perturbation cause a significant change in TM7SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1E1 is perturbed and the expression of TM7SF2 is measured. Does this perturbation cause a significant change in TM7SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1278,"You are a functional genomics specialist. In K562 cells, we perturb TFAM and monitor RBM18 expression. Decide whether this perturbation leads to a significant alteration in RBM18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TFAM and monitor RBM18 expression. Decide whether this perturbation leads to a significant alteration in RBM18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 86246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCF11 is perturbed and the expression of FGD4 is measured. Determine whether FGD4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCF11 is perturbed and the expression of FGD4 is measured. Determine whether FGD4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 93475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STARD7 is associated with a significant change in HCFC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STARD7 is associated with a significant change in HCFC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 97115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CINP is associated with a significant change in NRBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CINP is associated with a significant change in NRBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 58218,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC9 and monitor VPS39 expression. Decide whether this perturbation leads to a significant alteration in VPS39 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC9 and monitor VPS39 expression. Decide whether this perturbation leads to a significant alteration in VPS39 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 96681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DSN1 and examine the expression of TRAFD1. Does perturbing DSN1 lead to a significant change in TRAFD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DSN1 and examine the expression of TRAFD1. Does perturbing DSN1 lead to a significant change in TRAFD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 34264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNOT3 and then measure expression of COPS7A. Does this perturbation cause a significant change in COPS7A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNOT3 and then measure expression of COPS7A. Does this perturbation cause a significant change in COPS7A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of EPHX1. Does perturbing HSPA9 lead to a significant change in EPHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of EPHX1. Does perturbing HSPA9 lead to a significant change in EPHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 100288,"You are a functional genomics specialist. In K562 cells, we perturb PET117 and monitor COPE expression. Decide whether this perturbation leads to a significant alteration in COPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PET117 and monitor COPE expression. Decide whether this perturbation leads to a significant alteration in COPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 39945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRMT5 is associated with a significant change in RAB30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRMT5 is associated with a significant change in RAB30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 9869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM199 is perturbed and MICU1 expression is measured. Determine whether MICU1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM199 is perturbed and MICU1 expression is measured. Determine whether MICU1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 118916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of CHCHD3 is measured. Determine whether CHCHD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of CHCHD3 is measured. Determine whether CHCHD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 36248,"You are a functional genomics specialist. In K562 cells, we perturb RCOR1 and monitor ARRB2 expression. Decide whether this perturbation leads to a significant alteration in ARRB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RCOR1 and monitor ARRB2 expression. Decide whether this perturbation leads to a significant alteration in ARRB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 93873,You are an expert in regulatory genomics. Consider data from K562 cells in which NAF1 is perturbed and ANXA3 expression is observed. Does this perturbation lead to a significant difference in ANXA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NAF1 is perturbed and ANXA3 expression is observed. Does this perturbation lead to a significant difference in ANXA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 19222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPA1 is perturbed and CYB5R1 expression is quantified. Does this perturbation result in a significant change in CYB5R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPA1 is perturbed and CYB5R1 expression is quantified. Does this perturbation result in a significant change in CYB5R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 9728,"You are a functional genomics specialist. In K562 cells, we perturb CIAO1 and monitor SHARPIN expression. Decide whether this perturbation leads to a significant alteration in SHARPIN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CIAO1 and monitor SHARPIN expression. Decide whether this perturbation leads to a significant alteration in SHARPIN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 77912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS11 is perturbed and RNF20 expression is quantified. Does this perturbation result in a significant change in RNF20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS11 is perturbed and RNF20 expression is quantified. Does this perturbation result in a significant change in RNF20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 103353,You are an expert in regulatory genomics. Consider data from K562 cells in which SHOC2 is perturbed and RPS8 expression is observed. Does this perturbation lead to a significant difference in RPS8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SHOC2 is perturbed and RPS8 expression is observed. Does this perturbation lead to a significant difference in RPS8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 9232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCP110 is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCP110 is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 65615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERAL1 is associated with a significant change in SSH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERAL1 is associated with a significant change in SSH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 68176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF8 is perturbed and the expression of SDHD is measured. Determine whether SDHD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF8 is perturbed and the expression of SDHD is measured. Determine whether SDHD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 115405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMA2 is associated with a significant change in PCNX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMA2 is associated with a significant change in PCNX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 42152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSG101 is perturbed and CRIP2 expression is quantified. Does this perturbation result in a significant change in CRIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSG101 is perturbed and CRIP2 expression is quantified. Does this perturbation result in a significant change in CRIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 57603,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35G2 is perturbed and LARS2 expression is observed. Does this perturbation lead to a significant difference in LARS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35G2 is perturbed and LARS2 expression is observed. Does this perturbation lead to a significant difference in LARS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 51035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3A is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3A is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 108983,You are an expert in regulatory genomics. Consider data from K562 cells in which UTP3 is perturbed and EIF4B expression is observed. Does this perturbation lead to a significant difference in EIF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UTP3 is perturbed and EIF4B expression is observed. Does this perturbation lead to a significant difference in EIF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 52531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSFM and examine the expression of DHODH. Does perturbing TSFM lead to a significant change in DHODH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSFM and examine the expression of DHODH. Does perturbing TSFM lead to a significant change in DHODH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 21306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBM12 is perturbed and the expression of SMPD1 is measured. Determine whether SMPD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBM12 is perturbed and the expression of SMPD1 is measured. Determine whether SMPD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRNT1, does the expression profile of CTTNBP2NL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRNT1, does the expression profile of CTTNBP2NL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 107694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of SERPINE2. Does this perturbation cause a significant change in SERPINE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of SERPINE2. Does this perturbation cause a significant change in SERPINE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 33513,You are an expert in regulatory genomics. Consider data from K562 cells in which TADA2B is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TADA2B is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 104319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RAD17 is perturbed and TMEM161B-AS1 expression is measured. Determine whether TMEM161B-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RAD17 is perturbed and TMEM161B-AS1 expression is measured. Determine whether TMEM161B-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 61178,"You are a functional genomics specialist. In K562 cells, we perturb RABGGTA and monitor ZNF574 expression. Decide whether this perturbation leads to a significant alteration in ZNF574 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RABGGTA and monitor ZNF574 expression. Decide whether this perturbation leads to a significant alteration in ZNF574 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 72893,You are an expert in regulatory genomics. Consider data from K562 cells in which MAGOH is perturbed and CLSTN2 expression is observed. Does this perturbation lead to a significant difference in CLSTN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAGOH is perturbed and CLSTN2 expression is observed. Does this perturbation lead to a significant difference in CLSTN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 40235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MSRB1 is associated with a significant change in TMED5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MSRB1 is associated with a significant change in TMED5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 116852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPIE is perturbed and TMEM14A expression is quantified. Does this perturbation result in a significant change in TMEM14A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPIE is perturbed and TMEM14A expression is quantified. Does this perturbation result in a significant change in TMEM14A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 60896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EMC4 is perturbed and the expression of ME1 is measured. Determine whether ME1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EMC4 is perturbed and the expression of ME1 is measured. Determine whether ME1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 31911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H18 and examine the expression of MTRNR2L12. Does perturbing ZC3H18 lead to a significant change in MTRNR2L12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H18 and examine the expression of MTRNR2L12. Does perturbing ZC3H18 lead to a significant change in MTRNR2L12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOL9 and examine the expression of PUS1. Does perturbing NOL9 lead to a significant change in PUS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOL9 and examine the expression of PUS1. Does perturbing NOL9 lead to a significant change in PUS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 18989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSEN34 is perturbed and C15orf61 expression is measured. Determine whether C15orf61 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSEN34 is perturbed and C15orf61 expression is measured. Determine whether C15orf61 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 34758,"You are a functional genomics specialist. In K562 cells, we perturb SRP19 and monitor OS9 expression. Decide whether this perturbation leads to a significant alteration in OS9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP19 and monitor OS9 expression. Decide whether this perturbation leads to a significant alteration in OS9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 14913,You are an expert in regulatory genomics. Consider data from K562 cells in which TOMM20 is perturbed and ABI1 expression is observed. Does this perturbation lead to a significant difference in ABI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TOMM20 is perturbed and ABI1 expression is observed. Does this perturbation lead to a significant difference in ABI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 54069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UTP25 is perturbed and BBS2 expression is measured. Determine whether BBS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UTP25 is perturbed and BBS2 expression is measured. Determine whether BBS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 98967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCT2, does the expression profile of ZNF217 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCT2, does the expression profile of ZNF217 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 122942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METAP2 is perturbed and REST expression is quantified. Does this perturbation result in a significant change in REST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METAP2 is perturbed and REST expression is quantified. Does this perturbation result in a significant change in REST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 17774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CPNE7 and then measure expression of MCC. Does this perturbation cause a significant change in MCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CPNE7 and then measure expression of MCC. Does this perturbation cause a significant change in MCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 28263,You are an expert in regulatory genomics. Consider data from K562 cells in which SDHAF2 is perturbed and CDC5L expression is observed. Does this perturbation lead to a significant difference in CDC5L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SDHAF2 is perturbed and CDC5L expression is observed. Does this perturbation lead to a significant difference in CDC5L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 72965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNF8 is associated with a significant change in CXCL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNF8 is associated with a significant change in CXCL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 63299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCM2 is perturbed and GPRC5A expression is measured. Determine whether GPRC5A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCM2 is perturbed and GPRC5A expression is measured. Determine whether GPRC5A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 95458,"You are a functional genomics specialist. In K562 cells, we perturb FGFR1OP and monitor RND3 expression. Decide whether this perturbation leads to a significant alteration in RND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FGFR1OP and monitor RND3 expression. Decide whether this perturbation leads to a significant alteration in RND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 74768,"You are a functional genomics specialist. In K562 cells, we perturb IMPA2 and monitor MOSPD1 expression. Decide whether this perturbation leads to a significant alteration in MOSPD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IMPA2 and monitor MOSPD1 expression. Decide whether this perturbation leads to a significant alteration in MOSPD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 52005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B5 is associated with a significant change in SNX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B5 is associated with a significant change in SNX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 37801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RSF1. Does perturbing EIF2S1 lead to a significant change in RSF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RSF1. Does perturbing EIF2S1 lead to a significant change in RSF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 42110,"You are an expert in single-cell biology and functional genomics. In K562 cells, BUB3 is perturbed and the expression of DNAJB4 is measured. Does this perturbation cause a significant change in DNAJB4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BUB3 is perturbed and the expression of DNAJB4 is measured. Does this perturbation cause a significant change in DNAJB4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 65826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLNS1A is perturbed and the expression of RIN2 is measured. Determine whether RIN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLNS1A is perturbed and the expression of RIN2 is measured. Determine whether RIN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 95888,"You are a functional genomics specialist. In K562 cells, we perturb MAX and monitor SNAPC1 expression. Decide whether this perturbation leads to a significant alteration in SNAPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAX and monitor SNAPC1 expression. Decide whether this perturbation leads to a significant alteration in SNAPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 109370,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R11 is perturbed and the expression of KAT6B is measured. Does this perturbation cause a significant change in KAT6B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R11 is perturbed and the expression of KAT6B is measured. Does this perturbation cause a significant change in KAT6B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 123225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CTCF is associated with a significant change in SLC35A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CTCF is associated with a significant change in SLC35A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 49007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PI4KA, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PI4KA, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 41957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX3X, does the expression profile of SNX21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX3X, does the expression profile of SNX21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 26291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPK and examine the expression of STK4. Does perturbing CENPK lead to a significant change in STK4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPK and examine the expression of STK4. Does perturbing CENPK lead to a significant change in STK4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 47169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEP97 is perturbed and ZMYM2 expression is measured. Determine whether ZMYM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEP97 is perturbed and ZMYM2 expression is measured. Determine whether ZMYM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 26587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NARS2, does the expression profile of ANKZF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NARS2, does the expression profile of ANKZF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 72010,"You are an expert in single-cell biology and functional genomics. In K562 cells, PMPCA is perturbed and the expression of GADD45A is measured. Does this perturbation cause a significant change in GADD45A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PMPCA is perturbed and the expression of GADD45A is measured. Does this perturbation cause a significant change in GADD45A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 93453,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS28 is perturbed and SEM1 expression is observed. Does this perturbation lead to a significant difference in SEM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS28 is perturbed and SEM1 expression is observed. Does this perturbation lead to a significant difference in SEM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 17175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS17 is associated with a significant change in MSH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS17 is associated with a significant change in MSH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 78081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CWC15 and examine the expression of AOPEP. Does perturbing CWC15 lead to a significant change in AOPEP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CWC15 and examine the expression of AOPEP. Does perturbing CWC15 lead to a significant change in AOPEP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 18819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NUP85 is perturbed and XPC expression is measured. Determine whether XPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NUP85 is perturbed and XPC expression is measured. Determine whether XPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 119780,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMB7 is perturbed and the expression of TNNT1 is measured. Does this perturbation cause a significant change in TNNT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMB7 is perturbed and the expression of TNNT1 is measured. Does this perturbation cause a significant change in TNNT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 82823,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and RCOR1 expression is observed. Does this perturbation lead to a significant difference in RCOR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and RCOR1 expression is observed. Does this perturbation lead to a significant difference in RCOR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 42020,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAPC5 is perturbed and the expression of SSR4 is measured. Does this perturbation cause a significant change in SSR4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAPC5 is perturbed and the expression of SSR4 is measured. Does this perturbation cause a significant change in SSR4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 94861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD11 and examine the expression of NXPE3. Does perturbing PSMD11 lead to a significant change in NXPE3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD11 and examine the expression of NXPE3. Does perturbing PSMD11 lead to a significant change in NXPE3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 106428,"You are a functional genomics specialist. In K562 cells, we perturb ARRB2 and monitor ZNF609 expression. Decide whether this perturbation leads to a significant alteration in ZNF609 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARRB2 and monitor ZNF609 expression. Decide whether this perturbation leads to a significant alteration in ZNF609 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 28180,"You are an expert in single-cell biology and functional genomics. In K562 cells, RAN is perturbed and the expression of CPSF4 is measured. Does this perturbation cause a significant change in CPSF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RAN is perturbed and the expression of CPSF4 is measured. Does this perturbation cause a significant change in CPSF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 97569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALG14 is perturbed and KAT6B expression is measured. Determine whether KAT6B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALG14 is perturbed and KAT6B expression is measured. Determine whether KAT6B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 87984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AFG3L2 and then measure expression of TMEM179B. Does this perturbation cause a significant change in TMEM179B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AFG3L2 and then measure expression of TMEM179B. Does this perturbation cause a significant change in TMEM179B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 78716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD6 is perturbed and the expression of BRD1 is measured. Determine whether BRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD6 is perturbed and the expression of BRD1 is measured. Determine whether BRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 90492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and EMC3 expression is quantified. Does this perturbation result in a significant change in EMC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and EMC3 expression is quantified. Does this perturbation result in a significant change in EMC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 7475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L1 is associated with a significant change in CEP83 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L1 is associated with a significant change in CEP83 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4283,You are an expert in regulatory genomics. Consider data from K562 cells in which UBR4 is perturbed and SUGP2 expression is observed. Does this perturbation lead to a significant difference in SUGP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBR4 is perturbed and SUGP2 expression is observed. Does this perturbation lead to a significant difference in SUGP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 46106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB4A is perturbed and the expression of CCDC174 is measured. Determine whether CCDC174 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB4A is perturbed and the expression of CCDC174 is measured. Determine whether CCDC174 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 110176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRIAP1 is perturbed and the expression of AKIRIN1 is measured. Determine whether AKIRIN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRIAP1 is perturbed and the expression of AKIRIN1 is measured. Determine whether AKIRIN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 53435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4G2 is associated with a significant change in RAP2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4G2 is associated with a significant change in RAP2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 87499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL50 is perturbed and BHLHE40 expression is measured. Determine whether BHLHE40 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL50 is perturbed and BHLHE40 expression is measured. Determine whether BHLHE40 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 69442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNM2 is perturbed and CZIB expression is quantified. Does this perturbation result in a significant change in CZIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNM2 is perturbed and CZIB expression is quantified. Does this perturbation result in a significant change in CZIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 45578,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor SYF2 expression. Decide whether this perturbation leads to a significant alteration in SYF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor SYF2 expression. Decide whether this perturbation leads to a significant alteration in SYF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 93990,"You are an expert in single-cell biology and functional genomics. In K562 cells, KANSL3 is perturbed and the expression of GIT1 is measured. Does this perturbation cause a significant change in GIT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KANSL3 is perturbed and the expression of GIT1 is measured. Does this perturbation cause a significant change in GIT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 30621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2H and examine the expression of AKT2. Does perturbing UBE2H lead to a significant change in AKT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2H and examine the expression of AKT2. Does perturbing UBE2H lead to a significant change in AKT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 88236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ESYT1 is perturbed and the expression of INSIG2 is measured. Determine whether INSIG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ESYT1 is perturbed and the expression of INSIG2 is measured. Determine whether INSIG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 70346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AASDHPPT is perturbed and the expression of TONSL is measured. Determine whether TONSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AASDHPPT is perturbed and the expression of TONSL is measured. Determine whether TONSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 43356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOP2 is perturbed and the expression of HCG18 is measured. Determine whether HCG18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOP2 is perturbed and the expression of HCG18 is measured. Determine whether HCG18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 27684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPS6 and then measure expression of COX10. Does this perturbation cause a significant change in COX10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPS6 and then measure expression of COX10. Does this perturbation cause a significant change in COX10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 22293,You are an expert in regulatory genomics. Consider data from K562 cells in which SIRT7 is perturbed and DNAJB4 expression is observed. Does this perturbation lead to a significant difference in DNAJB4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SIRT7 is perturbed and DNAJB4 expression is observed. Does this perturbation lead to a significant difference in DNAJB4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 13259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UPF3A is perturbed and TMEM126B expression is measured. Determine whether TMEM126B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UPF3A is perturbed and TMEM126B expression is measured. Determine whether TMEM126B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 105467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TINF2, does the expression profile of LMLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TINF2, does the expression profile of LMLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 91484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3H and then measure expression of RPSA. Does this perturbation cause a significant change in RPSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3H and then measure expression of RPSA. Does this perturbation cause a significant change in RPSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 68886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEH1L is perturbed and the expression of VGLL3 is measured. Determine whether VGLL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEH1L is perturbed and the expression of VGLL3 is measured. Determine whether VGLL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 55437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR3B, does the expression profile of TRIB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR3B, does the expression profile of TRIB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 101610,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1 is perturbed and the expression of SNAPC1 is measured. Does this perturbation cause a significant change in SNAPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1 is perturbed and the expression of SNAPC1 is measured. Does this perturbation cause a significant change in SNAPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 32648,"You are a functional genomics specialist. In K562 cells, we perturb YTHDC1 and monitor C1orf56 expression. Decide whether this perturbation leads to a significant alteration in C1orf56 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb YTHDC1 and monitor C1orf56 expression. Decide whether this perturbation leads to a significant alteration in C1orf56 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 29060,"You are an expert in single-cell biology and functional genomics. In K562 cells, SON is perturbed and the expression of MOB2 is measured. Does this perturbation cause a significant change in MOB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SON is perturbed and the expression of MOB2 is measured. Does this perturbation cause a significant change in MOB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 103687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOC3L, does the expression profile of DPCD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOC3L, does the expression profile of DPCD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 36362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SP1 is perturbed and PTPRK expression is quantified. Does this perturbation result in a significant change in PTPRK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SP1 is perturbed and PTPRK expression is quantified. Does this perturbation result in a significant change in PTPRK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 83548,"You are a functional genomics specialist. In K562 cells, we perturb MBIP and monitor LAYN expression. Decide whether this perturbation leads to a significant alteration in LAYN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MBIP and monitor LAYN expression. Decide whether this perturbation leads to a significant alteration in LAYN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 85553,You are an expert in regulatory genomics. Consider data from K562 cells in which RMI1 is perturbed and DNASE1L1 expression is observed. Does this perturbation lead to a significant difference in DNASE1L1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RMI1 is perturbed and DNASE1L1 expression is observed. Does this perturbation lead to a significant difference in DNASE1L1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 33710,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDCD2 is perturbed and the expression of LIMA1 is measured. Does this perturbation cause a significant change in LIMA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDCD2 is perturbed and the expression of LIMA1 is measured. Does this perturbation cause a significant change in LIMA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 105336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBCB is perturbed and the expression of MRS2 is measured. Determine whether MRS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBCB is perturbed and the expression of MRS2 is measured. Determine whether MRS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 34580,"You are an expert in single-cell biology and functional genomics. In K562 cells, INTS14 is perturbed and the expression of KRT80 is measured. Does this perturbation cause a significant change in KRT80 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, INTS14 is perturbed and the expression of KRT80 is measured. Does this perturbation cause a significant change in KRT80 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 7109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSR1 is perturbed and PBX1 expression is measured. Determine whether PBX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSR1 is perturbed and PBX1 expression is measured. Determine whether PBX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 8483,You are an expert in regulatory genomics. Consider data from K562 cells in which MED24 is perturbed and ZNF106 expression is observed. Does this perturbation lead to a significant difference in ZNF106 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MED24 is perturbed and ZNF106 expression is observed. Does this perturbation lead to a significant difference in ZNF106 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 66002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISCU is perturbed and KRCC1 expression is quantified. Does this perturbation result in a significant change in KRCC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISCU is perturbed and KRCC1 expression is quantified. Does this perturbation result in a significant change in KRCC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 119741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPS4 and examine the expression of RNF169. Does perturbing COPS4 lead to a significant change in RNF169 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPS4 and examine the expression of RNF169. Does perturbing COPS4 lead to a significant change in RNF169 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 67404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS29 and then measure expression of SLC35B3. Does this perturbation cause a significant change in SLC35B3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS29 and then measure expression of SLC35B3. Does this perturbation cause a significant change in SLC35B3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 105394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USF2 and then measure expression of NPEPPS. Does this perturbation cause a significant change in NPEPPS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USF2 and then measure expression of NPEPPS. Does this perturbation cause a significant change in NPEPPS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 109917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRRAP, does the expression profile of LTBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRRAP, does the expression profile of LTBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 24476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYF2 is perturbed and the expression of APAF1 is measured. Determine whether APAF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYF2 is perturbed and the expression of APAF1 is measured. Determine whether APAF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 114257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR1A, does the expression profile of IFT80 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR1A, does the expression profile of IFT80 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 9703,You are an expert in regulatory genomics. Consider data from K562 cells in which CIAO1 is perturbed and SDHA expression is observed. Does this perturbation lead to a significant difference in SDHA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CIAO1 is perturbed and SDHA expression is observed. Does this perturbation lead to a significant difference in SDHA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUVBL2 is associated with a significant change in GFM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUVBL2 is associated with a significant change in GFM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 117614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC45 and then measure expression of CHIC2. Does this perturbation cause a significant change in CHIC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC45 and then measure expression of CHIC2. Does this perturbation cause a significant change in CHIC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 32918,"You are a functional genomics specialist. In K562 cells, we perturb NCKAP1 and monitor B4GAT1 expression. Decide whether this perturbation leads to a significant alteration in B4GAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NCKAP1 and monitor B4GAT1 expression. Decide whether this perturbation leads to a significant alteration in B4GAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2000,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R2 is perturbed and the expression of VRK3 is measured. Does this perturbation cause a significant change in VRK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R2 is perturbed and the expression of VRK3 is measured. Does this perturbation cause a significant change in VRK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 30747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LSM4, does the expression profile of VGLL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LSM4, does the expression profile of VGLL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 54588,"You are a functional genomics specialist. In K562 cells, we perturb POLR3H and monitor NREP expression. Decide whether this perturbation leads to a significant alteration in NREP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb POLR3H and monitor NREP expression. Decide whether this perturbation leads to a significant alteration in NREP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 43526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JAZF1 is perturbed and the expression of TMEM184B is measured. Determine whether TMEM184B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JAZF1 is perturbed and the expression of TMEM184B is measured. Determine whether TMEM184B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FAM136A is perturbed and the expression of FAM171B is measured. Determine whether FAM171B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FAM136A is perturbed and the expression of FAM171B is measured. Determine whether FAM171B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 97469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NF1 is perturbed and NUP188 expression is measured. Determine whether NUP188 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NF1 is perturbed and NUP188 expression is measured. Determine whether NUP188 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 36488,"You are a functional genomics specialist. In K562 cells, we perturb NDUFA3 and monitor CTSB expression. Decide whether this perturbation leads to a significant alteration in CTSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NDUFA3 and monitor CTSB expression. Decide whether this perturbation leads to a significant alteration in CTSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 32028,"You are a functional genomics specialist. In K562 cells, we perturb SMG1 and monitor ANAPC16 expression. Decide whether this perturbation leads to a significant alteration in ANAPC16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SMG1 and monitor ANAPC16 expression. Decide whether this perturbation leads to a significant alteration in ANAPC16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 121081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED10 and examine the expression of COL4A1. Does perturbing MED10 lead to a significant change in COL4A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED10 and examine the expression of COL4A1. Does perturbing MED10 lead to a significant change in COL4A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 340,"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD5 is perturbed and the expression of SLC6A15 is measured. Does this perturbation cause a significant change in SLC6A15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD5 is perturbed and the expression of SLC6A15 is measured. Does this perturbation cause a significant change in SLC6A15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 90707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VCP, does the expression profile of HSF2BP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VCP, does the expression profile of HSF2BP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 100635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNMT1 is associated with a significant change in THSD4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNMT1 is associated with a significant change in THSD4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 95865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOSC1 is associated with a significant change in LINC02762 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOSC1 is associated with a significant change in LINC02762 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 15101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2E2 and examine the expression of FBXO11. Does perturbing GTF2E2 lead to a significant change in FBXO11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2E2 and examine the expression of FBXO11. Does perturbing GTF2E2 lead to a significant change in FBXO11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 71406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHX36 is perturbed and the expression of CCDC82 is measured. Determine whether CCDC82 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHX36 is perturbed and the expression of CCDC82 is measured. Determine whether CCDC82 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 93151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIP7 and examine the expression of RPL41. Does perturbing NIP7 lead to a significant change in RPL41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIP7 and examine the expression of RPL41. Does perturbing NIP7 lead to a significant change in RPL41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 101819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHMP7 is perturbed and ORAI3 expression is measured. Determine whether ORAI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHMP7 is perturbed and ORAI3 expression is measured. Determine whether ORAI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 41604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL38 and then measure expression of GTF2F1. Does this perturbation cause a significant change in GTF2F1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL38 and then measure expression of GTF2F1. Does this perturbation cause a significant change in GTF2F1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 39995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3M is associated with a significant change in PCIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3M is associated with a significant change in PCIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 69987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBBP8, does the expression profile of RPS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBBP8, does the expression profile of RPS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 49492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ECT2 is perturbed and MFSD3 expression is quantified. Does this perturbation result in a significant change in MFSD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ECT2 is perturbed and MFSD3 expression is quantified. Does this perturbation result in a significant change in MFSD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 42318,"You are a functional genomics specialist. In K562 cells, we perturb ZNF143 and monitor GIHCG expression. Decide whether this perturbation leads to a significant alteration in GIHCG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZNF143 and monitor GIHCG expression. Decide whether this perturbation leads to a significant alteration in GIHCG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 32294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ADSL and then measure expression of CHST12. Does this perturbation cause a significant change in CHST12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ADSL and then measure expression of CHST12. Does this perturbation cause a significant change in CHST12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 39872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBA3 is perturbed and STX1A expression is quantified. Does this perturbation result in a significant change in STX1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBA3 is perturbed and STX1A expression is quantified. Does this perturbation result in a significant change in STX1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 29381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC4 and examine the expression of CD44. Does perturbing ANAPC4 lead to a significant change in CD44 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC4 and examine the expression of CD44. Does perturbing ANAPC4 lead to a significant change in CD44 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 66283,You are an expert in regulatory genomics. Consider data from K562 cells in which SKA1 is perturbed and DHX40 expression is observed. Does this perturbation lead to a significant difference in DHX40 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SKA1 is perturbed and DHX40 expression is observed. Does this perturbation lead to a significant difference in DHX40 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 96809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HCFC1 is perturbed and STXBP1 expression is measured. Determine whether STXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HCFC1 is perturbed and STXBP1 expression is measured. Determine whether STXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 27695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPS6 is associated with a significant change in TNPO2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPS6 is associated with a significant change in TNPO2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 94592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and GCDH expression is quantified. Does this perturbation result in a significant change in GCDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and GCDH expression is quantified. Does this perturbation result in a significant change in GCDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 76578,"You are a functional genomics specialist. In K562 cells, we perturb ARGLU1 and monitor ING5 expression. Decide whether this perturbation leads to a significant alteration in ING5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARGLU1 and monitor ING5 expression. Decide whether this perturbation leads to a significant alteration in ING5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 32325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ADSL is associated with a significant change in ECHS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ADSL is associated with a significant change in ECHS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 12217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3J, does the expression profile of PNRC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3J, does the expression profile of PNRC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 66986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTR2 is perturbed and the expression of USP45 is measured. Determine whether USP45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTR2 is perturbed and the expression of USP45 is measured. Determine whether USP45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 109695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in EXOSC7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in EXOSC7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 20561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PHAX and examine the expression of UBE2E1. Does perturbing PHAX lead to a significant change in UBE2E1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PHAX and examine the expression of UBE2E1. Does perturbing PHAX lead to a significant change in UBE2E1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 99969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC1 is perturbed and NID2 expression is measured. Determine whether NID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC1 is perturbed and NID2 expression is measured. Determine whether NID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 17125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS17 is associated with a significant change in ZMYM5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS17 is associated with a significant change in ZMYM5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 75415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNOT11 is associated with a significant change in WDR74 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNOT11 is associated with a significant change in WDR74 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 74132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPTF is perturbed and COQ4 expression is quantified. Does this perturbation result in a significant change in COQ4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPTF is perturbed and COQ4 expression is quantified. Does this perturbation result in a significant change in COQ4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 8135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3A2 is associated with a significant change in MAGI1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3A2 is associated with a significant change in MAGI1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 113860,"You are an expert in single-cell biology and functional genomics. In K562 cells, KXD1 is perturbed and the expression of SLC35E3 is measured. Does this perturbation cause a significant change in SLC35E3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KXD1 is perturbed and the expression of SLC35E3 is measured. Does this perturbation cause a significant change in SLC35E3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 95981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAPA and examine the expression of GPKOW. Does perturbing NAPA lead to a significant change in GPKOW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAPA and examine the expression of GPKOW. Does perturbing NAPA lead to a significant change in GPKOW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 68204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRPF8 and then measure expression of NEK7. Does this perturbation cause a significant change in NEK7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRPF8 and then measure expression of NEK7. Does this perturbation cause a significant change in NEK7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 66725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL13 is associated with a significant change in MMP24OS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL13 is associated with a significant change in MMP24OS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 19608,"You are a functional genomics specialist. In K562 cells, we perturb CCNK and monitor SAYSD1 expression. Decide whether this perturbation leads to a significant alteration in SAYSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCNK and monitor SAYSD1 expression. Decide whether this perturbation leads to a significant alteration in SAYSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 74561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRCC2 and examine the expression of IRAK4. Does perturbing XRCC2 lead to a significant change in IRAK4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRCC2 and examine the expression of IRAK4. Does perturbing XRCC2 lead to a significant change in IRAK4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 116734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DMAP1 and then measure expression of TCP11L1. Does this perturbation cause a significant change in TCP11L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DMAP1 and then measure expression of TCP11L1. Does this perturbation cause a significant change in TCP11L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 76074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHQ1 and then measure expression of COL4A5. Does this perturbation cause a significant change in COL4A5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHQ1 and then measure expression of COL4A5. Does this perturbation cause a significant change in COL4A5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 64380,"You are an expert in single-cell biology and functional genomics. In K562 cells, LARS2 is perturbed and the expression of MFAP2 is measured. Does this perturbation cause a significant change in MFAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LARS2 is perturbed and the expression of MFAP2 is measured. Does this perturbation cause a significant change in MFAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 38491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GSK3B and examine the expression of MAGI3. Does perturbing GSK3B lead to a significant change in MAGI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GSK3B and examine the expression of MAGI3. Does perturbing GSK3B lead to a significant change in MAGI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 37289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PARN is perturbed and MDM2 expression is measured. Determine whether MDM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PARN is perturbed and MDM2 expression is measured. Determine whether MDM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 75472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VBP1 is perturbed and C5orf46 expression is quantified. Does this perturbation result in a significant change in C5orf46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VBP1 is perturbed and C5orf46 expression is quantified. Does this perturbation result in a significant change in C5orf46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 114534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPT16H and then measure expression of TMEM161B-AS1. Does this perturbation cause a significant change in TMEM161B-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPT16H and then measure expression of TMEM161B-AS1. Does this perturbation cause a significant change in TMEM161B-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 91126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRAPPC5 is perturbed and the expression of COQ5 is measured. Determine whether COQ5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRAPPC5 is perturbed and the expression of COQ5 is measured. Determine whether COQ5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 55537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPP21, does the expression profile of NIBAN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPP21, does the expression profile of NIBAN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 67502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCS1L is perturbed and RYBP expression is quantified. Does this perturbation result in a significant change in RYBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCS1L is perturbed and RYBP expression is quantified. Does this perturbation result in a significant change in RYBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 12350,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPLP0 is perturbed and the expression of NR3C1 is measured. Does this perturbation cause a significant change in NR3C1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPLP0 is perturbed and the expression of NR3C1 is measured. Does this perturbation cause a significant change in NR3C1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 61868,"You are a functional genomics specialist. In K562 cells, we perturb DBF4 and monitor GPC1 expression. Decide whether this perturbation leads to a significant alteration in GPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DBF4 and monitor GPC1 expression. Decide whether this perturbation leads to a significant alteration in GPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 42380,"You are an expert in single-cell biology and functional genomics. In K562 cells, TRMT10C is perturbed and the expression of RBM28 is measured. Does this perturbation cause a significant change in RBM28 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TRMT10C is perturbed and the expression of RBM28 is measured. Does this perturbation cause a significant change in RBM28 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 58646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL6 is perturbed and the expression of BRPF1 is measured. Determine whether BRPF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL6 is perturbed and the expression of BRPF1 is measured. Determine whether BRPF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 122354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD2 and then measure expression of TFDP2. Does this perturbation cause a significant change in TFDP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD2 and then measure expression of TFDP2. Does this perturbation cause a significant change in TFDP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 121900,"You are an expert in single-cell biology and functional genomics. In K562 cells, THUMPD1 is perturbed and the expression of SMIM10L1 is measured. Does this perturbation cause a significant change in SMIM10L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, THUMPD1 is perturbed and the expression of SMIM10L1 is measured. Does this perturbation cause a significant change in SMIM10L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 58262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC9 is perturbed and SHB expression is quantified. Does this perturbation result in a significant change in SHB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC9 is perturbed and SHB expression is quantified. Does this perturbation result in a significant change in SHB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 112891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COX15 and examine the expression of MFSD1. Does perturbing COX15 lead to a significant change in MFSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COX15 and examine the expression of MFSD1. Does perturbing COX15 lead to a significant change in MFSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 50378,"You are a functional genomics specialist. In K562 cells, we perturb TRA2B and monitor DAPK1 expression. Decide whether this perturbation leads to a significant alteration in DAPK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TRA2B and monitor DAPK1 expression. Decide whether this perturbation leads to a significant alteration in DAPK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 103999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISY1 is perturbed and DNAJC24 expression is measured. Determine whether DNAJC24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISY1 is perturbed and DNAJC24 expression is measured. Determine whether DNAJC24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 26401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DPM2 and examine the expression of CLN3. Does perturbing DPM2 lead to a significant change in CLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DPM2 and examine the expression of CLN3. Does perturbing DPM2 lead to a significant change in CLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 111994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3A and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3A and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL46 is associated with a significant change in RPUSD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL46 is associated with a significant change in RPUSD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 9417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3L, does the expression profile of CENPL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3L, does the expression profile of CENPL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 25953,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL12 is perturbed and SNHG17 expression is observed. Does this perturbation lead to a significant difference in SNHG17 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL12 is perturbed and SNHG17 expression is observed. Does this perturbation lead to a significant difference in SNHG17 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 12651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1D and examine the expression of TGFB1. Does perturbing ATP6V1D lead to a significant change in TGFB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1D and examine the expression of TGFB1. Does perturbing ATP6V1D lead to a significant change in TGFB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 7872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO13 is perturbed and YDJC expression is quantified. Does this perturbation result in a significant change in YDJC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO13 is perturbed and YDJC expression is quantified. Does this perturbation result in a significant change in YDJC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 112308,"You are a functional genomics specialist. In K562 cells, we perturb OGT and monitor MYL12B expression. Decide whether this perturbation leads to a significant alteration in MYL12B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb OGT and monitor MYL12B expression. Decide whether this perturbation leads to a significant alteration in MYL12B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 63914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PHB2 and then measure expression of SPP1. Does this perturbation cause a significant change in SPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PHB2 and then measure expression of SPP1. Does this perturbation cause a significant change in SPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 44340,"You are an expert in single-cell biology and functional genomics. In K562 cells, YPEL5 is perturbed and the expression of DMTF1 is measured. Does this perturbation cause a significant change in DMTF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, YPEL5 is perturbed and the expression of DMTF1 is measured. Does this perturbation cause a significant change in DMTF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 87431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL10A and examine the expression of SH3BGRL. Does perturbing RPL10A lead to a significant change in SH3BGRL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL10A and examine the expression of SH3BGRL. Does perturbing RPL10A lead to a significant change in SH3BGRL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 15876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNX15 is perturbed and the expression of SLC25A38 is measured. Determine whether SLC25A38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNX15 is perturbed and the expression of SLC25A38 is measured. Determine whether SLC25A38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 86707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EEFSEC, does the expression profile of H2AFJ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EEFSEC, does the expression profile of H2AFJ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 9801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDCD3 and examine the expression of GPC1. Does perturbing NUDCD3 lead to a significant change in GPC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDCD3 and examine the expression of GPC1. Does perturbing NUDCD3 lead to a significant change in GPC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 81612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG1 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG1 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCAF6 is perturbed and the expression of PEPD is measured. Determine whether PEPD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCAF6 is perturbed and the expression of PEPD is measured. Determine whether PEPD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 37114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL39 and then measure expression of STK38L. Does this perturbation cause a significant change in STK38L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL39 and then measure expression of STK38L. Does this perturbation cause a significant change in STK38L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PGAM5 is perturbed and the expression of TRIM27 is measured. Determine whether TRIM27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PGAM5 is perturbed and the expression of TRIM27 is measured. Determine whether TRIM27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 106545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED7 is associated with a significant change in H2AFY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED7 is associated with a significant change in H2AFY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 25623,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD1 is perturbed and LINC00467 expression is observed. Does this perturbation lead to a significant difference in LINC00467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD1 is perturbed and LINC00467 expression is observed. Does this perturbation lead to a significant difference in LINC00467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 86643,You are an expert in regulatory genomics. Consider data from K562 cells in which CDC42 is perturbed and DNAJC4 expression is observed. Does this perturbation lead to a significant difference in DNAJC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDC42 is perturbed and DNAJC4 expression is observed. Does this perturbation lead to a significant difference in DNAJC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 88388,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor CENPV expression. Decide whether this perturbation leads to a significant alteration in CENPV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor CENPV expression. Decide whether this perturbation leads to a significant alteration in CENPV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 99402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and MOCS2 expression is quantified. Does this perturbation result in a significant change in MOCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and MOCS2 expression is quantified. Does this perturbation result in a significant change in MOCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 54383,You are an expert in regulatory genomics. Consider data from K562 cells in which EWSR1 is perturbed and ZNF766 expression is observed. Does this perturbation lead to a significant difference in ZNF766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EWSR1 is perturbed and ZNF766 expression is observed. Does this perturbation lead to a significant difference in ZNF766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 56461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC1 and examine the expression of SMYD4. Does perturbing TRAPPC1 lead to a significant change in SMYD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC1 and examine the expression of SMYD4. Does perturbing TRAPPC1 lead to a significant change in SMYD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 84061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KAT5 and examine the expression of PTEN. Does perturbing KAT5 lead to a significant change in PTEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KAT5 and examine the expression of PTEN. Does perturbing KAT5 lead to a significant change in PTEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GEMIN4 is perturbed and the expression of CYBRD1 is measured. Determine whether CYBRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GEMIN4 is perturbed and the expression of CYBRD1 is measured. Determine whether CYBRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 101582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1 is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1 is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 17434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDX5 and then measure expression of SP140L. Does this perturbation cause a significant change in SP140L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDX5 and then measure expression of SP140L. Does this perturbation cause a significant change in SP140L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 83929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TCOF1 is perturbed and IL1B expression is measured. Determine whether IL1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TCOF1 is perturbed and IL1B expression is measured. Determine whether IL1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 51216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSGEP is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSGEP is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 42078,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor UTP25 expression. Decide whether this perturbation leads to a significant alteration in UTP25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor UTP25 expression. Decide whether this perturbation leads to a significant alteration in UTP25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 86348,"You are a functional genomics specialist. In K562 cells, we perturb WDR61 and monitor MEST expression. Decide whether this perturbation leads to a significant alteration in MEST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb WDR61 and monitor MEST expression. Decide whether this perturbation leads to a significant alteration in MEST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 82946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL18 is perturbed and the expression of ZC3H12C is measured. Determine whether ZC3H12C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL18 is perturbed and the expression of ZC3H12C is measured. Determine whether ZC3H12C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 70559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PABPC1 is perturbed and VEGFA expression is measured. Determine whether VEGFA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PABPC1 is perturbed and VEGFA expression is measured. Determine whether VEGFA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 16859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NUP160 is perturbed and CREBL2 expression is measured. Determine whether CREBL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NUP160 is perturbed and CREBL2 expression is measured. Determine whether CREBL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 32411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of PPIB. Does perturbing DHDDS lead to a significant change in PPIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of PPIB. Does perturbing DHDDS lead to a significant change in PPIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 25082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KRT8 is perturbed and OSBPL6 expression is quantified. Does this perturbation result in a significant change in OSBPL6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KRT8 is perturbed and OSBPL6 expression is quantified. Does this perturbation result in a significant change in OSBPL6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 74914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDCD7 and then measure expression of GALNT4. Does this perturbation cause a significant change in GALNT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDCD7 and then measure expression of GALNT4. Does this perturbation cause a significant change in GALNT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 109332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEPCE is perturbed and TGIF1 expression is quantified. Does this perturbation result in a significant change in TGIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEPCE is perturbed and TGIF1 expression is quantified. Does this perturbation result in a significant change in TGIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 21258,"You are a functional genomics specialist. In K562 cells, we perturb RBM12 and monitor SCN9A expression. Decide whether this perturbation leads to a significant alteration in SCN9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RBM12 and monitor SCN9A expression. Decide whether this perturbation leads to a significant alteration in SCN9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 41570,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL38 is perturbed and the expression of YIPF5 is measured. Does this perturbation cause a significant change in YIPF5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL38 is perturbed and the expression of YIPF5 is measured. Does this perturbation cause a significant change in YIPF5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 23472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS23 is perturbed and CPOX expression is quantified. Does this perturbation result in a significant change in CPOX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS23 is perturbed and CPOX expression is quantified. Does this perturbation result in a significant change in CPOX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 46743,You are an expert in regulatory genomics. Consider data from K562 cells in which DPH3 is perturbed and MTMR9 expression is observed. Does this perturbation lead to a significant difference in MTMR9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DPH3 is perturbed and MTMR9 expression is observed. Does this perturbation lead to a significant difference in MTMR9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 8634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS25 and then measure expression of PATL1. Does this perturbation cause a significant change in PATL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS25 and then measure expression of PATL1. Does this perturbation cause a significant change in PATL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 107791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SKP1 and examine the expression of IER3IP1. Does perturbing SKP1 lead to a significant change in IER3IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SKP1 and examine the expression of IER3IP1. Does perturbing SKP1 lead to a significant change in IER3IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 91864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX37 and then measure expression of NUDT4. Does this perturbation cause a significant change in NUDT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX37 and then measure expression of NUDT4. Does this perturbation cause a significant change in NUDT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 121567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHMP2A, does the expression profile of TMEM132A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHMP2A, does the expression profile of TMEM132A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 16841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP160 and examine the expression of KIDINS220. Does perturbing NUP160 lead to a significant change in KIDINS220 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP160 and examine the expression of KIDINS220. Does perturbing NUP160 lead to a significant change in KIDINS220 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 54996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAPC3 is perturbed and the expression of SUPV3L1 is measured. Determine whether SUPV3L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAPC3 is perturbed and the expression of SUPV3L1 is measured. Determine whether SUPV3L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 13343,You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C1 is perturbed and YIPF4 expression is observed. Does this perturbation lead to a significant difference in YIPF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C1 is perturbed and YIPF4 expression is observed. Does this perturbation lead to a significant difference in YIPF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 73253,You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C3 is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C3 is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 20621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGLN2 and examine the expression of REEP4. Does perturbing EGLN2 lead to a significant change in REEP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGLN2 and examine the expression of REEP4. Does perturbing EGLN2 lead to a significant change in REEP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 91461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3H and examine the expression of SSX2IP. Does perturbing EIF3H lead to a significant change in SSX2IP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3H and examine the expression of SSX2IP. Does perturbing EIF3H lead to a significant change in SSX2IP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 36221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RCOR1 and examine the expression of MAFF. Does perturbing RCOR1 lead to a significant change in MAFF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RCOR1 and examine the expression of MAFF. Does perturbing RCOR1 lead to a significant change in MAFF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 63528,"You are a functional genomics specialist. In K562 cells, we perturb SRSF3 and monitor GLRB expression. Decide whether this perturbation leads to a significant alteration in GLRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRSF3 and monitor GLRB expression. Decide whether this perturbation leads to a significant alteration in GLRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 105060,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNRNPU is perturbed and the expression of HIBCH is measured. Does this perturbation cause a significant change in HIBCH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNRNPU is perturbed and the expression of HIBCH is measured. Does this perturbation cause a significant change in HIBCH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 72009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PMPCA is perturbed and UPP1 expression is measured. Determine whether UPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PMPCA is perturbed and UPP1 expression is measured. Determine whether UPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDTC1 is perturbed and the expression of ATXN7L3B is measured. Determine whether ATXN7L3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDTC1 is perturbed and the expression of ATXN7L3B is measured. Determine whether ATXN7L3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 61134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RABGGTA and then measure expression of DENND5A. Does this perturbation cause a significant change in DENND5A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RABGGTA and then measure expression of DENND5A. Does this perturbation cause a significant change in DENND5A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 59635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NPM1 is associated with a significant change in TNFRSF10D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NPM1 is associated with a significant change in TNFRSF10D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 28905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC7A5 is associated with a significant change in PA2G4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC7A5 is associated with a significant change in PA2G4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 111927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF4, does the expression profile of VCPIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF4, does the expression profile of VCPIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 21104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDT1 and then measure expression of TNIK. Does this perturbation cause a significant change in TNIK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDT1 and then measure expression of TNIK. Does this perturbation cause a significant change in TNIK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 43606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP2R3C is perturbed and the expression of RBM6 is measured. Determine whether RBM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP2R3C is perturbed and the expression of RBM6 is measured. Determine whether RBM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5068,"You are a functional genomics specialist. In K562 cells, we perturb USP8 and monitor MRPS36 expression. Decide whether this perturbation leads to a significant alteration in MRPS36 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb USP8 and monitor MRPS36 expression. Decide whether this perturbation leads to a significant alteration in MRPS36 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 43664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HERC1 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HERC1 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 80449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATR is perturbed and NDUFAF8 expression is measured. Determine whether NDUFAF8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATR is perturbed and NDUFAF8 expression is measured. Determine whether NDUFAF8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2178,"You are a functional genomics specialist. In K562 cells, we perturb HEATR1 and monitor ZNF3 expression. Decide whether this perturbation leads to a significant alteration in ZNF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HEATR1 and monitor ZNF3 expression. Decide whether this perturbation leads to a significant alteration in ZNF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 86709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EEFSEC is perturbed and H2AFJ expression is measured. Determine whether H2AFJ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EEFSEC is perturbed and H2AFJ expression is measured. Determine whether H2AFJ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MALSU1 is associated with a significant change in NANS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MALSU1 is associated with a significant change in NANS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 43619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP2R3C is perturbed and KDELR3 expression is measured. Determine whether KDELR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP2R3C is perturbed and KDELR3 expression is measured. Determine whether KDELR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 71700,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMC4 is perturbed and the expression of NPC1 is measured. Does this perturbation cause a significant change in NPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMC4 is perturbed and the expression of NPC1 is measured. Does this perturbation cause a significant change in NPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 38225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF11 is associated with a significant change in ANAPC13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF11 is associated with a significant change in ANAPC13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 66424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3I and then measure expression of NXT1. Does this perturbation cause a significant change in NXT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3I and then measure expression of NXT1. Does this perturbation cause a significant change in NXT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 111607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UTP18, does the expression profile of CYLD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UTP18, does the expression profile of CYLD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 20766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACIN1 is perturbed and the expression of EEF1AKNMT is measured. Determine whether EEF1AKNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACIN1 is perturbed and the expression of EEF1AKNMT is measured. Determine whether EEF1AKNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 21942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCTN1 is perturbed and ACTR6 expression is quantified. Does this perturbation result in a significant change in ACTR6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCTN1 is perturbed and ACTR6 expression is quantified. Does this perturbation result in a