[
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of SELENOM. Does perturbing CCT5 lead to a significant change in SELENOM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of SELENOM. Does perturbing CCT5 lead to a significant change in SELENOM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123611
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1F and examine the expression of ZNF32. Does perturbing ATP6V1F lead to a significant change in ZNF32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1F and examine the expression of ZNF32. Does perturbing ATP6V1F lead to a significant change in ZNF32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105191
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNLRB1, does the expression profile of SLC6A6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNLRB1, does the expression profile of SLC6A6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67017
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RNGTT and monitor RNF6 expression. Decide whether this perturbation leads to a significant alteration in RNF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RNGTT and monitor RNF6 expression. Decide whether this perturbation leads to a significant alteration in RNF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103008
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAP1 is perturbed and INPP1 expression is observed. Does this perturbation lead to a significant difference in INPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAP1 is perturbed and INPP1 expression is observed. Does this perturbation lead to a significant difference in INPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73483
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C9orf78 is associated with a significant change in ARL6IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C9orf78 is associated with a significant change in ARL6IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29505
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CYREN is perturbed and HELZ expression is observed. Does this perturbation lead to a significant difference in HELZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CYREN is perturbed and HELZ expression is observed. Does this perturbation lead to a significant difference in HELZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118743
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARFRP1 and examine the expression of SSNA1. Does perturbing ARFRP1 lead to a significant change in SSNA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARFRP1 and examine the expression of SSNA1. Does perturbing ARFRP1 lead to a significant change in SSNA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72151
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM10 is associated with a significant change in REPS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM10 is associated with a significant change in REPS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110505
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL28 is perturbed and MRPL50 expression is observed. Does this perturbation lead to a significant difference in MRPL50 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL28 is perturbed and MRPL50 expression is observed. Does this perturbation lead to a significant difference in MRPL50 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68843
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC1 is perturbed and B4GALT1 expression is measured. Determine whether B4GALT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC1 is perturbed and B4GALT1 expression is measured. Determine whether B4GALT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100809
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP9 is perturbed and THBD expression is observed. Does this perturbation lead to a significant difference in THBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP9 is perturbed and THBD expression is observed. Does this perturbation lead to a significant difference in THBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77453
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC4 is perturbed and BID expression is measured. Determine whether BID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC4 is perturbed and BID expression is measured. Determine whether BID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79889
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PYURF and monitor GADD45A expression. Decide whether this perturbation leads to a significant alteration in GADD45A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PYURF and monitor GADD45A expression. Decide whether this perturbation leads to a significant alteration in GADD45A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64738
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTF2 is perturbed and FAS expression is observed. Does this perturbation lead to a significant difference in FAS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTF2 is perturbed and FAS expression is observed. Does this perturbation lead to a significant difference in FAS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93373
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM5 is perturbed and the expression of ARSK is measured. Does this perturbation cause a significant change in ARSK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM5 is perturbed and the expression of ARSK is measured. Does this perturbation cause a significant change in ARSK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85640
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC6 is associated with a significant change in SHISA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC6 is associated with a significant change in SHISA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1475
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRD8 is perturbed and OS9 expression is measured. Determine whether OS9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRD8 is perturbed and OS9 expression is measured. Determine whether OS9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93909
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX23 is associated with a significant change in PPM1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX23 is associated with a significant change in PPM1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45505
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MKRN1 is perturbed and the expression of PCDH7 is measured. Does this perturbation cause a significant change in PCDH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MKRN1 is perturbed and the expression of PCDH7 is measured. Does this perturbation cause a significant change in PCDH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58170
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHC1 and then measure expression of ZNF205. Does this perturbation cause a significant change in ZNF205 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHC1 and then measure expression of ZNF205. Does this perturbation cause a significant change in ZNF205 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23164
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TOE1 is associated with a significant change in NIPAL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TOE1 is associated with a significant change in NIPAL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54275
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EEFSEC and monitor NREP expression. Decide whether this perturbation leads to a significant alteration in NREP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EEFSEC and monitor NREP expression. Decide whether this perturbation leads to a significant alteration in NREP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86748
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GON4L is perturbed and SELENOM expression is observed. Does this perturbation lead to a significant difference in SELENOM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GON4L is perturbed and SELENOM expression is observed. Does this perturbation lead to a significant difference in SELENOM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64923
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEF1A1 and examine the expression of PDXDC1. Does perturbing EEF1A1 lead to a significant change in PDXDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEF1A1 and examine the expression of PDXDC1. Does perturbing EEF1A1 lead to a significant change in PDXDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69121
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FBXO42 and monitor TNNT1 expression. Decide whether this perturbation leads to a significant alteration in TNNT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FBXO42 and monitor TNNT1 expression. Decide whether this perturbation leads to a significant alteration in TNNT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1158
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLBP is perturbed and MYL9 expression is observed. Does this perturbation lead to a significant difference in MYL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLBP is perturbed and MYL9 expression is observed. Does this perturbation lead to a significant difference in MYL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120953
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GTPBP4 is perturbed and the expression of HEXA is measured. Does this perturbation cause a significant change in HEXA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GTPBP4 is perturbed and the expression of HEXA is measured. Does this perturbation cause a significant change in HEXA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53790
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDCD11 is perturbed and MIEN1 expression is measured. Determine whether MIEN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDCD11 is perturbed and MIEN1 expression is measured. Determine whether MIEN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116469
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFAM is perturbed and the expression of MYH9 is measured. Determine whether MYH9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFAM is perturbed and the expression of MYH9 is measured. Determine whether MYH9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1266
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PMF1 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PMF1 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36083
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDCD6 is perturbed and GSPT2 expression is observed. Does this perturbation lead to a significant difference in GSPT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDCD6 is perturbed and GSPT2 expression is observed. Does this perturbation lead to a significant difference in GSPT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6853
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASF1B is perturbed and RCAN1 expression is quantified. Does this perturbation result in a significant change in RCAN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASF1B is perturbed and RCAN1 expression is quantified. Does this perturbation result in a significant change in RCAN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85412
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UTP18 and then measure expression of BORCS5. Does this perturbation cause a significant change in BORCS5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UTP18 and then measure expression of BORCS5. Does this perturbation cause a significant change in BORCS5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111634
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMG2 and monitor MOSPD1 expression. Decide whether this perturbation leads to a significant alteration in MOSPD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMG2 and monitor MOSPD1 expression. Decide whether this perturbation leads to a significant alteration in MOSPD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82278
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZMAT2 is perturbed and the expression of NEU1 is measured. Does this perturbation cause a significant change in NEU1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZMAT2 is perturbed and the expression of NEU1 is measured. Does this perturbation cause a significant change in NEU1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5150
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3C3 and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3C3 and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73254
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS27 is perturbed and ZIM3 expression is measured. Determine whether ZIM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS27 is perturbed and ZIM3 expression is measured. Determine whether ZIM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99419
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GPN2 is perturbed and TSFM expression is measured. Determine whether TSFM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GPN2 is perturbed and TSFM expression is measured. Determine whether TSFM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98679
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H13 and examine the expression of RNF25. Does perturbing ZC3H13 lead to a significant change in RNF25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H13 and examine the expression of RNF25. Does perturbing ZC3H13 lead to a significant change in RNF25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2581
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GAPDH is perturbed and SMIM10L1 expression is quantified. Does this perturbation result in a significant change in SMIM10L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GAPDH is perturbed and SMIM10L1 expression is quantified. Does this perturbation result in a significant change in SMIM10L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54502
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COMTD1 and monitor GPATCH8 expression. Decide whether this perturbation leads to a significant alteration in GPATCH8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COMTD1 and monitor GPATCH8 expression. Decide whether this perturbation leads to a significant alteration in GPATCH8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45308
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EDC4 is perturbed and IKBIP expression is quantified. Does this perturbation result in a significant change in IKBIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EDC4 is perturbed and IKBIP expression is quantified. Does this perturbation result in a significant change in IKBIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44712
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC42 is associated with a significant change in KYAT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC42 is associated with a significant change in KYAT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86675
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNF8 and examine the expression of TRIM73. Does perturbing SNF8 lead to a significant change in TRIM73 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNF8 and examine the expression of TRIM73. Does perturbing SNF8 lead to a significant change in TRIM73 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72981
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP192 and then measure expression of HHIP-AS1. Does this perturbation cause a significant change in HHIP-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP192 and then measure expression of HHIP-AS1. Does this perturbation cause a significant change in HHIP-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29194
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RMI1 is perturbed and UBE3C expression is measured. Determine whether UBE3C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RMI1 is perturbed and UBE3C expression is measured. Determine whether UBE3C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85579
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCNA and examine the expression of ZSCAN26. Does perturbing PCNA lead to a significant change in ZSCAN26 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PCNA and examine the expression of ZSCAN26. Does perturbing PCNA lead to a significant change in ZSCAN26 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55401
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS9 is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS9 is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34290
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC3 and examine the expression of SEZ6L2. Does perturbing THOC3 lead to a significant change in SEZ6L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC3 and examine the expression of SEZ6L2. Does perturbing THOC3 lead to a significant change in SEZ6L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11221
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GIT2 is perturbed and the expression of GSE1 is measured. Does this perturbation cause a significant change in GSE1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GIT2 is perturbed and the expression of GSE1 is measured. Does this perturbation cause a significant change in GSE1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27150
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SON and monitor STX3 expression. Decide whether this perturbation leads to a significant alteration in STX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SON and monitor STX3 expression. Decide whether this perturbation leads to a significant alteration in STX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29078
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and FARP2 expression is observed. Does this perturbation lead to a significant difference in FARP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and FARP2 expression is observed. Does this perturbation lead to a significant difference in FARP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55853
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SETD5 and examine the expression of WNK3. Does perturbing SETD5 lead to a significant change in WNK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SETD5 and examine the expression of WNK3. Does perturbing SETD5 lead to a significant change in WNK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":331
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CACNB3 and monitor SYVN1 expression. Decide whether this perturbation leads to a significant alteration in SYVN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CACNB3 and monitor SYVN1 expression. Decide whether this perturbation leads to a significant alteration in SYVN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33828
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CWC22 and monitor NCBP2AS2 expression. Decide whether this perturbation leads to a significant alteration in NCBP2AS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CWC22 and monitor NCBP2AS2 expression. Decide whether this perturbation leads to a significant alteration in NCBP2AS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74348
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL18 is perturbed and UBTD1 expression is observed. Does this perturbation lead to a significant difference in UBTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL18 is perturbed and UBTD1 expression is observed. Does this perturbation lead to a significant difference in UBTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82923
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM4 and examine the expression of SERINC2. Does perturbing LSM4 lead to a significant change in SERINC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM4 and examine the expression of SERINC2. Does perturbing LSM4 lead to a significant change in SERINC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30731
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ORC3 is associated with a significant change in SAMD9L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ORC3 is associated with a significant change in SAMD9L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51405
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL51 and monitor SLC6A8 expression. Decide whether this perturbation leads to a significant alteration in SLC6A8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL51 and monitor SLC6A8 expression. Decide whether this perturbation leads to a significant alteration in SLC6A8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106648
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYF2 and then measure expression of IRS2. Does this perturbation cause a significant change in IRS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYF2 and then measure expression of IRS2. Does this perturbation cause a significant change in IRS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24434
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GPS1 is perturbed and the expression of BDNF is measured. Determine whether BDNF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GPS1 is perturbed and the expression of BDNF is measured. Determine whether BDNF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5966
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR3K and then measure expression of DNER. Does this perturbation cause a significant change in DNER expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR3K and then measure expression of DNER. Does this perturbation cause a significant change in DNER expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28414
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2B and examine the expression of EFEMP1. Does perturbing GTF2B lead to a significant change in EFEMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2B and examine the expression of EFEMP1. Does perturbing GTF2B lead to a significant change in EFEMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99891
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DYNLL1 is perturbed and the expression of ZGPAT is measured. Determine whether ZGPAT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DYNLL1 is perturbed and the expression of ZGPAT is measured. Determine whether ZGPAT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94296
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MPG and then measure expression of DLD. Does this perturbation cause a significant change in DLD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MPG and then measure expression of DLD. Does this perturbation cause a significant change in DLD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3854
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMNDC1 is perturbed and SCNM1 expression is quantified. Does this perturbation result in a significant change in SCNM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMNDC1 is perturbed and SCNM1 expression is quantified. Does this perturbation result in a significant change in SCNM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63182
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CMPK1 and then measure expression of GLA. Does this perturbation cause a significant change in GLA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CMPK1 and then measure expression of GLA. Does this perturbation cause a significant change in GLA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13084
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PALB2 is perturbed and TARSL2 expression is quantified. Does this perturbation result in a significant change in TARSL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PALB2 is perturbed and TARSL2 expression is quantified. Does this perturbation result in a significant change in TARSL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30962
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DCAF6 is perturbed and RPL10A expression is observed. Does this perturbation lead to a significant difference in RPL10A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DCAF6 is perturbed and RPL10A expression is observed. Does this perturbation lead to a significant difference in RPL10A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6583
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPIL4 is perturbed and the expression of SH3RF2 is measured. Determine whether SH3RF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPIL4 is perturbed and the expression of SH3RF2 is measured. Determine whether SH3RF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63636
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NARS2 is perturbed and ANKZF1 expression is observed. Does this perturbation lead to a significant difference in ANKZF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NARS2 is perturbed and ANKZF1 expression is observed. Does this perturbation lead to a significant difference in ANKZF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26583
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNTB2 is perturbed and UNC93B1 expression is quantified. Does this perturbation result in a significant change in UNC93B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNTB2 is perturbed and UNC93B1 expression is quantified. Does this perturbation result in a significant change in UNC93B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120582
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYBBP1A and examine the expression of F3. Does perturbing MYBBP1A lead to a significant change in F3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYBBP1A and examine the expression of F3. Does perturbing MYBBP1A lead to a significant change in F3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4481
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121326
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP53RK is perturbed and the expression of WIPI1 is measured. Determine whether WIPI1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP53RK is perturbed and the expression of WIPI1 is measured. Determine whether WIPI1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14716
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNRPD3 and examine the expression of WIPI2. Does perturbing SNRPD3 lead to a significant change in WIPI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNRPD3 and examine the expression of WIPI2. Does perturbing SNRPD3 lead to a significant change in WIPI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24631
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GGPS1 is perturbed and ARFGEF2 expression is quantified. Does this perturbation result in a significant change in ARFGEF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GGPS1 is perturbed and ARFGEF2 expression is quantified. Does this perturbation result in a significant change in ARFGEF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86982
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V1C1 and then measure expression of TM7SF2. Does this perturbation cause a significant change in TM7SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V1C1 and then measure expression of TM7SF2. Does this perturbation cause a significant change in TM7SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118434
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC8 and examine the expression of ZNF148. Does perturbing TRAPPC8 lead to a significant change in ZNF148 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC8 and examine the expression of ZNF148. Does perturbing TRAPPC8 lead to a significant change in ZNF148 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115671
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EP400 and then measure expression of ACO2. Does this perturbation cause a significant change in ACO2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EP400 and then measure expression of ACO2. Does this perturbation cause a significant change in ACO2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88614
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MVD and monitor SPTY2D1 expression. Decide whether this perturbation leads to a significant alteration in SPTY2D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MVD and monitor SPTY2D1 expression. Decide whether this perturbation leads to a significant alteration in SPTY2D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67478
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ACTR3 and monitor FBXO9 expression. Decide whether this perturbation leads to a significant alteration in FBXO9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ACTR3 and monitor FBXO9 expression. Decide whether this perturbation leads to a significant alteration in FBXO9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58888
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMELESS is perturbed and NCBP2 expression is observed. Does this perturbation lead to a significant difference in NCBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMELESS is perturbed and NCBP2 expression is observed. Does this perturbation lead to a significant difference in NCBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121183
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, THAP11 is perturbed and the expression of MEIS2 is measured. Determine whether MEIS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, THAP11 is perturbed and the expression of MEIS2 is measured. Determine whether MEIS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27096
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LAMTOR4 and monitor MCCC1 expression. Decide whether this perturbation leads to a significant alteration in MCCC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LAMTOR4 and monitor MCCC1 expression. Decide whether this perturbation leads to a significant alteration in MCCC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62498
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NELFB and examine the expression of HLA-B. Does perturbing NELFB lead to a significant change in HLA-B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NELFB and examine the expression of HLA-B. Does perturbing NELFB lead to a significant change in HLA-B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29961
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTR1B, does the expression profile of TMEM132A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTR1B, does the expression profile of TMEM132A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66297
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RBBP5 and monitor TRIM24 expression. Decide whether this perturbation leads to a significant alteration in TRIM24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RBBP5 and monitor TRIM24 expression. Decide whether this perturbation leads to a significant alteration in TRIM24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74088
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF236 is perturbed and the expression of FILIP1L is measured. Does this perturbation cause a significant change in FILIP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF236 is perturbed and the expression of FILIP1L is measured. Does this perturbation cause a significant change in FILIP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79390
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYRM4 is associated with a significant change in NCAPH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYRM4 is associated with a significant change in NCAPH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83855
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, INTS5 is perturbed and MLLT11 expression is measured. Determine whether MLLT11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, INTS5 is perturbed and MLLT11 expression is measured. Determine whether MLLT11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61679
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EEF2 is perturbed and BTBD1 expression is quantified. Does this perturbation result in a significant change in BTBD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EEF2 is perturbed and BTBD1 expression is quantified. Does this perturbation result in a significant change in BTBD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36422
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SF3A2 is perturbed and the expression of ANKRD50 is measured. Does this perturbation cause a significant change in ANKRD50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SF3A2 is perturbed and the expression of ANKRD50 is measured. Does this perturbation cause a significant change in ANKRD50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8150
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX3X is perturbed and the expression of TM9SF4 is measured. Does this perturbation cause a significant change in TM9SF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX3X is perturbed and the expression of TM9SF4 is measured. Does this perturbation cause a significant change in TM9SF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41960
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAM136A, does the expression profile of EPAS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAM136A, does the expression profile of EPAS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6257
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOSC9 is perturbed and AEN expression is observed. Does this perturbation lead to a significant difference in AEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOSC9 is perturbed and AEN expression is observed. Does this perturbation lead to a significant difference in AEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120403
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of THAP1, does the expression profile of EHBP1L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of THAP1, does the expression profile of EHBP1L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20397
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TM7SF2 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TM7SF2 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23645
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS9, does the expression profile of DIAPH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS9, does the expression profile of DIAPH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49577
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GSPT1 and examine the expression of PDE1C. Does perturbing GSPT1 lead to a significant change in PDE1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GSPT1 and examine the expression of PDE1C. Does perturbing GSPT1 lead to a significant change in PDE1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102731
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNTB2 is perturbed and PIAS4 expression is observed. Does this perturbation lead to a significant difference in PIAS4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNTB2 is perturbed and PIAS4 expression is observed. Does this perturbation lead to a significant difference in PIAS4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120533
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF3 and examine the expression of MTRR. Does perturbing PRPF3 lead to a significant change in MTRR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF3 and examine the expression of MTRR. Does perturbing PRPF3 lead to a significant change in MTRR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23581
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCT6A, does the expression profile of SLC16A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCT6A, does the expression profile of SLC16A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119327
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and JRK expression is measured. Determine whether JRK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and JRK expression is measured. Determine whether JRK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50919
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS35, does the expression profile of PIP4K2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS35, does the expression profile of PIP4K2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23977
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN23 is perturbed and TRIM16 expression is measured. Determine whether TRIM16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN23 is perturbed and TRIM16 expression is measured. Determine whether TRIM16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105599
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HMGCS1 is perturbed and MYL12B expression is observed. Does this perturbation lead to a significant difference in MYL12B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HMGCS1 is perturbed and MYL12B expression is observed. Does this perturbation lead to a significant difference in MYL12B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33473
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TLN1 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TLN1 is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94443
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BUB3 and examine the expression of MRPL41. Does perturbing BUB3 lead to a significant change in MRPL41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BUB3 and examine the expression of MRPL41. Does perturbing BUB3 lead to a significant change in MRPL41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42141
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDX42 and then measure expression of NUP153. Does this perturbation cause a significant change in NUP153 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDX42 and then measure expression of NUP153. Does this perturbation cause a significant change in NUP153 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24674
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SDHAF2 and monitor NUDT16L1 expression. Decide whether this perturbation leads to a significant alteration in NUDT16L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SDHAF2 and monitor NUDT16L1 expression. Decide whether this perturbation leads to a significant alteration in NUDT16L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28248
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF1B is perturbed and NUDT14 expression is measured. Determine whether NUDT14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF1B is perturbed and NUDT14 expression is measured. Determine whether NUDT14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92139
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF1, does the expression profile of SYS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF1, does the expression profile of SYS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38667
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC1 is perturbed and JTB expression is measured. Determine whether JTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, THOC1 is perturbed and JTB expression is measured. Determine whether JTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100849
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFAF3 is perturbed and BCL2L2 expression is observed. Does this perturbation lead to a significant difference in BCL2L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NDUFAF3 is perturbed and BCL2L2 expression is observed. Does this perturbation lead to a significant difference in BCL2L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7993
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTBP4 and examine the expression of RALGAPA1. Does perturbing LTBP4 lead to a significant change in RALGAPA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTBP4 and examine the expression of RALGAPA1. Does perturbing LTBP4 lead to a significant change in RALGAPA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6041
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GRSF1 is associated with a significant change in AP1S1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GRSF1 is associated with a significant change in AP1S1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47285
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MSRB1, does the expression profile of CANT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MSRB1, does the expression profile of CANT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40207
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDCD6IP is perturbed and IFT20 expression is measured. Determine whether IFT20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDCD6IP is perturbed and IFT20 expression is measured. Determine whether IFT20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10079
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to METTL21A and then measure expression of EMG1. Does this perturbation cause a significant change in EMG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to METTL21A and then measure expression of EMG1. Does this perturbation cause a significant change in EMG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6924
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, USP9X is perturbed and IFT43 expression is quantified. Does this perturbation result in a significant change in IFT43 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, USP9X is perturbed and IFT43 expression is quantified. Does this perturbation result in a significant change in IFT43 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79782
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VMP1 is perturbed and GSK3A expression is quantified. Does this perturbation result in a significant change in GSK3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VMP1 is perturbed and GSK3A expression is quantified. Does this perturbation result in a significant change in GSK3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89002
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAT2A is perturbed and NUP43 expression is observed. Does this perturbation lead to a significant difference in NUP43 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAT2A is perturbed and NUP43 expression is observed. Does this perturbation lead to a significant difference in NUP43 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5633
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FGFR1OP is perturbed and ATF4 expression is quantified. Does this perturbation result in a significant change in ATF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FGFR1OP is perturbed and ATF4 expression is quantified. Does this perturbation result in a significant change in ATF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95472
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CTDP1 is perturbed and TBC1D23 expression is measured. Determine whether TBC1D23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CTDP1 is perturbed and TBC1D23 expression is measured. Determine whether TBC1D23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31209
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS3, does the expression profile of TRIM8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS3, does the expression profile of TRIM8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5737
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC9 and then measure expression of AEN. Does this perturbation cause a significant change in AEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC9 and then measure expression of AEN. Does this perturbation cause a significant change in AEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120404
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RTCB is perturbed and PRNP expression is quantified. Does this perturbation result in a significant change in PRNP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RTCB is perturbed and PRNP expression is quantified. Does this perturbation result in a significant change in PRNP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18442
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FAM136A and then measure expression of SEC31A. Does this perturbation cause a significant change in SEC31A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FAM136A and then measure expression of SEC31A. Does this perturbation cause a significant change in SEC31A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6274
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of BOLA2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of BOLA2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45247
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RNPS1 and examine the expression of ANKRA2. Does perturbing RNPS1 lead to a significant change in ANKRA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RNPS1 and examine the expression of ANKRA2. Does perturbing RNPS1 lead to a significant change in ANKRA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102571
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ALDOA is perturbed and the expression of ITM2C is measured. Determine whether ITM2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ALDOA is perturbed and the expression of ITM2C is measured. Determine whether ITM2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51766
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NPLOC4 is associated with a significant change in CCDC12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NPLOC4 is associated with a significant change in CCDC12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17895
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL22 is perturbed and the expression of PGGT1B is measured. Determine whether PGGT1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL22 is perturbed and the expression of PGGT1B is measured. Determine whether PGGT1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84116
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPA2 is perturbed and the expression of SGK3 is measured. Determine whether SGK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPA2 is perturbed and the expression of SGK3 is measured. Determine whether SGK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56676
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF2BP2 is perturbed and the expression of SNHG1 is measured. Does this perturbation cause a significant change in SNHG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF2BP2 is perturbed and the expression of SNHG1 is measured. Does this perturbation cause a significant change in SNHG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95570
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FUNDC2 is perturbed and the expression of RECK is measured. Determine whether RECK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FUNDC2 is perturbed and the expression of RECK is measured. Determine whether RECK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90036
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RTCB is perturbed and the expression of AGTPBP1 is measured. Does this perturbation cause a significant change in AGTPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RTCB is perturbed and the expression of AGTPBP1 is measured. Does this perturbation cause a significant change in AGTPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18480
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2K is perturbed and SARAF expression is quantified. Does this perturbation result in a significant change in SARAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2K is perturbed and SARAF expression is quantified. Does this perturbation result in a significant change in SARAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5842
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM4 is associated with a significant change in ZNF585A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM4 is associated with a significant change in ZNF585A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106975
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PITRM1 and examine the expression of AASDH. Does perturbing PITRM1 lead to a significant change in AASDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PITRM1 and examine the expression of AASDH. Does perturbing PITRM1 lead to a significant change in AASDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73231
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IRF2BP2 and monitor STMP1 expression. Decide whether this perturbation leads to a significant alteration in STMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IRF2BP2 and monitor STMP1 expression. Decide whether this perturbation leads to a significant alteration in STMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95608
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCAR1 and examine the expression of CNN2. Does perturbing BCAR1 lead to a significant change in CNN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCAR1 and examine the expression of CNN2. Does perturbing BCAR1 lead to a significant change in CNN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13841
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF6, does the expression profile of ANKMY2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF6, does the expression profile of ANKMY2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69867
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of NFU1 is measured. Determine whether NFU1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of NFU1 is measured. Determine whether NFU1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103246
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDT21 and examine the expression of CEBPG. Does perturbing NUDT21 lead to a significant change in CEBPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDT21 and examine the expression of CEBPG. Does perturbing NUDT21 lead to a significant change in CEBPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110001
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP14 is associated with a significant change in GPC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP14 is associated with a significant change in GPC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64985
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CWF19L2 is perturbed and POLR2I expression is measured. Determine whether POLR2I exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CWF19L2 is perturbed and POLR2I expression is measured. Determine whether POLR2I exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87389
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SYS1 and monitor TNFRSF10D expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SYS1 and monitor TNFRSF10D expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20008
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UXS1, does the expression profile of MGRN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UXS1, does the expression profile of MGRN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26527
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SDHA is perturbed and CDK5 expression is measured. Determine whether CDK5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SDHA is perturbed and CDK5 expression is measured. Determine whether CDK5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28819
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCAR1 is perturbed and LRRCC1 expression is measured. Determine whether LRRCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCAR1 is perturbed and LRRCC1 expression is measured. Determine whether LRRCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71899
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RCCD1 is perturbed and the expression of CHIC2 is measured. Determine whether CHIC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RCCD1 is perturbed and the expression of CHIC2 is measured. Determine whether CHIC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15276
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USPL1, does the expression profile of CREB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USPL1, does the expression profile of CREB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97267
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF84, does the expression profile of TPST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF84, does the expression profile of TPST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114437
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL18 and monitor FTSJ3 expression. Decide whether this perturbation leads to a significant alteration in FTSJ3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL18 and monitor FTSJ3 expression. Decide whether this perturbation leads to a significant alteration in FTSJ3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14248
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IST1 and examine the expression of DAZAP2. Does perturbing IST1 lead to a significant change in DAZAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IST1 and examine the expression of DAZAP2. Does perturbing IST1 lead to a significant change in DAZAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8471
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMG3 is associated with a significant change in ZNF496 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMG3 is associated with a significant change in ZNF496 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32205
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTK is perturbed and the expression of STX5 is measured. Determine whether STX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTK is perturbed and the expression of STX5 is measured. Determine whether STX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17566
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRAPPC8, does the expression profile of HSPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRAPPC8, does the expression profile of HSPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115687
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC16A and monitor TMEM208 expression. Decide whether this perturbation leads to a significant alteration in TMEM208 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC16A and monitor TMEM208 expression. Decide whether this perturbation leads to a significant alteration in TMEM208 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10658
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MFN2, does the expression profile of G0S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MFN2, does the expression profile of G0S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32747
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LEO1 is perturbed and MRPL41 expression is quantified. Does this perturbation result in a significant change in MRPL41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LEO1 is perturbed and MRPL41 expression is quantified. Does this perturbation result in a significant change in MRPL41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34372
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BET1 is associated with a significant change in UBE2K expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BET1 is associated with a significant change in UBE2K expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65205
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80C is perturbed and NRAS expression is quantified. Does this perturbation result in a significant change in NRAS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80C is perturbed and NRAS expression is quantified. Does this perturbation result in a significant change in NRAS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27162
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CYCS is perturbed and the expression of KRTAP2-3 is measured. Does this perturbation cause a significant change in KRTAP2-3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CYCS is perturbed and the expression of KRTAP2-3 is measured. Does this perturbation cause a significant change in KRTAP2-3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85710
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRNP70 is associated with a significant change in AC016831.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRNP70 is associated with a significant change in AC016831.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43775
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCS1L is perturbed and the expression of VAMP7 is measured. Does this perturbation cause a significant change in VAMP7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCS1L is perturbed and the expression of VAMP7 is measured. Does this perturbation cause a significant change in VAMP7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67490
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF2 is perturbed and GABARAPL1 expression is measured. Determine whether GABARAPL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF2 is perturbed and GABARAPL1 expression is measured. Determine whether GABARAPL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89899
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX56 is perturbed and the expression of FANCM is measured. Does this perturbation cause a significant change in FANCM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX56 is perturbed and the expression of FANCM is measured. Does this perturbation cause a significant change in FANCM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43270
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DROSHA, does the expression profile of SLC38A10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DROSHA, does the expression profile of SLC38A10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102467
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RAD51 and examine the expression of DAZAP2. Does perturbing RAD51 lead to a significant change in DAZAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RAD51 and examine the expression of DAZAP2. Does perturbing RAD51 lead to a significant change in DAZAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14141
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which WBP11 is perturbed and GIT1 expression is observed. Does this perturbation lead to a significant difference in GIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which WBP11 is perturbed and GIT1 expression is observed. Does this perturbation lead to a significant difference in GIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12603
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which METTL14 is perturbed and PTPRM expression is observed. Does this perturbation lead to a significant difference in PTPRM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which METTL14 is perturbed and PTPRM expression is observed. Does this perturbation lead to a significant difference in PTPRM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85063
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TCERG1 is perturbed and LYRM4 expression is observed. Does this perturbation lead to a significant difference in LYRM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TCERG1 is perturbed and LYRM4 expression is observed. Does this perturbation lead to a significant difference in LYRM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40173
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS28, does the expression profile of RTN4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS28, does the expression profile of RTN4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122787
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NPM1 is perturbed and TSPYL4 expression is quantified. Does this perturbation result in a significant change in TSPYL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NPM1 is perturbed and TSPYL4 expression is quantified. Does this perturbation result in a significant change in TSPYL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59652
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PAM16 and monitor LNPEP expression. Decide whether this perturbation leads to a significant alteration in LNPEP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PAM16 and monitor LNPEP expression. Decide whether this perturbation leads to a significant alteration in LNPEP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89558
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BMS1 and examine the expression of PCDH7. Does perturbing BMS1 lead to a significant change in PCDH7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BMS1 and examine the expression of PCDH7. Does perturbing BMS1 lead to a significant change in PCDH7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88341
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb VPS25 and monitor PPIH expression. Decide whether this perturbation leads to a significant alteration in PPIH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb VPS25 and monitor PPIH expression. Decide whether this perturbation leads to a significant alteration in PPIH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8658
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RFFL is perturbed and NENF expression is measured. Determine whether NENF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RFFL is perturbed and NENF expression is measured. Determine whether NENF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35519
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPA is perturbed and SAT1 expression is measured. Determine whether SAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPA is perturbed and SAT1 expression is measured. Determine whether SAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58529
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRMT10C is perturbed and SRFBP1 expression is measured. Determine whether SRFBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRMT10C is perturbed and SRFBP1 expression is measured. Determine whether SRFBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42369
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LENG8, does the expression profile of LYPLAL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LENG8, does the expression profile of LYPLAL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61647
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NUF2 and monitor RINT1 expression. Decide whether this perturbation leads to a significant alteration in RINT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NUF2 and monitor RINT1 expression. Decide whether this perturbation leads to a significant alteration in RINT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60038
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD3 is perturbed and GPC1 expression is quantified. Does this perturbation result in a significant change in GPC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD3 is perturbed and GPC1 expression is quantified. Does this perturbation result in a significant change in GPC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64872
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PFN1 is associated with a significant change in C6orf62 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PFN1 is associated with a significant change in C6orf62 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89785
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC27, does the expression profile of ELF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC27, does the expression profile of ELF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14767
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DPY19L4 is perturbed and STOM expression is observed. Does this perturbation lead to a significant difference in STOM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DPY19L4 is perturbed and STOM expression is observed. Does this perturbation lead to a significant difference in STOM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36613
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RRS1 is perturbed and ITPR1 expression is measured. Determine whether ITPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RRS1 is perturbed and ITPR1 expression is measured. Determine whether ITPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55709
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SF3B2 and then measure expression of ZNF24. Does this perturbation cause a significant change in ZNF24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SF3B2 and then measure expression of ZNF24. Does this perturbation cause a significant change in ZNF24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121774
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RAD51C is perturbed and MED13L expression is observed. Does this perturbation lead to a significant difference in MED13L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RAD51C is perturbed and MED13L expression is observed. Does this perturbation lead to a significant difference in MED13L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105483
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCP110 is perturbed and WASL expression is quantified. Does this perturbation result in a significant change in WASL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCP110 is perturbed and WASL expression is quantified. Does this perturbation result in a significant change in WASL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9202
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP10 is perturbed and the expression of PHLDA3 is measured. Determine whether PHLDA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, USP10 is perturbed and the expression of PHLDA3 is measured. Determine whether PHLDA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34636
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POT1 is associated with a significant change in DZIP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POT1 is associated with a significant change in DZIP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116685
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BRF1 is perturbed and GABPB1-AS1 expression is observed. Does this perturbation lead to a significant difference in GABPB1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BRF1 is perturbed and GABPB1-AS1 expression is observed. Does this perturbation lead to a significant difference in GABPB1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7893
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD11 is perturbed and BIN3 expression is quantified. Does this perturbation result in a significant change in BIN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD11 is perturbed and BIN3 expression is quantified. Does this perturbation result in a significant change in BIN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94882
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THAP11 and examine the expression of HMOX1. Does perturbing THAP11 lead to a significant change in HMOX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THAP11 and examine the expression of HMOX1. Does perturbing THAP11 lead to a significant change in HMOX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27071
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPV3L1, does the expression profile of MT-ND4L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPV3L1, does the expression profile of MT-ND4L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60117
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC23 is associated with a significant change in ELL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC23 is associated with a significant change in ELL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100745
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRNP1 and then measure expression of PARD3. Does this perturbation cause a significant change in PARD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRNP1 and then measure expression of PARD3. Does this perturbation cause a significant change in PARD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99314
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in SRPRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in SRPRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45215
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ALG1 is perturbed and the expression of ABHD2 is measured. Determine whether ABHD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ALG1 is perturbed and the expression of ABHD2 is measured. Determine whether ABHD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81646
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCOA4 and then measure expression of STRADA. Does this perturbation cause a significant change in STRADA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCOA4 and then measure expression of STRADA. Does this perturbation cause a significant change in STRADA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2414
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC137, does the expression profile of BHMT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC137, does the expression profile of BHMT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41267
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUT is perturbed and the expression of GLB1 is measured. Does this perturbation cause a significant change in GLB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUT is perturbed and the expression of GLB1 is measured. Does this perturbation cause a significant change in GLB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103960
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR77 is perturbed and RIDA expression is measured. Determine whether RIDA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR77 is perturbed and RIDA expression is measured. Determine whether RIDA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48429
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TWISTNB is associated with a significant change in TRIM38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TWISTNB is associated with a significant change in TRIM38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116795
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNPC3 is perturbed and MXD4 expression is measured. Determine whether MXD4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNPC3 is perturbed and MXD4 expression is measured. Determine whether MXD4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30499
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS5 is perturbed and the expression of KLC1 is measured. Does this perturbation cause a significant change in KLC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS5 is perturbed and the expression of KLC1 is measured. Does this perturbation cause a significant change in KLC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89070
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of TMEM128 is measured. Does this perturbation cause a significant change in TMEM128 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of TMEM128 is measured. Does this perturbation cause a significant change in TMEM128 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24960
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1143 is associated with a significant change in BFAR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1143 is associated with a significant change in BFAR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35025
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SETD1A and monitor MCRIP1 expression. Decide whether this perturbation leads to a significant alteration in MCRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SETD1A and monitor MCRIP1 expression. Decide whether this perturbation leads to a significant alteration in MCRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90848
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of PLXNA3 is measured. Does this perturbation cause a significant change in PLXNA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of PLXNA3 is measured. Does this perturbation cause a significant change in PLXNA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86400
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PKM and examine the expression of SP140. Does perturbing PKM lead to a significant change in SP140 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PKM and examine the expression of SP140. Does perturbing PKM lead to a significant change in SP140 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43831
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCDC115 is perturbed and CACNA2D1 expression is quantified. Does this perturbation result in a significant change in CACNA2D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCDC115 is perturbed and CACNA2D1 expression is quantified. Does this perturbation result in a significant change in CACNA2D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83172
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR61 is perturbed and the expression of SLC25A23 is measured. Does this perturbation cause a significant change in SLC25A23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR61 is perturbed and the expression of SLC25A23 is measured. Does this perturbation cause a significant change in SLC25A23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86360
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MCL1 is perturbed and AC093323.1 expression is quantified. Does this perturbation result in a significant change in AC093323.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MCL1 is perturbed and AC093323.1 expression is quantified. Does this perturbation result in a significant change in AC093323.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6722
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AP2M1 is perturbed and PPARD expression is measured. Determine whether PPARD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AP2M1 is perturbed and PPARD expression is measured. Determine whether PPARD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18319
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TKT is perturbed and ECM1 expression is measured. Determine whether ECM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TKT is perturbed and ECM1 expression is measured. Determine whether ECM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36859
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCKAP1 and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCKAP1 and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32904
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, H3F3A is perturbed and the expression of NDUFA12 is measured. Does this perturbation cause a significant change in NDUFA12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, H3F3A is perturbed and the expression of NDUFA12 is measured. Does this perturbation cause a significant change in NDUFA12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3180
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C1orf109, does the expression profile of ZCCHC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C1orf109, does the expression profile of ZCCHC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35337
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNHIT3 is associated with a significant change in TRPT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNHIT3 is associated with a significant change in TRPT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48215
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS8 is perturbed and the expression of AC100810.1 is measured. Does this perturbation cause a significant change in AC100810.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS8 is perturbed and the expression of AC100810.1 is measured. Does this perturbation cause a significant change in AC100810.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92880
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SUDS3 is associated with a significant change in DLEU2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SUDS3 is associated with a significant change in DLEU2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57445
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23B and monitor FAP expression. Decide whether this perturbation leads to a significant alteration in FAP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23B and monitor FAP expression. Decide whether this perturbation leads to a significant alteration in FAP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16538
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCP110 is associated with a significant change in SELENOM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCP110 is associated with a significant change in SELENOM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9225
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL28 is perturbed and DNAJC4 expression is measured. Determine whether DNAJC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL28 is perturbed and DNAJC4 expression is measured. Determine whether DNAJC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39809
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LAMB1 and monitor IFRD1 expression. Decide whether this perturbation leads to a significant alteration in IFRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LAMB1 and monitor IFRD1 expression. Decide whether this perturbation leads to a significant alteration in IFRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55598
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS23, does the expression profile of CPOX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS23, does the expression profile of CPOX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23477
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOSC3, does the expression profile of RNF25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOSC3, does the expression profile of RNF25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98367
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNTB2 and then measure expression of DSTYK. Does this perturbation cause a significant change in DSTYK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNTB2 and then measure expression of DSTYK. Does this perturbation cause a significant change in DSTYK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120574
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDC42 and monitor SREK1IP1 expression. Decide whether this perturbation leads to a significant alteration in SREK1IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDC42 and monitor SREK1IP1 expression. Decide whether this perturbation leads to a significant alteration in SREK1IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86658
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POGZ is perturbed and NHLRC3 expression is measured. Determine whether NHLRC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POGZ is perturbed and NHLRC3 expression is measured. Determine whether NHLRC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62309
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PGAM1 is perturbed and ENTPD6 expression is quantified. Does this perturbation result in a significant change in ENTPD6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PGAM1 is perturbed and ENTPD6 expression is quantified. Does this perturbation result in a significant change in ENTPD6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106602
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUBP1 is associated with a significant change in BBS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUBP1 is associated with a significant change in BBS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99705
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLPB is associated with a significant change in RAB30-DT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLPB is associated with a significant change in RAB30-DT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42235
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103098
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PXN, does the expression profile of SUGCT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PXN, does the expression profile of SUGCT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48647
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA3 and then measure expression of ICE2. Does this perturbation cause a significant change in ICE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA3 and then measure expression of ICE2. Does this perturbation cause a significant change in ICE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36454
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP43 and examine the expression of BDNF. Does perturbing NUP43 lead to a significant change in BDNF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP43 and examine the expression of BDNF. Does perturbing NUP43 lead to a significant change in BDNF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79561
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of RHOQ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of RHOQ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109017
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TOPBP1 is perturbed and SYF2 expression is quantified. Does this perturbation result in a significant change in SYF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TOPBP1 is perturbed and SYF2 expression is quantified. Does this perturbation result in a significant change in SYF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78542
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GGPS1 is associated with a significant change in GATAD2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GGPS1 is associated with a significant change in GATAD2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86935
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of THAP11, does the expression profile of UBXN8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of THAP11, does the expression profile of UBXN8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27047
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC5 is perturbed and WARS expression is observed. Does this perturbation lead to a significant difference in WARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC5 is perturbed and WARS expression is observed. Does this perturbation lead to a significant difference in WARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41993
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUD13 is associated with a significant change in DUSP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUD13 is associated with a significant change in DUSP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110075
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PFDN1 is perturbed and the expression of ERLEC1 is measured. Determine whether ERLEC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PFDN1 is perturbed and the expression of ERLEC1 is measured. Determine whether ERLEC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28136
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METTL17 is perturbed and LINC02454 expression is quantified. Does this perturbation result in a significant change in LINC02454 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METTL17 is perturbed and LINC02454 expression is quantified. Does this perturbation result in a significant change in LINC02454 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47962