significant change in ACTR6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 50362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HIRA is perturbed and PNISR expression is quantified. Does this perturbation result in a significant change in PNISR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HIRA is perturbed and PNISR expression is quantified. Does this perturbation result in a significant change in PNISR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 96017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AP2A1, does the expression profile of GALNT10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AP2A1, does the expression profile of GALNT10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 94777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC40, does the expression profile of SGSM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC40, does the expression profile of SGSM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 79195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD13 is associated with a significant change in TTLL7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD13 is associated with a significant change in TTLL7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 86103,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5ME is perturbed and IPO4 expression is observed. Does this perturbation lead to a significant difference in IPO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5ME is perturbed and IPO4 expression is observed. Does this perturbation lead to a significant difference in IPO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 16075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3B5 is associated with a significant change in NADSYN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3B5 is associated with a significant change in NADSYN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 42948,"You are a functional genomics specialist. In K562 cells, we perturb LTBP3 and monitor CRIP2 expression. Decide whether this perturbation leads to a significant alteration in CRIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LTBP3 and monitor CRIP2 expression. Decide whether this perturbation leads to a significant alteration in CRIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 24232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPAP2 is perturbed and PHF3 expression is quantified. Does this perturbation result in a significant change in PHF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPAP2 is perturbed and PHF3 expression is quantified. Does this perturbation result in a significant change in PHF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 68127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UQCRB, does the expression profile of KRIT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UQCRB, does the expression profile of KRIT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 54235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX19B is associated with a significant change in SUSD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX19B is associated with a significant change in SUSD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 11882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RNF103 is perturbed and PAF1 expression is quantified. Does this perturbation result in a significant change in PAF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RNF103 is perturbed and PAF1 expression is quantified. Does this perturbation result in a significant change in PAF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 47080,"You are an expert in single-cell biology and functional genomics. In K562 cells, RABGGTB is perturbed and the expression of CMPK1 is measured. Does this perturbation cause a significant change in CMPK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RABGGTB is perturbed and the expression of CMPK1 is measured. Does this perturbation cause a significant change in CMPK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 91519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL42 is perturbed and MLXIP expression is measured. Determine whether MLXIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL42 is perturbed and MLXIP expression is measured. Determine whether MLXIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 7980,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF3 is perturbed and the expression of PEBP1 is measured. Does this perturbation cause a significant change in PEBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF3 is perturbed and the expression of PEBP1 is measured. Does this perturbation cause a significant change in PEBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 68954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBA2 and then measure expression of KLHL21. Does this perturbation cause a significant change in KLHL21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBA2 and then measure expression of KLHL21. Does this perturbation cause a significant change in KLHL21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 9797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRRC2A, does the expression profile of COX11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRRC2A, does the expression profile of COX11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 17316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL32 is perturbed and the expression of TMEM19 is measured. Determine whether TMEM19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL32 is perturbed and the expression of TMEM19 is measured. Determine whether TMEM19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 12492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KPNA6 is perturbed and RTL8C expression is quantified. Does this perturbation result in a significant change in RTL8C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KPNA6 is perturbed and RTL8C expression is quantified. Does this perturbation result in a significant change in RTL8C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 30741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM4 and examine the expression of VGLL4. Does perturbing LSM4 lead to a significant change in VGLL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM4 and examine the expression of VGLL4. Does perturbing LSM4 lead to a significant change in VGLL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 10369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VARS is perturbed and GAS5 expression is measured. Determine whether GAS5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VARS is perturbed and GAS5 expression is measured. Determine whether GAS5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 31013,You are an expert in regulatory genomics. Consider data from K562 cells in which MAD2L2 is perturbed and MED28 expression is observed. Does this perturbation lead to a significant difference in MED28 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAD2L2 is perturbed and MED28 expression is observed. Does this perturbation lead to a significant difference in MED28 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1503,You are an expert in regulatory genomics. Consider data from K562 cells in which CCDC6 is perturbed and COPS3 expression is observed. Does this perturbation lead to a significant difference in COPS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CCDC6 is perturbed and COPS3 expression is observed. Does this perturbation lead to a significant difference in COPS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 29234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF6 and then measure expression of TMEM99. Does this perturbation cause a significant change in TMEM99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF6 and then measure expression of TMEM99. Does this perturbation cause a significant change in TMEM99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 49391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BDP1 and examine the expression of TAOK1. Does perturbing BDP1 lead to a significant change in TAOK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BDP1 and examine the expression of TAOK1. Does perturbing BDP1 lead to a significant change in TAOK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 114399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FAM32A is perturbed and PTPN2 expression is measured. Determine whether PTPN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FAM32A is perturbed and PTPN2 expression is measured. Determine whether PTPN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 121514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FIP1L1 and then measure expression of SUMF1. Does this perturbation cause a significant change in SUMF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FIP1L1 and then measure expression of SUMF1. Does this perturbation cause a significant change in SUMF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 31566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELL is perturbed and the expression of CRYZ is measured. Determine whether CRYZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELL is perturbed and the expression of CRYZ is measured. Determine whether CRYZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 113912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX21 is perturbed and ACAP2 expression is quantified. Does this perturbation result in a significant change in ACAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX21 is perturbed and ACAP2 expression is quantified. Does this perturbation result in a significant change in ACAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 32335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ADSL is associated with a significant change in FANCD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ADSL is associated with a significant change in FANCD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 7415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4E is associated with a significant change in PLGRKT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4E is associated with a significant change in PLGRKT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 64509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HAUS6 is perturbed and SNAPC1 expression is measured. Determine whether SNAPC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HAUS6 is perturbed and SNAPC1 expression is measured. Determine whether SNAPC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2148,"You are a functional genomics specialist. In K562 cells, we perturb HEATR1 and monitor ACTA2 expression. Decide whether this perturbation leads to a significant alteration in ACTA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HEATR1 and monitor ACTA2 expression. Decide whether this perturbation leads to a significant alteration in ACTA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 115903,You are an expert in regulatory genomics. Consider data from K562 cells in which SDE2 is perturbed and ZMAT2 expression is observed. Does this perturbation lead to a significant difference in ZMAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SDE2 is perturbed and ZMAT2 expression is observed. Does this perturbation lead to a significant difference in ZMAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 96443,You are an expert in regulatory genomics. Consider data from K562 cells in which NHP2 is perturbed and HIPK2 expression is observed. Does this perturbation lead to a significant difference in HIPK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NHP2 is perturbed and HIPK2 expression is observed. Does this perturbation lead to a significant difference in HIPK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 44704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EDC4 and then measure expression of JUP. Does this perturbation cause a significant change in JUP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EDC4 and then measure expression of JUP. Does this perturbation cause a significant change in JUP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 112905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COX15 is associated with a significant change in SPSB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COX15 is associated with a significant change in SPSB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGS1 and examine the expression of TTLL5. Does perturbing PGS1 lead to a significant change in TTLL5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGS1 and examine the expression of TTLL5. Does perturbing PGS1 lead to a significant change in TTLL5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3H13 is perturbed and NRP2 expression is measured. Determine whether NRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3H13 is perturbed and NRP2 expression is measured. Determine whether NRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 32823,You are an expert in regulatory genomics. Consider data from K562 cells in which PRXL2A is perturbed and SLC39A1 expression is observed. Does this perturbation lead to a significant difference in SLC39A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PRXL2A is perturbed and SLC39A1 expression is observed. Does this perturbation lead to a significant difference in SLC39A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 121802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PEX1 is perturbed and YBEY expression is quantified. Does this perturbation result in a significant change in YBEY expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PEX1 is perturbed and YBEY expression is quantified. Does this perturbation result in a significant change in YBEY expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 56984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL4 and then measure expression of TMEM99. Does this perturbation cause a significant change in TMEM99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL4 and then measure expression of TMEM99. Does this perturbation cause a significant change in TMEM99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 59287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TEX10, does the expression profile of WBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TEX10, does the expression profile of WBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 87835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS29 is associated with a significant change in POFUT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS29 is associated with a significant change in POFUT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 102746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GSPT1 is perturbed and the expression of B4GALT5 is measured. Determine whether B4GALT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GSPT1 is perturbed and the expression of B4GALT5 is measured. Determine whether B4GALT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 39902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRMT5 is perturbed and RGS12 expression is quantified. Does this perturbation result in a significant change in RGS12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRMT5 is perturbed and RGS12 expression is quantified. Does this perturbation result in a significant change in RGS12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 11181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC3 and examine the expression of PLK2. Does perturbing THOC3 lead to a significant change in PLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC3 and examine the expression of PLK2. Does perturbing THOC3 lead to a significant change in PLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 105157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPT6H, does the expression profile of SLC25A29 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPT6H, does the expression profile of SLC25A29 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 94482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TLN1 is perturbed and KIFAP3 expression is quantified. Does this perturbation result in a significant change in KIFAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TLN1 is perturbed and KIFAP3 expression is quantified. Does this perturbation result in a significant change in KIFAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 109348,"You are a functional genomics specialist. In K562 cells, we perturb MEPCE and monitor ACADSB expression. Decide whether this perturbation leads to a significant alteration in ACADSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MEPCE and monitor ACADSB expression. Decide whether this perturbation leads to a significant alteration in ACADSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 31170,"You are an expert in single-cell biology and functional genomics. In K562 cells, CTDP1 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CTDP1 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 18456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RTCB is perturbed and the expression of RETREG1 is measured. Determine whether RETREG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RTCB is perturbed and the expression of RETREG1 is measured. Determine whether RETREG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 105098,"You are a functional genomics specialist. In K562 cells, we perturb HNRNPU and monitor DNAJB11 expression. Decide whether this perturbation leads to a significant alteration in DNAJB11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HNRNPU and monitor DNAJB11 expression. Decide whether this perturbation leads to a significant alteration in DNAJB11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 32328,"You are a functional genomics specialist. In K562 cells, we perturb ADSL and monitor ECHS1 expression. Decide whether this perturbation leads to a significant alteration in ECHS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ADSL and monitor ECHS1 expression. Decide whether this perturbation leads to a significant alteration in ECHS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 114680,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNL3L is perturbed and the expression of TSPAN5 is measured. Does this perturbation cause a significant change in TSPAN5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNL3L is perturbed and the expression of TSPAN5 is measured. Does this perturbation cause a significant change in TSPAN5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 109638,"You are a functional genomics specialist. In K562 cells, we perturb MCM7 and monitor MXD4 expression. Decide whether this perturbation leads to a significant alteration in MXD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MCM7 and monitor MXD4 expression. Decide whether this perturbation leads to a significant alteration in MXD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 87320,"You are an expert in single-cell biology and functional genomics. In K562 cells, DRAP1 is perturbed and the expression of RABGGTA is measured. Does this perturbation cause a significant change in RABGGTA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DRAP1 is perturbed and the expression of RABGGTA is measured. Does this perturbation cause a significant change in RABGGTA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 118926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of TGFBR2 is measured. Determine whether TGFBR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of TGFBR2 is measured. Determine whether TGFBR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 57045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PKMYT1 is associated with a significant change in PIP4K2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PKMYT1 is associated with a significant change in PIP4K2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 83264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUS1 and then measure expression of DDX20. Does this perturbation cause a significant change in DDX20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUS1 and then measure expression of DDX20. Does this perturbation cause a significant change in DDX20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 34732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NOL8 is perturbed and SLC35C1 expression is quantified. Does this perturbation result in a significant change in SLC35C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NOL8 is perturbed and SLC35C1 expression is quantified. Does this perturbation result in a significant change in SLC35C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 44028,"You are a functional genomics specialist. In K562 cells, we perturb ELP3 and monitor GPR176 expression. Decide whether this perturbation leads to a significant alteration in GPR176 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ELP3 and monitor GPR176 expression. Decide whether this perturbation leads to a significant alteration in GPR176 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 36604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUD31 and then measure expression of NFE2L1. Does this perturbation cause a significant change in NFE2L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUD31 and then measure expression of NFE2L1. Does this perturbation cause a significant change in NFE2L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 108342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMC5 is perturbed and NKTR expression is quantified. Does this perturbation result in a significant change in NKTR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMC5 is perturbed and NKTR expression is quantified. Does this perturbation result in a significant change in NKTR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 49813,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and EOGT expression is observed. Does this perturbation lead to a significant difference in EOGT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and EOGT expression is observed. Does this perturbation lead to a significant difference in EOGT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 24937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX19A, does the expression profile of ENOSF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX19A, does the expression profile of ENOSF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 62861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PNN and examine the expression of SLC17A5. Does perturbing PNN lead to a significant change in SLC17A5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PNN and examine the expression of SLC17A5. Does perturbing PNN lead to a significant change in SLC17A5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 33793,You are an expert in regulatory genomics. Consider data from K562 cells in which CACNB3 is perturbed and CC2D1A expression is observed. Does this perturbation lead to a significant difference in CC2D1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CACNB3 is perturbed and CC2D1A expression is observed. Does this perturbation lead to a significant difference in CC2D1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 21041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBR5 and examine the expression of KIAA1522. Does perturbing UBR5 lead to a significant change in KIAA1522 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBR5 and examine the expression of KIAA1522. Does perturbing UBR5 lead to a significant change in KIAA1522 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 25586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UCHL5 is perturbed and the expression of ZKSCAN1 is measured. Determine whether ZKSCAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UCHL5 is perturbed and the expression of ZKSCAN1 is measured. Determine whether ZKSCAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 66360,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSME2 is perturbed and the expression of ARID2 is measured. Does this perturbation cause a significant change in ARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSME2 is perturbed and the expression of ARID2 is measured. Does this perturbation cause a significant change in ARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 11009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GAR1 is perturbed and TMEM179B expression is measured. Determine whether TMEM179B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GAR1 is perturbed and TMEM179B expression is measured. Determine whether TMEM179B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 33380,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS2 is perturbed and the expression of RNF121 is measured. Does this perturbation cause a significant change in RNF121 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS2 is perturbed and the expression of RNF121 is measured. Does this perturbation cause a significant change in RNF121 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 92396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS17 is perturbed and the expression of WIPF2 is measured. Determine whether WIPF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS17 is perturbed and the expression of WIPF2 is measured. Determine whether WIPF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 19214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UPF2 and then measure expression of RALGAPA1. Does this perturbation cause a significant change in RALGAPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UPF2 and then measure expression of RALGAPA1. Does this perturbation cause a significant change in RALGAPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 107729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and UTP23 expression is measured. Determine whether UTP23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and UTP23 expression is measured. Determine whether UTP23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 35731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CFDP1 and examine the expression of BDNF. Does perturbing CFDP1 lead to a significant change in BDNF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CFDP1 and examine the expression of BDNF. Does perturbing CFDP1 lead to a significant change in BDNF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 97460,"You are an expert in single-cell biology and functional genomics. In K562 cells, NF1 is perturbed and the expression of NUP188 is measured. Does this perturbation cause a significant change in NUP188 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NF1 is perturbed and the expression of NUP188 is measured. Does this perturbation cause a significant change in NUP188 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 23089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHTOP is perturbed and RAB4A expression is measured. Determine whether RAB4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHTOP is perturbed and RAB4A expression is measured. Determine whether RAB4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 67990,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR83OS is perturbed and the expression of B4GAT1 is measured. Does this perturbation cause a significant change in B4GAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR83OS is perturbed and the expression of B4GAT1 is measured. Does this perturbation cause a significant change in B4GAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 13304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUP153 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUP153 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 116632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POT1 is perturbed and AK1 expression is quantified. Does this perturbation result in a significant change in AK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POT1 is perturbed and AK1 expression is quantified. Does this perturbation result in a significant change in AK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 47046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, METTL3 is perturbed and the expression of NISCH is measured. Determine whether NISCH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, METTL3 is perturbed and the expression of NISCH is measured. Determine whether NISCH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 40079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRPF38A is perturbed and DYNLL2 expression is measured. Determine whether DYNLL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRPF38A is perturbed and DYNLL2 expression is measured. Determine whether DYNLL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 79567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP43, does the expression profile of BDNF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP43, does the expression profile of BDNF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 29553,You are an expert in regulatory genomics. Consider data from K562 cells in which MED19 is perturbed and MKLN1 expression is observed. Does this perturbation lead to a significant difference in MKLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MED19 is perturbed and MKLN1 expression is observed. Does this perturbation lead to a significant difference in MKLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 68400,"You are an expert in single-cell biology and functional genomics. In K562 cells, RBM28 is perturbed and the expression of STX6 is measured. Does this perturbation cause a significant change in STX6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RBM28 is perturbed and the expression of STX6 is measured. Does this perturbation cause a significant change in STX6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 69789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and NUCB2 expression is measured. Determine whether NUCB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and NUCB2 expression is measured. Determine whether NUCB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 112674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YAE1 and then measure expression of MGST2. Does this perturbation cause a significant change in MGST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YAE1 and then measure expression of MGST2. Does this perturbation cause a significant change in MGST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TFAM and examine the expression of RBM18. Does perturbing TFAM lead to a significant change in RBM18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TFAM and examine the expression of RBM18. Does perturbing TFAM lead to a significant change in RBM18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 47732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLEKHN1 is perturbed and GPC6 expression is quantified. Does this perturbation result in a significant change in GPC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLEKHN1 is perturbed and GPC6 expression is quantified. Does this perturbation result in a significant change in GPC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 60568,"You are a functional genomics specialist. In K562 cells, we perturb HNRNPM and monitor LATS1 expression. Decide whether this perturbation leads to a significant alteration in LATS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HNRNPM and monitor LATS1 expression. Decide whether this perturbation leads to a significant alteration in LATS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 111533,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF4A1 is perturbed and CPEB4 expression is observed. Does this perturbation lead to a significant difference in CPEB4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF4A1 is perturbed and CPEB4 expression is observed. Does this perturbation lead to a significant difference in CPEB4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 60589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPM is perturbed and NTPCR expression is measured. Determine whether NTPCR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPM is perturbed and NTPCR expression is measured. Determine whether NTPCR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPA1 is perturbed and ANXA3 expression is quantified. Does this perturbation result in a significant change in ANXA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPA1 is perturbed and ANXA3 expression is quantified. Does this perturbation result in a significant change in ANXA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 22751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC13 and examine the expression of DNAJC4. Does perturbing ANAPC13 lead to a significant change in DNAJC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC13 and examine the expression of DNAJC4. Does perturbing ANAPC13 lead to a significant change in DNAJC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 122827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BARD1, does the expression profile of FBLIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BARD1, does the expression profile of FBLIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 112105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRTO4 is associated with a significant change in PMP22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRTO4 is associated with a significant change in PMP22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 16300,"You are an expert in single-cell biology and functional genomics. In K562 cells, TCP1 is perturbed and the expression of ITGAV is measured. Does this perturbation cause a significant change in ITGAV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TCP1 is perturbed and the expression of ITGAV is measured. Does this perturbation cause a significant change in ITGAV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 98133,You are an expert in regulatory genomics. Consider data from K562 cells in which GABPB1 is perturbed and PRRC2B expression is observed. Does this perturbation lead to a significant difference in PRRC2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GABPB1 is perturbed and PRRC2B expression is observed. Does this perturbation lead to a significant difference in PRRC2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 9479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB10 is perturbed and PDLIM1 expression is measured. Determine whether PDLIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB10 is perturbed and PDLIM1 expression is measured. Determine whether PDLIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRNT1 is perturbed and FBXO25 expression is quantified. Does this perturbation result in a significant change in FBXO25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRNT1 is perturbed and FBXO25 expression is quantified. Does this perturbation result in a significant change in FBXO25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 119968,"You are a functional genomics specialist. In K562 cells, we perturb SNAPC1 and monitor TOR1AIP1 expression. Decide whether this perturbation leads to a significant alteration in TOR1AIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SNAPC1 and monitor TOR1AIP1 expression. Decide whether this perturbation leads to a significant alteration in TOR1AIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 59831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SSU72 and examine the expression of CCNDBP1. Does perturbing SSU72 lead to a significant change in CCNDBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SSU72 and examine the expression of CCNDBP1. Does perturbing SSU72 lead to a significant change in CCNDBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 20842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDCD5 is perturbed and MXD4 expression is quantified. Does this perturbation result in a significant change in MXD4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDCD5 is perturbed and MXD4 expression is quantified. Does this perturbation result in a significant change in MXD4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 23438,"You are a functional genomics specialist. In K562 cells, we perturb HSCB and monitor PIP5K1C expression. Decide whether this perturbation leads to a significant alteration in PIP5K1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSCB and monitor PIP5K1C expression. Decide whether this perturbation leads to a significant alteration in PIP5K1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 15868,"You are a functional genomics specialist. In K562 cells, we perturb RIOK1 and monitor ELP1 expression. Decide whether this perturbation leads to a significant alteration in ELP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RIOK1 and monitor ELP1 expression. Decide whether this perturbation leads to a significant alteration in ELP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MCL1 is perturbed and the expression of IDH2 is measured. Determine whether IDH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MCL1 is perturbed and the expression of IDH2 is measured. Determine whether IDH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 10967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRMT5, does the expression profile of RBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRMT5, does the expression profile of RBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MYBBP1A is perturbed and PRDX5 expression is quantified. Does this perturbation result in a significant change in PRDX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MYBBP1A is perturbed and PRDX5 expression is quantified. Does this perturbation result in a significant change in PRDX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 35148,"You are a functional genomics specialist. In K562 cells, we perturb TEAD3 and monitor TMEM101 expression. Decide whether this perturbation leads to a significant alteration in TMEM101 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TEAD3 and monitor TMEM101 expression. Decide whether this perturbation leads to a significant alteration in TMEM101 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 90988,"You are a functional genomics specialist. In K562 cells, we perturb HMGCR and monitor TMEM233 expression. Decide whether this perturbation leads to a significant alteration in TMEM233 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HMGCR and monitor TMEM233 expression. Decide whether this perturbation leads to a significant alteration in TMEM233 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 83426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBE3C is perturbed and the expression of COG6 is measured. Determine whether COG6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBE3C is perturbed and the expression of COG6 is measured. Determine whether COG6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 37100,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL39 is perturbed and the expression of EIF1B is measured. Does this perturbation cause a significant change in EIF1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL39 is perturbed and the expression of EIF1B is measured. Does this perturbation cause a significant change in EIF1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 114148,"You are a functional genomics specialist. In K562 cells, we perturb ADNP2 and monitor TOPORS expression. Decide whether this perturbation leads to a significant alteration in TOPORS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ADNP2 and monitor TOPORS expression. Decide whether this perturbation leads to a significant alteration in TOPORS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 55686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRS1 is perturbed and the expression of UBE2L3 is measured. Determine whether UBE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRS1 is perturbed and the expression of UBE2L3 is measured. Determine whether UBE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 61903,You are an expert in regulatory genomics. Consider data from K562 cells in which DBF4 is perturbed and LAPTM4B expression is observed. Does this perturbation lead to a significant difference in LAPTM4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DBF4 is perturbed and LAPTM4B expression is observed. Does this perturbation lead to a significant difference in LAPTM4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 99714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBL5 and then measure expression of BAZ2A. Does this perturbation cause a significant change in BAZ2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBL5 and then measure expression of BAZ2A. Does this perturbation cause a significant change in BAZ2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 14952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TOMM20 is perturbed and STAMBP expression is quantified. Does this perturbation result in a significant change in STAMBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TOMM20 is perturbed and STAMBP expression is quantified. Does this perturbation result in a significant change in STAMBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 26377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MMS19, does the expression profile of RBM42 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MMS19, does the expression profile of RBM42 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 40712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SETX is perturbed and ARFGAP2 expression is quantified. Does this perturbation result in a significant change in ARFGAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SETX is perturbed and ARFGAP2 expression is quantified. Does this perturbation result in a significant change in ARFGAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 92290,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCT8 is perturbed and the expression of RHOD is measured. Does this perturbation cause a significant change in RHOD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCT8 is perturbed and the expression of RHOD is measured. Does this perturbation cause a significant change in RHOD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 7509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L1 is perturbed and CD68 expression is measured. Determine whether CD68 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L1 is perturbed and CD68 expression is measured. Determine whether CD68 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 113130,"You are an expert in single-cell biology and functional genomics. In K562 cells, SKA3 is perturbed and the expression of ROBO1 is measured. Does this perturbation cause a significant change in ROBO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SKA3 is perturbed and the expression of ROBO1 is measured. Does this perturbation cause a significant change in ROBO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 79424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF236 and then measure expression of FBXW7. Does this perturbation cause a significant change in FBXW7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF236 and then measure expression of FBXW7. Does this perturbation cause a significant change in FBXW7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 91764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CRKL and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CRKL and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 17602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MCMBP is perturbed and TMEM200A expression is quantified. Does this perturbation result in a significant change in TMEM200A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MCMBP is perturbed and TMEM200A expression is quantified. Does this perturbation result in a significant change in TMEM200A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 73783,You are an expert in regulatory genomics. Consider data from K562 cells in which SP2 is perturbed and ANKMY2 expression is observed. Does this perturbation lead to a significant difference in ANKMY2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SP2 is perturbed and ANKMY2 expression is observed. Does this perturbation lead to a significant difference in ANKMY2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 27663,You are an expert in regulatory genomics. Consider data from K562 cells in which COPS6 is perturbed and PLXNA1 expression is observed. Does this perturbation lead to a significant difference in PLXNA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPS6 is perturbed and PLXNA1 expression is observed. Does this perturbation lead to a significant difference in PLXNA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 88112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UPF1 is perturbed and DNAJC17 expression is quantified. Does this perturbation result in a significant change in DNAJC17 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UPF1 is perturbed and DNAJC17 expression is quantified. Does this perturbation result in a significant change in DNAJC17 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 103207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of PREPL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of PREPL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 48623,You are an expert in regulatory genomics. Consider data from K562 cells in which SMU1 is perturbed and PEX26 expression is observed. Does this perturbation lead to a significant difference in PEX26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SMU1 is perturbed and PEX26 expression is observed. Does this perturbation lead to a significant difference in PEX26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 17415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACTR1A is associated with a significant change in ERI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACTR1A is associated with a significant change in ERI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 101906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of CCDC22 is measured. Determine whether CCDC22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of CCDC22 is measured. Determine whether CCDC22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 108186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PIK3R4 is perturbed and the expression of MIR181A1HG is measured. Determine whether MIR181A1HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PIK3R4 is perturbed and the expression of MIR181A1HG is measured. Determine whether MIR181A1HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 96417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NHP2, does the expression profile of GPRC5C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NHP2, does the expression profile of GPRC5C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 109897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS10, does the expression profile of ARL5A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS10, does the expression profile of ARL5A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 37463,You are an expert in regulatory genomics. Consider data from K562 cells in which HNRNPK is perturbed and KANSL1 expression is observed. Does this perturbation lead to a significant difference in KANSL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HNRNPK is perturbed and KANSL1 expression is observed. Does this perturbation lead to a significant difference in KANSL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 41936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX3X is perturbed and the expression of ANKRD13D is measured. Determine whether ANKRD13D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX3X is perturbed and the expression of ANKRD13D is measured. Determine whether ANKRD13D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 70894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD10 and then measure expression of GTPBP6. Does this perturbation cause a significant change in GTPBP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD10 and then measure expression of GTPBP6. Does this perturbation cause a significant change in GTPBP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 116924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL45 and then measure expression of RPL10. Does this perturbation cause a significant change in RPL10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL45 and then measure expression of RPL10. Does this perturbation cause a significant change in RPL10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 79524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL55 and then measure expression of SPG7. Does this perturbation cause a significant change in SPG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL55 and then measure expression of SPG7. Does this perturbation cause a significant change in SPG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 35110,"You are an expert in single-cell biology and functional genomics. In K562 cells, TEAD3 is perturbed and the expression of HAUS3 is measured. Does this perturbation cause a significant change in HAUS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TEAD3 is perturbed and the expression of HAUS3 is measured. Does this perturbation cause a significant change in HAUS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 82740,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX29 is perturbed and the expression of PBX3 is measured. Does this perturbation cause a significant change in PBX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX29 is perturbed and the expression of PBX3 is measured. Does this perturbation cause a significant change in PBX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 18416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YRDC is perturbed and the expression of POLR2G is measured. Determine whether POLR2G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YRDC is perturbed and the expression of POLR2G is measured. Determine whether POLR2G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 70978,"You are a functional genomics specialist. In K562 cells, we perturb COX6C and monitor ZFYVE9 expression. Decide whether this perturbation leads to a significant alteration in ZFYVE9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COX6C and monitor ZFYVE9 expression. Decide whether this perturbation leads to a significant alteration in ZFYVE9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 52989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARPC2 is perturbed and PPIB expression is measured. Determine whether PPIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARPC2 is perturbed and PPIB expression is measured. Determine whether PPIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 46569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NELFCD is perturbed and SINHCAF expression is measured. Determine whether SINHCAF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NELFCD is perturbed and SINHCAF expression is measured. Determine whether SINHCAF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 88421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SP2. Does perturbing MTHFD1 lead to a significant change in SP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SP2. Does perturbing MTHFD1 lead to a significant change in SP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 18645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPMT1 is associated with a significant change in ST7L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPMT1 is associated with a significant change in ST7L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 41241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCDC137 and examine the expression of GOLGB1. Does perturbing CCDC137 lead to a significant change in GOLGB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCDC137 and examine the expression of GOLGB1. Does perturbing CCDC137 lead to a significant change in GOLGB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 101849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHMP7 is perturbed and TSPAN4 expression is measured. Determine whether TSPAN4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHMP7 is perturbed and TSPAN4 expression is measured. Determine whether TSPAN4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 30620,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBE2H is perturbed and the expression of AKT2 is measured. Does this perturbation cause a significant change in AKT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBE2H is perturbed and the expression of AKT2 is measured. Does this perturbation cause a significant change in AKT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 27319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FBLIM1 is perturbed and BORCS8 expression is measured. Determine whether BORCS8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FBLIM1 is perturbed and BORCS8 expression is measured. Determine whether BORCS8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 77094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC1 and then measure expression of FUCA2. Does this perturbation cause a significant change in FUCA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC1 and then measure expression of FUCA2. Does this perturbation cause a significant change in FUCA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 37324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RBMX and then measure expression of NIPSNAP1. Does this perturbation cause a significant change in NIPSNAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RBMX and then measure expression of NIPSNAP1. Does this perturbation cause a significant change in NIPSNAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 17204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC8 and then measure expression of LPCAT1. Does this perturbation cause a significant change in LPCAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC8 and then measure expression of LPCAT1. Does this perturbation cause a significant change in LPCAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 71680,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDK9 is perturbed and the expression of SNAI1 is measured. Does this perturbation cause a significant change in SNAI1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDK9 is perturbed and the expression of SNAI1 is measured. Does this perturbation cause a significant change in SNAI1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 82137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GEMIN8, does the expression profile of AIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GEMIN8, does the expression profile of AIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 121366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of GNB4 is measured. Determine whether GNB4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of GNB4 is measured. Determine whether GNB4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 31787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPME1, does the expression profile of RPS15A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPME1, does the expression profile of RPS15A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 32467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of TTC37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of TTC37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 370,"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR2D is perturbed and the expression of AP5B1 is measured. Does this perturbation cause a significant change in AP5B1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR2D is perturbed and the expression of AP5B1 is measured. Does this perturbation cause a significant change in AP5B1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 82254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMG2 and then measure expression of BLCAP. Does this perturbation cause a significant change in BLCAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMG2 and then measure expression of BLCAP. Does this perturbation cause a significant change in BLCAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 35081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PABPC4 and examine the expression of SNX29. Does perturbing PABPC4 lead to a significant change in SNX29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PABPC4 and examine the expression of SNX29. Does perturbing PABPC4 lead to a significant change in SNX29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 49666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GUK1 is perturbed and the expression of GATA6 is measured. Determine whether GATA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GUK1 is perturbed and the expression of GATA6 is measured. Determine whether GATA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 108041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CYFIP1 and examine the expression of MBD5. Does perturbing CYFIP1 lead to a significant change in MBD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CYFIP1 and examine the expression of MBD5. Does perturbing CYFIP1 lead to a significant change in MBD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 71674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK9 and then measure expression of PHC3. Does this perturbation cause a significant change in PHC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK9 and then measure expression of PHC3. Does this perturbation cause a significant change in PHC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 84950,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS20 is perturbed and the expression of GINM1 is measured. Does this perturbation cause a significant change in GINM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS20 is perturbed and the expression of GINM1 is measured. Does this perturbation cause a significant change in GINM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 55841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of TAF1B. Does perturbing MRPL39 lead to a significant change in TAF1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of TAF1B. Does perturbing MRPL39 lead to a significant change in TAF1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 32972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPE1 is perturbed and RNPEP expression is quantified. Does this perturbation result in a significant change in RNPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPE1 is perturbed and RNPEP expression is quantified. Does this perturbation result in a significant change in RNPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 40777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPP1CA, does the expression profile of ZNF672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPP1CA, does the expression profile of ZNF672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 120045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX10 is associated with a significant change in PREPL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX10 is associated with a significant change in PREPL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 111058,"You are a functional genomics specialist. In K562 cells, we perturb LDB1 and monitor AASS expression. Decide whether this perturbation leads to a significant alteration in AASS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LDB1 and monitor AASS expression. Decide whether this perturbation leads to a significant alteration in AASS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 72690,"You are an expert in single-cell biology and functional genomics. In K562 cells, OPA1 is perturbed and the expression of UBE3B is measured. Does this perturbation cause a significant change in UBE3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, OPA1 is perturbed and the expression of UBE3B is measured. Does this perturbation cause a significant change in UBE3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 40594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ALYREF and then measure expression of ANXA6. Does this perturbation cause a significant change in ANXA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ALYREF and then measure expression of ANXA6. Does this perturbation cause a significant change in ANXA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 20589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PHAX is perturbed and FAM200B expression is measured. Determine whether FAM200B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PHAX is perturbed and FAM200B expression is measured. Determine whether FAM200B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 85581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RMI1 and examine the expression of TRMU. Does perturbing RMI1 lead to a significant change in TRMU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RMI1 and examine the expression of TRMU. Does perturbing RMI1 lead to a significant change in TRMU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 91137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PFDN2, does the expression profile of YIPF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PFDN2, does the expression profile of YIPF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 121908,"You are a functional genomics specialist. In K562 cells, we perturb THUMPD1 and monitor SMIM10L1 expression. Decide whether this perturbation leads to a significant alteration in SMIM10L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb THUMPD1 and monitor SMIM10L1 expression. Decide whether this perturbation leads to a significant alteration in SMIM10L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 120473,You are an expert in regulatory genomics. Consider data from K562 cells in which SOD1 is perturbed and CDK5RAP1 expression is observed. Does this perturbation lead to a significant difference in CDK5RAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SOD1 is perturbed and CDK5RAP1 expression is observed. Does this perturbation lead to a significant difference in CDK5RAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 117727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC26, does the expression profile of SYNGR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC26, does the expression profile of SYNGR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 82787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHX29, does the expression profile of ATP6V0A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHX29, does the expression profile of ATP6V0A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 19100,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLI4 is perturbed and the expression of URGCP is measured. Does this perturbation cause a significant change in URGCP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLI4 is perturbed and the expression of URGCP is measured. Does this perturbation cause a significant change in URGCP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 9395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3L is associated with a significant change in SH3D19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3L is associated with a significant change in SH3D19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 116814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPIE and then measure expression of ETV5. Does this perturbation cause a significant change in ETV5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPIE and then measure expression of ETV5. Does this perturbation cause a significant change in ETV5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 120981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLBP and examine the expression of PIGM. Does perturbing SLBP lead to a significant change in PIGM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLBP and examine the expression of PIGM. Does perturbing SLBP lead to a significant change in PIGM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 90240,"You are an expert in single-cell biology and functional genomics. In K562 cells, ANKRD17 is perturbed and the expression of IP6K2 is measured. Does this perturbation cause a significant change in IP6K2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ANKRD17 is perturbed and the expression of IP6K2 is measured. Does this perturbation cause a significant change in IP6K2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 61836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL35A is perturbed and the expression of SAMD1 is measured. Determine whether SAMD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL35A is perturbed and the expression of SAMD1 is measured. Determine whether SAMD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 91900,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX37 is perturbed and the expression of SH3D21 is measured. Does this perturbation cause a significant change in SH3D21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX37 is perturbed and the expression of SH3D21 is measured. Does this perturbation cause a significant change in SH3D21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 108208,"You are a functional genomics specialist. In K562 cells, we perturb PIK3R4 and monitor FAM149B1 expression. Decide whether this perturbation leads to a significant alteration in FAM149B1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PIK3R4 and monitor FAM149B1 expression. Decide whether this perturbation leads to a significant alteration in FAM149B1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 106501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED7 and examine the expression of SEC22B. Does perturbing MED7 lead to a significant change in SEC22B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED7 and examine the expression of SEC22B. Does perturbing MED7 lead to a significant change in SEC22B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HAUS3 is perturbed and CRNKL1 expression is quantified. Does this perturbation result in a significant change in CRNKL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HAUS3 is perturbed and CRNKL1 expression is quantified. Does this perturbation result in a significant change in CRNKL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 21774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MMGT1 and then measure expression of IK. Does this perturbation cause a significant change in IK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MMGT1 and then measure expression of IK. Does this perturbation cause a significant change in IK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 48241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT3 and examine the expression of ZDHHC8. Does perturbing ZNHIT3 lead to a significant change in ZDHHC8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT3 and examine the expression of ZDHHC8. Does perturbing ZNHIT3 lead to a significant change in ZDHHC8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 67408,"You are a functional genomics specialist. In K562 cells, we perturb VPS29 and monitor SLC35B3 expression. Decide whether this perturbation leads to a significant alteration in SLC35B3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb VPS29 and monitor SLC35B3 expression. Decide whether this perturbation leads to a significant alteration in SLC35B3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 16114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CASC3 and then measure expression of GORAB. Does this perturbation cause a significant change in GORAB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CASC3 and then measure expression of GORAB. Does this perturbation cause a significant change in GORAB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 13281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP153 and examine the expression of SLC41A3. Does perturbing NUP153 lead to a significant change in SLC41A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP153 and examine the expression of SLC41A3. Does perturbing NUP153 lead to a significant change in SLC41A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 75875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSTF1 is associated with a significant change in DMKN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSTF1 is associated with a significant change in DMKN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 99170,"You are an expert in single-cell biology and functional genomics. In K562 cells, LSG1 is perturbed and the expression of NGRN is measured. Does this perturbation cause a significant change in NGRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LSG1 is perturbed and the expression of NGRN is measured. Does this perturbation cause a significant change in NGRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 62121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYC and examine the expression of GLCE. Does perturbing MYC lead to a significant change in GLCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYC and examine the expression of GLCE. Does perturbing MYC lead to a significant change in GLCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 29691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS30 and examine the expression of SNX24. Does perturbing MRPS30 lead to a significant change in SNX24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS30 and examine the expression of SNX24. Does perturbing MRPS30 lead to a significant change in SNX24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 48531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDK11A and examine the expression of PNRC1. Does perturbing CDK11A lead to a significant change in PNRC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDK11A and examine the expression of PNRC1. Does perturbing CDK11A lead to a significant change in PNRC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 122442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS25 is perturbed and NDUFAF8 expression is quantified. Does this perturbation result in a significant change in NDUFAF8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS25 is perturbed and NDUFAF8 expression is quantified. Does this perturbation result in a significant change in NDUFAF8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 83944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUP107 and then measure expression of SIL1. Does this perturbation cause a significant change in SIL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUP107 and then measure expression of SIL1. Does this perturbation cause a significant change in SIL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 81811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF5A and examine the expression of TNS3. Does perturbing EIF5A lead to a significant change in TNS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF5A and examine the expression of TNS3. Does perturbing EIF5A lead to a significant change in TNS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 66476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIPEP is perturbed and the expression of NMD3 is measured. Determine whether NMD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIPEP is perturbed and the expression of NMD3 is measured. Determine whether NMD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 10726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NSUN4 is perturbed and the expression of GAK is measured. Determine whether GAK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NSUN4 is perturbed and the expression of GAK is measured. Determine whether GAK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 41378,"You are a functional genomics specialist. In K562 cells, we perturb MED14 and monitor WIPF2 expression. Decide whether this perturbation leads to a significant alteration in WIPF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MED14 and monitor WIPF2 expression. Decide whether this perturbation leads to a significant alteration in WIPF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 75829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LRPPRC is perturbed and ACTL6A expression is measured. Determine whether ACTL6A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LRPPRC is perturbed and ACTL6A expression is measured. Determine whether ACTL6A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 120,"You are an expert in single-cell biology and functional genomics. In K562 cells, WBP1 is perturbed and the expression of HYOU1 is measured. Does this perturbation cause a significant change in HYOU1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, WBP1 is perturbed and the expression of HYOU1 is measured. Does this perturbation cause a significant change in HYOU1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 38675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF1 is associated with a significant change in DNAJB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF1 is associated with a significant change in DNAJB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 35668,"You are a functional genomics specialist. In K562 cells, we perturb HARS2 and monitor GADD45A expression. Decide whether this perturbation leads to a significant alteration in GADD45A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HARS2 and monitor GADD45A expression. Decide whether this perturbation leads to a significant alteration in GADD45A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 90383,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and TMEM63B expression is observed. Does this perturbation lead to a significant difference in TMEM63B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and TMEM63B expression is observed. Does this perturbation lead to a significant difference in TMEM63B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 16901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2I and examine the expression of CHID1. Does perturbing POLR2I lead to a significant change in CHID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2I and examine the expression of CHID1. Does perturbing POLR2I lead to a significant change in CHID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 82306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMG2 is perturbed and the expression of PARG is measured. Determine whether PARG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMG2 is perturbed and the expression of PARG is measured. Determine whether PARG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBTF is perturbed and SNHG30 expression is quantified. Does this perturbation result in a significant change in SNHG30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBTF is perturbed and SNHG30 expression is quantified. Does this perturbation result in a significant change in SNHG30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 54682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80D is perturbed and NAGK expression is quantified. Does this perturbation result in a significant change in NAGK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80D is perturbed and NAGK expression is quantified. Does this perturbation result in a significant change in NAGK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 41384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED14 and then measure expression of GABARAPL1. Does this perturbation cause a significant change in GABARAPL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED14 and then measure expression of GABARAPL1. Does this perturbation cause a significant change in GABARAPL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 97103,You are an expert in regulatory genomics. Consider data from K562 cells in which CINP is perturbed and LIG4 expression is observed. Does this perturbation lead to a significant difference in LIG4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CINP is perturbed and LIG4 expression is observed. Does this perturbation lead to a significant difference in LIG4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 10138,"You are a functional genomics specialist. In K562 cells, we perturb PPP2CB and monitor ATXN7 expression. Decide whether this perturbation leads to a significant alteration in ATXN7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PPP2CB and monitor ATXN7 expression. Decide whether this perturbation leads to a significant alteration in ATXN7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 79423,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF236 is perturbed and FBXW7 expression is observed. Does this perturbation lead to a significant difference in FBXW7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF236 is perturbed and FBXW7 expression is observed. Does this perturbation lead to a significant difference in FBXW7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 77815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUB1B is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUB1B is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 22748,"You are a functional genomics specialist. In K562 cells, we perturb SS18L2 and monitor ABHD10 expression. Decide whether this perturbation leads to a significant alteration in ABHD10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SS18L2 and monitor ABHD10 expression. Decide whether this perturbation leads to a significant alteration in ABHD10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 83371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT6 and examine the expression of GSTZ1. Does perturbing TRMT6 lead to a significant change in GSTZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT6 and examine the expression of GSTZ1. Does perturbing TRMT6 lead to a significant change in GSTZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 10344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VARS and then measure expression of KRCC1. Does this perturbation cause a significant change in KRCC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VARS and then measure expression of KRCC1. Does this perturbation cause a significant change in KRCC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 122077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF10, does the expression profile of KAT6B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF10, does the expression profile of KAT6B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 30408,"You are a functional genomics specialist. In K562 cells, we perturb KRT10 and monitor KPNA6 expression. Decide whether this perturbation leads to a significant alteration in KPNA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KRT10 and monitor KPNA6 expression. Decide whether this perturbation leads to a significant alteration in KPNA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 89342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS6 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS6 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 52720,"You are an expert in single-cell biology and functional genomics. In K562 cells, MCM3AP is perturbed and the expression of PLAAT4 is measured. Does this perturbation cause a significant change in PLAAT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MCM3AP is perturbed and the expression of PLAAT4 is measured. Does this perturbation cause a significant change in PLAAT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 102308,"You are a functional genomics specialist. In K562 cells, we perturb ZNF787 and monitor PRKX expression. Decide whether this perturbation leads to a significant alteration in PRKX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF787 and monitor PRKX expression. Decide whether this perturbation leads to a significant alteration in PRKX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2K, does the expression profile of APBB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2K, does the expression profile of APBB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 118260,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS8 is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS8 is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 60795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRELID1 is associated with a significant change in GABARAPL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRELID1 is associated with a significant change in GABARAPL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 72174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRNP27 and then measure expression of UBE2W. Does this perturbation cause a significant change in UBE2W expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRNP27 and then measure expression of UBE2W. Does this perturbation cause a significant change in UBE2W expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 67908,"You are a functional genomics specialist. In K562 cells, we perturb IWS1 and monitor INIP expression. Decide whether this perturbation leads to a significant alteration in INIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IWS1 and monitor INIP expression. Decide whether this perturbation leads to a significant alteration in INIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 88985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VMP1 is associated with a significant change in RAB11A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VMP1 is associated with a significant change in RAB11A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 12524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX17 and then measure expression of GRAMD1A. Does this perturbation cause a significant change in GRAMD1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX17 and then measure expression of GRAMD1A. Does this perturbation cause a significant change in GRAMD1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SERBP1 is perturbed and INTS3 expression is quantified. Does this perturbation result in a significant change in INTS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SERBP1 is perturbed and INTS3 expression is quantified. Does this perturbation result in a significant change in INTS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 65297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZFR, does the expression profile of PEX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZFR, does the expression profile of PEX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 38809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFA6 is perturbed and AOX1 expression is measured. Determine whether AOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFA6 is perturbed and AOX1 expression is measured. Determine whether AOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 26133,You are an expert in regulatory genomics. Consider data from K562 cells in which TXNL4B is perturbed and ETF1 expression is observed. Does this perturbation lead to a significant difference in ETF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TXNL4B is perturbed and ETF1 expression is observed. Does this perturbation lead to a significant difference in ETF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 87441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL10A and examine the expression of SMG7. Does perturbing RPL10A lead to a significant change in SMG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL10A and examine the expression of SMG7. Does perturbing RPL10A lead to a significant change in SMG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 90347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPLP2, does the expression profile of SIK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPLP2, does the expression profile of SIK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 102358,"You are a functional genomics specialist. In K562 cells, we perturb PSMC6 and monitor EZH1 expression. Decide whether this perturbation leads to a significant alteration in EZH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMC6 and monitor EZH1 expression. Decide whether this perturbation leads to a significant alteration in EZH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 63543,You are an expert in regulatory genomics. Consider data from K562 cells in which SMAGP is perturbed and CDCP1 expression is observed. Does this perturbation lead to a significant difference in CDCP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SMAGP is perturbed and CDCP1 expression is observed. Does this perturbation lead to a significant difference in CDCP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 69199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSAT1 is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSAT1 is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 64961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GON4L and examine the expression of ORMDL2. Does perturbing GON4L lead to a significant change in ORMDL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GON4L and examine the expression of ORMDL2. Does perturbing GON4L lead to a significant change in ORMDL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 30369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ICE1 is perturbed and HELQ expression is measured. Determine whether HELQ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ICE1 is perturbed and HELQ expression is measured. Determine whether HELQ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 51976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BRIP1 is perturbed and the expression of RHOA is measured. Determine whether RHOA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BRIP1 is perturbed and the expression of RHOA is measured. Determine whether RHOA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 51817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBMX2, does the expression profile of METTL16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBMX2, does the expression profile of METTL16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 78384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUB1 and then measure expression of SPIRE1. Does this perturbation cause a significant change in SPIRE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUB1 and then measure expression of SPIRE1. Does this perturbation cause a significant change in SPIRE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 58915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARPC1B is associated with a significant change in BCL2L13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARPC1B is associated with a significant change in BCL2L13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 82618,"You are a functional genomics specialist. In K562 cells, we perturb BNIP1 and monitor TSLP expression. Decide whether this perturbation leads to a significant alteration in TSLP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BNIP1 and monitor TSLP expression. Decide whether this perturbation leads to a significant alteration in TSLP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 104995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MT2A is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MT2A is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 90275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD17 is associated with a significant change in PTGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD17 is associated with a significant change in PTGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 119743,You are an expert in regulatory genomics. Consider data from K562 cells in which COPS4 is perturbed and RNF169 expression is observed. Does this perturbation lead to a significant difference in RNF169 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPS4 is perturbed and RNF169 expression is observed. Does this perturbation lead to a significant difference in RNF169 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 66338,"You are a functional genomics specialist. In K562 cells, we perturb ACTR1B and monitor LINC00511 expression. Decide whether this perturbation leads to a significant alteration in LINC00511 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ACTR1B and monitor LINC00511 expression. Decide whether this perturbation leads to a significant alteration in LINC00511 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 54485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GAPDH is associated with a significant change in MRTO4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GAPDH is associated with a significant change in MRTO4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 35284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSME1 and then measure expression of SYNJ2BP. Does this perturbation cause a significant change in SYNJ2BP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSME1 and then measure expression of SYNJ2BP. Does this perturbation cause a significant change in SYNJ2BP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 96670,"You are an expert in single-cell biology and functional genomics. In K562 cells, DSN1 is perturbed and the expression of CYFIP2 is measured. Does this perturbation cause a significant change in CYFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DSN1 is perturbed and the expression of CYFIP2 is measured. Does this perturbation cause a significant change in CYFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 72682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OPA1 is perturbed and SEM1 expression is quantified. Does this perturbation result in a significant change in SEM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OPA1 is perturbed and SEM1 expression is quantified. Does this perturbation result in a significant change in SEM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 94365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPF1 is associated with a significant