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL12 is perturbed and NSRP1 expression is measured. Determine whether NSRP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL12 is perturbed and NSRP1 expression is measured. Determine whether NSRP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25949
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMA16 is associated with a significant change in DNAAF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMA16 is associated with a significant change in DNAAF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100115
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RANBP2 is perturbed and the expression of GGA1 is measured. Does this perturbation cause a significant change in GGA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RANBP2 is perturbed and the expression of GGA1 is measured. Does this perturbation cause a significant change in GGA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86450
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of ATXN3 is measured. Does this perturbation cause a significant change in ATXN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of ATXN3 is measured. Does this perturbation cause a significant change in ATXN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20730
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS31 is perturbed and DNAJC19 expression is observed. Does this perturbation lead to a significant difference in DNAJC19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS31 is perturbed and DNAJC19 expression is observed. Does this perturbation lead to a significant difference in DNAJC19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD4 is perturbed and ANGPT1 expression is quantified. Does this perturbation result in a significant change in ANGPT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD4 is perturbed and ANGPT1 expression is quantified. Does this perturbation result in a significant change in ANGPT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61272
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARMC6 is perturbed and POMGNT1 expression is measured. Determine whether POMGNT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARMC6 is perturbed and POMGNT1 expression is measured. Determine whether POMGNT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58369
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DSN1 and examine the expression of EXOC1. Does perturbing DSN1 lead to a significant change in EXOC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DSN1 and examine the expression of EXOC1. Does perturbing DSN1 lead to a significant change in EXOC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96651
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SUPV3L1 is perturbed and MT-ND4L expression is measured. Determine whether MT-ND4L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SUPV3L1 is perturbed and MT-ND4L expression is measured. Determine whether MT-ND4L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60119
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2F1 is perturbed and VCPIP1 expression is measured. Determine whether VCPIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2F1 is perturbed and VCPIP1 expression is measured. Determine whether VCPIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24039
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COG3 and monitor PMEPA1 expression. Decide whether this perturbation leads to a significant alteration in PMEPA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COG3 and monitor PMEPA1 expression. Decide whether this perturbation leads to a significant alteration in PMEPA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15218
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PHB2 is perturbed and UNC93B1 expression is quantified. Does this perturbation result in a significant change in UNC93B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PHB2 is perturbed and UNC93B1 expression is quantified. Does this perturbation result in a significant change in UNC93B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63942
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MED6 is perturbed and DHRSX expression is quantified. Does this perturbation result in a significant change in DHRSX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MED6 is perturbed and DHRSX expression is quantified. Does this perturbation result in a significant change in DHRSX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108742
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRKCA and examine the expression of SLC30A7. Does perturbing PRKCA lead to a significant change in SLC30A7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRKCA and examine the expression of SLC30A7. Does perturbing PRKCA lead to a significant change in SLC30A7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54121
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SETD2 is perturbed and SERINC5 expression is observed. Does this perturbation lead to a significant difference in SERINC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SETD2 is perturbed and SERINC5 expression is observed. Does this perturbation lead to a significant difference in SERINC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82113
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPH is associated with a significant change in TRIM52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPH is associated with a significant change in TRIM52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60515
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIN is associated with a significant change in YIPF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIN is associated with a significant change in YIPF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90425
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLU7 is perturbed and the expression of ARFIP2 is measured. Does this perturbation cause a significant change in ARFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLU7 is perturbed and the expression of ARFIP2 is measured. Does this perturbation cause a significant change in ARFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44850
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which E2F6 is perturbed and PREB expression is observed. Does this perturbation lead to a significant difference in PREB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which E2F6 is perturbed and PREB expression is observed. Does this perturbation lead to a significant difference in PREB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40903
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOL8, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOL8, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34707
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MFAP1 is perturbed and the expression of SPATA7 is measured. Determine whether SPATA7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MFAP1 is perturbed and the expression of SPATA7 is measured. Determine whether SPATA7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9546
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED7 is associated with a significant change in ATP6V1D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED7 is associated with a significant change in ATP6V1D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106515
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF4A3 is perturbed and EMC2 expression is observed. Does this perturbation lead to a significant difference in EMC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF4A3 is perturbed and EMC2 expression is observed. Does this perturbation lead to a significant difference in EMC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68743
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAXX is associated with a significant change in CRIM1-DT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAXX is associated with a significant change in CRIM1-DT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52655
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRPF18, does the expression profile of BRAP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRPF18, does the expression profile of BRAP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45527
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NUDCD3 and monitor MPDZ expression. Decide whether this perturbation leads to a significant alteration in MPDZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NUDCD3 and monitor MPDZ expression. Decide whether this perturbation leads to a significant alteration in MPDZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9838
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP205 and examine the expression of ROGDI. Does perturbing NUP205 lead to a significant change in ROGDI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP205 and examine the expression of ROGDI. Does perturbing NUP205 lead to a significant change in ROGDI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103651
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCAF6 is associated with a significant change in COA7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCAF6 is associated with a significant change in COA7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6555
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC37 is perturbed and the expression of GLUD1 is measured. Does this perturbation cause a significant change in GLUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDC37 is perturbed and the expression of GLUD1 is measured. Does this perturbation cause a significant change in GLUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122230
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAPC4 and monitor G0S2 expression. Decide whether this perturbation leads to a significant alteration in G0S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAPC4 and monitor G0S2 expression. Decide whether this perturbation leads to a significant alteration in G0S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48168
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SYNE1 expression is observed. Does this perturbation lead to a significant difference in SYNE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SYNE1 expression is observed. Does this perturbation lead to a significant difference in SYNE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116003
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS51 is perturbed and the expression of SELENOM is measured. Determine whether SELENOM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS51 is perturbed and the expression of SELENOM is measured. Determine whether SELENOM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87016
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIN is perturbed and the expression of PI4K2A is measured. Determine whether PI4K2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIN is perturbed and the expression of PI4K2A is measured. Determine whether PI4K2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90466
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF407 and examine the expression of HAUS2. Does perturbing ZNF407 lead to a significant change in HAUS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF407 and examine the expression of HAUS2. Does perturbing ZNF407 lead to a significant change in HAUS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108601
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CLCC1 and monitor HPS3 expression. Decide whether this perturbation leads to a significant alteration in HPS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CLCC1 and monitor HPS3 expression. Decide whether this perturbation leads to a significant alteration in HPS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18938
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM10 is perturbed and BDH2 expression is measured. Determine whether BDH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM10 is perturbed and BDH2 expression is measured. Determine whether BDH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16369
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2H3 is associated with a significant change in MPV17 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF2H3 is associated with a significant change in MPV17 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58285
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLMN is perturbed and AAR2 expression is quantified. Does this perturbation result in a significant change in AAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLMN is perturbed and AAR2 expression is quantified. Does this perturbation result in a significant change in AAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123462
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZFC3H1 is associated with a significant change in GPALPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZFC3H1 is associated with a significant change in GPALPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32395
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KEAP1 and examine the expression of MRNIP. Does perturbing KEAP1 lead to a significant change in MRNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KEAP1 and examine the expression of MRNIP. Does perturbing KEAP1 lead to a significant change in MRNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18071
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to THOC7 and then measure expression of DDX27. Does this perturbation cause a significant change in DDX27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to THOC7 and then measure expression of DDX27. Does this perturbation cause a significant change in DDX27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27444
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UMPS is perturbed and SEC23B expression is observed. Does this perturbation lead to a significant difference in SEC23B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UMPS is perturbed and SEC23B expression is observed. Does this perturbation lead to a significant difference in SEC23B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94843
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LARS is perturbed and the expression of RB1CC1 is measured. Does this perturbation cause a significant change in RB1CC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LARS is perturbed and the expression of RB1CC1 is measured. Does this perturbation cause a significant change in RB1CC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86870
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRIP1 is associated with a significant change in RHOA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRIP1 is associated with a significant change in RHOA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51975
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of MKNK1 is measured. Determine whether MKNK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of MKNK1 is measured. Determine whether MKNK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14566
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GAPDH is perturbed and the expression of DDX27 is measured. Does this perturbation cause a significant change in DDX27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GAPDH is perturbed and the expression of DDX27 is measured. Does this perturbation cause a significant change in DDX27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54490
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of F8A1. Does this perturbation cause a significant change in F8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of F8A1. Does this perturbation cause a significant change in F8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94994
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AKIRIN2 is perturbed and RRAS expression is measured. Determine whether RRAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AKIRIN2 is perturbed and RRAS expression is measured. Determine whether RRAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74219
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD14 and examine the expression of SETD5. Does perturbing PSMD14 lead to a significant change in SETD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD14 and examine the expression of SETD5. Does perturbing PSMD14 lead to a significant change in SETD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64011
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAD2L1 is perturbed and the expression of GBP1 is measured. Does this perturbation cause a significant change in GBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAD2L1 is perturbed and the expression of GBP1 is measured. Does this perturbation cause a significant change in GBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33190
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KRT10 is perturbed and NARS2 expression is observed. Does this perturbation lead to a significant difference in NARS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KRT10 is perturbed and NARS2 expression is observed. Does this perturbation lead to a significant difference in NARS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30413
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FIP1L1 is perturbed and the expression of MRPL33 is measured. Does this perturbation cause a significant change in MRPL33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FIP1L1 is perturbed and the expression of MRPL33 is measured. Does this perturbation cause a significant change in MRPL33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121540
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPS is perturbed and PSMD10 expression is quantified. Does this perturbation result in a significant change in PSMD10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPS is perturbed and PSMD10 expression is quantified. Does this perturbation result in a significant change in PSMD10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11942
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR33 is perturbed and the expression of TP53TG1 is measured. Determine whether TP53TG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR33 is perturbed and the expression of TP53TG1 is measured. Determine whether TP53TG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31706
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FNTA and examine the expression of POLD4. Does perturbing FNTA lead to a significant change in POLD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FNTA and examine the expression of POLD4. Does perturbing FNTA lead to a significant change in POLD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111121
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and MOB2 expression is observed. Does this perturbation lead to a significant difference in MOB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and MOB2 expression is observed. Does this perturbation lead to a significant difference in MOB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50933
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET1 is associated with a significant change in ADAMTS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET1 is associated with a significant change in ADAMTS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21575
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBX1 and then measure expression of ZBTB44. Does this perturbation cause a significant change in ZBTB44 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBX1 and then measure expression of ZBTB44. Does this perturbation cause a significant change in ZBTB44 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90784
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BANP is perturbed and the expression of CNN3 is measured. Determine whether CNN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BANP is perturbed and the expression of CNN3 is measured. Determine whether CNN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121056
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of THRAP3 is associated with a significant change in MYEF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of THRAP3 is associated with a significant change in MYEF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97385
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS11 and examine the expression of CENPA. Does perturbing MRPS11 lead to a significant change in CENPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS11 and examine the expression of CENPA. Does perturbing MRPS11 lead to a significant change in CENPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8741
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL28 is perturbed and the expression of TVP23B is measured. Does this perturbation cause a significant change in TVP23B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL28 is perturbed and the expression of TVP23B is measured. Does this perturbation cause a significant change in TVP23B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39830
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TEFM is associated with a significant change in MAGI2-AS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TEFM is associated with a significant change in MAGI2-AS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34025
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL27A is perturbed and the expression of TOMM7 is measured. Determine whether TOMM7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL27A is perturbed and the expression of TOMM7 is measured. Determine whether TOMM7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108446
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PEX19, does the expression profile of SRA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PEX19, does the expression profile of SRA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69397
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSBP and then measure expression of ITGAV. Does this perturbation cause a significant change in ITGAV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSBP and then measure expression of ITGAV. Does this perturbation cause a significant change in ITGAV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96304
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBLL1 is perturbed and FAM155A expression is measured. Determine whether FAM155A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBLL1 is perturbed and FAM155A expression is measured. Determine whether FAM155A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95549
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1F is perturbed and PFKFB4 expression is measured. Determine whether PFKFB4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1F is perturbed and PFKFB4 expression is measured. Determine whether PFKFB4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105209
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of DEF8 is measured. Determine whether DEF8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of DEF8 is measured. Determine whether DEF8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121316
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PET117 is perturbed and ZFHX4 expression is quantified. Does this perturbation result in a significant change in ZFHX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PET117 is perturbed and ZFHX4 expression is quantified. Does this perturbation result in a significant change in ZFHX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100292
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS7 is perturbed and AKT2 expression is observed. Does this perturbation lead to a significant difference in AKT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS7 is perturbed and AKT2 expression is observed. Does this perturbation lead to a significant difference in AKT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82593
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP62 is perturbed and the expression of AC005670.3 is measured. Determine whether AC005670.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP62 is perturbed and the expression of AC005670.3 is measured. Determine whether AC005670.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117806
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KATNB1 is perturbed and PLAT expression is measured. Determine whether PLAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KATNB1 is perturbed and PLAT expression is measured. Determine whether PLAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113949
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UNC45A and examine the expression of CASP2. Does perturbing UNC45A lead to a significant change in CASP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UNC45A and examine the expression of CASP2. Does perturbing UNC45A lead to a significant change in CASP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9191
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD39 is associated with a significant change in ZNF576 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD39 is associated with a significant change in ZNF576 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116235
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HMGCR is perturbed and YME1L1 expression is quantified. Does this perturbation result in a significant change in YME1L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HMGCR is perturbed and YME1L1 expression is quantified. Does this perturbation result in a significant change in YME1L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90952
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF5 is associated with a significant change in TARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF5 is associated with a significant change in TARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119665
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL13 is perturbed and ENTPD7 expression is observed. Does this perturbation lead to a significant difference in ENTPD7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL13 is perturbed and ENTPD7 expression is observed. Does this perturbation lead to a significant difference in ENTPD7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80713
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BMS1 is perturbed and PON2 expression is measured. Determine whether PON2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BMS1 is perturbed and PON2 expression is measured. Determine whether PON2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88339
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ILF3 is perturbed and TUSC2 expression is observed. Does this perturbation lead to a significant difference in TUSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ILF3 is perturbed and TUSC2 expression is observed. Does this perturbation lead to a significant difference in TUSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72833
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PHF5A is perturbed and CCDC50 expression is measured. Determine whether CCDC50 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PHF5A is perturbed and CCDC50 expression is measured. Determine whether CCDC50 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99049
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ERH is perturbed and SUN1 expression is observed. Does this perturbation lead to a significant difference in SUN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ERH is perturbed and SUN1 expression is observed. Does this perturbation lead to a significant difference in SUN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109463
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD6, does the expression profile of BRD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD6, does the expression profile of BRD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78717
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNOT1 is perturbed and RSPH3 expression is quantified. Does this perturbation result in a significant change in RSPH3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNOT1 is perturbed and RSPH3 expression is quantified. Does this perturbation result in a significant change in RSPH3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50212
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QRSL1 is perturbed and AGO3 expression is quantified. Does this perturbation result in a significant change in AGO3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QRSL1 is perturbed and AGO3 expression is quantified. Does this perturbation result in a significant change in AGO3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27762
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HAUS3 is perturbed and AGBL5 expression is observed. Does this perturbation lead to a significant difference in AGBL5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HAUS3 is perturbed and AGBL5 expression is observed. Does this perturbation lead to a significant difference in AGBL5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":713
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SHC1 is perturbed and the expression of MAP4K5 is measured. Determine whether MAP4K5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SHC1 is perturbed and the expression of MAP4K5 is measured. Determine whether MAP4K5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23146
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UPF2 and monitor TENT2 expression. Decide whether this perturbation leads to a significant alteration in TENT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UPF2 and monitor TENT2 expression. Decide whether this perturbation leads to a significant alteration in TENT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19198
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCBP2 is perturbed and WDR37 expression is measured. Determine whether WDR37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCBP2 is perturbed and WDR37 expression is measured. Determine whether WDR37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90579
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM242 is associated with a significant change in CAMK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM242 is associated with a significant change in CAMK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5525
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SKA1 is perturbed and the expression of IFNAR2 is measured. Determine whether IFNAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SKA1 is perturbed and the expression of IFNAR2 is measured. Determine whether IFNAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66266
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C7orf50 is associated with a significant change in H2AFY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C7orf50 is associated with a significant change in H2AFY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112555
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM8 and then measure expression of IMMT. Does this perturbation cause a significant change in IMMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM8 and then measure expression of IMMT. Does this perturbation cause a significant change in IMMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118964
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMA16 and monitor BHMT2 expression. Decide whether this perturbation leads to a significant alteration in BHMT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMA16 and monitor BHMT2 expression. Decide whether this perturbation leads to a significant alteration in BHMT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100108
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZCCHC9 and examine the expression of TRIM25. Does perturbing ZCCHC9 lead to a significant change in TRIM25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZCCHC9 and examine the expression of TRIM25. Does perturbing ZCCHC9 lead to a significant change in TRIM25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78701
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SUGT1 is perturbed and ZYG11B expression is observed. Does this perturbation lead to a significant difference in ZYG11B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SUGT1 is perturbed and ZYG11B expression is observed. Does this perturbation lead to a significant difference in ZYG11B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113623
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPRC1 is associated with a significant change in PFDN6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPRC1 is associated with a significant change in PFDN6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99615
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PAF1 is perturbed and ENC1 expression is measured. Determine whether ENC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PAF1 is perturbed and ENC1 expression is measured. Determine whether ENC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15539
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAX and examine the expression of NDST2. Does perturbing MAX lead to a significant change in NDST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAX and examine the expression of NDST2. Does perturbing MAX lead to a significant change in NDST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95901
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCAF6 is perturbed and RPL10A expression is quantified. Does this perturbation result in a significant change in RPL10A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCAF6 is perturbed and RPL10A expression is quantified. Does this perturbation result in a significant change in RPL10A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6582
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HMGA1 is perturbed and WDR6 expression is observed. Does this perturbation lead to a significant difference in WDR6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HMGA1 is perturbed and WDR6 expression is observed. Does this perturbation lead to a significant difference in WDR6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8003
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3A, does the expression profile of SNHG32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3A, does the expression profile of SNHG32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51037
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DROSHA is perturbed and MIRLET7BHG expression is observed. Does this perturbation lead to a significant difference in MIRLET7BHG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DROSHA is perturbed and MIRLET7BHG expression is observed. Does this perturbation lead to a significant difference in MIRLET7BHG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102433
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PHF10 and then measure expression of LHFPL2. Does this perturbation cause a significant change in LHFPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PHF10 and then measure expression of LHFPL2. Does this perturbation cause a significant change in LHFPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21684
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POP5 is perturbed and LINC02742 expression is observed. Does this perturbation lead to a significant difference in LINC02742 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POP5 is perturbed and LINC02742 expression is observed. Does this perturbation lead to a significant difference in LINC02742 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73343
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELOB is perturbed and the expression of WASHC3 is measured. Determine whether WASHC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELOB is perturbed and the expression of WASHC3 is measured. Determine whether WASHC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11256
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPC is associated with a significant change in MRPS33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPC is associated with a significant change in MRPS33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78875
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DPH6 and monitor ZNF217 expression. Decide whether this perturbation leads to a significant alteration in ZNF217 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DPH6 and monitor ZNF217 expression. Decide whether this perturbation leads to a significant alteration in ZNF217 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54718
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UQCRH is perturbed and the expression of RPL39L is measured. Determine whether RPL39L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UQCRH is perturbed and the expression of RPL39L is measured. Determine whether RPL39L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94536
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBBP5 is associated with a significant change in POLL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBBP5 is associated with a significant change in POLL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74035
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRC1, does the expression profile of RFX7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRC1, does the expression profile of RFX7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1677
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PAK1IP1 is perturbed and the expression of DUSP3 is measured. Does this perturbation cause a significant change in DUSP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PAK1IP1 is perturbed and the expression of DUSP3 is measured. Does this perturbation cause a significant change in DUSP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71340
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MSRB1, does the expression profile of TMED5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MSRB1, does the expression profile of TMED5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40237
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDK12, does the expression profile of GID4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDK12, does the expression profile of GID4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103067
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPL10A and monitor GET3 expression. Decide whether this perturbation leads to a significant alteration in GET3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPL10A and monitor GET3 expression. Decide whether this perturbation leads to a significant alteration in GET3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87428
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJA3 is associated with a significant change in EPAS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJA3 is associated with a significant change in EPAS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29145
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRC1 and then measure expression of RFX7. Does this perturbation cause a significant change in RFX7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRC1 and then measure expression of RFX7. Does this perturbation cause a significant change in RFX7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1674
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS2 is perturbed and RBM22 expression is quantified. Does this perturbation result in a significant change in RBM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS2 is perturbed and RBM22 expression is quantified. Does this perturbation result in a significant change in RBM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63452
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS2 and then measure expression of THAP6. Does this perturbation cause a significant change in THAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS2 and then measure expression of THAP6. Does this perturbation cause a significant change in THAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80154
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WTAP, does the expression profile of TRIM8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WTAP, does the expression profile of TRIM8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41757
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CAP1 and monitor ZNF787 expression. Decide whether this perturbation leads to a significant alteration in ZNF787 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CAP1 and monitor ZNF787 expression. Decide whether this perturbation leads to a significant alteration in ZNF787 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73438
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2I is associated with a significant change in ANKS6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2I is associated with a significant change in ANKS6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16935
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, N6AMT1 is perturbed and CEP57L1 expression is quantified. Does this perturbation result in a significant change in CEP57L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, N6AMT1 is perturbed and CEP57L1 expression is quantified. Does this perturbation result in a significant change in CEP57L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2452
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALDOA, does the expression profile of ORC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALDOA, does the expression profile of ORC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51797
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC1 is perturbed and CCNK expression is observed. Does this perturbation lead to a significant difference in CCNK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC1 is perturbed and CCNK expression is observed. Does this perturbation lead to a significant difference in CCNK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119983
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHPS is perturbed and NTAN1 expression is measured. Determine whether NTAN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHPS is perturbed and NTAN1 expression is measured. Determine whether NTAN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10509
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YPEL5 is associated with a significant change in FAM13A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YPEL5 is associated with a significant change in FAM13A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44365
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KRT10 and monitor SLC25A13 expression. Decide whether this perturbation leads to a significant alteration in SLC25A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KRT10 and monitor SLC25A13 expression. Decide whether this perturbation leads to a significant alteration in SLC25A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30378
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which WDHD1 is perturbed and DAB2 expression is observed. Does this perturbation lead to a significant difference in DAB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which WDHD1 is perturbed and DAB2 expression is observed. Does this perturbation lead to a significant difference in DAB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96593
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDPK1, does the expression profile of NDUFB8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDPK1, does the expression profile of NDUFB8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81167
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TUBA1B is perturbed and SLC44A2 expression is observed. Does this perturbation lead to a significant difference in SLC44A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TUBA1B is perturbed and SLC44A2 expression is observed. Does this perturbation lead to a significant difference in SLC44A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82313
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3H4 is perturbed and LAMTOR5 expression is quantified. Does this perturbation result in a significant change in LAMTOR5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3H4 is perturbed and LAMTOR5 expression is quantified. Does this perturbation result in a significant change in LAMTOR5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22562
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBMX2 is perturbed and METTL16 expression is quantified. Does this perturbation result in a significant change in METTL16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBMX2 is perturbed and METTL16 expression is quantified. Does this perturbation result in a significant change in METTL16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51812
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PARN is perturbed and the expression of SULF1 is measured. Does this perturbation cause a significant change in SULF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PARN is perturbed and the expression of SULF1 is measured. Does this perturbation cause a significant change in SULF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37260
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFS5 is perturbed and ARL6IP6 expression is quantified. Does this perturbation result in a significant change in ARL6IP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFS5 is perturbed and ARL6IP6 expression is quantified. Does this perturbation result in a significant change in ARL6IP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2192
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CD2BP2 is perturbed and the expression of SKIV2L is measured. Does this perturbation cause a significant change in SKIV2L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CD2BP2 is perturbed and the expression of SKIV2L is measured. Does this perturbation cause a significant change in SKIV2L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99820
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC11 is associated with a significant change in ECHDC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC11 is associated with a significant change in ECHDC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31985
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PREB is perturbed and the expression of PLA2G4A is measured. Determine whether PLA2G4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PREB is perturbed and the expression of PLA2G4A is measured. Determine whether PLA2G4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98446
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AP2S1 and then measure expression of TOE1. Does this perturbation cause a significant change in TOE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AP2S1 and then measure expression of TOE1. Does this perturbation cause a significant change in TOE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118724
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TOPBP1 is perturbed and GSK3B expression is observed. Does this perturbation lead to a significant difference in GSK3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TOPBP1 is perturbed and GSK3B expression is observed. Does this perturbation lead to a significant difference in GSK3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78583
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELP6 is perturbed and the expression of DTD2 is measured. Determine whether DTD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELP6 is perturbed and the expression of DTD2 is measured. Determine whether DTD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46636
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNL3 is perturbed and MLH3 expression is observed. Does this perturbation lead to a significant difference in MLH3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNL3 is perturbed and MLH3 expression is observed. Does this perturbation lead to a significant difference in MLH3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55523
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNOT2, does the expression profile of MTCH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNOT2, does the expression profile of MTCH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16797
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP192 and then measure expression of INTS10. Does this perturbation cause a significant change in INTS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP192 and then measure expression of INTS10. Does this perturbation cause a significant change in INTS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29214
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PWP1 is perturbed and the expression of PSEN2 is measured. Does this perturbation cause a significant change in PSEN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PWP1 is perturbed and the expression of PSEN2 is measured. Does this perturbation cause a significant change in PSEN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107370
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SMC6 and examine the expression of MRAS. Does perturbing SMC6 lead to a significant change in MRAS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SMC6 and examine the expression of MRAS. Does perturbing SMC6 lead to a significant change in MRAS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95661
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3A is perturbed and SNHG32 expression is quantified. Does this perturbation result in a significant change in SNHG32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3A is perturbed and SNHG32 expression is quantified. Does this perturbation result in a significant change in SNHG32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51032
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BYSL is perturbed and the expression of ZNHIT1 is measured. Determine whether ZNHIT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BYSL is perturbed and the expression of ZNHIT1 is measured. Determine whether ZNHIT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110656
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF6 is associated with a significant change in ZRANB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF6 is associated with a significant change in ZRANB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30295
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LAMTOR3 is perturbed and RRAGB expression is observed. Does this perturbation lead to a significant difference in RRAGB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LAMTOR3 is perturbed and RRAGB expression is observed. Does this perturbation lead to a significant difference in RRAGB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79923
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRIX1 is associated with a significant change in FAP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRIX1 is associated with a significant change in FAP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86585
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL55 is perturbed and MFN1 expression is measured. Determine whether MFN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL55 is perturbed and MFN1 expression is measured. Determine whether MFN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79519
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC84, does the expression profile of C2orf76 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC84, does the expression profile of C2orf76 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23027
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYMPK is perturbed and IFT20 expression is observed. Does this perturbation lead to a significant difference in IFT20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYMPK is perturbed and IFT20 expression is observed. Does this perturbation lead to a significant difference in IFT20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33133
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COG1 and monitor LBH expression. Decide whether this perturbation leads to a significant alteration in LBH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COG1 and monitor LBH expression. Decide whether this perturbation leads to a significant alteration in LBH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67568
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, METAP1 is perturbed and the expression of SGTB is measured. Determine whether SGTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, METAP1 is perturbed and the expression of SGTB is measured. Determine whether SGTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107976
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSAT1 is associated with a significant change in CHMP1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSAT1 is associated with a significant change in CHMP1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69175
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAP30BP is associated with a significant change in KCNK6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAP30BP is associated with a significant change in KCNK6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6215
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDK6, does the expression profile of RHBDD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDK6, does the expression profile of RHBDD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37707
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS7 is perturbed and RIOK3 expression is quantified. Does this perturbation result in a significant change in RIOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS7 is perturbed and RIOK3 expression is quantified. Does this perturbation result in a significant change in RIOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114602
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRRC2A and monitor NFKBIL1 expression. Decide whether this perturbation leads to a significant alteration in NFKBIL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRRC2A and monitor NFKBIL1 expression. Decide whether this perturbation leads to a significant alteration in NFKBIL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9788
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PI4KA is perturbed and TPRA1 expression is quantified. Does this perturbation result in a significant change in TPRA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PI4KA is perturbed and TPRA1 expression is quantified. Does this perturbation result in a significant change in TPRA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49032
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TUBGCP3 is perturbed and SETDB1 expression is observed. Does this perturbation lead to a significant difference in SETDB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TUBGCP3 is perturbed and SETDB1 expression is observed. Does this perturbation lead to a significant difference in SETDB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89843
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of C5orf46. Does this perturbation cause a significant change in C5orf46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of C5orf46. Does this perturbation cause a significant change in C5orf46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94984
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOMM22 and then measure expression of GNS. Does this perturbation cause a significant change in GNS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOMM22 and then measure expression of GNS. Does this perturbation cause a significant change in GNS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95204
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP10 and then measure expression of COPZ2. Does this perturbation cause a significant change in COPZ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP10 and then measure expression of COPZ2. Does this perturbation cause a significant change in COPZ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120174
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HECTD1 is perturbed and FNIP2 expression is quantified. Does this perturbation result in a significant change in FNIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HECTD1 is perturbed and FNIP2 expression is quantified. Does this perturbation result in a significant change in FNIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10232
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AKIRIN2 is perturbed and TTN-AS1 expression is measured. Determine whether TTN-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AKIRIN2 is perturbed and TTN-AS1 expression is measured. Determine whether TTN-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74249
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC3 and then measure expression of GPATCH2L. Does this perturbation cause a significant change in GPATCH2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC3 and then measure expression of GPATCH2L. Does this perturbation cause a significant change in GPATCH2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16184
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC8 is perturbed and PYCR1 expression is measured. Determine whether PYCR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRAPPC8 is perturbed and PYCR1 expression is measured. Determine whether PYCR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115709
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of PDLIM4. Does perturbing CCT5 lead to a significant change in PDLIM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of PDLIM4. Does perturbing CCT5 lead to a significant change in PDLIM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123601
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RSL24D1 is perturbed and the expression of PAPPA is measured. Does this perturbation cause a significant change in PAPPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RSL24D1 is perturbed and the expression of PAPPA is measured. Does this perturbation cause a significant change in PAPPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53690
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NF1 is perturbed and the expression of LRP12 is measured. Determine whether LRP12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NF1 is perturbed and the expression of LRP12 is measured. Determine whether LRP12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97476
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V1G1 and then measure expression of PCNX1. Does this perturbation cause a significant change in PCNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP6V1G1 and then measure expression of PCNX1. Does this perturbation cause a significant change in PCNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9654
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBBP5 and examine the expression of GABARAPL2. Does perturbing RBBP5 lead to a significant change in GABARAPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBBP5 and examine the expression of GABARAPL2. Does perturbing RBBP5 lead to a significant change in GABARAPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74051
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and DNAJC3 expression is quantified. Does this perturbation result in a significant change in DNAJC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and DNAJC3 expression is quantified. Does this perturbation result in a significant change in DNAJC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100672
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS6 is perturbed and PLXNA1 expression is quantified. Does this perturbation result in a significant change in PLXNA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS6 is perturbed and PLXNA1 expression is quantified. Does this perturbation result in a significant change in PLXNA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27662
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOC5 is perturbed and the expression of PPP4R3B is measured. Determine whether PPP4R3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EXOC5 is perturbed and the expression of PPP4R3B is measured. Determine whether PPP4R3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102526
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR3D is associated with a significant change in BTBD10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR3D is associated with a significant change in BTBD10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104955
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAB4B is associated with a significant change in RAB11FIP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAB4B is associated with a significant change in RAB11FIP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61935
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBM42 is perturbed and DPP7 expression is observed. Does this perturbation lead to a significant difference in DPP7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBM42 is perturbed and DPP7 expression is observed. Does this perturbation lead to a significant difference in DPP7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68533
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LSM7 is perturbed and the expression of DDX27 is measured. Determine whether DDX27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LSM7 is perturbed and the expression of DDX27 is measured. Determine whether DDX27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93216
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPV3L1 and then measure expression of NFKBIB. Does this perturbation cause a significant change in NFKBIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPV3L1 and then measure expression of NFKBIB. Does this perturbation cause a significant change in NFKBIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60144
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS22 and examine the expression of PFDN4. Does perturbing MRPS22 lead to a significant change in PFDN4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS22 and examine the expression of PFDN4. Does perturbing MRPS22 lead to a significant change in PFDN4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67081
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC35A4 and monitor VAMP5 expression. Decide whether this perturbation leads to a significant alteration in VAMP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC35A4 and monitor VAMP5 expression. Decide whether this perturbation leads to a significant alteration in VAMP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120728
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHX37 is perturbed and SH3D21 expression is observed. Does this perturbation lead to a significant difference in SH3D21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHX37 is perturbed and SH3D21 expression is observed. Does this perturbation lead to a significant difference in SH3D21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91903
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYF2 and then measure expression of APAF1. Does this perturbation cause a significant change in APAF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYF2 and then measure expression of APAF1. Does this perturbation cause a significant change in APAF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24474
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCNM1 and then measure expression of SECISBP2L. Does this perturbation cause a significant change in SECISBP2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCNM1 and then measure expression of SECISBP2L. Does this perturbation cause a significant change in SECISBP2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57684
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ANAPC4 and monitor HEXIM1 expression. Decide whether this perturbation leads to a significant alteration in HEXIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ANAPC4 and monitor HEXIM1 expression. Decide whether this perturbation leads to a significant alteration in HEXIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29368
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SART1 is perturbed and GTF2IRD1 expression is measured. Determine whether GTF2IRD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SART1 is perturbed and GTF2IRD1 expression is measured. Determine whether GTF2IRD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6649
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UQCRC1 is perturbed and AP002360.1 expression is measured. Determine whether AP002360.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UQCRC1 is perturbed and AP002360.1 expression is measured. Determine whether AP002360.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31849
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CWF19L2, does the expression profile of GABPB1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CWF19L2, does the expression profile of GABPB1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87397
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBCC and then measure expression of KLHDC2. Does this perturbation cause a significant change in KLHDC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBCC and then measure expression of KLHDC2. Does this perturbation cause a significant change in KLHDC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110994
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GART is perturbed and CAVIN1 expression is measured. Determine whether CAVIN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GART is perturbed and CAVIN1 expression is measured. Determine whether CAVIN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10929
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb YARS and monitor PPP1R15A expression. Decide whether this perturbation leads to a significant alteration in PPP1R15A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YARS and monitor PPP1R15A expression. Decide whether this perturbation leads to a significant alteration in PPP1R15A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78428
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MALSU1, does the expression profile of MT-ATP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MALSU1, does the expression profile of MT-ATP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":857
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LETM1, does the expression profile of NAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LETM1, does the expression profile of NAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59787
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRK1 and examine the expression of ZNF280D. Does perturbing BRK1 lead to a significant change in ZNF280D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRK1 and examine the expression of ZNF280D. Does perturbing BRK1 lead to a significant change in ZNF280D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71861
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LONP1 is perturbed and LARP6 expression is measured. Determine whether LARP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LONP1 is perturbed and LARP6 expression is measured. Determine whether LARP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77179
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPP1R7 is perturbed and FBXW5 expression is observed. Does this perturbation lead to a significant difference in FBXW5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPP1R7 is perturbed and FBXW5 expression is observed. Does this perturbation lead to a significant difference in FBXW5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15023
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBPL1, does the expression profile of CCDC174 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBPL1, does the expression profile of CCDC174 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45437
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARS2 is perturbed and ITGA1 expression is observed. Does this perturbation lead to a significant difference in ITGA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARS2 is perturbed and ITGA1 expression is observed. Does this perturbation lead to a significant difference in ITGA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116063
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RNF168 and then measure expression of MRPL55. Does this perturbation cause a significant change in MRPL55 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RNF168 and then measure expression of MRPL55. Does this perturbation cause a significant change in MRPL55 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100964
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SSRP1 is perturbed and CSNK2A2 expression is measured. Determine whether CSNK2A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SSRP1 is perturbed and CSNK2A2 expression is measured. Determine whether CSNK2A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119039
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHEK1 is associated with a significant change in PEX26 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHEK1 is associated with a significant change in PEX26 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108285
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC5 and examine the expression of OSER1. Does perturbing THOC5 lead to a significant change in OSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC5 and examine the expression of OSER1. Does perturbing THOC5 lead to a significant change in OSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96281
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAE1 is perturbed and WDR55 expression is quantified. Does this perturbation result in a significant change in WDR55 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAE1 is perturbed and WDR55 expression is quantified. Does this perturbation result in a significant change in WDR55 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46982
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DESI1 is perturbed and PI4K2A expression is observed. Does this perturbation lead to a significant difference in PI4K2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DESI1 is perturbed and PI4K2A expression is observed. Does this perturbation lead to a significant difference in PI4K2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62533
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARIH1 is associated with a significant change in GLTP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARIH1 is associated with a significant change in GLTP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14195
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GTF2E1 and monitor PHB expression. Decide whether this perturbation leads to a significant alteration in PHB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GTF2E1 and monitor PHB expression. Decide whether this perturbation leads to a significant alteration in PHB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117398
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMARCC1 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMARCC1 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77944
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFB10, does the expression profile of G6PD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFB10, does the expression profile of G6PD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104757
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSG101 is perturbed and CNOT8 expression is observed. Does this perturbation lead to a significant difference in CNOT8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSG101 is perturbed and CNOT8 expression is observed. Does this perturbation lead to a significant difference in CNOT8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42193
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM2 is perturbed and the expression of MOSPD2 is measured. Does this perturbation cause a significant change in MOSPD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM2 is perturbed and the expression of MOSPD2 is measured. Does this perturbation cause a significant change in MOSPD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48840
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZWINT and examine the expression of MRPS10. Does perturbing ZWINT lead to a significant change in MRPS10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZWINT and examine the expression of MRPS10. Does perturbing ZWINT lead to a significant change in MRPS10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48961
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLRX3 is associated with a significant change in MRPL49 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLRX3 is associated with a significant change in MRPL49 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11545
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNF31 is associated with a significant change in FGF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNF31 is associated with a significant change in FGF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92935
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSTK is perturbed and KDELR3 expression is observed. Does this perturbation lead to a significant difference in KDELR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSTK is perturbed and KDELR3 expression is observed. Does this perturbation lead to a significant difference in KDELR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1853
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IST1 and examine the expression of MARCH3. Does perturbing IST1 lead to a significant change in MARCH3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IST1 and examine the expression of MARCH3. Does perturbing IST1 lead to a significant change in MARCH3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8441
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHAF1B, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHAF1B, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90717
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18A, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18A, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48037
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM7, does the expression profile of ANKRD50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM7, does the expression profile of ANKRD50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109667
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CD2BP2 is perturbed and CDK7 expression is quantified. Does this perturbation result in a significant change in CDK7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CD2BP2 is perturbed and CDK7 expression is quantified. Does this perturbation result in a significant change in CDK7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99792
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL17 is perturbed and ITPR1 expression is quantified. Does this perturbation result in a significant change in ITPR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL17 is perturbed and ITPR1 expression is quantified. Does this perturbation result in a significant change in ITPR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66852
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNRNPR and examine the expression of EIF2S2. Does perturbing HNRNPR lead to a significant change in EIF2S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNRNPR and examine the expression of EIF2S2. Does perturbing HNRNPR lead to a significant change in EIF2S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45791
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSBP and then measure expression of UBE2E1. Does this perturbation cause a significant change in UBE2E1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSBP and then measure expression of UBE2E1. Does this perturbation cause a significant change in UBE2E1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96314
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC5 is perturbed and BAZ2B expression is observed. Does this perturbation lead to a significant difference in BAZ2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC5 is perturbed and BAZ2B expression is observed. Does this perturbation lead to a significant difference in BAZ2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102493
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMG7 is perturbed and USP25 expression is quantified. Does this perturbation result in a significant change in USP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMG7 is perturbed and USP25 expression is quantified. Does this perturbation result in a significant change in USP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77532
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCFD1 is perturbed and SEC31A expression is measured. Determine whether SEC31A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCFD1 is perturbed and SEC31A expression is measured. Determine whether SEC31A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20309
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SETD2 is associated with a significant change in INPP5F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SETD2 is associated with a significant change in INPP5F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82105
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOP2 and examine the expression of ETFRF1. Does perturbing NOP2 lead to a significant change in ETFRF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOP2 and examine the expression of ETFRF1. Does perturbing NOP2 lead to a significant change in ETFRF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43361
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POP7 is perturbed and XRCC4 expression is measured. Determine whether XRCC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POP7 is perturbed and XRCC4 expression is measured. Determine whether XRCC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32889
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, REXO2 is perturbed and TENT5A expression is measured. Determine whether TENT5A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, REXO2 is perturbed and TENT5A expression is measured. Determine whether TENT5A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70149
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor CHD3 expression. Decide whether this perturbation leads to a significant alteration in CHD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor CHD3 expression. Decide whether this perturbation leads to a significant alteration in CHD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102278
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCKAP1 is perturbed and the expression of TLE1 is measured. Determine whether TLE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCKAP1 is perturbed and the expression of TLE1 is measured. Determine whether TLE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32936
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC7A5 is perturbed and SLC2A11 expression is measured. Determine whether SLC2A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC7A5 is perturbed and SLC2A11 expression is measured. Determine whether SLC2A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28919
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LAS1L, does the expression profile of LINC00662 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LAS1L, does the expression profile of LINC00662 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39067
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED27, does the expression profile of ARHGEF28 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED27, does the expression profile of ARHGEF28 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122747
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHODH, does the expression profile of GTF3C4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHODH, does the expression profile of GTF3C4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41127
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HMGCS1 and examine the expression of BMERB1. Does perturbing HMGCS1 lead to a significant change in BMERB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HMGCS1 and examine the expression of BMERB1. Does perturbing HMGCS1 lead to a significant change in BMERB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33481
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5ME is associated with a significant change in UQCC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5ME is associated with a significant change in UQCC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86125
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RRP15 is perturbed and the expression of JPX is measured. Does this perturbation cause a significant change in JPX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RRP15 is perturbed and the expression of JPX is measured. Does this perturbation cause a significant change in JPX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25210
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NAPA is perturbed and the expression of TPP1 is measured. Does this perturbation cause a significant change in TPP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NAPA is perturbed and the expression of TPP1 is measured. Does this perturbation cause a significant change in TPP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95950
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZFC3H1 and monitor DANCR expression. Decide whether this perturbation leads to a significant alteration in DANCR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZFC3H1 and monitor DANCR expression. Decide whether this perturbation leads to a significant alteration in DANCR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32368
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NSL1 and monitor CCNG2 expression. Decide whether this perturbation leads to a significant alteration in CCNG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NSL1 and monitor CCNG2 expression. Decide whether this perturbation leads to a significant alteration in CCNG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117508
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL42 is perturbed and TK2 expression is measured. Determine whether TK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL42 is perturbed and TK2 expression is measured. Determine whether TK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91549
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRCC1 is perturbed and CEP89 expression is quantified. Does this perturbation result in a significant change in CEP89 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRCC1 is perturbed and CEP89 expression is quantified. Does this perturbation result in a significant change in CEP89 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51302