change in NUDT9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPF1 is associated with a significant change in NUDT9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 50473,You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC3 is perturbed and RPS18 expression is observed. Does this perturbation lead to a significant difference in RPS18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC3 is perturbed and RPS18 expression is observed. Does this perturbation lead to a significant difference in RPS18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 32905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCKAP1 is associated with a significant change in CCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCKAP1 is associated with a significant change in CCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 30567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTNNBL1, does the expression profile of HIST3H2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTNNBL1, does the expression profile of HIST3H2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 104462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX41 is perturbed and DCAF10 expression is quantified. Does this perturbation result in a significant change in DCAF10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX41 is perturbed and DCAF10 expression is quantified. Does this perturbation result in a significant change in DCAF10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 100922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RNF168 is perturbed and NOVA1 expression is quantified. Does this perturbation result in a significant change in NOVA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RNF168 is perturbed and NOVA1 expression is quantified. Does this perturbation result in a significant change in NOVA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 67754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VEZT and then measure expression of EFL1. Does this perturbation cause a significant change in EFL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VEZT and then measure expression of EFL1. Does this perturbation cause a significant change in EFL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 15590,"You are an expert in single-cell biology and functional genomics. In K562 cells, ADAM10 is perturbed and the expression of COG6 is measured. Does this perturbation cause a significant change in COG6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ADAM10 is perturbed and the expression of COG6 is measured. Does this perturbation cause a significant change in COG6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 17589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTK is perturbed and CHM expression is measured. Determine whether CHM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTK is perturbed and CHM expression is measured. Determine whether CHM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 38483,You are an expert in regulatory genomics. Consider data from K562 cells in which GSK3B is perturbed and UQCC1 expression is observed. Does this perturbation lead to a significant difference in UQCC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GSK3B is perturbed and UQCC1 expression is observed. Does this perturbation lead to a significant difference in UQCC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 67059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DYNLRB1 is perturbed and STAT2 expression is measured. Determine whether STAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DYNLRB1 is perturbed and STAT2 expression is measured. Determine whether STAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 91345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAFAH1B1 is associated with a significant change in GPNMB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAFAH1B1 is associated with a significant change in GPNMB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 80615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEM1 is associated with a significant change in HHIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEM1 is associated with a significant change in HHIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 31300,"You are an expert in single-cell biology and functional genomics. In K562 cells, RFT1 is perturbed and the expression of KANSL2 is measured. Does this perturbation cause a significant change in KANSL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RFT1 is perturbed and the expression of KANSL2 is measured. Does this perturbation cause a significant change in KANSL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 117700,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS12 is perturbed and the expression of ZNF574 is measured. Does this perturbation cause a significant change in ZNF574 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS12 is perturbed and the expression of ZNF574 is measured. Does this perturbation cause a significant change in ZNF574 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 29115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJA3 is associated with a significant change in RMI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJA3 is associated with a significant change in RMI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 37532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STRIP1 is perturbed and GSDMD expression is quantified. Does this perturbation result in a significant change in GSDMD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STRIP1 is perturbed and GSDMD expression is quantified. Does this perturbation result in a significant change in GSDMD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 26112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TXNL4B is perturbed and DNAJC8 expression is quantified. Does this perturbation result in a significant change in DNAJC8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TXNL4B is perturbed and DNAJC8 expression is quantified. Does this perturbation result in a significant change in DNAJC8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 114221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FASN and examine the expression of DMD. Does perturbing FASN lead to a significant change in DMD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FASN and examine the expression of DMD. Does perturbing FASN lead to a significant change in DMD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 35404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EPB41L2 and then measure expression of METTL16. Does this perturbation cause a significant change in METTL16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EPB41L2 and then measure expression of METTL16. Does this perturbation cause a significant change in METTL16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 101239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMC2 is perturbed and DMXL2 expression is measured. Determine whether DMXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMC2 is perturbed and DMXL2 expression is measured. Determine whether DMXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 44582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and C1orf50 expression is quantified. Does this perturbation result in a significant change in C1orf50 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and C1orf50 expression is quantified. Does this perturbation result in a significant change in C1orf50 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFS3 is perturbed and CLHC1 expression is quantified. Does this perturbation result in a significant change in CLHC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFS3 is perturbed and CLHC1 expression is quantified. Does this perturbation result in a significant change in CLHC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 61744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSA and then measure expression of SMURF2. Does this perturbation cause a significant change in SMURF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSA and then measure expression of SMURF2. Does this perturbation cause a significant change in SMURF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 18863,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF706 is perturbed and MOSPD2 expression is observed. Does this perturbation lead to a significant difference in MOSPD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF706 is perturbed and MOSPD2 expression is observed. Does this perturbation lead to a significant difference in MOSPD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 40742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPP1CA is perturbed and SUGCT expression is quantified. Does this perturbation result in a significant change in SUGCT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPP1CA is perturbed and SUGCT expression is quantified. Does this perturbation result in a significant change in SUGCT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 43136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS14 is perturbed and the expression of TRIM16L is measured. Determine whether TRIM16L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS14 is perturbed and the expression of TRIM16L is measured. Determine whether TRIM16L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 73507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WARS, does the expression profile of NNT-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WARS, does the expression profile of NNT-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 100415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EPRS is associated with a significant change in BTF3L4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EPRS is associated with a significant change in BTF3L4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 57110,"You are an expert in single-cell biology and functional genomics. In K562 cells, RBX1 is perturbed and the expression of DNAJB14 is measured. Does this perturbation cause a significant change in DNAJB14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RBX1 is perturbed and the expression of DNAJB14 is measured. Does this perturbation cause a significant change in DNAJB14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 115155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF7 is associated with a significant change in ABHD14A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF7 is associated with a significant change in ABHD14A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 93340,"You are an expert in single-cell biology and functional genomics. In K562 cells, H2AFX is perturbed and the expression of ROR1 is measured. Does this perturbation cause a significant change in ROR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, H2AFX is perturbed and the expression of ROR1 is measured. Does this perturbation cause a significant change in ROR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 77249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NRDE2 is perturbed and LRP11 expression is measured. Determine whether LRP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NRDE2 is perturbed and LRP11 expression is measured. Determine whether LRP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 60600,"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR1C is perturbed and the expression of SLC25A12 is measured. Does this perturbation cause a significant change in SLC25A12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR1C is perturbed and the expression of SLC25A12 is measured. Does this perturbation cause a significant change in SLC25A12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 100381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EPRS and examine the expression of SAT1. Does perturbing EPRS lead to a significant change in SAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EPRS and examine the expression of SAT1. Does perturbing EPRS lead to a significant change in SAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 104098,"You are a functional genomics specialist. In K562 cells, we perturb MZT1 and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MZT1 and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 110810,"You are an expert in single-cell biology and functional genomics. In K562 cells, RAC1 is perturbed and the expression of ATP6AP1 is measured. Does this perturbation cause a significant change in ATP6AP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RAC1 is perturbed and the expression of ATP6AP1 is measured. Does this perturbation cause a significant change in ATP6AP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 84689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KAT7 is perturbed and MOB1A expression is measured. Determine whether MOB1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KAT7 is perturbed and MOB1A expression is measured. Determine whether MOB1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 77151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LONP1 and examine the expression of MRPL10. Does perturbing LONP1 lead to a significant change in MRPL10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LONP1 and examine the expression of MRPL10. Does perturbing LONP1 lead to a significant change in MRPL10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 8951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EMC7 and examine the expression of TMA7. Does perturbing EMC7 lead to a significant change in TMA7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EMC7 and examine the expression of TMA7. Does perturbing EMC7 lead to a significant change in TMA7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 82410,"You are an expert in single-cell biology and functional genomics. In K562 cells, KANSL2 is perturbed and the expression of WDR13 is measured. Does this perturbation cause a significant change in WDR13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KANSL2 is perturbed and the expression of WDR13 is measured. Does this perturbation cause a significant change in WDR13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 108010,"You are an expert in single-cell biology and functional genomics. In K562 cells, CYFIP1 is perturbed and the expression of FBXO32 is measured. Does this perturbation cause a significant change in FBXO32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CYFIP1 is perturbed and the expression of FBXO32 is measured. Does this perturbation cause a significant change in FBXO32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 66694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK2 and then measure expression of SIRT2. Does this perturbation cause a significant change in SIRT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK2 and then measure expression of SIRT2. Does this perturbation cause a significant change in SIRT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 107603,You are an expert in regulatory genomics. Consider data from K562 cells in which SNRPD2 is perturbed and MDM4 expression is observed. Does this perturbation lead to a significant difference in MDM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SNRPD2 is perturbed and MDM4 expression is observed. Does this perturbation lead to a significant difference in MDM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ACTB and examine the expression of TPD52L1. Does perturbing ACTB lead to a significant change in TPD52L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ACTB and examine the expression of TPD52L1. Does perturbing ACTB lead to a significant change in TPD52L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 107969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, METAP1 is perturbed and TLE1 expression is measured. Determine whether TLE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, METAP1 is perturbed and TLE1 expression is measured. Determine whether TLE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 100658,"You are a functional genomics specialist. In K562 cells, we perturb DNMT1 and monitor ATP10D expression. Decide whether this perturbation leads to a significant alteration in ATP10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DNMT1 and monitor ATP10D expression. Decide whether this perturbation leads to a significant alteration in ATP10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 37627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RFC3, does the expression profile of NREP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RFC3, does the expression profile of NREP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 87826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCT7 is perturbed and the expression of ORC3 is measured. Determine whether ORC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCT7 is perturbed and the expression of ORC3 is measured. Determine whether ORC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COX5A is perturbed and WDR45 expression is quantified. Does this perturbation result in a significant change in WDR45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COX5A is perturbed and WDR45 expression is quantified. Does this perturbation result in a significant change in WDR45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3550,"You are an expert in single-cell biology and functional genomics. In K562 cells, KDM2A is perturbed and the expression of LAPTM4B is measured. Does this perturbation cause a significant change in LAPTM4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KDM2A is perturbed and the expression of LAPTM4B is measured. Does this perturbation cause a significant change in LAPTM4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 54574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR3H and then measure expression of PPP1R11. Does this perturbation cause a significant change in PPP1R11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR3H and then measure expression of PPP1R11. Does this perturbation cause a significant change in PPP1R11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 59466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PMPCB is perturbed and the expression of CPE is measured. Determine whether CPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PMPCB is perturbed and the expression of CPE is measured. Determine whether CPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 10634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COG2 and then measure expression of DDX6. Does this perturbation cause a significant change in DDX6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COG2 and then measure expression of DDX6. Does this perturbation cause a significant change in DDX6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 109488,"You are a functional genomics specialist. In K562 cells, we perturb ERH and monitor SNHG17 expression. Decide whether this perturbation leads to a significant alteration in SNHG17 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ERH and monitor SNHG17 expression. Decide whether this perturbation leads to a significant alteration in SNHG17 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 96221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL4 and examine the expression of ASH1L. Does perturbing RPL4 lead to a significant change in ASH1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL4 and examine the expression of ASH1L. Does perturbing RPL4 lead to a significant change in ASH1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DCAF6 and then measure expression of COA7. Does this perturbation cause a significant change in COA7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DCAF6 and then measure expression of COA7. Does this perturbation cause a significant change in COA7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 30698,"You are a functional genomics specialist. In K562 cells, we perturb STX18 and monitor NR1H2 expression. Decide whether this perturbation leads to a significant alteration in NR1H2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STX18 and monitor NR1H2 expression. Decide whether this perturbation leads to a significant alteration in NR1H2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 26232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TWNK is perturbed and MPST expression is quantified. Does this perturbation result in a significant change in MPST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TWNK is perturbed and MPST expression is quantified. Does this perturbation result in a significant change in MPST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 122620,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR55 is perturbed and the expression of XYLT1 is measured. Does this perturbation cause a significant change in XYLT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR55 is perturbed and the expression of XYLT1 is measured. Does this perturbation cause a significant change in XYLT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 109327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEPCE, does the expression profile of TRAK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEPCE, does the expression profile of TRAK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 59439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NSA2 is perturbed and CSNK2B expression is measured. Determine whether CSNK2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NSA2 is perturbed and CSNK2B expression is measured. Determine whether CSNK2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 46246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL15 is perturbed and the expression of BRAT1 is measured. Determine whether BRAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL15 is perturbed and the expression of BRAT1 is measured. Determine whether BRAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 34822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PCID2 is perturbed and DHRS7 expression is quantified. Does this perturbation result in a significant change in DHRS7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PCID2 is perturbed and DHRS7 expression is quantified. Does this perturbation result in a significant change in DHRS7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 92869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1A is perturbed and EPHX4 expression is measured. Determine whether EPHX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1A is perturbed and EPHX4 expression is measured. Determine whether EPHX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 87682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL44 is perturbed and CYB5A expression is quantified. Does this perturbation result in a significant change in CYB5A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL44 is perturbed and CYB5A expression is quantified. Does this perturbation result in a significant change in CYB5A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 111579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4A1 is perturbed and MLH3 expression is measured. Determine whether MLH3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4A1 is perturbed and MLH3 expression is measured. Determine whether MLH3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to H3F3A and then measure expression of NDUFA12. Does this perturbation cause a significant change in NDUFA12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to H3F3A and then measure expression of NDUFA12. Does this perturbation cause a significant change in NDUFA12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 17651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MCMBP and examine the expression of DHRS4. Does perturbing MCMBP lead to a significant change in DHRS4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MCMBP and examine the expression of DHRS4. Does perturbing MCMBP lead to a significant change in DHRS4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 65210,"You are an expert in single-cell biology and functional genomics. In K562 cells, CWC25 is perturbed and the expression of RND3 is measured. Does this perturbation cause a significant change in RND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CWC25 is perturbed and the expression of RND3 is measured. Does this perturbation cause a significant change in RND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 7106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSR1 is perturbed and the expression of PBX1 is measured. Determine whether PBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSR1 is perturbed and the expression of PBX1 is measured. Determine whether PBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 87410,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL10A is perturbed and the expression of ISG15 is measured. Does this perturbation cause a significant change in ISG15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL10A is perturbed and the expression of ISG15 is measured. Does this perturbation cause a significant change in ISG15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 36751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD11 and examine the expression of MIDN. Does perturbing ABHD11 lead to a significant change in MIDN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD11 and examine the expression of MIDN. Does perturbing ABHD11 lead to a significant change in MIDN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 27211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INO80C and examine the expression of COPE. Does perturbing INO80C lead to a significant change in COPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INO80C and examine the expression of COPE. Does perturbing INO80C lead to a significant change in COPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 62900,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCBP1 is perturbed and the expression of RANGRF is measured. Does this perturbation cause a significant change in RANGRF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCBP1 is perturbed and the expression of RANGRF is measured. Does this perturbation cause a significant change in RANGRF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 91782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CRKL is perturbed and MBOAT2 expression is quantified. Does this perturbation result in a significant change in MBOAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CRKL is perturbed and MBOAT2 expression is quantified. Does this perturbation result in a significant change in MBOAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 61066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, INO80E is perturbed and the expression of KDM4B is measured. Determine whether KDM4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, INO80E is perturbed and the expression of KDM4B is measured. Determine whether KDM4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 111201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR82 and examine the expression of APH1B. Does perturbing WDR82 lead to a significant change in APH1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR82 and examine the expression of APH1B. Does perturbing WDR82 lead to a significant change in APH1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 52922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HMGN2 is perturbed and AGAP3 expression is quantified. Does this perturbation result in a significant change in AGAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HMGN2 is perturbed and AGAP3 expression is quantified. Does this perturbation result in a significant change in AGAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 121711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRCA1 and examine the expression of AL627171.2. Does perturbing BRCA1 lead to a significant change in AL627171.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRCA1 and examine the expression of AL627171.2. Does perturbing BRCA1 lead to a significant change in AL627171.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 102643,You are an expert in regulatory genomics. Consider data from K562 cells in which KANSL1 is perturbed and SPTLC1 expression is observed. Does this perturbation lead to a significant difference in SPTLC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KANSL1 is perturbed and SPTLC1 expression is observed. Does this perturbation lead to a significant difference in SPTLC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 17610,"You are an expert in single-cell biology and functional genomics. In K562 cells, MCMBP is perturbed and the expression of TULP4 is measured. Does this perturbation cause a significant change in TULP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MCMBP is perturbed and the expression of TULP4 is measured. Does this perturbation cause a significant change in TULP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 84088,"You are a functional genomics specialist. In K562 cells, we perturb KAT5 and monitor SASH1 expression. Decide whether this perturbation leads to a significant alteration in SASH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KAT5 and monitor SASH1 expression. Decide whether this perturbation leads to a significant alteration in SASH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 108167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC86, does the expression profile of SIRT6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC86, does the expression profile of SIRT6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 32967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPE1, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPE1, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 16135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CASC3 is associated with a significant change in RARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CASC3 is associated with a significant change in RARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 46539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NELFCD is perturbed and CHST11 expression is measured. Determine whether CHST11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NELFCD is perturbed and CHST11 expression is measured. Determine whether CHST11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 41082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KDM1A is perturbed and MPHOSPH8 expression is quantified. Does this perturbation result in a significant change in MPHOSPH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KDM1A is perturbed and MPHOSPH8 expression is quantified. Does this perturbation result in a significant change in MPHOSPH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 71018,"You are a functional genomics specialist. In K562 cells, we perturb COX6C and monitor SPIDR expression. Decide whether this perturbation leads to a significant alteration in SPIDR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COX6C and monitor SPIDR expression. Decide whether this perturbation leads to a significant alteration in SPIDR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 21242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NKAPD1 is perturbed and TRIM26 expression is quantified. Does this perturbation result in a significant change in TRIM26 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NKAPD1 is perturbed and TRIM26 expression is quantified. Does this perturbation result in a significant change in TRIM26 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 16069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SF3B5 is perturbed and KRTCAP2 expression is measured. Determine whether KRTCAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SF3B5 is perturbed and KRTCAP2 expression is measured. Determine whether KRTCAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 81422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80B is perturbed and ABCA1 expression is quantified. Does this perturbation result in a significant change in ABCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80B is perturbed and ABCA1 expression is quantified. Does this perturbation result in a significant change in ABCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 26669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YEATS2 is perturbed and RASSF3 expression is measured. Determine whether RASSF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YEATS2 is perturbed and RASSF3 expression is measured. Determine whether RASSF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 102053,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and MTURN expression is observed. Does this perturbation lead to a significant difference in MTURN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and MTURN expression is observed. Does this perturbation lead to a significant difference in MTURN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 69739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EBNA1BP2 is perturbed and IFT43 expression is measured. Determine whether IFT43 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EBNA1BP2 is perturbed and IFT43 expression is measured. Determine whether IFT43 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 73952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCNB1 is perturbed and UQCC3 expression is quantified. Does this perturbation result in a significant change in UQCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCNB1 is perturbed and UQCC3 expression is quantified. Does this perturbation result in a significant change in UQCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 26061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HIPK1 and examine the expression of BEND7. Does perturbing HIPK1 lead to a significant change in BEND7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HIPK1 and examine the expression of BEND7. Does perturbing HIPK1 lead to a significant change in BEND7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 15586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ADAM10 is perturbed and the expression of AC127502.2 is measured. Determine whether AC127502.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ADAM10 is perturbed and the expression of AC127502.2 is measured. Determine whether AC127502.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 14543,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and OPA1 expression is observed. Does this perturbation lead to a significant difference in OPA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and OPA1 expression is observed. Does this perturbation lead to a significant difference in OPA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 49703,You are an expert in regulatory genomics. Consider data from K562 cells in which GUK1 is perturbed and TIMM10B expression is observed. Does this perturbation lead to a significant difference in TIMM10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GUK1 is perturbed and TIMM10B expression is observed. Does this perturbation lead to a significant difference in TIMM10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 87950,"You are an expert in single-cell biology and functional genomics. In K562 cells, AFG3L2 is perturbed and the expression of HMGCL is measured. Does this perturbation cause a significant change in HMGCL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AFG3L2 is perturbed and the expression of HMGCL is measured. Does this perturbation cause a significant change in HMGCL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 121654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR75 and then measure expression of ST6GALNAC6. Does this perturbation cause a significant change in ST6GALNAC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR75 and then measure expression of ST6GALNAC6. Does this perturbation cause a significant change in ST6GALNAC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 101877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of LAMA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of LAMA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 50170,"You are an expert in single-cell biology and functional genomics. In K562 cells, PNKP is perturbed and the expression of CAMLG is measured. Does this perturbation cause a significant change in CAMLG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PNKP is perturbed and the expression of CAMLG is measured. Does this perturbation cause a significant change in CAMLG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 60047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUF2, does the expression profile of TOR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUF2, does the expression profile of TOR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 44463,You are an expert in regulatory genomics. Consider data from K562 cells in which CCT4 is perturbed and IFT22 expression is observed. Does this perturbation lead to a significant difference in IFT22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CCT4 is perturbed and IFT22 expression is observed. Does this perturbation lead to a significant difference in IFT22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 118443,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1C1 is perturbed and PRKCI expression is observed. Does this perturbation lead to a significant difference in PRKCI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1C1 is perturbed and PRKCI expression is observed. Does this perturbation lead to a significant difference in PRKCI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 74819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and RRAS expression is measured. Determine whether RRAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and RRAS expression is measured. Determine whether RRAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 101131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLA1 and examine the expression of PDP2. Does perturbing POLA1 lead to a significant change in PDP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLA1 and examine the expression of PDP2. Does perturbing POLA1 lead to a significant change in PDP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 7750,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBE2M is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBE2M is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 64315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK1 is associated with a significant change in KCNQ1OT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK1 is associated with a significant change in KCNQ1OT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 78389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BUB1 is perturbed and SPIRE1 expression is measured. Determine whether SPIRE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BUB1 is perturbed and SPIRE1 expression is measured. Determine whether SPIRE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 20390,"You are an expert in single-cell biology and functional genomics. In K562 cells, THAP1 is perturbed and the expression of EHBP1L1 is measured. Does this perturbation cause a significant change in EHBP1L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, THAP1 is perturbed and the expression of EHBP1L1 is measured. Does this perturbation cause a significant change in EHBP1L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 73843,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC17 is perturbed and RSBN1L expression is observed. Does this perturbation lead to a significant difference in RSBN1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC17 is perturbed and RSBN1L expression is observed. Does this perturbation lead to a significant difference in RSBN1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 18865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF706 is associated with a significant change in MOSPD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF706 is associated with a significant change in MOSPD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 56805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS13 is associated with a significant change in GTF2H4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS13 is associated with a significant change in GTF2H4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 20257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS8, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS8, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 95580,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF2BP2 is perturbed and the expression of PSTK is measured. Does this perturbation cause a significant change in PSTK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF2BP2 is perturbed and the expression of PSTK is measured. Does this perturbation cause a significant change in PSTK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 115192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RRP1 is perturbed and ARF3 expression is quantified. Does this perturbation result in a significant change in ARF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RRP1 is perturbed and ARF3 expression is quantified. Does this perturbation result in a significant change in ARF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 61277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPUSD4, does the expression profile of ANGPT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPUSD4, does the expression profile of ANGPT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 77209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LONP1 is perturbed and CDC42SE2 expression is measured. Determine whether CDC42SE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LONP1 is perturbed and CDC42SE2 expression is measured. Determine whether CDC42SE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 10541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBMXL1 and examine the expression of DLG3. Does perturbing RBMXL1 lead to a significant change in DLG3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBMXL1 and examine the expression of DLG3. Does perturbing RBMXL1 lead to a significant change in DLG3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 56732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, REV3L is perturbed and SOX12 expression is quantified. Does this perturbation result in a significant change in SOX12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, REV3L is perturbed and SOX12 expression is quantified. Does this perturbation result in a significant change in SOX12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 52664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAXX and then measure expression of PLA2G12A. Does this perturbation cause a significant change in PLA2G12A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAXX and then measure expression of PLA2G12A. Does this perturbation cause a significant change in PLA2G12A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 99887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM39, does the expression profile of RETREG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM39, does the expression profile of RETREG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 51822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBMX2 is perturbed and AC037198.1 expression is quantified. Does this perturbation result in a significant change in AC037198.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBMX2 is perturbed and AC037198.1 expression is quantified. Does this perturbation result in a significant change in AC037198.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 74608,"You are a functional genomics specialist. In K562 cells, we perturb CYC1 and monitor ZDHHC3 expression. Decide whether this perturbation leads to a significant alteration in ZDHHC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CYC1 and monitor ZDHHC3 expression. Decide whether this perturbation leads to a significant alteration in ZDHHC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 84421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SFSWAP and examine the expression of NTN4. Does perturbing SFSWAP lead to a significant change in NTN4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SFSWAP and examine the expression of NTN4. Does perturbing SFSWAP lead to a significant change in NTN4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 86566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CENPE is perturbed and the expression of IFNGR1 is measured. Determine whether IFNGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CENPE is perturbed and the expression of IFNGR1 is measured. Determine whether IFNGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 82931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL18 and examine the expression of NNMT. Does perturbing RPL18 lead to a significant change in NNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL18 and examine the expression of NNMT. Does perturbing RPL18 lead to a significant change in NNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 81996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCNC is perturbed and the expression of ITFG2 is measured. Determine whether ITFG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCNC is perturbed and the expression of ITFG2 is measured. Determine whether ITFG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 121519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FIP1L1 is perturbed and SUMF1 expression is measured. Determine whether SUMF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FIP1L1 is perturbed and SUMF1 expression is measured. Determine whether SUMF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 93163,You are an expert in regulatory genomics. Consider data from K562 cells in which NIP7 is perturbed and TMED10 expression is observed. Does this perturbation lead to a significant difference in TMED10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NIP7 is perturbed and TMED10 expression is observed. Does this perturbation lead to a significant difference in TMED10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 53293,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1H is perturbed and BRMS1 expression is observed. Does this perturbation lead to a significant difference in BRMS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1H is perturbed and BRMS1 expression is observed. Does this perturbation lead to a significant difference in BRMS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 78365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUB1 is associated with a significant change in FBXO32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUB1 is associated with a significant change in FBXO32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 95400,"You are an expert in single-cell biology and functional genomics. In K562 cells, C1orf131 is perturbed and the expression of MYL9 is measured. Does this perturbation cause a significant change in MYL9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C1orf131 is perturbed and the expression of MYL9 is measured. Does this perturbation cause a significant change in MYL9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 91684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX16 and then measure expression of CBWD5. Does this perturbation cause a significant change in CBWD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX16 and then measure expression of CBWD5. Does this perturbation cause a significant change in CBWD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 119349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SDHC is perturbed and ARIH2 expression is measured. Determine whether ARIH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SDHC is perturbed and ARIH2 expression is measured. Determine whether ARIH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 39907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRMT5, does the expression profile of RGS12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRMT5, does the expression profile of RGS12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 100534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS33 and then measure expression of MRNIP. Does this perturbation cause a significant change in MRNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS33 and then measure expression of MRNIP. Does this perturbation cause a significant change in MRNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 76958,"You are a functional genomics specialist. In K562 cells, we perturb PPP4R2 and monitor ZNF433-AS1 expression. Decide whether this perturbation leads to a significant alteration in ZNF433-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PPP4R2 and monitor ZNF433-AS1 expression. Decide whether this perturbation leads to a significant alteration in ZNF433-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARDBP and examine the expression of LTBP3. Does perturbing TARDBP lead to a significant change in LTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARDBP and examine the expression of LTBP3. Does perturbing TARDBP lead to a significant change in LTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 35652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS2 is perturbed and HCG18 expression is quantified. Does this perturbation result in a significant change in HCG18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS2 is perturbed and HCG18 expression is quantified. Does this perturbation result in a significant change in HCG18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 121203,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP54 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP54 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 119464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOL12 and then measure expression of SH3BGRL. Does this perturbation cause a significant change in SH3BGRL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOL12 and then measure expression of SH3BGRL. Does this perturbation cause a significant change in SH3BGRL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 120672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CTR9 is perturbed and ABHD14A expression is quantified. Does this perturbation result in a significant change in ABHD14A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CTR9 is perturbed and ABHD14A expression is quantified. Does this perturbation result in a significant change in ABHD14A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 93939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRD8 is perturbed and THOC6 expression is measured. Determine whether THOC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRD8 is perturbed and THOC6 expression is measured. Determine whether THOC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 51602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TUBB is perturbed and VPS8 expression is quantified. Does this perturbation result in a significant change in VPS8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TUBB is perturbed and VPS8 expression is quantified. Does this perturbation result in a significant change in VPS8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 43511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JAZF1 and examine the expression of IFT74. Does perturbing JAZF1 lead to a significant change in IFT74 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JAZF1 and examine the expression of IFT74. Does perturbing JAZF1 lead to a significant change in IFT74 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 98570,"You are an expert in single-cell biology and functional genomics. In K562 cells, USP37 is perturbed and the expression of SMURF2 is measured. Does this perturbation cause a significant change in SMURF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, USP37 is perturbed and the expression of SMURF2 is measured. Does this perturbation cause a significant change in SMURF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 83652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP2A2 is perturbed and INSIG1 expression is quantified. Does this perturbation result in a significant change in INSIG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP2A2 is perturbed and INSIG1 expression is quantified. Does this perturbation result in a significant change in INSIG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 59909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC4 is perturbed and CKAP4 expression is measured. Determine whether CKAP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC4 is perturbed and CKAP4 expression is measured. Determine whether CKAP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 108858,"You are a functional genomics specialist. In K562 cells, we perturb BCLAF1 and monitor DHX29 expression. Decide whether this perturbation leads to a significant alteration in DHX29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BCLAF1 and monitor DHX29 expression. Decide whether this perturbation leads to a significant alteration in DHX29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 45153,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB17 is perturbed and PALMD expression is observed. Does this perturbation lead to a significant difference in PALMD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB17 is perturbed and PALMD expression is observed. Does this perturbation lead to a significant difference in PALMD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 107402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG13 is perturbed and DNAJB11 expression is quantified. Does this perturbation result in a significant change in DNAJB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG13 is perturbed and DNAJB11 expression is quantified. Does this perturbation result in a significant change in DNAJB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 22154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STXBP4 and then measure expression of KRIT1. Does this perturbation cause a significant change in KRIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STXBP4 and then measure expression of KRIT1. Does this perturbation cause a significant change in KRIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 113825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KXD1 is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KXD1 is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 18384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YRDC and then measure expression of MGLL. Does this perturbation cause a significant change in MGLL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YRDC and then measure expression of MGLL. Does this perturbation cause a significant change in MGLL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 100623,You are an expert in regulatory genomics. Consider data from K562 cells in which DNMT1 is perturbed and TMEM127 expression is observed. Does this perturbation lead to a significant difference in TMEM127 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DNMT1 is perturbed and TMEM127 expression is observed. Does this perturbation lead to a significant difference in TMEM127 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 112743,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1E1 is perturbed and SAT1 expression is observed. Does this perturbation lead to a significant difference in SAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1E1 is perturbed and SAT1 expression is observed. Does this perturbation lead to a significant difference in SAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 18238,"You are a functional genomics specialist. In K562 cells, we perturb MRPL20 and monitor PIP4K2B expression. Decide whether this perturbation leads to a significant alteration in PIP4K2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL20 and monitor PIP4K2B expression. Decide whether this perturbation leads to a significant alteration in PIP4K2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZMAT2 is perturbed and NEU1 expression is measured. Determine whether NEU1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZMAT2 is perturbed and NEU1 expression is measured. Determine whether NEU1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 48163,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC4 is perturbed and G0S2 expression is observed. Does this perturbation lead to a significant difference in G0S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC4 is perturbed and G0S2 expression is observed. Does this perturbation lead to a significant difference in G0S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 122526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1CB is perturbed and the expression of RASSF7 is measured. Determine whether RASSF7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1CB is perturbed and the expression of RASSF7 is measured. Determine whether RASSF7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 55080,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF4A is perturbed and the expression of MTURN is measured. Does this perturbation cause a significant change in MTURN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF4A is perturbed and the expression of MTURN is measured. Does this perturbation cause a significant change in MTURN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 18313,You are an expert in regulatory genomics. Consider data from K562 cells in which AP2M1 is perturbed and PPARD expression is observed. Does this perturbation lead to a significant difference in PPARD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AP2M1 is perturbed and PPARD expression is observed. Does this perturbation lead to a significant difference in PPARD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 38704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCAPD2 and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCAPD2 and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTB, does the expression profile of TPD52L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTB, does the expression profile of TPD52L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 100477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GFER, does the expression profile of MRAS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GFER, does the expression profile of MRAS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 54784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OGFOD1 and then measure expression of OTUD5. Does this perturbation cause a significant change in OTUD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OGFOD1 and then measure expression of OTUD5. Does this perturbation cause a significant change in OTUD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 62761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TPI1 and examine the expression of MORC3. Does perturbing TPI1 lead to a significant change in MORC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TPI1 and examine the expression of MORC3. Does perturbing TPI1 lead to a significant change in MORC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 42955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LTBP3 is associated with a significant change in FZD8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LTBP3 is associated with a significant change in FZD8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 18083,You are an expert in regulatory genomics. Consider data from K562 cells in which FAM207A is perturbed and CD58 expression is observed. Does this perturbation lead to a significant difference in CD58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FAM207A is perturbed and CD58 expression is observed. Does this perturbation lead to a significant difference in CD58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 99995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOC1 is associated with a significant change in POLR2M expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOC1 is associated with a significant change in POLR2M expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 109054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of YIPF4. Does this perturbation cause a significant change in YIPF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of YIPF4. Does this perturbation cause a significant change in YIPF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 26323,You are an expert in regulatory genomics. Consider data from K562 cells in which MMS19 is perturbed and FUNDC1 expression is observed. Does this perturbation lead to a significant difference in FUNDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MMS19 is perturbed and FUNDC1 expression is observed. Does this perturbation lead to a significant difference in FUNDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 103828,"You are a functional genomics specialist. In K562 cells, we perturb PNO1 and monitor GAS2L1 expression. Decide whether this perturbation leads to a significant alteration in GAS2L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PNO1 and monitor GAS2L1 expression. Decide whether this perturbation leads to a significant alteration in GAS2L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 50272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HUWE1 is perturbed and OPTN expression is quantified. Does this perturbation result in a significant change in OPTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HUWE1 is perturbed and OPTN expression is quantified. Does this perturbation result in a significant change in OPTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 15589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ADAM10 is perturbed and AC127502.2 expression is measured. Determine whether AC127502.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ADAM10 is perturbed and AC127502.2 expression is measured. Determine whether AC127502.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 74602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CYC1 is perturbed and ZDHHC3 expression is quantified. Does this perturbation result in a significant change in ZDHHC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CYC1 is perturbed and ZDHHC3 expression is quantified. Does this perturbation result in a significant change in ZDHHC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 77474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP9 and then measure expression of FLYWCH1. Does this perturbation cause a significant change in FLYWCH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP9 and then measure expression of FLYWCH1. Does this perturbation cause a significant change in FLYWCH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 88964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA8 and then measure expression of CNN2. Does this perturbation cause a significant change in CNN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA8 and then measure expression of CNN2. Does this perturbation cause a significant change in CNN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 119245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COQ4 is associated with a significant change in MTA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COQ4 is associated with a significant change in MTA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 60820,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRELID1 is perturbed and the expression of TPRA1 is measured. Does this perturbation cause a significant change in TPRA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRELID1 is perturbed and the expression of TPRA1 is measured. Does this perturbation cause a significant change in TPRA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 25628,"You are a functional genomics specialist. In K562 cells, we perturb NEDD1 and monitor LINC00467 expression. Decide whether this perturbation leads to a significant alteration in LINC00467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NEDD1 and monitor LINC00467 expression. Decide whether this perturbation leads to a significant alteration in LINC00467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5933,You are an expert in regulatory genomics. Consider data from K562 cells in which PNISR is perturbed and PRICKLE2 expression is observed. Does this perturbation lead to a significant difference in PRICKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PNISR is perturbed and PRICKLE2 expression is observed. Does this perturbation lead to a significant difference in PRICKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 42333,You are an expert in regulatory genomics. Consider data from K562 cells in which TRMT10C is perturbed and SERTAD1 expression is observed. Does this perturbation lead to a significant difference in SERTAD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TRMT10C is perturbed and SERTAD1 expression is observed. Does this perturbation lead to a significant difference in SERTAD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 73087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SIN3A, does the expression profile of CLN8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SIN3A, does the expression profile of CLN8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 116752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TWISTNB is perturbed and DAP expression is quantified. Does this perturbation result in a significant change in DAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TWISTNB is perturbed and DAP expression is quantified. Does this perturbation result in a significant change in DAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 81549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS18 is perturbed and FAP expression is measured. Determine whether FAP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS18 is perturbed and FAP expression is measured. Determine whether FAP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 98412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PREB is perturbed and UBXN6 expression is quantified. Does this perturbation result in a significant change in UBXN6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PREB is perturbed and UBXN6 expression is quantified. Does this perturbation result in a significant change in UBXN6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 14682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLD1 is perturbed and NSUN5 expression is quantified. Does this perturbation result in a significant change in NSUN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLD1 is perturbed and NSUN5 expression is quantified. Does this perturbation result in a significant change in NSUN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 109906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS10 is perturbed and the expression of BAG4 is measured. Determine whether BAG4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS10 is perturbed and the expression of BAG4 is measured. Determine whether BAG4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 48401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR77 and examine the expression of CCNG1. Does perturbing WDR77 lead to a significant change in CCNG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR77 and examine the expression of CCNG1. Does perturbing WDR77 lead to a significant change in CCNG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 105955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AAR2 is associated with a significant change in CRIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AAR2 is associated with a significant change in CRIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 23373,You are an expert in regulatory genomics. Consider data from K562 cells in which CLTC is perturbed and GNPTAB expression is observed. Does this perturbation lead to a significant difference in GNPTAB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CLTC is perturbed and GNPTAB expression is observed. Does this perturbation lead to a significant difference in GNPTAB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 21616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSE1L is perturbed and the expression of TCEA2 is measured. Determine whether TCEA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSE1L is perturbed and the expression of TCEA2 is measured. Determine whether TCEA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 52362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO7 is perturbed and BDNF expression is quantified. Does this perturbation result in a significant change in BDNF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO7 is perturbed and BDNF expression is quantified. Does this perturbation result in a significant change in BDNF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 66214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of OGFRL1. Does this perturbation cause a significant change in OGFRL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of OGFRL1. Does this perturbation cause a significant change in OGFRL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 78810,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBA5 is perturbed and the expression of KPNA2 is measured. Does this perturbation cause a significant change in KPNA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBA5 is perturbed and the expression of KPNA2 is measured. Does this perturbation cause a significant change in KPNA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 38189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LAMTOR1 is perturbed and FNIP1 expression is measured. Determine whether FNIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LAMTOR1 is perturbed and FNIP1 expression is measured. Determine whether FNIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 34226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNOT3 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNOT3 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 68413,You are an expert in regulatory genomics. Consider data from K562 cells in which RBM28 is perturbed and CCDC9B expression is observed. Does this perturbation lead to a significant difference in CCDC9B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RBM28 is perturbed and CCDC9B expression is observed. Does this perturbation lead to a significant difference in CCDC9B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 28148,"You are a functional genomics specialist. In K562 cells, we perturb PFDN1 and monitor EVI5 expression. Decide whether this perturbation leads to a significant alteration in EVI5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PFDN1 and monitor EVI5 expression. Decide whether this perturbation leads to a significant alteration in EVI5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 22884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMA3 and then measure expression of RSF1. Does this perturbation cause a significant change in RSF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMA3 and then measure expression of RSF1. Does this perturbation cause a significant change in RSF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 84358,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor OGT expression. Decide whether this perturbation leads to a significant alteration in OGT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor OGT expression. Decide whether this perturbation leads to a significant alteration in OGT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 33860,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF7 is perturbed and the expression of NDUFB1 is measured. Does this perturbation cause a significant change in NDUFB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF7 is perturbed and the expression of NDUFB1 is measured. Does this perturbation cause a significant change in NDUFB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 78550,"You are an expert in single-cell biology and functional genomics. In K562 cells, TOPBP1 is perturbed and the expression of HCG18 is measured. Does this perturbation cause a significant change in HCG18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TOPBP1 is perturbed and the expression of HCG18 is measured. Does this perturbation cause a significant change in HCG18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 75373,You are an expert in regulatory genomics. Consider data from K562 cells in which ATF5 is perturbed and CAMK1D expression is observed. Does this perturbation lead to a significant difference in CAMK1D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATF5 is perturbed and CAMK1D expression is observed. Does this perturbation lead to a significant difference in CAMK1D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 91051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPZ and examine the expression of PYROXD2. Does perturbing CEBPZ lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPZ and examine the expression of PYROXD2. Does perturbing CEBPZ lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 19165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UPF2 is associated with a significant change in FAM214B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UPF2 is associated with a significant change in FAM214B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 36799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DBR1 is perturbed and TIMM10B expression is measured. Determine whether TIMM10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DBR1 is perturbed and TIMM10B expression is measured. Determine whether TIMM10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 41667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNASEH2C, does the expression profile of NAA16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNASEH2C, does the expression profile of NAA16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 69938,"You are a functional genomics specialist. In K562 cells, we perturb SNRPD1 and monitor SPPL3 expression. Decide whether this perturbation leads to a significant alteration in SPPL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SNRPD1 and monitor SPPL3 expression. Decide whether this perturbation leads to a significant alteration in SPPL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 53496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMB1 is perturbed and the expression of PITHD1 is measured. Determine whether PITHD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMB1 is perturbed and the expression of PITHD1 is measured. Determine whether PITHD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 49656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GUK1 is perturbed and the expression of UBL7 is measured. Determine whether UBL7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GUK1 is perturbed and the expression of UBL7 is measured. Determine whether UBL7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 59449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NSA2 is perturbed and HABP4 expression is measured. Determine whether HABP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NSA2 is perturbed and HABP4 expression is measured. Determine whether HABP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 33897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFAF7, does the expression profile of POLD4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFAF7, does the expression profile of POLD4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 25579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UCHL5 is perturbed and PICALM expression is measured. Determine whether PICALM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UCHL5 is perturbed and PICALM expression is measured. Determine whether PICALM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 110720,"You are an expert in single-cell biology and functional genomics. In K562 cells, GTF2H1 is perturbed and the expression of RPS28 is measured. Does this perturbation cause a significant change in RPS28 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GTF2H1 is perturbed and the expression of RPS28 is measured. Does this perturbation cause a significant change in RPS28 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 95278,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor TIMM22 expression. Decide whether this perturbation leads to a significant alteration in TIMM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor TIMM22 expression. Decide whether this perturbation leads to a significant alteration in TIMM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 61002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR5 is perturbed and CXorf40B expression is quantified. Does this perturbation result in a significant change in CXorf40B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR5 is perturbed and CXorf40B expression is quantified. Does this perturbation result in a significant change in CXorf40B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 58458,"You are a functional genomics specialist. In K562 cells, we perturb TOMM40 and monitor LPIN2 expression. Decide whether this perturbation leads to a significant alteration in LPIN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TOMM40 and monitor LPIN2 expression. Decide whether this perturbation leads to a significant alteration in LPIN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 72190,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRNP27 is perturbed and the expression of RSRP1 is measured. Does this perturbation cause a significant change in RSRP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRNP27 is perturbed and the expression of RSRP1 is measured. Does this perturbation cause a significant change in RSRP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SART1 and then measure expression of ARNT. Does this perturbation cause a significant change in ARNT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SART1 and then measure expression of ARNT. Does this perturbation cause a significant change in ARNT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 61991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2H4 and examine the expression of TGFBR2. Does perturbing GTF2H4 lead to a significant change in TGFBR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2H4 and examine the expression of TGFBR2. Does perturbing GTF2H4 lead to a significant change in TGFBR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 13570,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS21 is perturbed and the expression of PPP2R3A is measured. Does this perturbation cause a significant change in PPP2R3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS21 is perturbed and the expression of PPP2R3A is measured. Does this perturbation cause a significant change in PPP2R3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 8403,You are an expert in regulatory genomics. Consider data from K562 cells in which PGD is perturbed and PSMD6 expression is observed. Does this perturbation lead to a significant difference in PSMD6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PGD is perturbed and PSMD6 expression is observed. Does this perturbation lead to a significant difference in PSMD6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 96730,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD1 is perturbed and the expression of PLK3 is measured. Does this perturbation cause a significant change in PLK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD1 is perturbed and the expression of PLK3 is measured. Does this perturbation cause a significant change in PLK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 38860,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNUPN is perturbed and the expression of RDH11 is measured. Does this perturbation cause a significant change in RDH11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNUPN is perturbed and the expression of RDH11 is measured. Does this perturbation cause a significant change in RDH11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GFOD2 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GFOD2 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 10211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IMPDH2 and examine the expression of ARID2. Does perturbing IMPDH2 lead to a significant change in ARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IMPDH2 and examine the expression of ARID2. Does perturbing IMPDH2 lead to a significant change in ARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 25988,"You are a functional genomics specialist. In K562 cells, we perturb PRPF31 and monitor POLR2C expression. Decide whether this perturbation leads to a significant alteration in POLR2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRPF31 and monitor POLR2C expression. Decide whether this perturbation leads to a significant alteration in POLR2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 116678,"You are a functional genomics specialist. In K562 cells, we perturb POT1 and monitor TEX9 expression. Decide whether this perturbation leads to a significant alteration in TEX9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb POT1 and monitor TEX9 expression. Decide whether this perturbation leads to a significant alteration in TEX9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 75951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ENY2 and examine the expression of DCP2. Does perturbing ENY2 lead to a significant change in DCP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ENY2 and examine the expression of DCP2. Does perturbing ENY2 lead to a significant change in DCP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 53415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL15 is associated with a significant change in PAM16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL15 is associated with a significant change in PAM16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 9385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3L is associated with a significant change in TMEM115 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3L is associated with a significant change in TMEM115 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 49808,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor PLXNA2 expression. Decide whether this perturbation leads to a significant alteration in PLXNA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor PLXNA2 expression. Decide whether this perturbation leads to a significant alteration in PLXNA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 75203,You are an expert in regulatory genomics. Consider data from K562 cells in which FTSJ3 is perturbed and ZNF587 expression is observed. Does this perturbation lead to a significant difference in ZNF587 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FTSJ3 is perturbed and ZNF587 expression is observed. Does this perturbation lead to a significant difference in ZNF587 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 7729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2M is perturbed and CENPL expression is measured. Determine whether CENPL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2M is perturbed and CENPL expression is measured. Determine whether CENPL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 76248,"You are a functional genomics specialist. In K562 cells, we perturb HDAC3 and monitor FAM171A1 expression. Decide whether this perturbation leads to a significant alteration in FAM171A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HDAC3 and monitor FAM171A1 expression. Decide whether this perturbation leads to a significant alteration in FAM171A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 89552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PAM16 is perturbed and LNPEP expression is quantified. Does this perturbation result in a significant change in LNPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PAM16 is perturbed and LNPEP expression is quantified. Does this perturbation result in a significant change in LNPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 60336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD8 is perturbed and the expression of ZNF407 is measured. Determine whether ZNF407 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD8 is perturbed and the expression of ZNF407 is measured. Determine whether ZNF407 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 113705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2G is associated with a significant change in SCNM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2G is associated with a significant change in SCNM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 108900,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEN1 is perturbed and the expression of KCNN4 is measured. Does this perturbation cause a significant change in KCNN4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEN1 is perturbed and the expression of KCNN4 is measured. Does this perturbation cause a significant change in KCNN4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 13033,You are an expert in regulatory genomics. Consider data from K562 cells in which NAA38 is perturbed and NECTIN3 expression is observed. Does this perturbation lead to a significant difference in NECTIN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NAA38 is perturbed and NECTIN3 expression is observed. Does this perturbation lead to a significant difference in NECTIN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 65368,"You are a functional genomics specialist. In K562 cells, we perturb MRPS10 and monitor UQCRB expression. Decide whether this perturbation leads to a significant alteration in UQCRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPS10 and monitor UQCRB expression. Decide whether this perturbation leads to a significant alteration in UQCRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 97774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP14 and then measure expression of CNOT6L. Does this perturbation cause a significant change in CNOT6L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP14 and then measure expression of CNOT6L. Does this perturbation cause a significant change in CNOT6L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 21738,"You are a functional genomics specialist. In K562 cells, we perturb MMGT1 and monitor MTX3 expression. Decide whether this perturbation leads to a significant alteration in MTX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MMGT1 and monitor MTX3 expression. Decide whether this perturbation leads to a significant alteration in MTX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COX10 is perturbed and CEP55 expression is measured. Determine whether CEP55 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COX10 is perturbed and CEP55 expression is measured. Determine whether CEP55 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 88427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1333,You are an expert in regulatory genomics. Consider data from K562 cells in which NOLC1 is perturbed and PIK3R1 expression is observed. Does this perturbation lead to a significant difference in PIK3R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NOLC1 is perturbed and PIK3R1 expression is observed. Does this perturbation lead to a significant difference in PIK3R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 107528,"You are a functional genomics specialist. In K562 cells, we perturb ATP6V0D1 and monitor LIPA expression. Decide whether this perturbation leads to a significant alteration in LIPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATP6V0D1 and monitor LIPA expression. Decide whether this perturbation leads to a significant alteration in LIPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 18798,"You are a functional genomics specialist. In K562 cells, we perturb WAC and monitor ABL1 expression. Decide whether this perturbation leads to a significant alteration in ABL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb WAC and monitor ABL1 expression. Decide whether this perturbation leads to a significant alteration in ABL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 76982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LRP5 is perturbed and FAM214B expression is quantified. Does this perturbation result in a significant change in FAM214B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LRP5 is perturbed and FAM214B expression is quantified. Does this perturbation result in a significant change in FAM214B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDC6 is perturbed and the expression of OPTN is measured. Determine whether OPTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDC6 is perturbed and the expression of OPTN is measured. Determine whether OPTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 71166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABHD17A is perturbed and the expression of TUBGCP4 is measured. Determine whether TUBGCP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABHD17A is perturbed and the expression of TUBGCP4 is measured. Determine whether TUBGCP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 104661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOSC2 and examine the expression of ZNF197. Does perturbing EXOSC2 lead to a significant change in ZNF197 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOSC2 and examine the expression of ZNF197. Does perturbing EXOSC2 lead to a significant change in ZNF197 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 24555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPL is associated with a significant change in PDP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPL is associated with a significant change in PDP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 67758,"You are a functional genomics specialist. In K562 cells, we perturb VEZT and monitor EFL1 expression. Decide whether this perturbation leads to a significant alteration in EFL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb VEZT and monitor EFL1 expression. Decide whether this perturbation leads to a significant alteration in EFL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 67614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CXXC1 and then measure expression of RRP12. Does this perturbation cause a significant change in RRP12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CXXC1 and then measure expression of RRP12. Does this perturbation cause a significant change in RRP12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 22411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HLA-C and examine the expression of SIPA1L1. Does perturbing HLA-C lead to a significant change in SIPA1L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HLA-C and examine the expression of SIPA1L1. Does perturbing HLA-C lead to a significant change in SIPA1L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 119801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMB7 and examine the expression of RSF1. Does perturbing PSMB7 lead to a significant change in RSF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMB7 and examine the expression of RSF1. Does perturbing PSMB7 lead to a significant change in RSF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 54508,"You are a functional genomics specialist. In K562 cells, we perturb GAPDH and monitor SMIM10L1 expression. Decide whether this perturbation leads to a significant alteration in SMIM10L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GAPDH and monitor SMIM10L1 expression. Decide whether this perturbation leads to a significant alteration in SMIM10L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 18346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC1A is perturbed and the expression of CLIP3 is measured. Determine whether CLIP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC1A is perturbed and the expression of CLIP3 is measured. Determine whether CLIP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 98358,"You are a functional genomics specialist. In K562 cells, we perturb EXOSC3 and monitor MBD5 expression. Decide whether this perturbation leads to a significant alteration in MBD5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EXOSC3 and monitor MBD5 expression. Decide whether this perturbation leads to a significant alteration in MBD5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 56579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC10 is perturbed and STXBP1 expression is measured. Determine whether STXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC10 is perturbed and STXBP1 expression is measured. Determine whether STXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 97390,"You are an expert in single-cell biology and functional genomics. In K562 cells, THRAP3 is perturbed and the expression of GPAT3 is measured. Does this perturbation cause a significant change in GPAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, THRAP3 is perturbed and the expression of GPAT3 is measured. Does this perturbation cause a significant change in GPAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 108207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PIK3R4, does the expression profile of FAM149B1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PIK3R4, does the expression profile of FAM149B1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 53663,You are an expert in regulatory genomics. Consider data from K562 cells in which MYSM1 is perturbed and DDOST expression is observed. Does this perturbation lead to a significant difference in DDOST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MYSM1 is perturbed and DDOST expression is observed. Does this perturbation lead to a significant difference in DDOST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 40183,You are an expert in regulatory genomics. Consider data from K562 cells in which TCERG1 is perturbed and YIPF4 expression is observed. Does this perturbation lead to a significant difference in YIPF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TCERG1 is perturbed and YIPF4 expression is observed. Does this perturbation lead to a significant difference in YIPF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 107435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ALG13 is associated with a significant change in NIPA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ALG13 is associated with a significant change in NIPA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 64132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPP14 is perturbed and PLCB4 expression is quantified. Does this perturbation result in a significant change in PLCB4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPP14 is perturbed and PLCB4 expression is quantified. Does this perturbation result in a significant change in PLCB4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 106919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS is perturbed and CAMLG expression is measured. Determine whether CAMLG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS is perturbed and CAMLG expression is measured. Determine whether CAMLG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 33414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPS2 and then measure expression of AC027031.2. Does this perturbation cause a significant change in AC027031.