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX7B and then measure expression of TMEM8A. Does this perturbation cause a significant change in TMEM8A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX7B and then measure expression of TMEM8A. Does this perturbation cause a significant change in TMEM8A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72414
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SMC4 and monitor SPAG9 expression. Decide whether this perturbation leads to a significant alteration in SPAG9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SMC4 and monitor SPAG9 expression. Decide whether this perturbation leads to a significant alteration in SPAG9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25398
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYBBP1A and examine the expression of GRINA. Does perturbing MYBBP1A lead to a significant change in GRINA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYBBP1A and examine the expression of GRINA. Does perturbing MYBBP1A lead to a significant change in GRINA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4441
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF3C5 and examine the expression of RPS28. Does perturbing GTF3C5 lead to a significant change in RPS28 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF3C5 and examine the expression of RPS28. Does perturbing GTF3C5 lead to a significant change in RPS28 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117451
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1D is perturbed and the expression of RAD1 is measured. Does this perturbation cause a significant change in RAD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1D is perturbed and the expression of RAD1 is measured. Does this perturbation cause a significant change in RAD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12670
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NFYC and examine the expression of ANGPT1. Does perturbing NFYC lead to a significant change in ANGPT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NFYC and examine the expression of ANGPT1. Does perturbing NFYC lead to a significant change in ANGPT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38301
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, E2F6 is perturbed and the expression of PREB is measured. Determine whether PREB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, E2F6 is perturbed and the expression of PREB is measured. Determine whether PREB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40906
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb E4F1 and monitor ST7 expression. Decide whether this perturbation leads to a significant alteration in ST7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb E4F1 and monitor ST7 expression. Decide whether this perturbation leads to a significant alteration in ST7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83788
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UQCRC1 is associated with a significant change in RING1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UQCRC1 is associated with a significant change in RING1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31835
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INO80 is associated with a significant change in FECH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INO80 is associated with a significant change in FECH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108075
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H18 and examine the expression of MAP2K3. Does perturbing ZC3H18 lead to a significant change in MAP2K3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H18 and examine the expression of MAP2K3. Does perturbing ZC3H18 lead to a significant change in MAP2K3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31881
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX54, does the expression profile of RAB10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX54, does the expression profile of RAB10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59747
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB17 is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB17 is perturbed and NUPR1 expression is measured. Determine whether NUPR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45179
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which WARS is perturbed and LINC02057 expression is observed. Does this perturbation lead to a significant difference in LINC02057 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which WARS is perturbed and LINC02057 expression is observed. Does this perturbation lead to a significant difference in LINC02057 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73543
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP14 is perturbed and the expression of CHPF is measured. Does this perturbation cause a significant change in CHPF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP14 is perturbed and the expression of CHPF is measured. Does this perturbation cause a significant change in CHPF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97740
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, METTL21A is perturbed and the expression of SGK3 is measured. Determine whether SGK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, METTL21A is perturbed and the expression of SGK3 is measured. Determine whether SGK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6906
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR8 is perturbed and RNMT expression is measured. Determine whether RNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR8 is perturbed and RNMT expression is measured. Determine whether RNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53969
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAMM41 is perturbed and MICU3 expression is measured. Determine whether MICU3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAMM41 is perturbed and MICU3 expression is measured. Determine whether MICU3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95729
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL27A is perturbed and the expression of SNHG19 is measured. Does this perturbation cause a significant change in SNHG19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL27A is perturbed and the expression of SNHG19 is measured. Does this perturbation cause a significant change in SNHG19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108450
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ERH is perturbed and the expression of AC016831.1 is measured. Determine whether AC016831.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ERH is perturbed and the expression of AC016831.1 is measured. Determine whether AC016831.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109456
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PHF12 is perturbed and ZNF622 expression is observed. Does this perturbation lead to a significant difference in ZNF622 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PHF12 is perturbed and ZNF622 expression is observed. Does this perturbation lead to a significant difference in ZNF622 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87113
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRRM2 and monitor DYNC2LI1 expression. Decide whether this perturbation leads to a significant alteration in DYNC2LI1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRRM2 and monitor DYNC2LI1 expression. Decide whether this perturbation leads to a significant alteration in DYNC2LI1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40998
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MCEE and then measure expression of ZDHHC17. Does this perturbation cause a significant change in ZDHHC17 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MCEE and then measure expression of ZDHHC17. Does this perturbation cause a significant change in ZDHHC17 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118544
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMB7 and monitor SLC66A1 expression. Decide whether this perturbation leads to a significant alteration in SLC66A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMB7 and monitor SLC66A1 expression. Decide whether this perturbation leads to a significant alteration in SLC66A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119768
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LARS2 and examine the expression of WDYHV1. Does perturbing LARS2 lead to a significant change in WDYHV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LARS2 and examine the expression of WDYHV1. Does perturbing LARS2 lead to a significant change in WDYHV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64391
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDC6 and examine the expression of TLCD3A. Does perturbing CDC6 lead to a significant change in TLCD3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDC6 and examine the expression of TLCD3A. Does perturbing CDC6 lead to a significant change in TLCD3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5691
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL13 is perturbed and SURF1 expression is quantified. Does this perturbation result in a significant change in SURF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL13 is perturbed and SURF1 expression is quantified. Does this perturbation result in a significant change in SURF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66712
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CENPA, does the expression profile of RAD50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CENPA, does the expression profile of RAD50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72107
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPLP0 is perturbed and the expression of NR3C1 is measured. Determine whether NR3C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPLP0 is perturbed and the expression of NR3C1 is measured. Determine whether NR3C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12356
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRRT, does the expression profile of DNASE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRRT, does the expression profile of DNASE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57857
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB1 and then measure expression of RSBN1L. Does this perturbation cause a significant change in RSBN1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB1 and then measure expression of RSBN1L. Does this perturbation cause a significant change in RSBN1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53534
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DYNLL2 and then measure expression of GPN2. Does this perturbation cause a significant change in GPN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DYNLL2 and then measure expression of GPN2. Does this perturbation cause a significant change in GPN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69284
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, H3F3A is perturbed and the expression of CENPO is measured. Does this perturbation cause a significant change in CENPO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, H3F3A is perturbed and the expression of CENPO is measured. Does this perturbation cause a significant change in CENPO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3160
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DROSHA and examine the expression of RAB38. Does perturbing DROSHA lead to a significant change in RAB38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DROSHA and examine the expression of RAB38. Does perturbing DROSHA lead to a significant change in RAB38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102441
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IWS1 is perturbed and COPZ2 expression is quantified. Does this perturbation result in a significant change in COPZ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IWS1 is perturbed and COPZ2 expression is quantified. Does this perturbation result in a significant change in COPZ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67852
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP23 and examine the expression of CFAP36. Does perturbing UTP23 lead to a significant change in CFAP36 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP23 and examine the expression of CFAP36. Does perturbing UTP23 lead to a significant change in CFAP36 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101721
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3H4 is associated with a significant change in ZCCHC24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3H4 is associated with a significant change in ZCCHC24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22535
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYRM4 is perturbed and the expression of CYFIP2 is measured. Determine whether CYFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYRM4 is perturbed and the expression of CYFIP2 is measured. Determine whether CYFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83836
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ABHD11, does the expression profile of SUGCT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ABHD11, does the expression profile of SUGCT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36747
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEP152 and monitor CPA4 expression. Decide whether this perturbation leads to a significant alteration in CPA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEP152 and monitor CPA4 expression. Decide whether this perturbation leads to a significant alteration in CPA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105258
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUBP2, does the expression profile of APP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUBP2, does the expression profile of APP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59017
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC3 is perturbed and RBP1 expression is measured. Determine whether RBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC3 is perturbed and RBP1 expression is measured. Determine whether RBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50439
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS7 and then measure expression of DCTN5. Does this perturbation cause a significant change in DCTN5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS7 and then measure expression of DCTN5. Does this perturbation cause a significant change in DCTN5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81394
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HEATR1, does the expression profile of IDS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HEATR1, does the expression profile of IDS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2157
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELP3 and then measure expression of SAT1. Does this perturbation cause a significant change in SAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELP3 and then measure expression of SAT1. Does this perturbation cause a significant change in SAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44034
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS17 is perturbed and MSH2 expression is quantified. Does this perturbation result in a significant change in MSH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS17 is perturbed and MSH2 expression is quantified. Does this perturbation result in a significant change in MSH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17172
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MPHOSPH6 and then measure expression of BCKDHB. Does this perturbation cause a significant change in BCKDHB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MPHOSPH6 and then measure expression of BCKDHB. Does this perturbation cause a significant change in BCKDHB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45674
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VPS41 is associated with a significant change in FAM155A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VPS41 is associated with a significant change in FAM155A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10405
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED19 is associated with a significant change in TRAPPC2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED19 is associated with a significant change in TRAPPC2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29545
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS8 is associated with a significant change in SELENOM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS8 is associated with a significant change in SELENOM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20255
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPA1 is associated with a significant change in GSDME expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPA1 is associated with a significant change in GSDME expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20195
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP10 is perturbed and NABP2 expression is measured. Determine whether NABP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP10 is perturbed and NABP2 expression is measured. Determine whether NABP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34689
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC6 and examine the expression of ATP6V0C. Does perturbing PSMC6 lead to a significant change in ATP6V0C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMC6 and examine the expression of ATP6V0C. Does perturbing PSMC6 lead to a significant change in ATP6V0C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102401
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAMLG, does the expression profile of COX4I1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAMLG, does the expression profile of COX4I1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2287
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP54, does the expression profile of LEPROT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP54, does the expression profile of LEPROT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121227
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL36A is perturbed and the expression of VSIR is measured. Determine whether VSIR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL36A is perturbed and the expression of VSIR is measured. Determine whether VSIR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86776
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARPC4 is perturbed and RELCH expression is quantified. Does this perturbation result in a significant change in RELCH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARPC4 is perturbed and RELCH expression is quantified. Does this perturbation result in a significant change in RELCH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20162
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF11 is perturbed and the expression of SAT1 is measured. Determine whether SAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF11 is perturbed and the expression of SAT1 is measured. Determine whether SAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15056
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT112 and examine the expression of PDLIM7. Does perturbing TRMT112 lead to a significant change in PDLIM7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT112 and examine the expression of PDLIM7. Does perturbing TRMT112 lead to a significant change in PDLIM7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2101
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEF2A and monitor CHPF2 expression. Decide whether this perturbation leads to a significant alteration in CHPF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEF2A and monitor CHPF2 expression. Decide whether this perturbation leads to a significant alteration in CHPF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62048
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD5 is perturbed and the expression of KDM4C is measured. Does this perturbation cause a significant change in KDM4C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD5 is perturbed and the expression of KDM4C is measured. Does this perturbation cause a significant change in KDM4C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":320
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HAUS1 and examine the expression of PGAP1. Does perturbing HAUS1 lead to a significant change in PGAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HAUS1 and examine the expression of PGAP1. Does perturbing HAUS1 lead to a significant change in PGAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102141
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC2 is perturbed and YBX1 expression is observed. Does this perturbation lead to a significant difference in YBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC2 is perturbed and YBX1 expression is observed. Does this perturbation lead to a significant difference in YBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47603
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PITRM1 is associated with a significant change in AASDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PITRM1 is associated with a significant change in AASDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73235
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC27 and then measure expression of LETMD1. Does this perturbation cause a significant change in LETMD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC27 and then measure expression of LETMD1. Does this perturbation cause a significant change in LETMD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14794
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC1 and then measure expression of CERT1. Does this perturbation cause a significant change in CERT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC1 and then measure expression of CERT1. Does this perturbation cause a significant change in CERT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56414
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELAC2 is perturbed and the expression of MORN4 is measured. Determine whether MORN4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELAC2 is perturbed and the expression of MORN4 is measured. Determine whether MORN4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56386
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IFITM2 and then measure expression of DYNC2LI1. Does this perturbation cause a significant change in DYNC2LI1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IFITM2 and then measure expression of DYNC2LI1. Does this perturbation cause a significant change in DYNC2LI1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122204
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFS5 is perturbed and the expression of FGFRL1 is measured. Does this perturbation cause a significant change in FGFRL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFS5 is perturbed and the expression of FGFRL1 is measured. Does this perturbation cause a significant change in FGFRL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2220
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF7, does the expression profile of MOK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF7, does the expression profile of MOK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115177
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNHIT2 is perturbed and LMBR1 expression is quantified. Does this perturbation result in a significant change in LMBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNHIT2 is perturbed and LMBR1 expression is quantified. Does this perturbation result in a significant change in LMBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30142
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL26, does the expression profile of CCNL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL26, does the expression profile of CCNL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16947
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of AGRN. Does this perturbation cause a significant change in AGRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of AGRN. Does this perturbation cause a significant change in AGRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32434
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL30 is perturbed and RBM45 expression is quantified. Does this perturbation result in a significant change in RBM45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL30 is perturbed and RBM45 expression is quantified. Does this perturbation result in a significant change in RBM45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36712
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VEZT is perturbed and UTP23 expression is measured. Determine whether UTP23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VEZT is perturbed and UTP23 expression is measured. Determine whether UTP23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67779
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR3H is perturbed and the expression of NREP is measured. Does this perturbation cause a significant change in NREP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR3H is perturbed and the expression of NREP is measured. Does this perturbation cause a significant change in NREP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54580
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHX16 is perturbed and NAT9 expression is quantified. Does this perturbation result in a significant change in NAT9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHX16 is perturbed and NAT9 expression is quantified. Does this perturbation result in a significant change in NAT9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91672
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOC1 is perturbed and QRSL1 expression is quantified. Does this perturbation result in a significant change in QRSL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOC1 is perturbed and QRSL1 expression is quantified. Does this perturbation result in a significant change in QRSL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100002
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CUL1 and then measure expression of BECN1. Does this perturbation cause a significant change in BECN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CUL1 and then measure expression of BECN1. Does this perturbation cause a significant change in BECN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75094
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF24 and examine the expression of SAMD9L. Does perturbing ZNF24 lead to a significant change in SAMD9L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF24 and examine the expression of SAMD9L. Does perturbing ZNF24 lead to a significant change in SAMD9L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116611
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP25 and examine the expression of SERINC3. Does perturbing UTP25 lead to a significant change in SERINC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UTP25 and examine the expression of SERINC3. Does perturbing UTP25 lead to a significant change in SERINC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54051
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARCN1 is perturbed and the expression of PILRB is measured. Does this perturbation cause a significant change in PILRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARCN1 is perturbed and the expression of PILRB is measured. Does this perturbation cause a significant change in PILRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48720
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBLL1 is associated with a significant change in PRCP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBLL1 is associated with a significant change in PRCP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95515
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PFDN1 is perturbed and ERLEC1 expression is observed. Does this perturbation lead to a significant difference in ERLEC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PFDN1 is perturbed and ERLEC1 expression is observed. Does this perturbation lead to a significant difference in ERLEC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28133
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCBP1 is perturbed and PLOD2 expression is quantified. Does this perturbation result in a significant change in PLOD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCBP1 is perturbed and PLOD2 expression is quantified. Does this perturbation result in a significant change in PLOD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62922
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5PD and examine the expression of ANGPTL4. Does perturbing ATP5PD lead to a significant change in ANGPTL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5PD and examine the expression of ANGPTL4. Does perturbing ATP5PD lead to a significant change in ANGPTL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69611
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANAPC11 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANAPC11 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76845
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SUMO2 is perturbed and SDCCAG8 expression is observed. Does this perturbation lead to a significant difference in SDCCAG8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SUMO2 is perturbed and SDCCAG8 expression is observed. Does this perturbation lead to a significant difference in SDCCAG8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35413
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1B2, does the expression profile of TBCK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1B2, does the expression profile of TBCK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60747
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TCOF1 is associated with a significant change in ATP6AP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TCOF1 is associated with a significant change in ATP6AP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83885
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID5B is perturbed and the expression of POLR3G is measured. Does this perturbation cause a significant change in POLR3G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID5B is perturbed and the expression of POLR3G is measured. Does this perturbation cause a significant change in POLR3G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67170
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRDM4 and monitor ARHGEF9 expression. Decide whether this perturbation leads to a significant alteration in ARHGEF9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRDM4 and monitor ARHGEF9 expression. Decide whether this perturbation leads to a significant alteration in ARHGEF9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107328
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ING3 and monitor BCS1L expression. Decide whether this perturbation leads to a significant alteration in BCS1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ING3 and monitor BCS1L expression. Decide whether this perturbation leads to a significant alteration in BCS1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47428
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRN3 is perturbed and the expression of BDNF is measured. Determine whether BDNF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRN3 is perturbed and the expression of BDNF is measured. Determine whether BDNF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49426
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL38 and examine the expression of FXR2. Does perturbing RPL38 lead to a significant change in FXR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL38 and examine the expression of FXR2. Does perturbing RPL38 lead to a significant change in FXR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52201
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PHB2 is perturbed and the expression of TRAF3IP1 is measured. Does this perturbation cause a significant change in TRAF3IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PHB2 is perturbed and the expression of TRAF3IP1 is measured. Does this perturbation cause a significant change in TRAF3IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63900
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HIST2H2AC and monitor ALAD expression. Decide whether this perturbation leads to a significant alteration in ALAD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HIST2H2AC and monitor ALAD expression. Decide whether this perturbation leads to a significant alteration in ALAD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112958
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TWNK is perturbed and the expression of MRPS21 is measured. Determine whether MRPS21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TWNK is perturbed and the expression of MRPS21 is measured. Determine whether MRPS21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26256
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VHL is perturbed and AREL1 expression is measured. Determine whether AREL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VHL is perturbed and AREL1 expression is measured. Determine whether AREL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40479
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AURKAIP1 is perturbed and the expression of PLD3 is measured. Does this perturbation cause a significant change in PLD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AURKAIP1 is perturbed and the expression of PLD3 is measured. Does this perturbation cause a significant change in PLD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65130
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCKAP1, does the expression profile of HLA-B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCKAP1, does the expression profile of HLA-B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32897
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1 and examine the expression of DESI1. Does perturbing GLB1 lead to a significant change in DESI1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1 and examine the expression of DESI1. Does perturbing GLB1 lead to a significant change in DESI1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101571
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCDC86 and monitor UBXN7 expression. Decide whether this perturbation leads to a significant alteration in UBXN7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCDC86 and monitor UBXN7 expression. Decide whether this perturbation leads to a significant alteration in UBXN7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108118
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MALSU1 is associated with a significant change in AC037198.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MALSU1 is associated with a significant change in AC037198.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":845
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPP1CB is associated with a significant change in ZMAT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPP1CB is associated with a significant change in ZMAT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122565
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFIP11 is perturbed and the expression of PRPF3 is measured. Determine whether PRPF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFIP11 is perturbed and the expression of PRPF3 is measured. Determine whether PRPF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117116
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL29 is perturbed and the expression of ACAA1 is measured. Determine whether ACAA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL29 is perturbed and the expression of ACAA1 is measured. Determine whether ACAA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107646
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS27A and then measure expression of ITSN1. Does this perturbation cause a significant change in ITSN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS27A and then measure expression of ITSN1. Does this perturbation cause a significant change in ITSN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101504
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPH3 is perturbed and PSPH expression is quantified. Does this perturbation result in a significant change in PSPH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPH3 is perturbed and PSPH expression is quantified. Does this perturbation result in a significant change in PSPH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46732
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTC1 and then measure expression of KBTBD2. Does this perturbation cause a significant change in KBTBD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTC1 and then measure expression of KBTBD2. Does this perturbation cause a significant change in KBTBD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38014
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUBP2 and then measure expression of TMEM115. Does this perturbation cause a significant change in TMEM115 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUBP2 and then measure expression of TMEM115. Does this perturbation cause a significant change in TMEM115 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59024
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDX42 is perturbed and LARP4B expression is observed. Does this perturbation lead to a significant difference in LARP4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDX42 is perturbed and LARP4B expression is observed. Does this perturbation lead to a significant difference in LARP4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24703
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CXXC1 is perturbed and RRP12 expression is quantified. Does this perturbation result in a significant change in RRP12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CXXC1 is perturbed and RRP12 expression is quantified. Does this perturbation result in a significant change in RRP12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67612
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BARD1, does the expression profile of RRAS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BARD1, does the expression profile of RRAS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122837
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPD2 is perturbed and SERINC2 expression is measured. Determine whether SERINC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPD2 is perturbed and SERINC2 expression is measured. Determine whether SERINC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107599
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAZ is perturbed and CIT expression is quantified. Does this perturbation result in a significant change in CIT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAZ is perturbed and CIT expression is quantified. Does this perturbation result in a significant change in CIT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1742
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PAK1IP1 is perturbed and PCSK1N expression is quantified. Does this perturbation result in a significant change in PCSK1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PAK1IP1 is perturbed and PCSK1N expression is quantified. Does this perturbation result in a significant change in PCSK1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71352
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMC3 is perturbed and HPS1 expression is observed. Does this perturbation lead to a significant difference in HPS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMC3 is perturbed and HPS1 expression is observed. Does this perturbation lead to a significant difference in HPS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41433
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2F1 and then measure expression of CYBRD1. Does this perturbation cause a significant change in CYBRD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF2F1 and then measure expression of CYBRD1. Does this perturbation cause a significant change in CYBRD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24024
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VHL is perturbed and AREL1 expression is quantified. Does this perturbation result in a significant change in AREL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VHL is perturbed and AREL1 expression is quantified. Does this perturbation result in a significant change in AREL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40472
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRCC6 and then measure expression of AC010642.2. Does this perturbation cause a significant change in AC010642.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRCC6 and then measure expression of AC010642.2. Does this perturbation cause a significant change in AC010642.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102894
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBA2 is perturbed and the expression of NCOA2 is measured. Determine whether NCOA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBA2 is perturbed and the expression of NCOA2 is measured. Determine whether NCOA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68966
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF31 is perturbed and NCOA7 expression is quantified. Does this perturbation result in a significant change in NCOA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF31 is perturbed and NCOA7 expression is quantified. Does this perturbation result in a significant change in NCOA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25992
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RNGTT is perturbed and the expression of NABP1 is measured. Does this perturbation cause a significant change in NABP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RNGTT is perturbed and the expression of NABP1 is measured. Does this perturbation cause a significant change in NABP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102960
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB7 is perturbed and the expression of MTOR is measured. Does this perturbation cause a significant change in MTOR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB7 is perturbed and the expression of MTOR is measured. Does this perturbation cause a significant change in MTOR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51460
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BUB1B is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BUB1B is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77816
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RINT1 is perturbed and the expression of YIPF2 is measured. Does this perturbation cause a significant change in YIPF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RINT1 is perturbed and the expression of YIPF2 is measured. Does this perturbation cause a significant change in YIPF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76730
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBM48 is associated with a significant change in NDST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBM48 is associated with a significant change in NDST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96365
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DYNLL2 and monitor CDC25B expression. Decide whether this perturbation leads to a significant alteration in CDC25B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DYNLL2 and monitor CDC25B expression. Decide whether this perturbation leads to a significant alteration in CDC25B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69238
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RNPS1 is perturbed and the expression of ANKRA2 is measured. Does this perturbation cause a significant change in ANKRA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RNPS1 is perturbed and the expression of ANKRA2 is measured. Does this perturbation cause a significant change in ANKRA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102570
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STRAP is perturbed and the expression of HOOK3 is measured. Does this perturbation cause a significant change in HOOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STRAP is perturbed and the expression of HOOK3 is measured. Does this perturbation cause a significant change in HOOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22370
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KATNB1 and examine the expression of JARID2. Does perturbing KATNB1 lead to a significant change in JARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KATNB1 and examine the expression of JARID2. Does perturbing KATNB1 lead to a significant change in JARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113951
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTPS1, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTPS1, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121997
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM33, does the expression profile of NUP35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM33, does the expression profile of NUP35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41197
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLNS1A is perturbed and the expression of AVL9 is measured. Does this perturbation cause a significant change in AVL9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLNS1A is perturbed and the expression of AVL9 is measured. Does this perturbation cause a significant change in AVL9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65840
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNOT3 and examine the expression of GOLPH3. Does perturbing CNOT3 lead to a significant change in GOLPH3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNOT3 and examine the expression of GOLPH3. Does perturbing CNOT3 lead to a significant change in GOLPH3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34211
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCR is perturbed and TIMM29 expression is quantified. Does this perturbation result in a significant change in TIMM29 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCR is perturbed and TIMM29 expression is quantified. Does this perturbation result in a significant change in TIMM29 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22862
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOP1 is perturbed and TMEM101 expression is measured. Determine whether TMEM101 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOP1 is perturbed and TMEM101 expression is measured. Determine whether TMEM101 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97069
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ORC6 is perturbed and P3H2 expression is measured. Determine whether P3H2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ORC6 is perturbed and P3H2 expression is measured. Determine whether P3H2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23329
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP1A1 is perturbed and IGF2BP1 expression is quantified. Does this perturbation result in a significant change in IGF2BP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP1A1 is perturbed and IGF2BP1 expression is quantified. Does this perturbation result in a significant change in IGF2BP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90072
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEN1 is perturbed and YWHAB expression is measured. Determine whether YWHAB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEN1 is perturbed and YWHAB expression is measured. Determine whether YWHAB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108939
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZFC3H1 and examine the expression of ALDH3A2. Does perturbing ZFC3H1 lead to a significant change in ALDH3A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZFC3H1 and examine the expression of ALDH3A2. Does perturbing ZFC3H1 lead to a significant change in ALDH3A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32381
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XPO5 is associated with a significant change in KPNA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XPO5 is associated with a significant change in KPNA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19055
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRAPPC4 is perturbed and KIAA0319L expression is quantified. Does this perturbation result in a significant change in KIAA0319L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRAPPC4 is perturbed and KIAA0319L expression is quantified. Does this perturbation result in a significant change in KIAA0319L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79862
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IPO13 is perturbed and the expression of YDJC is measured. Does this perturbation cause a significant change in YDJC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IPO13 is perturbed and the expression of YDJC is measured. Does this perturbation cause a significant change in YDJC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7870
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFA6 is associated with a significant change in AOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFA6 is associated with a significant change in AOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38805
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SUDS3 is perturbed and ABI1 expression is quantified. Does this perturbation result in a significant change in ABI1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SUDS3 is perturbed and ABI1 expression is quantified. Does this perturbation result in a significant change in ABI1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57452
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FBXO30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FBXO30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5575
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOL6 is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOL6 is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60425
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM5 is associated with a significant change in ZNF322 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MCM5 is associated with a significant change in ZNF322 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52885
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPTF is associated with a significant change in COQ4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPTF is associated with a significant change in COQ4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74135
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4A3 is perturbed and the expression of ZNF384 is measured. Does this perturbation cause a significant change in ZNF384 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4A3 is perturbed and the expression of ZNF384 is measured. Does this perturbation cause a significant change in ZNF384 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68720
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KDM2A and then measure expression of CFAP298. Does this perturbation cause a significant change in CFAP298 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KDM2A and then measure expression of CFAP298. Does this perturbation cause a significant change in CFAP298 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3564
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3F is perturbed and MXRA7 expression is quantified. Does this perturbation result in a significant change in MXRA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3F is perturbed and MXRA7 expression is quantified. Does this perturbation result in a significant change in MXRA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123492
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SDHA and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SDHA and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28828
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPR and then measure expression of CIR1. Does this perturbation cause a significant change in CIR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPR and then measure expression of CIR1. Does this perturbation cause a significant change in CIR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45754
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ABHD11 is perturbed and ROCK1 expression is quantified. Does this perturbation result in a significant change in ROCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ABHD11 is perturbed and ROCK1 expression is quantified. Does this perturbation result in a significant change in ROCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36762
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN2 and examine the expression of MDM2. Does perturbing XRN2 lead to a significant change in MDM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN2 and examine the expression of MDM2. Does perturbing XRN2 lead to a significant change in MDM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85261
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LDB1 is perturbed and the expression of AASS is measured. Does this perturbation cause a significant change in AASS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LDB1 is perturbed and the expression of AASS is measured. Does this perturbation cause a significant change in AASS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111050
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR55 and then measure expression of TNC. Does this perturbation cause a significant change in TNC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR55 and then measure expression of TNC. Does this perturbation cause a significant change in TNC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122604
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TPT1 and then measure expression of TMEM50B. Does this perturbation cause a significant change in TMEM50B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TPT1 and then measure expression of TMEM50B. Does this perturbation cause a significant change in TMEM50B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29034
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SKA3 is perturbed and the expression of SUGCT is measured. Does this perturbation cause a significant change in SUGCT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SKA3 is perturbed and the expression of SUGCT is measured. Does this perturbation cause a significant change in SUGCT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113110
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NFYB is perturbed and IFI27L2 expression is quantified. Does this perturbation result in a significant change in IFI27L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NFYB is perturbed and IFI27L2 expression is quantified. Does this perturbation result in a significant change in IFI27L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78612
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP152 and then measure expression of FCF1. Does this perturbation cause a significant change in FCF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP152 and then measure expression of FCF1. Does this perturbation cause a significant change in FCF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105274
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPS6 is perturbed and IDI1 expression is observed. Does this perturbation lead to a significant difference in IDI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPS6 is perturbed and IDI1 expression is observed. Does this perturbation lead to a significant difference in IDI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27673
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL17 and then measure expression of NDUFS2. Does this perturbation cause a significant change in NDUFS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL17 and then measure expression of NDUFS2. Does this perturbation cause a significant change in NDUFS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66864
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCT5 is perturbed and the expression of SELENOM is measured. Determine whether SELENOM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCT5 is perturbed and the expression of SELENOM is measured. Determine whether SELENOM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123616
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHMP7 and examine the expression of HSD17B11. Does perturbing CHMP7 lead to a significant change in HSD17B11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHMP7 and examine the expression of HSD17B11. Does perturbing CHMP7 lead to a significant change in HSD17B11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101831
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC3 is perturbed and the expression of IFT52 is measured. Determine whether IFT52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC3 is perturbed and the expression of IFT52 is measured. Determine whether IFT52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95146
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS11 and examine the expression of ZIM3. Does perturbing RPS11 lead to a significant change in ZIM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPS11 and examine the expression of ZIM3. Does perturbing RPS11 lead to a significant change in ZIM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77881
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, USPL1 is perturbed and the expression of CREB1 is measured. Does this perturbation cause a significant change in CREB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, USPL1 is perturbed and the expression of CREB1 is measured. Does this perturbation cause a significant change in CREB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97260
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V0C is perturbed and NNMT expression is measured. Determine whether NNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V0C is perturbed and NNMT expression is measured. Determine whether NNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42589
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM258 is perturbed and CISD2 expression is quantified. Does this perturbation result in a significant change in CISD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM258 is perturbed and CISD2 expression is quantified. Does this perturbation result in a significant change in CISD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16612
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDPK1 and examine the expression of AKAP9. Does perturbing PDPK1 lead to a significant change in AKAP9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDPK1 and examine the expression of AKAP9. Does perturbing PDPK1 lead to a significant change in AKAP9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81121
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPME1, does the expression profile of ANGPTL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPME1, does the expression profile of ANGPTL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31757
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COX17, does the expression profile of ACER3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COX17, does the expression profile of ACER3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12547
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCNL1 is perturbed and the expression of OGFOD1 is measured. Does this perturbation cause a significant change in OGFOD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCNL1 is perturbed and the expression of OGFOD1 is measured. Does this perturbation cause a significant change in OGFOD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107250
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHORDC1 is perturbed and SNHG14 expression is measured. Determine whether SNHG14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHORDC1 is perturbed and SNHG14 expression is measured. Determine whether SNHG14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46909
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FBXO42 is perturbed and the expression of EEPD1 is measured. Determine whether EEPD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FBXO42 is perturbed and the expression of EEPD1 is measured. Determine whether EEPD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1146
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TOP3A and monitor SLC30A5 expression. Decide whether this perturbation leads to a significant alteration in SLC30A5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TOP3A and monitor SLC30A5 expression. Decide whether this perturbation leads to a significant alteration in SLC30A5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103528
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PIK3C3 is associated with a significant change in TRIM8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PIK3C3 is associated with a significant change in TRIM8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76285
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2N is perturbed and GFER expression is quantified. Does this perturbation result in a significant change in GFER expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBE2N is perturbed and GFER expression is quantified. Does this perturbation result in a significant change in GFER expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64842
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM9 is associated with a significant change in TRMT61A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM9 is associated with a significant change in TRMT61A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74315
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAPZB is perturbed and NIPSNAP3A expression is observed. Does this perturbation lead to a significant difference in NIPSNAP3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAPZB is perturbed and NIPSNAP3A expression is observed. Does this perturbation lead to a significant difference in NIPSNAP3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21363
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USP14, does the expression profile of AC093673.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USP14, does the expression profile of AC093673.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31137
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBPL1 is perturbed and HCFC2 expression is quantified. Does this perturbation result in a significant change in HCFC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBPL1 is perturbed and HCFC2 expression is quantified. Does this perturbation result in a significant change in HCFC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45442
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RBBP4 and monitor ODF2 expression. Decide whether this perturbation leads to a significant alteration in ODF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RBBP4 and monitor ODF2 expression. Decide whether this perturbation leads to a significant alteration in ODF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11778
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CACNB3 is perturbed and the expression of CC2D1A is measured. Does this perturbation cause a significant change in CC2D1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CACNB3 is perturbed and the expression of CC2D1A is measured. Does this perturbation cause a significant change in CC2D1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33790
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCBP1 is perturbed and the expression of RANGRF is measured. Determine whether RANGRF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCBP1 is perturbed and the expression of RANGRF is measured. Determine whether RANGRF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62906
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPC is associated with a significant change in HOOK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPC is associated with a significant change in HOOK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119565
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTL6A is perturbed and EXT1 expression is measured. Determine whether EXT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTL6A is perturbed and EXT1 expression is measured. Determine whether EXT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109809
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL55, does the expression profile of MFN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL55, does the expression profile of MFN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79517
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNHIT3, does the expression profile of ZDHHC8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNHIT3, does the expression profile of ZDHHC8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48247
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B1 is perturbed and CCPG1 expression is observed. Does this perturbation lead to a significant difference in CCPG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B1 is perturbed and CCPG1 expression is observed. Does this perturbation lead to a significant difference in CCPG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79263
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3A2 and examine the expression of ORAI3. Does perturbing SF3A2 lead to a significant change in ORAI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3A2 and examine the expression of ORAI3. Does perturbing SF3A2 lead to a significant change in ORAI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8141
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB2 is perturbed and GMEB1 expression is observed. Does this perturbation lead to a significant difference in GMEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB2 is perturbed and GMEB1 expression is observed. Does this perturbation lead to a significant difference in GMEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68593
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of TNIP1 is measured. Does this perturbation cause a significant change in TNIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of TNIP1 is measured. Does this perturbation cause a significant change in TNIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18500
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of TNFRSF10D is measured. Determine whether TNFRSF10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of TNFRSF10D is measured. Determine whether TNFRSF10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13856
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLR3A is perturbed and XBP1 expression is measured. Determine whether XBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POLR3A is perturbed and XBP1 expression is measured. Determine whether XBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94159
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RAE1 and then measure expression of ETFDH. Does this perturbation cause a significant change in ETFDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RAE1 and then measure expression of ETFDH. Does this perturbation cause a significant change in ETFDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60694
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XAB2 is perturbed and FGFR1OP2 expression is measured. Determine whether FGFR1OP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XAB2 is perturbed and FGFR1OP2 expression is measured. Determine whether FGFR1OP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18579
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFA8, does the expression profile of ABL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFA8, does the expression profile of ABL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88917
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPAP1, does the expression profile of DCTN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPAP1, does the expression profile of DCTN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76447
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of REPS1 is measured. Does this perturbation cause a significant change in REPS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of REPS1 is measured. Does this perturbation cause a significant change in REPS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99340
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, N6AMT1 is perturbed and the expression of SMAP1 is measured. Does this perturbation cause a significant change in SMAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, N6AMT1 is perturbed and the expression of SMAP1 is measured. Does this perturbation cause a significant change in SMAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2480
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3B5 and examine the expression of SNHG32. Does perturbing SF3B5 lead to a significant change in SNHG32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SF3B5 and examine the expression of SNHG32. Does perturbing SF3B5 lead to a significant change in SNHG32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16051
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PARN and monitor PLOD3 expression. Decide whether this perturbation leads to a significant alteration in PLOD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PARN and monitor PLOD3 expression. Decide whether this perturbation leads to a significant alteration in PLOD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37318
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AQR is perturbed and TMCC3 expression is observed. Does this perturbation lead to a significant difference in TMCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AQR is perturbed and TMCC3 expression is observed. Does this perturbation lead to a significant difference in TMCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107183
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb N6AMT1 and monitor PPP6R3 expression. Decide whether this perturbation leads to a significant alteration in PPP6R3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb N6AMT1 and monitor PPP6R3 expression. Decide whether this perturbation leads to a significant alteration in PPP6R3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2438
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIPIN is perturbed and THOC5 expression is quantified. Does this perturbation result in a significant change in THOC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIPIN is perturbed and THOC5 expression is quantified. Does this perturbation result in a significant change in THOC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103892
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NFATC2IP is perturbed and TTC17 expression is measured. Determine whether TTC17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NFATC2IP is perturbed and TTC17 expression is measured. Determine whether TTC17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70039
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABCB7 is perturbed and the expression of KMT5B is measured. Determine whether KMT5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABCB7 is perturbed and the expression of KMT5B is measured. Determine whether KMT5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117846
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF4 is associated with a significant change in RPRD1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF4 is associated with a significant change in RPRD1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70405
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZRANB2 is perturbed and the expression of SUPV3L1 is measured. Determine whether SUPV3L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZRANB2 is perturbed and the expression of SUPV3L1 is measured. Determine whether SUPV3L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114726
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS6 is perturbed and CFAP36 expression is measured. Determine whether CFAP36 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS6 is perturbed and CFAP36 expression is measured. Determine whether CFAP36 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13439
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AGBL5 is associated with a significant change in AC027031.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AGBL5 is associated with a significant change in AC027031.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115955
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMG1 and then measure expression of ANAPC16. Does this perturbation cause a significant change in ANAPC16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SMG1 and then measure expression of ANAPC16. Does this perturbation cause a significant change in ANAPC16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32024
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PNN is perturbed and SLC17A5 expression is measured. Determine whether SLC17A5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PNN is perturbed and SLC17A5 expression is measured. Determine whether SLC17A5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62869
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A9 is associated with a significant change in RAB11B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A9 is associated with a significant change in RAB11B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86865
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARPC1B and monitor ARHGAP29 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARPC1B and monitor ARHGAP29 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58958
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TONSL is perturbed and MARK4 expression is measured. Determine whether MARK4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TONSL is perturbed and MARK4 expression is measured. Determine whether MARK4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114299
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS11, does the expression profile of CA9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS11, does the expression profile of CA9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8737
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDR3, does the expression profile of TFPI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDR3, does the expression profile of TFPI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79687
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PCF11 and then measure expression of AK1. Does this perturbation cause a significant change in AK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PCF11 and then measure expression of AK1. Does this perturbation cause a significant change in AK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86264
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YRDC is perturbed and RPIA expression is measured. Determine whether RPIA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YRDC is perturbed and RPIA expression is measured. Determine whether RPIA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18399
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHPS and examine the expression of RAPH1. Does perturbing DHPS lead to a significant change in RAPH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHPS and examine the expression of RAPH1. Does perturbing DHPS lead to a significant change in RAPH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10461
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of LURAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of LURAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11507
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPB is perturbed and the expression of KCNK6 is measured. Does this perturbation cause a significant change in KCNK6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPB is perturbed and the expression of KCNK6 is measured. Does this perturbation cause a significant change in KCNK6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105660
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS6 is perturbed and LRRC40 expression is observed. Does this perturbation lead to a significant difference in LRRC40 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS6 is perturbed and LRRC40 expression is observed. Does this perturbation lead to a significant difference in LRRC40 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13403
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IPO11, does the expression profile of CLTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IPO11, does the expression profile of CLTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65547
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HLA-C is perturbed and FKBP5 expression is observed. Does this perturbation lead to a significant difference in FKBP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HLA-C is perturbed and FKBP5 expression is observed. Does this perturbation lead to a significant difference in FKBP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22393
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF1B is perturbed and the expression of SDF2 is measured. Determine whether SDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF1B is perturbed and the expression of SDF2 is measured. Determine whether SDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92096
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PAXBP1 is perturbed and KIAA2026 expression is measured. Determine whether KIAA2026 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PAXBP1 is perturbed and KIAA2026 expression is measured. Determine whether KIAA2026 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35869
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SFSWAP and then measure expression of FLYWCH1. Does this perturbation cause a significant change in FLYWCH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SFSWAP and then measure expression of FLYWCH1. Does this perturbation cause a significant change in FLYWCH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84464
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLC2 is perturbed and SMG6 expression is quantified. Does this perturbation result in a significant change in SMG6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLC2 is perturbed and SMG6 expression is quantified. Does this perturbation result in a significant change in SMG6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20662
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAPZB and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAPZB and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21314
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SF3B5 and then measure expression of NADSYN1. Does this perturbation cause a significant change in NADSYN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SF3B5 and then measure expression of NADSYN1. Does this perturbation cause a significant change in NADSYN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16074
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MKRN1 is perturbed and PPIF expression is observed. Does this perturbation lead to a significant difference in PPIF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MKRN1 is perturbed and PPIF expression is observed. Does this perturbation lead to a significant difference in PPIF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58183
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ITGA11 expression is quantified. Does this perturbation result in a significant change in ITGA11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ITGA11 expression is quantified. Does this perturbation result in a significant change in ITGA11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103072
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDK11A and monitor DDX19A expression. Decide whether this perturbation leads to a significant alteration in DDX19A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDK11A and monitor DDX19A expression. Decide whether this perturbation leads to a significant alteration in DDX19A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48528
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COG8 and monitor RRAS expression. Decide whether this perturbation leads to a significant alteration in RRAS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COG8 and monitor RRAS expression. Decide whether this perturbation leads to a significant alteration in RRAS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15178
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NDUFA3 and examine the expression of SNHG8. Does perturbing NDUFA3 lead to a significant change in SNHG8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NDUFA3 and examine the expression of SNHG8. Does perturbing NDUFA3 lead to a significant change in SNHG8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36441
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR70 is perturbed and the expression of ASB3 is measured. Determine whether ASB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDR70 is perturbed and the expression of ASB3 is measured. Determine whether ASB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88896
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3E is perturbed and PIM3 expression is quantified. Does this perturbation result in a significant change in PIM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3E is perturbed and PIM3 expression is quantified. Does this perturbation result in a significant change in PIM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55972
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UQCRB and then measure expression of KRIT1. Does this perturbation cause a significant change in KRIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UQCRB and then measure expression of KRIT1. Does this perturbation cause a significant change in KRIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68124
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFB3 is perturbed and ZNF675 expression is quantified. Does this perturbation result in a significant change in ZNF675 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFB3 is perturbed and ZNF675 expression is quantified. Does this perturbation result in a significant change in ZNF675 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99582
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL4 is perturbed and STRADA expression is measured. Determine whether STRADA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL4 is perturbed and STRADA expression is measured. Determine whether STRADA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56999
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1143 is perturbed and SMC5 expression is quantified. Does this perturbation result in a significant change in SMC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1143 is perturbed and SMC5 expression is quantified. Does this perturbation result in a significant change in SMC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35042
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KPNB1 is perturbed and LAMB2 expression is quantified. Does this perturbation result in a significant change in LAMB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KPNB1 is perturbed and LAMB2 expression is quantified. Does this perturbation result in a significant change in LAMB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20472
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSNK1A1 is perturbed and HMG20B expression is measured. Determine whether HMG20B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSNK1A1 is perturbed and HMG20B expression is measured. Determine whether HMG20B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45859
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RAD17 is perturbed and the expression of GLRX is measured. Does this perturbation cause a significant change in GLRX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RAD17 is perturbed and the expression of GLRX is measured. Does this perturbation cause a significant change in GLRX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104300
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SUGP1 is perturbed and the expression of XYLT1 is measured. Determine whether XYLT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SUGP1 is perturbed and the expression of XYLT1 is measured. Determine whether XYLT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47686
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TXNL4A is perturbed and the expression of ANXA3 is measured. Determine whether ANXA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TXNL4A is perturbed and the expression of ANXA3 is measured. Determine whether ANXA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84336
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in ST7L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in ST7L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24095
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4G2 is perturbed and HSF2BP expression is measured. Determine whether HSF2BP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4G2 is perturbed and HSF2BP expression is measured. Determine whether HSF2BP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53449
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPP1R15B and monitor CHCHD6 expression. Decide whether this perturbation leads to a significant alteration in CHCHD6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPP1R15B and monitor CHCHD6 expression. Decide whether this perturbation leads to a significant alteration in CHCHD6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115108
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MFAP1 and monitor ZCCHC24 expression. Decide whether this perturbation leads to a significant alteration in ZCCHC24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MFAP1 and monitor ZCCHC24 expression. Decide whether this perturbation leads to a significant alteration in ZCCHC24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9558
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRF1 is associated with a significant change in SRGAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRF1 is associated with a significant change in SRGAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7885
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RNPC3 is perturbed and the expression of PPP1R14B-AS1 is measured. Does this perturbation cause a significant change in PPP1R14B-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RNPC3 is perturbed and the expression of PPP1R14B-AS1 is measured. Does this perturbation cause a significant change in PPP1R14B-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30500
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPK and then measure expression of MXI1. Does this perturbation cause a significant change in MXI1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPK and then measure expression of MXI1. Does this perturbation cause a significant change in MXI1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37444
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLTC is perturbed and GNPTAB expression is quantified. Does this perturbation result in a significant change in GNPTAB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLTC is perturbed and GNPTAB expression is quantified. Does this perturbation result in a significant change in GNPTAB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23372
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CACNB3 is perturbed and the expression of CC2D1A is measured. Determine whether CC2D1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CACNB3 is perturbed and the expression of CC2D1A is measured. Determine whether CC2D1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33796
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NOC4L is perturbed and CDC73 expression is measured. Determine whether CDC73 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NOC4L is perturbed and CDC73 expression is measured. Determine whether CDC73 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78139
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR18 and examine the expression of PGM3. Does perturbing WDR18 lead to a significant change in PGM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR18 and examine the expression of PGM3. Does perturbing WDR18 lead to a significant change in PGM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105941
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RCC1 and monitor SESN1 expression. Decide whether this perturbation leads to a significant alteration in SESN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RCC1 and monitor SESN1 expression. Decide whether this perturbation leads to a significant alteration in SESN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77408
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCTN4 is associated with a significant change in IBTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCTN4 is associated with a significant change in IBTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100245
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMG1, does the expression profile of DCPS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMG1, does the expression profile of DCPS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31997
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLC2 and examine the expression of PRRX1. Does perturbing KLC2 lead to a significant change in PRRX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLC2 and examine the expression of PRRX1. Does perturbing KLC2 lead to a significant change in PRRX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20681
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COASY and then measure expression of KATNB1. Does this perturbation cause a significant change in KATNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COASY and then measure expression of KATNB1. Does this perturbation cause a significant change in KATNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47664
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX11 is associated with a significant change in WWC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX11 is associated with a significant change in WWC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95035
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIS12 is perturbed and TERF2IP expression is observed. Does this perturbation lead to a significant difference in TERF2IP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIS12 is perturbed and TERF2IP expression is observed. Does this perturbation lead to a significant difference in TERF2IP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100873
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PNO1 is perturbed and the expression of PIP4K2B is measured. Does this perturbation cause a significant change in PIP4K2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PNO1 is perturbed and the expression of PIP4K2B is measured. Does this perturbation cause a significant change in PIP4K2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103830
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSNK1A1, does the expression profile of SNHG32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSNK1A1, does the expression profile of SNHG32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45817
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CENPI is perturbed and ME3 expression is measured. Determine whether ME3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CENPI is perturbed and ME3 expression is measured. Determine whether ME3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57349
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CMTR1 is perturbed and TBC1D5 expression is quantified. Does this perturbation result in a significant change in TBC1D5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CMTR1 is perturbed and TBC1D5 expression is quantified. Does this perturbation result in a significant change in TBC1D5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95262
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC2 and then measure expression of PITHD1. Does this perturbation cause a significant change in PITHD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC2 and then measure expression of PITHD1. Does this perturbation cause a significant change in PITHD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101214
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNRD1, does the expression profile of MYADM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNRD1, does the expression profile of MYADM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111417
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STRIP1 is perturbed and KRT18 expression is measured. Determine whether KRT18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STRIP1 is perturbed and KRT18 expression is measured. Determine whether KRT18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37549
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ERCC2 is perturbed and the expression of SNX3 is measured. Does this perturbation cause a significant change in SNX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ERCC2 is perturbed and the expression of SNX3 is measured. Does this perturbation cause a significant change in SNX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74430
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COG3 is perturbed and MPLKIP expression is observed. Does this perturbation lead to a significant difference in MPLKIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COG3 is perturbed and MPLKIP expression is observed. Does this perturbation lead to a significant difference in MPLKIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15253
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALG1 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALG1 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81619
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPE and examine the expression of SZT2. Does perturbing CENPE lead to a significant change in SZT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPE and examine the expression of SZT2. Does perturbing CENPE lead to a significant change in SZT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86541
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HPS5 is associated with a significant change in FAM126A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HPS5 is associated with a significant change in FAM126A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84025
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF23 is perturbed and RPS6KB2 expression is observed. Does this perturbation lead to a significant difference in RPS6KB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF23 is perturbed and RPS6KB2 expression is observed. Does this perturbation lead to a significant difference in RPS6KB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104713
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GUCD1 is perturbed and GPC1 expression is observed. Does this perturbation lead to a significant difference in GPC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GUCD1 is perturbed and GPC1 expression is observed. Does this perturbation lead to a significant difference in GPC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73373
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DMAP1 is associated with a significant change in PLAC9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DMAP1 is associated with a significant change in PLAC9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116705
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBE1 and examine the expression of SEMA5A. Does perturbing TUBE1 lead to a significant change in SEMA5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBE1 and examine the expression of SEMA5A. Does perturbing TUBE1 lead to a significant change in SEMA5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38361
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC115 is associated with a significant change in TCEA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCDC115 is associated with a significant change in TCEA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83205
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS18B and then measure expression of LYRM1. Does this perturbation cause a significant change in LYRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS18B and then measure expression of LYRM1. Does this perturbation cause a significant change in LYRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13704
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of FGF2. Does perturbing EIF2B2 lead to a significant change in FGF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of FGF2. Does perturbing EIF2B2 lead to a significant change in FGF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91371
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LONP1 and examine the expression of FHL2. Does perturbing LONP1 lead to a significant change in FHL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LONP1 and examine the expression of FHL2. Does perturbing LONP1 lead to a significant change in FHL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77191
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R10 is perturbed and the expression of SH3BGRL is measured. Determine whether SH3BGRL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R10 is perturbed and the expression of SH3BGRL is measured. Determine whether SH3BGRL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52266
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP6 is perturbed and the expression of TUBA4A is measured. Does this perturbation cause a significant change in TUBA4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP6 is perturbed and the expression of TUBA4A is measured. Does this perturbation cause a significant change in TUBA4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5220
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CACNB3 is perturbed and RPARP-AS1 expression is observed. Does this perturbation lead to a significant difference in RPARP-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CACNB3 is perturbed and RPARP-AS1 expression is observed. Does this perturbation lead to a significant difference in RPARP-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33833
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SMARCC1 is perturbed and PDLIM7 expression is measured. Determine whether PDLIM7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SMARCC1 is perturbed and PDLIM7 expression is measured. Determine whether PDLIM7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77989
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNRPD3 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNRPD3 and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24618
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PAF1 is perturbed and TSPAN14 expression is observed. Does this perturbation lead to a significant difference in TSPAN14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PAF1 is perturbed and TSPAN14 expression is observed. Does this perturbation lead to a significant difference in TSPAN14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15513
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COG3 is perturbed and PMEPA1 expression is quantified. Does this perturbation result in a significant change in PMEPA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COG3 is perturbed and PMEPA1 expression is quantified. Does this perturbation result in a significant change in PMEPA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15212
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF4A and examine the expression of ORC5. Does perturbing KIF4A lead to a significant change in ORC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF4A and examine the expression of ORC5. Does perturbing KIF4A lead to a significant change in ORC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55051
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LAMTOR3, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LAMTOR3, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79917
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HPS5 is perturbed and MAN2A1 expression is observed. Does this perturbation lead to a significant difference in MAN2A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HPS5 is perturbed and MAN2A1 expression is observed. Does this perturbation lead to a significant difference in MAN2A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84003
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5F1B is perturbed and VPS37A expression is quantified. Does this perturbation result in a significant change in VPS37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5F1B is perturbed and VPS37A expression is quantified. Does this perturbation result in a significant change in VPS37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49892
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP6V1E1 and monitor CEP44 expression. Decide whether this perturbation leads to a significant alteration in CEP44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP6V1E1 and monitor CEP44 expression. Decide whether this perturbation leads to a significant alteration in CEP44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112788
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC2 is perturbed and the expression of SMIM27 is measured. Determine whether SMIM27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC2 is perturbed and the expression of SMIM27 is measured. Determine whether SMIM27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68076
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of TANC2 is measured. Does this perturbation cause a significant change in TANC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of TANC2 is measured. Does this perturbation cause a significant change in TANC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99330
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOD2 is perturbed and OCRL expression is measured. Determine whether OCRL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOD2 is perturbed and OCRL expression is measured. Determine whether OCRL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87769
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZRANB2 is perturbed and MTMR1 expression is measured. Determine whether MTMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZRANB2 is perturbed and MTMR1 expression is measured. Determine whether MTMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114749
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX41 is perturbed and the expression of DCAF10 is measured. Determine whether DCAF10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX41 is perturbed and the expression of DCAF10 is measured. Determine whether DCAF10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104466
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNMT1 and examine the expression of ATP10D. Does perturbing DNMT1 lead to a significant change in ATP10D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNMT1 and examine the expression of ATP10D. Does perturbing DNMT1 lead to a significant change in ATP10D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100651
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LIMS1 is perturbed and the expression of FPGS is measured. Does this perturbation cause a significant change in FPGS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LIMS1 is perturbed and the expression of FPGS is measured. Does this perturbation cause a significant change in FPGS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":620
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ACTR10 and monitor JAG1 expression. Decide whether this perturbation leads to a significant alteration in JAG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ACTR10 and monitor JAG1 expression. Decide whether this perturbation leads to a significant alteration in JAG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26178
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF18 is associated with a significant change in HSBP1L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRPF18 is associated with a significant change in HSBP1L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45535
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AURKA and monitor RPGRIP1L expression. Decide whether this perturbation leads to a significant alteration in RPGRIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AURKA and monitor RPGRIP1L expression. Decide whether this perturbation leads to a significant alteration in RPGRIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113378
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCMF1 is associated with a significant change in PAXX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCMF1 is associated with a significant change in PAXX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85965
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR3H is associated with a significant change in PPP1R11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR3H is associated with a significant change in PPP1R11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54575
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CINP is perturbed and the expression of CCNG1 is measured. Does this perturbation cause a significant change in CCNG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CINP is perturbed and the expression of CCNG1 is measured. Does this perturbation cause a significant change in CCNG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97080
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLI4 is associated with a significant change in SDF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLI4 is associated with a significant change in SDF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19135
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MSL1 is perturbed and the expression of LTBP4 is measured. Does this perturbation cause a significant change in LTBP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MSL1 is perturbed and the expression of LTBP4 is measured. Does this perturbation cause a significant change in LTBP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112440
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MYBL2 and monitor MRPL1 expression. Decide whether this perturbation leads to a significant alteration in MRPL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MYBL2 and monitor MRPL1 expression. Decide whether this perturbation leads to a significant alteration in MRPL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7228
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TFDP1 is associated with a significant change in SLC35D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TFDP1 is associated with a significant change in SLC35D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56155
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DPAGT1 and examine the expression of SOD2. Does perturbing DPAGT1 lead to a significant change in SOD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DPAGT1 and examine the expression of SOD2. Does perturbing DPAGT1 lead to a significant change in SOD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91921
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUT is perturbed and WASHC2A expression is observed. Does this perturbation lead to a significant difference in WASHC2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUT is perturbed and WASHC2A expression is observed. Does this perturbation lead to a significant difference in WASHC2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103933
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KATNB1 and then measure expression of PLAT. Does this perturbation cause a significant change in PLAT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KATNB1 and then measure expression of PLAT. Does this perturbation cause a significant change in PLAT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113944
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MFAP1 is associated with a significant change in NT5DC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MFAP1 is associated with a significant change in NT5DC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9535
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALYREF is perturbed and ANXA6 expression is measured. Determine whether ANXA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALYREF is perturbed and ANXA6 expression is measured. Determine whether ANXA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40599
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPUSD3 is perturbed and the expression of GPC1 is measured. Does this perturbation cause a significant change in GPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPUSD3 is perturbed and the expression of GPC1 is measured. Does this perturbation cause a significant change in GPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64870
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISG20L2 is associated with a significant change in MYEOV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISG20L2 is associated with a significant change in MYEOV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112835
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TCERG1 and then measure expression of COPZ2. Does this perturbation cause a significant change in COPZ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TCERG1 and then measure expression of COPZ2. Does this perturbation cause a significant change in COPZ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40164
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CTU2 and examine the expression of SMIM29. Does perturbing CTU2 lead to a significant change in SMIM29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CTU2 and examine the expression of SMIM29. Does perturbing CTU2 lead to a significant change in SMIM29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93771
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POGLUT3 and then measure expression of PSMB7. Does this perturbation cause a significant change in PSMB7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POGLUT3 and then measure expression of PSMB7. Does this perturbation cause a significant change in PSMB7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24354
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb USP10 and examine the expression of GNAI1. Does perturbing USP10 lead to a significant change in GNAI1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb USP10 and examine the expression of GNAI1. Does perturbing USP10 lead to a significant change in GNAI1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34661
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KDM1A is perturbed and the expression of RAB22A is measured. Does this perturbation cause a significant change in RAB22A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KDM1A is perturbed and the expression of RAB22A is measured. Does this perturbation cause a significant change in RAB22A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41070
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP97 and then measure expression of PEX2. Does this perturbation cause a significant change in PEX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEP97 and then measure expression of PEX2. Does this perturbation cause a significant change in PEX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47144
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KDM6A is associated with a significant change in WWTR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KDM6A is associated with a significant change in WWTR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18195
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSME1 is perturbed and PPP6R2 expression is quantified. Does this perturbation result in a significant change in PPP6R2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSME1 is perturbed and PPP6R2 expression is quantified. Does this perturbation result in a significant change in PPP6R2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35252
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ENO1 and monitor LINC02802 expression. Decide whether this perturbation leads to a significant alteration in LINC02802 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ENO1 and monitor LINC02802 expression. Decide whether this perturbation leads to a significant alteration in LINC02802 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29838
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FXN is perturbed and GREM1 expression is quantified. Does this perturbation result in a significant change in GREM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FXN is perturbed and GREM1 expression is quantified. Does this perturbation result in a significant change in GREM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118092
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNK, does the expression profile of SAYSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNK, does the expression profile of SAYSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19607
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPC is associated with a significant change in PLBD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPC is associated with a significant change in PLBD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78885
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD2 is perturbed and the expression of ACTA2 is measured. Does this perturbation cause a significant change in ACTA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD2 is perturbed and the expression of ACTA2 is measured. Does this perturbation cause a significant change in ACTA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82070
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SHC1 and monitor GDF11 expression. Decide whether this perturbation leads to a significant alteration in GDF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SHC1 and monitor GDF11 expression. Decide whether this perturbation leads to a significant alteration in GDF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23128
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC17 is perturbed and CTDP1 expression is measured. Determine whether CTDP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC17 is perturbed and CTDP1 expression is measured. Determine whether CTDP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73819
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GOSR2, does the expression profile of TMUB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GOSR2, does the expression profile of TMUB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47547
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2R3C and then measure expression of LEPROTL1. Does this perturbation cause a significant change in LEPROTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2R3C and then measure expression of LEPROTL1. Does this perturbation cause a significant change in LEPROTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43624
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFA6 is perturbed and NOC3L expression is quantified. Does this perturbation result in a significant change in NOC3L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFA6 is perturbed and NOC3L expression is quantified. Does this perturbation result in a significant change in NOC3L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38792
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STAG2 is perturbed and ZFPM1 expression is observed. Does this perturbation lead to a significant difference in ZFPM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STAG2 is perturbed and ZFPM1 expression is observed. Does this perturbation lead to a significant difference in ZFPM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56033
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of CAPZB. Does perturbing CCT5 lead to a significant change in CAPZB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT5 and examine the expression of CAPZB. Does perturbing CCT5 lead to a significant change in CAPZB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123591
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS30 is perturbed and ZNF581 expression is measured. Determine whether ZNF581 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS30 is perturbed and ZNF581 expression is measured. Determine whether ZNF581 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29669
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNF168 is associated with a significant change in SEC16A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RNF168 is associated with a significant change in SEC16A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100955
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NLE1 is associated with a significant change in D2HGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NLE1 is associated with a significant change in D2HGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71245
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FYN and monitor ATP6V1B2 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1B2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FYN and monitor ATP6V1B2 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1B2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35628
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPS and then measure expression of GNB2. Does this perturbation cause a significant change in GNB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPS and then measure expression of GNB2. Does this perturbation cause a significant change in GNB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11934
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRNP40 is perturbed and the expression of PRKD2 is measured. Determine whether PRKD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRNP40 is perturbed and the expression of PRKD2 is measured. Determine whether PRKD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47806
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS51 is perturbed and SELENOM expression is measured. Determine whether SELENOM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS51 is perturbed and SELENOM expression is measured. Determine whether SELENOM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87019
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOP16 is perturbed and the expression of PTS is measured. Determine whether PTS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOP16 is perturbed and the expression of PTS is measured. Determine whether PTS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108666
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OPA1 is associated with a significant change in UBE3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OPA1 is associated with a significant change in UBE3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72695
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLE1, does the expression profile of DPP7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLE1, does the expression profile of DPP7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62407
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP6V1F is perturbed and the expression of MID1 is measured. Determine whether MID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP6V1F is perturbed and the expression of MID1 is measured. Determine whether MID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105216
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL2 is perturbed and RIT1 expression is measured. Determine whether RIT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL2 is perturbed and RIT1 expression is measured. Determine whether RIT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47459
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YPEL5 is perturbed and the expression of BTBD10 is measured. Determine whether BTBD10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YPEL5 is perturbed and the expression of BTBD10 is measured. Determine whether BTBD10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44356
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP160, does the expression profile of CLP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP160, does the expression profile of CLP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16877
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COQ4 is perturbed and the expression of SNHG5 is measured. Determine whether SNHG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COQ4 is perturbed and the expression of SNHG5 is measured. Determine whether SNHG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119216
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLD1 is perturbed and the expression of TUBB2A is measured. Determine whether TUBB2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLD1 is perturbed and the expression of TUBB2A is measured. Determine whether TUBB2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14656
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA2 is associated with a significant change in ECH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA2 is associated with a significant change in ECH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68935
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFAF3 is perturbed and BCL2L2 expression is quantified. Does this perturbation result in a significant change in BCL2L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFAF3 is perturbed and BCL2L2 expression is quantified. Does this perturbation result in a significant change in BCL2L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7992
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDX59 and monitor GADD45B expression. Decide whether this perturbation leads to a significant alteration in GADD45B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDX59 and monitor GADD45B expression. Decide whether this perturbation leads to a significant alteration in GADD45B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6438
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF207 and examine the expression of TSLP. Does perturbing ZNF207 lead to a significant change in TSLP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF207 and examine the expression of TSLP. Does perturbing ZNF207 lead to a significant change in TSLP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29731
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLASRP is associated with a significant change in PARP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLASRP is associated with a significant change in PARP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63995
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPE is perturbed and the expression of TBC1D9B is measured. Does this perturbation cause a significant change in TBC1D9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPE is perturbed and the expression of TBC1D9B is measured. Does this perturbation cause a significant change in TBC1D9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122090
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOP1 and then measure expression of ERCC2. Does this perturbation cause a significant change in ERCC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOP1 and then measure expression of ERCC2. Does this perturbation cause a significant change in ERCC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97014
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USP7 and then measure expression of MRPL17. Does this perturbation cause a significant change in MRPL17 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USP7 and then measure expression of MRPL17. Does this perturbation cause a significant change in MRPL17 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39394
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RFC2 is perturbed and NBDY expression is observed. Does this perturbation lead to a significant difference in NBDY expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RFC2 is perturbed and NBDY expression is observed. Does this perturbation lead to a significant difference in NBDY expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7253
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS6 is perturbed and SSB expression is quantified. Does this perturbation result in a significant change in SSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS6 is perturbed and SSB expression is quantified. Does this perturbation result in a significant change in SSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13452
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT2 and examine the expression of LMBR1. Does perturbing ZNHIT2 lead to a significant change in LMBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT2 and examine the expression of LMBR1. Does perturbing ZNHIT2 lead to a significant change in LMBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30141
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DYNC1I2 is perturbed and the expression of MBD5 is measured. Does this perturbation cause a significant change in MBD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DYNC1I2 is perturbed and the expression of MBD5 is measured. Does this perturbation cause a significant change in MBD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116110
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KRT8 and monitor EIF2D expression. Decide whether this perturbation leads to a significant alteration in EIF2D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KRT8 and monitor EIF2D expression. Decide whether this perturbation leads to a significant alteration in EIF2D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25118
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL13 is perturbed and the expression of ZNF574 is measured. Does this perturbation cause a significant change in ZNF574 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL13 is perturbed and the expression of ZNF574 is measured. Does this perturbation cause a significant change in ZNF574 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66750
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPU and monitor CIAO1 expression. Decide whether this perturbation leads to a significant alteration in CIAO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPU and monitor CIAO1 expression. Decide whether this perturbation leads to a significant alteration in CIAO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105108
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF4A is associated with a significant change in OGFOD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF4A is associated with a significant change in OGFOD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55065
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPL is perturbed and SMARCAL1 expression is measured. Determine whether SMARCAL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPL is perturbed and SMARCAL1 expression is measured. Determine whether SMARCAL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24609
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HARS2 and monitor FAM234A expression. Decide whether this perturbation leads to a significant alteration in FAM234A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HARS2 and monitor FAM234A expression. Decide whether this perturbation leads to a significant alteration in FAM234A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35708
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUT is perturbed and the expression of RARB is measured. Determine whether RARB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUT is perturbed and the expression of RARB is measured. Determine whether RARB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103916
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUDT21 is associated with a significant change in TRAPPC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUDT21 is associated with a significant change in TRAPPC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110025
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RFC1 is perturbed and the expression of KDELR1 is measured. Determine whether KDELR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RFC1 is perturbed and the expression of KDELR1 is measured. Determine whether KDELR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54846
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3B2 is associated with a significant change in CEBPZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3B2 is associated with a significant change in CEBPZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121745
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRSF2 is perturbed and MOSPD3 expression is quantified. Does this perturbation result in a significant change in MOSPD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRSF2 is perturbed and MOSPD3 expression is quantified. Does this perturbation result in a significant change in MOSPD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98072
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SS18L2 and examine the expression of ABHD10. Does perturbing SS18L2 lead to a significant change in ABHD10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SS18L2 and examine the expression of ABHD10. Does perturbing SS18L2 lead to a significant change in ABHD10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22741
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC8 is perturbed and NDUFAF1 expression is quantified. Does this perturbation result in a significant change in NDUFAF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC8 is perturbed and NDUFAF1 expression is quantified. Does this perturbation result in a significant change in NDUFAF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17192
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYRM4 is perturbed and NCAPH2 expression is measured. Determine whether NCAPH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYRM4 is perturbed and NCAPH2 expression is measured. Determine whether NCAPH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83859
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DGCR8 is perturbed and TMEM250 expression is measured. Determine whether TMEM250 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DGCR8 is perturbed and TMEM250 expression is measured. Determine whether TMEM250 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30129
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR1B is perturbed and TMEM132A expression is measured. Determine whether TMEM132A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR1B is perturbed and TMEM132A expression is measured. Determine whether TMEM132A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66299
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NLE1 is perturbed and the expression of CDC42EP3 is measured. Does this perturbation cause a significant change in CDC42EP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NLE1 is perturbed and the expression of CDC42EP3 is measured. Does this perturbation cause a significant change in CDC42EP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71230
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NACA is perturbed and EPB41L4A-AS1 expression is measured. Determine whether EPB41L4A-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NACA is perturbed and EPB41L4A-AS1 expression is measured. Determine whether EPB41L4A-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67919
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NFYB is perturbed and the expression of PTPN23 is measured. Determine whether PTPN23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NFYB is perturbed and the expression of PTPN23 is measured. Determine whether PTPN23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78626
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTK2 and examine the expression of USE1. Does perturbing PTK2 lead to a significant change in USE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTK2 and examine the expression of USE1. Does perturbing PTK2 lead to a significant change in USE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11321
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TACC3 is perturbed and the expression of HSPA5 is measured. Does this perturbation cause a significant change in HSPA5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TACC3 is perturbed and the expression of HSPA5 is measured. Does this perturbation cause a significant change in HSPA5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14890
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL34 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL34 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28625
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP85 is perturbed and the expression of HIST3H2A is measured. Determine whether HIST3H2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP85 is perturbed and the expression of HIST3H2A is measured. Determine whether HIST3H2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18806
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF3C6 is associated with a significant change in IFRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GTF3C6 is associated with a significant change in IFRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64445
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNOT3 is perturbed and the expression of COPS7A is measured. Does this perturbation cause a significant change in COPS7A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNOT3 is perturbed and the expression of COPS7A is measured. Does this perturbation cause a significant change in COPS7A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34260
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COA5 is perturbed and the expression of BLOC1S5 is measured. Determine whether BLOC1S5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COA5 is perturbed and the expression of BLOC1S5 is measured. Determine whether BLOC1S5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84526
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABCB7 is perturbed and the expression of TGFB2 is measured. Determine whether TGFB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABCB7 is perturbed and the expression of TGFB2 is measured. Determine whether TGFB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117876
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3A is perturbed and IL1B expression is quantified. Does this perturbation result in a significant change in IL1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF3A is perturbed and IL1B expression is quantified. Does this perturbation result in a significant change in IL1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51052
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TPT1 is perturbed and the expression of SCD is measured. Determine whether SCD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TPT1 is perturbed and the expression of SCD is measured. Determine whether SCD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29006
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TCOF1 is perturbed and IL1B expression is observed. Does this perturbation lead to a significant difference in IL1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TCOF1 is perturbed and IL1B expression is observed. Does this perturbation lead to a significant difference in IL1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83923
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPS4 is perturbed and RECK expression is observed. Does this perturbation lead to a significant difference in RECK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPS4 is perturbed and RECK expression is observed. Does this perturbation lead to a significant difference in RECK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119703
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AAAS and then measure expression of TMEM134. Does this perturbation cause a significant change in TMEM134 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AAAS and then measure expression of TMEM134. Does this perturbation cause a significant change in TMEM134 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88184
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NR2C2AP is perturbed and ADAM19 expression is quantified. Does this perturbation result in a significant change in ADAM19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NR2C2AP is perturbed and ADAM19 expression is quantified. Does this perturbation result in a significant change in ADAM19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22932
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCEE is perturbed and BBIP1 expression is measured. Determine whether BBIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCEE is perturbed and BBIP1 expression is measured. Determine whether BBIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118539
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL10 is perturbed and CSNK2A2 expression is observed. Does this perturbation lead to a significant difference in CSNK2A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL10 is perturbed and CSNK2A2 expression is observed. Does this perturbation lead to a significant difference in CSNK2A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42803
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DICER1 and monitor ADAM12 expression. Decide whether this perturbation leads to a significant alteration in ADAM12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DICER1 and monitor ADAM12 expression. Decide whether this perturbation leads to a significant alteration in ADAM12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77778
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DPY19L4 is associated with a significant change in GPATCH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DPY19L4 is associated with a significant change in GPATCH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36665
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VBP1 is associated with a significant change in C11orf49 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VBP1 is associated with a significant change in C11orf49 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75495
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1E1 is perturbed and the expression of TM7SF2 is measured. Does this perturbation cause a significant change in TM7SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6V1E1 is perturbed and the expression of TM7SF2 is measured. Does this perturbation cause a significant change in TM7SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112730
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TFAM and monitor RBM18 expression. Decide whether this perturbation leads to a significant alteration in RBM18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TFAM and monitor RBM18 expression. Decide whether this perturbation leads to a significant alteration in RBM18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1278
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCF11 is perturbed and the expression of FGD4 is measured. Determine whether FGD4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCF11 is perturbed and the expression of FGD4 is measured. Determine whether FGD4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86246
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STARD7 is associated with a significant change in HCFC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STARD7 is associated with a significant change in HCFC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93475
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CINP is associated with a significant change in NRBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CINP is associated with a significant change in NRBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97115
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC9 and monitor VPS39 expression. Decide whether this perturbation leads to a significant alteration in VPS39 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC9 and monitor VPS39 expression. Decide whether this perturbation leads to a significant alteration in VPS39 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58218
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DSN1 and examine the expression of TRAFD1. Does perturbing DSN1 lead to a significant change in TRAFD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DSN1 and examine the expression of TRAFD1. Does perturbing DSN1 lead to a significant change in TRAFD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96681
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNOT3 and then measure expression of COPS7A. Does this perturbation cause a significant change in COPS7A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNOT3 and then measure expression of COPS7A. Does this perturbation cause a significant change in COPS7A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34264
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of EPHX1. Does perturbing HSPA9 lead to a significant change in EPHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of EPHX1. Does perturbing HSPA9 lead to a significant change in EPHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5531
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PET117 and monitor COPE expression. Decide whether this perturbation leads to a significant alteration in COPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PET117 and monitor COPE expression. Decide whether this perturbation leads to a significant alteration in COPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100288
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRMT5 is associated with a significant change in RAB30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRMT5 is associated with a significant change in RAB30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39945
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM199 is perturbed and MICU1 expression is measured. Determine whether MICU1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM199 is perturbed and MICU1 expression is measured. Determine whether MICU1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9869
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of CHCHD3 is measured. Determine whether CHCHD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of CHCHD3 is measured. Determine whether CHCHD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118916
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RCOR1 and monitor ARRB2 expression. Decide whether this perturbation leads to a significant alteration in ARRB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RCOR1 and monitor ARRB2 expression. Decide whether this perturbation leads to a significant alteration in ARRB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36248
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NAF1 is perturbed and ANXA3 expression is observed. Does this perturbation lead to a significant difference in ANXA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NAF1 is perturbed and ANXA3 expression is observed. Does this perturbation lead to a significant difference in ANXA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93873
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPA1 is perturbed and CYB5R1 expression is quantified. Does this perturbation result in a significant change in CYB5R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPA1 is perturbed and CYB5R1 expression is quantified. Does this perturbation result in a significant change in CYB5R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19222
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CIAO1 and monitor SHARPIN expression. Decide whether this perturbation leads to a significant alteration in SHARPIN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CIAO1 and monitor SHARPIN expression. Decide whether this perturbation leads to a significant alteration in SHARPIN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9728
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS11 is perturbed and RNF20 expression is quantified. Does this perturbation result in a significant change in RNF20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS11 is perturbed and RNF20 expression is quantified. Does this perturbation result in a significant change in RNF20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77912
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SHOC2 is perturbed and RPS8 expression is observed. Does this perturbation lead to a significant difference in RPS8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SHOC2 is perturbed and RPS8 expression is observed. Does this perturbation lead to a significant difference in RPS8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103353
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCP110 is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCP110 is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9232
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERAL1 is associated with a significant change in SSH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERAL1 is associated with a significant change in SSH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65615
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF8 is perturbed and the expression of SDHD is measured. Determine whether SDHD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF8 is perturbed and the expression of SDHD is measured. Determine whether SDHD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68176
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMA2 is associated with a significant change in PCNX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMA2 is associated with a significant change in PCNX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115405
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSG101 is perturbed and CRIP2 expression is quantified. Does this perturbation result in a significant change in CRIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSG101 is perturbed and CRIP2 expression is quantified. Does this perturbation result in a significant change in CRIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42152
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35G2 is perturbed and LARS2 expression is observed. Does this perturbation lead to a significant difference in LARS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35G2 is perturbed and LARS2 expression is observed. Does this perturbation lead to a significant difference in LARS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57603
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3A is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3A is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51035
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UTP3 is perturbed and EIF4B expression is observed. Does this perturbation lead to a significant difference in EIF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UTP3 is perturbed and EIF4B expression is observed. Does this perturbation lead to a significant difference in EIF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108983
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSFM and examine the expression of DHODH. Does perturbing TSFM lead to a significant change in DHODH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSFM and examine the expression of DHODH. Does perturbing TSFM lead to a significant change in DHODH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52531
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBM12 is perturbed and the expression of SMPD1 is measured. Determine whether SMPD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RBM12 is perturbed and the expression of SMPD1 is measured. Determine whether SMPD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21306
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRNT1, does the expression profile of CTTNBP2NL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRNT1, does the expression profile of CTTNBP2NL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2047
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of SERPINE2. Does this perturbation cause a significant change in SERPINE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of SERPINE2. Does this perturbation cause a significant change in SERPINE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107694
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TADA2B is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TADA2B is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33513
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RAD17 is perturbed and TMEM161B-AS1 expression is measured. Determine whether TMEM161B-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RAD17 is perturbed and TMEM161B-AS1 expression is measured. Determine whether TMEM161B-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104319
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RABGGTA and monitor ZNF574 expression. Decide whether this perturbation leads to a significant alteration in ZNF574 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RABGGTA and monitor ZNF574 expression. Decide whether this perturbation leads to a significant alteration in ZNF574 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61178
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAGOH is perturbed and CLSTN2 expression is observed. Does this perturbation lead to a significant difference in CLSTN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAGOH is perturbed and CLSTN2 expression is observed. Does this perturbation lead to a significant difference in CLSTN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72893
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MSRB1 is associated with a significant change in TMED5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MSRB1 is associated with a significant change in TMED5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40235
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPIE is perturbed and TMEM14A expression is quantified. Does this perturbation result in a significant change in TMEM14A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPIE is perturbed and TMEM14A expression is quantified. Does this perturbation result in a significant change in TMEM14A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116852
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EMC4 is perturbed and the expression of ME1 is measured. Determine whether ME1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EMC4 is perturbed and the expression of ME1 is measured. Determine whether ME1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60896
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H18 and examine the expression of MTRNR2L12. Does perturbing ZC3H18 lead to a significant change in MTRNR2L12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3H18 and examine the expression of MTRNR2L12. Does perturbing ZC3H18 lead to a significant change in MTRNR2L12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31911
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOL9 and examine the expression of PUS1. Does perturbing NOL9 lead to a significant change in PUS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NOL9 and examine the expression of PUS1. Does perturbing NOL9 lead to a significant change in PUS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4081
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSEN34 is perturbed and C15orf61 expression is measured. Determine whether C15orf61 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSEN34 is perturbed and C15orf61 expression is measured. Determine whether C15orf61 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18989
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP19 and monitor OS9 expression. Decide whether this perturbation leads to a significant alteration in OS9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP19 and monitor OS9 expression. Decide whether this perturbation leads to a significant alteration in OS9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34758
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TOMM20 is perturbed and ABI1 expression is observed. Does this perturbation lead to a significant difference in ABI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TOMM20 is perturbed and ABI1 expression is observed. Does this perturbation lead to a significant difference in ABI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14913
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UTP25 is perturbed and BBS2 expression is measured. Determine whether BBS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UTP25 is perturbed and BBS2 expression is measured. Determine whether BBS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54069
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCT2, does the expression profile of ZNF217 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCT2, does the expression profile of ZNF217 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98967
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METAP2 is perturbed and REST expression is quantified. Does this perturbation result in a significant change in REST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, METAP2 is perturbed and REST expression is quantified. Does this perturbation result in a significant change in REST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122942
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CPNE7 and then measure expression of MCC. Does this perturbation cause a significant change in MCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CPNE7 and then measure expression of MCC. Does this perturbation cause a significant change in MCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17774
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDHAF2 is perturbed and CDC5L expression is observed. Does this perturbation lead to a significant difference in CDC5L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDHAF2 is perturbed and CDC5L expression is observed. Does this perturbation lead to a significant difference in CDC5L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28263
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNF8 is associated with a significant change in CXCL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNF8 is associated with a significant change in CXCL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72965
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCM2 is perturbed and GPRC5A expression is measured. Determine whether GPRC5A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCM2 is perturbed and GPRC5A expression is measured. Determine whether GPRC5A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63299
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FGFR1OP and monitor RND3 expression. Decide whether this perturbation leads to a significant alteration in RND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FGFR1OP and monitor RND3 expression. Decide whether this perturbation leads to a significant alteration in RND3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95458
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IMPA2 and monitor MOSPD1 expression. Decide whether this perturbation leads to a significant alteration in MOSPD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IMPA2 and monitor MOSPD1 expression. Decide whether this perturbation leads to a significant alteration in MOSPD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74768
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B5 is associated with a significant change in SNX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B5 is associated with a significant change in SNX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52005
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RSF1. Does perturbing EIF2S1 lead to a significant change in RSF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RSF1. Does perturbing EIF2S1 lead to a significant change in RSF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37801
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BUB3 is perturbed and the expression of DNAJB4 is measured. Does this perturbation cause a significant change in DNAJB4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BUB3 is perturbed and the expression of DNAJB4 is measured. Does this perturbation cause a significant change in DNAJB4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42110
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLNS1A is perturbed and the expression of RIN2 is measured. Determine whether RIN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLNS1A is perturbed and the expression of RIN2 is measured. Determine whether RIN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65826
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAX and monitor SNAPC1 expression. Decide whether this perturbation leads to a significant alteration in SNAPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAX and monitor SNAPC1 expression. Decide whether this perturbation leads to a significant alteration in SNAPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95888
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R11 is perturbed and the expression of KAT6B is measured. Does this perturbation cause a significant change in KAT6B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R11 is perturbed and the expression of KAT6B is measured. Does this perturbation cause a significant change in KAT6B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109370
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CTCF is associated with a significant change in SLC35A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CTCF is associated with a significant change in SLC35A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123225
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PI4KA, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PI4KA, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49007
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX3X, does the expression profile of SNX21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX3X, does the expression profile of SNX21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41957
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPK and examine the expression of STK4. Does perturbing CENPK lead to a significant change in STK4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPK and examine the expression of STK4. Does perturbing CENPK lead to a significant change in STK4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26291
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEP97 is perturbed and ZMYM2 expression is measured. Determine whether ZMYM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEP97 is perturbed and ZMYM2 expression is measured. Determine whether ZMYM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47169
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NARS2, does the expression profile of ANKZF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NARS2, does the expression profile of ANKZF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26587
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PMPCA is perturbed and the expression of GADD45A is measured. Does this perturbation cause a significant change in GADD45A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PMPCA is perturbed and the expression of GADD45A is measured. Does this perturbation cause a significant change in GADD45A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72010
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS28 is perturbed and SEM1 expression is observed. Does this perturbation lead to a significant difference in SEM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS28 is perturbed and SEM1 expression is observed. Does this perturbation lead to a significant difference in SEM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93453
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS17 is associated with a significant change in MSH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS17 is associated with a significant change in MSH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17175
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CWC15 and examine the expression of AOPEP. Does perturbing CWC15 lead to a significant change in AOPEP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CWC15 and examine the expression of AOPEP. Does perturbing CWC15 lead to a significant change in AOPEP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78081
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NUP85 is perturbed and XPC expression is measured. Determine whether XPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NUP85 is perturbed and XPC expression is measured. Determine whether XPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18819
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMB7 is perturbed and the expression of TNNT1 is measured. Does this perturbation cause a significant change in TNNT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMB7 is perturbed and the expression of TNNT1 is measured. Does this perturbation cause a significant change in TNNT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119780
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and RCOR1 expression is observed. Does this perturbation lead to a significant difference in RCOR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and RCOR1 expression is observed. Does this perturbation lead to a significant difference in RCOR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82823
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAPC5 is perturbed and the expression of SSR4 is measured. Does this perturbation cause a significant change in SSR4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAPC5 is perturbed and the expression of SSR4 is measured. Does this perturbation cause a significant change in SSR4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42020
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD11 and examine the expression of NXPE3. Does perturbing PSMD11 lead to a significant change in NXPE3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD11 and examine the expression of NXPE3. Does perturbing PSMD11 lead to a significant change in NXPE3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94861
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARRB2 and monitor ZNF609 expression. Decide whether this perturbation leads to a significant alteration in ZNF609 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARRB2 and monitor ZNF609 expression. Decide whether this perturbation leads to a significant alteration in ZNF609 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106428
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RAN is perturbed and the expression of CPSF4 is measured. Does this perturbation cause a significant change in CPSF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RAN is perturbed and the expression of CPSF4 is measured. Does this perturbation cause a significant change in CPSF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28180
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALG14 is perturbed and KAT6B expression is measured. Determine whether KAT6B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ALG14 is perturbed and KAT6B expression is measured. Determine whether KAT6B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97569
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AFG3L2 and then measure expression of TMEM179B. Does this perturbation cause a significant change in TMEM179B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AFG3L2 and then measure expression of TMEM179B. Does this perturbation cause a significant change in TMEM179B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87984
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD6 is perturbed and the expression of BRD1 is measured. Determine whether BRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD6 is perturbed and the expression of BRD1 is measured. Determine whether BRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78716
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and EMC3 expression is quantified. Does this perturbation result in a significant change in EMC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and EMC3 expression is quantified. Does this perturbation result in a significant change in EMC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90492
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L1 is associated with a significant change in CEP83 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L1 is associated with a significant change in CEP83 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7475
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBR4 is perturbed and SUGP2 expression is observed. Does this perturbation lead to a significant difference in SUGP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBR4 is perturbed and SUGP2 expression is observed. Does this perturbation lead to a significant difference in SUGP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4283
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB4A is perturbed and the expression of CCDC174 is measured. Determine whether CCDC174 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB4A is perturbed and the expression of CCDC174 is measured. Determine whether CCDC174 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46106