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPS2 and then measure expression of AC027031.2. Does this perturbation cause a significant change in AC027031.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 89066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPS5 is perturbed and the expression of ATP2C1 is measured. Determine whether ATP2C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPS5 is perturbed and the expression of ATP2C1 is measured. Determine whether ATP2C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 8297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FASTKD5, does the expression profile of SSBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FASTKD5, does the expression profile of SSBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 24220,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPAP2 is perturbed and the expression of LTBR is measured. Does this perturbation cause a significant change in LTBR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RPAP2 is perturbed and the expression of LTBR is measured. Does this perturbation cause a significant change in LTBR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 33022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPIL1 is perturbed and KMT2B expression is quantified. Does this perturbation result in a significant change in KMT2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPIL1 is perturbed and KMT2B expression is quantified. Does this perturbation result in a significant change in KMT2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 20615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGLN2 is associated with a significant change in MIR210HG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGLN2 is associated with a significant change in MIR210HG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 76828,"You are a functional genomics specialist. In K562 cells, we perturb ANAPC11 and monitor NFKBIB expression. Decide whether this perturbation leads to a significant alteration in NFKBIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ANAPC11 and monitor NFKBIB expression. Decide whether this perturbation leads to a significant alteration in NFKBIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 98462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DYNC1H1 is perturbed and MAST4 expression is quantified. Does this perturbation result in a significant change in MAST4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DYNC1H1 is perturbed and MAST4 expression is quantified. Does this perturbation result in a significant change in MAST4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 41628,"You are a functional genomics specialist. In K562 cells, we perturb RNASEH2C and monitor TUBA4A expression. Decide whether this perturbation leads to a significant alteration in TUBA4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RNASEH2C and monitor TUBA4A expression. Decide whether this perturbation leads to a significant alteration in TUBA4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 93913,You are an expert in regulatory genomics. Consider data from K562 cells in which BRD8 is perturbed and FBXO32 expression is observed. Does this perturbation lead to a significant difference in FBXO32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BRD8 is perturbed and FBXO32 expression is observed. Does this perturbation lead to a significant difference in FBXO32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 108892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEN1 is perturbed and CYP1B1 expression is quantified. Does this perturbation result in a significant change in CYP1B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEN1 is perturbed and CYP1B1 expression is quantified. Does this perturbation result in a significant change in CYP1B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 104909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEPHS2 is perturbed and DHDDS expression is measured. Determine whether DHDDS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEPHS2 is perturbed and DHDDS expression is measured. Determine whether DHDDS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 11514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of RNF5. Does this perturbation cause a significant change in RNF5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of RNF5. Does this perturbation cause a significant change in RNF5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 78153,You are an expert in regulatory genomics. Consider data from K562 cells in which NOC4L is perturbed and CELF1 expression is observed. Does this perturbation lead to a significant difference in CELF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NOC4L is perturbed and CELF1 expression is observed. Does this perturbation lead to a significant difference in CELF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 66789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UHRF1 is perturbed and ESCO1 expression is measured. Determine whether ESCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UHRF1 is perturbed and ESCO1 expression is measured. Determine whether ESCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 12746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCBP2 is perturbed and the expression of IL7R is measured. Determine whether IL7R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCBP2 is perturbed and the expression of IL7R is measured. Determine whether IL7R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 61395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in SEC24D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in SEC24D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 22621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL41 and examine the expression of ACO1. Does perturbing RPL41 lead to a significant change in ACO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL41 and examine the expression of ACO1. Does perturbing RPL41 lead to a significant change in ACO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 76290,"You are an expert in single-cell biology and functional genomics. In K562 cells, PIK3C3 is perturbed and the expression of DYNLRB1 is measured. Does this perturbation cause a significant change in DYNLRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PIK3C3 is perturbed and the expression of DYNLRB1 is measured. Does this perturbation cause a significant change in DYNLRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HUS1 is perturbed and FAM120A expression is measured. Determine whether FAM120A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HUS1 is perturbed and FAM120A expression is measured. Determine whether FAM120A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUVBL2 and then measure expression of COPE. Does this perturbation cause a significant change in COPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUVBL2 and then measure expression of COPE. Does this perturbation cause a significant change in COPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 96860,"You are an expert in single-cell biology and functional genomics. In K562 cells, DIS3 is perturbed and the expression of PSEN1 is measured. Does this perturbation cause a significant change in PSEN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DIS3 is perturbed and the expression of PSEN1 is measured. Does this perturbation cause a significant change in PSEN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 81967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNC, does the expression profile of DNAJC17 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNC, does the expression profile of DNAJC17 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 88245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ESYT1 is associated with a significant change in BLOC1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ESYT1 is associated with a significant change in BLOC1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 52248,"You are a functional genomics specialist. In K562 cells, we perturb PPP1R10 and monitor SMG1 expression. Decide whether this perturbation leads to a significant alteration in SMG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PPP1R10 and monitor SMG1 expression. Decide whether this perturbation leads to a significant alteration in SMG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 44228,"You are a functional genomics specialist. In K562 cells, we perturb INTS1 and monitor RASSF8 expression. Decide whether this perturbation leads to a significant alteration in RASSF8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb INTS1 and monitor RASSF8 expression. Decide whether this perturbation leads to a significant alteration in RASSF8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 61070,"You are an expert in single-cell biology and functional genomics. In K562 cells, CPSF6 is perturbed and the expression of NFAT5 is measured. Does this perturbation cause a significant change in NFAT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CPSF6 is perturbed and the expression of NFAT5 is measured. Does this perturbation cause a significant change in NFAT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 99390,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of RINT1 is measured. Does this perturbation cause a significant change in RINT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of RINT1 is measured. Does this perturbation cause a significant change in RINT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 72756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OXA1L is perturbed and the expression of SLC37A4 is measured. Determine whether SLC37A4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OXA1L is perturbed and the expression of SLC37A4 is measured. Determine whether SLC37A4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 57285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANAPC10 is associated with a significant change in TIMM8B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANAPC10 is associated with a significant change in TIMM8B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2K and examine the expression of VAMP2. Does perturbing POLR2K lead to a significant change in VAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2K and examine the expression of VAMP2. Does perturbing POLR2K lead to a significant change in VAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 81070,"You are an expert in single-cell biology and functional genomics. In K562 cells, TOR2A is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TOR2A is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 71246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NLE1 is perturbed and the expression of D2HGDH is measured. Determine whether D2HGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NLE1 is perturbed and the expression of D2HGDH is measured. Determine whether D2HGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 92283,You are an expert in regulatory genomics. Consider data from K562 cells in which CCT8 is perturbed and CACNA2D1 expression is observed. Does this perturbation lead to a significant difference in CACNA2D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CCT8 is perturbed and CACNA2D1 expression is observed. Does this perturbation lead to a significant difference in CACNA2D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 77089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHCHD2 is perturbed and UBE2F expression is measured. Determine whether UBE2F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHCHD2 is perturbed and UBE2F expression is measured. Determine whether UBE2F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 67447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MVD, does the expression profile of IFT88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MVD, does the expression profile of IFT88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 71438,"You are a functional genomics specialist. In K562 cells, we perturb DHX36 and monitor NELFB expression. Decide whether this perturbation leads to a significant alteration in NELFB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DHX36 and monitor NELFB expression. Decide whether this perturbation leads to a significant alteration in NELFB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 11626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NASP is perturbed and the expression of YPEL5 is measured. Determine whether YPEL5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NASP is perturbed and the expression of YPEL5 is measured. Determine whether YPEL5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 11324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTK2 and then measure expression of USE1. Does this perturbation cause a significant change in USE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTK2 and then measure expression of USE1. Does this perturbation cause a significant change in USE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 42981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTBP3 and examine the expression of SNHG19. Does perturbing LTBP3 lead to a significant change in SNHG19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTBP3 and examine the expression of SNHG19. Does perturbing LTBP3 lead to a significant change in SNHG19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 118936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of SMIM12 is measured. Determine whether SMIM12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of SMIM12 is measured. Determine whether SMIM12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 30938,"You are a functional genomics specialist. In K562 cells, we perturb PALB2 and monitor PLPPR2 expression. Decide whether this perturbation leads to a significant alteration in PLPPR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PALB2 and monitor PLPPR2 expression. Decide whether this perturbation leads to a significant alteration in PLPPR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 69783,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and NUCB2 expression is observed. Does this perturbation lead to a significant difference in NUCB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and NUCB2 expression is observed. Does this perturbation lead to a significant difference in NUCB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 26104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TXNL4B and then measure expression of FDXR. Does this perturbation cause a significant change in FDXR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TXNL4B and then measure expression of FDXR. Does this perturbation cause a significant change in FDXR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 65445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDRG1 is associated with a significant change in WHAMM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDRG1 is associated with a significant change in WHAMM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 24952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX19A is perturbed and BET1L expression is quantified. Does this perturbation result in a significant change in BET1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX19A is perturbed and BET1L expression is quantified. Does this perturbation result in a significant change in BET1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 70475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of H2AFZ is associated with a significant change in SCAF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of H2AFZ is associated with a significant change in SCAF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 52963,You are an expert in regulatory genomics. Consider data from K562 cells in which ARPC2 is perturbed and ITGA11 expression is observed. Does this perturbation lead to a significant difference in ITGA11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARPC2 is perturbed and ITGA11 expression is observed. Does this perturbation lead to a significant difference in ITGA11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 50330,"You are an expert in single-cell biology and functional genomics. In K562 cells, HIRA is perturbed and the expression of GABARAPL1 is measured. Does this perturbation cause a significant change in GABARAPL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HIRA is perturbed and the expression of GABARAPL1 is measured. Does this perturbation cause a significant change in GABARAPL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 93639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NMD3 is perturbed and TXNDC9 expression is measured. Determine whether TXNDC9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NMD3 is perturbed and TXNDC9 expression is measured. Determine whether TXNDC9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 82570,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS7 is perturbed and the expression of LGALS8 is measured. Does this perturbation cause a significant change in LGALS8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS7 is perturbed and the expression of LGALS8 is measured. Does this perturbation cause a significant change in LGALS8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 48958,"You are a functional genomics specialist. In K562 cells, we perturb ZWINT and monitor POMGNT1 expression. Decide whether this perturbation leads to a significant alteration in POMGNT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZWINT and monitor POMGNT1 expression. Decide whether this perturbation leads to a significant alteration in POMGNT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 84506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COA5 is perturbed and the expression of JUP is measured. Determine whether JUP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COA5 is perturbed and the expression of JUP is measured. Determine whether JUP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 104691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF23 and examine the expression of FAM234A. Does perturbing KIF23 lead to a significant change in FAM234A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF23 and examine the expression of FAM234A. Does perturbing KIF23 lead to a significant change in FAM234A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 96553,You are an expert in regulatory genomics. Consider data from K562 cells in which TBC1D1 is perturbed and CYB5R1 expression is observed. Does this perturbation lead to a significant difference in CYB5R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBC1D1 is perturbed and CYB5R1 expression is observed. Does this perturbation lead to a significant difference in CYB5R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 72626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS26 is perturbed and the expression of TUBA1B is measured. Determine whether TUBA1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS26 is perturbed and the expression of TUBA1B is measured. Determine whether TUBA1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 25413,You are an expert in regulatory genomics. Consider data from K562 cells in which SMC4 is perturbed and CHP1 expression is observed. Does this perturbation lead to a significant difference in CHP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SMC4 is perturbed and CHP1 expression is observed. Does this perturbation lead to a significant difference in CHP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 27225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP98 is associated with a significant change in SLC44A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP98 is associated with a significant change in SLC44A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 39892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBA3 is perturbed and GPATCH8 expression is quantified. Does this perturbation result in a significant change in GPATCH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBA3 is perturbed and GPATCH8 expression is quantified. Does this perturbation result in a significant change in GPATCH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 57457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUDS3, does the expression profile of ABI1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUDS3, does the expression profile of ABI1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 17709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRA1 is perturbed and GID4 expression is measured. Determine whether GID4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRA1 is perturbed and GID4 expression is measured. Determine whether GID4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 63006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NAA10 is perturbed and the expression of TMED7 is measured. Determine whether TMED7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NAA10 is perturbed and the expression of TMED7 is measured. Determine whether TMED7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 41542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELP5 is perturbed and RPL37A expression is quantified. Does this perturbation result in a significant change in RPL37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELP5 is perturbed and RPL37A expression is quantified. Does this perturbation result in a significant change in RPL37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 46789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPE is perturbed and STX5 expression is measured. Determine whether STX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPE is perturbed and STX5 expression is measured. Determine whether STX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 41826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FNBP4 is perturbed and the expression of ZNF395 is measured. Determine whether ZNF395 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FNBP4 is perturbed and the expression of ZNF395 is measured. Determine whether ZNF395 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 22860,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCR is perturbed and the expression of TIMM29 is measured. Does this perturbation cause a significant change in TIMM29 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCR is perturbed and the expression of TIMM29 is measured. Does this perturbation cause a significant change in TIMM29 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 109913,You are an expert in regulatory genomics. Consider data from K562 cells in which TRRAP is perturbed and LTBP3 expression is observed. Does this perturbation lead to a significant difference in LTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TRRAP is perturbed and LTBP3 expression is observed. Does this perturbation lead to a significant difference in LTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 95100,"You are an expert in single-cell biology and functional genomics. In K562 cells, SMC3 is perturbed and the expression of VAMP4 is measured. Does this perturbation cause a significant change in VAMP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SMC3 is perturbed and the expression of VAMP4 is measured. Does this perturbation cause a significant change in VAMP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 74405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERCC2 is associated with a significant change in COL4A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERCC2 is associated with a significant change in COL4A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 47240,"You are an expert in single-cell biology and functional genomics. In K562 cells, EFR3A is perturbed and the expression of MLST8 is measured. Does this perturbation cause a significant change in MLST8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EFR3A is perturbed and the expression of MLST8 is measured. Does this perturbation cause a significant change in MLST8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 40846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COQ5 is perturbed and the expression of ATG16L1 is measured. Determine whether ATG16L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COQ5 is perturbed and the expression of ATG16L1 is measured. Determine whether ATG16L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 115381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMA2 and examine the expression of KIAA1217. Does perturbing PSMA2 lead to a significant change in KIAA1217 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMA2 and examine the expression of KIAA1217. Does perturbing PSMA2 lead to a significant change in KIAA1217 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 102490,"You are an expert in single-cell biology and functional genomics. In K562 cells, EXOC5 is perturbed and the expression of BAZ2B is measured. Does this perturbation cause a significant change in BAZ2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EXOC5 is perturbed and the expression of BAZ2B is measured. Does this perturbation cause a significant change in BAZ2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 82226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPRD1B is perturbed and the expression of PEX13 is measured. Determine whether PEX13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPRD1B is perturbed and the expression of PEX13 is measured. Determine whether PEX13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 122571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR55 and examine the expression of RTL8C. Does perturbing WDR55 lead to a significant change in RTL8C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR55 and examine the expression of RTL8C. Does perturbing WDR55 lead to a significant change in RTL8C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 53886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NAA25 is perturbed and the expression of CCDC186 is measured. Determine whether CCDC186 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NAA25 is perturbed and the expression of CCDC186 is measured. Determine whether CCDC186 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 45937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NSMCE2, does the expression profile of MAGED2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NSMCE2, does the expression profile of MAGED2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 62318,"You are a functional genomics specialist. In K562 cells, we perturb POGZ and monitor CYSTM1 expression. Decide whether this perturbation leads to a significant alteration in CYSTM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb POGZ and monitor CYSTM1 expression. Decide whether this perturbation leads to a significant alteration in CYSTM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 61252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD4 is perturbed and TAZ expression is quantified. Does this perturbation result in a significant change in TAZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD4 is perturbed and TAZ expression is quantified. Does this perturbation result in a significant change in TAZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 71365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAK1IP1 is associated with a significant change in SMG9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAK1IP1 is associated with a significant change in SMG9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 122789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS28 is perturbed and RTN4 expression is measured. Determine whether RTN4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS28 is perturbed and RTN4 expression is measured. Determine whether RTN4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 75652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GABPA is perturbed and ZBTB11 expression is quantified. Does this perturbation result in a significant change in ZBTB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GABPA is perturbed and ZBTB11 expression is quantified. Does this perturbation result in a significant change in ZBTB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 78392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUB1 is perturbed and TOGARAM1 expression is quantified. Does this perturbation result in a significant change in TOGARAM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUB1 is perturbed and TOGARAM1 expression is quantified. Does this perturbation result in a significant change in TOGARAM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 71930,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHTF18 is perturbed and the expression of MSRB1 is measured. Does this perturbation cause a significant change in MSRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHTF18 is perturbed and the expression of MSRB1 is measured. Does this perturbation cause a significant change in MSRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 78244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARL4D and then measure expression of PGAM5. Does this perturbation cause a significant change in PGAM5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARL4D and then measure expression of PGAM5. Does this perturbation cause a significant change in PGAM5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 27227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP98, does the expression profile of SLC44A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP98, does the expression profile of SLC44A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 121353,You are an expert in regulatory genomics. Consider data from K562 cells in which DR1 is perturbed and FN1 expression is observed. Does this perturbation lead to a significant difference in FN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DR1 is perturbed and FN1 expression is observed. Does this perturbation lead to a significant difference in FN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 95024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of ZNF430. Does this perturbation cause a significant change in ZNF430 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of ZNF430. Does this perturbation cause a significant change in ZNF430 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 97750,"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP14 is perturbed and the expression of KDM4B is measured. Does this perturbation cause a significant change in KDM4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP14 is perturbed and the expression of KDM4B is measured. Does this perturbation cause a significant change in KDM4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 59390,"You are an expert in single-cell biology and functional genomics. In K562 cells, NSA2 is perturbed and the expression of SERPINB2 is measured. Does this perturbation cause a significant change in SERPINB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NSA2 is perturbed and the expression of SERPINB2 is measured. Does this perturbation cause a significant change in SERPINB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 11620,"You are an expert in single-cell biology and functional genomics. In K562 cells, NASP is perturbed and the expression of YPEL5 is measured. Does this perturbation cause a significant change in YPEL5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NASP is perturbed and the expression of YPEL5 is measured. Does this perturbation cause a significant change in YPEL5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFS5 is perturbed and the expression of ATP6V1A is measured. Determine whether ATP6V1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFS5 is perturbed and the expression of ATP6V1A is measured. Determine whether ATP6V1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 23076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHTOP is perturbed and the expression of ACYP1 is measured. Determine whether ACYP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHTOP is perturbed and the expression of ACYP1 is measured. Determine whether ACYP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 46768,"You are a functional genomics specialist. In K562 cells, we perturb DPH3 and monitor RP9 expression. Decide whether this perturbation leads to a significant alteration in RP9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DPH3 and monitor RP9 expression. Decide whether this perturbation leads to a significant alteration in RP9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 82232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPRD1B is perturbed and FBXW7 expression is quantified. Does this perturbation result in a significant change in FBXW7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPRD1B is perturbed and FBXW7 expression is quantified. Does this perturbation result in a significant change in FBXW7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 71950,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHTF18 is perturbed and the expression of NDST1 is measured. Does this perturbation cause a significant change in NDST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHTF18 is perturbed and the expression of NDST1 is measured. Does this perturbation cause a significant change in NDST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 25265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC16 is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC16 is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 38403,You are an expert in regulatory genomics. Consider data from K562 cells in which ATF4 is perturbed and KRI1 expression is observed. Does this perturbation lead to a significant difference in KRI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATF4 is perturbed and KRI1 expression is observed. Does this perturbation lead to a significant difference in KRI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 70090,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZCRB1 is perturbed and the expression of GREM1 is measured. Does this perturbation cause a significant change in GREM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZCRB1 is perturbed and the expression of GREM1 is measured. Does this perturbation cause a significant change in GREM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 84908,"You are a functional genomics specialist. In K562 cells, we perturb SNAPC2 and monitor C9orf85 expression. Decide whether this perturbation leads to a significant alteration in C9orf85 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SNAPC2 and monitor C9orf85 expression. Decide whether this perturbation leads to a significant alteration in C9orf85 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 60281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YY1 and examine the expression of MSRA. Does perturbing YY1 lead to a significant change in MSRA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YY1 and examine the expression of MSRA. Does perturbing YY1 lead to a significant change in MSRA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 13371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF3C1 and examine the expression of MOB2. Does perturbing GTF3C1 lead to a significant change in MOB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF3C1 and examine the expression of MOB2. Does perturbing GTF3C1 lead to a significant change in MOB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 58634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL6 and then measure expression of VOPP1. Does this perturbation cause a significant change in VOPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL6 and then measure expression of VOPP1. Does this perturbation cause a significant change in VOPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 55348,"You are a functional genomics specialist. In K562 cells, we perturb SMG8 and monitor CDS2 expression. Decide whether this perturbation leads to a significant alteration in CDS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SMG8 and monitor CDS2 expression. Decide whether this perturbation leads to a significant alteration in CDS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 77642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS21 is perturbed and FBXL15 expression is quantified. Does this perturbation result in a significant change in FBXL15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS21 is perturbed and FBXL15 expression is quantified. Does this perturbation result in a significant change in FBXL15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 33040,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPIL1 is perturbed and the expression of COMMD9 is measured. Does this perturbation cause a significant change in COMMD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPIL1 is perturbed and the expression of COMMD9 is measured. Does this perturbation cause a significant change in COMMD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 103052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDK12 is perturbed and AK2 expression is quantified. Does this perturbation result in a significant change in AK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDK12 is perturbed and AK2 expression is quantified. Does this perturbation result in a significant change in AK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 44483,You are an expert in regulatory genomics. Consider data from K562 cells in which CCT4 is perturbed and SGK1 expression is observed. Does this perturbation lead to a significant difference in SGK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CCT4 is perturbed and SGK1 expression is observed. Does this perturbation lead to a significant difference in SGK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 112045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SDHD is associated with a significant change in RAB27B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SDHD is associated with a significant change in RAB27B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 70630,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNIP1 is perturbed and the expression of MED10 is measured. Does this perturbation cause a significant change in MED10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNIP1 is perturbed and the expression of MED10 is measured. Does this perturbation cause a significant change in MED10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 19395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPW is associated with a significant change in FBXO32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPW is associated with a significant change in FBXO32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 93818,"You are a functional genomics specialist. In K562 cells, we perturb CTU2 and monitor SP2 expression. Decide whether this perturbation leads to a significant alteration in SP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CTU2 and monitor SP2 expression. Decide whether this perturbation leads to a significant alteration in SP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 73937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNB1, does the expression profile of ZNF576 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNB1, does the expression profile of ZNF576 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 70933,You are an expert in regulatory genomics. Consider data from K562 cells in which SDR39U1 is perturbed and GBE1 expression is observed. Does this perturbation lead to a significant difference in GBE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SDR39U1 is perturbed and GBE1 expression is observed. Does this perturbation lead to a significant difference in GBE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 102220,"You are an expert in single-cell biology and functional genomics. In K562 cells, LRR1 is perturbed and the expression of MIR31HG is measured. Does this perturbation cause a significant change in MIR31HG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LRR1 is perturbed and the expression of MIR31HG is measured. Does this perturbation cause a significant change in MIR31HG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 103814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PNO1 and then measure expression of ZFYVE21. Does this perturbation cause a significant change in ZFYVE21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PNO1 and then measure expression of ZFYVE21. Does this perturbation cause a significant change in ZFYVE21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 56574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC10 and then measure expression of STXBP1. Does this perturbation cause a significant change in STXBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC10 and then measure expression of STXBP1. Does this perturbation cause a significant change in STXBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 102304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF787 and then measure expression of PRKX. Does this perturbation cause a significant change in PRKX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF787 and then measure expression of PRKX. Does this perturbation cause a significant change in PRKX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 110060,"You are an expert in single-cell biology and functional genomics. In K562 cells, BUD13 is perturbed and the expression of DDB2 is measured. Does this perturbation cause a significant change in DDB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BUD13 is perturbed and the expression of DDB2 is measured. Does this perturbation cause a significant change in DDB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 77031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD2 and examine the expression of HIBADH. Does perturbing CHCHD2 lead to a significant change in HIBADH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD2 and examine the expression of HIBADH. Does perturbing CHCHD2 lead to a significant change in HIBADH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 58090,"You are an expert in single-cell biology and functional genomics. In K562 cells, SFPQ is perturbed and the expression of DMKN is measured. Does this perturbation cause a significant change in DMKN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SFPQ is perturbed and the expression of DMKN is measured. Does this perturbation cause a significant change in DMKN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 95697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAMM41, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAMM41, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3658,"You are a functional genomics specialist. In K562 cells, we perturb DTYMK and monitor LYSMD3 expression. Decide whether this perturbation leads to a significant alteration in LYSMD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DTYMK and monitor LYSMD3 expression. Decide whether this perturbation leads to a significant alteration in LYSMD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 77713,You are an expert in regulatory genomics. Consider data from K562 cells in which UBE2I is perturbed and ERV3-1 expression is observed. Does this perturbation lead to a significant difference in ERV3-1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBE2I is perturbed and ERV3-1 expression is observed. Does this perturbation lead to a significant difference in ERV3-1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 95071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX11 and examine the expression of ZNF668. Does perturbing DDX11 lead to a significant change in ZNF668 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX11 and examine the expression of ZNF668. Does perturbing DDX11 lead to a significant change in ZNF668 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 38502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GSK3B is perturbed and ARAF expression is quantified. Does this perturbation result in a significant change in ARAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GSK3B is perturbed and ARAF expression is quantified. Does this perturbation result in a significant change in ARAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 38348,"You are a functional genomics specialist. In K562 cells, we perturb TUBE1 and monitor TOLLIP expression. Decide whether this perturbation leads to a significant alteration in TOLLIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TUBE1 and monitor TOLLIP expression. Decide whether this perturbation leads to a significant alteration in TOLLIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 43087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YBX1, does the expression profile of XPO7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YBX1, does the expression profile of XPO7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 106487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2A, does the expression profile of USP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2A, does the expression profile of USP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 91984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRBD1 and then measure expression of KIAA0100. Does this perturbation cause a significant change in KIAA0100 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRBD1 and then measure expression of KIAA0100. Does this perturbation cause a significant change in KIAA0100 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 17954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB2 and then measure expression of STIP1. Does this perturbation cause a significant change in STIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB2 and then measure expression of STIP1. Does this perturbation cause a significant change in STIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 99300,"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of MTHFS is measured. Does this perturbation cause a significant change in MTHFS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of MTHFS is measured. Does this perturbation cause a significant change in MTHFS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 97132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP3 is perturbed and CLN8 expression is quantified. Does this perturbation result in a significant change in CLN8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP3 is perturbed and CLN8 expression is quantified. Does this perturbation result in a significant change in CLN8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM242 and examine the expression of DDIT4. Does perturbing TMEM242 lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM242 and examine the expression of DDIT4. Does perturbing TMEM242 lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 122840,"You are an expert in single-cell biology and functional genomics. In K562 cells, BARD1 is perturbed and the expression of SPSB2 is measured. Does this perturbation cause a significant change in SPSB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BARD1 is perturbed and the expression of SPSB2 is measured. Does this perturbation cause a significant change in SPSB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 85856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBA1C is perturbed and the expression of KMT5B is measured. Determine whether KMT5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBA1C is perturbed and the expression of KMT5B is measured. Determine whether KMT5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 7016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GFOD2 is perturbed and the expression of TRAK1 is measured. Determine whether TRAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GFOD2 is perturbed and the expression of TRAK1 is measured. Determine whether TRAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 115904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SDE2 and then measure expression of ZMAT2. Does this perturbation cause a significant change in ZMAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SDE2 and then measure expression of ZMAT2. Does this perturbation cause a significant change in ZMAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 8055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HMGA1 is associated with a significant change in CHD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HMGA1 is associated with a significant change in CHD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 58560,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPA is perturbed and the expression of ZNF672 is measured. Does this perturbation cause a significant change in ZNF672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPA is perturbed and the expression of ZNF672 is measured. Does this perturbation cause a significant change in ZNF672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 72784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2R1A and then measure expression of AC092807.3. Does this perturbation cause a significant change in AC092807.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2R1A and then measure expression of AC092807.3. Does this perturbation cause a significant change in AC092807.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 99031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PHF5A and examine the expression of SRSF10. Does perturbing PHF5A lead to a significant change in SRSF10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PHF5A and examine the expression of SRSF10. Does perturbing PHF5A lead to a significant change in SRSF10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 71201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD17A and examine the expression of DTNBP1. Does perturbing ABHD17A lead to a significant change in DTNBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD17A and examine the expression of DTNBP1. Does perturbing ABHD17A lead to a significant change in DTNBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 72877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ILF3, does the expression profile of RITA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ILF3, does the expression profile of RITA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 108886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCLAF1 is perturbed and the expression of ZDHHC16 is measured. Determine whether ZDHHC16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCLAF1 is perturbed and the expression of ZDHHC16 is measured. Determine whether ZDHHC16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 72223,You are an expert in regulatory genomics. Consider data from K562 cells in which SNRNP27 is perturbed and PRDX2 expression is observed. Does this perturbation lead to a significant difference in PRDX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SNRNP27 is perturbed and PRDX2 expression is observed. Does this perturbation lead to a significant difference in PRDX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 54742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPH6 is perturbed and PIP4P1 expression is quantified. Does this perturbation result in a significant change in PIP4P1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPH6 is perturbed and PIP4P1 expression is quantified. Does this perturbation result in a significant change in PIP4P1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 85381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASF1B and examine the expression of PDPR. Does perturbing ASF1B lead to a significant change in PDPR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASF1B and examine the expression of PDPR. Does perturbing ASF1B lead to a significant change in PDPR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 11408,"You are a functional genomics specialist. In K562 cells, we perturb RSRC2 and monitor PAK4 expression. Decide whether this perturbation leads to a significant alteration in PAK4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RSRC2 and monitor PAK4 expression. Decide whether this perturbation leads to a significant alteration in PAK4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 81476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MMS22L is perturbed and the expression of PLPPR2 is measured. Determine whether PLPPR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MMS22L is perturbed and the expression of PLPPR2 is measured. Determine whether PLPPR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 33921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD1 and examine the expression of EXOSC10. Does perturbing CHCHD1 lead to a significant change in EXOSC10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD1 and examine the expression of EXOSC10. Does perturbing CHCHD1 lead to a significant change in EXOSC10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 28353,You are an expert in regulatory genomics. Consider data from K562 cells in which RNF113A is perturbed and SLU7 expression is observed. Does this perturbation lead to a significant difference in SLU7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RNF113A is perturbed and SLU7 expression is observed. Does this perturbation lead to a significant difference in SLU7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 66599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL23 is perturbed and FAM171B expression is measured. Determine whether FAM171B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL23 is perturbed and FAM171B expression is measured. Determine whether FAM171B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 99647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPRC1, does the expression profile of SPP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPRC1, does the expression profile of SPP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 65924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFB6 and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFB6 and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 38713,You are an expert in regulatory genomics. Consider data from K562 cells in which NCAPD2 is perturbed and DYSF expression is observed. Does this perturbation lead to a significant difference in DYSF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NCAPD2 is perturbed and DYSF expression is observed. Does this perturbation lead to a significant difference in DYSF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 79871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC4 and examine the expression of NORAD. Does perturbing TRAPPC4 lead to a significant change in NORAD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC4 and examine the expression of NORAD. Does perturbing TRAPPC4 lead to a significant change in NORAD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 9542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MFAP1 is perturbed and SPATA7 expression is quantified. Does this perturbation result in a significant change in SPATA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MFAP1 is perturbed and SPATA7 expression is quantified. Does this perturbation result in a significant change in SPATA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 105075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPU is associated with a significant change in MFAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPU is associated with a significant change in MFAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 52538,"You are a functional genomics specialist. In K562 cells, we perturb TSFM and monitor DHODH expression. Decide whether this perturbation leads to a significant alteration in DHODH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TSFM and monitor DHODH expression. Decide whether this perturbation leads to a significant alteration in DHODH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 25731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COG6 and examine the expression of PBX1. Does perturbing COG6 lead to a significant change in PBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COG6 and examine the expression of PBX1. Does perturbing COG6 lead to a significant change in PBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 122745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in ARHGEF28 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in ARHGEF28 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 61441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2Z and examine the expression of RXRB. Does perturbing UBE2Z lead to a significant change in RXRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2Z and examine the expression of RXRB. Does perturbing UBE2Z lead to a significant change in RXRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 13833,You are an expert in regulatory genomics. Consider data from K562 cells in which BCAR1 is perturbed and STK38L expression is observed. Does this perturbation lead to a significant difference in STK38L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BCAR1 is perturbed and STK38L expression is observed. Does this perturbation lead to a significant difference in STK38L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 47620,"You are an expert in single-cell biology and functional genomics. In K562 cells, COASY is perturbed and the expression of MCTP1 is measured. Does this perturbation cause a significant change in MCTP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COASY is perturbed and the expression of MCTP1 is measured. Does this perturbation cause a significant change in MCTP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 43038,"You are a functional genomics specialist. In K562 cells, we perturb FAF2 and monitor SEC23IP expression. Decide whether this perturbation leads to a significant alteration in SEC23IP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FAF2 and monitor SEC23IP expression. Decide whether this perturbation leads to a significant alteration in SEC23IP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 47531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GOSR2 and examine the expression of CCDC22. Does perturbing GOSR2 lead to a significant change in CCDC22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GOSR2 and examine the expression of CCDC22. Does perturbing GOSR2 lead to a significant change in CCDC22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 119353,You are an expert in regulatory genomics. Consider data from K562 cells in which SDHC is perturbed and ANKIB1 expression is observed. Does this perturbation lead to a significant difference in ANKIB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SDHC is perturbed and ANKIB1 expression is observed. Does this perturbation lead to a significant difference in ANKIB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 29733,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF207 is perturbed and TSLP expression is observed. Does this perturbation lead to a significant difference in TSLP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF207 is perturbed and TSLP expression is observed. Does this perturbation lead to a significant difference in TSLP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 80648,"You are a functional genomics specialist. In K562 cells, we perturb RGP1 and monitor MPC1 expression. Decide whether this perturbation leads to a significant alteration in MPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RGP1 and monitor MPC1 expression. Decide whether this perturbation leads to a significant alteration in MPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 89220,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP11B is perturbed and the expression of PMEPA1 is measured. Does this perturbation cause a significant change in PMEPA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP11B is perturbed and the expression of PMEPA1 is measured. Does this perturbation cause a significant change in PMEPA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 82893,You are an expert in regulatory genomics. Consider data from K562 cells in which MIS18BP1 is perturbed and TXNRD2 expression is observed. Does this perturbation lead to a significant difference in TXNRD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MIS18BP1 is perturbed and TXNRD2 expression is observed. Does this perturbation lead to a significant difference in TXNRD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 98604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USP37 and then measure expression of MARF1. Does this perturbation cause a significant change in MARF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USP37 and then measure expression of MARF1. Does this perturbation cause a significant change in MARF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 69233,You are an expert in regulatory genomics. Consider data from K562 cells in which DYNLL2 is perturbed and CDC25B expression is observed. Does this perturbation lead to a significant difference in CDC25B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DYNLL2 is perturbed and CDC25B expression is observed. Does this perturbation lead to a significant difference in CDC25B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 28833,You are an expert in regulatory genomics. Consider data from K562 cells in which SDHA is perturbed and CDCA7L expression is observed. Does this perturbation lead to a significant difference in CDCA7L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SDHA is perturbed and CDCA7L expression is observed. Does this perturbation lead to a significant difference in CDCA7L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 119497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOL12, does the expression profile of DCTN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOL12, does the expression profile of DCTN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 49941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5F1B and examine the expression of UTP25. Does perturbing ATP5F1B lead to a significant change in UTP25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5F1B and examine the expression of UTP25. Does perturbing ATP5F1B lead to a significant change in UTP25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 56598,"You are a functional genomics specialist. In K562 cells, we perturb SPC25 and monitor STK19 expression. Decide whether this perturbation leads to a significant alteration in STK19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPC25 and monitor STK19 expression. Decide whether this perturbation leads to a significant alteration in STK19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 90788,"You are a functional genomics specialist. In K562 cells, we perturb CBX1 and monitor ZBTB44 expression. Decide whether this perturbation leads to a significant alteration in ZBTB44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBX1 and monitor ZBTB44 expression. Decide whether this perturbation leads to a significant alteration in ZBTB44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 105488,"You are a functional genomics specialist. In K562 cells, we perturb RAD51C and monitor MED13L expression. Decide whether this perturbation leads to a significant alteration in MED13L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RAD51C and monitor MED13L expression. Decide whether this perturbation leads to a significant alteration in MED13L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 70295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TEN1 is associated with a significant change in RNF40 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TEN1 is associated with a significant change in RNF40 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 38027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTC1, does the expression profile of RARRES1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTC1, does the expression profile of RARRES1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 84398,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor LYPLAL1 expression. Decide whether this perturbation leads to a significant alteration in LYPLAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor LYPLAL1 expression. Decide whether this perturbation leads to a significant alteration in LYPLAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 31061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC7A6OS and examine the expression of FBN2. Does perturbing SLC7A6OS lead to a significant change in FBN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC7A6OS and examine the expression of FBN2. Does perturbing SLC7A6OS lead to a significant change in FBN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 468,"You are a functional genomics specialist. In K562 cells, we perturb METTL1 and monitor NCKAP5L expression. Decide whether this perturbation leads to a significant alteration in NCKAP5L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb METTL1 and monitor NCKAP5L expression. Decide whether this perturbation leads to a significant alteration in NCKAP5L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 67594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COG1 and then measure expression of ZNF512B. Does this perturbation cause a significant change in ZNF512B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COG1 and then measure expression of ZNF512B. Does this perturbation cause a significant change in ZNF512B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 101423,You are an expert in regulatory genomics. Consider data from K562 cells in which PRPF19 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PRPF19 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 87219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDFY3 is perturbed and APOOL expression is measured. Determine whether APOOL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDFY3 is perturbed and APOOL expression is measured. Determine whether APOOL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGAM5, does the expression profile of KDM3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGAM5, does the expression profile of KDM3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SART1 is perturbed and the expression of GTF2IRD1 is measured. Determine whether GTF2IRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SART1 is perturbed and the expression of GTF2IRD1 is measured. Determine whether GTF2IRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 11276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELOB is perturbed and the expression of ZSCAN30 is measured. Determine whether ZSCAN30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELOB is perturbed and the expression of ZSCAN30 is measured. Determine whether ZSCAN30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 61405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in SLFN5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in SLFN5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 37383,You are an expert in regulatory genomics. Consider data from K562 cells in which GINS4 is perturbed and MAU2 expression is observed. Does this perturbation lead to a significant difference in MAU2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GINS4 is perturbed and MAU2 expression is observed. Does this perturbation lead to a significant difference in MAU2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 12047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BOP1, does the expression profile of TPRG1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BOP1, does the expression profile of TPRG1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4910,"You are an expert in single-cell biology and functional genomics. In K562 cells, SBDS is perturbed and the expression of RRP36 is measured. Does this perturbation cause a significant change in RRP36 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SBDS is perturbed and the expression of RRP36 is measured. Does this perturbation cause a significant change in RRP36 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 32745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MFN2 is associated with a significant change in G0S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MFN2 is associated with a significant change in G0S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 112866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COX15 is perturbed and the expression of TGFBI is measured. Determine whether TGFBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COX15 is perturbed and the expression of TGFBI is measured. Determine whether TGFBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 101482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS27A is perturbed and NADK2 expression is quantified. Does this perturbation result in a significant change in NADK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS27A is perturbed and NADK2 expression is quantified. Does this perturbation result in a significant change in NADK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 61385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in PYCR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in PYCR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 55700,"You are an expert in single-cell biology and functional genomics. In K562 cells, RRS1 is perturbed and the expression of ITPR1 is measured. Does this perturbation cause a significant change in ITPR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RRS1 is perturbed and the expression of ITPR1 is measured. Does this perturbation cause a significant change in ITPR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 84671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KAT7 and examine the expression of SERPINB8. Does perturbing KAT7 lead to a significant change in SERPINB8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KAT7 and examine the expression of SERPINB8. Does perturbing KAT7 lead to a significant change in SERPINB8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1108,"You are a functional genomics specialist. In K562 cells, we perturb DDX46 and monitor ZNF605 expression. Decide whether this perturbation leads to a significant alteration in ZNF605 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDX46 and monitor ZNF605 expression. Decide whether this perturbation leads to a significant alteration in ZNF605 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 64392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LARS2 is perturbed and WDYHV1 expression is quantified. Does this perturbation result in a significant change in WDYHV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LARS2 is perturbed and WDYHV1 expression is quantified. Does this perturbation result in a significant change in WDYHV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 85866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBA1C is perturbed and the expression of GNA13 is measured. Determine whether GNA13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBA1C is perturbed and the expression of GNA13 is measured. Determine whether GNA13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 63951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLASRP and examine the expression of SSPN. Does perturbing CLASRP lead to a significant change in SSPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLASRP and examine the expression of SSPN. Does perturbing CLASRP lead to a significant change in SSPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 61227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS34, does the expression profile of FBN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS34, does the expression profile of FBN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 72710,"You are an expert in single-cell biology and functional genomics. In K562 cells, OXA1L is perturbed and the expression of CASP6 is measured. Does this perturbation cause a significant change in CASP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OXA1L is perturbed and the expression of CASP6 is measured. Does this perturbation cause a significant change in CASP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 28015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPC24 is associated with a significant change in FBXW11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPC24 is associated with a significant change in FBXW11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 103938,"You are a functional genomics specialist. In K562 cells, we perturb DUT and monitor WASHC2A expression. Decide whether this perturbation leads to a significant alteration in WASHC2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DUT and monitor WASHC2A expression. Decide whether this perturbation leads to a significant alteration in WASHC2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 120901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABT1 and examine the expression of PAPPA. Does perturbing ABT1 lead to a significant change in PAPPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABT1 and examine the expression of PAPPA. Does perturbing ABT1 lead to a significant change in PAPPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 119926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GEMIN7 is perturbed and the expression of RBM22 is measured. Determine whether RBM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GEMIN7 is perturbed and the expression of RBM22 is measured. Determine whether RBM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 66183,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and ZCCHC9 expression is observed. Does this perturbation lead to a significant difference in ZCCHC9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and ZCCHC9 expression is observed. Does this perturbation lead to a significant difference in ZCCHC9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 45468,"You are a functional genomics specialist. In K562 cells, we perturb DDX23 and monitor FAS expression. Decide whether this perturbation leads to a significant alteration in FAS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDX23 and monitor FAS expression. Decide whether this perturbation leads to a significant alteration in FAS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 57893,You are an expert in regulatory genomics. Consider data from K562 cells in which SRRT is perturbed and SERPINE1 expression is observed. Does this perturbation lead to a significant difference in SERPINE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRRT is perturbed and SERPINE1 expression is observed. Does this perturbation lead to a significant difference in SERPINE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 61987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF2H4, does the expression profile of SYNGR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF2H4, does the expression profile of SYNGR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 109173,You are an expert in regulatory genomics. Consider data from K562 cells in which MIS18A is perturbed and FRA10AC1 expression is observed. Does this perturbation lead to a significant difference in FRA10AC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MIS18A is perturbed and FRA10AC1 expression is observed. Does this perturbation lead to a significant difference in FRA10AC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 57877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRRT, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRRT, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 50124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ORC1 and then measure expression of TRMT13. Does this perturbation cause a significant change in TRMT13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ORC1 and then measure expression of TRMT13. Does this perturbation cause a significant change in TRMT13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 111074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LDB1 and then measure expression of SPRED1. Does this perturbation cause a significant change in SPRED1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LDB1 and then measure expression of SPRED1. Does this perturbation cause a significant change in SPRED1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 24830,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAP3 is perturbed and the expression of COQ4 is measured. Does this perturbation cause a significant change in COQ4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAP3 is perturbed and the expression of COQ4 is measured. Does this perturbation cause a significant change in COQ4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 61479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2Z is perturbed and RBM19 expression is measured. Determine whether RBM19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2Z is perturbed and RBM19 expression is measured. Determine whether RBM19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 93125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIP7 is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIP7 is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 11584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLRX3 and then measure expression of NOM1. Does this perturbation cause a significant change in NOM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLRX3 and then measure expression of NOM1. Does this perturbation cause a significant change in NOM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 39088,"You are a functional genomics specialist. In K562 cells, we perturb LAS1L and monitor RNF114 expression. Decide whether this perturbation leads to a significant alteration in RNF114 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LAS1L and monitor RNF114 expression. Decide whether this perturbation leads to a significant alteration in RNF114 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 20725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACIN1 is associated with a significant change in SLC17A5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACIN1 is associated with a significant change in SLC17A5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 53736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMG6 is perturbed and the expression of TSC2 is measured. Determine whether TSC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMG6 is perturbed and the expression of TSC2 is measured. Determine whether TSC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 71876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCAR1 is perturbed and the expression of ZIM3 is measured. Determine whether ZIM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCAR1 is perturbed and the expression of ZIM3 is measured. Determine whether ZIM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 122695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in NCOA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in NCOA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 37579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RAD21 is perturbed and WDR45 expression is measured. Determine whether WDR45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RAD21 is perturbed and WDR45 expression is measured. Determine whether WDR45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 50010,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL41 is perturbed and the expression of CENPQ is measured. Does this perturbation cause a significant change in CENPQ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL41 is perturbed and the expression of CENPQ is measured. Does this perturbation cause a significant change in CENPQ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 12216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF3J is perturbed and the expression of PNRC1 is measured. Determine whether PNRC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF3J is perturbed and the expression of PNRC1 is measured. Determine whether PNRC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 80472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL36AL is perturbed and CCDC28B expression is quantified. Does this perturbation result in a significant change in CCDC28B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL36AL is perturbed and CCDC28B expression is quantified. Does this perturbation result in a significant change in CCDC28B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 8803,You are an expert in regulatory genomics. Consider data from K562 cells in which PUF60 is perturbed and PLPP5 expression is observed. Does this perturbation lead to a significant difference in PLPP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PUF60 is perturbed and PLPP5 expression is observed. Does this perturbation lead to a significant difference in PLPP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KDM2A is perturbed and MTHFD2L expression is quantified. Does this perturbation result in a significant change in MTHFD2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KDM2A is perturbed and MTHFD2L expression is quantified. Does this perturbation result in a significant change in MTHFD2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 76530,"You are an expert in single-cell biology and functional genomics. In K562 cells, MBD3 is perturbed and the expression of CARD6 is measured. Does this perturbation cause a significant change in CARD6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MBD3 is perturbed and the expression of CARD6 is measured. Does this perturbation cause a significant change in CARD6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1028,"You are a functional genomics specialist. In K562 cells, we perturb MEN1 and monitor MIR210HG expression. Decide whether this perturbation leads to a significant alteration in MIR210HG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MEN1 and monitor MIR210HG expression. Decide whether this perturbation leads to a significant alteration in MIR210HG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 32396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZFC3H1 is perturbed and the expression of GPALPP1 is measured. Determine whether GPALPP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZFC3H1 is perturbed and the expression of GPALPP1 is measured. Determine whether GPALPP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 46012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2E is perturbed and PCSK1N expression is quantified. Does this perturbation result in a significant change in PCSK1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2E is perturbed and PCSK1N expression is quantified. Does this perturbation result in a significant change in PCSK1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 68322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NOM1 is perturbed and DNAJB1 expression is quantified. Does this perturbation result in a significant change in DNAJB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NOM1 is perturbed and DNAJB1 expression is quantified. Does this perturbation result in a significant change in DNAJB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 26725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIER1 is associated with a significant change in CLPP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIER1 is associated with a significant change in CLPP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 7362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF4E is perturbed and FBXW4 expression is quantified. Does this perturbation result in a significant change in FBXW4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF4E is perturbed and FBXW4 expression is quantified. Does this perturbation result in a significant change in FBXW4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 51185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NELFE is associated with a significant change in CLIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NELFE is associated with a significant change in CLIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 31518,"You are a functional genomics specialist. In K562 cells, we perturb ELL and monitor LIN37 expression. Decide whether this perturbation leads to a significant alteration in LIN37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ELL and monitor LIN37 expression. Decide whether this perturbation leads to a significant alteration in LIN37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 39152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL43 is perturbed and DBF4B expression is quantified. Does this perturbation result in a significant change in DBF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL43 is perturbed and DBF4B expression is quantified. Does this perturbation result in a significant change in DBF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 80044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED22 and then measure expression of PBXIP1. Does this perturbation cause a significant change in PBXIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED22 and then measure expression of PBXIP1. Does this perturbation cause a significant change in PBXIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 104569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, INPPL1 is perturbed and PFKFB4 expression is measured. Determine whether PFKFB4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, INPPL1 is perturbed and PFKFB4 expression is measured. Determine whether PFKFB4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 113646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAU2 is perturbed and the expression of NEAT1 is measured. Determine whether NEAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAU2 is perturbed and the expression of NEAT1 is measured. Determine whether NEAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 90344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPLP2 and then measure expression of SIK2. Does this perturbation cause a significant change in SIK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPLP2 and then measure expression of SIK2. Does this perturbation cause a significant change in SIK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 81074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOR2A and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOR2A and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 118069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLP1 is perturbed and TTL expression is measured. Determine whether TTL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLP1 is perturbed and TTL expression is measured. Determine whether TTL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 112922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HIST2H2AC is perturbed and SNX2 expression is quantified. Does this perturbation result in a significant change in SNX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HIST2H2AC is perturbed and SNX2 expression is quantified. Does this perturbation result in a significant change in SNX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 113783,You are an expert in regulatory genomics. Consider data from K562 cells in which RPP30 is perturbed and DENND5B expression is observed. Does this perturbation lead to a significant difference in DENND5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RPP30 is perturbed and DENND5B expression is observed. Does this perturbation lead to a significant difference in DENND5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 10733,You are an expert in regulatory genomics. Consider data from K562 cells in which NSUN4 is perturbed and TMEM132A expression is observed. Does this perturbation lead to a significant difference in TMEM132A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NSUN4 is perturbed and TMEM132A expression is observed. Does this perturbation lead to a significant difference in TMEM132A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 59442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NSA2 is perturbed and HABP4 expression is quantified. Does this perturbation result in a significant change in HABP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NSA2 is perturbed and HABP4 expression is quantified. Does this perturbation result in a significant change in HABP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 46086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB4A is perturbed and the expression of PYROXD1 is measured. Determine whether PYROXD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB4A is perturbed and the expression of PYROXD1 is measured. Determine whether PYROXD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 64077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP54, does the expression profile of EFEMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP54, does the expression profile of EFEMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 103896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIPIN is perturbed and the expression of THOC5 is measured. Determine whether THOC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIPIN is perturbed and the expression of THOC5 is measured. Determine whether THOC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 116642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POT1 is perturbed and ZNHIT1 expression is quantified. Does this perturbation result in a significant change in ZNHIT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POT1 is perturbed and ZNHIT1 expression is quantified. Does this perturbation result in a significant change in ZNHIT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 75550,"You are an expert in single-cell biology and functional genomics. In K562 cells, IPO9 is perturbed and the expression of POLR3GL is measured. Does this perturbation cause a significant change in POLR3GL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IPO9 is perturbed and the expression of POLR3GL is measured. Does this perturbation cause a significant change in POLR3GL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 40708,"You are a functional genomics specialist. In K562 cells, we perturb SETX and monitor ATP13A2 expression. Decide whether this perturbation leads to a significant alteration in ATP13A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SETX and monitor ATP13A2 expression. Decide whether this perturbation leads to a significant alteration in ATP13A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 15660,"You are an expert in single-cell biology and functional genomics. In K562 cells, LUC7L3 is perturbed and the expression of MTCL1 is measured. Does this perturbation cause a significant change in MTCL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LUC7L3 is perturbed and the expression of MTCL1 is measured. Does this perturbation cause a significant change in MTCL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 41183,You are an expert in regulatory genomics. Consider data from K562 cells in which RBM33 is perturbed and CD55 expression is observed. Does this perturbation lead to a significant difference in CD55 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RBM33 is perturbed and CD55 expression is observed. Does this perturbation lead to a significant difference in CD55 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 122366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD2 is perturbed and the expression of UEVLD is measured. Determine whether UEVLD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD2 is perturbed and the expression of UEVLD is measured. Determine whether UEVLD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG2 is perturbed and TEAD3 expression is quantified. Does this perturbation result in a significant change in TEAD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG2 is perturbed and TEAD3 expression is quantified. Does this perturbation result in a significant change in TEAD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 56650,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPA2 is perturbed and the expression of RNF139 is measured. Does this perturbation cause a significant change in RNF139 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPA2 is perturbed and the expression of RNF139 is measured. Does this perturbation cause a significant change in RNF139 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 105520,"You are an expert in single-cell biology and functional genomics. In K562 cells, RAD51C is perturbed and the expression of BBS4 is measured. Does this perturbation cause a significant change in BBS4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RAD51C is perturbed and the expression of BBS4 is measured. Does this perturbation cause a significant change in BBS4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 64075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP54 is associated with a significant change in EFEMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP54 is associated with a significant change in EFEMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 91781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CRKL and examine the expression of MBOAT2. Does perturbing CRKL lead to a significant change in MBOAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CRKL and examine the expression of MBOAT2. Does perturbing CRKL lead to a significant change in MBOAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 56524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHCY and then measure expression of CEP57. Does this perturbation cause a significant change in CEP57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHCY and then measure expression of CEP57. Does this perturbation cause a significant change in CEP57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 16863,You are an expert in regulatory genomics. Consider data from K562 cells in which NUP160 is perturbed and RNF215 expression is observed. Does this perturbation lead to a significant difference in RNF215 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NUP160 is perturbed and RNF215 expression is observed. Does this perturbation lead to a significant difference in RNF215 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 90281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANKRD17 and examine the expression of FKTN. Does perturbing ANKRD17 lead to a significant change in FKTN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANKRD17 and examine the expression of FKTN. Does perturbing ANKRD17 lead to a significant change in FKTN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 16381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM10 and examine the expression of SCMH1. Does perturbing TIMM10 lead to a significant change in SCMH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM10 and examine the expression of SCMH1. Does perturbing TIMM10 lead to a significant change in SCMH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 60741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1B2 and examine the expression of TBCK. Does perturbing ATP6V1B2 lead to a significant change in TBCK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1B2 and examine the expression of TBCK. Does perturbing ATP6V1B2 lead to a significant change in TBCK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 33549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TADA2B is perturbed and HP1BP3 expression is measured. Determine whether HP1BP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TADA2B is perturbed and HP1BP3 expression is measured. Determine whether HP1BP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 29561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED19 and examine the expression of GNG5. Does perturbing MED19 lead to a significant change in GNG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED19 and examine the expression of GNG5. Does perturbing MED19 lead to a significant change in GNG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 90948,"You are a functional genomics specialist. In K562 cells, we perturb WDR36 and monitor BCKDHB expression. Decide whether this perturbation leads to a significant alteration in BCKDHB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb WDR36 and monitor BCKDHB expression. Decide whether this perturbation leads to a significant alteration in BCKDHB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 93838,"You are a functional genomics specialist. In K562 cells, we perturb NAF1 and monitor PLSCR3 expression. Decide whether this perturbation leads to a significant alteration in PLSCR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NAF1 and monitor PLSCR3 expression. Decide whether this perturbation leads to a significant alteration in PLSCR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 43661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HERC1 and examine the expression of CDKN1A. Does perturbing HERC1 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HERC1 and examine the expression of CDKN1A. Does perturbing HERC1 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 23430,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSCB is perturbed and the expression of PIP5K1C is measured. Does this perturbation cause a significant change in PIP5K1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSCB is perturbed and the expression of PIP5K1C is measured. Does this perturbation cause a significant change in PIP5K1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 98990,"You are an expert in single-cell biology and functional genomics. In K562 cells, PHF5A is perturbed and the expression of TXNL4B is measured. Does this perturbation cause a significant change in TXNL4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PHF5A is perturbed and the expression of TXNL4B is measured. Does this perturbation cause a significant change in TXNL4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 34140,"You are an expert in single-cell biology and functional genomics. In K562 cells, FAU is perturbed and the expression of CNOT10 is measured. Does this perturbation cause a significant change in CNOT10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FAU is perturbed and the expression of CNOT10 is measured. Does this perturbation cause a significant change in CNOT10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 103581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb URM1 and examine the expression of CENPL. Does perturbing URM1 lead to a significant change in CENPL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb URM1 and examine the expression of CENPL. Does perturbing URM1 lead to a significant change in CENPL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 116092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DYNC1I2 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DYNC1I2 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 51449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ORC3 is perturbed and CYB5R4 expression is measured. Determine whether CYB5R4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ORC3 is perturbed and CYB5R4 expression is measured. Determine whether CYB5R4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 21172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VPS33A is perturbed and MYSM1 expression is quantified. Does this perturbation result in a significant change in MYSM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VPS33A is perturbed and MYSM1 expression is quantified. Does this perturbation result in a significant change in MYSM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 76718,"You are a functional genomics specialist. In K562 cells, we perturb EXOC7 and monitor ANKS1A expression. Decide whether this perturbation leads to a significant alteration in ANKS1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EXOC7 and monitor ANKS1A expression. Decide whether this perturbation leads to a significant alteration in ANKS1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 71225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NLE1 is associated with a significant change in SERTAD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NLE1 is associated with a significant change in SERTAD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 38360,"You are an expert in single-cell biology and functional genomics. In K562 cells, TUBE1 is perturbed and the expression of SEMA5A is measured. Does this perturbation cause a significant change in SEMA5A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TUBE1 is perturbed and the expression of SEMA5A is measured. Does this perturbation cause a significant change in SEMA5A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 41799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FNBP4 is perturbed and PALMD expression is measured. Determine whether PALMD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FNBP4 is perturbed and PALMD expression is measured. Determine whether PALMD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 123041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FBXO5 and examine the expression of MT1M. Does perturbing FBXO5 lead to a significant change in MT1M expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FBXO5 and examine the expression of MT1M. Does perturbing FBXO5 lead to a significant change in MT1M expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 12485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KPNA6 is associated with a significant change in TP53TG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KPNA6 is associated with a significant change in TP53TG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 107998,"You are a functional genomics specialist. In K562 cells, we perturb CYFIP1 and monitor RDH10 expression. Decide whether this perturbation leads to a significant alteration in RDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CYFIP1 and monitor RDH10 expression. Decide whether this perturbation leads to a significant alteration in RDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 15300,"You are an expert in single-cell biology and functional genomics. In K562 cells, RCCD1 is perturbed and the expression of NCSTN is measured. Does this perturbation cause a significant change in NCSTN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RCCD1 is perturbed and the expression of NCSTN is measured. Does this perturbation cause a significant change in NCSTN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 90458,"You are a functional genomics specialist. In K562 cells, we perturb KIN and monitor NARS expression. Decide whether this perturbation leads to a significant alteration in NARS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIN and monitor NARS expression. Decide whether this perturbation leads to a significant alteration in NARS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 12621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1D and examine the expression of DDIT4. Does perturbing ATP6V1D lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1D and examine the expression of DDIT4. Does perturbing ATP6V1D lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 42306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF143 is perturbed and the expression of GOLGA1 is measured. Determine whether GOLGA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF143 is perturbed and the expression of GOLGA1 is measured. Determine whether GOLGA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 47232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EFR3A is perturbed and SPSB1 expression is quantified. Does this perturbation result in a significant change in SPSB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EFR3A is perturbed and SPSB1 expression is quantified. Does this perturbation result in a significant change in SPSB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 49794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IER5. Does this perturbation cause a significant change in IER5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IER5. Does this perturbation cause a significant change in IER5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 106639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL51 is perturbed and ZBTB20 expression is measured. Determine whether ZBTB20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL51 is perturbed and ZBTB20 expression is measured. Determine whether ZBTB20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 52967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARPC2, does the expression profile of ITGA11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARPC2, does the expression profile of ITGA11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 89154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCNQ and then measure expression of PRAF2. Does this perturbation cause a significant change in PRAF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCNQ and then measure expression of PRAF2. Does this perturbation cause a significant change in PRAF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 91474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3H and then measure expression of FLII. Does this perturbation cause a significant change in FLII expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3H and then measure expression of FLII. Does this perturbation cause a significant change in FLII expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 85511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS18A and examine the expression of MTERF4. Does perturbing MRPS18A lead to a significant change in MTERF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS18A and examine the expression of MTERF4. Does perturbing MRPS18A lead to a significant change in MTERF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 70602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PABPC1 is perturbed and LONP2 expression is quantified. Does this perturbation result in a significant change in LONP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PABPC1 is perturbed and LONP2 expression is quantified. Does this perturbation result in a significant change in LONP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 40730,"You are an expert in single-cell biology and functional genomics. In K562 cells, SETX is perturbed and the expression of ERO1A is measured. Does this perturbation cause a significant change in ERO1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SETX is perturbed and the expression of ERO1A is measured. Does this perturbation cause a significant change in ERO1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 17122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS17 is perturbed and ZMYM5 expression is quantified. Does this perturbation result in a significant change in ZMYM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS17 is perturbed and ZMYM5 expression is quantified. Does this perturbation result in a significant change in ZMYM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 49619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSTF3 is perturbed and FAM32A expression is measured. Determine whether FAM32A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSTF3 is perturbed and FAM32A expression is measured. Determine whether FAM32A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 89147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS12, does the expression profile of C1GALT1C1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS12, does the expression profile of C1GALT1C1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 22854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCR and then measure expression of GBA. Does this perturbation cause a significant change in GBA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCR and then measure expression of GBA. Does this perturbation cause a significant change in GBA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 53019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, METTL16 is perturbed and ITPRID2 expression is measured. Determine whether ITPRID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, METTL16 is perturbed and ITPRID2 expression is measured. Determine whether ITPRID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 101322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSDE1 is perturbed and EEF1AKMT4 expression is quantified. Does this perturbation result in a significant change in EEF1AKMT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSDE1 is perturbed and EEF1AKMT4 expression is quantified. Does this perturbation result in a significant change in EEF1AKMT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 116697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DMAP1, does the expression profile of EPHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DMAP1, does the expression profile of EPHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 15690,"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP56 is perturbed and the expression of HIVEP1 is measured. Does this perturbation cause a significant change in HIVEP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP56 is perturbed and the expression of HIVEP1 is measured. Does this perturbation cause a significant change in HIVEP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 93625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NMD3 is associated with a significant change in MAN2B1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NMD3 is associated with a significant change in MAN2B1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 57724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCNM1 and then measure expression of C12orf4. Does this perturbation cause a significant change in C12orf4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCNM1 and then measure expression of C12orf4. Does this perturbation cause a significant change in C12orf4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 10100,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP2CB is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP2CB is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 24388,"You are a functional genomics specialist. In K562 cells, we perturb POP4 and monitor CDH10 expression. Decide whether this perturbation leads to a significant alteration in CDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb POP4 and monitor CDH10 expression. Decide whether this perturbation leads to a significant alteration in CDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 120611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of SCFD1. Does perturbing SAMM50 lead to a significant change in SCFD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of SCFD1. Does perturbing SAMM50 lead to a significant change in SCFD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 83601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT1 and examine the expression of LBR. Does perturbing ZNHIT1 lead to a significant change in LBR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT1 and examine the expression of LBR. Does perturbing ZNHIT1 lead to a significant change in LBR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 96410,"You are an expert in single-cell biology and functional genomics. In K562 cells, NHP2 is perturbed and the expression of GPRC5C is measured. Does this perturbation cause a significant change in GPRC5C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NHP2 is perturbed and the expression of GPRC5C is measured. Does this perturbation cause a significant change in GPRC5C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 43998,"You are a functional genomics specialist. In K562 cells, we perturb TMEM127 and monitor MED11 expression. Decide whether this perturbation leads to a significant alteration in MED11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMEM127 and monitor MED11 expression. Decide whether this perturbation leads to a significant alteration in MED11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 44665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAC3 is associated with a significant change in PLAC9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAC3 is associated with a significant change in PLAC9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 27275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP98 is associated with a significant change in CEP112 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP98 is associated with a significant change in CEP112 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 26776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PHB is perturbed and the expression of OGA is measured. Determine whether OGA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PHB is perturbed and the expression of OGA is measured. Determine whether OGA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 17778,"You are a functional genomics specialist. In K562 cells, we perturb CPNE7 and monitor MCC expression. Decide whether this perturbation leads to a significant alteration in MCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CPNE7 and monitor MCC expression. Decide whether this perturbation leads to a significant alteration in MCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 77729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2I is perturbed and ZCCHC8 expression is measured. Determine whether ZCCHC8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2I is perturbed and ZCCHC8 expression is measured. Determine whether ZCCHC8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 21496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SF3A1 is perturbed and the expression of SLC6A8 is measured. Determine whether SLC6A8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SF3A1 is perturbed and the expression of SLC6A8 is measured. Determine whether SLC6A8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 19113,You are an expert in regulatory genomics. Consider data from K562 cells in which GLI4 is perturbed and CCNDBP1 expression is observed. Does this perturbation lead to a significant difference in CCNDBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GLI4 is perturbed and CCNDBP1 expression is observed. Does this perturbation lead to a significant difference in CCNDBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 7157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SSBP3, does the expression profile of IFT122 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SSBP3, does the expression profile of IFT122 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 46532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NELFCD is perturbed and CHST11 expression is quantified. Does this perturbation result in a significant change in CHST11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NELFCD is perturbed and CHST11 expression is quantified. Does this perturbation result in a significant change in CHST11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 22006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPH1 is perturbed and the expression of EMC1 is measured. Determine whether EMC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPH1 is perturbed and the expression of EMC1 is measured. Determine whether EMC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 76161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTBP1 and examine the expression of CHCHD3. Does perturbing PTBP1 lead to a significant change in CHCHD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTBP1 and examine the expression of CHCHD3. Does perturbing PTBP1 lead to a significant change in CHCHD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 117216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPAN is perturbed and the expression of TAOK3 is measured. Determine whether TAOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPAN is perturbed and the expression of TAOK3 is measured. Determine whether TAOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 89667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGK1, does the expression profile of RNF111 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGK1, does the expression profile of RNF111 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 117452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3C5 is perturbed and RPS28 expression is quantified. Does this perturbation result in a significant change in RPS28 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3C5 is perturbed and RPS28 expression is quantified. Does this perturbation result in a significant change in RPS28 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 81951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCNC and examine the expression of CHPT1. Does perturbing CCNC lead to a significant change in CHPT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCNC and examine the expression of CHPT1. Does perturbing CCNC lead to a significant change in CHPT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 48223,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNHIT3 is perturbed and DUSP4 expression is observed. Does this perturbation lead to a significant difference in DUSP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNHIT3 is perturbed and DUSP4 expression is observed. Does this perturbation lead to a significant difference in DUSP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 91102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRAPPC5 is perturbed and TMEM267 expression is quantified. Does this perturbation result in a significant change in TMEM267 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRAPPC5 is perturbed and TMEM267 expression is quantified. Does this perturbation result in a significant change in TMEM267 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 121061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BANP and examine the expression of ZNF688. Does perturbing BANP lead to a significant change in ZNF688 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BANP and examine the expression of ZNF688. Does perturbing BANP lead to a significant change in ZNF688 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 98487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNC1H1, does the expression profile of ELP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNC1H1, does the expression profile of ELP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 36036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DOLK is perturbed and the expression of FBXW7 is measured. Determine whether FBXW7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DOLK is perturbed and the expression of FBXW7 is measured. Determine whether FBXW7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 83071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DCTN2 and examine the expression of ZNF107. Does perturbing DCTN2 lead to a significant change in ZNF107 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DCTN2 and examine the expression of ZNF107. Does perturbing DCTN2 lead to a significant change in ZNF107 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 115843,You are an expert in regulatory genomics. Consider data from K562 cells in which TPX2 is perturbed and INTS10 expression is observed. Does this perturbation lead to a significant difference in INTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TPX2 is perturbed and INTS10 expression is observed. Does this perturbation lead to a significant difference in INTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 59853,You are an expert in regulatory genomics. Consider data from K562 cells in which SSU72 is perturbed and DENND10 expression is observed. Does this perturbation lead to a significant difference in DENND10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SSU72 is perturbed and DENND10 expression is observed. Does this perturbation lead to a significant difference in DENND10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 103393,You are an expert in regulatory genomics. Consider data from K562 cells in which DHFR is perturbed and PCSK1N expression is observed. Does this perturbation lead to a significant difference in PCSK1N expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DHFR is perturbed and PCSK1N expression is observed. Does this perturbation lead to a significant difference in PCSK1N expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 55058,"You are a functional genomics specialist. In K562 cells, we perturb KIF4A and monitor ORC5 expression. Decide whether this perturbation leads to a significant alteration in ORC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIF4A and monitor ORC5 expression. Decide whether this perturbation leads to a significant alteration in ORC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 73112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SIN3A is perturbed and CHKB expression is quantified. Does this perturbation result in a significant change in CHKB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SIN3A is perturbed and CHKB expression is quantified. Does this perturbation result in a significant change in CHKB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 43961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM127 and examine the expression of RNF41. Does perturbing TMEM127 lead to a significant change in RNF41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM127 and examine the expression of RNF41. Does perturbing TMEM127 lead to a significant change in RNF41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 109310,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEPCE is perturbed and the expression of ARID2 is measured. Does this perturbation cause a significant change in ARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEPCE is perturbed and the expression of ARID2 is measured. Does this perturbation cause a significant change in ARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 101377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF1, does the expression profile of HRH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF1, does the expression profile of HRH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 99837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM39, does the expression profile of NFKBIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM39, does the expression profile of NFKBIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 92201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of WDR35. Does perturbing NVL lead to a significant change in WDR35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of WDR35. Does perturbing NVL lead to a significant change in WDR35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 26539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UXS1 is perturbed and FMR1 expression is measured. Determine whether FMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UXS1 is perturbed and FMR1 expression is measured. Determine whether FMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 57033,You are an expert in regulatory genomics. Consider data from K562 cells in which PKMYT1 is perturbed and AARSD1 expression is observed. Does this perturbation lead to a significant difference in AARSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PKMYT1 is perturbed and AARSD1 expression is observed. Does this perturbation lead to a significant difference in AARSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATXN10 is associated with a significant change in HLA-E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATXN10 is associated with a significant change in HLA-E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 50409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRA2B is perturbed and MALAT1 expression is measured. Determine whether MALAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRA2B is perturbed and MALAT1 expression is measured. Determine whether MALAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 113716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR2G is perturbed and the expression of LRPAP1 is measured. Determine whether LRPAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR2G is perturbed and the expression of LRPAP1 is measured. Determine whether LRPAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 28710,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCDC59 is perturbed and the expression of SLC35F5 is measured. Does this perturbation cause a significant change in SLC35F5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCDC59 is perturbed and the expression of SLC35F5 is measured. Does this perturbation cause a significant change in SLC35F5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 40212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MSRB1 is perturbed and SDR39U1 expression is quantified. Does this perturbation result in a significant change in SDR39U1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MSRB1 is perturbed and SDR39U1 expression is quantified. Does this perturbation result in a significant change in SDR39U1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 26101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TXNL4B and examine the expression of FDXR. Does perturbing TXNL4B lead to a significant change in FDXR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TXNL4B and examine the expression of FDXR. Does perturbing TXNL4B lead to a significant change in FDXR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 85738,"You are a functional genomics specialist. In K562 cells, we perturb SDC1 and monitor ATF6 expression. Decide whether this perturbation leads to a significant alteration in ATF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SDC1 and monitor ATF6 expression. Decide whether this perturbation leads to a significant alteration in ATF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 108741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED6 and examine the expression of DHRSX. Does perturbing MED6 lead to a significant change in DHRSX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED6 and examine the expression of DHRSX. Does perturbing MED6 lead to a significant change in DHRSX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 91056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPZ is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPZ is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 37921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTC4 and examine the expression of ATF1. Does perturbing TTC4 lead to a significant change in ATF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTC4 and examine the expression of ATF1. Does perturbing TTC4 lead to a significant change in ATF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 118397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KAT8, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KAT8, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 27596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL2 is perturbed and the expression of OSTF1 is measured. Determine whether OSTF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL2 is perturbed and the expression of OSTF1 is measured. Determine whether OSTF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 103741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP214 and examine the expression of TP53I3. Does perturbing NUP214 lead to a significant change in TP53I3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP214 and examine the expression of TP53I3. Does perturbing NUP214 lead to a significant change in TP53I3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 64019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD14 is perturbed and SETD5 expression is measured. Determine whether SETD5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD14 is perturbed and SETD5 expression is measured. Determine whether SETD5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 98819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL13A is perturbed and ATXN7L3B expression is measured. Determine whether ATXN7L3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL13A is perturbed and ATXN7L3B expression is measured. Determine whether ATXN7L3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 88680,"You are an expert in single-cell biology and functional genomics. In K562 cells, DTL is perturbed and the expression of MAPKAPK5-AS1 is measured. Does this perturbation cause a significant change in MAPKAPK5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DTL is perturbed and the expression of MAPKAPK5-AS1 is measured. Does this perturbation cause a significant change in MAPKAPK5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 86086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, THOC2 is perturbed and the expression of MAPRE3 is measured. Determine whether MAPRE3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, THOC2 is perturbed and the expression of MAPRE3 is measured. Determine whether MAPRE3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 72635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS26 is associated with a significant change in NFXL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS26 is associated with a significant change in NFXL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPG7 is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPG7 is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 7922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BRF1 is perturbed and TARS expression is quantified. Does this perturbation result in a significant change in TARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BRF1 is perturbed and TARS expression is quantified. Does this perturbation result in a significant change in TARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 77323,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and CSNK1G2 expression is observed. Does this perturbation lead to a significant difference in CSNK1G2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and CSNK1G2 expression is observed. Does this perturbation lead to a significant difference in CSNK1G2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 108814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS4 and then measure expression of LTA4H. Does this perturbation cause a significant change in LTA4H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS4 and then measure expression of LTA4H. Does this perturbation cause a significant change in LTA4H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 27983,You are an expert in regulatory genomics. Consider data from K562 cells in which NOB1 is perturbed and ALG1 expression is observed. Does this perturbation lead to a significant difference in ALG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NOB1 is perturbed and ALG1 expression is observed. Does this perturbation lead to a significant difference in ALG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 122933,You are an expert in regulatory genomics. Consider data from K562 cells in which METAP2 is perturbed and OAZ2 expression is observed. Does this perturbation lead to a significant difference in OAZ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which METAP2 is perturbed and OAZ2 expression is observed. Does this perturbation lead to a significant difference in OAZ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 7940,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF3 is perturbed and the expression of TERF2 is measured. Does this perturbation cause a significant change in TERF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF3 is perturbed and the expression of TERF2 is measured. Does this perturbation cause a significant change in TERF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 119815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED11 is associated with a significant change in ZSCAN16-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED11 is associated with a significant change in ZSCAN16-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 73670,"You are an expert in single-cell biology and functional genomics. In K562 cells, FBRSL1 is perturbed and the expression of SGIP1 is measured. Does this perturbation cause a significant change in SGIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FBRSL1 is perturbed and the expression of SGIP1 is measured. Does this perturbation cause a significant change in SGIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 39085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LAS1L is associated with a significant change in RNF114 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LAS1L is associated with a significant change in RNF114 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 87282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLE2 is perturbed and DSEL expression is quantified. Does this perturbation result in a significant change in DSEL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLE2 is perturbed and DSEL expression is quantified. Does this perturbation result in a significant change in DSEL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 33656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R8 is perturbed and the expression of SCFD2 is measured. Determine whether SCFD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R8 is perturbed and the expression of SCFD2 is measured. Determine whether SCFD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 104796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFB10 is perturbed and the expression of METTL2A is measured. Determine whether METTL2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFB10 is perturbed and the expression of METTL2A is measured. Determine whether METTL2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 9734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CIAO1 and then measure expression of EEPD1. Does this perturbation cause a significant change in EEPD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CIAO1 and then measure expression of EEPD1. Does this perturbation cause a significant change in EEPD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 114447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF84, does the expression profile of SYVN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF84, does the expression profile of SYVN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 106641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL51 and examine the expression of SLC6A8. Does perturbing MRPL51 lead to a significant change in SLC6A8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL51 and examine the expression of SLC6A8. Does perturbing MRPL51 lead to a significant change in SLC6A8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 29928,"You are a functional genomics specialist. In K562 cells, we perturb NSMCE1 and monitor CMTM6 expression. Decide whether this perturbation leads to a significant alteration in CMTM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NSMCE1 and monitor CMTM6 expression. Decide whether this perturbation leads to a significant alteration in CMTM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 59790,"You are an expert in single-cell biology and functional genomics. In K562 cells, LETM1 is perturbed and the expression of SLC2A8 is measured. Does this perturbation cause a significant change in SLC2A8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LETM1 is perturbed and the expression of SLC2A8 is measured. Does this perturbation cause a significant change in SLC2A8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 78692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZCCHC9 is perturbed and PITPNB expression is quantified. Does this perturbation result in a significant change in PITPNB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZCCHC9 is perturbed and PITPNB expression is quantified. Does this perturbation result in a significant change in PITPNB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 10824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MBTPS1 and then measure expression of KYAT3. Does this perturbation cause a significant change in KYAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MBTPS1 and then measure expression of KYAT3. Does this perturbation cause a significant change in KYAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 84512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COA5 is perturbed and TCP11L1 expression is quantified. Does this perturbation result in a significant change in TCP11L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COA5 is perturbed and TCP11L1 expression is quantified. Does this perturbation result in a significant change in TCP11L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 107996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CYFIP1 is perturbed and the expression of RDH10 is measured. Determine whether RDH10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CYFIP1 is perturbed and the expression of RDH10 is measured. Determine whether RDH10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 42402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFAB1 is perturbed and MBNL2 expression is quantified. Does this perturbation result in a significant change in MBNL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFAB1 is perturbed and MBNL2 expression is quantified. Does this perturbation result in a significant change in MBNL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 94277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNLL1, does the expression profile of GRINA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNLL1, does the expression profile of GRINA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 87903,You are an expert in regulatory genomics. Consider data from K562 cells in which RPAP3 is perturbed and MAPK1 expression is observed. Does this perturbation lead to a significant difference in MAPK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RPAP3 is perturbed and MAPK1 expression is observed. Does this perturbation lead to a significant difference in MAPK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 14704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP53RK and then measure expression of IL1B. Does this perturbation cause a significant change in IL1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP53RK and then measure expression of IL1B. Does this perturbation cause a significant change in IL1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 70943,You are an expert in regulatory genomics. Consider data from K562 cells in which SDR39U1 is perturbed and UBE2W expression is observed. Does this perturbation lead to a significant difference in UBE2W expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SDR39U1 is perturbed and UBE2W expression is observed. Does this perturbation lead to a significant difference in UBE2W expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 39856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBA3 is perturbed and the expression of SLC48A1 is measured. Determine whether SLC48A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBA3 is perturbed and the expression of SLC48A1 is measured. Determine whether SLC48A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 52274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP1R10 and then measure expression of TUSC3. Does this perturbation cause a significant change in TUSC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP1R10 and then measure expression of TUSC3. Does this perturbation cause a significant change in TUSC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 86129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5ME is perturbed and UQCC1 expression is measured. Determine whether UQCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5ME is perturbed and UQCC1 expression is measured. Determine whether UQCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 84521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COA5 and examine the expression of BLOC1S5. Does perturbing COA5 lead to a significant change in BLOC1S5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COA5 and examine the expression of BLOC1S5. Does perturbing COA5 lead to a significant change in BLOC1S5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 74890,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDCD7 is perturbed and the expression of BAG3 is measured. Does this perturbation cause a significant change in BAG3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDCD7 is perturbed and the expression of BAG3 is measured. Does this perturbation cause a significant change in BAG3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 119134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CYC1. Does this perturbation cause a significant change in CYC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CYC1. Does this perturbation cause a significant change in CYC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 29518,"You are a functional genomics specialist. In K562 cells, we perturb C9orf78 and monitor EMC4 expression. Decide whether this perturbation leads to a significant alteration in EMC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb C9orf78 and monitor EMC4 expression. Decide whether this perturbation leads to a significant alteration in EMC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 80385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SENP6 is associated with a significant change in FOXJ3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SENP6 is associated with a significant change in FOXJ3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 78795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA5 is associated with a significant change in CDC16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA5 is associated with a significant change in CDC16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 77727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBE2I, does the expression profile of ZCCHC8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBE2I, does the expression profile of ZCCHC8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 40919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, E2F6 is perturbed and XPA expression is measured. Determine whether XPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, E2F6 is perturbed and XPA expression is measured. Determine whether XPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 64554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAA15 and then measure expression of RTL8C. Does this perturbation cause a significant change in RTL8C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAA15 and then measure expression of RTL8C. Does this perturbation cause a significant change in RTL8C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 11561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLRX3 and examine the expression of PLAT. Does perturbing GLRX3 lead to a significant change in PLAT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLRX3 and examine the expression of PLAT. Does perturbing GLRX3 lead to a significant change in PLAT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 78718,"You are a functional genomics specialist. In K562 cells, we perturb PSMD6 and monitor BRD1 expression. Decide whether this perturbation leads to a significant alteration in BRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMD6 and monitor BRD1 expression. Decide whether this perturbation leads to a significant alteration in BRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 21554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GET1 and then measure expression of DOT1L. Does this perturbation cause a significant change in DOT1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GET1 and then measure expression of DOT1L. Does this perturbation cause a significant change in DOT1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 24789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCAPH is perturbed and STX6 expression is measured. Determine whether STX6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCAPH is perturbed and STX6 expression is measured. Determine whether STX6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 65142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AURKAIP1 is perturbed and CSPP1 expression is quantified. Does this perturbation result in a significant change in CSPP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AURKAIP1 is perturbed and CSPP1 expression is quantified. Does this perturbation result in a significant change in CSPP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC6 and then measure expression of LRPAP1. Does this perturbation cause a significant change in LRPAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC6 and then measure expression of LRPAP1. Does this perturbation cause a significant change in LRPAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 9499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB10 is perturbed and RPL14 expression is measured. Determine whether RPL14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB10 is perturbed and RPL14 expression is measured. Determine whether RPL14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 103620,"You are an expert in single-cell biology and functional genomics. In K562 cells, NUP205 is perturbed and the expression of CDH6 is measured. Does this perturbation cause a significant change in CDH6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NUP205 is perturbed and the expression of CDH6 is measured. Does this perturbation cause a significant change in CDH6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 69248,"You are a functional genomics specialist. In K562 cells, we perturb DYNLL2 and monitor DUSP4 expression. Decide whether this perturbation leads to a significant alteration in DUSP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DYNLL2 and monitor DUSP4 expression. Decide whether this perturbation leads to a significant alteration in DUSP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 25136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRPA1 is perturbed and the expression of INTS5 is measured. Determine whether INTS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRPA1 is perturbed and the expression of INTS5 is measured. Determine whether INTS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 78103,You are an expert in regulatory genomics. Consider data from K562 cells in which CWC15 is perturbed and EBAG9 expression is observed. Does this perturbation lead to a significant difference in EBAG9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CWC15 is perturbed and EBAG9 expression is observed. Does this perturbation lead to a significant difference in EBAG9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 110864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RAC1 and then measure expression of CAPZA1. Does this perturbation cause a significant change in CAPZA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RAC1 and then measure expression of CAPZA1. Does this perturbation cause a significant change in CAPZA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, N6AMT1 is perturbed and the expression of CEP57L1 is measured. Determine whether CEP57L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, N6AMT1 is perturbed and the expression of CEP57L1 is measured. Determine whether CEP57L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL36 is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL36 is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 34346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LEO1 is perturbed and the expression of RBP1 is measured. Determine whether RBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LEO1 is perturbed and the expression of RBP1 is measured. Determine whether RBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 87594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD12 and then measure expression of AP2B1. Does this perturbation cause a significant change in AP2B1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD12 and then measure expression of AP2B1. Does this perturbation cause a significant change in AP2B1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 90461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIN and examine the expression of PI4K2A. Does perturbing KIN lead to a significant change in PI4K2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIN and examine the expression of PI4K2A. Does perturbing KIN lead to a significant change in PI4K2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 65249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CWC25 is perturbed and CMTR1 expression is measured. Determine whether CMTR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CWC25 is perturbed and CMTR1 expression is measured. Determine whether CMTR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 70200,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB8 is perturbed and the expression of NOA1 is measured. Does this perturbation cause a significant change in NOA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB8 is perturbed and the expression of NOA1 is measured. Does this perturbation cause a significant change in NOA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 38374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TUBE1 and then measure expression of C2orf49. Does this perturbation cause a significant change in C2orf49 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TUBE1 and then measure expression of C2orf49. Does this perturbation cause a significant change in C2orf49 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 92191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of SLC35F6. Does perturbing NVL lead to a significant change in SLC35F6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of SLC35F6. Does perturbing NVL lead to a significant change in SLC35F6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 43578,"You are a functional genomics specialist. In K562 cells, we perturb ANKS6 and monitor TSC1 expression. Decide whether this perturbation leads to a significant alteration in TSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ANKS6 and monitor TSC1 expression. Decide whether this perturbation leads to a significant alteration in TSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 25897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of F8A1, does the expression profile of MFF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of F8A1, does the expression profile of MFF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 39027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ORC4, does the expression profile of FDXR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ORC4, does the expression profile of FDXR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 110732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF2H1 is perturbed and STYX expression is quantified. Does this perturbation result in a significant change in STYX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF2H1 is perturbed and STYX expression is quantified. Does this perturbation result in a significant change in STYX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 77873,You are an expert in regulatory genomics. Consider data from K562 cells in which RPS11 is perturbed and RTCA expression is observed. Does this perturbation lead to a significant difference in RTCA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RPS11 is perturbed and RTCA expression is observed. Does this perturbation lead to a significant difference in RTCA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 14453,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL24 is perturbed and LENG8 expression is observed. Does this perturbation lead to a significant difference in LENG8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL24 is perturbed and LENG8 expression is observed. Does this perturbation lead to a significant difference in LENG8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 119343,You are an expert in regulatory genomics. Consider data from K562 cells in which SDHC is perturbed and ARIH2 expression is observed. Does this perturbation lead to a significant difference in ARIH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SDHC is perturbed and ARIH2 expression is observed. Does this perturbation lead to a significant difference in ARIH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 91865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX37 is associated with a significant change in NUDT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX37 is associated with a significant change in NUDT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 119561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPC and examine the expression of HOOK2. Does perturbing CENPC lead to a significant change in HOOK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPC and examine the expression of HOOK2. Does perturbing CENPC lead to a significant change in HOOK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 71790,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR12 is perturbed and the expression of NACC2 is measured. Does this perturbation cause a significant change in NACC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR12 is perturbed and the expression of NACC2 is measured. Does this perturbation cause a significant change in NACC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 29811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM25 and examine the expression of PRKD3. Does perturbing RBM25 lead to a significant change in PRKD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM25 and examine the expression of PRKD3. Does perturbing RBM25 lead to a significant change in PRKD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 101832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP7 is perturbed and HSD17B11 expression is quantified. Does this perturbation result in a significant change in HSD17B11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP7 is perturbed and HSD17B11 expression is quantified. Does this perturbation result in a significant change in HSD17B11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 37916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PIAS4 is perturbed and the expression of FAT4 is measured. Determine whether FAT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PIAS4 is perturbed and the expression of FAT4 is measured. Determine whether FAT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 21117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDT1, does the expression profile of EEF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDT1, does the expression profile of EEF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 94591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of GCDH. Does perturbing AARS lead to a significant change in GCDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of GCDH. Does perturbing AARS lead to a significant change in GCDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 48179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAPC4 is perturbed and ADAM23 expression is measured. Determine whether ADAM23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAPC4 is perturbed and ADAM23 expression is measured. Determine whether ADAM23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 58351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARMC6 and examine the expression of ERBB2. Does perturbing ARMC6 lead to a significant change in ERBB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARMC6 and examine the expression of ERBB2. Does perturbing ARMC6 lead to a significant change in ERBB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 69295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL14 is associated with a significant change in NIT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL14 is associated with a significant change in NIT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 120173,You are an expert in regulatory genomics. Consider data from K562 cells in which NOP10 is perturbed and COPZ2 expression is observed. Does this perturbation lead to a significant difference in COPZ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NOP10 is perturbed and COPZ2 expression is observed. Does this perturbation lead to a significant difference in COPZ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 38970,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM161B is perturbed and the expression of APBB1IP is measured. Does this perturbation cause a significant change in APBB1IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM161B is perturbed and the expression of APBB1IP is measured. Does this perturbation cause a significant change in APBB1IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 98098,"You are a functional genomics specialist. In K562 cells, we perturb GABPB1 and monitor MDM2 expression. Decide whether this perturbation leads to a significant alteration in MDM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GABPB1 and monitor MDM2 expression. Decide whether this perturbation leads to a significant alteration in MDM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 100653,You are an expert in regulatory genomics. Consider data from K562 cells in which DNMT1 is perturbed and ATP10D expression is observed. Does this perturbation lead to a significant difference in ATP10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DNMT1 is perturbed and ATP10D expression is observed. Does this perturbation lead to a significant difference in ATP10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 39568,"You are a functional genomics specialist. In K562 cells, we perturb DNM1L and monitor MRPS27 expression. Decide whether this perturbation leads to a significant alteration in MRPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DNM1L and monitor MRPS27 expression. Decide whether this perturbation leads to a significant alteration in MRPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 25302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPRTN is perturbed and VPS37A expression is quantified. Does this perturbation result in a significant change in VPS37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPRTN is perturbed and VPS37A expression is quantified. Does this perturbation result in a significant change in VPS37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 64533,You are an expert in regulatory genomics. Consider data from K562 cells in which HAUS6 is perturbed and ZFR expression is observed. Does this perturbation lead to a significant difference in ZFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HAUS6 is perturbed and ZFR expression is observed. Does this perturbation lead to a significant difference in ZFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 59462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PMPCB is perturbed and CPE expression is quantified. Does this perturbation result in a significant change in CPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PMPCB is perturbed and CPE expression is quantified. Does this perturbation result in a significant change in CPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 41659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNASEH2C is perturbed and PPP1R9B expression is measured. Determine whether PPP1R9B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNASEH2C is perturbed and PPP1R9B expression is measured. Determine whether PPP1R9B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 32604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YTHDC1 and then measure expression of ZFP62. Does this perturbation cause a significant change in ZFP62 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YTHDC1 and then measure expression of ZFP62. Does this perturbation cause a significant change in ZFP62 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 44555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in THSD4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in THSD4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 109359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEPCE is perturbed and ANAPC1 expression is measured. Determine whether ANAPC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEPCE is perturbed and ANAPC1 expression is measured. Determine whether ANAPC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 80256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LPIN1 is perturbed and the expression of MRPL41 is measured. Determine whether MRPL41 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LPIN1 is perturbed and the expression of MRPL41 is measured. Determine whether MRPL41 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 45067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL7L1, does the expression profile of GBE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL7L1, does the expression profile of GBE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KARS is associated with a significant change in RBMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KARS is associated with a significant change in RBMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 20146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARPC4 is perturbed and the expression of RILPL1 is measured. Determine whether RILPL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARPC4 is perturbed and the expression of RILPL1 is measured. Determine whether RILPL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 121792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PEX1 is perturbed and UBFD1 expression is quantified. Does this perturbation result in a significant change in UBFD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PEX1 is perturbed and UBFD1 expression is quantified. Does this perturbation result in a significant change in UBFD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 28302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NUDT15 is perturbed and NOP56 expression is quantified. Does this perturbation result in a significant change in NOP56 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NUDT15 is perturbed and NOP56 expression is quantified. Does this perturbation result in a significant change in NOP56 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDTC1, does the expression profile of ATXN7L3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDTC1, does the expression profile of ATXN7L3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 102945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRCC6 is associated with a significant change in CREBBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRCC6 is associated with a significant change in CREBBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 67399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS29 is perturbed and SGK1 expression is measured. Determine whether SGK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS29 is perturbed and SGK1 expression is measured. Determine whether SGK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 14725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP53RK is associated with a significant change in NGLY1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP53RK is associated with a significant change in NGLY1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 100929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNF168 is perturbed and NOVA1 expression is measured. Determine whether NOVA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNF168 is perturbed and NOVA1 expression is measured. Determine whether NOVA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 16650,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS16 is perturbed and the expression of GCFC2 is measured. Does this perturbation cause a significant change in GCFC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS16 is perturbed and the expression of GCFC2 is measured. Does this perturbation cause a significant change in GCFC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 72501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GOLT1B and examine the expression of MGST1. Does perturbing GOLT1B lead to a significant change in MGST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GOLT1B and examine the expression of MGST1. Does perturbing GOLT1B lead to a significant change in MGST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6820,"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF12 is perturbed and the expression of ITCH is measured. Does this perturbation cause a significant change in ITCH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF12 is perturbed and the expression of ITCH is measured. Does this perturbation cause a significant change in ITCH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 43884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PKM and then measure expression of ERG28. Does this perturbation cause a significant change in ERG28 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PKM and then measure expression of ERG28. Does this perturbation cause a significant change in ERG28 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LTBP4 and then measure expression of SUN2. Does this perturbation cause a significant change in SUN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LTBP4 and then measure expression of SUN2. Does this perturbation cause a significant change in SUN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 120298,"You are a functional genomics specialist. In K562 cells, we perturb SPTLC1 and monitor PRKD3 expression. Decide whether this perturbation leads to a significant alteration in PRKD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPTLC1 and monitor PRKD3 expression. Decide whether this perturbation leads to a significant alteration in PRKD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 40271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ILF2 and examine the expression of ZNF581. Does perturbing ILF2 lead to a significant change in ZNF581 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ILF2 and examine the expression of ZNF581. Does perturbing ILF2 lead to a significant change in ZNF581 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 110304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED16 and then measure expression of TMEM109. Does this perturbation cause a significant change in TMEM109 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED16 and then measure expression of TMEM109. Does this perturbation cause a significant change in TMEM109 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 93170,"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM7 is perturbed and the expression of SCAMP2 is measured. Does this perturbation cause a significant change in SCAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM7 is perturbed and the expression of SCAMP2 is measured. Does this perturbation cause a significant change in SCAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 56394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELAC2 and then measure expression of MCL1. Does this perturbation cause a significant change in MCL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELAC2 and then measure expression of MCL1. Does this perturbation cause a significant change in MCL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 35870,"You are an expert in single-cell biology and functional genomics. In K562 cells, PAXBP1 is perturbed and the expression of POLR2K is measured. Does this perturbation cause a significant change in POLR2K expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PAXBP1 is perturbed and the expression of POLR2K is measured. Does this perturbation cause a significant change in POLR2K expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 119271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT6A and examine the expression of TENT5A. Does perturbing CCT6A lead to a significant change in TENT5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT6A and examine the expression of TENT5A. Does perturbing CCT6A lead to a significant change in TENT5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 40677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MLLT6, does the expression profile of DENND6A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MLLT6, does the expression profile of DENND6A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3713,You are an expert in regulatory genomics. Consider data from K562 cells in which DCTN5 is perturbed and LINC00472 expression is observed. Does this perturbation lead to a significant difference in LINC00472 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DCTN5 is perturbed and LINC00472 expression is observed. Does this perturbation lead to a significant difference in LINC00472 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 45491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX23 and examine the expression of NUS1. Does perturbing DDX23 lead to a significant change in NUS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX23 and examine the expression of NUS1. Does perturbing DDX23 lead to a significant change in NUS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 102429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DROSHA is perturbed and ITPRIPL2 expression is measured. Determine whether ITPRIPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DROSHA is perturbed and ITPRIPL2 expression is measured. Determine whether ITPRIPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 81334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL33 and then measure expression of SPPL2A. Does this perturbation cause a significant change in SPPL2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL33 and then measure expression of SPPL2A. Does this perturbation cause a significant change in SPPL2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 60305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD8 is associated with a significant change in ACOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD8 is associated with a significant change in ACOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 111860,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3B is perturbed and the expression of ALKBH7 is measured. Does this perturbation cause a significant change in ALKBH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3B is perturbed and the expression of ALKBH7 is measured. Does this perturbation cause a significant change in ALKBH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 68511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM42 and examine the expression of SESN1. Does perturbing RBM42 lead to a significant change in SESN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM42 and examine the expression of SESN1. Does perturbing RBM42 lead to a significant change in SESN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 115577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOSC8, does the expression profile of AC008969.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOSC8, does the expression profile of AC008969.