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRIAP1 is perturbed and the expression of AKIRIN1 is measured. Determine whether AKIRIN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRIAP1 is perturbed and the expression of AKIRIN1 is measured. Determine whether AKIRIN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110176
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4G2 is associated with a significant change in RAP2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4G2 is associated with a significant change in RAP2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53435
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL50 is perturbed and BHLHE40 expression is measured. Determine whether BHLHE40 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL50 is perturbed and BHLHE40 expression is measured. Determine whether BHLHE40 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87499
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNM2 is perturbed and CZIB expression is quantified. Does this perturbation result in a significant change in CZIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNM2 is perturbed and CZIB expression is quantified. Does this perturbation result in a significant change in CZIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69442
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor SYF2 expression. Decide whether this perturbation leads to a significant alteration in SYF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor SYF2 expression. Decide whether this perturbation leads to a significant alteration in SYF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45578
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KANSL3 is perturbed and the expression of GIT1 is measured. Does this perturbation cause a significant change in GIT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KANSL3 is perturbed and the expression of GIT1 is measured. Does this perturbation cause a significant change in GIT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93990
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2H and examine the expression of AKT2. Does perturbing UBE2H lead to a significant change in AKT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2H and examine the expression of AKT2. Does perturbing UBE2H lead to a significant change in AKT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30621
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ESYT1 is perturbed and the expression of INSIG2 is measured. Determine whether INSIG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ESYT1 is perturbed and the expression of INSIG2 is measured. Determine whether INSIG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88236
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AASDHPPT is perturbed and the expression of TONSL is measured. Determine whether TONSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AASDHPPT is perturbed and the expression of TONSL is measured. Determine whether TONSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70346
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOP2 is perturbed and the expression of HCG18 is measured. Determine whether HCG18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NOP2 is perturbed and the expression of HCG18 is measured. Determine whether HCG18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43356
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPS6 and then measure expression of COX10. Does this perturbation cause a significant change in COX10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPS6 and then measure expression of COX10. Does this perturbation cause a significant change in COX10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27684
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SIRT7 is perturbed and DNAJB4 expression is observed. Does this perturbation lead to a significant difference in DNAJB4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SIRT7 is perturbed and DNAJB4 expression is observed. Does this perturbation lead to a significant difference in DNAJB4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22293
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UPF3A is perturbed and TMEM126B expression is measured. Determine whether TMEM126B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UPF3A is perturbed and TMEM126B expression is measured. Determine whether TMEM126B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13259
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TINF2, does the expression profile of LMLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TINF2, does the expression profile of LMLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105467
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3H and then measure expression of RPSA. Does this perturbation cause a significant change in RPSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3H and then measure expression of RPSA. Does this perturbation cause a significant change in RPSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91484
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEH1L is perturbed and the expression of VGLL3 is measured. Determine whether VGLL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEH1L is perturbed and the expression of VGLL3 is measured. Determine whether VGLL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68886
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR3B, does the expression profile of TRIB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR3B, does the expression profile of TRIB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55437
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1 is perturbed and the expression of SNAPC1 is measured. Does this perturbation cause a significant change in SNAPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1 is perturbed and the expression of SNAPC1 is measured. Does this perturbation cause a significant change in SNAPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101610
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb YTHDC1 and monitor C1orf56 expression. Decide whether this perturbation leads to a significant alteration in C1orf56 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YTHDC1 and monitor C1orf56 expression. Decide whether this perturbation leads to a significant alteration in C1orf56 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32648
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SON is perturbed and the expression of MOB2 is measured. Does this perturbation cause a significant change in MOB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SON is perturbed and the expression of MOB2 is measured. Does this perturbation cause a significant change in MOB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29060
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOC3L, does the expression profile of DPCD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOC3L, does the expression profile of DPCD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103687
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SP1 is perturbed and PTPRK expression is quantified. Does this perturbation result in a significant change in PTPRK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SP1 is perturbed and PTPRK expression is quantified. Does this perturbation result in a significant change in PTPRK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36362
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MBIP and monitor LAYN expression. Decide whether this perturbation leads to a significant alteration in LAYN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MBIP and monitor LAYN expression. Decide whether this perturbation leads to a significant alteration in LAYN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83548
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RMI1 is perturbed and DNASE1L1 expression is observed. Does this perturbation lead to a significant difference in DNASE1L1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RMI1 is perturbed and DNASE1L1 expression is observed. Does this perturbation lead to a significant difference in DNASE1L1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85553
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDCD2 is perturbed and the expression of LIMA1 is measured. Does this perturbation cause a significant change in LIMA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDCD2 is perturbed and the expression of LIMA1 is measured. Does this perturbation cause a significant change in LIMA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33710
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBCB is perturbed and the expression of MRS2 is measured. Determine whether MRS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBCB is perturbed and the expression of MRS2 is measured. Determine whether MRS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105336
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, INTS14 is perturbed and the expression of KRT80 is measured. Does this perturbation cause a significant change in KRT80 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, INTS14 is perturbed and the expression of KRT80 is measured. Does this perturbation cause a significant change in KRT80 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34580
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSR1 is perturbed and PBX1 expression is measured. Determine whether PBX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSR1 is perturbed and PBX1 expression is measured. Determine whether PBX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7109
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MED24 is perturbed and ZNF106 expression is observed. Does this perturbation lead to a significant difference in ZNF106 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MED24 is perturbed and ZNF106 expression is observed. Does this perturbation lead to a significant difference in ZNF106 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8483
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISCU is perturbed and KRCC1 expression is quantified. Does this perturbation result in a significant change in KRCC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISCU is perturbed and KRCC1 expression is quantified. Does this perturbation result in a significant change in KRCC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66002
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPS4 and examine the expression of RNF169. Does perturbing COPS4 lead to a significant change in RNF169 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPS4 and examine the expression of RNF169. Does perturbing COPS4 lead to a significant change in RNF169 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119741
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS29 and then measure expression of SLC35B3. Does this perturbation cause a significant change in SLC35B3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS29 and then measure expression of SLC35B3. Does this perturbation cause a significant change in SLC35B3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67404
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USF2 and then measure expression of NPEPPS. Does this perturbation cause a significant change in NPEPPS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USF2 and then measure expression of NPEPPS. Does this perturbation cause a significant change in NPEPPS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105394
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRRAP, does the expression profile of LTBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRRAP, does the expression profile of LTBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109917
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYF2 is perturbed and the expression of APAF1 is measured. Determine whether APAF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYF2 is perturbed and the expression of APAF1 is measured. Determine whether APAF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24476
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR1A, does the expression profile of IFT80 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR1A, does the expression profile of IFT80 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114257
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CIAO1 is perturbed and SDHA expression is observed. Does this perturbation lead to a significant difference in SDHA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CIAO1 is perturbed and SDHA expression is observed. Does this perturbation lead to a significant difference in SDHA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9703
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUVBL2 is associated with a significant change in GFM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUVBL2 is associated with a significant change in GFM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1605
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC45 and then measure expression of CHIC2. Does this perturbation cause a significant change in CHIC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC45 and then measure expression of CHIC2. Does this perturbation cause a significant change in CHIC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117614
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NCKAP1 and monitor B4GAT1 expression. Decide whether this perturbation leads to a significant alteration in B4GAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NCKAP1 and monitor B4GAT1 expression. Decide whether this perturbation leads to a significant alteration in B4GAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32918
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R2 is perturbed and the expression of VRK3 is measured. Does this perturbation cause a significant change in VRK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R2 is perturbed and the expression of VRK3 is measured. Does this perturbation cause a significant change in VRK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2000
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LSM4, does the expression profile of VGLL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LSM4, does the expression profile of VGLL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30747
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POLR3H and monitor NREP expression. Decide whether this perturbation leads to a significant alteration in NREP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POLR3H and monitor NREP expression. Decide whether this perturbation leads to a significant alteration in NREP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54588
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JAZF1 is perturbed and the expression of TMEM184B is measured. Determine whether TMEM184B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JAZF1 is perturbed and the expression of TMEM184B is measured. Determine whether TMEM184B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43526
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FAM136A is perturbed and the expression of FAM171B is measured. Determine whether FAM171B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FAM136A is perturbed and the expression of FAM171B is measured. Determine whether FAM171B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6266
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NF1 is perturbed and NUP188 expression is measured. Determine whether NUP188 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NF1 is perturbed and NUP188 expression is measured. Determine whether NUP188 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97469
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NDUFA3 and monitor CTSB expression. Decide whether this perturbation leads to a significant alteration in CTSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NDUFA3 and monitor CTSB expression. Decide whether this perturbation leads to a significant alteration in CTSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36488
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SMG1 and monitor ANAPC16 expression. Decide whether this perturbation leads to a significant alteration in ANAPC16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SMG1 and monitor ANAPC16 expression. Decide whether this perturbation leads to a significant alteration in ANAPC16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32028
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED10 and examine the expression of COL4A1. Does perturbing MED10 lead to a significant change in COL4A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED10 and examine the expression of COL4A1. Does perturbing MED10 lead to a significant change in COL4A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121081
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD5 is perturbed and the expression of SLC6A15 is measured. Does this perturbation cause a significant change in SLC6A15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SETD5 is perturbed and the expression of SLC6A15 is measured. Does this perturbation cause a significant change in SLC6A15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":340
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VCP, does the expression profile of HSF2BP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of VCP, does the expression profile of HSF2BP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90707
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNMT1 is associated with a significant change in THSD4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNMT1 is associated with a significant change in THSD4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100635
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOSC1 is associated with a significant change in LINC02762 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOSC1 is associated with a significant change in LINC02762 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95865
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2E2 and examine the expression of FBXO11. Does perturbing GTF2E2 lead to a significant change in FBXO11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2E2 and examine the expression of FBXO11. Does perturbing GTF2E2 lead to a significant change in FBXO11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15101
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHX36 is perturbed and the expression of CCDC82 is measured. Determine whether CCDC82 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHX36 is perturbed and the expression of CCDC82 is measured. Determine whether CCDC82 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71406
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIP7 and examine the expression of RPL41. Does perturbing NIP7 lead to a significant change in RPL41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIP7 and examine the expression of RPL41. Does perturbing NIP7 lead to a significant change in RPL41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93151
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHMP7 is perturbed and ORAI3 expression is measured. Determine whether ORAI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHMP7 is perturbed and ORAI3 expression is measured. Determine whether ORAI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101819
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL38 and then measure expression of GTF2F1. Does this perturbation cause a significant change in GTF2F1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL38 and then measure expression of GTF2F1. Does this perturbation cause a significant change in GTF2F1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41604
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3M is associated with a significant change in PCIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3M is associated with a significant change in PCIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39995
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBBP8, does the expression profile of RPS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBBP8, does the expression profile of RPS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69987
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ECT2 is perturbed and MFSD3 expression is quantified. Does this perturbation result in a significant change in MFSD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ECT2 is perturbed and MFSD3 expression is quantified. Does this perturbation result in a significant change in MFSD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49492
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF143 and monitor GIHCG expression. Decide whether this perturbation leads to a significant alteration in GIHCG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF143 and monitor GIHCG expression. Decide whether this perturbation leads to a significant alteration in GIHCG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42318
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ADSL and then measure expression of CHST12. Does this perturbation cause a significant change in CHST12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ADSL and then measure expression of CHST12. Does this perturbation cause a significant change in CHST12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32294
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBA3 is perturbed and STX1A expression is quantified. Does this perturbation result in a significant change in STX1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBA3 is perturbed and STX1A expression is quantified. Does this perturbation result in a significant change in STX1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39872
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC4 and examine the expression of CD44. Does perturbing ANAPC4 lead to a significant change in CD44 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC4 and examine the expression of CD44. Does perturbing ANAPC4 lead to a significant change in CD44 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29381
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SKA1 is perturbed and DHX40 expression is observed. Does this perturbation lead to a significant difference in DHX40 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SKA1 is perturbed and DHX40 expression is observed. Does this perturbation lead to a significant difference in DHX40 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66283
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HCFC1 is perturbed and STXBP1 expression is measured. Determine whether STXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HCFC1 is perturbed and STXBP1 expression is measured. Determine whether STXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96809
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPS6 is associated with a significant change in TNPO2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPS6 is associated with a significant change in TNPO2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27695
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and GCDH expression is quantified. Does this perturbation result in a significant change in GCDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and GCDH expression is quantified. Does this perturbation result in a significant change in GCDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94592
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARGLU1 and monitor ING5 expression. Decide whether this perturbation leads to a significant alteration in ING5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARGLU1 and monitor ING5 expression. Decide whether this perturbation leads to a significant alteration in ING5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76578
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ADSL is associated with a significant change in ECHS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ADSL is associated with a significant change in ECHS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32325
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3J, does the expression profile of PNRC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3J, does the expression profile of PNRC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12217
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTR2 is perturbed and the expression of USP45 is measured. Determine whether USP45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACTR2 is perturbed and the expression of USP45 is measured. Determine whether USP45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66986
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in EXOSC7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in EXOSC7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109695
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PHAX and examine the expression of UBE2E1. Does perturbing PHAX lead to a significant change in UBE2E1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PHAX and examine the expression of UBE2E1. Does perturbing PHAX lead to a significant change in UBE2E1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20561
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC1 is perturbed and NID2 expression is measured. Determine whether NID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC1 is perturbed and NID2 expression is measured. Determine whether NID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99969
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS17 is associated with a significant change in ZMYM5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS17 is associated with a significant change in ZMYM5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17125
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNOT11 is associated with a significant change in WDR74 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNOT11 is associated with a significant change in WDR74 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75415
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPTF is perturbed and COQ4 expression is quantified. Does this perturbation result in a significant change in COQ4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPTF is perturbed and COQ4 expression is quantified. Does this perturbation result in a significant change in COQ4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74132
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3A2 is associated with a significant change in MAGI1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3A2 is associated with a significant change in MAGI1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8135
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KXD1 is perturbed and the expression of SLC35E3 is measured. Does this perturbation cause a significant change in SLC35E3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KXD1 is perturbed and the expression of SLC35E3 is measured. Does this perturbation cause a significant change in SLC35E3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113860
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAPA and examine the expression of GPKOW. Does perturbing NAPA lead to a significant change in GPKOW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAPA and examine the expression of GPKOW. Does perturbing NAPA lead to a significant change in GPKOW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95981
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRPF8 and then measure expression of NEK7. Does this perturbation cause a significant change in NEK7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRPF8 and then measure expression of NEK7. Does this perturbation cause a significant change in NEK7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68204
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL13 is associated with a significant change in MMP24OS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL13 is associated with a significant change in MMP24OS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66725
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCNK and monitor SAYSD1 expression. Decide whether this perturbation leads to a significant alteration in SAYSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCNK and monitor SAYSD1 expression. Decide whether this perturbation leads to a significant alteration in SAYSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19608
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRCC2 and examine the expression of IRAK4. Does perturbing XRCC2 lead to a significant change in IRAK4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRCC2 and examine the expression of IRAK4. Does perturbing XRCC2 lead to a significant change in IRAK4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74561
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DMAP1 and then measure expression of TCP11L1. Does this perturbation cause a significant change in TCP11L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DMAP1 and then measure expression of TCP11L1. Does this perturbation cause a significant change in TCP11L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116734
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHQ1 and then measure expression of COL4A5. Does this perturbation cause a significant change in COL4A5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SHQ1 and then measure expression of COL4A5. Does this perturbation cause a significant change in COL4A5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76074
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LARS2 is perturbed and the expression of MFAP2 is measured. Does this perturbation cause a significant change in MFAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LARS2 is perturbed and the expression of MFAP2 is measured. Does this perturbation cause a significant change in MFAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64380
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GSK3B and examine the expression of MAGI3. Does perturbing GSK3B lead to a significant change in MAGI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GSK3B and examine the expression of MAGI3. Does perturbing GSK3B lead to a significant change in MAGI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38491
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PARN is perturbed and MDM2 expression is measured. Determine whether MDM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PARN is perturbed and MDM2 expression is measured. Determine whether MDM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37289
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VBP1 is perturbed and C5orf46 expression is quantified. Does this perturbation result in a significant change in C5orf46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VBP1 is perturbed and C5orf46 expression is quantified. Does this perturbation result in a significant change in C5orf46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75472
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPT16H and then measure expression of TMEM161B-AS1. Does this perturbation cause a significant change in TMEM161B-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPT16H and then measure expression of TMEM161B-AS1. Does this perturbation cause a significant change in TMEM161B-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114534
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRAPPC5 is perturbed and the expression of COQ5 is measured. Determine whether COQ5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TRAPPC5 is perturbed and the expression of COQ5 is measured. Determine whether COQ5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91126
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPP21, does the expression profile of NIBAN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPP21, does the expression profile of NIBAN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55537
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCS1L is perturbed and RYBP expression is quantified. Does this perturbation result in a significant change in RYBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCS1L is perturbed and RYBP expression is quantified. Does this perturbation result in a significant change in RYBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67502
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPLP0 is perturbed and the expression of NR3C1 is measured. Does this perturbation cause a significant change in NR3C1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPLP0 is perturbed and the expression of NR3C1 is measured. Does this perturbation cause a significant change in NR3C1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12350
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DBF4 and monitor GPC1 expression. Decide whether this perturbation leads to a significant alteration in GPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DBF4 and monitor GPC1 expression. Decide whether this perturbation leads to a significant alteration in GPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61868
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRMT10C is perturbed and the expression of RBM28 is measured. Does this perturbation cause a significant change in RBM28 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRMT10C is perturbed and the expression of RBM28 is measured. Does this perturbation cause a significant change in RBM28 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42380
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL6 is perturbed and the expression of BRPF1 is measured. Determine whether BRPF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL6 is perturbed and the expression of BRPF1 is measured. Determine whether BRPF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58646
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD2 and then measure expression of TFDP2. Does this perturbation cause a significant change in TFDP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD2 and then measure expression of TFDP2. Does this perturbation cause a significant change in TFDP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122354
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, THUMPD1 is perturbed and the expression of SMIM10L1 is measured. Does this perturbation cause a significant change in SMIM10L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, THUMPD1 is perturbed and the expression of SMIM10L1 is measured. Does this perturbation cause a significant change in SMIM10L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121900
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC9 is perturbed and SHB expression is quantified. Does this perturbation result in a significant change in SHB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC9 is perturbed and SHB expression is quantified. Does this perturbation result in a significant change in SHB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58262
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COX15 and examine the expression of MFSD1. Does perturbing COX15 lead to a significant change in MFSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COX15 and examine the expression of MFSD1. Does perturbing COX15 lead to a significant change in MFSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112891
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TRA2B and monitor DAPK1 expression. Decide whether this perturbation leads to a significant alteration in DAPK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TRA2B and monitor DAPK1 expression. Decide whether this perturbation leads to a significant alteration in DAPK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50378
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISY1 is perturbed and DNAJC24 expression is measured. Determine whether DNAJC24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISY1 is perturbed and DNAJC24 expression is measured. Determine whether DNAJC24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103999
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DPM2 and examine the expression of CLN3. Does perturbing DPM2 lead to a significant change in CLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DPM2 and examine the expression of CLN3. Does perturbing DPM2 lead to a significant change in CLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26401
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3A and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GTF3A and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111994
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL46 is associated with a significant change in RPUSD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL46 is associated with a significant change in RPUSD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3495
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3L, does the expression profile of CENPL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3L, does the expression profile of CENPL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9417
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL12 is perturbed and SNHG17 expression is observed. Does this perturbation lead to a significant difference in SNHG17 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL12 is perturbed and SNHG17 expression is observed. Does this perturbation lead to a significant difference in SNHG17 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25953
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1D and examine the expression of TGFB1. Does perturbing ATP6V1D lead to a significant change in TGFB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1D and examine the expression of TGFB1. Does perturbing ATP6V1D lead to a significant change in TGFB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12651
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO13 is perturbed and YDJC expression is quantified. Does this perturbation result in a significant change in YDJC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO13 is perturbed and YDJC expression is quantified. Does this perturbation result in a significant change in YDJC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7872
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OGT and monitor MYL12B expression. Decide whether this perturbation leads to a significant alteration in MYL12B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OGT and monitor MYL12B expression. Decide whether this perturbation leads to a significant alteration in MYL12B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112308
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PHB2 and then measure expression of SPP1. Does this perturbation cause a significant change in SPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PHB2 and then measure expression of SPP1. Does this perturbation cause a significant change in SPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63914
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YPEL5 is perturbed and the expression of DMTF1 is measured. Does this perturbation cause a significant change in DMTF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YPEL5 is perturbed and the expression of DMTF1 is measured. Does this perturbation cause a significant change in DMTF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44340
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL10A and examine the expression of SH3BGRL. Does perturbing RPL10A lead to a significant change in SH3BGRL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL10A and examine the expression of SH3BGRL. Does perturbing RPL10A lead to a significant change in SH3BGRL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87431
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNX15 is perturbed and the expression of SLC25A38 is measured. Determine whether SLC25A38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNX15 is perturbed and the expression of SLC25A38 is measured. Determine whether SLC25A38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15876
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EEFSEC, does the expression profile of H2AFJ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EEFSEC, does the expression profile of H2AFJ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86707
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDCD3 and examine the expression of GPC1. Does perturbing NUDCD3 lead to a significant change in GPC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUDCD3 and examine the expression of GPC1. Does perturbing NUDCD3 lead to a significant change in GPC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9801
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG1 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG1 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81612
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCAF6 is perturbed and the expression of PEPD is measured. Determine whether PEPD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCAF6 is perturbed and the expression of PEPD is measured. Determine whether PEPD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6546
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL39 and then measure expression of STK38L. Does this perturbation cause a significant change in STK38L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL39 and then measure expression of STK38L. Does this perturbation cause a significant change in STK38L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37114
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PGAM5 is perturbed and the expression of TRIM27 is measured. Determine whether TRIM27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PGAM5 is perturbed and the expression of TRIM27 is measured. Determine whether TRIM27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1246
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED7 is associated with a significant change in H2AFY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED7 is associated with a significant change in H2AFY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106545
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD1 is perturbed and LINC00467 expression is observed. Does this perturbation lead to a significant difference in LINC00467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD1 is perturbed and LINC00467 expression is observed. Does this perturbation lead to a significant difference in LINC00467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25623
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDC42 is perturbed and DNAJC4 expression is observed. Does this perturbation lead to a significant difference in DNAJC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDC42 is perturbed and DNAJC4 expression is observed. Does this perturbation lead to a significant difference in DNAJC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86643
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor CENPV expression. Decide whether this perturbation leads to a significant alteration in CENPV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor CENPV expression. Decide whether this perturbation leads to a significant alteration in CENPV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88388
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and MOCS2 expression is quantified. Does this perturbation result in a significant change in MOCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and MOCS2 expression is quantified. Does this perturbation result in a significant change in MOCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99402
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EWSR1 is perturbed and ZNF766 expression is observed. Does this perturbation lead to a significant difference in ZNF766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EWSR1 is perturbed and ZNF766 expression is observed. Does this perturbation lead to a significant difference in ZNF766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54383
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC1 and examine the expression of SMYD4. Does perturbing TRAPPC1 lead to a significant change in SMYD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC1 and examine the expression of SMYD4. Does perturbing TRAPPC1 lead to a significant change in SMYD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56461
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KAT5 and examine the expression of PTEN. Does perturbing KAT5 lead to a significant change in PTEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KAT5 and examine the expression of PTEN. Does perturbing KAT5 lead to a significant change in PTEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84061
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GEMIN4 is perturbed and the expression of CYBRD1 is measured. Determine whether CYBRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GEMIN4 is perturbed and the expression of CYBRD1 is measured. Determine whether CYBRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1916
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1 is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1 is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101582
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDX5 and then measure expression of SP140L. Does this perturbation cause a significant change in SP140L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDX5 and then measure expression of SP140L. Does this perturbation cause a significant change in SP140L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17434
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TCOF1 is perturbed and IL1B expression is measured. Determine whether IL1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TCOF1 is perturbed and IL1B expression is measured. Determine whether IL1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83929
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSGEP is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSGEP is perturbed and the expression of NUPR1 is measured. Determine whether NUPR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51216
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor UTP25 expression. Decide whether this perturbation leads to a significant alteration in UTP25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor UTP25 expression. Decide whether this perturbation leads to a significant alteration in UTP25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42078
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb WDR61 and monitor MEST expression. Decide whether this perturbation leads to a significant alteration in MEST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb WDR61 and monitor MEST expression. Decide whether this perturbation leads to a significant alteration in MEST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86348
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL18 is perturbed and the expression of ZC3H12C is measured. Determine whether ZC3H12C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL18 is perturbed and the expression of ZC3H12C is measured. Determine whether ZC3H12C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82946
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PABPC1 is perturbed and VEGFA expression is measured. Determine whether VEGFA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PABPC1 is perturbed and VEGFA expression is measured. Determine whether VEGFA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70559
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NUP160 is perturbed and CREBL2 expression is measured. Determine whether CREBL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NUP160 is perturbed and CREBL2 expression is measured. Determine whether CREBL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16859
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of PPIB. Does perturbing DHDDS lead to a significant change in PPIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of PPIB. Does perturbing DHDDS lead to a significant change in PPIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32411
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KRT8 is perturbed and OSBPL6 expression is quantified. Does this perturbation result in a significant change in OSBPL6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KRT8 is perturbed and OSBPL6 expression is quantified. Does this perturbation result in a significant change in OSBPL6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25082
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDCD7 and then measure expression of GALNT4. Does this perturbation cause a significant change in GALNT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDCD7 and then measure expression of GALNT4. Does this perturbation cause a significant change in GALNT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74914
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEPCE is perturbed and TGIF1 expression is quantified. Does this perturbation result in a significant change in TGIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEPCE is perturbed and TGIF1 expression is quantified. Does this perturbation result in a significant change in TGIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109332
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RBM12 and monitor SCN9A expression. Decide whether this perturbation leads to a significant alteration in SCN9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RBM12 and monitor SCN9A expression. Decide whether this perturbation leads to a significant alteration in SCN9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21258
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL38 is perturbed and the expression of YIPF5 is measured. Does this perturbation cause a significant change in YIPF5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL38 is perturbed and the expression of YIPF5 is measured. Does this perturbation cause a significant change in YIPF5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41570
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS23 is perturbed and CPOX expression is quantified. Does this perturbation result in a significant change in CPOX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS23 is perturbed and CPOX expression is quantified. Does this perturbation result in a significant change in CPOX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23472
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DPH3 is perturbed and MTMR9 expression is observed. Does this perturbation lead to a significant difference in MTMR9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DPH3 is perturbed and MTMR9 expression is observed. Does this perturbation lead to a significant difference in MTMR9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46743
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS25 and then measure expression of PATL1. Does this perturbation cause a significant change in PATL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS25 and then measure expression of PATL1. Does this perturbation cause a significant change in PATL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8634
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SKP1 and examine the expression of IER3IP1. Does perturbing SKP1 lead to a significant change in IER3IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SKP1 and examine the expression of IER3IP1. Does perturbing SKP1 lead to a significant change in IER3IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107791
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX37 and then measure expression of NUDT4. Does this perturbation cause a significant change in NUDT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX37 and then measure expression of NUDT4. Does this perturbation cause a significant change in NUDT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91864
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHMP2A, does the expression profile of TMEM132A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHMP2A, does the expression profile of TMEM132A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121567
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP160 and examine the expression of KIDINS220. Does perturbing NUP160 lead to a significant change in KIDINS220 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP160 and examine the expression of KIDINS220. Does perturbing NUP160 lead to a significant change in KIDINS220 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16841
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAPC3 is perturbed and the expression of SUPV3L1 is measured. Determine whether SUPV3L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAPC3 is perturbed and the expression of SUPV3L1 is measured. Determine whether SUPV3L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54996
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C1 is perturbed and YIPF4 expression is observed. Does this perturbation lead to a significant difference in YIPF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C1 is perturbed and YIPF4 expression is observed. Does this perturbation lead to a significant difference in YIPF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13343
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C3 is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GTF3C3 is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73253
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGLN2 and examine the expression of REEP4. Does perturbing EGLN2 lead to a significant change in REEP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGLN2 and examine the expression of REEP4. Does perturbing EGLN2 lead to a significant change in REEP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20621
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3H and examine the expression of SSX2IP. Does perturbing EIF3H lead to a significant change in SSX2IP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3H and examine the expression of SSX2IP. Does perturbing EIF3H lead to a significant change in SSX2IP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91461
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RCOR1 and examine the expression of MAFF. Does perturbing RCOR1 lead to a significant change in MAFF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RCOR1 and examine the expression of MAFF. Does perturbing RCOR1 lead to a significant change in MAFF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36221
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRSF3 and monitor GLRB expression. Decide whether this perturbation leads to a significant alteration in GLRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRSF3 and monitor GLRB expression. Decide whether this perturbation leads to a significant alteration in GLRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63528
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNRNPU is perturbed and the expression of HIBCH is measured. Does this perturbation cause a significant change in HIBCH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNRNPU is perturbed and the expression of HIBCH is measured. Does this perturbation cause a significant change in HIBCH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105060
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PMPCA is perturbed and UPP1 expression is measured. Determine whether UPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PMPCA is perturbed and UPP1 expression is measured. Determine whether UPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72009
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDTC1 is perturbed and the expression of ATXN7L3B is measured. Determine whether ATXN7L3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDTC1 is perturbed and the expression of ATXN7L3B is measured. Determine whether ATXN7L3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3136
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RABGGTA and then measure expression of DENND5A. Does this perturbation cause a significant change in DENND5A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RABGGTA and then measure expression of DENND5A. Does this perturbation cause a significant change in DENND5A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61134
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NPM1 is associated with a significant change in TNFRSF10D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NPM1 is associated with a significant change in TNFRSF10D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59635
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC7A5 is associated with a significant change in PA2G4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC7A5 is associated with a significant change in PA2G4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28905
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF4, does the expression profile of VCPIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF4, does the expression profile of VCPIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111927
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDT1 and then measure expression of TNIK. Does this perturbation cause a significant change in TNIK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDT1 and then measure expression of TNIK. Does this perturbation cause a significant change in TNIK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21104
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP2R3C is perturbed and the expression of RBM6 is measured. Determine whether RBM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP2R3C is perturbed and the expression of RBM6 is measured. Determine whether RBM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43606
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb USP8 and monitor MRPS36 expression. Decide whether this perturbation leads to a significant alteration in MRPS36 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb USP8 and monitor MRPS36 expression. Decide whether this perturbation leads to a significant alteration in MRPS36 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5068
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HERC1 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HERC1 and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43664
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATR is perturbed and NDUFAF8 expression is measured. Determine whether NDUFAF8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATR is perturbed and NDUFAF8 expression is measured. Determine whether NDUFAF8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80449
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HEATR1 and monitor ZNF3 expression. Decide whether this perturbation leads to a significant alteration in ZNF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HEATR1 and monitor ZNF3 expression. Decide whether this perturbation leads to a significant alteration in ZNF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2178
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EEFSEC is perturbed and H2AFJ expression is measured. Determine whether H2AFJ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EEFSEC is perturbed and H2AFJ expression is measured. Determine whether H2AFJ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86709
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MALSU1 is associated with a significant change in NANS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MALSU1 is associated with a significant change in NANS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":865
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP2R3C is perturbed and KDELR3 expression is measured. Determine whether KDELR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP2R3C is perturbed and KDELR3 expression is measured. Determine whether KDELR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43619
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMC4 is perturbed and the expression of NPC1 is measured. Does this perturbation cause a significant change in NPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMC4 is perturbed and the expression of NPC1 is measured. Does this perturbation cause a significant change in NPC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71700
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF11 is associated with a significant change in ANAPC13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF11 is associated with a significant change in ANAPC13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38225
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3I and then measure expression of NXT1. Does this perturbation cause a significant change in NXT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3I and then measure expression of NXT1. Does this perturbation cause a significant change in NXT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66424
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UTP18, does the expression profile of CYLD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UTP18, does the expression profile of CYLD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111607
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACIN1 is perturbed and the expression of EEF1AKNMT is measured. Determine whether EEF1AKNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ACIN1 is perturbed and the expression of EEF1AKNMT is measured. Determine whether EEF1AKNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20766
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCTN1 is perturbed and ACTR6 expression is quantified. Does this perturbation result in a significant change in ACTR6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCTN1 is perturbed and ACTR6 expression is quantified. Does this perturbation result in a significant change in ACTR6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21942
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HIRA is perturbed and PNISR expression is quantified. Does this perturbation result in a significant change in PNISR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HIRA is perturbed and PNISR expression is quantified. Does this perturbation result in a significant change in PNISR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50362
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AP2A1, does the expression profile of GALNT10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AP2A1, does the expression profile of GALNT10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96017
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC40, does the expression profile of SGSM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC40, does the expression profile of SGSM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94777
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD13 is associated with a significant change in TTLL7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD13 is associated with a significant change in TTLL7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79195
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5ME is perturbed and IPO4 expression is observed. Does this perturbation lead to a significant difference in IPO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5ME is perturbed and IPO4 expression is observed. Does this perturbation lead to a significant difference in IPO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86103
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3B5 is associated with a significant change in NADSYN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SF3B5 is associated with a significant change in NADSYN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16075
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LTBP3 and monitor CRIP2 expression. Decide whether this perturbation leads to a significant alteration in CRIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LTBP3 and monitor CRIP2 expression. Decide whether this perturbation leads to a significant alteration in CRIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42948
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPAP2 is perturbed and PHF3 expression is quantified. Does this perturbation result in a significant change in PHF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPAP2 is perturbed and PHF3 expression is quantified. Does this perturbation result in a significant change in PHF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24232
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UQCRB, does the expression profile of KRIT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UQCRB, does the expression profile of KRIT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68127
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX19B is associated with a significant change in SUSD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX19B is associated with a significant change in SUSD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54235
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RNF103 is perturbed and PAF1 expression is quantified. Does this perturbation result in a significant change in PAF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RNF103 is perturbed and PAF1 expression is quantified. Does this perturbation result in a significant change in PAF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11882
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RABGGTB is perturbed and the expression of CMPK1 is measured. Does this perturbation cause a significant change in CMPK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RABGGTB is perturbed and the expression of CMPK1 is measured. Does this perturbation cause a significant change in CMPK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47080
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL42 is perturbed and MLXIP expression is measured. Determine whether MLXIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL42 is perturbed and MLXIP expression is measured. Determine whether MLXIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91519
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF3 is perturbed and the expression of PEBP1 is measured. Does this perturbation cause a significant change in PEBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF3 is perturbed and the expression of PEBP1 is measured. Does this perturbation cause a significant change in PEBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7980
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBA2 and then measure expression of KLHL21. Does this perturbation cause a significant change in KLHL21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBA2 and then measure expression of KLHL21. Does this perturbation cause a significant change in KLHL21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68954
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRRC2A, does the expression profile of COX11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRRC2A, does the expression profile of COX11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9797
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL32 is perturbed and the expression of TMEM19 is measured. Determine whether TMEM19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL32 is perturbed and the expression of TMEM19 is measured. Determine whether TMEM19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17316
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KPNA6 is perturbed and RTL8C expression is quantified. Does this perturbation result in a significant change in RTL8C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KPNA6 is perturbed and RTL8C expression is quantified. Does this perturbation result in a significant change in RTL8C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12492
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM4 and examine the expression of VGLL4. Does perturbing LSM4 lead to a significant change in VGLL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM4 and examine the expression of VGLL4. Does perturbing LSM4 lead to a significant change in VGLL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30741
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VARS is perturbed and GAS5 expression is measured. Determine whether GAS5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VARS is perturbed and GAS5 expression is measured. Determine whether GAS5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10369
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAD2L2 is perturbed and MED28 expression is observed. Does this perturbation lead to a significant difference in MED28 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAD2L2 is perturbed and MED28 expression is observed. Does this perturbation lead to a significant difference in MED28 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31013
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCDC6 is perturbed and COPS3 expression is observed. Does this perturbation lead to a significant difference in COPS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCDC6 is perturbed and COPS3 expression is observed. Does this perturbation lead to a significant difference in COPS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1503
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF6 and then measure expression of TMEM99. Does this perturbation cause a significant change in TMEM99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF6 and then measure expression of TMEM99. Does this perturbation cause a significant change in TMEM99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29234
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BDP1 and examine the expression of TAOK1. Does perturbing BDP1 lead to a significant change in TAOK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BDP1 and examine the expression of TAOK1. Does perturbing BDP1 lead to a significant change in TAOK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49391
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FAM32A is perturbed and PTPN2 expression is measured. Determine whether PTPN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FAM32A is perturbed and PTPN2 expression is measured. Determine whether PTPN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114399
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FIP1L1 and then measure expression of SUMF1. Does this perturbation cause a significant change in SUMF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FIP1L1 and then measure expression of SUMF1. Does this perturbation cause a significant change in SUMF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121514
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELL is perturbed and the expression of CRYZ is measured. Determine whether CRYZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELL is perturbed and the expression of CRYZ is measured. Determine whether CRYZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31566
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX21 is perturbed and ACAP2 expression is quantified. Does this perturbation result in a significant change in ACAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX21 is perturbed and ACAP2 expression is quantified. Does this perturbation result in a significant change in ACAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113912
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ADSL is associated with a significant change in FANCD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ADSL is associated with a significant change in FANCD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32335
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4E is associated with a significant change in PLGRKT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF4E is associated with a significant change in PLGRKT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7415
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HAUS6 is perturbed and SNAPC1 expression is measured. Determine whether SNAPC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HAUS6 is perturbed and SNAPC1 expression is measured. Determine whether SNAPC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64509
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HEATR1 and monitor ACTA2 expression. Decide whether this perturbation leads to a significant alteration in ACTA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HEATR1 and monitor ACTA2 expression. Decide whether this perturbation leads to a significant alteration in ACTA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2148
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDE2 is perturbed and ZMAT2 expression is observed. Does this perturbation lead to a significant difference in ZMAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDE2 is perturbed and ZMAT2 expression is observed. Does this perturbation lead to a significant difference in ZMAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115903
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NHP2 is perturbed and HIPK2 expression is observed. Does this perturbation lead to a significant difference in HIPK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NHP2 is perturbed and HIPK2 expression is observed. Does this perturbation lead to a significant difference in HIPK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96443
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EDC4 and then measure expression of JUP. Does this perturbation cause a significant change in JUP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EDC4 and then measure expression of JUP. Does this perturbation cause a significant change in JUP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44704
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COX15 is associated with a significant change in SPSB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COX15 is associated with a significant change in SPSB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112905
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGS1 and examine the expression of TTLL5. Does perturbing PGS1 lead to a significant change in TTLL5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGS1 and examine the expression of TTLL5. Does perturbing PGS1 lead to a significant change in TTLL5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3581
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3H13 is perturbed and NRP2 expression is measured. Determine whether NRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3H13 is perturbed and NRP2 expression is measured. Determine whether NRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2569
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRXL2A is perturbed and SLC39A1 expression is observed. Does this perturbation lead to a significant difference in SLC39A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRXL2A is perturbed and SLC39A1 expression is observed. Does this perturbation lead to a significant difference in SLC39A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32823
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PEX1 is perturbed and YBEY expression is quantified. Does this perturbation result in a significant change in YBEY expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PEX1 is perturbed and YBEY expression is quantified. Does this perturbation result in a significant change in YBEY expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121802
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL4 and then measure expression of TMEM99. Does this perturbation cause a significant change in TMEM99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL4 and then measure expression of TMEM99. Does this perturbation cause a significant change in TMEM99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56984
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TEX10, does the expression profile of WBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TEX10, does the expression profile of WBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59287
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS29 is associated with a significant change in POFUT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS29 is associated with a significant change in POFUT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87835
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GSPT1 is perturbed and the expression of B4GALT5 is measured. Determine whether B4GALT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GSPT1 is perturbed and the expression of B4GALT5 is measured. Determine whether B4GALT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102746
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRMT5 is perturbed and RGS12 expression is quantified. Does this perturbation result in a significant change in RGS12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRMT5 is perturbed and RGS12 expression is quantified. Does this perturbation result in a significant change in RGS12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39902
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC3 and examine the expression of PLK2. Does perturbing THOC3 lead to a significant change in PLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC3 and examine the expression of PLK2. Does perturbing THOC3 lead to a significant change in PLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11181
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPT6H, does the expression profile of SLC25A29 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPT6H, does the expression profile of SLC25A29 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105157
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TLN1 is perturbed and KIFAP3 expression is quantified. Does this perturbation result in a significant change in KIFAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TLN1 is perturbed and KIFAP3 expression is quantified. Does this perturbation result in a significant change in KIFAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94482
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEPCE and monitor ACADSB expression. Decide whether this perturbation leads to a significant alteration in ACADSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEPCE and monitor ACADSB expression. Decide whether this perturbation leads to a significant alteration in ACADSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109348
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CTDP1 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CTDP1 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31170
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RTCB is perturbed and the expression of RETREG1 is measured. Determine whether RETREG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RTCB is perturbed and the expression of RETREG1 is measured. Determine whether RETREG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18456
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPU and monitor DNAJB11 expression. Decide whether this perturbation leads to a significant alteration in DNAJB11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPU and monitor DNAJB11 expression. Decide whether this perturbation leads to a significant alteration in DNAJB11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105098
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ADSL and monitor ECHS1 expression. Decide whether this perturbation leads to a significant alteration in ECHS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ADSL and monitor ECHS1 expression. Decide whether this perturbation leads to a significant alteration in ECHS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32328
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNL3L is perturbed and the expression of TSPAN5 is measured. Does this perturbation cause a significant change in TSPAN5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNL3L is perturbed and the expression of TSPAN5 is measured. Does this perturbation cause a significant change in TSPAN5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114680
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MCM7 and monitor MXD4 expression. Decide whether this perturbation leads to a significant alteration in MXD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MCM7 and monitor MXD4 expression. Decide whether this perturbation leads to a significant alteration in MXD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109638
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DRAP1 is perturbed and the expression of RABGGTA is measured. Does this perturbation cause a significant change in RABGGTA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DRAP1 is perturbed and the expression of RABGGTA is measured. Does this perturbation cause a significant change in RABGGTA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87320
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of TGFBR2 is measured. Determine whether TGFBR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of TGFBR2 is measured. Determine whether TGFBR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118926
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PKMYT1 is associated with a significant change in PIP4K2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PKMYT1 is associated with a significant change in PIP4K2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57045
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUS1 and then measure expression of DDX20. Does this perturbation cause a significant change in DDX20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUS1 and then measure expression of DDX20. Does this perturbation cause a significant change in DDX20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83264
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NOL8 is perturbed and SLC35C1 expression is quantified. Does this perturbation result in a significant change in SLC35C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NOL8 is perturbed and SLC35C1 expression is quantified. Does this perturbation result in a significant change in SLC35C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34732
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ELP3 and monitor GPR176 expression. Decide whether this perturbation leads to a significant alteration in GPR176 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ELP3 and monitor GPR176 expression. Decide whether this perturbation leads to a significant alteration in GPR176 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44028
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUD31 and then measure expression of NFE2L1. Does this perturbation cause a significant change in NFE2L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUD31 and then measure expression of NFE2L1. Does this perturbation cause a significant change in NFE2L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36604
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMC5 is perturbed and NKTR expression is quantified. Does this perturbation result in a significant change in NKTR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMC5 is perturbed and NKTR expression is quantified. Does this perturbation result in a significant change in NKTR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108342