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 7925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRF1 is associated with a significant change in TARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRF1 is associated with a significant change in TARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 48652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PXN is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PXN is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 75382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATF5 is perturbed and RARS2 expression is quantified. Does this perturbation result in a significant change in RARS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATF5 is perturbed and RARS2 expression is quantified. Does this perturbation result in a significant change in RARS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 94822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UMPS is perturbed and UBAP2L expression is quantified. Does this perturbation result in a significant change in UBAP2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UMPS is perturbed and UBAP2L expression is quantified. Does this perturbation result in a significant change in UBAP2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 86936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GGPS1 is perturbed and the expression of GATAD2B is measured. Determine whether GATAD2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GGPS1 is perturbed and the expression of GATAD2B is measured. Determine whether GATAD2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 57260,"You are an expert in single-cell biology and functional genomics. In K562 cells, ANAPC10 is perturbed and the expression of LNPEP is measured. Does this perturbation cause a significant change in LNPEP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ANAPC10 is perturbed and the expression of LNPEP is measured. Does this perturbation cause a significant change in LNPEP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 40146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TCERG1 is perturbed and the expression of TUBE1 is measured. Determine whether TUBE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TCERG1 is perturbed and the expression of TUBE1 is measured. Determine whether TUBE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 10134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2CB and then measure expression of ATXN7. Does this perturbation cause a significant change in ATXN7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2CB and then measure expression of ATXN7. Does this perturbation cause a significant change in ATXN7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 52646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MLST8 is perturbed and the expression of ZNF749 is measured. Determine whether ZNF749 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MLST8 is perturbed and the expression of ZNF749 is measured. Determine whether ZNF749 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 47818,"You are a functional genomics specialist. In K562 cells, we perturb SNRNP40 and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SNRNP40 and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 103497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TOP3A, does the expression profile of HABP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TOP3A, does the expression profile of HABP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 42414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFAB1 and then measure expression of ZFP90. Does this perturbation cause a significant change in ZFP90 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFAB1 and then measure expression of ZFP90. Does this perturbation cause a significant change in ZFP90 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 117104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS3 and then measure expression of GPANK1. Does this perturbation cause a significant change in GPANK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS3 and then measure expression of GPANK1. Does this perturbation cause a significant change in GPANK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 69281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNLL2 and examine the expression of GPN2. Does perturbing DYNLL2 lead to a significant change in GPN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNLL2 and examine the expression of GPN2. Does perturbing DYNLL2 lead to a significant change in GPN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 12244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3J and then measure expression of NCBP2AS2. Does this perturbation cause a significant change in NCBP2AS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3J and then measure expression of NCBP2AS2. Does this perturbation cause a significant change in NCBP2AS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 71858,"You are a functional genomics specialist. In K562 cells, we perturb BRK1 and monitor PSD3 expression. Decide whether this perturbation leads to a significant alteration in PSD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BRK1 and monitor PSD3 expression. Decide whether this perturbation leads to a significant alteration in PSD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 86345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR61 is associated with a significant change in MEST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR61 is associated with a significant change in MEST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 95619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF2BP2 is perturbed and CNOT6 expression is measured. Determine whether CNOT6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF2BP2 is perturbed and CNOT6 expression is measured. Determine whether CNOT6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 17516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFA2 is perturbed and the expression of SIAH2 is measured. Determine whether SIAH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFA2 is perturbed and the expression of SIAH2 is measured. Determine whether SIAH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 99270,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK1 is perturbed and the expression of SCMH1 is measured. Does this perturbation cause a significant change in SCMH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK1 is perturbed and the expression of SCMH1 is measured. Does this perturbation cause a significant change in SCMH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 26687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIER1, does the expression profile of ACY1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIER1, does the expression profile of ACY1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 34693,You are an expert in regulatory genomics. Consider data from K562 cells in which NOL8 is perturbed and TNFRSF10D expression is observed. Does this perturbation lead to a significant difference in TNFRSF10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NOL8 is perturbed and TNFRSF10D expression is observed. Does this perturbation lead to a significant difference in TNFRSF10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 11524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of NOL4L. Does this perturbation cause a significant change in NOL4L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of NOL4L. Does this perturbation cause a significant change in NOL4L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 36523,You are an expert in regulatory genomics. Consider data from K562 cells in which POLR2B is perturbed and UHMK1 expression is observed. Does this perturbation lead to a significant difference in UHMK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which POLR2B is perturbed and UHMK1 expression is observed. Does this perturbation lead to a significant difference in UHMK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 99148,"You are a functional genomics specialist. In K562 cells, we perturb SARNP and monitor BEND6 expression. Decide whether this perturbation leads to a significant alteration in BEND6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SARNP and monitor BEND6 expression. Decide whether this perturbation leads to a significant alteration in BEND6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 26712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIER1 is perturbed and CPA4 expression is quantified. Does this perturbation result in a significant change in CPA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIER1 is perturbed and CPA4 expression is quantified. Does this perturbation result in a significant change in CPA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 106552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PGAM1 is perturbed and PIR expression is quantified. Does this perturbation result in a significant change in PIR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PGAM1 is perturbed and PIR expression is quantified. Does this perturbation result in a significant change in PIR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 34103,You are an expert in regulatory genomics. Consider data from K562 cells in which FAU is perturbed and LRRC27 expression is observed. Does this perturbation lead to a significant difference in LRRC27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FAU is perturbed and LRRC27 expression is observed. Does this perturbation lead to a significant difference in LRRC27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 121770,"You are an expert in single-cell biology and functional genomics. In K562 cells, SF3B2 is perturbed and the expression of ZNF24 is measured. Does this perturbation cause a significant change in ZNF24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SF3B2 is perturbed and the expression of ZNF24 is measured. Does this perturbation cause a significant change in ZNF24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 113564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRPF40A and then measure expression of SEC24A. Does this perturbation cause a significant change in SEC24A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRPF40A and then measure expression of SEC24A. Does this perturbation cause a significant change in SEC24A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 20760,"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of EEF1AKNMT is measured. Does this perturbation cause a significant change in EEF1AKNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of EEF1AKNMT is measured. Does this perturbation cause a significant change in EEF1AKNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 60240,"You are an expert in single-cell biology and functional genomics. In K562 cells, YY1 is perturbed and the expression of TST is measured. Does this perturbation cause a significant change in TST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, YY1 is perturbed and the expression of TST is measured. Does this perturbation cause a significant change in TST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 41478,"You are a functional genomics specialist. In K562 cells, we perturb PSMC3 and monitor HDAC9 expression. Decide whether this perturbation leads to a significant alteration in HDAC9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PSMC3 and monitor HDAC9 expression. Decide whether this perturbation leads to a significant alteration in HDAC9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 122858,"You are a functional genomics specialist. In K562 cells, we perturb BARD1 and monitor PRUNE2 expression. Decide whether this perturbation leads to a significant alteration in PRUNE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BARD1 and monitor PRUNE2 expression. Decide whether this perturbation leads to a significant alteration in PRUNE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 103530,"You are an expert in single-cell biology and functional genomics. In K562 cells, TOP3A is perturbed and the expression of NDUFS1 is measured. Does this perturbation cause a significant change in NDUFS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TOP3A is perturbed and the expression of NDUFS1 is measured. Does this perturbation cause a significant change in NDUFS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 69620,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5PD is perturbed and the expression of WDR12 is measured. Does this perturbation cause a significant change in WDR12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5PD is perturbed and the expression of WDR12 is measured. Does this perturbation cause a significant change in WDR12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 17861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NPLOC4 and examine the expression of TTLL7. Does perturbing NPLOC4 lead to a significant change in TTLL7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NPLOC4 and examine the expression of TTLL7. Does perturbing NPLOC4 lead to a significant change in TTLL7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 69708,"You are a functional genomics specialist. In K562 cells, we perturb AHCTF1 and monitor ATF4 expression. Decide whether this perturbation leads to a significant alteration in ATF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AHCTF1 and monitor ATF4 expression. Decide whether this perturbation leads to a significant alteration in ATF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 20712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ACIN1 is perturbed and ALS2 expression is quantified. Does this perturbation result in a significant change in ALS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ACIN1 is perturbed and ALS2 expression is quantified. Does this perturbation result in a significant change in ALS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALG2, does the expression profile of ZNF107 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALG2, does the expression profile of ZNF107 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 54083,You are an expert in regulatory genomics. Consider data from K562 cells in which UTP25 is perturbed and ARHGAP1 expression is observed. Does this perturbation lead to a significant difference in ARHGAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UTP25 is perturbed and ARHGAP1 expression is observed. Does this perturbation lead to a significant difference in ARHGAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 44156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSNK2B is perturbed and the expression of SPSB3 is measured. Determine whether SPSB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSNK2B is perturbed and the expression of SPSB3 is measured. Determine whether SPSB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 17179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS17 is perturbed and MSH2 expression is measured. Determine whether MSH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS17 is perturbed and MSH2 expression is measured. Determine whether MSH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 67832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BTAF1 is perturbed and PCM1 expression is quantified. Does this perturbation result in a significant change in PCM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BTAF1 is perturbed and PCM1 expression is quantified. Does this perturbation result in a significant change in PCM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 96348,"You are a functional genomics specialist. In K562 cells, we perturb OSBP and monitor COPS5 expression. Decide whether this perturbation leads to a significant alteration in COPS5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb OSBP and monitor COPS5 expression. Decide whether this perturbation leads to a significant alteration in COPS5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 40791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP1CA and examine the expression of RPL17. Does perturbing PPP1CA lead to a significant change in RPL17 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP1CA and examine the expression of RPL17. Does perturbing PPP1CA lead to a significant change in RPL17 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 14803,You are an expert in regulatory genomics. Consider data from K562 cells in which CDC27 is perturbed and TFAP2A expression is observed. Does this perturbation lead to a significant difference in TFAP2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CDC27 is perturbed and TFAP2A expression is observed. Does this perturbation lead to a significant difference in TFAP2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS35 is perturbed and GABARAPL1 expression is measured. Determine whether GABARAPL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS35 is perturbed and GABARAPL1 expression is measured. Determine whether GABARAPL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 34301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS9 and examine the expression of GID4. Does perturbing MRPS9 lead to a significant change in GID4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS9 and examine the expression of GID4. Does perturbing MRPS9 lead to a significant change in GID4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 112147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS18C, does the expression profile of LRRC75A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS18C, does the expression profile of LRRC75A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 90607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MYCBP, does the expression profile of SGK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MYCBP, does the expression profile of SGK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 10283,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL34 is perturbed and PCDH10 expression is observed. Does this perturbation lead to a significant difference in PCDH10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL34 is perturbed and PCDH10 expression is observed. Does this perturbation lead to a significant difference in PCDH10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 25453,You are an expert in regulatory genomics. Consider data from K562 cells in which PCBP1 is perturbed and ZCCHC7 expression is observed. Does this perturbation lead to a significant difference in ZCCHC7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PCBP1 is perturbed and ZCCHC7 expression is observed. Does this perturbation lead to a significant difference in ZCCHC7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1553,You are an expert in regulatory genomics. Consider data from K562 cells in which ADRM1 is perturbed and ZNF503 expression is observed. Does this perturbation lead to a significant difference in ZNF503 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ADRM1 is perturbed and ZNF503 expression is observed. Does this perturbation lead to a significant difference in ZNF503 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 17639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCMBP is perturbed and AFDN expression is measured. Determine whether AFDN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCMBP is perturbed and AFDN expression is measured. Determine whether AFDN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 40540,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL54 is perturbed and the expression of GMPS is measured. Does this perturbation cause a significant change in GMPS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL54 is perturbed and the expression of GMPS is measured. Does this perturbation cause a significant change in GMPS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 89062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS5 is perturbed and ATP2C1 expression is quantified. Does this perturbation result in a significant change in ATP2C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS5 is perturbed and ATP2C1 expression is quantified. Does this perturbation result in a significant change in ATP2C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 13024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAA38 and then measure expression of USP3. Does this perturbation cause a significant change in USP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAA38 and then measure expression of USP3. Does this perturbation cause a significant change in USP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 25980,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRPF31 is perturbed and the expression of POLR2C is measured. Does this perturbation cause a significant change in POLR2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRPF31 is perturbed and the expression of POLR2C is measured. Does this perturbation cause a significant change in POLR2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 73262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3C3 is perturbed and JMJD1C expression is quantified. Does this perturbation result in a significant change in JMJD1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3C3 is perturbed and JMJD1C expression is quantified. Does this perturbation result in a significant change in JMJD1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 114665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNL3L is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNL3L is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 27157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GIT2, does the expression profile of GSE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GIT2, does the expression profile of GSE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 122011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CTPS1 and examine the expression of MALAT1. Does perturbing CTPS1 lead to a significant change in MALAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CTPS1 and examine the expression of MALAT1. Does perturbing CTPS1 lead to a significant change in MALAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 84690,"You are an expert in single-cell biology and functional genomics. In K562 cells, KAT7 is perturbed and the expression of KHNYN is measured. Does this perturbation cause a significant change in KHNYN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KAT7 is perturbed and the expression of KHNYN is measured. Does this perturbation cause a significant change in KHNYN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 77545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMG7 is associated with a significant change in USP53 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMG7 is associated with a significant change in USP53 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 42588,"You are a functional genomics specialist. In K562 cells, we perturb ATP6V0C and monitor NNMT expression. Decide whether this perturbation leads to a significant alteration in NNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATP6V0C and monitor NNMT expression. Decide whether this perturbation leads to a significant alteration in NNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 60348,"You are a functional genomics specialist. In K562 cells, we perturb PSMD8 and monitor CDK5 expression. Decide whether this perturbation leads to a significant alteration in CDK5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PSMD8 and monitor CDK5 expression. Decide whether this perturbation leads to a significant alteration in CDK5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 20044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYS1 and then measure expression of AASDH. Does this perturbation cause a significant change in AASDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYS1 and then measure expression of AASDH. Does this perturbation cause a significant change in AASDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 8087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF3, does the expression profile of PPP1R10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF3, does the expression profile of PPP1R10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 79419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF236 is perturbed and CHMP7 expression is measured. Determine whether CHMP7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF236 is perturbed and CHMP7 expression is measured. Determine whether CHMP7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 37424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GINS4 and then measure expression of C16orf91. Does this perturbation cause a significant change in C16orf91 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GINS4 and then measure expression of C16orf91. Does this perturbation cause a significant change in C16orf91 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 48869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LSM2 is perturbed and KIAA1549L expression is measured. Determine whether KIAA1549L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LSM2 is perturbed and KIAA1549L expression is measured. Determine whether KIAA1549L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 90900,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR36 is perturbed and the expression of PIGT is measured. Does this perturbation cause a significant change in PIGT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR36 is perturbed and the expression of PIGT is measured. Does this perturbation cause a significant change in PIGT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 24460,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYF2 is perturbed and the expression of CDC40 is measured. Does this perturbation cause a significant change in CDC40 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYF2 is perturbed and the expression of CDC40 is measured. Does this perturbation cause a significant change in CDC40 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 15718,"You are a functional genomics specialist. In K562 cells, we perturb NOP56 and monitor USP6NL expression. Decide whether this perturbation leads to a significant alteration in USP6NL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NOP56 and monitor USP6NL expression. Decide whether this perturbation leads to a significant alteration in USP6NL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 77791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DICER1 and examine the expression of PPP1R37. Does perturbing DICER1 lead to a significant change in PPP1R37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DICER1 and examine the expression of PPP1R37. Does perturbing DICER1 lead to a significant change in PPP1R37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 73071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SIN3A and examine the expression of ENTPD7. Does perturbing SIN3A lead to a significant change in ENTPD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SIN3A and examine the expression of ENTPD7. Does perturbing SIN3A lead to a significant change in ENTPD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 63864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL11 and then measure expression of GIT1. Does this perturbation cause a significant change in GIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL11 and then measure expression of GIT1. Does this perturbation cause a significant change in GIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 107928,"You are a functional genomics specialist. In K562 cells, we perturb NEPRO and monitor CNOT3 expression. Decide whether this perturbation leads to a significant alteration in CNOT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NEPRO and monitor CNOT3 expression. Decide whether this perturbation leads to a significant alteration in CNOT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 105770,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX52 is perturbed and the expression of CREBL2 is measured. Does this perturbation cause a significant change in CREBL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX52 is perturbed and the expression of CREBL2 is measured. Does this perturbation cause a significant change in CREBL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 56544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC10 and then measure expression of HPS1. Does this perturbation cause a significant change in HPS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC10 and then measure expression of HPS1. Does this perturbation cause a significant change in HPS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 95688,"You are a functional genomics specialist. In K562 cells, we perturb SMC6 and monitor THAP1 expression. Decide whether this perturbation leads to a significant alteration in THAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SMC6 and monitor THAP1 expression. Decide whether this perturbation leads to a significant alteration in THAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 19284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NPM3 and then measure expression of AKIP1. Does this perturbation cause a significant change in AKIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NPM3 and then measure expression of AKIP1. Does this perturbation cause a significant change in AKIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 112999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CMTR2 is perturbed and ARHGEF9 expression is measured. Determine whether ARHGEF9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CMTR2 is perturbed and ARHGEF9 expression is measured. Determine whether ARHGEF9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 20640,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGLN2 is perturbed and the expression of TAF9B is measured. Does this perturbation cause a significant change in TAF9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGLN2 is perturbed and the expression of TAF9B is measured. Does this perturbation cause a significant change in TAF9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 28914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC7A5 and then measure expression of SLC2A11. Does this perturbation cause a significant change in SLC2A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC7A5 and then measure expression of SLC2A11. Does this perturbation cause a significant change in SLC2A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 94681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPEN and examine the expression of UBE2W. Does perturbing SPEN lead to a significant change in UBE2W expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPEN and examine the expression of UBE2W. Does perturbing SPEN lead to a significant change in UBE2W expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1408,"You are a functional genomics specialist. In K562 cells, we perturb SERBP1 and monitor TPST1 expression. Decide whether this perturbation leads to a significant alteration in TPST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SERBP1 and monitor TPST1 expression. Decide whether this perturbation leads to a significant alteration in TPST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 79090,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf53 is perturbed and the expression of TUSC2 is measured. Does this perturbation cause a significant change in TUSC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf53 is perturbed and the expression of TUSC2 is measured. Does this perturbation cause a significant change in TUSC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 29788,"You are a functional genomics specialist. In K562 cells, we perturb RBM25 and monitor FIG4 expression. Decide whether this perturbation leads to a significant alteration in FIG4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RBM25 and monitor FIG4 expression. Decide whether this perturbation leads to a significant alteration in FIG4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 70868,"You are a functional genomics specialist. In K562 cells, we perturb KCTD10 and monitor ADAMTS1 expression. Decide whether this perturbation leads to a significant alteration in ADAMTS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KCTD10 and monitor ADAMTS1 expression. Decide whether this perturbation leads to a significant alteration in ADAMTS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 47972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C5orf30 is perturbed and GATA6 expression is quantified. Does this perturbation result in a significant change in GATA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C5orf30 is perturbed and GATA6 expression is quantified. Does this perturbation result in a significant change in GATA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 92437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS17, does the expression profile of HSD17B10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS17, does the expression profile of HSD17B10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 66121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WEE1 and examine the expression of CCDC82. Does perturbing WEE1 lead to a significant change in CCDC82 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WEE1 and examine the expression of CCDC82. Does perturbing WEE1 lead to a significant change in CCDC82 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 20757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACIN1, does the expression profile of SETD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACIN1, does the expression profile of SETD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 106981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MCM4 and examine the expression of RANBP6. Does perturbing MCM4 lead to a significant change in RANBP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MCM4 and examine the expression of RANBP6. Does perturbing MCM4 lead to a significant change in RANBP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 57,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS31, does the expression profile of CYB5R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS31, does the expression profile of CYB5R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 9,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS31 is perturbed and RNF41 expression is measured. Determine whether RNF41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS31 is perturbed and RNF41 expression is measured. Determine whether RNF41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 88688,"You are a functional genomics specialist. In K562 cells, we perturb DTL and monitor MAPKAPK5-AS1 expression. Decide whether this perturbation leads to a significant alteration in MAPKAPK5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DTL and monitor MAPKAPK5-AS1 expression. Decide whether this perturbation leads to a significant alteration in MAPKAPK5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 95502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FGFR1OP is perturbed and POC1B expression is quantified. Does this perturbation result in a significant change in POC1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FGFR1OP is perturbed and POC1B expression is quantified. Does this perturbation result in a significant change in POC1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 94168,"You are a functional genomics specialist. In K562 cells, we perturb POLR3A and monitor AP3S2 expression. Decide whether this perturbation leads to a significant alteration in AP3S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb POLR3A and monitor AP3S2 expression. Decide whether this perturbation leads to a significant alteration in AP3S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 39967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3M, does the expression profile of SNHG19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3M, does the expression profile of SNHG19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 85101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRF and examine the expression of SEC62. Does perturbing SRF lead to a significant change in SEC62 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRF and examine the expression of SEC62. Does perturbing SRF lead to a significant change in SEC62 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 18117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAM207A, does the expression profile of C1RL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAM207A, does the expression profile of C1RL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 121713,You are an expert in regulatory genomics. Consider data from K562 cells in which BRCA1 is perturbed and AL627171.2 expression is observed. Does this perturbation lead to a significant difference in AL627171.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BRCA1 is perturbed and AL627171.2 expression is observed. Does this perturbation lead to a significant difference in AL627171.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 7367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF4E, does the expression profile of FBXW4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF4E, does the expression profile of FBXW4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 94867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD11, does the expression profile of NXPE3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD11, does the expression profile of NXPE3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 119215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COQ4 is associated with a significant change in SNHG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COQ4 is associated with a significant change in SNHG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 30675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STX18 is associated with a significant change in EIF2B5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STX18 is associated with a significant change in EIF2B5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 49404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BDP1 and then measure expression of ARRDC1. Does this perturbation cause a significant change in ARRDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BDP1 and then measure expression of ARRDC1. Does this perturbation cause a significant change in ARRDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 67432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MVD is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MVD is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 53830,"You are an expert in single-cell biology and functional genomics. In K562 cells, GTPBP4 is perturbed and the expression of WRAP73 is measured. Does this perturbation cause a significant change in WRAP73 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GTPBP4 is perturbed and the expression of WRAP73 is measured. Does this perturbation cause a significant change in WRAP73 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 36421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEF2 and examine the expression of BTBD1. Does perturbing EEF2 lead to a significant change in BTBD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEF2 and examine the expression of BTBD1. Does perturbing EEF2 lead to a significant change in BTBD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 78665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZCCHC9 is associated with a significant change in TIMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZCCHC9 is associated with a significant change in TIMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 25733,You are an expert in regulatory genomics. Consider data from K562 cells in which COG6 is perturbed and PBX1 expression is observed. Does this perturbation lead to a significant difference in PBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COG6 is perturbed and PBX1 expression is observed. Does this perturbation lead to a significant difference in PBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 106581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGAM1 and examine the expression of UXT. Does perturbing PGAM1 lead to a significant change in UXT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGAM1 and examine the expression of UXT. Does perturbing PGAM1 lead to a significant change in UXT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 65301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZFR and examine the expression of ANAPC4. Does perturbing ZFR lead to a significant change in ANAPC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZFR and examine the expression of ANAPC4. Does perturbing ZFR lead to a significant change in ANAPC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 94191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF1D and examine the expression of PIK3C3. Does perturbing TAF1D lead to a significant change in PIK3C3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF1D and examine the expression of PIK3C3. Does perturbing TAF1D lead to a significant change in PIK3C3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 96485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UQCRC2 is associated with a significant change in TGFBR3L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UQCRC2 is associated with a significant change in TGFBR3L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 102188,"You are a functional genomics specialist. In K562 cells, we perturb LRR1 and monitor PEX26 expression. Decide whether this perturbation leads to a significant alteration in PEX26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LRR1 and monitor PEX26 expression. Decide whether this perturbation leads to a significant alteration in PEX26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 63465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS2 is associated with a significant change in TJAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS2 is associated with a significant change in TJAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 94635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAMAC is associated with a significant change in ANKRD12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAMAC is associated with a significant change in ANKRD12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 37101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL39 and examine the expression of EIF1B. Does perturbing RPL39 lead to a significant change in EIF1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL39 and examine the expression of EIF1B. Does perturbing RPL39 lead to a significant change in EIF1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 41750,"You are an expert in single-cell biology and functional genomics. In K562 cells, WTAP is perturbed and the expression of TRIM8 is measured. Does this perturbation cause a significant change in TRIM8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, WTAP is perturbed and the expression of TRIM8 is measured. Does this perturbation cause a significant change in TRIM8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 95313,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and SELENON expression is observed. Does this perturbation lead to a significant difference in SELENON expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and SELENON expression is observed. Does this perturbation lead to a significant difference in SELENON expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 112269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OGT is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OGT is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 86886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LARS is perturbed and the expression of RNF187 is measured. Determine whether RNF187 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LARS is perturbed and the expression of RNF187 is measured. Determine whether RNF187 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 17355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL32 is associated with a significant change in TGFBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL32 is associated with a significant change in TGFBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 62651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF5 and examine the expression of REEP5. Does perturbing TAF5 lead to a significant change in REEP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF5 and examine the expression of REEP5. Does perturbing TAF5 lead to a significant change in REEP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 121014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BANP and then measure expression of ZSCAN16-AS1. Does this perturbation cause a significant change in ZSCAN16-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BANP and then measure expression of ZSCAN16-AS1. Does this perturbation cause a significant change in ZSCAN16-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 122465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLSPN is associated with a significant change in RND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLSPN is associated with a significant change in RND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 63800,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMB6 is perturbed and the expression of NAV3 is measured. Does this perturbation cause a significant change in NAV3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMB6 is perturbed and the expression of NAV3 is measured. Does this perturbation cause a significant change in NAV3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 35178,"You are a functional genomics specialist. In K562 cells, we perturb SURF6 and monitor CDKN2B expression. Decide whether this perturbation leads to a significant alteration in CDKN2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SURF6 and monitor CDKN2B expression. Decide whether this perturbation leads to a significant alteration in CDKN2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 45438,"You are a functional genomics specialist. In K562 cells, we perturb TBPL1 and monitor CCDC174 expression. Decide whether this perturbation leads to a significant alteration in CCDC174 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TBPL1 and monitor CCDC174 expression. Decide whether this perturbation leads to a significant alteration in CCDC174 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 17499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFA2 is perturbed and CEP85L expression is measured. Determine whether CEP85L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFA2 is perturbed and CEP85L expression is measured. Determine whether CEP85L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 112331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCAPH2 and examine the expression of GDE1. Does perturbing NCAPH2 lead to a significant change in GDE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCAPH2 and examine the expression of GDE1. Does perturbing NCAPH2 lead to a significant change in GDE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 49159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GEMIN5 is perturbed and ARPC4 expression is measured. Determine whether ARPC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GEMIN5 is perturbed and ARPC4 expression is measured. Determine whether ARPC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 57334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CENPI and then measure expression of HEXIM1. Does this perturbation cause a significant change in HEXIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CENPI and then measure expression of HEXIM1. Does this perturbation cause a significant change in HEXIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 89141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS12 and examine the expression of C1GALT1C1. Does perturbing INTS12 lead to a significant change in C1GALT1C1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS12 and examine the expression of C1GALT1C1. Does perturbing INTS12 lead to a significant change in C1GALT1C1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 74436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ERCC2 is perturbed and the expression of SNX3 is measured. Determine whether SNX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ERCC2 is perturbed and the expression of SNX3 is measured. Determine whether SNX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 110144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPC and then measure expression of XPNPEP1. Does this perturbation cause a significant change in XPNPEP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPC and then measure expression of XPNPEP1. Does this perturbation cause a significant change in XPNPEP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 84323,You are an expert in regulatory genomics. Consider data from K562 cells in which TXNL4A is perturbed and C7orf26 expression is observed. Does this perturbation lead to a significant difference in C7orf26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TXNL4A is perturbed and C7orf26 expression is observed. Does this perturbation lead to a significant difference in C7orf26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 88751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSEN54 and examine the expression of JUND. Does perturbing TSEN54 lead to a significant change in JUND expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSEN54 and examine the expression of JUND. Does perturbing TSEN54 lead to a significant change in JUND expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 65919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFB6 is perturbed and RETSAT expression is measured. Determine whether RETSAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFB6 is perturbed and RETSAT expression is measured. Determine whether RETSAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 121563,You are an expert in regulatory genomics. Consider data from K562 cells in which CHMP2A is perturbed and TMEM132A expression is observed. Does this perturbation lead to a significant difference in TMEM132A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CHMP2A is perturbed and TMEM132A expression is observed. Does this perturbation lead to a significant difference in TMEM132A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 65759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ABCE1 is perturbed and RASAL2 expression is measured. Determine whether RASAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ABCE1 is perturbed and RASAL2 expression is measured. Determine whether RASAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 95726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAMM41 is perturbed and the expression of MICU3 is measured. Determine whether MICU3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAMM41 is perturbed and the expression of MICU3 is measured. Determine whether MICU3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 49227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3D, does the expression profile of ABI1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3D, does the expression profile of ABI1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 102473,You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC5 is perturbed and INSIG1 expression is observed. Does this perturbation lead to a significant difference in INSIG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC5 is perturbed and INSIG1 expression is observed. Does this perturbation lead to a significant difference in INSIG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 23801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR26 and examine the expression of NCOR1. Does perturbing WDR26 lead to a significant change in NCOR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR26 and examine the expression of NCOR1. Does perturbing WDR26 lead to a significant change in NCOR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 39793,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL28 is perturbed and C9orf16 expression is observed. Does this perturbation lead to a significant difference in C9orf16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL28 is perturbed and C9orf16 expression is observed. Does this perturbation lead to a significant difference in C9orf16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 22894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMA3 and then measure expression of ATP6V1A. Does this perturbation cause a significant change in ATP6V1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMA3 and then measure expression of ATP6V1A. Does this perturbation cause a significant change in ATP6V1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 91040,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPZ is perturbed and the expression of PCBD2 is measured. Does this perturbation cause a significant change in PCBD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPZ is perturbed and the expression of PCBD2 is measured. Does this perturbation cause a significant change in PCBD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5718,"You are a functional genomics specialist. In K562 cells, we perturb INTS3 and monitor GNPDA1 expression. Decide whether this perturbation leads to a significant alteration in GNPDA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb INTS3 and monitor GNPDA1 expression. Decide whether this perturbation leads to a significant alteration in GNPDA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 96618,"You are a functional genomics specialist. In K562 cells, we perturb WDHD1 and monitor MMAB expression. Decide whether this perturbation leads to a significant alteration in MMAB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb WDHD1 and monitor MMAB expression. Decide whether this perturbation leads to a significant alteration in MMAB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1190,"You are an expert in single-cell biology and functional genomics. In K562 cells, PGAM5 is perturbed and the expression of ZBTB40 is measured. Does this perturbation cause a significant change in ZBTB40 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PGAM5 is perturbed and the expression of ZBTB40 is measured. Does this perturbation cause a significant change in ZBTB40 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 44303,You are an expert in regulatory genomics. Consider data from K562 cells in which ZW10 is perturbed and NOM1 expression is observed. Does this perturbation lead to a significant difference in NOM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZW10 is perturbed and NOM1 expression is observed. Does this perturbation lead to a significant difference in NOM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 48597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMU1, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMU1, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 14635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLD1 is associated with a significant change in WBP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLD1 is associated with a significant change in WBP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 92754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL21 and then measure expression of AGPAT5. Does this perturbation cause a significant change in AGPAT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL21 and then measure expression of AGPAT5. Does this perturbation cause a significant change in AGPAT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 104418,"You are a functional genomics specialist. In K562 cells, we perturb PDHA1 and monitor SPOP expression. Decide whether this perturbation leads to a significant alteration in SPOP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PDHA1 and monitor SPOP expression. Decide whether this perturbation leads to a significant alteration in SPOP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 55595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LAMB1 is associated with a significant change in IFRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LAMB1 is associated with a significant change in IFRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 7428,"You are a functional genomics specialist. In K562 cells, we perturb MRPL35 and monitor MT-ATP8 expression. Decide whether this perturbation leads to a significant alteration in MT-ATP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRPL35 and monitor MT-ATP8 expression. Decide whether this perturbation leads to a significant alteration in MT-ATP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF4H is perturbed and CD3EAP expression is quantified. Does this perturbation result in a significant change in CD3EAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF4H is perturbed and CD3EAP expression is quantified. Does this perturbation result in a significant change in CD3EAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 37816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of ANTXR2 is measured. Determine whether ANTXR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of ANTXR2 is measured. Determine whether ANTXR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 29847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ENO1, does the expression profile of TPST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ENO1, does the expression profile of TPST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 84482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COA5 is perturbed and THAP3 expression is quantified. Does this perturbation result in a significant change in THAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COA5 is perturbed and THAP3 expression is quantified. Does this perturbation result in a significant change in THAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 518,"You are a functional genomics specialist. In K562 cells, we perturb VPS35 and monitor CA9 expression. Decide whether this perturbation leads to a significant alteration in CA9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb VPS35 and monitor CA9 expression. Decide whether this perturbation leads to a significant alteration in CA9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 116928,"You are a functional genomics specialist. In K562 cells, we perturb MRPL45 and monitor RPL10 expression. Decide whether this perturbation leads to a significant alteration in RPL10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL45 and monitor RPL10 expression. Decide whether this perturbation leads to a significant alteration in RPL10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 32553,You are an expert in regulatory genomics. Consider data from K562 cells in which MBTPS2 is perturbed and CMTM3 expression is observed. Does this perturbation lead to a significant difference in CMTM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MBTPS2 is perturbed and CMTM3 expression is observed. Does this perturbation lead to a significant difference in CMTM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 82771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHX29 and examine the expression of ZNF143. Does perturbing DHX29 lead to a significant change in ZNF143 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHX29 and examine the expression of ZNF143. Does perturbing DHX29 lead to a significant change in ZNF143 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 53484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4G2 and then measure expression of TAMM41. Does this perturbation cause a significant change in TAMM41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4G2 and then measure expression of TAMM41. Does this perturbation cause a significant change in TAMM41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 116765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TWISTNB is associated with a significant change in C9orf16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TWISTNB is associated with a significant change in C9orf16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 93236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS6 is perturbed and the expression of SULF1 is measured. Determine whether SULF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS6 is perturbed and the expression of SULF1 is measured. Determine whether SULF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 99979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC1 is perturbed and HMGCR expression is measured. Determine whether HMGCR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC1 is perturbed and HMGCR expression is measured. Determine whether HMGCR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 79672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR3 is perturbed and IFT20 expression is quantified. Does this perturbation result in a significant change in IFT20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR3 is perturbed and IFT20 expression is quantified. Does this perturbation result in a significant change in IFT20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 111921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CPSF4 and examine the expression of VCPIP1. Does perturbing CPSF4 lead to a significant change in VCPIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CPSF4 and examine the expression of VCPIP1. Does perturbing CPSF4 lead to a significant change in VCPIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 92584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM13 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM13 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 108109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, INO80 is perturbed and TRNP1 expression is measured. Determine whether TRNP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, INO80 is perturbed and TRNP1 expression is measured. Determine whether TRNP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 51234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSGEP and then measure expression of NR1D2. Does this perturbation cause a significant change in NR1D2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSGEP and then measure expression of NR1D2. Does this perturbation cause a significant change in NR1D2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 96000,"You are an expert in single-cell biology and functional genomics. In K562 cells, AP2A1 is perturbed and the expression of TAX1BP3 is measured. Does this perturbation cause a significant change in TAX1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AP2A1 is perturbed and the expression of TAX1BP3 is measured. Does this perturbation cause a significant change in TAX1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 15682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LUC7L3 is perturbed and RCN2 expression is quantified. Does this perturbation result in a significant change in RCN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LUC7L3 is perturbed and RCN2 expression is quantified. Does this perturbation result in a significant change in RCN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 113597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUGT1, does the expression profile of VGLL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUGT1, does the expression profile of VGLL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 111199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR82 is perturbed and CD276 expression is measured. Determine whether CD276 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR82 is perturbed and CD276 expression is measured. Determine whether CD276 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 111637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UTP18, does the expression profile of BORCS5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UTP18, does the expression profile of BORCS5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 34589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, INTS14 is perturbed and KRT80 expression is measured. Determine whether KRT80 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, INTS14 is perturbed and KRT80 expression is measured. Determine whether KRT80 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 97277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USPL1, does the expression profile of PHLDA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USPL1, does the expression profile of PHLDA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 90077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP1A1, does the expression profile of IGF2BP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP1A1, does the expression profile of IGF2BP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 45423,You are an expert in regulatory genomics. Consider data from K562 cells in which TBPL1 is perturbed and PUS1 expression is observed. Does this perturbation lead to a significant difference in PUS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TBPL1 is perturbed and PUS1 expression is observed. Does this perturbation lead to a significant difference in PUS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 44305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZW10 is associated with a significant change in NOM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZW10 is associated with a significant change in NOM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 75706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GABPA is perturbed and the expression of LYST is measured. Determine whether LYST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GABPA is perturbed and the expression of LYST is measured. Determine whether LYST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 123523,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3F is perturbed and RXRB expression is observed. Does this perturbation lead to a significant difference in RXRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3F is perturbed and RXRB expression is observed. Does this perturbation lead to a significant difference in RXRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 48965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZWINT is associated with a significant change in MRPS10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZWINT is associated with a significant change in MRPS10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 34326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS9 is perturbed and the expression of SLC38A6 is measured. Determine whether SLC38A6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS9 is perturbed and the expression of SLC38A6 is measured. Determine whether SLC38A6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 41427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED14, does the expression profile of SLC25A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED14, does the expression profile of SLC25A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 94199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF1D is perturbed and PIK3C3 expression is measured. Determine whether PIK3C3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF1D is perturbed and PIK3C3 expression is measured. Determine whether PIK3C3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 100044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HMBOX1 and then measure expression of MED31. Does this perturbation cause a significant change in MED31 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HMBOX1 and then measure expression of MED31. Does this perturbation cause a significant change in MED31 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 117297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRKRA, does the expression profile of UBTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRKRA, does the expression profile of UBTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 74308,"You are a functional genomics specialist. In K562 cells, we perturb TIMM9 and monitor PPP6R1 expression. Decide whether this perturbation leads to a significant alteration in PPP6R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM9 and monitor PPP6R1 expression. Decide whether this perturbation leads to a significant alteration in PPP6R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TFAM is perturbed and CA9 expression is measured. Determine whether CA9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TFAM is perturbed and CA9 expression is measured. Determine whether CA9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 70372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF4 is perturbed and RNF14 expression is quantified. Does this perturbation result in a significant change in RNF14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF4 is perturbed and RNF14 expression is quantified. Does this perturbation result in a significant change in RNF14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 104853,You are an expert in regulatory genomics. Consider data from K562 cells in which RAB18 is perturbed and NUTM2B-AS1 expression is observed. Does this perturbation lead to a significant difference in NUTM2B-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RAB18 is perturbed and NUTM2B-AS1 expression is observed. Does this perturbation lead to a significant difference in NUTM2B-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 117871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABCB7 and examine the expression of TGFB2. Does perturbing ABCB7 lead to a significant change in TGFB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABCB7 and examine the expression of TGFB2. Does perturbing ABCB7 lead to a significant change in TGFB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 43582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ANKS6 is perturbed and NFIA expression is quantified. Does this perturbation result in a significant change in NFIA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ANKS6 is perturbed and NFIA expression is quantified. Does this perturbation result in a significant change in NFIA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 112794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISG20L2 and then measure expression of UBQLN2. Does this perturbation cause a significant change in UBQLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISG20L2 and then measure expression of UBQLN2. Does this perturbation cause a significant change in UBQLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFS5, does the expression profile of ARL6IP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFS5, does the expression profile of ARL6IP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 117632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDC45 is perturbed and TBC1D10B expression is quantified. Does this perturbation result in a significant change in TBC1D10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDC45 is perturbed and TBC1D10B expression is quantified. Does this perturbation result in a significant change in TBC1D10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 40013,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3M is perturbed and PRPF3 expression is observed. Does this perturbation lead to a significant difference in PRPF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3M is perturbed and PRPF3 expression is observed. Does this perturbation lead to a significant difference in PRPF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 55263,You are an expert in regulatory genomics. Consider data from K562 cells in which MCRS1 is perturbed and DDIT3 expression is observed. Does this perturbation lead to a significant difference in DDIT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MCRS1 is perturbed and DDIT3 expression is observed. Does this perturbation lead to a significant difference in DDIT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 9438,"You are a functional genomics specialist. In K562 cells, we perturb EIF3L and monitor TRERF1 expression. Decide whether this perturbation leads to a significant alteration in TRERF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF3L and monitor TRERF1 expression. Decide whether this perturbation leads to a significant alteration in TRERF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 36597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BUD31, does the expression profile of PDCD7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BUD31, does the expression profile of PDCD7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 40317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ILF2, does the expression profile of FUCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ILF2, does the expression profile of FUCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 98579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP37 is perturbed and SMURF2 expression is measured. Determine whether SMURF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP37 is perturbed and SMURF2 expression is measured. Determine whether SMURF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 14170,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARIH1 is perturbed and the expression of IGHMBP2 is measured. Does this perturbation cause a significant change in IGHMBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARIH1 is perturbed and the expression of IGHMBP2 is measured. Does this perturbation cause a significant change in IGHMBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 79044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CS and then measure expression of SPRY2. Does this perturbation cause a significant change in SPRY2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CS and then measure expression of SPRY2. Does this perturbation cause a significant change in SPRY2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 122531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP1CB and examine the expression of LTBP3. Does perturbing PPP1CB lead to a significant change in LTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP1CB and examine the expression of LTBP3. Does perturbing PPP1CB lead to a significant change in LTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 103603,You are an expert in regulatory genomics. Consider data from K562 cells in which URM1 is perturbed and DHTKD1 expression is observed. Does this perturbation lead to a significant difference in DHTKD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which URM1 is perturbed and DHTKD1 expression is observed. Does this perturbation lead to a significant difference in DHTKD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 81792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF5A is perturbed and CYB5R1 expression is quantified. Does this perturbation result in a significant change in CYB5R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF5A is perturbed and CYB5R1 expression is quantified. Does this perturbation result in a significant change in CYB5R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 103738,"You are a functional genomics specialist. In K562 cells, we perturb NUP214 and monitor LMO4 expression. Decide whether this perturbation leads to a significant alteration in LMO4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NUP214 and monitor LMO4 expression. Decide whether this perturbation leads to a significant alteration in LMO4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 18994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSEN34 and then measure expression of PIAS4. Does this perturbation cause a significant change in PIAS4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSEN34 and then measure expression of PIAS4. Does this perturbation cause a significant change in PIAS4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 75446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNOT11 is perturbed and the expression of ELMSAN1 is measured. Determine whether ELMSAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNOT11 is perturbed and the expression of ELMSAN1 is measured. Determine whether ELMSAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 16443,You are an expert in regulatory genomics. Consider data from K562 cells in which PPP2CA is perturbed and SLC35G1 expression is observed. Does this perturbation lead to a significant difference in SLC35G1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PPP2CA is perturbed and SLC35G1 expression is observed. Does this perturbation lead to a significant difference in SLC35G1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 22242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP5 is perturbed and GREM1 expression is quantified. Does this perturbation result in a significant change in GREM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP5 is perturbed and GREM1 expression is quantified. Does this perturbation result in a significant change in GREM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 66569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAST is perturbed and ABCD4 expression is measured. Determine whether ABCD4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAST is perturbed and ABCD4 expression is measured. Determine whether ABCD4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 92101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF1B and examine the expression of FAM162A. Does perturbing TAF1B lead to a significant change in FAM162A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF1B and examine the expression of FAM162A. Does perturbing TAF1B lead to a significant change in FAM162A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 67636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CXXC1 is perturbed and the expression of RAB30-DT is measured. Determine whether RAB30-DT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CXXC1 is perturbed and the expression of RAB30-DT is measured. Determine whether RAB30-DT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 92613,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM13 is perturbed and HSPA4L expression is observed. Does this perturbation lead to a significant difference in HSPA4L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM13 is perturbed and HSPA4L expression is observed. Does this perturbation lead to a significant difference in HSPA4L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 76869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDC1 is perturbed and ING4 expression is measured. Determine whether ING4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDC1 is perturbed and ING4 expression is measured. Determine whether ING4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 89145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS12 is associated with a significant change in C1GALT1C1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS12 is associated with a significant change in C1GALT1C1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 53450,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4G2 is perturbed and the expression of PLEKHA3 is measured. Does this perturbation cause a significant change in PLEKHA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4G2 is perturbed and the expression of PLEKHA3 is measured. Does this perturbation cause a significant change in PLEKHA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 115120,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R15B is perturbed and the expression of DUSP22 is measured. Does this perturbation cause a significant change in DUSP22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R15B is perturbed and the expression of DUSP22 is measured. Does this perturbation cause a significant change in DUSP22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 61073,You are an expert in regulatory genomics. Consider data from K562 cells in which CPSF6 is perturbed and NFAT5 expression is observed. Does this perturbation lead to a significant difference in NFAT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CPSF6 is perturbed and NFAT5 expression is observed. Does this perturbation lead to a significant difference in NFAT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6168,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor SLC35B3 expression. Decide whether this perturbation leads to a significant alteration in SLC35B3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor SLC35B3 expression. Decide whether this perturbation leads to a significant alteration in SLC35B3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 123127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED21, does the expression profile of DOCK5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED21, does the expression profile of DOCK5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 113399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNOT9 is perturbed and HLA-B expression is measured. Determine whether HLA-B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNOT9 is perturbed and HLA-B expression is measured. Determine whether HLA-B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 73740,"You are an expert in single-cell biology and functional genomics. In K562 cells, SP2 is perturbed and the expression of RAB31 is measured. Does this perturbation cause a significant change in RAB31 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SP2 is perturbed and the expression of RAB31 is measured. Does this perturbation cause a significant change in RAB31 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 39304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CABIN1 and then measure expression of PMEPA1. Does this perturbation cause a significant change in PMEPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CABIN1 and then measure expression of PMEPA1. Does this perturbation cause a significant change in PMEPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 65945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD11 is associated with a significant change in HMOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD11 is associated with a significant change in HMOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 10087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDCD6IP, does the expression profile of EEF1E1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDCD6IP, does the expression profile of EEF1E1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 58909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR3 is perturbed and MT-ND4L expression is measured. Determine whether MT-ND4L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR3 is perturbed and MT-ND4L expression is measured. Determine whether MT-ND4L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 108200,"You are an expert in single-cell biology and functional genomics. In K562 cells, PIK3R4 is perturbed and the expression of FAM149B1 is measured. Does this perturbation cause a significant change in FAM149B1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PIK3R4 is perturbed and the expression of FAM149B1 is measured. Does this perturbation cause a significant change in FAM149B1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 32572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MBTPS2 is perturbed and PMAIP1 expression is quantified. Does this perturbation result in a significant change in PMAIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MBTPS2 is perturbed and PMAIP1 expression is quantified. Does this perturbation result in a significant change in PMAIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 65381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS10 and examine the expression of RPS15A. Does perturbing MRPS10 lead to a significant change in RPS15A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS10 and examine the expression of RPS15A. Does perturbing MRPS10 lead to a significant change in RPS15A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 109687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of DCTN6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of DCTN6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6603,You are an expert in regulatory genomics. Consider data from K562 cells in which SART1 is perturbed and ITPR1 expression is observed. Does this perturbation lead to a significant difference in ITPR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SART1 is perturbed and ITPR1 expression is observed. Does this perturbation lead to a significant difference in ITPR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 66632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL23 is perturbed and SPAG4 expression is quantified. Does this perturbation result in a significant change in SPAG4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL23 is perturbed and SPAG4 expression is quantified. Does this perturbation result in a significant change in SPAG4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 91457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3H, does the expression profile of SNRPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3H, does the expression profile of SNRPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5013,You are an expert in regulatory genomics. Consider data from K562 cells in which TBCA is perturbed and ANKLE2 expression is observed. Does this perturbation lead to a significant difference in ANKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TBCA is perturbed and ANKLE2 expression is observed. Does this perturbation lead to a significant difference in ANKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 105153,You are an expert in regulatory genomics. Consider data from K562 cells in which SUPT6H is perturbed and SLC25A29 expression is observed. Does this perturbation lead to a significant difference in SLC25A29 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SUPT6H is perturbed and SLC25A29 expression is observed. Does this perturbation lead to a significant difference in SLC25A29 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 50242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNOT1 is perturbed and CEP57L1 expression is quantified. Does this perturbation result in a significant change in CEP57L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNOT1 is perturbed and CEP57L1 expression is quantified. Does this perturbation result in a significant change in CEP57L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 86638,"You are a functional genomics specialist. In K562 cells, we perturb CDC42 and monitor ARL6IP5 expression. Decide whether this perturbation leads to a significant alteration in ARL6IP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDC42 and monitor ARL6IP5 expression. Decide whether this perturbation leads to a significant alteration in ARL6IP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDTC1 is perturbed and the expression of KIF13B is measured. Determine whether KIF13B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDTC1 is perturbed and the expression of KIF13B is measured. Determine whether KIF13B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5653,You are an expert in regulatory genomics. Consider data from K562 cells in which CDC6 is perturbed and UBE2E2 expression is observed. Does this perturbation lead to a significant difference in UBE2E2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDC6 is perturbed and UBE2E2 expression is observed. Does this perturbation lead to a significant difference in UBE2E2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 94916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPD1 is perturbed and the expression of GADD45A is measured. Determine whether GADD45A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPD1 is perturbed and the expression of GADD45A is measured. Determine whether GADD45A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 100811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC1 and examine the expression of SERINC3. Does perturbing THOC1 lead to a significant change in SERINC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC1 and examine the expression of SERINC3. Does perturbing THOC1 lead to a significant change in SERINC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 26264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CENPK and then measure expression of PXDC1. Does this perturbation cause a significant change in PXDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CENPK and then measure expression of PXDC1. Does this perturbation cause a significant change in PXDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 85630,"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM5 is perturbed and the expression of RND3 is measured. Does this perturbation cause a significant change in RND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM5 is perturbed and the expression of RND3 is measured. Does this perturbation cause a significant change in RND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 8883,You are an expert in regulatory genomics. Consider data from K562 cells in which NARS is perturbed and DYRK4 expression is observed. Does this perturbation lead to a significant difference in DYRK4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NARS is perturbed and DYRK4 expression is observed. Does this perturbation lead to a significant difference in DYRK4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 99074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NELFA and then measure expression of ITGAV. Does this perturbation cause a significant change in ITGAV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NELFA and then measure expression of ITGAV. Does this perturbation cause a significant change in ITGAV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 118144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL9 and then measure expression of C1orf122. Does this perturbation cause a significant change in C1orf122 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL9 and then measure expression of C1orf122. Does this perturbation cause a significant change in C1orf122 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 111085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LDB1 is associated with a significant change in MYH10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LDB1 is associated with a significant change in MYH10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 20373,You are an expert in regulatory genomics. Consider data from K562 cells in which THAP1 is perturbed and SUPT7L expression is observed. Does this perturbation lead to a significant difference in SUPT7L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which THAP1 is perturbed and SUPT7L expression is observed. Does this perturbation lead to a significant difference in SUPT7L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 50496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of SCD is measured. Determine whether SCD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of SCD is measured. Determine whether SCD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 88113,You are an expert in regulatory genomics. Consider data from K562 cells in which UPF1 is perturbed and DNAJC17 expression is observed. Does this perturbation lead to a significant difference in DNAJC17 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UPF1 is perturbed and DNAJC17 expression is observed. Does this perturbation lead to a significant difference in DNAJC17 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 96361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM48 and examine the expression of NDST2. Does perturbing RBM48 lead to a significant change in NDST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM48 and examine the expression of NDST2. Does perturbing RBM48 lead to a significant change in NDST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 52984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARPC2 and then measure expression of PPIB. Does this perturbation cause a significant change in PPIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARPC2 and then measure expression of PPIB. Does this perturbation cause a significant change in PPIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 60616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR1C is perturbed and the expression of PALMD is measured. Determine whether PALMD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR1C is perturbed and the expression of PALMD is measured. Determine whether PALMD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 78618,"You are a functional genomics specialist. In K562 cells, we perturb NFYB and monitor IFI27L2 expression. Decide whether this perturbation leads to a significant alteration in IFI27L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NFYB and monitor IFI27L2 expression. Decide whether this perturbation leads to a significant alteration in IFI27L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 66685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK2 is associated with a significant change in DDX55 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK2 is associated with a significant change in DDX55 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 122705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in TXN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in TXN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 79241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD13 and examine the expression of CEBPZOS. Does perturbing PSMD13 lead to a significant change in CEBPZOS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD13 and examine the expression of CEBPZOS. Does perturbing PSMD13 lead to a significant change in CEBPZOS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 85019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, METTL14 is perturbed and RBMX2 expression is measured. Determine whether RBMX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, METTL14 is perturbed and RBMX2 expression is measured. Determine whether RBMX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 32687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MOK, does the expression profile of HSPB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MOK, does the expression profile of HSPB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 56,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS31 is perturbed and the expression of CYB5R1 is measured. Determine whether CYB5R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS31 is perturbed and the expression of CYB5R1 is measured. Determine whether CYB5R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 9314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRORP and then measure expression of WEE1. Does this perturbation cause a significant change in WEE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRORP and then measure expression of WEE1. Does this perturbation cause a significant change in WEE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 119259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COQ4 is perturbed and PDSS2 expression is measured. Determine whether PDSS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COQ4 is perturbed and PDSS2 expression is measured. Determine whether PDSS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 41576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL38 is perturbed and the expression of YIPF5 is measured. Determine whether YIPF5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL38 is perturbed and the expression of YIPF5 is measured. Determine whether YIPF5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 59622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ACD is perturbed and DENND10 expression is quantified. Does this perturbation result in a significant change in DENND10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ACD is perturbed and DENND10 expression is quantified. Does this perturbation result in a significant change in DENND10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 25548,"You are a functional genomics specialist. In K562 cells, we perturb UCHL5 and monitor RBL2 expression. Decide whether this perturbation leads to a significant alteration in RBL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UCHL5 and monitor RBL2 expression. Decide whether this perturbation leads to a significant alteration in RBL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 30900,"You are an expert in single-cell biology and functional genomics. In K562 cells, GARS is perturbed and the expression of ASMTL is measured. Does this perturbation cause a significant change in ASMTL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GARS is perturbed and the expression of ASMTL is measured. Does this perturbation cause a significant change in ASMTL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 12234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3J and then measure expression of MED4. Does this perturbation cause a significant change in MED4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3J and then measure expression of MED4. Does this perturbation cause a significant change in MED4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 113523,You are an expert in regulatory genomics. Consider data from K562 cells in which PRPF40A is perturbed and SNHG1 expression is observed. Does this perturbation lead to a significant difference in SNHG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRPF40A is perturbed and SNHG1 expression is observed. Does this perturbation lead to a significant difference in SNHG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 18254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL20 and then measure expression of HERC3. Does this perturbation cause a significant change in HERC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL20 and then measure expression of HERC3. Does this perturbation cause a significant change in HERC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 30997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAD2L2, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAD2L2, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 90160,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB4 is perturbed and the expression of NDST1 is measured. Does this perturbation cause a significant change in NDST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB4 is perturbed and the expression of NDST1 is measured. Does this perturbation cause a significant change in NDST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 107307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM4, does the expression profile of AC016831.