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and EOGT expression is observed. Does this perturbation lead to a significant difference in EOGT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and EOGT expression is observed. Does this perturbation lead to a significant difference in EOGT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49813
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX19A, does the expression profile of ENOSF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX19A, does the expression profile of ENOSF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24937
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PNN and examine the expression of SLC17A5. Does perturbing PNN lead to a significant change in SLC17A5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PNN and examine the expression of SLC17A5. Does perturbing PNN lead to a significant change in SLC17A5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62861
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CACNB3 is perturbed and CC2D1A expression is observed. Does this perturbation lead to a significant difference in CC2D1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CACNB3 is perturbed and CC2D1A expression is observed. Does this perturbation lead to a significant difference in CC2D1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33793
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBR5 and examine the expression of KIAA1522. Does perturbing UBR5 lead to a significant change in KIAA1522 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBR5 and examine the expression of KIAA1522. Does perturbing UBR5 lead to a significant change in KIAA1522 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21041
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UCHL5 is perturbed and the expression of ZKSCAN1 is measured. Determine whether ZKSCAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UCHL5 is perturbed and the expression of ZKSCAN1 is measured. Determine whether ZKSCAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25586
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSME2 is perturbed and the expression of ARID2 is measured. Does this perturbation cause a significant change in ARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSME2 is perturbed and the expression of ARID2 is measured. Does this perturbation cause a significant change in ARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66360
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GAR1 is perturbed and TMEM179B expression is measured. Determine whether TMEM179B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GAR1 is perturbed and TMEM179B expression is measured. Determine whether TMEM179B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11009
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS2 is perturbed and the expression of RNF121 is measured. Does this perturbation cause a significant change in RNF121 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPS2 is perturbed and the expression of RNF121 is measured. Does this perturbation cause a significant change in RNF121 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33380
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS17 is perturbed and the expression of WIPF2 is measured. Determine whether WIPF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS17 is perturbed and the expression of WIPF2 is measured. Determine whether WIPF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92396
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UPF2 and then measure expression of RALGAPA1. Does this perturbation cause a significant change in RALGAPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UPF2 and then measure expression of RALGAPA1. Does this perturbation cause a significant change in RALGAPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19214
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and UTP23 expression is measured. Determine whether UTP23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and UTP23 expression is measured. Determine whether UTP23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107729
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CFDP1 and examine the expression of BDNF. Does perturbing CFDP1 lead to a significant change in BDNF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CFDP1 and examine the expression of BDNF. Does perturbing CFDP1 lead to a significant change in BDNF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35731
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NF1 is perturbed and the expression of NUP188 is measured. Does this perturbation cause a significant change in NUP188 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NF1 is perturbed and the expression of NUP188 is measured. Does this perturbation cause a significant change in NUP188 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97460
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHTOP is perturbed and RAB4A expression is measured. Determine whether RAB4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHTOP is perturbed and RAB4A expression is measured. Determine whether RAB4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23089
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR83OS is perturbed and the expression of B4GAT1 is measured. Does this perturbation cause a significant change in B4GAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR83OS is perturbed and the expression of B4GAT1 is measured. Does this perturbation cause a significant change in B4GAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67990
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUP153 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUP153 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13304
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POT1 is perturbed and AK1 expression is quantified. Does this perturbation result in a significant change in AK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POT1 is perturbed and AK1 expression is quantified. Does this perturbation result in a significant change in AK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116632
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, METTL3 is perturbed and the expression of NISCH is measured. Determine whether NISCH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, METTL3 is perturbed and the expression of NISCH is measured. Determine whether NISCH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47046
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRPF38A is perturbed and DYNLL2 expression is measured. Determine whether DYNLL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRPF38A is perturbed and DYNLL2 expression is measured. Determine whether DYNLL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40079
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP43, does the expression profile of BDNF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP43, does the expression profile of BDNF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79567
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MED19 is perturbed and MKLN1 expression is observed. Does this perturbation lead to a significant difference in MKLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MED19 is perturbed and MKLN1 expression is observed. Does this perturbation lead to a significant difference in MKLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29553
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBM28 is perturbed and the expression of STX6 is measured. Does this perturbation cause a significant change in STX6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBM28 is perturbed and the expression of STX6 is measured. Does this perturbation cause a significant change in STX6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68400
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and NUCB2 expression is measured. Determine whether NUCB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and NUCB2 expression is measured. Determine whether NUCB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69789
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YAE1 and then measure expression of MGST2. Does this perturbation cause a significant change in MGST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YAE1 and then measure expression of MGST2. Does this perturbation cause a significant change in MGST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112674
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TFAM and examine the expression of RBM18. Does perturbing TFAM lead to a significant change in RBM18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TFAM and examine the expression of RBM18. Does perturbing TFAM lead to a significant change in RBM18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1271
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLEKHN1 is perturbed and GPC6 expression is quantified. Does this perturbation result in a significant change in GPC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLEKHN1 is perturbed and GPC6 expression is quantified. Does this perturbation result in a significant change in GPC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47732
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPM and monitor LATS1 expression. Decide whether this perturbation leads to a significant alteration in LATS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNRNPM and monitor LATS1 expression. Decide whether this perturbation leads to a significant alteration in LATS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60568
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF4A1 is perturbed and CPEB4 expression is observed. Does this perturbation lead to a significant difference in CPEB4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF4A1 is perturbed and CPEB4 expression is observed. Does this perturbation lead to a significant difference in CPEB4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111533
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPM is perturbed and NTPCR expression is measured. Determine whether NTPCR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPM is perturbed and NTPCR expression is measured. Determine whether NTPCR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60589
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPA1 is perturbed and ANXA3 expression is quantified. Does this perturbation result in a significant change in ANXA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPA1 is perturbed and ANXA3 expression is quantified. Does this perturbation result in a significant change in ANXA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4822
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC13 and examine the expression of DNAJC4. Does perturbing ANAPC13 lead to a significant change in DNAJC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANAPC13 and examine the expression of DNAJC4. Does perturbing ANAPC13 lead to a significant change in DNAJC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22751
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BARD1, does the expression profile of FBLIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BARD1, does the expression profile of FBLIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122827
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRTO4 is associated with a significant change in PMP22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRTO4 is associated with a significant change in PMP22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112105
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TCP1 is perturbed and the expression of ITGAV is measured. Does this perturbation cause a significant change in ITGAV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TCP1 is perturbed and the expression of ITGAV is measured. Does this perturbation cause a significant change in ITGAV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16300
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GABPB1 is perturbed and PRRC2B expression is observed. Does this perturbation lead to a significant difference in PRRC2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GABPB1 is perturbed and PRRC2B expression is observed. Does this perturbation lead to a significant difference in PRRC2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98133
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB10 is perturbed and PDLIM1 expression is measured. Determine whether PDLIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB10 is perturbed and PDLIM1 expression is measured. Determine whether PDLIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9479
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRNT1 is perturbed and FBXO25 expression is quantified. Does this perturbation result in a significant change in FBXO25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRNT1 is perturbed and FBXO25 expression is quantified. Does this perturbation result in a significant change in FBXO25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2012
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAPC1 and monitor TOR1AIP1 expression. Decide whether this perturbation leads to a significant alteration in TOR1AIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAPC1 and monitor TOR1AIP1 expression. Decide whether this perturbation leads to a significant alteration in TOR1AIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119968
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SSU72 and examine the expression of CCNDBP1. Does perturbing SSU72 lead to a significant change in CCNDBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SSU72 and examine the expression of CCNDBP1. Does perturbing SSU72 lead to a significant change in CCNDBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59831
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDCD5 is perturbed and MXD4 expression is quantified. Does this perturbation result in a significant change in MXD4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDCD5 is perturbed and MXD4 expression is quantified. Does this perturbation result in a significant change in MXD4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20842
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSCB and monitor PIP5K1C expression. Decide whether this perturbation leads to a significant alteration in PIP5K1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSCB and monitor PIP5K1C expression. Decide whether this perturbation leads to a significant alteration in PIP5K1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23438
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RIOK1 and monitor ELP1 expression. Decide whether this perturbation leads to a significant alteration in ELP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RIOK1 and monitor ELP1 expression. Decide whether this perturbation leads to a significant alteration in ELP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15868
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MCL1 is perturbed and the expression of IDH2 is measured. Determine whether IDH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MCL1 is perturbed and the expression of IDH2 is measured. Determine whether IDH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6776
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRMT5, does the expression profile of RBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TRMT5, does the expression profile of RBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10967
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MYBBP1A is perturbed and PRDX5 expression is quantified. Does this perturbation result in a significant change in PRDX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MYBBP1A is perturbed and PRDX5 expression is quantified. Does this perturbation result in a significant change in PRDX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4462
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TEAD3 and monitor TMEM101 expression. Decide whether this perturbation leads to a significant alteration in TMEM101 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TEAD3 and monitor TMEM101 expression. Decide whether this perturbation leads to a significant alteration in TMEM101 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35148
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HMGCR and monitor TMEM233 expression. Decide whether this perturbation leads to a significant alteration in TMEM233 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HMGCR and monitor TMEM233 expression. Decide whether this perturbation leads to a significant alteration in TMEM233 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90988
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBE3C is perturbed and the expression of COG6 is measured. Determine whether COG6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBE3C is perturbed and the expression of COG6 is measured. Determine whether COG6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83426
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL39 is perturbed and the expression of EIF1B is measured. Does this perturbation cause a significant change in EIF1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL39 is perturbed and the expression of EIF1B is measured. Does this perturbation cause a significant change in EIF1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37100
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ADNP2 and monitor TOPORS expression. Decide whether this perturbation leads to a significant alteration in TOPORS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ADNP2 and monitor TOPORS expression. Decide whether this perturbation leads to a significant alteration in TOPORS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114148
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRS1 is perturbed and the expression of UBE2L3 is measured. Determine whether UBE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RRS1 is perturbed and the expression of UBE2L3 is measured. Determine whether UBE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55686
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DBF4 is perturbed and LAPTM4B expression is observed. Does this perturbation lead to a significant difference in LAPTM4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DBF4 is perturbed and LAPTM4B expression is observed. Does this perturbation lead to a significant difference in LAPTM4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61903
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBL5 and then measure expression of BAZ2A. Does this perturbation cause a significant change in BAZ2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBL5 and then measure expression of BAZ2A. Does this perturbation cause a significant change in BAZ2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99714
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TOMM20 is perturbed and STAMBP expression is quantified. Does this perturbation result in a significant change in STAMBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TOMM20 is perturbed and STAMBP expression is quantified. Does this perturbation result in a significant change in STAMBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14952
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MMS19, does the expression profile of RBM42 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MMS19, does the expression profile of RBM42 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26377
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SETX is perturbed and ARFGAP2 expression is quantified. Does this perturbation result in a significant change in ARFGAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SETX is perturbed and ARFGAP2 expression is quantified. Does this perturbation result in a significant change in ARFGAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40712
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCT8 is perturbed and the expression of RHOD is measured. Does this perturbation cause a significant change in RHOD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCT8 is perturbed and the expression of RHOD is measured. Does this perturbation cause a significant change in RHOD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92290
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L1 is perturbed and CD68 expression is measured. Determine whether CD68 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L1 is perturbed and CD68 expression is measured. Determine whether CD68 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7509
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SKA3 is perturbed and the expression of ROBO1 is measured. Does this perturbation cause a significant change in ROBO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SKA3 is perturbed and the expression of ROBO1 is measured. Does this perturbation cause a significant change in ROBO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113130
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF236 and then measure expression of FBXW7. Does this perturbation cause a significant change in FBXW7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF236 and then measure expression of FBXW7. Does this perturbation cause a significant change in FBXW7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79424
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CRKL and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CRKL and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91764
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MCMBP is perturbed and TMEM200A expression is quantified. Does this perturbation result in a significant change in TMEM200A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MCMBP is perturbed and TMEM200A expression is quantified. Does this perturbation result in a significant change in TMEM200A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17602
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SP2 is perturbed and ANKMY2 expression is observed. Does this perturbation lead to a significant difference in ANKMY2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SP2 is perturbed and ANKMY2 expression is observed. Does this perturbation lead to a significant difference in ANKMY2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73783
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPS6 is perturbed and PLXNA1 expression is observed. Does this perturbation lead to a significant difference in PLXNA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPS6 is perturbed and PLXNA1 expression is observed. Does this perturbation lead to a significant difference in PLXNA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27663
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UPF1 is perturbed and DNAJC17 expression is quantified. Does this perturbation result in a significant change in DNAJC17 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UPF1 is perturbed and DNAJC17 expression is quantified. Does this perturbation result in a significant change in DNAJC17 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88112
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of PREPL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of PREPL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103207
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMU1 is perturbed and PEX26 expression is observed. Does this perturbation lead to a significant difference in PEX26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMU1 is perturbed and PEX26 expression is observed. Does this perturbation lead to a significant difference in PEX26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48623
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACTR1A is associated with a significant change in ERI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACTR1A is associated with a significant change in ERI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17415
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of CCDC22 is measured. Determine whether CCDC22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of CCDC22 is measured. Determine whether CCDC22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101906
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PIK3R4 is perturbed and the expression of MIR181A1HG is measured. Determine whether MIR181A1HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PIK3R4 is perturbed and the expression of MIR181A1HG is measured. Determine whether MIR181A1HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108186
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NHP2, does the expression profile of GPRC5C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NHP2, does the expression profile of GPRC5C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96417
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS10, does the expression profile of ARL5A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS10, does the expression profile of ARL5A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109897
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNRNPK is perturbed and KANSL1 expression is observed. Does this perturbation lead to a significant difference in KANSL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNRNPK is perturbed and KANSL1 expression is observed. Does this perturbation lead to a significant difference in KANSL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37463
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX3X is perturbed and the expression of ANKRD13D is measured. Determine whether ANKRD13D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDX3X is perturbed and the expression of ANKRD13D is measured. Determine whether ANKRD13D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41936
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD10 and then measure expression of GTPBP6. Does this perturbation cause a significant change in GTPBP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD10 and then measure expression of GTPBP6. Does this perturbation cause a significant change in GTPBP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70894
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL45 and then measure expression of RPL10. Does this perturbation cause a significant change in RPL10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL45 and then measure expression of RPL10. Does this perturbation cause a significant change in RPL10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116924
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL55 and then measure expression of SPG7. Does this perturbation cause a significant change in SPG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL55 and then measure expression of SPG7. Does this perturbation cause a significant change in SPG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79524
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TEAD3 is perturbed and the expression of HAUS3 is measured. Does this perturbation cause a significant change in HAUS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TEAD3 is perturbed and the expression of HAUS3 is measured. Does this perturbation cause a significant change in HAUS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35110
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX29 is perturbed and the expression of PBX3 is measured. Does this perturbation cause a significant change in PBX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX29 is perturbed and the expression of PBX3 is measured. Does this perturbation cause a significant change in PBX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82740
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YRDC is perturbed and the expression of POLR2G is measured. Determine whether POLR2G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YRDC is perturbed and the expression of POLR2G is measured. Determine whether POLR2G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18416
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COX6C and monitor ZFYVE9 expression. Decide whether this perturbation leads to a significant alteration in ZFYVE9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COX6C and monitor ZFYVE9 expression. Decide whether this perturbation leads to a significant alteration in ZFYVE9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70978
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARPC2 is perturbed and PPIB expression is measured. Determine whether PPIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARPC2 is perturbed and PPIB expression is measured. Determine whether PPIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52989
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NELFCD is perturbed and SINHCAF expression is measured. Determine whether SINHCAF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NELFCD is perturbed and SINHCAF expression is measured. Determine whether SINHCAF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46569
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SP2. Does perturbing MTHFD1 lead to a significant change in SP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SP2. Does perturbing MTHFD1 lead to a significant change in SP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88421
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPMT1 is associated with a significant change in ST7L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPMT1 is associated with a significant change in ST7L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18645
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCDC137 and examine the expression of GOLGB1. Does perturbing CCDC137 lead to a significant change in GOLGB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCDC137 and examine the expression of GOLGB1. Does perturbing CCDC137 lead to a significant change in GOLGB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41241
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHMP7 is perturbed and TSPAN4 expression is measured. Determine whether TSPAN4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHMP7 is perturbed and TSPAN4 expression is measured. Determine whether TSPAN4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101849
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBE2H is perturbed and the expression of AKT2 is measured. Does this perturbation cause a significant change in AKT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBE2H is perturbed and the expression of AKT2 is measured. Does this perturbation cause a significant change in AKT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30620
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FBLIM1 is perturbed and BORCS8 expression is measured. Determine whether BORCS8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FBLIM1 is perturbed and BORCS8 expression is measured. Determine whether BORCS8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27319
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC1 and then measure expression of FUCA2. Does this perturbation cause a significant change in FUCA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMC1 and then measure expression of FUCA2. Does this perturbation cause a significant change in FUCA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77094
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RBMX and then measure expression of NIPSNAP1. Does this perturbation cause a significant change in NIPSNAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RBMX and then measure expression of NIPSNAP1. Does this perturbation cause a significant change in NIPSNAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37324
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC8 and then measure expression of LPCAT1. Does this perturbation cause a significant change in LPCAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC8 and then measure expression of LPCAT1. Does this perturbation cause a significant change in LPCAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17204
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDK9 is perturbed and the expression of SNAI1 is measured. Does this perturbation cause a significant change in SNAI1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDK9 is perturbed and the expression of SNAI1 is measured. Does this perturbation cause a significant change in SNAI1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71680
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GEMIN8, does the expression profile of AIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GEMIN8, does the expression profile of AIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82137
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of GNB4 is measured. Determine whether GNB4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DR1 is perturbed and the expression of GNB4 is measured. Determine whether GNB4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121366
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPME1, does the expression profile of RPS15A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPME1, does the expression profile of RPS15A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31787
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of TTC37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of TTC37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32467
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR2D is perturbed and the expression of AP5B1 is measured. Does this perturbation cause a significant change in AP5B1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR2D is perturbed and the expression of AP5B1 is measured. Does this perturbation cause a significant change in AP5B1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":370
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMG2 and then measure expression of BLCAP. Does this perturbation cause a significant change in BLCAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMG2 and then measure expression of BLCAP. Does this perturbation cause a significant change in BLCAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82254
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PABPC4 and examine the expression of SNX29. Does perturbing PABPC4 lead to a significant change in SNX29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PABPC4 and examine the expression of SNX29. Does perturbing PABPC4 lead to a significant change in SNX29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35081
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GUK1 is perturbed and the expression of GATA6 is measured. Determine whether GATA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GUK1 is perturbed and the expression of GATA6 is measured. Determine whether GATA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49666
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CYFIP1 and examine the expression of MBD5. Does perturbing CYFIP1 lead to a significant change in MBD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CYFIP1 and examine the expression of MBD5. Does perturbing CYFIP1 lead to a significant change in MBD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108041
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK9 and then measure expression of PHC3. Does this perturbation cause a significant change in PHC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK9 and then measure expression of PHC3. Does this perturbation cause a significant change in PHC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71674
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS20 is perturbed and the expression of GINM1 is measured. Does this perturbation cause a significant change in GINM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS20 is perturbed and the expression of GINM1 is measured. Does this perturbation cause a significant change in GINM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84950
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of TAF1B. Does perturbing MRPL39 lead to a significant change in TAF1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of TAF1B. Does perturbing MRPL39 lead to a significant change in TAF1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55841
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPE1 is perturbed and RNPEP expression is quantified. Does this perturbation result in a significant change in RNPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPE1 is perturbed and RNPEP expression is quantified. Does this perturbation result in a significant change in RNPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32972
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPP1CA, does the expression profile of ZNF672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPP1CA, does the expression profile of ZNF672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40777
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX10 is associated with a significant change in PREPL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX10 is associated with a significant change in PREPL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120045
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LDB1 and monitor AASS expression. Decide whether this perturbation leads to a significant alteration in AASS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LDB1 and monitor AASS expression. Decide whether this perturbation leads to a significant alteration in AASS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111058
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OPA1 is perturbed and the expression of UBE3B is measured. Does this perturbation cause a significant change in UBE3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OPA1 is perturbed and the expression of UBE3B is measured. Does this perturbation cause a significant change in UBE3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72690
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ALYREF and then measure expression of ANXA6. Does this perturbation cause a significant change in ANXA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ALYREF and then measure expression of ANXA6. Does this perturbation cause a significant change in ANXA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40594
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PHAX is perturbed and FAM200B expression is measured. Determine whether FAM200B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PHAX is perturbed and FAM200B expression is measured. Determine whether FAM200B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20589
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RMI1 and examine the expression of TRMU. Does perturbing RMI1 lead to a significant change in TRMU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RMI1 and examine the expression of TRMU. Does perturbing RMI1 lead to a significant change in TRMU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85581
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PFDN2, does the expression profile of YIPF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PFDN2, does the expression profile of YIPF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91137
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb THUMPD1 and monitor SMIM10L1 expression. Decide whether this perturbation leads to a significant alteration in SMIM10L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb THUMPD1 and monitor SMIM10L1 expression. Decide whether this perturbation leads to a significant alteration in SMIM10L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121908
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOD1 is perturbed and CDK5RAP1 expression is observed. Does this perturbation lead to a significant difference in CDK5RAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOD1 is perturbed and CDK5RAP1 expression is observed. Does this perturbation lead to a significant difference in CDK5RAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120473
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC26, does the expression profile of SYNGR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC26, does the expression profile of SYNGR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117727
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHX29, does the expression profile of ATP6V0A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHX29, does the expression profile of ATP6V0A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82787
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLI4 is perturbed and the expression of URGCP is measured. Does this perturbation cause a significant change in URGCP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLI4 is perturbed and the expression of URGCP is measured. Does this perturbation cause a significant change in URGCP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19100
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3L is associated with a significant change in SH3D19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3L is associated with a significant change in SH3D19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9395
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPIE and then measure expression of ETV5. Does this perturbation cause a significant change in ETV5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPIE and then measure expression of ETV5. Does this perturbation cause a significant change in ETV5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116814
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLBP and examine the expression of PIGM. Does perturbing SLBP lead to a significant change in PIGM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLBP and examine the expression of PIGM. Does perturbing SLBP lead to a significant change in PIGM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120981
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ANKRD17 is perturbed and the expression of IP6K2 is measured. Does this perturbation cause a significant change in IP6K2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ANKRD17 is perturbed and the expression of IP6K2 is measured. Does this perturbation cause a significant change in IP6K2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90240
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL35A is perturbed and the expression of SAMD1 is measured. Determine whether SAMD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPL35A is perturbed and the expression of SAMD1 is measured. Determine whether SAMD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61836
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX37 is perturbed and the expression of SH3D21 is measured. Does this perturbation cause a significant change in SH3D21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHX37 is perturbed and the expression of SH3D21 is measured. Does this perturbation cause a significant change in SH3D21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91900
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PIK3R4 and monitor FAM149B1 expression. Decide whether this perturbation leads to a significant alteration in FAM149B1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PIK3R4 and monitor FAM149B1 expression. Decide whether this perturbation leads to a significant alteration in FAM149B1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108208
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED7 and examine the expression of SEC22B. Does perturbing MED7 lead to a significant change in SEC22B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED7 and examine the expression of SEC22B. Does perturbing MED7 lead to a significant change in SEC22B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106501
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HAUS3 is perturbed and CRNKL1 expression is quantified. Does this perturbation result in a significant change in CRNKL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HAUS3 is perturbed and CRNKL1 expression is quantified. Does this perturbation result in a significant change in CRNKL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":752
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MMGT1 and then measure expression of IK. Does this perturbation cause a significant change in IK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MMGT1 and then measure expression of IK. Does this perturbation cause a significant change in IK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21774
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT3 and examine the expression of ZDHHC8. Does perturbing ZNHIT3 lead to a significant change in ZDHHC8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT3 and examine the expression of ZDHHC8. Does perturbing ZNHIT3 lead to a significant change in ZDHHC8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48241
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb VPS29 and monitor SLC35B3 expression. Decide whether this perturbation leads to a significant alteration in SLC35B3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb VPS29 and monitor SLC35B3 expression. Decide whether this perturbation leads to a significant alteration in SLC35B3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67408
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CASC3 and then measure expression of GORAB. Does this perturbation cause a significant change in GORAB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CASC3 and then measure expression of GORAB. Does this perturbation cause a significant change in GORAB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16114
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP153 and examine the expression of SLC41A3. Does perturbing NUP153 lead to a significant change in SLC41A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP153 and examine the expression of SLC41A3. Does perturbing NUP153 lead to a significant change in SLC41A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13281
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSTF1 is associated with a significant change in DMKN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSTF1 is associated with a significant change in DMKN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75875
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSG1 is perturbed and the expression of NGRN is measured. Does this perturbation cause a significant change in NGRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSG1 is perturbed and the expression of NGRN is measured. Does this perturbation cause a significant change in NGRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99170
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYC and examine the expression of GLCE. Does perturbing MYC lead to a significant change in GLCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MYC and examine the expression of GLCE. Does perturbing MYC lead to a significant change in GLCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62121
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS30 and examine the expression of SNX24. Does perturbing MRPS30 lead to a significant change in SNX24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS30 and examine the expression of SNX24. Does perturbing MRPS30 lead to a significant change in SNX24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29691
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDK11A and examine the expression of PNRC1. Does perturbing CDK11A lead to a significant change in PNRC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDK11A and examine the expression of PNRC1. Does perturbing CDK11A lead to a significant change in PNRC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48531
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS25 is perturbed and NDUFAF8 expression is quantified. Does this perturbation result in a significant change in NDUFAF8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS25 is perturbed and NDUFAF8 expression is quantified. Does this perturbation result in a significant change in NDUFAF8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122442
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUP107 and then measure expression of SIL1. Does this perturbation cause a significant change in SIL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NUP107 and then measure expression of SIL1. Does this perturbation cause a significant change in SIL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83944
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF5A and examine the expression of TNS3. Does perturbing EIF5A lead to a significant change in TNS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF5A and examine the expression of TNS3. Does perturbing EIF5A lead to a significant change in TNS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81811
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIPEP is perturbed and the expression of NMD3 is measured. Determine whether NMD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIPEP is perturbed and the expression of NMD3 is measured. Determine whether NMD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66476
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NSUN4 is perturbed and the expression of GAK is measured. Determine whether GAK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NSUN4 is perturbed and the expression of GAK is measured. Determine whether GAK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10726
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MED14 and monitor WIPF2 expression. Decide whether this perturbation leads to a significant alteration in WIPF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MED14 and monitor WIPF2 expression. Decide whether this perturbation leads to a significant alteration in WIPF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41378
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LRPPRC is perturbed and ACTL6A expression is measured. Determine whether ACTL6A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LRPPRC is perturbed and ACTL6A expression is measured. Determine whether ACTL6A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75829
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, WBP1 is perturbed and the expression of HYOU1 is measured. Does this perturbation cause a significant change in HYOU1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, WBP1 is perturbed and the expression of HYOU1 is measured. Does this perturbation cause a significant change in HYOU1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF1 is associated with a significant change in DNAJB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF1 is associated with a significant change in DNAJB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38675
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HARS2 and monitor GADD45A expression. Decide whether this perturbation leads to a significant alteration in GADD45A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HARS2 and monitor GADD45A expression. Decide whether this perturbation leads to a significant alteration in GADD45A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35668
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and TMEM63B expression is observed. Does this perturbation lead to a significant difference in TMEM63B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and TMEM63B expression is observed. Does this perturbation lead to a significant difference in TMEM63B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90383
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2I and examine the expression of CHID1. Does perturbing POLR2I lead to a significant change in CHID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2I and examine the expression of CHID1. Does perturbing POLR2I lead to a significant change in CHID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16901
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMG2 is perturbed and the expression of PARG is measured. Determine whether PARG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMG2 is perturbed and the expression of PARG is measured. Determine whether PARG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82306
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBTF is perturbed and SNHG30 expression is quantified. Does this perturbation result in a significant change in SNHG30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBTF is perturbed and SNHG30 expression is quantified. Does this perturbation result in a significant change in SNHG30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4212
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80D is perturbed and NAGK expression is quantified. Does this perturbation result in a significant change in NAGK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80D is perturbed and NAGK expression is quantified. Does this perturbation result in a significant change in NAGK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54682
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED14 and then measure expression of GABARAPL1. Does this perturbation cause a significant change in GABARAPL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED14 and then measure expression of GABARAPL1. Does this perturbation cause a significant change in GABARAPL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41384
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CINP is perturbed and LIG4 expression is observed. Does this perturbation lead to a significant difference in LIG4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CINP is perturbed and LIG4 expression is observed. Does this perturbation lead to a significant difference in LIG4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97103
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPP2CB and monitor ATXN7 expression. Decide whether this perturbation leads to a significant alteration in ATXN7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPP2CB and monitor ATXN7 expression. Decide whether this perturbation leads to a significant alteration in ATXN7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10138
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF236 is perturbed and FBXW7 expression is observed. Does this perturbation lead to a significant difference in FBXW7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF236 is perturbed and FBXW7 expression is observed. Does this perturbation lead to a significant difference in FBXW7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79423
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUB1B is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUB1B is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77815
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SS18L2 and monitor ABHD10 expression. Decide whether this perturbation leads to a significant alteration in ABHD10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SS18L2 and monitor ABHD10 expression. Decide whether this perturbation leads to a significant alteration in ABHD10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22748
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT6 and examine the expression of GSTZ1. Does perturbing TRMT6 lead to a significant change in GSTZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT6 and examine the expression of GSTZ1. Does perturbing TRMT6 lead to a significant change in GSTZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83371
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VARS and then measure expression of KRCC1. Does this perturbation cause a significant change in KRCC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VARS and then measure expression of KRCC1. Does this perturbation cause a significant change in KRCC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10344
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF10, does the expression profile of KAT6B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAF10, does the expression profile of KAT6B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122077
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KRT10 and monitor KPNA6 expression. Decide whether this perturbation leads to a significant alteration in KPNA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KRT10 and monitor KPNA6 expression. Decide whether this perturbation leads to a significant alteration in KPNA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30408
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS6 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS6 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89342
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MCM3AP is perturbed and the expression of PLAAT4 is measured. Does this perturbation cause a significant change in PLAAT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MCM3AP is perturbed and the expression of PLAAT4 is measured. Does this perturbation cause a significant change in PLAAT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52720
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF787 and monitor PRKX expression. Decide whether this perturbation leads to a significant alteration in PRKX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF787 and monitor PRKX expression. Decide whether this perturbation leads to a significant alteration in PRKX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102308
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2K, does the expression profile of APBB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2K, does the expression profile of APBB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5887
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS8 is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPS8 is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118260
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRELID1 is associated with a significant change in GABARAPL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRELID1 is associated with a significant change in GABARAPL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60795
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRNP27 and then measure expression of UBE2W. Does this perturbation cause a significant change in UBE2W expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNRNP27 and then measure expression of UBE2W. Does this perturbation cause a significant change in UBE2W expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72174
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IWS1 and monitor INIP expression. Decide whether this perturbation leads to a significant alteration in INIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IWS1 and monitor INIP expression. Decide whether this perturbation leads to a significant alteration in INIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67908
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VMP1 is associated with a significant change in RAB11A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of VMP1 is associated with a significant change in RAB11A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88985
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX17 and then measure expression of GRAMD1A. Does this perturbation cause a significant change in GRAMD1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX17 and then measure expression of GRAMD1A. Does this perturbation cause a significant change in GRAMD1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12524
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SERBP1 is perturbed and INTS3 expression is quantified. Does this perturbation result in a significant change in INTS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SERBP1 is perturbed and INTS3 expression is quantified. Does this perturbation result in a significant change in INTS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1352
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZFR, does the expression profile of PEX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZFR, does the expression profile of PEX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65297
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFA6 is perturbed and AOX1 expression is measured. Determine whether AOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFA6 is perturbed and AOX1 expression is measured. Determine whether AOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38809
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TXNL4B is perturbed and ETF1 expression is observed. Does this perturbation lead to a significant difference in ETF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TXNL4B is perturbed and ETF1 expression is observed. Does this perturbation lead to a significant difference in ETF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26133
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL10A and examine the expression of SMG7. Does perturbing RPL10A lead to a significant change in SMG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL10A and examine the expression of SMG7. Does perturbing RPL10A lead to a significant change in SMG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87441
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPLP2, does the expression profile of SIK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPLP2, does the expression profile of SIK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90347
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMC6 and monitor EZH1 expression. Decide whether this perturbation leads to a significant alteration in EZH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMC6 and monitor EZH1 expression. Decide whether this perturbation leads to a significant alteration in EZH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102358
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMAGP is perturbed and CDCP1 expression is observed. Does this perturbation lead to a significant difference in CDCP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMAGP is perturbed and CDCP1 expression is observed. Does this perturbation lead to a significant difference in CDCP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63543
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSAT1 is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSAT1 is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69199
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GON4L and examine the expression of ORMDL2. Does perturbing GON4L lead to a significant change in ORMDL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GON4L and examine the expression of ORMDL2. Does perturbing GON4L lead to a significant change in ORMDL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64961
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ICE1 is perturbed and HELQ expression is measured. Determine whether HELQ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ICE1 is perturbed and HELQ expression is measured. Determine whether HELQ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30369
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BRIP1 is perturbed and the expression of RHOA is measured. Determine whether RHOA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BRIP1 is perturbed and the expression of RHOA is measured. Determine whether RHOA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51976
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBMX2, does the expression profile of METTL16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBMX2, does the expression profile of METTL16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51817
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUB1 and then measure expression of SPIRE1. Does this perturbation cause a significant change in SPIRE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BUB1 and then measure expression of SPIRE1. Does this perturbation cause a significant change in SPIRE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78384
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARPC1B is associated with a significant change in BCL2L13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARPC1B is associated with a significant change in BCL2L13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58915
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BNIP1 and monitor TSLP expression. Decide whether this perturbation leads to a significant alteration in TSLP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BNIP1 and monitor TSLP expression. Decide whether this perturbation leads to a significant alteration in TSLP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82618
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MT2A is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MT2A is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104995
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD17 is associated with a significant change in PTGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD17 is associated with a significant change in PTGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90275
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPS4 is perturbed and RNF169 expression is observed. Does this perturbation lead to a significant difference in RNF169 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPS4 is perturbed and RNF169 expression is observed. Does this perturbation lead to a significant difference in RNF169 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119743
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ACTR1B and monitor LINC00511 expression. Decide whether this perturbation leads to a significant alteration in LINC00511 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ACTR1B and monitor LINC00511 expression. Decide whether this perturbation leads to a significant alteration in LINC00511 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66338
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GAPDH is associated with a significant change in MRTO4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GAPDH is associated with a significant change in MRTO4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54485
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSME1 and then measure expression of SYNJ2BP. Does this perturbation cause a significant change in SYNJ2BP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSME1 and then measure expression of SYNJ2BP. Does this perturbation cause a significant change in SYNJ2BP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35284
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DSN1 is perturbed and the expression of CYFIP2 is measured. Does this perturbation cause a significant change in CYFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DSN1 is perturbed and the expression of CYFIP2 is measured. Does this perturbation cause a significant change in CYFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96670
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OPA1 is perturbed and SEM1 expression is quantified. Does this perturbation result in a significant change in SEM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OPA1 is perturbed and SEM1 expression is quantified. Does this perturbation result in a significant change in SEM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72682
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPF1 is associated with a significant change in NUDT9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPF1 is associated with a significant change in NUDT9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94365
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC3 is perturbed and RPS18 expression is observed. Does this perturbation lead to a significant difference in RPS18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC3 is perturbed and RPS18 expression is observed. Does this perturbation lead to a significant difference in RPS18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50473
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCKAP1 is associated with a significant change in CCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCKAP1 is associated with a significant change in CCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32905
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTNNBL1, does the expression profile of HIST3H2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTNNBL1, does the expression profile of HIST3H2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30567
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX41 is perturbed and DCAF10 expression is quantified. Does this perturbation result in a significant change in DCAF10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX41 is perturbed and DCAF10 expression is quantified. Does this perturbation result in a significant change in DCAF10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104462
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RNF168 is perturbed and NOVA1 expression is quantified. Does this perturbation result in a significant change in NOVA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RNF168 is perturbed and NOVA1 expression is quantified. Does this perturbation result in a significant change in NOVA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100922
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VEZT and then measure expression of EFL1. Does this perturbation cause a significant change in EFL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VEZT and then measure expression of EFL1. Does this perturbation cause a significant change in EFL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67754
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ADAM10 is perturbed and the expression of COG6 is measured. Does this perturbation cause a significant change in COG6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ADAM10 is perturbed and the expression of COG6 is measured. Does this perturbation cause a significant change in COG6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15590
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTK is perturbed and CHM expression is measured. Determine whether CHM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTK is perturbed and CHM expression is measured. Determine whether CHM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17589
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GSK3B is perturbed and UQCC1 expression is observed. Does this perturbation lead to a significant difference in UQCC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GSK3B is perturbed and UQCC1 expression is observed. Does this perturbation lead to a significant difference in UQCC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38483
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DYNLRB1 is perturbed and STAT2 expression is measured. Determine whether STAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DYNLRB1 is perturbed and STAT2 expression is measured. Determine whether STAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67059
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAFAH1B1 is associated with a significant change in GPNMB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAFAH1B1 is associated with a significant change in GPNMB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91345
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEM1 is associated with a significant change in HHIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEM1 is associated with a significant change in HHIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80615
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RFT1 is perturbed and the expression of KANSL2 is measured. Does this perturbation cause a significant change in KANSL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RFT1 is perturbed and the expression of KANSL2 is measured. Does this perturbation cause a significant change in KANSL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31300
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS12 is perturbed and the expression of ZNF574 is measured. Does this perturbation cause a significant change in ZNF574 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS12 is perturbed and the expression of ZNF574 is measured. Does this perturbation cause a significant change in ZNF574 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117700
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJA3 is associated with a significant change in RMI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJA3 is associated with a significant change in RMI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29115
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STRIP1 is perturbed and GSDMD expression is quantified. Does this perturbation result in a significant change in GSDMD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STRIP1 is perturbed and GSDMD expression is quantified. Does this perturbation result in a significant change in GSDMD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37532
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TXNL4B is perturbed and DNAJC8 expression is quantified. Does this perturbation result in a significant change in DNAJC8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TXNL4B is perturbed and DNAJC8 expression is quantified. Does this perturbation result in a significant change in DNAJC8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26112
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FASN and examine the expression of DMD. Does perturbing FASN lead to a significant change in DMD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FASN and examine the expression of DMD. Does perturbing FASN lead to a significant change in DMD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114221
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EPB41L2 and then measure expression of METTL16. Does this perturbation cause a significant change in METTL16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EPB41L2 and then measure expression of METTL16. Does this perturbation cause a significant change in METTL16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35404
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMC2 is perturbed and DMXL2 expression is measured. Determine whether DMXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMC2 is perturbed and DMXL2 expression is measured. Determine whether DMXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101239
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and C1orf50 expression is quantified. Does this perturbation result in a significant change in C1orf50 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and C1orf50 expression is quantified. Does this perturbation result in a significant change in C1orf50 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44582
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFS3 is perturbed and CLHC1 expression is quantified. Does this perturbation result in a significant change in CLHC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFS3 is perturbed and CLHC1 expression is quantified. Does this perturbation result in a significant change in CLHC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6512
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSA and then measure expression of SMURF2. Does this perturbation cause a significant change in SMURF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSA and then measure expression of SMURF2. Does this perturbation cause a significant change in SMURF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61744
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF706 is perturbed and MOSPD2 expression is observed. Does this perturbation lead to a significant difference in MOSPD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF706 is perturbed and MOSPD2 expression is observed. Does this perturbation lead to a significant difference in MOSPD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18863
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPP1CA is perturbed and SUGCT expression is quantified. Does this perturbation result in a significant change in SUGCT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPP1CA is perturbed and SUGCT expression is quantified. Does this perturbation result in a significant change in SUGCT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40742
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS14 is perturbed and the expression of TRIM16L is measured. Determine whether TRIM16L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS14 is perturbed and the expression of TRIM16L is measured. Determine whether TRIM16L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43136
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WARS, does the expression profile of NNT-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WARS, does the expression profile of NNT-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73507
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EPRS is associated with a significant change in BTF3L4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EPRS is associated with a significant change in BTF3L4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100415
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBX1 is perturbed and the expression of DNAJB14 is measured. Does this perturbation cause a significant change in DNAJB14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RBX1 is perturbed and the expression of DNAJB14 is measured. Does this perturbation cause a significant change in DNAJB14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57110
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF7 is associated with a significant change in ABHD14A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF7 is associated with a significant change in ABHD14A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115155
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, H2AFX is perturbed and the expression of ROR1 is measured. Does this perturbation cause a significant change in ROR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, H2AFX is perturbed and the expression of ROR1 is measured. Does this perturbation cause a significant change in ROR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93340
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NRDE2 is perturbed and LRP11 expression is measured. Determine whether LRP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NRDE2 is perturbed and LRP11 expression is measured. Determine whether LRP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77249
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR1C is perturbed and the expression of SLC25A12 is measured. Does this perturbation cause a significant change in SLC25A12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POLR1C is perturbed and the expression of SLC25A12 is measured. Does this perturbation cause a significant change in SLC25A12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60600
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EPRS and examine the expression of SAT1. Does perturbing EPRS lead to a significant change in SAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EPRS and examine the expression of SAT1. Does perturbing EPRS lead to a significant change in SAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100381
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MZT1 and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MZT1 and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104098
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RAC1 is perturbed and the expression of ATP6AP1 is measured. Does this perturbation cause a significant change in ATP6AP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RAC1 is perturbed and the expression of ATP6AP1 is measured. Does this perturbation cause a significant change in ATP6AP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110810
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KAT7 is perturbed and MOB1A expression is measured. Determine whether MOB1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KAT7 is perturbed and MOB1A expression is measured. Determine whether MOB1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84689
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LONP1 and examine the expression of MRPL10. Does perturbing LONP1 lead to a significant change in MRPL10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LONP1 and examine the expression of MRPL10. Does perturbing LONP1 lead to a significant change in MRPL10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77151
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EMC7 and examine the expression of TMA7. Does perturbing EMC7 lead to a significant change in TMA7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EMC7 and examine the expression of TMA7. Does perturbing EMC7 lead to a significant change in TMA7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8951
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KANSL2 is perturbed and the expression of WDR13 is measured. Does this perturbation cause a significant change in WDR13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KANSL2 is perturbed and the expression of WDR13 is measured. Does this perturbation cause a significant change in WDR13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82410
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CYFIP1 is perturbed and the expression of FBXO32 is measured. Does this perturbation cause a significant change in FBXO32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CYFIP1 is perturbed and the expression of FBXO32 is measured. Does this perturbation cause a significant change in FBXO32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108010
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK2 and then measure expression of SIRT2. Does this perturbation cause a significant change in SIRT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDK2 and then measure expression of SIRT2. Does this perturbation cause a significant change in SIRT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66694
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRPD2 is perturbed and MDM4 expression is observed. Does this perturbation lead to a significant difference in MDM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRPD2 is perturbed and MDM4 expression is observed. Does this perturbation lead to a significant difference in MDM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107603
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ACTB and examine the expression of TPD52L1. Does perturbing ACTB lead to a significant change in TPD52L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ACTB and examine the expression of TPD52L1. Does perturbing ACTB lead to a significant change in TPD52L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":261
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, METAP1 is perturbed and TLE1 expression is measured. Determine whether TLE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, METAP1 is perturbed and TLE1 expression is measured. Determine whether TLE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107969
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DNMT1 and monitor ATP10D expression. Decide whether this perturbation leads to a significant alteration in ATP10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNMT1 and monitor ATP10D expression. Decide whether this perturbation leads to a significant alteration in ATP10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100658
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RFC3, does the expression profile of NREP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RFC3, does the expression profile of NREP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37627
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCT7 is perturbed and the expression of ORC3 is measured. Determine whether ORC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCT7 is perturbed and the expression of ORC3 is measured. Determine whether ORC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87826
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COX5A is perturbed and WDR45 expression is quantified. Does this perturbation result in a significant change in WDR45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COX5A is perturbed and WDR45 expression is quantified. Does this perturbation result in a significant change in WDR45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3072
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KDM2A is perturbed and the expression of LAPTM4B is measured. Does this perturbation cause a significant change in LAPTM4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KDM2A is perturbed and the expression of LAPTM4B is measured. Does this perturbation cause a significant change in LAPTM4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3550
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR3H and then measure expression of PPP1R11. Does this perturbation cause a significant change in PPP1R11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POLR3H and then measure expression of PPP1R11. Does this perturbation cause a significant change in PPP1R11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54574
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PMPCB is perturbed and the expression of CPE is measured. Determine whether CPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PMPCB is perturbed and the expression of CPE is measured. Determine whether CPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59466
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COG2 and then measure expression of DDX6. Does this perturbation cause a significant change in DDX6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COG2 and then measure expression of DDX6. Does this perturbation cause a significant change in DDX6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10634
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ERH and monitor SNHG17 expression. Decide whether this perturbation leads to a significant alteration in SNHG17 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ERH and monitor SNHG17 expression. Decide whether this perturbation leads to a significant alteration in SNHG17 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109488
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL4 and examine the expression of ASH1L. Does perturbing RPL4 lead to a significant change in ASH1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL4 and examine the expression of ASH1L. Does perturbing RPL4 lead to a significant change in ASH1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96221
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DCAF6 and then measure expression of COA7. Does this perturbation cause a significant change in COA7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DCAF6 and then measure expression of COA7. Does this perturbation cause a significant change in COA7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6554
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STX18 and monitor NR1H2 expression. Decide whether this perturbation leads to a significant alteration in NR1H2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STX18 and monitor NR1H2 expression. Decide whether this perturbation leads to a significant alteration in NR1H2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30698
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TWNK is perturbed and MPST expression is quantified. Does this perturbation result in a significant change in MPST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TWNK is perturbed and MPST expression is quantified. Does this perturbation result in a significant change in MPST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26232
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR55 is perturbed and the expression of XYLT1 is measured. Does this perturbation cause a significant change in XYLT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR55 is perturbed and the expression of XYLT1 is measured. Does this perturbation cause a significant change in XYLT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122620
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEPCE, does the expression profile of TRAK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEPCE, does the expression profile of TRAK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109327
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NSA2 is perturbed and CSNK2B expression is measured. Determine whether CSNK2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NSA2 is perturbed and CSNK2B expression is measured. Determine whether CSNK2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59439
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL15 is perturbed and the expression of BRAT1 is measured. Determine whether BRAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL15 is perturbed and the expression of BRAT1 is measured. Determine whether BRAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46246
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PCID2 is perturbed and DHRS7 expression is quantified. Does this perturbation result in a significant change in DHRS7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PCID2 is perturbed and DHRS7 expression is quantified. Does this perturbation result in a significant change in DHRS7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34822
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1A is perturbed and EPHX4 expression is measured. Determine whether EPHX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1A is perturbed and EPHX4 expression is measured. Determine whether EPHX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92869
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL44 is perturbed and CYB5A expression is quantified. Does this perturbation result in a significant change in CYB5A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL44 is perturbed and CYB5A expression is quantified. Does this perturbation result in a significant change in CYB5A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87682
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4A1 is perturbed and MLH3 expression is measured. Determine whether MLH3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF4A1 is perturbed and MLH3 expression is measured. Determine whether MLH3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111579
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to H3F3A and then measure expression of NDUFA12. Does this perturbation cause a significant change in NDUFA12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to H3F3A and then measure expression of NDUFA12. Does this perturbation cause a significant change in NDUFA12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3184
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MCMBP and examine the expression of DHRS4. Does perturbing MCMBP lead to a significant change in DHRS4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MCMBP and examine the expression of DHRS4. Does perturbing MCMBP lead to a significant change in DHRS4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17651
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CWC25 is perturbed and the expression of RND3 is measured. Does this perturbation cause a significant change in RND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CWC25 is perturbed and the expression of RND3 is measured. Does this perturbation cause a significant change in RND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65210
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSR1 is perturbed and the expression of PBX1 is measured. Determine whether PBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSR1 is perturbed and the expression of PBX1 is measured. Determine whether PBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7106
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL10A is perturbed and the expression of ISG15 is measured. Does this perturbation cause a significant change in ISG15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPL10A is perturbed and the expression of ISG15 is measured. Does this perturbation cause a significant change in ISG15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87410
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD11 and examine the expression of MIDN. Does perturbing ABHD11 lead to a significant change in MIDN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD11 and examine the expression of MIDN. Does perturbing ABHD11 lead to a significant change in MIDN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36751
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INO80C and examine the expression of COPE. Does perturbing INO80C lead to a significant change in COPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INO80C and examine the expression of COPE. Does perturbing INO80C lead to a significant change in COPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27211
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCBP1 is perturbed and the expression of RANGRF is measured. Does this perturbation cause a significant change in RANGRF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCBP1 is perturbed and the expression of RANGRF is measured. Does this perturbation cause a significant change in RANGRF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62900
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CRKL is perturbed and MBOAT2 expression is quantified. Does this perturbation result in a significant change in MBOAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CRKL is perturbed and MBOAT2 expression is quantified. Does this perturbation result in a significant change in MBOAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91782
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INO80E is perturbed and the expression of KDM4B is measured. Determine whether KDM4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INO80E is perturbed and the expression of KDM4B is measured. Determine whether KDM4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61066
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR82 and examine the expression of APH1B. Does perturbing WDR82 lead to a significant change in APH1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR82 and examine the expression of APH1B. Does perturbing WDR82 lead to a significant change in APH1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111201
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HMGN2 is perturbed and AGAP3 expression is quantified. Does this perturbation result in a significant change in AGAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HMGN2 is perturbed and AGAP3 expression is quantified. Does this perturbation result in a significant change in AGAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52922
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRCA1 and examine the expression of AL627171.2. Does perturbing BRCA1 lead to a significant change in AL627171.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRCA1 and examine the expression of AL627171.2. Does perturbing BRCA1 lead to a significant change in AL627171.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121711
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KANSL1 is perturbed and SPTLC1 expression is observed. Does this perturbation lead to a significant difference in SPTLC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KANSL1 is perturbed and SPTLC1 expression is observed. Does this perturbation lead to a significant difference in SPTLC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102643
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MCMBP is perturbed and the expression of TULP4 is measured. Does this perturbation cause a significant change in TULP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MCMBP is perturbed and the expression of TULP4 is measured. Does this perturbation cause a significant change in TULP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17610
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KAT5 and monitor SASH1 expression. Decide whether this perturbation leads to a significant alteration in SASH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KAT5 and monitor SASH1 expression. Decide whether this perturbation leads to a significant alteration in SASH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84088
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC86, does the expression profile of SIRT6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCDC86, does the expression profile of SIRT6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108167
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPE1, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPE1, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32967
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CASC3 is associated with a significant change in RARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CASC3 is associated with a significant change in RARS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16135
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NELFCD is perturbed and CHST11 expression is measured. Determine whether CHST11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NELFCD is perturbed and CHST11 expression is measured. Determine whether CHST11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46539
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KDM1A is perturbed and MPHOSPH8 expression is quantified. Does this perturbation result in a significant change in MPHOSPH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KDM1A is perturbed and MPHOSPH8 expression is quantified. Does this perturbation result in a significant change in MPHOSPH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41082
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COX6C and monitor SPIDR expression. Decide whether this perturbation leads to a significant alteration in SPIDR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COX6C and monitor SPIDR expression. Decide whether this perturbation leads to a significant alteration in SPIDR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71018
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NKAPD1 is perturbed and TRIM26 expression is quantified. Does this perturbation result in a significant change in TRIM26 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NKAPD1 is perturbed and TRIM26 expression is quantified. Does this perturbation result in a significant change in TRIM26 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21242
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SF3B5 is perturbed and KRTCAP2 expression is measured. Determine whether KRTCAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SF3B5 is perturbed and KRTCAP2 expression is measured. Determine whether KRTCAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16069
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80B is perturbed and ABCA1 expression is quantified. Does this perturbation result in a significant change in ABCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, INO80B is perturbed and ABCA1 expression is quantified. Does this perturbation result in a significant change in ABCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81422
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YEATS2 is perturbed and RASSF3 expression is measured. Determine whether RASSF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YEATS2 is perturbed and RASSF3 expression is measured. Determine whether RASSF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26669
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and MTURN expression is observed. Does this perturbation lead to a significant difference in MTURN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and MTURN expression is observed. Does this perturbation lead to a significant difference in MTURN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102053
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EBNA1BP2 is perturbed and IFT43 expression is measured. Determine whether IFT43 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EBNA1BP2 is perturbed and IFT43 expression is measured. Determine whether IFT43 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69739
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCNB1 is perturbed and UQCC3 expression is quantified. Does this perturbation result in a significant change in UQCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCNB1 is perturbed and UQCC3 expression is quantified. Does this perturbation result in a significant change in UQCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73952
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HIPK1 and examine the expression of BEND7. Does perturbing HIPK1 lead to a significant change in BEND7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HIPK1 and examine the expression of BEND7. Does perturbing HIPK1 lead to a significant change in BEND7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26061
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ADAM10 is perturbed and the expression of AC127502.2 is measured. Determine whether AC127502.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ADAM10 is perturbed and the expression of AC127502.2 is measured. Determine whether AC127502.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15586
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and OPA1 expression is observed. Does this perturbation lead to a significant difference in OPA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and OPA1 expression is observed. Does this perturbation lead to a significant difference in OPA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14543
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GUK1 is perturbed and TIMM10B expression is observed. Does this perturbation lead to a significant difference in TIMM10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GUK1 is perturbed and TIMM10B expression is observed. Does this perturbation lead to a significant difference in TIMM10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49703
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AFG3L2 is perturbed and the expression of HMGCL is measured. Does this perturbation cause a significant change in HMGCL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AFG3L2 is perturbed and the expression of HMGCL is measured. Does this perturbation cause a significant change in HMGCL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87950
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR75 and then measure expression of ST6GALNAC6. Does this perturbation cause a significant change in ST6GALNAC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR75 and then measure expression of ST6GALNAC6. Does this perturbation cause a significant change in ST6GALNAC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121654
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of LAMA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of LAMA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101877
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PNKP is perturbed and the expression of CAMLG is measured. Does this perturbation cause a significant change in CAMLG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PNKP is perturbed and the expression of CAMLG is measured. Does this perturbation cause a significant change in CAMLG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50170
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUF2, does the expression profile of TOR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUF2, does the expression profile of TOR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60047
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCT4 is perturbed and IFT22 expression is observed. Does this perturbation lead to a significant difference in IFT22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCT4 is perturbed and IFT22 expression is observed. Does this perturbation lead to a significant difference in IFT22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44463
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1C1 is perturbed and PRKCI expression is observed. Does this perturbation lead to a significant difference in PRKCI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1C1 is perturbed and PRKCI expression is observed. Does this perturbation lead to a significant difference in PRKCI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118443
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and RRAS expression is measured. Determine whether RRAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and RRAS expression is measured. Determine whether RRAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74819
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLA1 and examine the expression of PDP2. Does perturbing POLA1 lead to a significant change in PDP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLA1 and examine the expression of PDP2. Does perturbing POLA1 lead to a significant change in PDP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101131
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBE2M is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBE2M is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7750
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK1 is associated with a significant change in KCNQ1OT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK1 is associated with a significant change in KCNQ1OT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64315
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BUB1 is perturbed and SPIRE1 expression is measured. Determine whether SPIRE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BUB1 is perturbed and SPIRE1 expression is measured. Determine whether SPIRE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78389
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, THAP1 is perturbed and the expression of EHBP1L1 is measured. Does this perturbation cause a significant change in EHBP1L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, THAP1 is perturbed and the expression of EHBP1L1 is measured. Does this perturbation cause a significant change in EHBP1L1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20390
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC17 is perturbed and RSBN1L expression is observed. Does this perturbation lead to a significant difference in RSBN1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC17 is perturbed and RSBN1L expression is observed. Does this perturbation lead to a significant difference in RSBN1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73843
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF706 is associated with a significant change in MOSPD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF706 is associated with a significant change in MOSPD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18865
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS13 is associated with a significant change in GTF2H4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS13 is associated with a significant change in GTF2H4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56805
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS8, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS8, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20257
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF2BP2 is perturbed and the expression of PSTK is measured. Does this perturbation cause a significant change in PSTK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF2BP2 is perturbed and the expression of PSTK is measured. Does this perturbation cause a significant change in PSTK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95580
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RRP1 is perturbed and ARF3 expression is quantified. Does this perturbation result in a significant change in ARF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RRP1 is perturbed and ARF3 expression is quantified. Does this perturbation result in a significant change in ARF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115192
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPUSD4, does the expression profile of ANGPT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPUSD4, does the expression profile of ANGPT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61277
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LONP1 is perturbed and CDC42SE2 expression is measured. Determine whether CDC42SE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LONP1 is perturbed and CDC42SE2 expression is measured. Determine whether CDC42SE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77209
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBMXL1 and examine the expression of DLG3. Does perturbing RBMXL1 lead to a significant change in DLG3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBMXL1 and examine the expression of DLG3. Does perturbing RBMXL1 lead to a significant change in DLG3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10541
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, REV3L is perturbed and SOX12 expression is quantified. Does this perturbation result in a significant change in SOX12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, REV3L is perturbed and SOX12 expression is quantified. Does this perturbation result in a significant change in SOX12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56732
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAXX and then measure expression of PLA2G12A. Does this perturbation cause a significant change in PLA2G12A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAXX and then measure expression of PLA2G12A. Does this perturbation cause a significant change in PLA2G12A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52664
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM39, does the expression profile of RETREG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM39, does the expression profile of RETREG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99887
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBMX2 is perturbed and AC037198.1 expression is quantified. Does this perturbation result in a significant change in AC037198.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBMX2 is perturbed and AC037198.1 expression is quantified. Does this perturbation result in a significant change in AC037198.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51822
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CYC1 and monitor ZDHHC3 expression. Decide whether this perturbation leads to a significant alteration in ZDHHC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CYC1 and monitor ZDHHC3 expression. Decide whether this perturbation leads to a significant alteration in ZDHHC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74608
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SFSWAP and examine the expression of NTN4. Does perturbing SFSWAP lead to a significant change in NTN4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SFSWAP and examine the expression of NTN4. Does perturbing SFSWAP lead to a significant change in NTN4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84421
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CENPE is perturbed and the expression of IFNGR1 is measured. Determine whether IFNGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CENPE is perturbed and the expression of IFNGR1 is measured. Determine whether IFNGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86566
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL18 and examine the expression of NNMT. Does perturbing RPL18 lead to a significant change in NNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL18 and examine the expression of NNMT. Does perturbing RPL18 lead to a significant change in NNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82931
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCNC is perturbed and the expression of ITFG2 is measured. Determine whether ITFG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCNC is perturbed and the expression of ITFG2 is measured. Determine whether ITFG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81996
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FIP1L1 is perturbed and SUMF1 expression is measured. Determine whether SUMF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FIP1L1 is perturbed and SUMF1 expression is measured. Determine whether SUMF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121519
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIP7 is perturbed and TMED10 expression is observed. Does this perturbation lead to a significant difference in TMED10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIP7 is perturbed and TMED10 expression is observed. Does this perturbation lead to a significant difference in TMED10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93163
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1H is perturbed and BRMS1 expression is observed. Does this perturbation lead to a significant difference in BRMS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1H is perturbed and BRMS1 expression is observed. Does this perturbation lead to a significant difference in BRMS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53293
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUB1 is associated with a significant change in FBXO32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BUB1 is associated with a significant change in FBXO32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78365
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C1orf131 is perturbed and the expression of MYL9 is measured. Does this perturbation cause a significant change in MYL9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C1orf131 is perturbed and the expression of MYL9 is measured. Does this perturbation cause a significant change in MYL9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95400
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX16 and then measure expression of CBWD5. Does this perturbation cause a significant change in CBWD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX16 and then measure expression of CBWD5. Does this perturbation cause a significant change in CBWD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91684
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SDHC is perturbed and ARIH2 expression is measured. Determine whether ARIH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SDHC is perturbed and ARIH2 expression is measured. Determine whether ARIH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119349
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRMT5, does the expression profile of RGS12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRMT5, does the expression profile of RGS12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39907
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS33 and then measure expression of MRNIP. Does this perturbation cause a significant change in MRNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPS33 and then measure expression of MRNIP. Does this perturbation cause a significant change in MRNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100534
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPP4R2 and monitor ZNF433-AS1 expression. Decide whether this perturbation leads to a significant alteration in ZNF433-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPP4R2 and monitor ZNF433-AS1 expression. Decide whether this perturbation leads to a significant alteration in ZNF433-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76958
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARDBP and examine the expression of LTBP3. Does perturbing TARDBP lead to a significant change in LTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARDBP and examine the expression of LTBP3. Does perturbing TARDBP lead to a significant change in LTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6101
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS2 is perturbed and HCG18 expression is quantified. Does this perturbation result in a significant change in HCG18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS2 is perturbed and HCG18 expression is quantified. Does this perturbation result in a significant change in HCG18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35652
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP54 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP54 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121203
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOL12 and then measure expression of SH3BGRL. Does this perturbation cause a significant change in SH3BGRL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOL12 and then measure expression of SH3BGRL. Does this perturbation cause a significant change in SH3BGRL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119464
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CTR9 is perturbed and ABHD14A expression is quantified. Does this perturbation result in a significant change in ABHD14A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CTR9 is perturbed and ABHD14A expression is quantified. Does this perturbation result in a significant change in ABHD14A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120672
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRD8 is perturbed and THOC6 expression is measured. Determine whether THOC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRD8 is perturbed and THOC6 expression is measured. Determine whether THOC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93939
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TUBB is perturbed and VPS8 expression is quantified. Does this perturbation result in a significant change in VPS8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TUBB is perturbed and VPS8 expression is quantified. Does this perturbation result in a significant change in VPS8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51602
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JAZF1 and examine the expression of IFT74. Does perturbing JAZF1 lead to a significant change in IFT74 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JAZF1 and examine the expression of IFT74. Does perturbing JAZF1 lead to a significant change in IFT74 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43511
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, USP37 is perturbed and the expression of SMURF2 is measured. Does this perturbation cause a significant change in SMURF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, USP37 is perturbed and the expression of SMURF2 is measured. Does this perturbation cause a significant change in SMURF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98570
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP2A2 is perturbed and INSIG1 expression is quantified. Does this perturbation result in a significant change in INSIG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP2A2 is perturbed and INSIG1 expression is quantified. Does this perturbation result in a significant change in INSIG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83652
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC4 is perturbed and CKAP4 expression is measured. Determine whether CKAP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC4 is perturbed and CKAP4 expression is measured. Determine whether CKAP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59909
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCLAF1 and monitor DHX29 expression. Decide whether this perturbation leads to a significant alteration in DHX29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCLAF1 and monitor DHX29 expression. Decide whether this perturbation leads to a significant alteration in DHX29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108858
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB17 is perturbed and PALMD expression is observed. Does this perturbation lead to a significant difference in PALMD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB17 is perturbed and PALMD expression is observed. Does this perturbation lead to a significant difference in PALMD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45153
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG13 is perturbed and DNAJB11 expression is quantified. Does this perturbation result in a significant change in DNAJB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG13 is perturbed and DNAJB11 expression is quantified. Does this perturbation result in a significant change in DNAJB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107402
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STXBP4 and then measure expression of KRIT1. Does this perturbation cause a significant change in KRIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STXBP4 and then measure expression of KRIT1. Does this perturbation cause a significant change in KRIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22154
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KXD1 is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KXD1 is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113825
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YRDC and then measure expression of MGLL. Does this perturbation cause a significant change in MGLL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YRDC and then measure expression of MGLL. Does this perturbation cause a significant change in MGLL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18384
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNMT1 is perturbed and TMEM127 expression is observed. Does this perturbation lead to a significant difference in TMEM127 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNMT1 is perturbed and TMEM127 expression is observed. Does this perturbation lead to a significant difference in TMEM127 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100623
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1E1 is perturbed and SAT1 expression is observed. Does this perturbation lead to a significant difference in SAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V1E1 is perturbed and SAT1 expression is observed. Does this perturbation lead to a significant difference in SAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112743
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL20 and monitor PIP4K2B expression. Decide whether this perturbation leads to a significant alteration in PIP4K2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL20 and monitor PIP4K2B expression. Decide whether this perturbation leads to a significant alteration in PIP4K2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18238
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZMAT2 is perturbed and NEU1 expression is measured. Determine whether NEU1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZMAT2 is perturbed and NEU1 expression is measured. Determine whether NEU1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5159
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC4 is perturbed and G0S2 expression is observed. Does this perturbation lead to a significant difference in G0S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAPC4 is perturbed and G0S2 expression is observed. Does this perturbation lead to a significant difference in G0S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48163
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1CB is perturbed and the expression of RASSF7 is measured. Determine whether RASSF7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1CB is perturbed and the expression of RASSF7 is measured. Determine whether RASSF7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122526
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF4A is perturbed and the expression of MTURN is measured. Does this perturbation cause a significant change in MTURN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF4A is perturbed and the expression of MTURN is measured. Does this perturbation cause a significant change in MTURN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55080
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AP2M1 is perturbed and PPARD expression is observed. Does this perturbation lead to a significant difference in PPARD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AP2M1 is perturbed and PPARD expression is observed. Does this perturbation lead to a significant difference in PPARD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18313
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCAPD2 and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCAPD2 and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38704
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTB, does the expression profile of TPD52L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACTB, does the expression profile of TPD52L1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":267
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GFER, does the expression profile of MRAS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GFER, does the expression profile of MRAS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100477
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OGFOD1 and then measure expression of OTUD5. Does this perturbation cause a significant change in OTUD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OGFOD1 and then measure expression of OTUD5. Does this perturbation cause a significant change in OTUD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54784
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TPI1 and examine the expression of MORC3. Does perturbing TPI1 lead to a significant change in MORC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TPI1 and examine the expression of MORC3. Does perturbing TPI1 lead to a significant change in MORC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62761
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LTBP3 is associated with a significant change in FZD8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LTBP3 is associated with a significant change in FZD8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42955
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FAM207A is perturbed and CD58 expression is observed. Does this perturbation lead to a significant difference in CD58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FAM207A is perturbed and CD58 expression is observed. Does this perturbation lead to a significant difference in CD58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18083
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOC1 is associated with a significant change in POLR2M expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOC1 is associated with a significant change in POLR2M expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99995
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of YIPF4. Does this perturbation cause a significant change in YIPF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of YIPF4. Does this perturbation cause a significant change in YIPF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109054
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MMS19 is perturbed and FUNDC1 expression is observed. Does this perturbation lead to a significant difference in FUNDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MMS19 is perturbed and FUNDC1 expression is observed. Does this perturbation lead to a significant difference in FUNDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26323
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PNO1 and monitor GAS2L1 expression. Decide whether this perturbation leads to a significant alteration in GAS2L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PNO1 and monitor GAS2L1 expression. Decide whether this perturbation leads to a significant alteration in GAS2L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103828
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HUWE1 is perturbed and OPTN expression is quantified. Does this perturbation result in a significant change in OPTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HUWE1 is perturbed and OPTN expression is quantified. Does this perturbation result in a significant change in OPTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50272
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ADAM10 is perturbed and AC127502.2 expression is measured. Determine whether AC127502.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ADAM10 is perturbed and AC127502.2 expression is measured. Determine whether AC127502.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15589
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CYC1 is perturbed and ZDHHC3 expression is quantified. Does this perturbation result in a significant change in ZDHHC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CYC1 is perturbed and ZDHHC3 expression is quantified. Does this perturbation result in a significant change in ZDHHC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74602
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP9 and then measure expression of FLYWCH1. Does this perturbation cause a significant change in FLYWCH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP9 and then measure expression of FLYWCH1. Does this perturbation cause a significant change in FLYWCH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77474
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA8 and then measure expression of CNN2. Does this perturbation cause a significant change in CNN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFA8 and then measure expression of CNN2. Does this perturbation cause a significant change in CNN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88964
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COQ4 is associated with a significant change in MTA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COQ4 is associated with a significant change in MTA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119245
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRELID1 is perturbed and the expression of TPRA1 is measured. Does this perturbation cause a significant change in TPRA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRELID1 is perturbed and the expression of TPRA1 is measured. Does this perturbation cause a significant change in TPRA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60820
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NEDD1 and monitor LINC00467 expression. Decide whether this perturbation leads to a significant alteration in LINC00467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEDD1 and monitor LINC00467 expression. Decide whether this perturbation leads to a significant alteration in LINC00467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25628
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PNISR is perturbed and PRICKLE2 expression is observed. Does this perturbation lead to a significant difference in PRICKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PNISR is perturbed and PRICKLE2 expression is observed. Does this perturbation lead to a significant difference in PRICKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5933
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TRMT10C is perturbed and SERTAD1 expression is observed. Does this perturbation lead to a significant difference in SERTAD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TRMT10C is perturbed and SERTAD1 expression is observed. Does this perturbation lead to a significant difference in SERTAD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42333
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SIN3A, does the expression profile of CLN8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SIN3A, does the expression profile of CLN8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73087
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TWISTNB is perturbed and DAP expression is quantified. Does this perturbation result in a significant change in DAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TWISTNB is perturbed and DAP expression is quantified. Does this perturbation result in a significant change in DAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116752
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS18 is perturbed and FAP expression is measured. Determine whether FAP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS18 is perturbed and FAP expression is measured. Determine whether FAP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81549
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PREB is perturbed and UBXN6 expression is quantified. Does this perturbation result in a significant change in UBXN6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PREB is perturbed and UBXN6 expression is quantified. Does this perturbation result in a significant change in UBXN6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98412
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLD1 is perturbed and NSUN5 expression is quantified. Does this perturbation result in a significant change in NSUN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLD1 is perturbed and NSUN5 expression is quantified. Does this perturbation result in a significant change in NSUN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14682
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS10 is perturbed and the expression of BAG4 is measured. Determine whether BAG4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS10 is perturbed and the expression of BAG4 is measured. Determine whether BAG4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109906
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR77 and examine the expression of CCNG1. Does perturbing WDR77 lead to a significant change in CCNG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR77 and examine the expression of CCNG1. Does perturbing WDR77 lead to a significant change in CCNG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48401
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AAR2 is associated with a significant change in CRIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AAR2 is associated with a significant change in CRIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105955
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLTC is perturbed and GNPTAB expression is observed. Does this perturbation lead to a significant difference in GNPTAB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLTC is perturbed and GNPTAB expression is observed. Does this perturbation lead to a significant difference in GNPTAB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23373
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSE1L is perturbed and the expression of TCEA2 is measured. Determine whether TCEA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSE1L is perturbed and the expression of TCEA2 is measured. Determine whether TCEA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21616
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO7 is perturbed and BDNF expression is quantified. Does this perturbation result in a significant change in BDNF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO7 is perturbed and BDNF expression is quantified. Does this perturbation result in a significant change in BDNF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52362
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of OGFRL1. Does this perturbation cause a significant change in OGFRL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of OGFRL1. Does this perturbation cause a significant change in OGFRL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66214
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBA5 is perturbed and the expression of KPNA2 is measured. Does this perturbation cause a significant change in KPNA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBA5 is perturbed and the expression of KPNA2 is measured. Does this perturbation cause a significant change in KPNA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78810
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LAMTOR1 is perturbed and FNIP1 expression is measured. Determine whether FNIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LAMTOR1 is perturbed and FNIP1 expression is measured. Determine whether FNIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38189
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNOT3 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNOT3 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34226
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBM28 is perturbed and CCDC9B expression is observed. Does this perturbation lead to a significant difference in CCDC9B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBM28 is perturbed and CCDC9B expression is observed. Does this perturbation lead to a significant difference in CCDC9B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68413
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PFDN1 and monitor EVI5 expression. Decide whether this perturbation leads to a significant alteration in EVI5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PFDN1 and monitor EVI5 expression. Decide whether this perturbation leads to a significant alteration in EVI5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28148
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMA3 and then measure expression of RSF1. Does this perturbation cause a significant change in RSF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMA3 and then measure expression of RSF1. Does this perturbation cause a significant change in RSF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22884
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor OGT expression. Decide whether this perturbation leads to a significant alteration in OGT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor OGT expression. Decide whether this perturbation leads to a significant alteration in OGT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84358
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF7 is perturbed and the expression of NDUFB1 is measured. Does this perturbation cause a significant change in NDUFB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF7 is perturbed and the expression of NDUFB1 is measured. Does this perturbation cause a significant change in NDUFB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33860
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TOPBP1 is perturbed and the expression of HCG18 is measured. Does this perturbation cause a significant change in HCG18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TOPBP1 is perturbed and the expression of HCG18 is measured. Does this perturbation cause a significant change in HCG18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78550
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATF5 is perturbed and CAMK1D expression is observed. Does this perturbation lead to a significant difference in CAMK1D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATF5 is perturbed and CAMK1D expression is observed. Does this perturbation lead to a significant difference in CAMK1D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75373
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPZ and examine the expression of PYROXD2. Does perturbing CEBPZ lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPZ and examine the expression of PYROXD2. Does perturbing CEBPZ lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91051
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UPF2 is associated with a significant change in FAM214B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UPF2 is associated with a significant change in FAM214B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19165
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DBR1 is perturbed and TIMM10B expression is measured. Determine whether TIMM10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DBR1 is perturbed and TIMM10B expression is measured. Determine whether TIMM10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36799
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNASEH2C, does the expression profile of NAA16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNASEH2C, does the expression profile of NAA16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41667
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNRPD1 and monitor SPPL3 expression. Decide whether this perturbation leads to a significant alteration in SPPL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNRPD1 and monitor SPPL3 expression. Decide whether this perturbation leads to a significant alteration in SPPL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69938
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMB1 is perturbed and the expression of PITHD1 is measured. Determine whether PITHD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMB1 is perturbed and the expression of PITHD1 is measured. Determine whether PITHD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53496
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GUK1 is perturbed and the expression of UBL7 is measured. Determine whether UBL7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GUK1 is perturbed and the expression of UBL7 is measured. Determine whether UBL7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49656
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NSA2 is perturbed and HABP4 expression is measured. Determine whether HABP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NSA2 is perturbed and HABP4 expression is measured. Determine whether HABP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59449
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFAF7, does the expression profile of POLD4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFAF7, does the expression profile of POLD4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33897
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UCHL5 is perturbed and PICALM expression is measured. Determine whether PICALM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UCHL5 is perturbed and PICALM expression is measured. Determine whether PICALM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25579
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GTF2H1 is perturbed and the expression of RPS28 is measured. Does this perturbation cause a significant change in RPS28 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GTF2H1 is perturbed and the expression of RPS28 is measured. Does this perturbation cause a significant change in RPS28 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110720
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor TIMM22 expression. Decide whether this perturbation leads to a significant alteration in TIMM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor TIMM22 expression. Decide whether this perturbation leads to a significant alteration in TIMM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95278
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR5 is perturbed and CXorf40B expression is quantified. Does this perturbation result in a significant change in CXorf40B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR5 is perturbed and CXorf40B expression is quantified. Does this perturbation result in a significant change in CXorf40B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61002
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TOMM40 and monitor LPIN2 expression. Decide whether this perturbation leads to a significant alteration in LPIN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TOMM40 and monitor LPIN2 expression. Decide whether this perturbation leads to a significant alteration in LPIN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58458
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRNP27 is perturbed and the expression of RSRP1 is measured. Does this perturbation cause a significant change in RSRP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRNP27 is perturbed and the expression of RSRP1 is measured. Does this perturbation cause a significant change in RSRP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72190
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SART1 and then measure expression of ARNT. Does this perturbation cause a significant change in ARNT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SART1 and then measure expression of ARNT. Does this perturbation cause a significant change in ARNT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6654
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2H4 and examine the expression of TGFBR2. Does perturbing GTF2H4 lead to a significant change in TGFBR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF2H4 and examine the expression of TGFBR2. Does perturbing GTF2H4 lead to a significant change in TGFBR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61991
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS21 is perturbed and the expression of PPP2R3A is measured. Does this perturbation cause a significant change in PPP2R3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS21 is perturbed and the expression of PPP2R3A is measured. Does this perturbation cause a significant change in PPP2R3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13570
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PGD is perturbed and PSMD6 expression is observed. Does this perturbation lead to a significant difference in PSMD6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PGD is perturbed and PSMD6 expression is observed. Does this perturbation lead to a significant difference in PSMD6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8403
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD1 is perturbed and the expression of PLK3 is measured. Does this perturbation cause a significant change in PLK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD1 is perturbed and the expression of PLK3 is measured. Does this perturbation cause a significant change in PLK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96730
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNUPN is perturbed and the expression of RDH11 is measured. Does this perturbation cause a significant change in RDH11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNUPN is perturbed and the expression of RDH11 is measured. Does this perturbation cause a significant change in RDH11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38860
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GFOD2 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GFOD2 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6999
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IMPDH2 and examine the expression of ARID2. Does perturbing IMPDH2 lead to a significant change in ARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IMPDH2 and examine the expression of ARID2. Does perturbing IMPDH2 lead to a significant change in ARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10211
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRPF31 and monitor POLR2C expression. Decide whether this perturbation leads to a significant alteration in POLR2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRPF31 and monitor POLR2C expression. Decide whether this perturbation leads to a significant alteration in POLR2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25988
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POT1 and monitor TEX9 expression. Decide whether this perturbation leads to a significant alteration in TEX9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POT1 and monitor TEX9 expression. Decide whether this perturbation leads to a significant alteration in TEX9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116678
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ENY2 and examine the expression of DCP2. Does perturbing ENY2 lead to a significant change in DCP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ENY2 and examine the expression of DCP2. Does perturbing ENY2 lead to a significant change in DCP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75951
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL15 is associated with a significant change in PAM16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL15 is associated with a significant change in PAM16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53415
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3L is associated with a significant change in TMEM115 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF3L is associated with a significant change in TMEM115 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9385
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor PLXNA2 expression. Decide whether this perturbation leads to a significant alteration in PLXNA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor PLXNA2 expression. Decide whether this perturbation leads to a significant alteration in PLXNA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49808
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FTSJ3 is perturbed and ZNF587 expression is observed. Does this perturbation lead to a significant difference in ZNF587 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FTSJ3 is perturbed and ZNF587 expression is observed. Does this perturbation lead to a significant difference in ZNF587 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75203
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2M is perturbed and CENPL expression is measured. Determine whether CENPL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2M is perturbed and CENPL expression is measured. Determine whether CENPL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7729
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HDAC3 and monitor FAM171A1 expression. Decide whether this perturbation leads to a significant alteration in FAM171A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HDAC3 and monitor FAM171A1 expression. Decide whether this perturbation leads to a significant alteration in FAM171A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76248
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PAM16 is perturbed and LNPEP expression is quantified. Does this perturbation result in a significant change in LNPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PAM16 is perturbed and LNPEP expression is quantified. Does this perturbation result in a significant change in LNPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89552
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD8 is perturbed and the expression of ZNF407 is measured. Determine whether ZNF407 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD8 is perturbed and the expression of ZNF407 is measured. Determine whether ZNF407 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60336
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2G is associated with a significant change in SCNM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2G is associated with a significant change in SCNM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113705
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEN1 is perturbed and the expression of KCNN4 is measured. Does this perturbation cause a significant change in KCNN4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEN1 is perturbed and the expression of KCNN4 is measured. Does this perturbation cause a significant change in KCNN4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108900
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NAA38 is perturbed and NECTIN3 expression is observed. Does this perturbation lead to a significant difference in NECTIN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NAA38 is perturbed and NECTIN3 expression is observed. Does this perturbation lead to a significant difference in NECTIN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13033
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPS10 and monitor UQCRB expression. Decide whether this perturbation leads to a significant alteration in UQCRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPS10 and monitor UQCRB expression. Decide whether this perturbation leads to a significant alteration in UQCRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65368
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP14 and then measure expression of CNOT6L. Does this perturbation cause a significant change in CNOT6L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NOP14 and then measure expression of CNOT6L. Does this perturbation cause a significant change in CNOT6L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97774
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MMGT1 and monitor MTX3 expression. Decide whether this perturbation leads to a significant alteration in MTX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MMGT1 and monitor MTX3 expression. Decide whether this perturbation leads to a significant alteration in MTX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21738
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COX10 is perturbed and CEP55 expression is measured. Determine whether CEP55 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COX10 is perturbed and CEP55 expression is measured. Determine whether CEP55 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3019
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88427
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOLC1 is perturbed and PIK3R1 expression is observed. Does this perturbation lead to a significant difference in PIK3R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOLC1 is perturbed and PIK3R1 expression is observed. Does this perturbation lead to a significant difference in PIK3R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1333
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP6V0D1 and monitor LIPA expression. Decide whether this perturbation leads to a significant alteration in LIPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP6V0D1 and monitor LIPA expression. Decide whether this perturbation leads to a significant alteration in LIPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107528
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb WAC and monitor ABL1 expression. Decide whether this perturbation leads to a significant alteration in ABL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb WAC and monitor ABL1 expression. Decide whether this perturbation leads to a significant alteration in ABL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18798
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LRP5 is perturbed and FAM214B expression is quantified. Does this perturbation result in a significant change in FAM214B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LRP5 is perturbed and FAM214B expression is quantified. Does this perturbation result in a significant change in FAM214B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76982
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDC6 is perturbed and the expression of OPTN is measured. Determine whether OPTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDC6 is perturbed and the expression of OPTN is measured. Determine whether OPTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5666
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABHD17A is perturbed and the expression of TUBGCP4 is measured. Determine whether TUBGCP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ABHD17A is perturbed and the expression of TUBGCP4 is measured. Determine whether TUBGCP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71166
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOSC2 and examine the expression of ZNF197. Does perturbing EXOSC2 lead to a significant change in ZNF197 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOSC2 and examine the expression of ZNF197. Does perturbing EXOSC2 lead to a significant change in ZNF197 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104661
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPL is associated with a significant change in PDP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPL is associated with a significant change in PDP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24555
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb VEZT and monitor EFL1 expression. Decide whether this perturbation leads to a significant alteration in EFL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb VEZT and monitor EFL1 expression. Decide whether this perturbation leads to a significant alteration in EFL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67758
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CXXC1 and then measure expression of RRP12. Does this perturbation cause a significant change in RRP12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CXXC1 and then measure expression of RRP12. Does this perturbation cause a significant change in RRP12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67614
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HLA-C and examine the expression of SIPA1L1. Does perturbing HLA-C lead to a significant change in SIPA1L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HLA-C and examine the expression of SIPA1L1. Does perturbing HLA-C lead to a significant change in SIPA1L1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22411
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMB7 and examine the expression of RSF1. Does perturbing PSMB7 lead to a significant change in RSF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMB7 and examine the expression of RSF1. Does perturbing PSMB7 lead to a significant change in RSF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119801
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GAPDH and monitor SMIM10L1 expression. Decide whether this perturbation leads to a significant alteration in SMIM10L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GAPDH and monitor SMIM10L1 expression. Decide whether this perturbation leads to a significant alteration in SMIM10L1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54508
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC1A is perturbed and the expression of CLIP3 is measured. Determine whether CLIP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMC1A is perturbed and the expression of CLIP3 is measured. Determine whether CLIP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18346
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EXOSC3 and monitor MBD5 expression. Decide whether this perturbation leads to a significant alteration in MBD5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EXOSC3 and monitor MBD5 expression. Decide whether this perturbation leads to a significant alteration in MBD5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98358
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC10 is perturbed and STXBP1 expression is measured. Determine whether STXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC10 is perturbed and STXBP1 expression is measured. Determine whether STXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56579
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, THRAP3 is perturbed and the expression of GPAT3 is measured. Does this perturbation cause a significant change in GPAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, THRAP3 is perturbed and the expression of GPAT3 is measured. Does this perturbation cause a significant change in GPAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97390
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PIK3R4, does the expression profile of FAM149B1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PIK3R4, does the expression profile of FAM149B1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108207
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MYSM1 is perturbed and DDOST expression is observed. Does this perturbation lead to a significant difference in DDOST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MYSM1 is perturbed and DDOST expression is observed. Does this perturbation lead to a significant difference in DDOST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53663
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TCERG1 is perturbed and YIPF4 expression is observed. Does this perturbation lead to a significant difference in YIPF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TCERG1 is perturbed and YIPF4 expression is observed. Does this perturbation lead to a significant difference in YIPF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40183
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ALG13 is associated with a significant change in NIPA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ALG13 is associated with a significant change in NIPA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107435
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPP14 is perturbed and PLCB4 expression is quantified. Does this perturbation result in a significant change in PLCB4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPP14 is perturbed and PLCB4 expression is quantified. Does this perturbation result in a significant change in PLCB4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64132
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS is perturbed and CAMLG expression is measured. Determine whether CAMLG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS is perturbed and CAMLG expression is measured. Determine whether CAMLG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106919
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPS2 and then measure expression of AC027031.2. Does this perturbation cause a significant change in AC027031.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPS2 and then measure expression of AC027031.2. Does this perturbation cause a significant change in AC027031.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33414
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPS5 is perturbed and the expression of ATP2C1 is measured. Determine whether ATP2C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPS5 is perturbed and the expression of ATP2C1 is measured. Determine whether ATP2C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89066
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FASTKD5, does the expression profile of SSBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FASTKD5, does the expression profile of SSBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8297
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPAP2 is perturbed and the expression of LTBR is measured. Does this perturbation cause a significant change in LTBR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RPAP2 is perturbed and the expression of LTBR is measured. Does this perturbation cause a significant change in LTBR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24220
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPIL1 is perturbed and KMT2B expression is quantified. Does this perturbation result in a significant change in KMT2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPIL1 is perturbed and KMT2B expression is quantified. Does this perturbation result in a significant change in KMT2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33022
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGLN2 is associated with a significant change in MIR210HG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGLN2 is associated with a significant change in MIR210HG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20615
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ANAPC11 and monitor NFKBIB expression. Decide whether this perturbation leads to a significant alteration in NFKBIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ANAPC11 and monitor NFKBIB expression. Decide whether this perturbation leads to a significant alteration in NFKBIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76828
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DYNC1H1 is perturbed and MAST4 expression is quantified. Does this perturbation result in a significant change in MAST4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DYNC1H1 is perturbed and MAST4 expression is quantified. Does this perturbation result in a significant change in MAST4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98462
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RNASEH2C and monitor TUBA4A expression. Decide whether this perturbation leads to a significant alteration in TUBA4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RNASEH2C and monitor TUBA4A expression. Decide whether this perturbation leads to a significant alteration in TUBA4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41628
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BRD8 is perturbed and FBXO32 expression is observed. Does this perturbation lead to a significant difference in FBXO32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BRD8 is perturbed and FBXO32 expression is observed. Does this perturbation lead to a significant difference in FBXO32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93913
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEN1 is perturbed and CYP1B1 expression is quantified. Does this perturbation result in a significant change in CYP1B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEN1 is perturbed and CYP1B1 expression is quantified. Does this perturbation result in a significant change in CYP1B1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108892
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEPHS2 is perturbed and DHDDS expression is measured. Determine whether DHDDS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEPHS2 is perturbed and DHDDS expression is measured. Determine whether DHDDS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104909
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of RNF5. Does this perturbation cause a significant change in RNF5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of RNF5. Does this perturbation cause a significant change in RNF5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11514