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM4, does the expression profile of AC016831.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 12483,You are an expert in regulatory genomics. Consider data from K562 cells in which KPNA6 is perturbed and TP53TG1 expression is observed. Does this perturbation lead to a significant difference in TP53TG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KPNA6 is perturbed and TP53TG1 expression is observed. Does this perturbation lead to a significant difference in TP53TG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 46962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAE1 is perturbed and AC016831.7 expression is quantified. Does this perturbation result in a significant change in AC016831.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAE1 is perturbed and AC016831.7 expression is quantified. Does this perturbation result in a significant change in AC016831.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 77678,"You are a functional genomics specialist. In K562 cells, we perturb RPS21 and monitor RALGAPA1 expression. Decide whether this perturbation leads to a significant alteration in RALGAPA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RPS21 and monitor RALGAPA1 expression. Decide whether this perturbation leads to a significant alteration in RALGAPA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 82464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX5B and then measure expression of NAV3. Does this perturbation cause a significant change in NAV3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX5B and then measure expression of NAV3. Does this perturbation cause a significant change in NAV3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 104770,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB10 is perturbed and the expression of ITFG1 is measured. Does this perturbation cause a significant change in ITFG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB10 is perturbed and the expression of ITFG1 is measured. Does this perturbation cause a significant change in ITFG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 45363,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and NOSIP expression is observed. Does this perturbation lead to a significant difference in NOSIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and NOSIP expression is observed. Does this perturbation lead to a significant difference in NOSIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 8579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL19 is perturbed and IRF1 expression is measured. Determine whether IRF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL19 is perturbed and IRF1 expression is measured. Determine whether IRF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 77188,"You are a functional genomics specialist. In K562 cells, we perturb LONP1 and monitor LRRC75A expression. Decide whether this perturbation leads to a significant alteration in LRRC75A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb LONP1 and monitor LRRC75A expression. Decide whether this perturbation leads to a significant alteration in LRRC75A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 46409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TUBGCP2 is perturbed and MEGF9 expression is measured. Determine whether MEGF9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TUBGCP2 is perturbed and MEGF9 expression is measured. Determine whether MEGF9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 51221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSGEP and examine the expression of PCSK1N. Does perturbing OSGEP lead to a significant change in PCSK1N expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSGEP and examine the expression of PCSK1N. Does perturbing OSGEP lead to a significant change in PCSK1N expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 72043,You are an expert in regulatory genomics. Consider data from K562 cells in which PMPCA is perturbed and TMEM39A expression is observed. Does this perturbation lead to a significant difference in TMEM39A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PMPCA is perturbed and TMEM39A expression is observed. Does this perturbation lead to a significant difference in TMEM39A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 104016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISY1 is perturbed and the expression of AMZ2 is measured. Determine whether AMZ2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISY1 is perturbed and the expression of AMZ2 is measured. Determine whether AMZ2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 98479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DYNC1H1 is perturbed and WDR11 expression is measured. Determine whether WDR11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DYNC1H1 is perturbed and WDR11 expression is measured. Determine whether WDR11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3688,"You are a functional genomics specialist. In K562 cells, we perturb DTYMK and monitor CCNDBP1 expression. Decide whether this perturbation leads to a significant alteration in CCNDBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DTYMK and monitor CCNDBP1 expression. Decide whether this perturbation leads to a significant alteration in CCNDBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 25213,You are an expert in regulatory genomics. Consider data from K562 cells in which RRP15 is perturbed and JPX expression is observed. Does this perturbation lead to a significant difference in JPX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RRP15 is perturbed and JPX expression is observed. Does this perturbation lead to a significant difference in JPX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPA1 is perturbed and the expression of BBS2 is measured. Determine whether BBS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPA1 is perturbed and the expression of BBS2 is measured. Determine whether BBS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 16321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TCP1 and examine the expression of COPG1. Does perturbing TCP1 lead to a significant change in COPG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TCP1 and examine the expression of COPG1. Does perturbing TCP1 lead to a significant change in COPG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 58912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARPC1B is perturbed and BCL2L13 expression is quantified. Does this perturbation result in a significant change in BCL2L13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARPC1B is perturbed and BCL2L13 expression is quantified. Does this perturbation result in a significant change in BCL2L13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 12023,You are an expert in regulatory genomics. Consider data from K562 cells in which BOP1 is perturbed and MBNL2 expression is observed. Does this perturbation lead to a significant difference in MBNL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BOP1 is perturbed and MBNL2 expression is observed. Does this perturbation lead to a significant difference in MBNL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 54474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GAPDH and then measure expression of DYRK3. Does this perturbation cause a significant change in DYRK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GAPDH and then measure expression of DYRK3. Does this perturbation cause a significant change in DYRK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 32907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCKAP1, does the expression profile of CCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCKAP1, does the expression profile of CCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 88174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AAAS and then measure expression of PMVK. Does this perturbation cause a significant change in PMVK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AAAS and then measure expression of PMVK. Does this perturbation cause a significant change in PMVK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 140,"You are an expert in single-cell biology and functional genomics. In K562 cells, WBP1 is perturbed and the expression of ZBTB24 is measured. Does this perturbation cause a significant change in ZBTB24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, WBP1 is perturbed and the expression of ZBTB24 is measured. Does this perturbation cause a significant change in ZBTB24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 41252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCDC137 is perturbed and SNX1 expression is quantified. Does this perturbation result in a significant change in SNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCDC137 is perturbed and SNX1 expression is quantified. Does this perturbation result in a significant change in SNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 81588,"You are a functional genomics specialist. In K562 cells, we perturb VPS18 and monitor RNF145 expression. Decide whether this perturbation leads to a significant alteration in RNF145 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb VPS18 and monitor RNF145 expression. Decide whether this perturbation leads to a significant alteration in RNF145 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and DNAH14 expression is quantified. Does this perturbation result in a significant change in DNAH14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and DNAH14 expression is quantified. Does this perturbation result in a significant change in DNAH14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 27126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GIT2 is perturbed and the expression of SMIM29 is measured. Determine whether SMIM29 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GIT2 is perturbed and the expression of SMIM29 is measured. Determine whether SMIM29 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 44841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GAK and examine the expression of ZDHHC17. Does perturbing GAK lead to a significant change in ZDHHC17 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GAK and examine the expression of ZDHHC17. Does perturbing GAK lead to a significant change in ZDHHC17 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 62403,You are an expert in regulatory genomics. Consider data from K562 cells in which GLE1 is perturbed and DPP7 expression is observed. Does this perturbation lead to a significant difference in DPP7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GLE1 is perturbed and DPP7 expression is observed. Does this perturbation lead to a significant difference in DPP7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 73858,"You are a functional genomics specialist. In K562 cells, we perturb TERF1 and monitor CDC42BPA expression. Decide whether this perturbation leads to a significant alteration in CDC42BPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TERF1 and monitor CDC42BPA expression. Decide whether this perturbation leads to a significant alteration in CDC42BPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 77055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHCHD2 is associated with a significant change in RNF216 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHCHD2 is associated with a significant change in RNF216 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 56496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHCY is perturbed and the expression of SMARCD1 is measured. Determine whether SMARCD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHCY is perturbed and the expression of SMARCD1 is measured. Determine whether SMARCD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 112586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C7orf50 is perturbed and the expression of ASAH1 is measured. Determine whether ASAH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C7orf50 is perturbed and the expression of ASAH1 is measured. Determine whether ASAH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 15546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PAF1 is perturbed and the expression of SHOX2 is measured. Determine whether SHOX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PAF1 is perturbed and the expression of SHOX2 is measured. Determine whether SHOX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 75192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FTSJ3 is perturbed and TMCO3 expression is quantified. Does this perturbation result in a significant change in TMCO3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FTSJ3 is perturbed and TMCO3 expression is quantified. Does this perturbation result in a significant change in TMCO3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 109604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC25A26 and then measure expression of MRPS7. Does this perturbation cause a significant change in MRPS7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC25A26 and then measure expression of MRPS7. Does this perturbation cause a significant change in MRPS7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 69646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5PD is perturbed and the expression of STIM1 is measured. Determine whether STIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5PD is perturbed and the expression of STIM1 is measured. Determine whether STIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 117301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRKRA and examine the expression of ENTPD7. Does perturbing PRKRA lead to a significant change in ENTPD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRKRA and examine the expression of ENTPD7. Does perturbing PRKRA lead to a significant change in ENTPD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 46366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBGCP2 is perturbed and the expression of CYFIP2 is measured. Determine whether CYFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBGCP2 is perturbed and the expression of CYFIP2 is measured. Determine whether CYFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 52638,"You are a functional genomics specialist. In K562 cells, we perturb MLST8 and monitor WIPI2 expression. Decide whether this perturbation leads to a significant alteration in WIPI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MLST8 and monitor WIPI2 expression. Decide whether this perturbation leads to a significant alteration in WIPI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 15355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN2 is associated with a significant change in PROSER3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN2 is associated with a significant change in PROSER3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 102656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of GAS5 is measured. Determine whether GAS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of GAS5 is measured. Determine whether GAS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 99862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBM39 is perturbed and CLP1 expression is quantified. Does this perturbation result in a significant change in CLP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBM39 is perturbed and CLP1 expression is quantified. Does this perturbation result in a significant change in CLP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 31069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC7A6OS is perturbed and FBN2 expression is measured. Determine whether FBN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC7A6OS is perturbed and FBN2 expression is measured. Determine whether FBN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 14361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TNPO3 and examine the expression of ZMYM3. Does perturbing TNPO3 lead to a significant change in ZMYM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TNPO3 and examine the expression of ZMYM3. Does perturbing TNPO3 lead to a significant change in ZMYM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 80989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX18 is perturbed and FAM20C expression is measured. Determine whether FAM20C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX18 is perturbed and FAM20C expression is measured. Determine whether FAM20C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 76735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RINT1 is associated with a significant change in YIPF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RINT1 is associated with a significant change in YIPF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 117026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPIA is perturbed and the expression of UNC45A is measured. Determine whether UNC45A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPIA is perturbed and the expression of UNC45A is measured. Determine whether UNC45A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 33855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFAF7 is associated with a significant change in PXDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFAF7 is associated with a significant change in PXDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 101663,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC62 is perturbed and TRIT1 expression is observed. Does this perturbation lead to a significant difference in TRIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC62 is perturbed and TRIT1 expression is observed. Does this perturbation lead to a significant difference in TRIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 57909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRRT is perturbed and ZNF23 expression is measured. Determine whether ZNF23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRRT is perturbed and ZNF23 expression is measured. Determine whether ZNF23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 87893,You are an expert in regulatory genomics. Consider data from K562 cells in which RPAP3 is perturbed and KDM5B expression is observed. Does this perturbation lead to a significant difference in KDM5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RPAP3 is perturbed and KDM5B expression is observed. Does this perturbation lead to a significant difference in KDM5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 23856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF13 is perturbed and the expression of FANCL is measured. Determine whether FANCL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF13 is perturbed and the expression of FANCL is measured. Determine whether FANCL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6608,"You are a functional genomics specialist. In K562 cells, we perturb SART1 and monitor ITPR1 expression. Decide whether this perturbation leads to a significant alteration in ITPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SART1 and monitor ITPR1 expression. Decide whether this perturbation leads to a significant alteration in ITPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 99546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFB3 is perturbed and the expression of MIR222HG is measured. Determine whether MIR222HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFB3 is perturbed and the expression of MIR222HG is measured. Determine whether MIR222HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 30276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF6 is perturbed and the expression of EIF2A is measured. Determine whether EIF2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF6 is perturbed and the expression of EIF2A is measured. Determine whether EIF2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 57462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SUDS3 is perturbed and CEBPB expression is quantified. Does this perturbation result in a significant change in CEBPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SUDS3 is perturbed and CEBPB expression is quantified. Does this perturbation result in a significant change in CEBPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 53014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to METTL16 and then measure expression of ITPRID2. Does this perturbation cause a significant change in ITPRID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to METTL16 and then measure expression of ITPRID2. Does this perturbation cause a significant change in ITPRID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 116101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNC1I2 and examine the expression of CREBRF. Does perturbing DYNC1I2 lead to a significant change in CREBRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNC1I2 and examine the expression of CREBRF. Does perturbing DYNC1I2 lead to a significant change in CREBRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 97737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOP14, does the expression profile of ANXA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOP14, does the expression profile of ANXA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 107119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPAIN is perturbed and PHPT1 expression is measured. Determine whether PHPT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPAIN is perturbed and PHPT1 expression is measured. Determine whether PHPT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 114894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS11 and then measure expression of PLPP4. Does this perturbation cause a significant change in PLPP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS11 and then measure expression of PLPP4. Does this perturbation cause a significant change in PLPP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 12782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PCBP2 is perturbed and LARP4B expression is quantified. Does this perturbation result in a significant change in LARP4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PCBP2 is perturbed and LARP4B expression is quantified. Does this perturbation result in a significant change in LARP4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 29506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C9orf78 is perturbed and the expression of ARL6IP1 is measured. Determine whether ARL6IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C9orf78 is perturbed and the expression of ARL6IP1 is measured. Determine whether ARL6IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 7695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OIP5 is associated with a significant change in PSTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OIP5 is associated with a significant change in PSTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 23714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TFRC and then measure expression of PLPP3. Does this perturbation cause a significant change in PLPP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TFRC and then measure expression of PLPP3. Does this perturbation cause a significant change in PLPP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 57196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB6A is perturbed and the expression of RBM5 is measured. Determine whether RBM5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB6A is perturbed and the expression of RBM5 is measured. Determine whether RBM5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3730,"You are an expert in single-cell biology and functional genomics. In K562 cells, DCTN5 is perturbed and the expression of CSTF2T is measured. Does this perturbation cause a significant change in CSTF2T expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DCTN5 is perturbed and the expression of CSTF2T is measured. Does this perturbation cause a significant change in CSTF2T expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 34824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PCID2 and then measure expression of DHRS7. Does this perturbation cause a significant change in DHRS7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PCID2 and then measure expression of DHRS7. Does this perturbation cause a significant change in DHRS7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 35801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNRPF and examine the expression of ABHD8. Does perturbing SNRPF lead to a significant change in ABHD8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNRPF and examine the expression of ABHD8. Does perturbing SNRPF lead to a significant change in ABHD8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 44943,You are an expert in regulatory genomics. Consider data from K562 cells in which SF3B4 is perturbed and SMC5 expression is observed. Does this perturbation lead to a significant difference in SMC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SF3B4 is perturbed and SMC5 expression is observed. Does this perturbation lead to a significant difference in SMC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 85733,You are an expert in regulatory genomics. Consider data from K562 cells in which SDC1 is perturbed and ATF6 expression is observed. Does this perturbation lead to a significant difference in ATF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SDC1 is perturbed and ATF6 expression is observed. Does this perturbation lead to a significant difference in ATF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 38743,You are an expert in regulatory genomics. Consider data from K562 cells in which NCAPD2 is perturbed and ZHX1 expression is observed. Does this perturbation lead to a significant difference in ZHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NCAPD2 is perturbed and ZHX1 expression is observed. Does this perturbation lead to a significant difference in ZHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 46906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHORDC1 is perturbed and the expression of SNHG14 is measured. Determine whether SNHG14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHORDC1 is perturbed and the expression of SNHG14 is measured. Determine whether SNHG14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 92073,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL37 is perturbed and CD47 expression is observed. Does this perturbation lead to a significant difference in CD47 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL37 is perturbed and CD47 expression is observed. Does this perturbation lead to a significant difference in CD47 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 22424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HLA-C and then measure expression of SNRPC. Does this perturbation cause a significant change in SNRPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HLA-C and then measure expression of SNRPC. Does this perturbation cause a significant change in SNRPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 123550,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP4B is perturbed and the expression of HLA-E is measured. Does this perturbation cause a significant change in HLA-E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP4B is perturbed and the expression of HLA-E is measured. Does this perturbation cause a significant change in HLA-E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 55651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RRS1 and examine the expression of ATP6AP1. Does perturbing RRS1 lead to a significant change in ATP6AP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RRS1 and examine the expression of ATP6AP1. Does perturbing RRS1 lead to a significant change in ATP6AP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 102805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMB4 is associated with a significant change in SLC38A6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMB4 is associated with a significant change in SLC38A6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 109110,"You are an expert in single-cell biology and functional genomics. In K562 cells, GTF2H2 is perturbed and the expression of TAF10 is measured. Does this perturbation cause a significant change in TAF10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GTF2H2 is perturbed and the expression of TAF10 is measured. Does this perturbation cause a significant change in TAF10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 115388,"You are a functional genomics specialist. In K562 cells, we perturb PSMA2 and monitor KIAA1217 expression. Decide whether this perturbation leads to a significant alteration in KIAA1217 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMA2 and monitor KIAA1217 expression. Decide whether this perturbation leads to a significant alteration in KIAA1217 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 98037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRSF2, does the expression profile of NORAD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRSF2, does the expression profile of NORAD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 25013,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and ICE2 expression is observed. Does this perturbation lead to a significant difference in ICE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and ICE2 expression is observed. Does this perturbation lead to a significant difference in ICE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 27898,"You are a functional genomics specialist. In K562 cells, we perturb CHCHD4 and monitor GOT1 expression. Decide whether this perturbation leads to a significant alteration in GOT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CHCHD4 and monitor GOT1 expression. Decide whether this perturbation leads to a significant alteration in GOT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 74087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBBP5, does the expression profile of TRIM24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBBP5, does the expression profile of TRIM24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 62689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF5 is perturbed and ORMDL1 expression is measured. Determine whether ORMDL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF5 is perturbed and ORMDL1 expression is measured. Determine whether ORMDL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 11522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and NOL4L expression is quantified. Does this perturbation result in a significant change in NOL4L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and NOL4L expression is quantified. Does this perturbation result in a significant change in NOL4L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 86818,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A9 and monitor TCEAL1 expression. Decide whether this perturbation leads to a significant alteration in TCEAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A9 and monitor TCEAL1 expression. Decide whether this perturbation leads to a significant alteration in TCEAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 44517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSEN2, does the expression profile of EIF4A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSEN2, does the expression profile of EIF4A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 33610,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R8 is perturbed and the expression of MDK is measured. Does this perturbation cause a significant change in MDK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R8 is perturbed and the expression of MDK is measured. Does this perturbation cause a significant change in MDK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 61756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSA is perturbed and the expression of SCN9A is measured. Determine whether SCN9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSA is perturbed and the expression of SCN9A is measured. Determine whether SCN9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 34616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS14 is perturbed and the expression of ARAF is measured. Determine whether ARAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS14 is perturbed and the expression of ARAF is measured. Determine whether ARAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 105291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBCB and examine the expression of CPEB4. Does perturbing TBCB lead to a significant change in CPEB4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBCB and examine the expression of CPEB4. Does perturbing TBCB lead to a significant change in CPEB4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 23726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFRC is perturbed and the expression of FST is measured. Determine whether FST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFRC is perturbed and the expression of FST is measured. Determine whether FST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 53454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4G2 and then measure expression of PLEKHA3. Does this perturbation cause a significant change in PLEKHA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4G2 and then measure expression of PLEKHA3. Does this perturbation cause a significant change in PLEKHA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 11160,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of RPP14 is measured. Does this perturbation cause a significant change in RPP14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of RPP14 is measured. Does this perturbation cause a significant change in RPP14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 28519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFV2 is perturbed and UBXN6 expression is measured. Determine whether UBXN6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFV2 is perturbed and UBXN6 expression is measured. Determine whether UBXN6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 7605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL37 is associated with a significant change in CASP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL37 is associated with a significant change in CASP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 62019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2H4 is perturbed and CAPN7 expression is measured. Determine whether CAPN7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2H4 is perturbed and CAPN7 expression is measured. Determine whether CAPN7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 24102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and PI4K2A expression is quantified. Does this perturbation result in a significant change in PI4K2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and PI4K2A expression is quantified. Does this perturbation result in a significant change in PI4K2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 67538,"You are a functional genomics specialist. In K562 cells, we perturb BCS1L and monitor CREBRF expression. Decide whether this perturbation leads to a significant alteration in CREBRF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BCS1L and monitor CREBRF expression. Decide whether this perturbation leads to a significant alteration in CREBRF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 30872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GARS is perturbed and CEBPG expression is quantified. Does this perturbation result in a significant change in CEBPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GARS is perturbed and CEBPG expression is quantified. Does this perturbation result in a significant change in CEBPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 22548,"You are a functional genomics specialist. In K562 cells, we perturb ZC3H4 and monitor IFFO2 expression. Decide whether this perturbation leads to a significant alteration in IFFO2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZC3H4 and monitor IFFO2 expression. Decide whether this perturbation leads to a significant alteration in IFFO2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTMA is perturbed and ZNF561 expression is measured. Determine whether ZNF561 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTMA is perturbed and ZNF561 expression is measured. Determine whether ZNF561 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 72252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and GSDME expression is quantified. Does this perturbation result in a significant change in GSDME expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and GSDME expression is quantified. Does this perturbation result in a significant change in GSDME expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 86266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCF11 is perturbed and the expression of AK1 is measured. Determine whether AK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCF11 is perturbed and the expression of AK1 is measured. Determine whether AK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 70921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SDR39U1 and examine the expression of TBC1D2B. Does perturbing SDR39U1 lead to a significant change in TBC1D2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SDR39U1 and examine the expression of TBC1D2B. Does perturbing SDR39U1 lead to a significant change in TBC1D2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 59905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOSC4 is associated with a significant change in CKAP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOSC4 is associated with a significant change in CKAP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 118993,You are an expert in regulatory genomics. Consider data from K562 cells in which RPP38 is perturbed and CREB3L2 expression is observed. Does this perturbation lead to a significant difference in CREB3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RPP38 is perturbed and CREB3L2 expression is observed. Does this perturbation lead to a significant difference in CREB3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 79325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED8 is associated with a significant change in TPRG1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED8 is associated with a significant change in TPRG1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 94260,"You are an expert in single-cell biology and functional genomics. In K562 cells, DYNLL1 is perturbed and the expression of DOK1 is measured. Does this perturbation cause a significant change in DOK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DYNLL1 is perturbed and the expression of DOK1 is measured. Does this perturbation cause a significant change in DOK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 121634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR75 and then measure expression of MDM2. Does this perturbation cause a significant change in MDM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR75 and then measure expression of MDM2. Does this perturbation cause a significant change in MDM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 43923,You are an expert in regulatory genomics. Consider data from K562 cells in which TNRC6A is perturbed and SART1 expression is observed. Does this perturbation lead to a significant difference in SART1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TNRC6A is perturbed and SART1 expression is observed. Does this perturbation lead to a significant difference in SART1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 56888,"You are a functional genomics specialist. In K562 cells, we perturb LIN54 and monitor UBE2D1 expression. Decide whether this perturbation leads to a significant alteration in UBE2D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb LIN54 and monitor UBE2D1 expression. Decide whether this perturbation leads to a significant alteration in UBE2D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 45635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MPHOSPH6 is associated with a significant change in PCMTD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MPHOSPH6 is associated with a significant change in PCMTD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 100445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GFER is associated with a significant change in CHPF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GFER is associated with a significant change in CHPF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 45951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NSMCE2 and examine the expression of TIGAR. Does perturbing NSMCE2 lead to a significant change in TIGAR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NSMCE2 and examine the expression of TIGAR. Does perturbing NSMCE2 lead to a significant change in TIGAR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 93823,You are an expert in regulatory genomics. Consider data from K562 cells in which CTU2 is perturbed and FNDC3A expression is observed. Does this perturbation lead to a significant difference in FNDC3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CTU2 is perturbed and FNDC3A expression is observed. Does this perturbation lead to a significant difference in FNDC3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 21166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS33A is perturbed and the expression of CIC is measured. Determine whether CIC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS33A is perturbed and the expression of CIC is measured. Determine whether CIC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 109942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRRAP is perturbed and WDR83 expression is quantified. Does this perturbation result in a significant change in WDR83 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRRAP is perturbed and WDR83 expression is quantified. Does this perturbation result in a significant change in WDR83 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 111480,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMG1 is perturbed and the expression of RPAIN is measured. Does this perturbation cause a significant change in RPAIN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMG1 is perturbed and the expression of RPAIN is measured. Does this perturbation cause a significant change in RPAIN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 108665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOP16 is associated with a significant change in PTS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOP16 is associated with a significant change in PTS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRMT112 is perturbed and ATP6V1H expression is quantified. Does this perturbation result in a significant change in ATP6V1H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRMT112 is perturbed and ATP6V1H expression is quantified. Does this perturbation result in a significant change in ATP6V1H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2093,You are an expert in regulatory genomics. Consider data from K562 cells in which TRMT112 is perturbed and AMFR expression is observed. Does this perturbation lead to a significant difference in AMFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TRMT112 is perturbed and AMFR expression is observed. Does this perturbation lead to a significant difference in AMFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 80957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX18, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX18, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 69143,You are an expert in regulatory genomics. Consider data from K562 cells in which EEF1A1 is perturbed and MPC2 expression is observed. Does this perturbation lead to a significant difference in MPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EEF1A1 is perturbed and MPC2 expression is observed. Does this perturbation lead to a significant difference in MPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 38811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NDUFA6 and examine the expression of RBBP8. Does perturbing NDUFA6 lead to a significant change in RBBP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NDUFA6 and examine the expression of RBBP8. Does perturbing NDUFA6 lead to a significant change in RBBP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 27558,"You are a functional genomics specialist. In K562 cells, we perturb GTF2A1 and monitor HSDL2 expression. Decide whether this perturbation leads to a significant alteration in HSDL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GTF2A1 and monitor HSDL2 expression. Decide whether this perturbation leads to a significant alteration in HSDL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 91235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCAF1 is associated with a significant change in FIP1L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCAF1 is associated with a significant change in FIP1L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 93166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIP7 is perturbed and the expression of TMED10 is measured. Determine whether TMED10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIP7 is perturbed and the expression of TMED10 is measured. Determine whether TMED10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 50263,You are an expert in regulatory genomics. Consider data from K562 cells in which HUWE1 is perturbed and NFASC expression is observed. Does this perturbation lead to a significant difference in NFASC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HUWE1 is perturbed and NFASC expression is observed. Does this perturbation lead to a significant difference in NFASC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 112427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf25, does the expression profile of CERS5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf25, does the expression profile of CERS5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 90749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1B is perturbed and DUSP22 expression is measured. Determine whether DUSP22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1B is perturbed and DUSP22 expression is measured. Determine whether DUSP22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 74185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL14 is associated with a significant change in IL4R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL14 is associated with a significant change in IL4R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 92022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRBD1 is perturbed and ADAM12 expression is quantified. Does this perturbation result in a significant change in ADAM12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRBD1 is perturbed and ADAM12 expression is quantified. Does this perturbation result in a significant change in ADAM12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTEN and then measure expression of PPP3CC. Does this perturbation cause a significant change in PPP3CC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTEN and then measure expression of PPP3CC. Does this perturbation cause a significant change in PPP3CC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 41909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC25A10 is perturbed and ETHE1 expression is measured. Determine whether ETHE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC25A10 is perturbed and ETHE1 expression is measured. Determine whether ETHE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 119756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMB7 is perturbed and the expression of NEK1 is measured. Determine whether NEK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMB7 is perturbed and the expression of NEK1 is measured. Determine whether NEK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 114554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPT16H and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPT16H and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 65816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLNS1A is perturbed and the expression of SLFN12 is measured. Determine whether SLFN12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLNS1A is perturbed and the expression of SLFN12 is measured. Determine whether SLFN12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 59806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LETM1 is perturbed and the expression of EGR1 is measured. Determine whether EGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LETM1 is perturbed and the expression of EGR1 is measured. Determine whether EGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 77415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RCC1 is associated with a significant change in ING4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RCC1 is associated with a significant change in ING4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 80189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS2 is perturbed and PGM2 expression is measured. Determine whether PGM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS2 is perturbed and PGM2 expression is measured. Determine whether PGM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 121123,You are an expert in regulatory genomics. Consider data from K562 cells in which MED10 is perturbed and LATS1 expression is observed. Does this perturbation lead to a significant difference in LATS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MED10 is perturbed and LATS1 expression is observed. Does this perturbation lead to a significant difference in LATS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5790,"You are an expert in single-cell biology and functional genomics. In K562 cells, MCM3 is perturbed and the expression of HEG1 is measured. Does this perturbation cause a significant change in HEG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MCM3 is perturbed and the expression of HEG1 is measured. Does this perturbation cause a significant change in HEG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 30002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NELFB is perturbed and EDRF1 expression is quantified. Does this perturbation result in a significant change in EDRF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NELFB is perturbed and EDRF1 expression is quantified. Does this perturbation result in a significant change in EDRF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 117989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPDL is perturbed and ZCCHC7 expression is measured. Determine whether ZCCHC7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPDL is perturbed and ZCCHC7 expression is measured. Determine whether ZCCHC7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 121430,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAP18 is perturbed and the expression of TAF12 is measured. Does this perturbation cause a significant change in TAF12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAP18 is perturbed and the expression of TAF12 is measured. Does this perturbation cause a significant change in TAF12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and DNAJC3 expression is measured. Determine whether DNAJC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and DNAJC3 expression is measured. Determine whether DNAJC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 116789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TWISTNB is perturbed and NMNAT2 expression is measured. Determine whether NMNAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TWISTNB is perturbed and NMNAT2 expression is measured. Determine whether NMNAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 91855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX37 is associated with a significant change in COMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX37 is associated with a significant change in COMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 39164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL43 and then measure expression of KCMF1. Does this perturbation cause a significant change in KCMF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL43 and then measure expression of KCMF1. Does this perturbation cause a significant change in KCMF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 100164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX33 and then measure expression of GOLGA4. Does this perturbation cause a significant change in GOLGA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX33 and then measure expression of GOLGA4. Does this perturbation cause a significant change in GOLGA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 111777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2H, does the expression profile of PNPLA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2H, does the expression profile of PNPLA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 89937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TPRKB, does the expression profile of OARD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TPRKB, does the expression profile of OARD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 18681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of STX8. Does perturbing QARS lead to a significant change in STX8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of STX8. Does perturbing QARS lead to a significant change in STX8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 53394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL15 and then measure expression of PAM. Does this perturbation cause a significant change in PAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL15 and then measure expression of PAM. Does this perturbation cause a significant change in PAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 77222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NRDE2 is perturbed and TRDMT1 expression is quantified. Does this perturbation result in a significant change in TRDMT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NRDE2 is perturbed and TRDMT1 expression is quantified. Does this perturbation result in a significant change in TRDMT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM242 and then measure expression of KLHL7. Does this perturbation cause a significant change in KLHL7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM242 and then measure expression of KLHL7. Does this perturbation cause a significant change in KLHL7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 13796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPOX is perturbed and the expression of GNL1 is measured. Determine whether GNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPOX is perturbed and the expression of GNL1 is measured. Determine whether GNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 26654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YEATS2 and then measure expression of TAX1BP3. Does this perturbation cause a significant change in TAX1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YEATS2 and then measure expression of TAX1BP3. Does this perturbation cause a significant change in TAX1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 118848,"You are a functional genomics specialist. In K562 cells, we perturb PTCD3 and monitor EXOC6B expression. Decide whether this perturbation leads to a significant alteration in EXOC6B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTCD3 and monitor EXOC6B expression. Decide whether this perturbation leads to a significant alteration in EXOC6B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 14321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHD4 and examine the expression of DYSF. Does perturbing CHD4 lead to a significant change in DYSF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHD4 and examine the expression of DYSF. Does perturbing CHD4 lead to a significant change in DYSF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 103086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of TRIM8 is measured. Determine whether TRIM8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of TRIM8 is measured. Determine whether TRIM8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 85437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRSF10, does the expression profile of KLF16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRSF10, does the expression profile of KLF16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KDM2A is perturbed and MTHFD2L expression is measured. Determine whether MTHFD2L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KDM2A is perturbed and MTHFD2L expression is measured. Determine whether MTHFD2L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 103733,You are an expert in regulatory genomics. Consider data from K562 cells in which NUP214 is perturbed and LMO4 expression is observed. Does this perturbation lead to a significant difference in LMO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NUP214 is perturbed and LMO4 expression is observed. Does this perturbation lead to a significant difference in LMO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 20669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLC2 is perturbed and SMG6 expression is measured. Determine whether SMG6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLC2 is perturbed and SMG6 expression is measured. Determine whether SMG6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 50950,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of NFIA is measured. Does this perturbation cause a significant change in NFIA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of NFIA is measured. Does this perturbation cause a significant change in NFIA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 123008,"You are a functional genomics specialist. In K562 cells, we perturb FBXO5 and monitor FAM210B expression. Decide whether this perturbation leads to a significant alteration in FAM210B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FBXO5 and monitor FAM210B expression. Decide whether this perturbation leads to a significant alteration in FAM210B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 106482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2A is perturbed and USP25 expression is quantified. Does this perturbation result in a significant change in USP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2A is perturbed and USP25 expression is quantified. Does this perturbation result in a significant change in USP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 59025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUBP2 is associated with a significant change in TMEM115 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUBP2 is associated with a significant change in TMEM115 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 19708,"You are a functional genomics specialist. In K562 cells, we perturb FAM50A and monitor C8orf33 expression. Decide whether this perturbation leads to a significant alteration in C8orf33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FAM50A and monitor C8orf33 expression. Decide whether this perturbation leads to a significant alteration in C8orf33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 19167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UPF2, does the expression profile of FAM214B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UPF2, does the expression profile of FAM214B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 37190,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB4 is perturbed and the expression of DMWD is measured. Does this perturbation cause a significant change in DMWD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB4 is perturbed and the expression of DMWD is measured. Does this perturbation cause a significant change in DMWD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 15042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAF11 is perturbed and NBPF14 expression is quantified. Does this perturbation result in a significant change in NBPF14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAF11 is perturbed and NBPF14 expression is quantified. Does this perturbation result in a significant change in NBPF14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 39090,"You are an expert in single-cell biology and functional genomics. In K562 cells, LAS1L is perturbed and the expression of MAPK6 is measured. Does this perturbation cause a significant change in MAPK6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LAS1L is perturbed and the expression of MAPK6 is measured. Does this perturbation cause a significant change in MAPK6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 37763,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL21 is perturbed and PVT1 expression is observed. Does this perturbation lead to a significant difference in PVT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL21 is perturbed and PVT1 expression is observed. Does this perturbation lead to a significant difference in PVT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 58826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF2F2 is perturbed and the expression of ZNF451 is measured. Determine whether ZNF451 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF2F2 is perturbed and the expression of ZNF451 is measured. Determine whether ZNF451 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 91067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPZ, does the expression profile of LRIG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPZ, does the expression profile of LRIG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 46905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHORDC1 is associated with a significant change in SNHG14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHORDC1 is associated with a significant change in SNHG14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 108816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS4 is perturbed and the expression of LTA4H is measured. Determine whether LTA4H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS4 is perturbed and the expression of LTA4H is measured. Determine whether LTA4H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 82378,"You are a functional genomics specialist. In K562 cells, we perturb KANSL2 and monitor MXD4 expression. Decide whether this perturbation leads to a significant alteration in MXD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KANSL2 and monitor MXD4 expression. Decide whether this perturbation leads to a significant alteration in MXD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 58675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in LINC00662 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in LINC00662 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 21870,"You are an expert in single-cell biology and functional genomics. In K562 cells, NISCH is perturbed and the expression of NMRAL1 is measured. Does this perturbation cause a significant change in NMRAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NISCH is perturbed and the expression of NMRAL1 is measured. Does this perturbation cause a significant change in NMRAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 104986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR3D is perturbed and the expression of TIMM50 is measured. Determine whether TIMM50 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR3D is perturbed and the expression of TIMM50 is measured. Determine whether TIMM50 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 57280,"You are an expert in single-cell biology and functional genomics. In K562 cells, ANAPC10 is perturbed and the expression of TIMM8B is measured. Does this perturbation cause a significant change in TIMM8B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ANAPC10 is perturbed and the expression of TIMM8B is measured. Does this perturbation cause a significant change in TIMM8B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 121674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BRCA1 and then measure expression of YME1L1. Does this perturbation cause a significant change in YME1L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BRCA1 and then measure expression of YME1L1. Does this perturbation cause a significant change in YME1L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 43611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP2R3C and examine the expression of KDELR3. Does perturbing PPP2R3C lead to a significant change in KDELR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP2R3C and examine the expression of KDELR3. Does perturbing PPP2R3C lead to a significant change in KDELR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 110393,You are an expert in regulatory genomics. Consider data from K562 cells in which HDAC7 is perturbed and TUSC2 expression is observed. Does this perturbation lead to a significant difference in TUSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HDAC7 is perturbed and TUSC2 expression is observed. Does this perturbation lead to a significant difference in TUSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 71361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PAK1IP1 and examine the expression of SMG9. Does perturbing PAK1IP1 lead to a significant change in SMG9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PAK1IP1 and examine the expression of SMG9. Does perturbing PAK1IP1 lead to a significant change in SMG9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 18472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RTCB is perturbed and ZNF618 expression is quantified. Does this perturbation result in a significant change in ZNF618 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RTCB is perturbed and ZNF618 expression is quantified. Does this perturbation result in a significant change in ZNF618 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZMAT2 is perturbed and YPEL5 expression is quantified. Does this perturbation result in a significant change in YPEL5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZMAT2 is perturbed and YPEL5 expression is quantified. Does this perturbation result in a significant change in YPEL5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 30728,"You are a functional genomics specialist. In K562 cells, we perturb STX18 and monitor TTC17 expression. Decide whether this perturbation leads to a significant alteration in TTC17 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STX18 and monitor TTC17 expression. Decide whether this perturbation leads to a significant alteration in TTC17 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 41822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FNBP4 is perturbed and ZNF395 expression is quantified. Does this perturbation result in a significant change in ZNF395 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FNBP4 is perturbed and ZNF395 expression is quantified. Does this perturbation result in a significant change in ZNF395 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 66251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SKA1 and examine the expression of TRIAP1. Does perturbing SKA1 lead to a significant change in TRIAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SKA1 and examine the expression of TRIAP1. Does perturbing SKA1 lead to a significant change in TRIAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 33519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TADA2B is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TADA2B is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 101923,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and TESK1 expression is observed. Does this perturbation lead to a significant difference in TESK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and TESK1 expression is observed. Does this perturbation lead to a significant difference in TESK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 34112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FAU is perturbed and IGFBP3 expression is quantified. Does this perturbation result in a significant change in IGFBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FAU is perturbed and IGFBP3 expression is quantified. Does this perturbation result in a significant change in IGFBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 7754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBE2M and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBE2M and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 34457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YEATS4, does the expression profile of PLCB4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YEATS4, does the expression profile of PLCB4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 60062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WBP1L is perturbed and ARFRP1 expression is quantified. Does this perturbation result in a significant change in ARFRP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WBP1L is perturbed and ARFRP1 expression is quantified. Does this perturbation result in a significant change in ARFRP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 67317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USP5, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USP5, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 18315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AP2M1 is associated with a significant change in PPARD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AP2M1 is associated with a significant change in PPARD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 108087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INO80, does the expression profile of ACAA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INO80, does the expression profile of ACAA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 107753,You are an expert in regulatory genomics. Consider data from K562 cells in which SKP1 is perturbed and TLE4 expression is observed. Does this perturbation lead to a significant difference in TLE4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SKP1 is perturbed and TLE4 expression is observed. Does this perturbation lead to a significant difference in TLE4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 9877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM199, does the expression profile of PMM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM199, does the expression profile of PMM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 15860,"You are an expert in single-cell biology and functional genomics. In K562 cells, RIOK1 is perturbed and the expression of ELP1 is measured. Does this perturbation cause a significant change in ELP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RIOK1 is perturbed and the expression of ELP1 is measured. Does this perturbation cause a significant change in ELP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 55880,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR74 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR74 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 25483,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and DENND5A expression is observed. Does this perturbation lead to a significant difference in DENND5A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and DENND5A expression is observed. Does this perturbation lead to a significant difference in DENND5A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 22599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL41 is perturbed and PIGG expression is measured. Determine whether PIGG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL41 is perturbed and PIGG expression is measured. Determine whether PIGG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 115799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TPX2 is perturbed and TTC17 expression is measured. Determine whether TTC17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TPX2 is perturbed and TTC17 expression is measured. Determine whether TTC17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 108974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UTP3 and then measure expression of ITCH. Does this perturbation cause a significant change in ITCH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UTP3 and then measure expression of ITCH. Does this perturbation cause a significant change in ITCH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 67045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DYNLRB1 is associated with a significant change in CBL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DYNLRB1 is associated with a significant change in CBL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 54099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRKCA is perturbed and REV1 expression is measured. Determine whether REV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRKCA is perturbed and REV1 expression is measured. Determine whether REV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 88070,"You are an expert in single-cell biology and functional genomics. In K562 cells, UPF1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UPF1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 50278,"You are a functional genomics specialist. In K562 cells, we perturb HUWE1 and monitor OPTN expression. Decide whether this perturbation leads to a significant alteration in OPTN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HUWE1 and monitor OPTN expression. Decide whether this perturbation leads to a significant alteration in OPTN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 74336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CWC22 is perturbed and the expression of RBM22 is measured. Determine whether RBM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CWC22 is perturbed and the expression of RBM22 is measured. Determine whether RBM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 117252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS10 is perturbed and PLEKHB2 expression is quantified. Does this perturbation result in a significant change in PLEKHB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS10 is perturbed and PLEKHB2 expression is quantified. Does this perturbation result in a significant change in PLEKHB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 120891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABT1 and examine the expression of NPHP3. Does perturbing ABT1 lead to a significant change in NPHP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABT1 and examine the expression of NPHP3. Does perturbing ABT1 lead to a significant change in NPHP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 104453,You are an expert in regulatory genomics. Consider data from K562 cells in which DDX41 is perturbed and ARL8A expression is observed. Does this perturbation lead to a significant difference in ARL8A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDX41 is perturbed and ARL8A expression is observed. Does this perturbation lead to a significant difference in ARL8A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 67643,You are an expert in regulatory genomics. Consider data from K562 cells in which CXXC1 is perturbed and AP4E1 expression is observed. Does this perturbation lead to a significant difference in AP4E1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CXXC1 is perturbed and AP4E1 expression is observed. Does this perturbation lead to a significant difference in AP4E1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 53292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP6V1H is perturbed and BRMS1 expression is quantified. Does this perturbation result in a significant change in BRMS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP6V1H is perturbed and BRMS1 expression is quantified. Does this perturbation result in a significant change in BRMS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 96048,"You are a functional genomics specialist. In K562 cells, we perturb AP2A1 and monitor CHD2 expression. Decide whether this perturbation leads to a significant alteration in CHD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AP2A1 and monitor CHD2 expression. Decide whether this perturbation leads to a significant alteration in CHD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 61394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GET3 and then measure expression of SEC24D. Does this perturbation cause a significant change in SEC24D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GET3 and then measure expression of SEC24D. Does this perturbation cause a significant change in SEC24D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 58289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2H3 is perturbed and MPV17 expression is measured. Determine whether MPV17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2H3 is perturbed and MPV17 expression is measured. Determine whether MPV17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAA20 and examine the expression of CDK6. Does perturbing NAA20 lead to a significant change in CDK6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAA20 and examine the expression of CDK6. Does perturbing NAA20 lead to a significant change in CDK6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 60139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SUPV3L1 is perturbed and PDPR expression is measured. Determine whether PDPR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SUPV3L1 is perturbed and PDPR expression is measured. Determine whether PDPR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 94420,"You are an expert in single-cell biology and functional genomics. In K562 cells, PEF1 is perturbed and the expression of PSMD8 is measured. Does this perturbation cause a significant change in PSMD8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PEF1 is perturbed and the expression of PSMD8 is measured. Does this perturbation cause a significant change in PSMD8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 65949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ANKRD11 is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ANKRD11 is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 10177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IMPDH2, does the expression profile of GJC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IMPDH2, does the expression profile of GJC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 20495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KPNB1 is associated with a significant change in BLOC1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KPNB1 is associated with a significant change in BLOC1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 93895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRD8 is associated with a significant change in GYS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRD8 is associated with a significant change in GYS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 84721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb URI1 and examine the expression of CCDC127. Does perturbing URI1 lead to a significant change in CCDC127 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb URI1 and examine the expression of CCDC127. Does perturbing URI1 lead to a significant change in CCDC127 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 18813,You are an expert in regulatory genomics. Consider data from K562 cells in which NUP85 is perturbed and XPC expression is observed. Does this perturbation lead to a significant difference in XPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NUP85 is perturbed and XPC expression is observed. Does this perturbation lead to a significant difference in XPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 43916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TNRC6A is perturbed and the expression of ZMAT5 is measured. Determine whether ZMAT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TNRC6A is perturbed and the expression of ZMAT5 is measured. Determine whether ZMAT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 22019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPH1 is perturbed and BPTF expression is measured. Determine whether BPTF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPH1 is perturbed and BPTF expression is measured. Determine whether BPTF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 89576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAK16 is perturbed and the expression of ATG101 is measured. Determine whether ATG101 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAK16 is perturbed and the expression of ATG101 is measured. Determine whether ATG101 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 69845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAF6 is associated with a significant change in SPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAF6 is associated with a significant change in SPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 27505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2F is associated with a significant change in KDELR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2F is associated with a significant change in KDELR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 33767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL49, does the expression profile of ITPRIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL49, does the expression profile of ITPRIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 105219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1F is perturbed and MID1 expression is measured. Determine whether MID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1F is perturbed and MID1 expression is measured. Determine whether MID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 86622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BRIX1 is perturbed and GPT2 expression is quantified. Does this perturbation result in a significant change in GPT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BRIX1 is perturbed and GPT2 expression is quantified. Does this perturbation result in a significant change in GPT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 76545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MBD3 is associated with a significant change in NEIL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MBD3 is associated with a significant change in NEIL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 107134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPAIN and then measure expression of KLF7. Does this perturbation cause a significant change in KLF7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPAIN and then measure expression of KLF7. Does this perturbation cause a significant change in KLF7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 65027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP14, does the expression profile of ATXN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP14, does the expression profile of ATXN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 53726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RSL24D1 is perturbed and the expression of PSMB1 is measured. Determine whether PSMB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RSL24D1 is perturbed and the expression of PSMB1 is measured. Determine whether PSMB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 31745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR33 is associated with a significant change in HRAS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR33 is associated with a significant change in HRAS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 92518,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor SLC36A4 expression. Decide whether this perturbation leads to a significant alteration in SLC36A4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor SLC36A4 expression. Decide whether this perturbation leads to a significant alteration in SLC36A4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 73900,"You are an expert in single-cell biology and functional genomics. In K562 cells, TERF1 is perturbed and the expression of CHST14 is measured. Does this perturbation cause a significant change in CHST14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TERF1 is perturbed and the expression of CHST14 is measured. Does this perturbation cause a significant change in CHST14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 31319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RFT1 is perturbed and DBNDD2 expression is measured. Determine whether DBNDD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RFT1 is perturbed and DBNDD2 expression is measured. Determine whether DBNDD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 45254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of C7orf26. Does this perturbation cause a significant change in C7orf26 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of C7orf26. Does this perturbation cause a significant change in C7orf26 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 96937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCAPG2, does the expression profile of RNF139 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCAPG2, does the expression profile of RNF139 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 77858,"You are a functional genomics specialist. In K562 cells, we perturb BUB1B and monitor PKM expression. Decide whether this perturbation leads to a significant alteration in PKM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BUB1B and monitor PKM expression. Decide whether this perturbation leads to a significant alteration in PKM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 23069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHTOP is perturbed and MIR4458HG expression is measured. Determine whether MIR4458HG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHTOP is perturbed and MIR4458HG expression is measured. Determine whether MIR4458HG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 42997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAF2, does the expression profile of PRIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAF2, does the expression profile of PRIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 33984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TEFM and then measure expression of MDK. Does this perturbation cause a significant change in MDK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TEFM and then measure expression of MDK. Does this perturbation cause a significant change in MDK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 102335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF787 is associated with a significant change in PLAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF787 is associated with a significant change in PLAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 53697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RSL24D1, does the expression profile of PAPPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RSL24D1, does the expression profile of PAPPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 84523,You are an expert in regulatory genomics. Consider data from K562 cells in which COA5 is perturbed and BLOC1S5 expression is observed. Does this perturbation lead to a significant difference in BLOC1S5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COA5 is perturbed and BLOC1S5 expression is observed. Does this perturbation lead to a significant difference in BLOC1S5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 84168,"You are a functional genomics specialist. In K562 cells, we perturb MRPL22 and monitor C7orf26 expression. Decide whether this perturbation leads to a significant alteration in C7orf26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL22 and monitor C7orf26 expression. Decide whether this perturbation leads to a significant alteration in C7orf26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 56539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC10 is perturbed and IFI27L2 expression is measured. Determine whether IFI27L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC10 is perturbed and IFI27L2 expression is measured. Determine whether IFI27L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 80642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RGP1 is perturbed and MPC1 expression is quantified. Does this perturbation result in a significant change in MPC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RGP1 is perturbed and MPC1 expression is quantified. Does this perturbation result in a significant change in MPC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 63222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMNDC1 is perturbed and PLEKHG3 expression is quantified. Does this perturbation result in a significant change in PLEKHG3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMNDC1 is perturbed and PLEKHG3 expression is quantified. Does this perturbation result in a significant change in PLEKHG3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 42616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP6V0C is perturbed and the expression of RNF139 is measured. Determine whether RNF139 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP6V0C is perturbed and the expression of RNF139 is measured. Determine whether RNF139 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 106813,You are an expert in regulatory genomics. Consider data from K562 cells in which RBM19 is perturbed and RTCA expression is observed. Does this perturbation lead to a significant difference in RTCA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RBM19 is perturbed and RTCA expression is observed. Does this perturbation lead to a significant difference in RTCA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX46 is perturbed and PNRC1 expression is measured. Determine whether PNRC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX46 is perturbed and PNRC1 expression is measured. Determine whether PNRC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 122066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF10 is perturbed and the expression of SPTLC1 is measured. Determine whether SPTLC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF10 is perturbed and the expression of SPTLC1 is measured. Determine whether SPTLC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 105650,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPB is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPB is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 42553,You are an expert in regulatory genomics. Consider data from K562 cells in which NUTF2 is perturbed and MARCH3 expression is observed. Does this perturbation lead to a significant difference in MARCH3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NUTF2 is perturbed and MARCH3 expression is observed. Does this perturbation lead to a significant difference in MARCH3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 104040,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPIH is perturbed and the expression of DNAJB4 is measured. Does this perturbation cause a significant change in DNAJB4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPIH is perturbed and the expression of DNAJB4 is measured. Does this perturbation cause a significant change in DNAJB4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 91000,"You are an expert in single-cell biology and functional genomics. In K562 cells, HMGCR is perturbed and the expression of NKX2-5 is measured. Does this perturbation cause a significant change in NKX2-5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HMGCR is perturbed and the expression of NKX2-5 is measured. Does this perturbation cause a significant change in NKX2-5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 46468,"You are a functional genomics specialist. In K562 cells, we perturb RSL1D1 and monitor TMEM41A expression. Decide whether this perturbation leads to a significant alteration in TMEM41A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RSL1D1 and monitor TMEM41A expression. Decide whether this perturbation leads to a significant alteration in TMEM41A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 85885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TUBA1C is associated with a significant change in OTUD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TUBA1C is associated with a significant change in OTUD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 102210,"You are an expert in single-cell biology and functional genomics. In K562 cells, LRR1 is perturbed and the expression of MFHAS1 is measured. Does this perturbation cause a significant change in MFHAS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LRR1 is perturbed and the expression of MFHAS1 is measured. Does this perturbation cause a significant change in MFHAS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 77706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBE2I is perturbed and the expression of NIPSNAP1 is measured. Determine whether NIPSNAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBE2I is perturbed and the expression of NIPSNAP1 is measured. Determine whether NIPSNAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 117309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRKRA is perturbed and ENTPD7 expression is measured. Determine whether ENTPD7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRKRA is perturbed and ENTPD7 expression is measured. Determine whether ENTPD7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 90128,"You are a functional genomics specialist. In K562 cells, we perturb NDUFB4 and monitor CA9 expression. Decide whether this perturbation leads to a significant alteration in CA9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NDUFB4 and monitor CA9 expression. Decide whether this perturbation leads to a significant alteration in CA9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 88008,"You are a functional genomics specialist. In K562 cells, we perturb AFG3L2 and monitor ZYX expression. Decide whether this perturbation leads to a significant alteration in ZYX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AFG3L2 and monitor ZYX expression. Decide whether this perturbation leads to a significant alteration in ZYX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 116141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNC1I2 and examine the expression of DDX60L. Does perturbing DYNC1I2 lead to a significant change in DDX60L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNC1I2 and examine the expression of DDX60L. Does perturbing DYNC1I2 lead to a significant change in DDX60L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCTN5 is perturbed and the expression of BIRC6 is measured. Determine whether BIRC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCTN5 is perturbed and the expression of BIRC6 is measured. Determine whether BIRC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 71860,"You are an expert in single-cell biology and functional genomics. In K562 cells, BRK1 is perturbed and the expression of ZNF280D is measured. Does this perturbation cause a significant change in ZNF280D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BRK1 is perturbed and the expression of ZNF280D is measured. Does this perturbation cause a significant change in ZNF280D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 84968,"You are a functional genomics specialist. In K562 cells, we perturb RPS20 and monitor ATP6V1G1 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1G1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RPS20 and monitor ATP6V1G1 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1G1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 27768,"You are a functional genomics specialist. In K562 cells, we perturb QRSL1 and monitor AGO3 expression. Decide whether this perturbation leads to a significant alteration in AGO3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb QRSL1 and monitor AGO3 expression. Decide whether this perturbation leads to a significant alteration in AGO3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 36572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUD31 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUD31 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 91184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PFDN2 and then measure expression of UQCC1. Does this perturbation cause a significant change in UQCC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PFDN2 and then measure expression of UQCC1. Does this perturbation cause a significant change in UQCC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 58545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPA is associated with a significant change in SETD7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPA is associated with a significant change in SETD7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 53287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1H, does the expression profile of GBA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1H, does the expression profile of GBA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 44325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YPEL5 is associated with a significant change in SIRPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YPEL5 is associated with a significant change in SIRPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 121251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR1D and examine the expression of SPOCK1. Does perturbing POLR1D lead to a significant change in SPOCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR1D and examine the expression of SPOCK1. Does perturbing POLR1D lead to a significant change in SPOCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 100928,"You are a functional genomics specialist. In K562 cells, we perturb RNF168 and monitor NOVA1 expression. Decide whether this perturbation leads to a significant alteration in NOVA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RNF168 and monitor NOVA1 expression. Decide whether this perturbation leads to a significant alteration in NOVA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 79326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED8 is perturbed and the expression of TPRG1L is measured. Determine whether TPRG1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED8 is perturbed and the expression of TPRG1L is measured. Determine whether TPRG1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 98651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GPN2 and examine the expression of TNS1. Does perturbing GPN2 lead to a significant change in TNS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GPN2 and examine the expression of TNS1. Does perturbing GPN2 lead to a significant change in TNS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 50091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ORC1 and examine the expression of LRP10. Does perturbing ORC1 lead to a significant change in LRP10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ORC1 and examine the expression of LRP10. Does perturbing ORC1 lead to a significant change in LRP10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IK is associated with a significant change in PLK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IK is associated with a significant change in PLK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 95891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAX and examine the expression of PTPRF. Does perturbing MAX lead to a significant change in PTPRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAX and examine the expression of PTPRF. Does perturbing MAX lead to a significant change in PTPRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 9111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUFIP1 and examine the expression of ADD1. Does perturbing NUFIP1 lead to a significant change in ADD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUFIP1 and examine the expression of ADD1. Does perturbing NUFIP1 lead to a significant change in ADD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 80784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL3 and then measure expression of STRN4. Does this perturbation cause a significant change in STRN4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL3 and then measure expression of STRN4. Does this perturbation cause a significant change in STRN4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 91030,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPZ is perturbed and the expression of PCDH10 is measured. Does this perturbation cause a significant change in PCDH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPZ is perturbed and the expression of PCDH10 is measured. Does this perturbation cause a significant change in PCDH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 45751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNRNPR and examine the expression of CIR1. Does perturbing HNRNPR lead to a significant change in CIR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNRNPR and examine the expression of CIR1. Does perturbing HNRNPR lead to a significant change in CIR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 26750,"You are an expert in single-cell biology and functional genomics. In K562 cells, PHB is perturbed and the expression of PCSK1N is measured. Does this perturbation cause a significant change in PCSK1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PHB is perturbed and the expression of PCSK1N is measured. Does this perturbation cause a significant change in PCSK1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 38694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF1 and then measure expression of NDUFB4. Does this perturbation cause a significant change in NDUFB4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF1 and then measure expression of NDUFB4. Does this perturbation cause a significant change in NDUFB4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 16652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS16 is perturbed and GCFC2 expression is quantified. Does this perturbation result in a significant change in GCFC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS16 is perturbed and GCFC2 expression is quantified. Does this perturbation result in a significant change in GCFC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRNT1 is perturbed and FBN2 expression is measured. Determine whether FBN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRNT1 is perturbed and FBN2 expression is measured. Determine whether FBN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 34353,You are an expert in regulatory genomics. Consider data from K562 cells in which LEO1 is perturbed and FBXO32 expression is observed. Does this perturbation lead to a significant difference in FBXO32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LEO1 is perturbed and FBXO32 expression is observed. Does this perturbation lead to a significant difference in FBXO32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 57379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RTRAF is perturbed and FAM210B expression is measured. Determine whether FAM210B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RTRAF is perturbed and FAM210B expression is measured. Determine whether FAM210B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 110338,"You are a functional genomics specialist. In K562 cells, we perturb NUMA1 and monitor DTWD1 expression. Decide whether this perturbation leads to a significant alteration in DTWD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NUMA1 and monitor DTWD1 expression. Decide whether this perturbation leads to a significant alteration in DTWD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 24157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM6, does the expression profile of ERGIC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM6, does the expression profile of ERGIC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 57097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBX1, does the expression profile of SRD5A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBX1, does the expression profile of SRD5A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 89840,"You are an expert in single-cell biology and functional genomics. In K562 cells, TUBGCP3 is perturbed and the expression of SETDB1 is measured. Does this perturbation cause a significant change in SETDB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TUBGCP3 is perturbed and the expression of SETDB1 is measured. Does this perturbation cause a significant change in SETDB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 94963,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPD1 is perturbed and MIRLET7BHG expression is observed. Does this perturbation lead to a significant difference in MIRLET7BHG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPD1 is perturbed and MIRLET7BHG expression is observed. Does this perturbation lead to a significant difference in MIRLET7BHG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 73070,"You are an expert in single-cell biology and functional genomics. In K562 cells, SIN3A is perturbed and the expression of ENTPD7 is measured. Does this perturbation cause a significant change in ENTPD7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SIN3A is perturbed and the expression of ENTPD7 is measured. Does this perturbation cause a significant change in ENTPD7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1283,You are an expert in regulatory genomics. Consider data from K562 cells in which TFAM is perturbed and VPS53 expression is observed. Does this perturbation lead to a significant difference in VPS53 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TFAM is perturbed and VPS53 expression is observed. Does this perturbation lead to a significant difference in VPS53 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 63065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STX5 is associated with a significant change in SLC25A28 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STX5 is associated with a significant change in SLC25A28 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 36591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BUD31 and examine the expression of PDCD7. Does perturbing BUD31 lead to a significant change in PDCD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BUD31 and examine the expression of PDCD7. Does perturbing BUD31 lead to a significant change in PDCD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 10715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NSUN4 is associated with a significant change in VPS13D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NSUN4 is associated with a significant change in VPS13D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 89851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBGCP3 and examine the expression of RAB11FIP2. Does perturbing TUBGCP3 lead to a significant change in RAB11FIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBGCP3 and examine the expression of RAB11FIP2. Does perturbing TUBGCP3 lead to a significant change in RAB11FIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 43480,"You are an expert in single-cell biology and functional genomics. In K562 cells, JAZF1 is perturbed and the expression of CBLL1 is measured. Does this perturbation cause a significant change in CBLL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, JAZF1 is perturbed and the expression of CBLL1 is measured. Does this perturbation cause a significant change in CBLL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 107506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CD3EAP is perturbed and the expression of AP3S1 is measured. Determine whether AP3S1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CD3EAP is perturbed and the expression of AP3S1 is measured. Determine whether AP3S1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 95280,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 92161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of TIMP1. Does perturbing NVL lead to a significant change in TIMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of TIMP1. Does perturbing NVL lead to a significant change in TIMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 102127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HAUS1, does the expression profile of PRKAG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HAUS1, does the expression profile of PRKAG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 78316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of SAV1 is measured. Determine whether SAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of SAV1 is measured. Determine whether SAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 95270,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of TIMM22 is measured. Does this perturbation cause a significant change in TIMM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of TIMM22 is measured. Does this perturbation cause a significant change in TIMM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 25840,"You are an expert in single-cell biology and functional genomics. In K562 cells, F8A1 is perturbed and the expression of SLC35E3 is measured. Does this perturbation cause a significant change in SLC35E3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, F8A1 is perturbed and the expression of SLC35E3 is measured. Does this perturbation cause a significant change in SLC35E3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 123160,"You are an expert in single-cell biology and functional genomics. In K562 cells, MED21 is perturbed and the expression of UBL7 is measured. Does this perturbation cause a significant change in UBL7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MED21 is perturbed and the expression of UBL7 is measured. Does this perturbation cause a significant change in UBL7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 7074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL18A and then measure expression of COA5. Does this perturbation cause a significant change in COA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL18A and then measure expression of COA5. Does this perturbation cause a significant change in COA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 98714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RRP7A and then measure expression of PLK2. Does this perturbation cause a significant change in PLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RRP7A and then measure expression of PLK2. Does this perturbation cause a significant change in PLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 9679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1G1 is perturbed and LGR4 expression is measured. Determine whether LGR4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1G1 is perturbed and LGR4 expression is measured. Determine whether LGR4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 111926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPSF4 is perturbed and the expression of VCPIP1 is measured. Determine whether VCPIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPSF4 is perturbed and the expression of VCPIP1 is measured. Determine whether VCPIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 23704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPIL2 and then measure expression of POLR3D. Does this perturbation cause a significant change in POLR3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPIL2 and then measure expression of POLR3D. Does this perturbation cause a significant change in POLR3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 22703,You are an expert in regulatory genomics. Consider data from K562 cells in which SS18L2 is perturbed and UTP25 expression is observed. Does this perturbation lead to a significant difference in UTP25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SS18L2 is perturbed and UTP25 expression is observed. Does this perturbation lead to a significant difference in UTP25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 34680,"You are an expert in single-cell biology and functional genomics. In K562 cells, USP10 is perturbed and the expression of NABP2 is measured. Does this perturbation cause a significant change in NABP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, USP10 is perturbed and the expression of NABP2 is measured. Does this perturbation cause a significant change in NABP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 48689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PXN is perturbed and DTD2 expression is measured. Determine whether DTD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PXN is perturbed and DTD2 expression is measured. Determine whether DTD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 18299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AP2M1 is perturbed and EXOSC4 expression is measured. Determine whether EXOSC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AP2M1 is perturbed and EXOSC4 expression is measured. Determine whether EXOSC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 103519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOP3A is perturbed and DSTYK expression is measured. Determine whether DSTYK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOP3A is perturbed and DSTYK expression is measured. Determine whether DSTYK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 112468,"You are a functional genomics specialist. In K562 cells, we perturb MSL1 and monitor ATG9A expression. Decide whether this perturbation leads to a significant alteration in ATG9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MSL1 and monitor ATG9A expression. Decide whether this perturbation leads to a significant alteration in ATG9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 120654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CTR9 and then measure expression of PHLDA3. Does this perturbation cause a significant change in PHLDA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CTR9 and then measure expression of PHLDA3. Does this perturbation cause a significant change in PHLDA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 93178,"You are a functional genomics specialist. In K562 cells, we perturb LSM7 and monitor SCAMP2 expression. Decide whether this perturbation leads to a significant alteration in SCAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LSM7 and monitor SCAMP2 expression. Decide whether this perturbation leads to a significant alteration in SCAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 86613,You are an expert in regulatory genomics. Consider data from K562 cells in which BRIX1 is perturbed and RPL9 expression is observed. Does this perturbation lead to a significant difference in RPL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BRIX1 is perturbed and RPL9 expression is observed. Does this perturbation lead to a significant difference in RPL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 19866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUB1 is perturbed and the expression of IMMT is measured. Determine whether IMMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUB1 is perturbed and the expression of IMMT is measured. Determine whether IMMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 31157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTDP1, does the expression profile of ZBTB44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTDP1, does the expression profile of ZBTB44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 95751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRD2 and examine the expression of MAB21L2. Does perturbing BRD2 lead to a significant change in MAB21L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRD2 and examine the expression of MAB21L2. Does perturbing BRD2 lead to a significant change in MAB21L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 121719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRCA1 is perturbed and AL627171.2 expression is measured. Determine whether AL627171.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRCA1 is perturbed and AL627171.2 expression is measured. Determine whether AL627171.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6303,You are an expert in regulatory genomics. Consider data from K562 cells in which JMJD6 is perturbed and FRMD6-AS1 expression is observed. Does this perturbation lead to a significant difference in FRMD6-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which JMJD6 is perturbed and FRMD6-AS1 expression is observed. Does this perturbation lead to a significant difference in FRMD6-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 115444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NSRP1 and then measure expression of SERINC1. Does this perturbation cause a significant change in SERINC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NSRP1 and then measure expression of SERINC1. Does this perturbation cause a significant change in SERINC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 59709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX54 is perturbed and RANBP9 expression is measured. Determine whether RANBP9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX54 is perturbed and RANBP9 expression is measured. Determine whether RANBP9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 76953,You are an expert in regulatory genomics. Consider data from K562 cells in which PPP4R2 is perturbed and ZNF433-AS1 expression is observed. Does this perturbation lead to a significant difference in ZNF433-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PPP4R2 is perturbed and ZNF433-AS1 expression is observed. Does this perturbation lead to a significant difference in ZNF433-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 121695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRCA1 is associated with a significant change in WASHC2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRCA1 is associated with a significant change in WASHC2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 97633,You are an expert in regulatory genomics. Consider data from K562 cells in which DHX15 is perturbed and SLC16A2 expression is observed. Does this perturbation lead to a significant difference in SLC16A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DHX15 is perturbed and SLC16A2 expression is observed. Does this perturbation lead to a significant difference in SLC16A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 111658,"You are a functional genomics specialist. In K562 cells, we perturb PDAP1 and monitor ADAR expression. Decide whether this perturbation leads to a significant alteration in ADAR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PDAP1 and monitor ADAR expression. Decide whether this perturbation leads to a significant alteration in ADAR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 113136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SKA3 is perturbed and the expression of ROBO1 is measured. Determine whether ROBO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SKA3 is perturbed and the expression of ROBO1 is measured. Determine whether ROBO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 100787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC23, does the expression profile of RSRP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC23, does the expression profile of RSRP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 107579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPD2 is perturbed and FAS expression is measured. Determine whether FAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPD2 is perturbed and FAS expression is measured. Determine whether FAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 48117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS12, does the expression profile of P4HA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS12, does the expression profile of P4HA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 87878,"You are a functional genomics specialist. In K562 cells, we perturb RPS29 and monitor CAMK1D expression. Decide whether this perturbation leads to a significant alteration in CAMK1D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RPS29 and monitor CAMK1D expression. Decide whether this perturbation leads to a significant alteration in CAMK1D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 113264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCNH and then measure expression of ALDH2. Does this perturbation cause a significant change in ALDH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCNH and then measure expression of ALDH2. Does this perturbation cause a significant change in ALDH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 64176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPP14 is perturbed and the expression of ERCC1 is measured. Determine whether ERCC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPP14 is perturbed and the expression of ERCC1 is measured. Determine whether ERCC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 62663,You are an expert in regulatory genomics. Consider data from K562 cells in which TAF5 is perturbed and ACO1 expression is observed. Does this perturbation lead to a significant difference in ACO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TAF5 is perturbed and ACO1 expression is observed. Does this perturbation lead to a significant difference in ACO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 63215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMNDC1 is associated with a significant change in LPIN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMNDC1 is associated with a significant change in LPIN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 99201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSG1 and examine the expression of GNS. Does perturbing LSG1 lead to a significant change in GNS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSG1 and examine the expression of GNS. Does perturbing LSG1 lead to a significant change in GNS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 9357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NRBP1, does the expression profile of SURF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NRBP1, does the expression profile of SURF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 21663,You are an expert in regulatory genomics. Consider data from K562 cells in which CSE1L is perturbed and MAFK expression is observed. Does this perturbation lead to a significant difference in MAFK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CSE1L is perturbed and MAFK expression is observed. Does this perturbation lead to a significant difference in MAFK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 116185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UTP6 is associated with a significant change in TMEM8A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UTP6 is associated with a significant change in TMEM8A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 92922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS8 is perturbed and TBC1D2 expression is quantified. Does this perturbation result in a significant change in TBC1D2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS8 is perturbed and TBC1D2 expression is quantified. Does this perturbation result in a significant change in TBC1D2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 23198,"You are a functional genomics specialist. In K562 cells, we perturb SLC2A8 and monitor GSTM3 expression. Decide whether this perturbation leads to a significant alteration in GSTM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC2A8 and monitor GSTM3 expression. Decide whether this perturbation leads to a significant alteration in GSTM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 114759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZRANB2 is perturbed and DSN1 expression is measured. Determine whether DSN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZRANB2 is perturbed and DSN1 expression is measured. Determine whether DSN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 51731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAE1 and examine the expression of F3. Does perturbing NAE1 lead to a significant change in F3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAE1 and examine the expression of F3. Does perturbing NAE1 lead to a significant change in F3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 11252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELOB is perturbed and WASHC3 expression is quantified. Does this perturbation result in a significant change in WASHC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELOB is perturbed and WASHC3 expression is quantified. Does this perturbation result in a significant change in WASHC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 25030,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS2 is perturbed and the expression of SAAL1 is measured. Does this perturbation cause a significant change in SAAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS2 is perturbed and the expression of SAAL1 is measured. Does this perturbation cause a significant change in SAAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 54941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF39 and examine the expression of HEIH. Does perturbing PRPF39 lead to a significant change in HEIH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF39 and examine the expression of HEIH. Does perturbing PRPF39 lead to a significant change in HEIH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 99312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRNP1 is perturbed and PARD3 expression is quantified. Does this perturbation result in a significant change in PARD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRNP1 is perturbed and PARD3 expression is quantified. Does this perturbation result in a significant change in PARD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 115562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOSC8 is perturbed and NCBP2AS2 expression is quantified. Does this perturbation result in a significant change in NCBP2AS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOSC8 is perturbed and NCBP2AS2 expression is quantified. Does this perturbation result in a significant change in NCBP2AS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 97965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CRLS1 is associated with a significant change in ZUP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CRLS1 is associated with a significant change in ZUP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 103016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDK12 is perturbed and the expression of ITGAV is measured. Determine whether ITGAV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDK12 is perturbed and the expression of ITGAV is measured. Determine whether ITGAV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 107470,"You are an expert in single-cell biology and functional genomics. In K562 cells, CD3EAP is perturbed and the expression of RRAS is measured. Does this perturbation cause a significant change in RRAS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CD3EAP is perturbed and the expression of RRAS is measured. Does this perturbation cause a significant change in RRAS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 121320,"You are an expert in single-cell biology and functional genomics. In K562 cells, DR1 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DR1 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 25823,You are an expert in regulatory genomics. Consider data from K562 cells in which POLR1E is perturbed and TMEM199 expression is observed. Does this perturbation lead to a significant difference in TMEM199 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which POLR1E is perturbed and TMEM199 expression is observed. Does this perturbation lead to a significant difference in TMEM199 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 118347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNRPE, does the expression profile of IGF2BP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNRPE, does the expression profile of IGF2BP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 27083,You are an expert in regulatory genomics. Consider data from K562 cells in which THAP11 is perturbed and SF3B2 expression is observed. Does this perturbation lead to a significant difference in SF3B2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which THAP11 is perturbed and SF3B2 expression is observed. Does this perturbation lead to a significant difference in SF3B2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 83075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCTN2 is associated with a significant change in ZNF107 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCTN2 is associated with a significant change in ZNF107 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 46981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAE1 and examine the expression of WDR55. Does perturbing SAE1 lead to a significant change in WDR55 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAE1 and examine the expression of WDR55. Does perturbing SAE1 lead to a significant change in WDR55 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 69244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DYNLL2 and then measure expression of DUSP4. Does this perturbation cause a significant change in DUSP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DYNLL2 and then measure expression of DUSP4. Does this perturbation cause a significant change in DUSP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 59107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS5, does the expression profile of SLC9A7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS5, does the expression profile of SLC9A7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 52352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO7 is perturbed and SERINC3 expression is quantified. Does this perturbation result in a significant change in SERINC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO7 is perturbed and SERINC3 expression is quantified. Does this perturbation result in a significant change in SERINC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 42123,You are an expert in regulatory genomics. Consider data from K562 cells in which BUB3 is perturbed and NANS expression is observed. Does this perturbation lead to a significant difference in NANS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BUB3 is perturbed and NANS expression is observed. Does this perturbation lead to a significant difference in NANS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 70635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNIP1 is associated with a significant change in MED10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNIP1 is associated with a significant change in MED10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 10718,"You are a functional genomics specialist. In K562 cells, we perturb NSUN4 and monitor VPS13D expression. Decide whether this perturbation leads to a significant alteration in VPS13D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NSUN4 and monitor VPS13D expression. Decide whether this perturbation leads to a significant alteration in VPS13D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 15294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RCCD1 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RCCD1 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 22321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SIRT7 and examine the expression of PFDN5. Does perturbing SIRT7 lead to a significant change in PFDN5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SIRT7 and examine the expression of PFDN5. Does perturbing SIRT7 lead to a significant change in PFDN5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 70014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NFATC2IP and then measure expression of PIP4K2A. Does this perturbation cause a significant change in PIP4K2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NFATC2IP and then measure expression of PIP4K2A. Does this perturbation cause a significant change in PIP4K2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 100074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMA16 and then measure expression of FAM214B. Does this perturbation cause a significant change in FAM214B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMA16 and then measure expression of FAM214B. Does this perturbation cause a significant change in FAM214B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 97332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNHIT6 is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNHIT6 is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 105472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RAD51C is perturbed and PAPPA expression is quantified. Does this perturbation result in a significant change in PAPPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RAD51C is perturbed and PAPPA expression is quantified. Does this perturbation result in a significant change in PAPPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 22643,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5PO is perturbed and DENND5B expression is observed. Does this perturbation lead to a significant difference in DENND5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5PO is perturbed and DENND5B expression is observed. Does this perturbation lead to a significant difference in DENND5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 50103,You are an expert in regulatory genomics. Consider data from K562 cells in which ORC1 is perturbed and RCC2 expression is observed. Does this perturbation lead to a significant difference in RCC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ORC1 is perturbed and RCC2 expression is observed. Does this perturbation lead to a significant difference in RCC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 39731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ESF1 and examine the expression of WDR45. Does perturbing ESF1 lead to a significant change in WDR45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ESF1 and examine the expression of WDR45. Does perturbing ESF1 lead to a significant change in WDR45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 19131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLI4 and examine the expression of SDF4. Does perturbing GLI4 lead to a significant change in SDF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLI4 and examine the expression of SDF4. Does perturbing GLI4 lead to a significant change in SDF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 39554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNM1L and then measure expression of DDI2. Does this perturbation cause a significant change in DDI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNM1L and then measure expression of DDI2. Does this perturbation cause a significant change in DDI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 19931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDB1 and examine the expression of ZNF37A. Does perturbing DDB1 lead to a significant change in ZNF37A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDB1 and examine the expression of ZNF37A. Does perturbing DDB1 lead to a significant change in ZNF37A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 43512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JAZF1 is perturbed and IFT74 expression is quantified. Does this perturbation result in a significant change in IFT74 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JAZF1 is perturbed and IFT74 expression is quantified. Does this perturbation result in a significant change in IFT74 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 75366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATF5 is perturbed and the expression of MMUT is measured. Determine whether MMUT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATF5 is perturbed and the expression of MMUT is measured. Determine whether MMUT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 114547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPT16H, does the expression profile of SNRPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPT16H, does the expression profile of SNRPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 100201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DCTN4 and examine the expression of TENT5A. Does perturbing DCTN4 lead to a significant change in TENT5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DCTN4 and examine the expression of TENT5A. Does perturbing DCTN4 lead to a significant change in TENT5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 38567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ROMO1, does the expression profile of ECSIT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ROMO1, does the expression profile of ECSIT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 105913,You are an expert in regulatory genomics. Consider data from K562 cells in which WDR18 is perturbed and BCAS4 expression is observed. Does this perturbation lead to a significant difference in BCAS4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which WDR18 is perturbed and BCAS4 expression is observed. Does this perturbation lead to a significant difference in BCAS4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 109923,You are an expert in regulatory genomics. Consider data from K562 cells in which TRRAP is perturbed and ANXA6 expression is observed. Does this perturbation lead to a significant difference in ANXA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TRRAP is perturbed and ANXA6 expression is observed. Does this perturbation lead to a significant difference in ANXA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 48112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS12 is perturbed and P4HA1 expression is quantified. Does this perturbation result in a significant change in P4HA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS12 is perturbed and P4HA1 expression is quantified. Does this perturbation result in a significant change in P4HA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 48421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR77 and examine the expression of RIDA. Does perturbing WDR77 lead to a significant change in RIDA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR77 and examine the expression of RIDA. Does perturbing WDR77 lead to a significant change in RIDA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 8163,You are an expert in regulatory genomics. Consider data from K562 cells in which SF3A2 is perturbed and PERP expression is observed. Does this perturbation lead to a significant difference in PERP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SF3A2 is perturbed and PERP expression is observed. Does this perturbation lead to a significant difference in PERP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 31642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCUN1D5 is perturbed and TUSC2 expression is quantified. Does this perturbation result in a significant change in TUSC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCUN1D5 is perturbed and TUSC2 expression is quantified. Does this perturbation result in a significant change in TUSC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 116586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF24 is perturbed and the expression of PHACTR4 is measured. Determine whether PHACTR4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF24 is perturbed and the expression of PHACTR4 is measured. Determine whether PHACTR4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 36772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ABHD11 is perturbed and RARRES1 expression is quantified. Does this perturbation result in a significant change in RARRES1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ABHD11 is perturbed and RARRES1 expression is quantified. Does this perturbation result in a significant change in RARRES1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2018,"You are a functional genomics specialist. In K562 cells, we perturb TRNT1 and monitor FBXO25 expression. Decide whether this perturbation leads to a significant alteration in FBXO25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TRNT1 and monitor FBXO25 expression. Decide whether this perturbation leads to a significant alteration in FBXO25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 19778,"You are a functional genomics specialist. In K562 cells, we perturb NDUFA11 and monitor STK32C expression. Decide whether this perturbation leads to a significant alteration in STK32C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NDUFA11 and monitor STK32C expression. Decide whether this perturbation leads to a significant alteration in STK32C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 72771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP2R1A and examine the expression of PBX1. Does perturbing PPP2R1A lead to a significant change in PBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP2R1A and examine the expression of PBX1. Does perturbing PPP2R1A lead to a significant change in PBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 86457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RANBP2, does the expression profile of GGA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RANBP2, does the expression profile of GGA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 67601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COG1 and examine the expression of PNISR. Does perturbing COG1 lead to a significant change in PNISR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COG1 and examine the expression of PNISR. Does perturbing COG1 lead to a significant change in PNISR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 51639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRSF6 is perturbed and KMT2B expression is measured. Determine whether KMT2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRSF6 is perturbed and KMT2B expression is measured. Determine whether KMT2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 105795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX52 is associated with a significant change in EFEMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX52 is associated with a significant change in EFEMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGS1 and examine the expression of SESN2. Does perturbing PGS1 lead to a significant change in SESN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGS1 and examine the expression of SESN2. Does perturbing PGS1 lead to a significant change in SESN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 62710,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6AP1 is perturbed and the expression of PCSK1N is measured. Does this perturbation cause a significant change in PCSK1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6AP1 is perturbed and the expression of PCSK1N is measured. Does this perturbation cause a significant change in PCSK1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 65396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDRG1 is perturbed and the expression of LINC00511 is measured. Determine whether LINC00511 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDRG1 is perturbed and the expression of LINC00511 is measured. Determine whether LINC00511 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 74986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DKC1 is perturbed and the expression of DCAF12 is measured. Determine whether DCAF12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DKC1 is perturbed and the expression of DCAF12 is measured. Determine whether DCAF12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 57726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCNM1 is perturbed and the expression of C12orf4 is measured. Determine whether C12orf4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCNM1 is perturbed and the expression of C12orf4 is measured. Determine whether C12orf4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 54898,"You are a functional genomics specialist. In K562 cells, we perturb MNAT1 and monitor FILIP1L expression. Decide whether this perturbation leads to a significant alteration in FILIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MNAT1 and monitor FILIP1L expression. Decide whether this perturbation leads to a significant alteration in FILIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 101542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBM8A is perturbed and Z95331.1 expression is quantified. Does this perturbation result in a significant change in Z95331.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBM8A is perturbed and Z95331.1 expression is quantified. Does this perturbation result in a significant change in Z95331.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 83375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TRMT6 is associated with a significant change in GSTZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TRMT6 is associated with a significant change in GSTZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX59 is perturbed and BSDC1 expression is quantified. Does this perturbation result in a significant change in BSDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX59 is perturbed and BSDC1 expression is quantified. Does this perturbation result in a significant change in BSDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 108289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHEK1 is perturbed and PEX26 expression is measured. Determine whether PEX26 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHEK1 is perturbed and PEX26 expression is measured. Determine whether PEX26 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IK, does the expression profile of AC005261.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IK, does the expression profile of AC005261.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 47410,"You are an expert in single-cell biology and functional genomics. In K562 cells, ING3 is perturbed and the expression of LAMC1 is measured. Does this perturbation cause a significant change in LAMC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ING3 is perturbed and the expression of LAMC1 is measured. Does this perturbation cause a significant change in LAMC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 75818,"You are a functional genomics specialist. In K562 cells, we perturb LRPPRC and monitor UQCRC1 expression. Decide whether this perturbation leads to a significant alteration in UQCRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb LRPPRC and monitor UQCRC1 expression. Decide whether this perturbation leads to a significant alteration in UQCRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 105382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, USF2 is perturbed and AGPS expression is quantified. Does this perturbation result in a significant change in AGPS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, USF2 is perturbed and AGPS expression is quantified. Does this perturbation result in a significant change in AGPS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 20710,"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of ALS2 is measured. Does this perturbation cause a significant change in ALS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of ALS2 is measured. Does this perturbation cause a significant change in ALS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 85347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNF20, does the expression profile of ZMYND19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNF20, does the expression profile of ZMYND19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 58021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KTI12 and examine the expression of ECHDC2. Does perturbing KTI12 lead to a significant change in ECHDC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KTI12 and examine the expression of ECHDC2. Does perturbing KTI12 lead to a significant change in ECHDC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 10129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP2CB is perturbed and IGBP1 expression is measured. Determine whether IGBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP2CB is perturbed and IGBP1 expression is measured. Determine whether IGBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 29983,You are an expert in regulatory genomics. Consider data from K562 cells in which NELFB is perturbed and ATP5F1A expression is observed. Does this perturbation lead to a significant difference in ATP5F1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NELFB is perturbed and ATP5F1A expression is observed. Does this perturbation lead to a significant difference in ATP5F1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 10328,"You are a functional genomics specialist. In K562 cells, we perturb MRPL34 and monitor OTUD7B expression. Decide whether this perturbation leads to a significant alteration in OTUD7B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL34 and monitor OTUD7B expression. Decide whether this perturbation leads to a significant alteration in OTUD7B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 82905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIS18BP1 is associated with a significant change in UNC119B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIS18BP1 is associated with a significant change in UNC119B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 26394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DPM2 and then measure expression of C16orf58. Does this perturbation cause a significant change in C16orf58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DPM2 and then measure expression of C16orf58. Does this perturbation cause a significant change in C16orf58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 78272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARL4D is perturbed and SOX4 expression is quantified. Does this perturbation result in a significant change in SOX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARL4D is perturbed and SOX4 expression is quantified. Does this perturbation result in a significant change in SOX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 70358,"You are a functional genomics specialist. In K562 cells, we perturb AASDHPPT and monitor DGKA expression. Decide whether this perturbation leads to a significant alteration in DGKA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AASDHPPT and monitor DGKA expression. Decide whether this perturbation leads to a significant alteration in DGKA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 57538,"You are a functional genomics specialist. In K562 cells, we perturb SCD and monitor GNB1 expression. Decide whether this perturbation leads to a significant alteration in GNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SCD and monitor GNB1 expression. Decide whether this perturbation leads to a significant alteration in GNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 103343,You are an expert in regulatory genomics. Consider data from K562 cells in which SHOC2 is perturbed and AC005670.3 expression is observed. Does this perturbation lead to a significant difference in AC005670.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SHOC2 is perturbed and AC005670.3 expression is observed. Does this perturbation lead to a significant difference in AC005670.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 122810,"You are an expert in single-cell biology and functional genomics. In K562 cells, BARD1 is perturbed and the expression of SEC22B is measured. Does this perturbation cause a significant change in SEC22B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BARD1 is perturbed and the expression of SEC22B is measured. Does this perturbation cause a significant change in SEC22B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 14544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of OPA1. Does this perturbation cause a significant change in OPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of OPA1. Does this perturbation cause a significant change in OPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 17276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP133 is perturbed and the expression of DHRS1 is measured. Determine whether DHRS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP133 is perturbed and the expression of DHRS1 is measured. Determine whether DHRS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 119421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTV1 and examine the expression of CDK12. Does perturbing LTV1 lead to a significant change in CDK12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTV1 and examine the expression of CDK12. Does perturbing LTV1 lead to a significant change in CDK12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 24082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and GOLT1B expression is quantified. Does this perturbation result in a significant change in GOLT1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and GOLT1B expression is quantified. Does this perturbation result in a significant change in GOLT1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 83361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT6 and examine the expression of AC010198.2. Does perturbing TRMT6 lead to a significant change in AC010198.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT6 and examine the expression of AC010198.2. Does perturbing TRMT6 lead to a significant change in AC010198.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 76519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MBD3 is perturbed and PET117 expression is measured. Determine whether PET117 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MBD3 is perturbed and PET117 expression is measured. Determine whether PET117 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 27916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHCHD4 is perturbed and the expression of C6orf120 is measured. Determine whether C6orf120 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHCHD4 is perturbed and the expression of C6orf120 is measured. Determine whether C6orf120 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 24765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCAPH is associated with a significant change in CCPG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCAPH is associated with a significant change in CCPG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 16663,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS16 is perturbed and ARHGEF2 expression is observed. Does this perturbation lead to a significant difference in ARHGEF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS16 is perturbed and ARHGEF2 expression is observed. Does this perturbation lead to a significant difference in ARHGEF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B10 is perturbed and POM121 expression is measured. Determine whether POM121 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B10 is perturbed and POM121 expression is measured. Determine whether POM121 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 99285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK1 is associated with a significant change in ROR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK1 is associated with a significant change in ROR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 50471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOC3 and examine the expression of RPS18. Does perturbing EXOC3 lead to a significant change in RPS18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOC3 and examine the expression of RPS18. Does perturbing EXOC3 lead to a significant change in RPS18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 59932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COTL1 is perturbed and GNB5 expression is quantified. Does this perturbation result in a significant change in GNB5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COTL1 is perturbed and GNB5 expression is quantified. Does this perturbation result in a significant change in GNB5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 78475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS26 is associated with a significant change in SQSTM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS26 is associated with a significant change in SQSTM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 41945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX3X is associated with a significant change in PPA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX3X is associated with a significant change in PPA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 73077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SIN3A, does the expression profile of ENTPD7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SIN3A, does the expression profile of ENTPD7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 78733,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD6 is perturbed and BAG6 expression is observed. Does this perturbation lead to a significant difference in BAG6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD6 is perturbed and BAG6 expression is observed. Does this perturbation lead to a significant difference in BAG6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 37862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PIAS4 is perturbed and FNDC3B expression is quantified. Does this perturbation result in a significant change in FNDC3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PIAS4 is perturbed and FNDC3B expression is quantified. Does this perturbation result in a significant change in FNDC3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 71794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR12 and then measure expression of NACC2. Does this perturbation cause a significant change in NACC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR12 and then measure expression of NACC2. Does this perturbation cause a significant change in NACC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 46368,"You are a functional genomics specialist. In K562 cells, we perturb TUBGCP2 and monitor CYFIP2 expression. Decide whether this perturbation leads to a significant alteration in CYFIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TUBGCP2 and monitor CYFIP2 expression. Decide whether this perturbation leads to a significant alteration in CYFIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 50633,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD9 is perturbed and LINC02802 expression is observed. Does this perturbation lead to a significant difference in LINC02802 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD9 is perturbed and LINC02802 expression is observed. Does this perturbation lead to a significant difference in LINC02802 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 98863,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL13A is perturbed and FLYWCH2 expression is observed. Does this perturbation lead to a significant difference in FLYWCH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RPL13A is perturbed and FLYWCH2 expression is observed. Does this perturbation lead to a significant difference in FLYWCH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 95038,"You are a functional genomics specialist. In K562 cells, we perturb DDX11 and monitor WWC3 expression. Decide whether this perturbation leads to a significant alteration in WWC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDX11 and monitor WWC3 expression. Decide whether this perturbation leads to a significant alteration in WWC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 37544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STRIP1 and then measure expression of KRT18. Does this perturbation cause a significant change in KRT18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STRIP1 and then measure expression of KRT18. Does this perturbation cause a significant change in KRT18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 51338,"You are a functional genomics specialist. In K562 cells, we perturb WDR4 and monitor RGS3 expression. Decide whether this perturbation leads to a significant alteration in RGS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb WDR4 and monitor RGS3 expression. Decide whether this perturbation leads to a significant alteration in RGS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3020,"You are an expert in single-cell biology and functional genomics. In K562 cells, COX10 is perturbed and the expression of POLR3H is measured. Does this perturbation cause a significant change in POLR3H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COX10 is perturbed and the expression of POLR3H is measured. Does this perturbation cause a significant change in POLR3H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 58087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RARS2, does the expression profile of SCNM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RARS2, does the expression profile of SCNM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 75325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AATF is associated with a significant change in AOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AATF is associated with a significant change in AOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 53776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMG6 is perturbed and the expression of APTX is measured. Determine whether APTX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMG6 is perturbed and the expression of APTX is measured. Determine whether APTX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 38151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM12 and examine the expression of COMMD4. Does perturbing LSM12 lead to a significant change in COMMD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM12 and examine the expression of COMMD4. Does perturbing LSM12 lead to a significant change in COMMD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 43333,You are an expert in regulatory genomics. Consider data from K562 cells in which GEMIN6 is perturbed and AGPS expression is observed. Does this perturbation lead to a significant difference in AGPS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GEMIN6 is perturbed and AGPS expression is observed. Does this perturbation lead to a significant difference in AGPS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 81614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ALG1 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ALG1 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 84976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS20 is perturbed and the expression of TNFRSF10D is measured. Determine whether TNFRSF10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS20 is perturbed and the expression of TNFRSF10D is measured. Determine whether TNFRSF10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 57995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KTI12 is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KTI12 is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 54413,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V0B is perturbed and UBR1 expression is observed. Does this perturbation lead to a significant difference in UBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V0B is perturbed and UBR1 expression is observed. Does this perturbation lead to a significant difference in UBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 50958,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor NFIA expression. Decide whether this perturbation leads to a significant alteration in NFIA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor NFIA expression. Decide whether this perturbation leads to a significant alteration in NFIA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 66787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UHRF1, does the expression profile of ESCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UHRF1, does the expression profile of ESCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 37345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBMX is associated with a significant change in IFI27L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBMX is associated with a significant change in IFI27L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 78678,"You are a functional genomics specialist. In K562 cells, we perturb ZCCHC9 and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZCCHC9 and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 10233,You are an expert in regulatory genomics. Consider data from K562 cells in which HECTD1 is perturbed and FNIP2 expression is observed. Does this perturbation lead to a significant difference in FNIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HECTD1 is perturbed and FNIP2 expression is observed. Does this perturbation lead to a significant difference in FNIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 71562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and FUCA1 expression is quantified. Does this perturbation result in a significant change in FUCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and FUCA1 expression is quantified. Does this perturbation result in a significant change in FUCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 45477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX23, does the expression profile of OSBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX23, does the expression profile of OSBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 106757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GINS2, does the expression profile of TTBK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GINS2, does the expression profile of TTBK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 51041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3A and examine the expression of ITGA11. Does perturbing EIF3A lead to a significant change in ITGA11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3A and examine the expression of ITGA11. Does perturbing EIF3A lead to a significant change in ITGA11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 115304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS28 and then measure expression of FKRP. Does this perturbation cause a significant change in FKRP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS28 and then measure expression of FKRP. Does this perturbation cause a significant change in FKRP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 88844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC11 and then measure expression of MAP1A. Does this perturbation cause a significant change in MAP1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC11 and then measure expression of MAP1A. Does this perturbation cause a significant change in MAP1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 24905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP6V1A is associated with a significant change in KPNA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP6V1A is associated with a significant change in KPNA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 10125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPP2CB is associated with a significant change in IGBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPP2CB is associated with a significant change in IGBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 64189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPP14 is perturbed and MAN1A2 expression is measured. Determine whether MAN1A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPP14 is perturbed and MAN1A2 expression is measured. Determine whether MAN1A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 84016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HPS5 is perturbed and the expression of FGF2 is measured. Determine whether FGF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HPS5 is perturbed and the expression of FGF2 is measured. Determine whether FGF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 41566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL38 is perturbed and the expression of OSBPL2 is measured. Determine whether OSBPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL38 is perturbed and the expression of OSBPL2 is measured. Determine whether OSBPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 87211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDFY3 and examine the expression of APOOL. Does perturbing WDFY3 lead to a significant change in APOOL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDFY3 and examine the expression of APOOL. Does perturbing WDFY3 lead to a significant change in APOOL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 108495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ANKLE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ANKLE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 14986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R7 is perturbed and the expression of HLA-B is measured. Determine whether HLA-B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R7 is perturbed and the expression of HLA-B is measured. Determine whether HLA-B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 43841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PKM and examine the expression of PKD1. Does perturbing PKM lead to a significant change in PKD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PKM and examine the expression of PKD1. Does perturbing PKM lead to a significant change in PKD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 47694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUGP1 and then measure expression of NORAD. Does this perturbation cause a significant change in NORAD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUGP1 and then measure expression of NORAD. Does this perturbation cause a significant change in NORAD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 20344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCFD1 and then measure expression of TRAPPC5. Does this perturbation cause a significant change in TRAPPC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCFD1 and then measure expression of TRAPPC5. Does this perturbation cause a significant change in TRAPPC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 76171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTBP1 and examine the expression of ZSCAN30. Does perturbing PTBP1 lead to a significant change in ZSCAN30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTBP1 and examine the expression of ZSCAN30. Does perturbing PTBP1 lead to a significant change in ZSCAN30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 54309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOE1 is perturbed and PKD2 expression is measured. Determine whether PKD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOE1 is perturbed and PKD2 expression is measured. Determine whether PKD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 48385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC5L is associated with a significant change in ACP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC5L is associated with a significant change in ACP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 20992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, URB1 is perturbed and TRIM5 expression is quantified. Does this perturbation result in a significant change in TRIM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, URB1 is perturbed and TRIM5 expression is quantified. Does this perturbation result in a significant change in TRIM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."