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOC4L is perturbed and CELF1 expression is observed. Does this perturbation lead to a significant difference in CELF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOC4L is perturbed and CELF1 expression is observed. Does this perturbation lead to a significant difference in CELF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78153
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UHRF1 is perturbed and ESCO1 expression is measured. Determine whether ESCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UHRF1 is perturbed and ESCO1 expression is measured. Determine whether ESCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66789
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCBP2 is perturbed and the expression of IL7R is measured. Determine whether IL7R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCBP2 is perturbed and the expression of IL7R is measured. Determine whether IL7R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12746
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in SEC24D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in SEC24D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61395
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL41 and examine the expression of ACO1. Does perturbing RPL41 lead to a significant change in ACO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL41 and examine the expression of ACO1. Does perturbing RPL41 lead to a significant change in ACO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22621
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PIK3C3 is perturbed and the expression of DYNLRB1 is measured. Does this perturbation cause a significant change in DYNLRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PIK3C3 is perturbed and the expression of DYNLRB1 is measured. Does this perturbation cause a significant change in DYNLRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76290
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HUS1 is perturbed and FAM120A expression is measured. Determine whether FAM120A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HUS1 is perturbed and FAM120A expression is measured. Determine whether FAM120A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2709
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUVBL2 and then measure expression of COPE. Does this perturbation cause a significant change in COPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUVBL2 and then measure expression of COPE. Does this perturbation cause a significant change in COPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1644
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DIS3 is perturbed and the expression of PSEN1 is measured. Does this perturbation cause a significant change in PSEN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DIS3 is perturbed and the expression of PSEN1 is measured. Does this perturbation cause a significant change in PSEN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96860
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNC, does the expression profile of DNAJC17 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNC, does the expression profile of DNAJC17 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81967
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ESYT1 is associated with a significant change in BLOC1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ESYT1 is associated with a significant change in BLOC1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88245
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPP1R10 and monitor SMG1 expression. Decide whether this perturbation leads to a significant alteration in SMG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPP1R10 and monitor SMG1 expression. Decide whether this perturbation leads to a significant alteration in SMG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52248
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb INTS1 and monitor RASSF8 expression. Decide whether this perturbation leads to a significant alteration in RASSF8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb INTS1 and monitor RASSF8 expression. Decide whether this perturbation leads to a significant alteration in RASSF8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44228
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CPSF6 is perturbed and the expression of NFAT5 is measured. Does this perturbation cause a significant change in NFAT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CPSF6 is perturbed and the expression of NFAT5 is measured. Does this perturbation cause a significant change in NFAT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61070
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of RINT1 is measured. Does this perturbation cause a significant change in RINT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of RINT1 is measured. Does this perturbation cause a significant change in RINT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99390
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OXA1L is perturbed and the expression of SLC37A4 is measured. Determine whether SLC37A4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OXA1L is perturbed and the expression of SLC37A4 is measured. Determine whether SLC37A4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72756
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANAPC10 is associated with a significant change in TIMM8B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANAPC10 is associated with a significant change in TIMM8B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57285
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2K and examine the expression of VAMP2. Does perturbing POLR2K lead to a significant change in VAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR2K and examine the expression of VAMP2. Does perturbing POLR2K lead to a significant change in VAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5851
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TOR2A is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TOR2A is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81070
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NLE1 is perturbed and the expression of D2HGDH is measured. Determine whether D2HGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NLE1 is perturbed and the expression of D2HGDH is measured. Determine whether D2HGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71246
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCT8 is perturbed and CACNA2D1 expression is observed. Does this perturbation lead to a significant difference in CACNA2D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCT8 is perturbed and CACNA2D1 expression is observed. Does this perturbation lead to a significant difference in CACNA2D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92283
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHCHD2 is perturbed and UBE2F expression is measured. Determine whether UBE2F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHCHD2 is perturbed and UBE2F expression is measured. Determine whether UBE2F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77089
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MVD, does the expression profile of IFT88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MVD, does the expression profile of IFT88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67447
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DHX36 and monitor NELFB expression. Decide whether this perturbation leads to a significant alteration in NELFB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DHX36 and monitor NELFB expression. Decide whether this perturbation leads to a significant alteration in NELFB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71438
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NASP is perturbed and the expression of YPEL5 is measured. Determine whether YPEL5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NASP is perturbed and the expression of YPEL5 is measured. Determine whether YPEL5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11626
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTK2 and then measure expression of USE1. Does this perturbation cause a significant change in USE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTK2 and then measure expression of USE1. Does this perturbation cause a significant change in USE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11324
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTBP3 and examine the expression of SNHG19. Does perturbing LTBP3 lead to a significant change in SNHG19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTBP3 and examine the expression of SNHG19. Does perturbing LTBP3 lead to a significant change in SNHG19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42981
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of SMIM12 is measured. Determine whether SMIM12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM8 is perturbed and the expression of SMIM12 is measured. Determine whether SMIM12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118936
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PALB2 and monitor PLPPR2 expression. Decide whether this perturbation leads to a significant alteration in PLPPR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PALB2 and monitor PLPPR2 expression. Decide whether this perturbation leads to a significant alteration in PLPPR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30938
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and NUCB2 expression is observed. Does this perturbation lead to a significant difference in NUCB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and NUCB2 expression is observed. Does this perturbation lead to a significant difference in NUCB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69783
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TXNL4B and then measure expression of FDXR. Does this perturbation cause a significant change in FDXR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TXNL4B and then measure expression of FDXR. Does this perturbation cause a significant change in FDXR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26104
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDRG1 is associated with a significant change in WHAMM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDRG1 is associated with a significant change in WHAMM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65445
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX19A is perturbed and BET1L expression is quantified. Does this perturbation result in a significant change in BET1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX19A is perturbed and BET1L expression is quantified. Does this perturbation result in a significant change in BET1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24952
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of H2AFZ is associated with a significant change in SCAF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of H2AFZ is associated with a significant change in SCAF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70475
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARPC2 is perturbed and ITGA11 expression is observed. Does this perturbation lead to a significant difference in ITGA11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARPC2 is perturbed and ITGA11 expression is observed. Does this perturbation lead to a significant difference in ITGA11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52963
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HIRA is perturbed and the expression of GABARAPL1 is measured. Does this perturbation cause a significant change in GABARAPL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HIRA is perturbed and the expression of GABARAPL1 is measured. Does this perturbation cause a significant change in GABARAPL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50330
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NMD3 is perturbed and TXNDC9 expression is measured. Determine whether TXNDC9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NMD3 is perturbed and TXNDC9 expression is measured. Determine whether TXNDC9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93639
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS7 is perturbed and the expression of LGALS8 is measured. Does this perturbation cause a significant change in LGALS8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS7 is perturbed and the expression of LGALS8 is measured. Does this perturbation cause a significant change in LGALS8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82570
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZWINT and monitor POMGNT1 expression. Decide whether this perturbation leads to a significant alteration in POMGNT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZWINT and monitor POMGNT1 expression. Decide whether this perturbation leads to a significant alteration in POMGNT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48958
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COA5 is perturbed and the expression of JUP is measured. Determine whether JUP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COA5 is perturbed and the expression of JUP is measured. Determine whether JUP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84506
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF23 and examine the expression of FAM234A. Does perturbing KIF23 lead to a significant change in FAM234A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF23 and examine the expression of FAM234A. Does perturbing KIF23 lead to a significant change in FAM234A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104691
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBC1D1 is perturbed and CYB5R1 expression is observed. Does this perturbation lead to a significant difference in CYB5R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBC1D1 is perturbed and CYB5R1 expression is observed. Does this perturbation lead to a significant difference in CYB5R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96553
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS26 is perturbed and the expression of TUBA1B is measured. Determine whether TUBA1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS26 is perturbed and the expression of TUBA1B is measured. Determine whether TUBA1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72626
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMC4 is perturbed and CHP1 expression is observed. Does this perturbation lead to a significant difference in CHP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SMC4 is perturbed and CHP1 expression is observed. Does this perturbation lead to a significant difference in CHP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25413
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP98 is associated with a significant change in SLC44A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP98 is associated with a significant change in SLC44A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27225
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBA3 is perturbed and GPATCH8 expression is quantified. Does this perturbation result in a significant change in GPATCH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBA3 is perturbed and GPATCH8 expression is quantified. Does this perturbation result in a significant change in GPATCH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39892
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUDS3, does the expression profile of ABI1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUDS3, does the expression profile of ABI1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57457
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRA1 is perturbed and GID4 expression is measured. Determine whether GID4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRA1 is perturbed and GID4 expression is measured. Determine whether GID4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17709
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NAA10 is perturbed and the expression of TMED7 is measured. Determine whether TMED7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NAA10 is perturbed and the expression of TMED7 is measured. Determine whether TMED7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63006
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELP5 is perturbed and RPL37A expression is quantified. Does this perturbation result in a significant change in RPL37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELP5 is perturbed and RPL37A expression is quantified. Does this perturbation result in a significant change in RPL37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41542
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPE is perturbed and STX5 expression is measured. Determine whether STX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPE is perturbed and STX5 expression is measured. Determine whether STX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46789
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FNBP4 is perturbed and the expression of ZNF395 is measured. Determine whether ZNF395 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FNBP4 is perturbed and the expression of ZNF395 is measured. Determine whether ZNF395 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41826
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCR is perturbed and the expression of TIMM29 is measured. Does this perturbation cause a significant change in TIMM29 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCR is perturbed and the expression of TIMM29 is measured. Does this perturbation cause a significant change in TIMM29 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22860
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TRRAP is perturbed and LTBP3 expression is observed. Does this perturbation lead to a significant difference in LTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TRRAP is perturbed and LTBP3 expression is observed. Does this perturbation lead to a significant difference in LTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109913
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SMC3 is perturbed and the expression of VAMP4 is measured. Does this perturbation cause a significant change in VAMP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SMC3 is perturbed and the expression of VAMP4 is measured. Does this perturbation cause a significant change in VAMP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95100
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERCC2 is associated with a significant change in COL4A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ERCC2 is associated with a significant change in COL4A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74405
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EFR3A is perturbed and the expression of MLST8 is measured. Does this perturbation cause a significant change in MLST8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EFR3A is perturbed and the expression of MLST8 is measured. Does this perturbation cause a significant change in MLST8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47240
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COQ5 is perturbed and the expression of ATG16L1 is measured. Determine whether ATG16L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COQ5 is perturbed and the expression of ATG16L1 is measured. Determine whether ATG16L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40846
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMA2 and examine the expression of KIAA1217. Does perturbing PSMA2 lead to a significant change in KIAA1217 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMA2 and examine the expression of KIAA1217. Does perturbing PSMA2 lead to a significant change in KIAA1217 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115381
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EXOC5 is perturbed and the expression of BAZ2B is measured. Does this perturbation cause a significant change in BAZ2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EXOC5 is perturbed and the expression of BAZ2B is measured. Does this perturbation cause a significant change in BAZ2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102490
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPRD1B is perturbed and the expression of PEX13 is measured. Determine whether PEX13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPRD1B is perturbed and the expression of PEX13 is measured. Determine whether PEX13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82226
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR55 and examine the expression of RTL8C. Does perturbing WDR55 lead to a significant change in RTL8C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR55 and examine the expression of RTL8C. Does perturbing WDR55 lead to a significant change in RTL8C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122571
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NAA25 is perturbed and the expression of CCDC186 is measured. Determine whether CCDC186 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NAA25 is perturbed and the expression of CCDC186 is measured. Determine whether CCDC186 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53886
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NSMCE2, does the expression profile of MAGED2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NSMCE2, does the expression profile of MAGED2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45937
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POGZ and monitor CYSTM1 expression. Decide whether this perturbation leads to a significant alteration in CYSTM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POGZ and monitor CYSTM1 expression. Decide whether this perturbation leads to a significant alteration in CYSTM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62318
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD4 is perturbed and TAZ expression is quantified. Does this perturbation result in a significant change in TAZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPUSD4 is perturbed and TAZ expression is quantified. Does this perturbation result in a significant change in TAZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61252
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAK1IP1 is associated with a significant change in SMG9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PAK1IP1 is associated with a significant change in SMG9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71365
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS28 is perturbed and RTN4 expression is measured. Determine whether RTN4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPS28 is perturbed and RTN4 expression is measured. Determine whether RTN4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122789
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GABPA is perturbed and ZBTB11 expression is quantified. Does this perturbation result in a significant change in ZBTB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GABPA is perturbed and ZBTB11 expression is quantified. Does this perturbation result in a significant change in ZBTB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75652
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUB1 is perturbed and TOGARAM1 expression is quantified. Does this perturbation result in a significant change in TOGARAM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUB1 is perturbed and TOGARAM1 expression is quantified. Does this perturbation result in a significant change in TOGARAM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78392
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHTF18 is perturbed and the expression of MSRB1 is measured. Does this perturbation cause a significant change in MSRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHTF18 is perturbed and the expression of MSRB1 is measured. Does this perturbation cause a significant change in MSRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71930
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARL4D and then measure expression of PGAM5. Does this perturbation cause a significant change in PGAM5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARL4D and then measure expression of PGAM5. Does this perturbation cause a significant change in PGAM5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78244
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP98, does the expression profile of SLC44A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP98, does the expression profile of SLC44A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27227
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DR1 is perturbed and FN1 expression is observed. Does this perturbation lead to a significant difference in FN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DR1 is perturbed and FN1 expression is observed. Does this perturbation lead to a significant difference in FN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121353
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of ZNF430. Does this perturbation cause a significant change in ZNF430 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SETDB1 and then measure expression of ZNF430. Does this perturbation cause a significant change in ZNF430 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95024
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP14 is perturbed and the expression of KDM4B is measured. Does this perturbation cause a significant change in KDM4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP14 is perturbed and the expression of KDM4B is measured. Does this perturbation cause a significant change in KDM4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97750
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NSA2 is perturbed and the expression of SERPINB2 is measured. Does this perturbation cause a significant change in SERPINB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NSA2 is perturbed and the expression of SERPINB2 is measured. Does this perturbation cause a significant change in SERPINB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59390
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NASP is perturbed and the expression of YPEL5 is measured. Does this perturbation cause a significant change in YPEL5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NASP is perturbed and the expression of YPEL5 is measured. Does this perturbation cause a significant change in YPEL5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11620
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFS5 is perturbed and the expression of ATP6V1A is measured. Determine whether ATP6V1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFS5 is perturbed and the expression of ATP6V1A is measured. Determine whether ATP6V1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2246
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHTOP is perturbed and the expression of ACYP1 is measured. Determine whether ACYP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHTOP is perturbed and the expression of ACYP1 is measured. Determine whether ACYP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23076
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DPH3 and monitor RP9 expression. Decide whether this perturbation leads to a significant alteration in RP9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DPH3 and monitor RP9 expression. Decide whether this perturbation leads to a significant alteration in RP9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46768
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPRD1B is perturbed and FBXW7 expression is quantified. Does this perturbation result in a significant change in FBXW7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPRD1B is perturbed and FBXW7 expression is quantified. Does this perturbation result in a significant change in FBXW7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82232
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHTF18 is perturbed and the expression of NDST1 is measured. Does this perturbation cause a significant change in NDST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHTF18 is perturbed and the expression of NDST1 is measured. Does this perturbation cause a significant change in NDST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71950
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC16 is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC16 is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25265
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATF4 is perturbed and KRI1 expression is observed. Does this perturbation lead to a significant difference in KRI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATF4 is perturbed and KRI1 expression is observed. Does this perturbation lead to a significant difference in KRI1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38403
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZCRB1 is perturbed and the expression of GREM1 is measured. Does this perturbation cause a significant change in GREM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZCRB1 is perturbed and the expression of GREM1 is measured. Does this perturbation cause a significant change in GREM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70090
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAPC2 and monitor C9orf85 expression. Decide whether this perturbation leads to a significant alteration in C9orf85 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAPC2 and monitor C9orf85 expression. Decide whether this perturbation leads to a significant alteration in C9orf85 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84908
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YY1 and examine the expression of MSRA. Does perturbing YY1 lead to a significant change in MSRA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YY1 and examine the expression of MSRA. Does perturbing YY1 lead to a significant change in MSRA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60281
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF3C1 and examine the expression of MOB2. Does perturbing GTF3C1 lead to a significant change in MOB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GTF3C1 and examine the expression of MOB2. Does perturbing GTF3C1 lead to a significant change in MOB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13371
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL6 and then measure expression of VOPP1. Does this perturbation cause a significant change in VOPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL6 and then measure expression of VOPP1. Does this perturbation cause a significant change in VOPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58634
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SMG8 and monitor CDS2 expression. Decide whether this perturbation leads to a significant alteration in CDS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SMG8 and monitor CDS2 expression. Decide whether this perturbation leads to a significant alteration in CDS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55348
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS21 is perturbed and FBXL15 expression is quantified. Does this perturbation result in a significant change in FBXL15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS21 is perturbed and FBXL15 expression is quantified. Does this perturbation result in a significant change in FBXL15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77642
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPIL1 is perturbed and the expression of COMMD9 is measured. Does this perturbation cause a significant change in COMMD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPIL1 is perturbed and the expression of COMMD9 is measured. Does this perturbation cause a significant change in COMMD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33040
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDK12 is perturbed and AK2 expression is quantified. Does this perturbation result in a significant change in AK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDK12 is perturbed and AK2 expression is quantified. Does this perturbation result in a significant change in AK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103052
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCT4 is perturbed and SGK1 expression is observed. Does this perturbation lead to a significant difference in SGK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCT4 is perturbed and SGK1 expression is observed. Does this perturbation lead to a significant difference in SGK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44483
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SDHD is associated with a significant change in RAB27B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SDHD is associated with a significant change in RAB27B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112045
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNIP1 is perturbed and the expression of MED10 is measured. Does this perturbation cause a significant change in MED10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNIP1 is perturbed and the expression of MED10 is measured. Does this perturbation cause a significant change in MED10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70630
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPW is associated with a significant change in FBXO32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CENPW is associated with a significant change in FBXO32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19395
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CTU2 and monitor SP2 expression. Decide whether this perturbation leads to a significant alteration in SP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CTU2 and monitor SP2 expression. Decide whether this perturbation leads to a significant alteration in SP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93818
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNB1, does the expression profile of ZNF576 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCNB1, does the expression profile of ZNF576 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73937
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDR39U1 is perturbed and GBE1 expression is observed. Does this perturbation lead to a significant difference in GBE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDR39U1 is perturbed and GBE1 expression is observed. Does this perturbation lead to a significant difference in GBE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70933
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LRR1 is perturbed and the expression of MIR31HG is measured. Does this perturbation cause a significant change in MIR31HG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LRR1 is perturbed and the expression of MIR31HG is measured. Does this perturbation cause a significant change in MIR31HG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102220
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PNO1 and then measure expression of ZFYVE21. Does this perturbation cause a significant change in ZFYVE21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PNO1 and then measure expression of ZFYVE21. Does this perturbation cause a significant change in ZFYVE21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103814
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC10 and then measure expression of STXBP1. Does this perturbation cause a significant change in STXBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC10 and then measure expression of STXBP1. Does this perturbation cause a significant change in STXBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56574
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF787 and then measure expression of PRKX. Does this perturbation cause a significant change in PRKX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF787 and then measure expression of PRKX. Does this perturbation cause a significant change in PRKX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102304
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BUD13 is perturbed and the expression of DDB2 is measured. Does this perturbation cause a significant change in DDB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BUD13 is perturbed and the expression of DDB2 is measured. Does this perturbation cause a significant change in DDB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110060
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD2 and examine the expression of HIBADH. Does perturbing CHCHD2 lead to a significant change in HIBADH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD2 and examine the expression of HIBADH. Does perturbing CHCHD2 lead to a significant change in HIBADH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77031
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SFPQ is perturbed and the expression of DMKN is measured. Does this perturbation cause a significant change in DMKN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SFPQ is perturbed and the expression of DMKN is measured. Does this perturbation cause a significant change in DMKN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58090
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAMM41, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TAMM41, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95697
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DTYMK and monitor LYSMD3 expression. Decide whether this perturbation leads to a significant alteration in LYSMD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DTYMK and monitor LYSMD3 expression. Decide whether this perturbation leads to a significant alteration in LYSMD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3658
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBE2I is perturbed and ERV3-1 expression is observed. Does this perturbation lead to a significant difference in ERV3-1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBE2I is perturbed and ERV3-1 expression is observed. Does this perturbation lead to a significant difference in ERV3-1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77713
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX11 and examine the expression of ZNF668. Does perturbing DDX11 lead to a significant change in ZNF668 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX11 and examine the expression of ZNF668. Does perturbing DDX11 lead to a significant change in ZNF668 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95071
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GSK3B is perturbed and ARAF expression is quantified. Does this perturbation result in a significant change in ARAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GSK3B is perturbed and ARAF expression is quantified. Does this perturbation result in a significant change in ARAF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38502
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TUBE1 and monitor TOLLIP expression. Decide whether this perturbation leads to a significant alteration in TOLLIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TUBE1 and monitor TOLLIP expression. Decide whether this perturbation leads to a significant alteration in TOLLIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38348
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YBX1, does the expression profile of XPO7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YBX1, does the expression profile of XPO7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43087
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2A, does the expression profile of USP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2A, does the expression profile of USP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106487
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRBD1 and then measure expression of KIAA0100. Does this perturbation cause a significant change in KIAA0100 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRBD1 and then measure expression of KIAA0100. Does this perturbation cause a significant change in KIAA0100 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91984
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB2 and then measure expression of STIP1. Does this perturbation cause a significant change in STIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMB2 and then measure expression of STIP1. Does this perturbation cause a significant change in STIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17954
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of MTHFS is measured. Does this perturbation cause a significant change in MTHFS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TRNP1 is perturbed and the expression of MTHFS is measured. Does this perturbation cause a significant change in MTHFS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99300
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP3 is perturbed and CLN8 expression is quantified. Does this perturbation result in a significant change in CLN8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP3 is perturbed and CLN8 expression is quantified. Does this perturbation result in a significant change in CLN8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97132
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM242 and examine the expression of DDIT4. Does perturbing TMEM242 lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM242 and examine the expression of DDIT4. Does perturbing TMEM242 lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5471
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BARD1 is perturbed and the expression of SPSB2 is measured. Does this perturbation cause a significant change in SPSB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BARD1 is perturbed and the expression of SPSB2 is measured. Does this perturbation cause a significant change in SPSB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122840
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBA1C is perturbed and the expression of KMT5B is measured. Determine whether KMT5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBA1C is perturbed and the expression of KMT5B is measured. Determine whether KMT5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85856
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GFOD2 is perturbed and the expression of TRAK1 is measured. Determine whether TRAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GFOD2 is perturbed and the expression of TRAK1 is measured. Determine whether TRAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7016
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SDE2 and then measure expression of ZMAT2. Does this perturbation cause a significant change in ZMAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SDE2 and then measure expression of ZMAT2. Does this perturbation cause a significant change in ZMAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115904
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HMGA1 is associated with a significant change in CHD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HMGA1 is associated with a significant change in CHD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8055
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPA is perturbed and the expression of ZNF672 is measured. Does this perturbation cause a significant change in ZNF672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPA is perturbed and the expression of ZNF672 is measured. Does this perturbation cause a significant change in ZNF672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58560
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2R1A and then measure expression of AC092807.3. Does this perturbation cause a significant change in AC092807.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2R1A and then measure expression of AC092807.3. Does this perturbation cause a significant change in AC092807.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72784
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PHF5A and examine the expression of SRSF10. Does perturbing PHF5A lead to a significant change in SRSF10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PHF5A and examine the expression of SRSF10. Does perturbing PHF5A lead to a significant change in SRSF10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99031
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD17A and examine the expression of DTNBP1. Does perturbing ABHD17A lead to a significant change in DTNBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABHD17A and examine the expression of DTNBP1. Does perturbing ABHD17A lead to a significant change in DTNBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71201
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ILF3, does the expression profile of RITA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ILF3, does the expression profile of RITA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72877
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCLAF1 is perturbed and the expression of ZDHHC16 is measured. Determine whether ZDHHC16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCLAF1 is perturbed and the expression of ZDHHC16 is measured. Determine whether ZDHHC16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108886
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRNP27 is perturbed and PRDX2 expression is observed. Does this perturbation lead to a significant difference in PRDX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNRNP27 is perturbed and PRDX2 expression is observed. Does this perturbation lead to a significant difference in PRDX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72223
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPH6 is perturbed and PIP4P1 expression is quantified. Does this perturbation result in a significant change in PIP4P1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DPH6 is perturbed and PIP4P1 expression is quantified. Does this perturbation result in a significant change in PIP4P1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54742
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASF1B and examine the expression of PDPR. Does perturbing ASF1B lead to a significant change in PDPR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASF1B and examine the expression of PDPR. Does perturbing ASF1B lead to a significant change in PDPR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85381
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RSRC2 and monitor PAK4 expression. Decide whether this perturbation leads to a significant alteration in PAK4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RSRC2 and monitor PAK4 expression. Decide whether this perturbation leads to a significant alteration in PAK4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11408
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MMS22L is perturbed and the expression of PLPPR2 is measured. Determine whether PLPPR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MMS22L is perturbed and the expression of PLPPR2 is measured. Determine whether PLPPR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81476
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD1 and examine the expression of EXOSC10. Does perturbing CHCHD1 lead to a significant change in EXOSC10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHCHD1 and examine the expression of EXOSC10. Does perturbing CHCHD1 lead to a significant change in EXOSC10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33921
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RNF113A is perturbed and SLU7 expression is observed. Does this perturbation lead to a significant difference in SLU7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RNF113A is perturbed and SLU7 expression is observed. Does this perturbation lead to a significant difference in SLU7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28353
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL23 is perturbed and FAM171B expression is measured. Determine whether FAM171B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL23 is perturbed and FAM171B expression is measured. Determine whether FAM171B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66599
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPRC1, does the expression profile of SPP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPRC1, does the expression profile of SPP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99647
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFB6 and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFB6 and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65924
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCAPD2 is perturbed and DYSF expression is observed. Does this perturbation lead to a significant difference in DYSF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCAPD2 is perturbed and DYSF expression is observed. Does this perturbation lead to a significant difference in DYSF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38713
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC4 and examine the expression of NORAD. Does perturbing TRAPPC4 lead to a significant change in NORAD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRAPPC4 and examine the expression of NORAD. Does perturbing TRAPPC4 lead to a significant change in NORAD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79871
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MFAP1 is perturbed and SPATA7 expression is quantified. Does this perturbation result in a significant change in SPATA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MFAP1 is perturbed and SPATA7 expression is quantified. Does this perturbation result in a significant change in SPATA7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9542
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPU is associated with a significant change in MFAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNRNPU is associated with a significant change in MFAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105075
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TSFM and monitor DHODH expression. Decide whether this perturbation leads to a significant alteration in DHODH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TSFM and monitor DHODH expression. Decide whether this perturbation leads to a significant alteration in DHODH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52538
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COG6 and examine the expression of PBX1. Does perturbing COG6 lead to a significant change in PBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COG6 and examine the expression of PBX1. Does perturbing COG6 lead to a significant change in PBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25731
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in ARHGEF28 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in ARHGEF28 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122745
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2Z and examine the expression of RXRB. Does perturbing UBE2Z lead to a significant change in RXRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBE2Z and examine the expression of RXRB. Does perturbing UBE2Z lead to a significant change in RXRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61441
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCAR1 is perturbed and STK38L expression is observed. Does this perturbation lead to a significant difference in STK38L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCAR1 is perturbed and STK38L expression is observed. Does this perturbation lead to a significant difference in STK38L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13833
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COASY is perturbed and the expression of MCTP1 is measured. Does this perturbation cause a significant change in MCTP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COASY is perturbed and the expression of MCTP1 is measured. Does this perturbation cause a significant change in MCTP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47620
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FAF2 and monitor SEC23IP expression. Decide whether this perturbation leads to a significant alteration in SEC23IP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FAF2 and monitor SEC23IP expression. Decide whether this perturbation leads to a significant alteration in SEC23IP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43038
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GOSR2 and examine the expression of CCDC22. Does perturbing GOSR2 lead to a significant change in CCDC22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GOSR2 and examine the expression of CCDC22. Does perturbing GOSR2 lead to a significant change in CCDC22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47531
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDHC is perturbed and ANKIB1 expression is observed. Does this perturbation lead to a significant difference in ANKIB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDHC is perturbed and ANKIB1 expression is observed. Does this perturbation lead to a significant difference in ANKIB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119353
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF207 is perturbed and TSLP expression is observed. Does this perturbation lead to a significant difference in TSLP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF207 is perturbed and TSLP expression is observed. Does this perturbation lead to a significant difference in TSLP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29733
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RGP1 and monitor MPC1 expression. Decide whether this perturbation leads to a significant alteration in MPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RGP1 and monitor MPC1 expression. Decide whether this perturbation leads to a significant alteration in MPC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80648
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP11B is perturbed and the expression of PMEPA1 is measured. Does this perturbation cause a significant change in PMEPA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP11B is perturbed and the expression of PMEPA1 is measured. Does this perturbation cause a significant change in PMEPA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89220
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIS18BP1 is perturbed and TXNRD2 expression is observed. Does this perturbation lead to a significant difference in TXNRD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIS18BP1 is perturbed and TXNRD2 expression is observed. Does this perturbation lead to a significant difference in TXNRD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82893
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USP37 and then measure expression of MARF1. Does this perturbation cause a significant change in MARF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to USP37 and then measure expression of MARF1. Does this perturbation cause a significant change in MARF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98604
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DYNLL2 is perturbed and CDC25B expression is observed. Does this perturbation lead to a significant difference in CDC25B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DYNLL2 is perturbed and CDC25B expression is observed. Does this perturbation lead to a significant difference in CDC25B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69233
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDHA is perturbed and CDCA7L expression is observed. Does this perturbation lead to a significant difference in CDCA7L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDHA is perturbed and CDCA7L expression is observed. Does this perturbation lead to a significant difference in CDCA7L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28833
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOL12, does the expression profile of DCTN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOL12, does the expression profile of DCTN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119497
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5F1B and examine the expression of UTP25. Does perturbing ATP5F1B lead to a significant change in UTP25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5F1B and examine the expression of UTP25. Does perturbing ATP5F1B lead to a significant change in UTP25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49941
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPC25 and monitor STK19 expression. Decide whether this perturbation leads to a significant alteration in STK19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPC25 and monitor STK19 expression. Decide whether this perturbation leads to a significant alteration in STK19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56598
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBX1 and monitor ZBTB44 expression. Decide whether this perturbation leads to a significant alteration in ZBTB44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBX1 and monitor ZBTB44 expression. Decide whether this perturbation leads to a significant alteration in ZBTB44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90788
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RAD51C and monitor MED13L expression. Decide whether this perturbation leads to a significant alteration in MED13L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RAD51C and monitor MED13L expression. Decide whether this perturbation leads to a significant alteration in MED13L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105488
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TEN1 is associated with a significant change in RNF40 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TEN1 is associated with a significant change in RNF40 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70295
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTC1, does the expression profile of RARRES1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTC1, does the expression profile of RARRES1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38027
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor LYPLAL1 expression. Decide whether this perturbation leads to a significant alteration in LYPLAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor LYPLAL1 expression. Decide whether this perturbation leads to a significant alteration in LYPLAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84398
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC7A6OS and examine the expression of FBN2. Does perturbing SLC7A6OS lead to a significant change in FBN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC7A6OS and examine the expression of FBN2. Does perturbing SLC7A6OS lead to a significant change in FBN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31061
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb METTL1 and monitor NCKAP5L expression. Decide whether this perturbation leads to a significant alteration in NCKAP5L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb METTL1 and monitor NCKAP5L expression. Decide whether this perturbation leads to a significant alteration in NCKAP5L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":468
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COG1 and then measure expression of ZNF512B. Does this perturbation cause a significant change in ZNF512B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COG1 and then measure expression of ZNF512B. Does this perturbation cause a significant change in ZNF512B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67594
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRPF19 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRPF19 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101423
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDFY3 is perturbed and APOOL expression is measured. Determine whether APOOL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDFY3 is perturbed and APOOL expression is measured. Determine whether APOOL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87219
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGAM5, does the expression profile of KDM3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGAM5, does the expression profile of KDM3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1217
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SART1 is perturbed and the expression of GTF2IRD1 is measured. Determine whether GTF2IRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SART1 is perturbed and the expression of GTF2IRD1 is measured. Determine whether GTF2IRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6646
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELOB is perturbed and the expression of ZSCAN30 is measured. Determine whether ZSCAN30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELOB is perturbed and the expression of ZSCAN30 is measured. Determine whether ZSCAN30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11276
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in SLFN5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in SLFN5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61405
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GINS4 is perturbed and MAU2 expression is observed. Does this perturbation lead to a significant difference in MAU2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GINS4 is perturbed and MAU2 expression is observed. Does this perturbation lead to a significant difference in MAU2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37383
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BOP1, does the expression profile of TPRG1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BOP1, does the expression profile of TPRG1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12047
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SBDS is perturbed and the expression of RRP36 is measured. Does this perturbation cause a significant change in RRP36 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SBDS is perturbed and the expression of RRP36 is measured. Does this perturbation cause a significant change in RRP36 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4910
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MFN2 is associated with a significant change in G0S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MFN2 is associated with a significant change in G0S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32745
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COX15 is perturbed and the expression of TGFBI is measured. Determine whether TGFBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COX15 is perturbed and the expression of TGFBI is measured. Determine whether TGFBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112866
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS27A is perturbed and NADK2 expression is quantified. Does this perturbation result in a significant change in NADK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS27A is perturbed and NADK2 expression is quantified. Does this perturbation result in a significant change in NADK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101482
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in PYCR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GET3 is associated with a significant change in PYCR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61385
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RRS1 is perturbed and the expression of ITPR1 is measured. Does this perturbation cause a significant change in ITPR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RRS1 is perturbed and the expression of ITPR1 is measured. Does this perturbation cause a significant change in ITPR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55700
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KAT7 and examine the expression of SERPINB8. Does perturbing KAT7 lead to a significant change in SERPINB8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KAT7 and examine the expression of SERPINB8. Does perturbing KAT7 lead to a significant change in SERPINB8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84671
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDX46 and monitor ZNF605 expression. Decide whether this perturbation leads to a significant alteration in ZNF605 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDX46 and monitor ZNF605 expression. Decide whether this perturbation leads to a significant alteration in ZNF605 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1108
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LARS2 is perturbed and WDYHV1 expression is quantified. Does this perturbation result in a significant change in WDYHV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LARS2 is perturbed and WDYHV1 expression is quantified. Does this perturbation result in a significant change in WDYHV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64392
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBA1C is perturbed and the expression of GNA13 is measured. Determine whether GNA13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBA1C is perturbed and the expression of GNA13 is measured. Determine whether GNA13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85866
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLASRP and examine the expression of SSPN. Does perturbing CLASRP lead to a significant change in SSPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLASRP and examine the expression of SSPN. Does perturbing CLASRP lead to a significant change in SSPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63951
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS34, does the expression profile of FBN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS34, does the expression profile of FBN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61227
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OXA1L is perturbed and the expression of CASP6 is measured. Does this perturbation cause a significant change in CASP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OXA1L is perturbed and the expression of CASP6 is measured. Does this perturbation cause a significant change in CASP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72710
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPC24 is associated with a significant change in FBXW11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPC24 is associated with a significant change in FBXW11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28015
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DUT and monitor WASHC2A expression. Decide whether this perturbation leads to a significant alteration in WASHC2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DUT and monitor WASHC2A expression. Decide whether this perturbation leads to a significant alteration in WASHC2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103938
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABT1 and examine the expression of PAPPA. Does perturbing ABT1 lead to a significant change in PAPPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABT1 and examine the expression of PAPPA. Does perturbing ABT1 lead to a significant change in PAPPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120901
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GEMIN7 is perturbed and the expression of RBM22 is measured. Determine whether RBM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GEMIN7 is perturbed and the expression of RBM22 is measured. Determine whether RBM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119926
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and ZCCHC9 expression is observed. Does this perturbation lead to a significant difference in ZCCHC9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and ZCCHC9 expression is observed. Does this perturbation lead to a significant difference in ZCCHC9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66183
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDX23 and monitor FAS expression. Decide whether this perturbation leads to a significant alteration in FAS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDX23 and monitor FAS expression. Decide whether this perturbation leads to a significant alteration in FAS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45468
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRRT is perturbed and SERPINE1 expression is observed. Does this perturbation lead to a significant difference in SERPINE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRRT is perturbed and SERPINE1 expression is observed. Does this perturbation lead to a significant difference in SERPINE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57893
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF2H4, does the expression profile of SYNGR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GTF2H4, does the expression profile of SYNGR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61987
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIS18A is perturbed and FRA10AC1 expression is observed. Does this perturbation lead to a significant difference in FRA10AC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIS18A is perturbed and FRA10AC1 expression is observed. Does this perturbation lead to a significant difference in FRA10AC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109173
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRRT, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRRT, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57877
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ORC1 and then measure expression of TRMT13. Does this perturbation cause a significant change in TRMT13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ORC1 and then measure expression of TRMT13. Does this perturbation cause a significant change in TRMT13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50124
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LDB1 and then measure expression of SPRED1. Does this perturbation cause a significant change in SPRED1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LDB1 and then measure expression of SPRED1. Does this perturbation cause a significant change in SPRED1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111074
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAP3 is perturbed and the expression of COQ4 is measured. Does this perturbation cause a significant change in COQ4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAP3 is perturbed and the expression of COQ4 is measured. Does this perturbation cause a significant change in COQ4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24830
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2Z is perturbed and RBM19 expression is measured. Determine whether RBM19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2Z is perturbed and RBM19 expression is measured. Determine whether RBM19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61479
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIP7 is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIP7 is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93125
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLRX3 and then measure expression of NOM1. Does this perturbation cause a significant change in NOM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLRX3 and then measure expression of NOM1. Does this perturbation cause a significant change in NOM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11584
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LAS1L and monitor RNF114 expression. Decide whether this perturbation leads to a significant alteration in RNF114 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LAS1L and monitor RNF114 expression. Decide whether this perturbation leads to a significant alteration in RNF114 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39088
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACIN1 is associated with a significant change in SLC17A5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ACIN1 is associated with a significant change in SLC17A5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20725
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMG6 is perturbed and the expression of TSC2 is measured. Determine whether TSC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMG6 is perturbed and the expression of TSC2 is measured. Determine whether TSC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53736
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCAR1 is perturbed and the expression of ZIM3 is measured. Determine whether ZIM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCAR1 is perturbed and the expression of ZIM3 is measured. Determine whether ZIM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71876
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in NCOA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in NCOA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122695
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RAD21 is perturbed and WDR45 expression is measured. Determine whether WDR45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RAD21 is perturbed and WDR45 expression is measured. Determine whether WDR45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37579
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL41 is perturbed and the expression of CENPQ is measured. Does this perturbation cause a significant change in CENPQ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL41 is perturbed and the expression of CENPQ is measured. Does this perturbation cause a significant change in CENPQ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50010
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF3J is perturbed and the expression of PNRC1 is measured. Determine whether PNRC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF3J is perturbed and the expression of PNRC1 is measured. Determine whether PNRC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12216
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL36AL is perturbed and CCDC28B expression is quantified. Does this perturbation result in a significant change in CCDC28B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL36AL is perturbed and CCDC28B expression is quantified. Does this perturbation result in a significant change in CCDC28B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80472
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PUF60 is perturbed and PLPP5 expression is observed. Does this perturbation lead to a significant difference in PLPP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PUF60 is perturbed and PLPP5 expression is observed. Does this perturbation lead to a significant difference in PLPP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8803
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KDM2A is perturbed and MTHFD2L expression is quantified. Does this perturbation result in a significant change in MTHFD2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KDM2A is perturbed and MTHFD2L expression is quantified. Does this perturbation result in a significant change in MTHFD2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3532
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MBD3 is perturbed and the expression of CARD6 is measured. Does this perturbation cause a significant change in CARD6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MBD3 is perturbed and the expression of CARD6 is measured. Does this perturbation cause a significant change in CARD6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76530
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEN1 and monitor MIR210HG expression. Decide whether this perturbation leads to a significant alteration in MIR210HG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEN1 and monitor MIR210HG expression. Decide whether this perturbation leads to a significant alteration in MIR210HG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1028
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZFC3H1 is perturbed and the expression of GPALPP1 is measured. Determine whether GPALPP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZFC3H1 is perturbed and the expression of GPALPP1 is measured. Determine whether GPALPP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32396
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2E is perturbed and PCSK1N expression is quantified. Does this perturbation result in a significant change in PCSK1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2E is perturbed and PCSK1N expression is quantified. Does this perturbation result in a significant change in PCSK1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46012
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NOM1 is perturbed and DNAJB1 expression is quantified. Does this perturbation result in a significant change in DNAJB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NOM1 is perturbed and DNAJB1 expression is quantified. Does this perturbation result in a significant change in DNAJB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68322
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIER1 is associated with a significant change in CLPP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIER1 is associated with a significant change in CLPP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26725
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF4E is perturbed and FBXW4 expression is quantified. Does this perturbation result in a significant change in FBXW4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF4E is perturbed and FBXW4 expression is quantified. Does this perturbation result in a significant change in FBXW4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7362
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NELFE is associated with a significant change in CLIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NELFE is associated with a significant change in CLIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51185
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ELL and monitor LIN37 expression. Decide whether this perturbation leads to a significant alteration in LIN37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ELL and monitor LIN37 expression. Decide whether this perturbation leads to a significant alteration in LIN37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31518
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL43 is perturbed and DBF4B expression is quantified. Does this perturbation result in a significant change in DBF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL43 is perturbed and DBF4B expression is quantified. Does this perturbation result in a significant change in DBF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39152
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED22 and then measure expression of PBXIP1. Does this perturbation cause a significant change in PBXIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED22 and then measure expression of PBXIP1. Does this perturbation cause a significant change in PBXIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80044
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, INPPL1 is perturbed and PFKFB4 expression is measured. Determine whether PFKFB4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, INPPL1 is perturbed and PFKFB4 expression is measured. Determine whether PFKFB4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104569
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAU2 is perturbed and the expression of NEAT1 is measured. Determine whether NEAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAU2 is perturbed and the expression of NEAT1 is measured. Determine whether NEAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113646
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPLP2 and then measure expression of SIK2. Does this perturbation cause a significant change in SIK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPLP2 and then measure expression of SIK2. Does this perturbation cause a significant change in SIK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90344
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOR2A and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TOR2A and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81074
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLP1 is perturbed and TTL expression is measured. Determine whether TTL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLP1 is perturbed and TTL expression is measured. Determine whether TTL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118069
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HIST2H2AC is perturbed and SNX2 expression is quantified. Does this perturbation result in a significant change in SNX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HIST2H2AC is perturbed and SNX2 expression is quantified. Does this perturbation result in a significant change in SNX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112922
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPP30 is perturbed and DENND5B expression is observed. Does this perturbation lead to a significant difference in DENND5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPP30 is perturbed and DENND5B expression is observed. Does this perturbation lead to a significant difference in DENND5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113783
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NSUN4 is perturbed and TMEM132A expression is observed. Does this perturbation lead to a significant difference in TMEM132A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NSUN4 is perturbed and TMEM132A expression is observed. Does this perturbation lead to a significant difference in TMEM132A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10733
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NSA2 is perturbed and HABP4 expression is quantified. Does this perturbation result in a significant change in HABP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NSA2 is perturbed and HABP4 expression is quantified. Does this perturbation result in a significant change in HABP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59442
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB4A is perturbed and the expression of PYROXD1 is measured. Determine whether PYROXD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB4A is perturbed and the expression of PYROXD1 is measured. Determine whether PYROXD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46086
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP54, does the expression profile of EFEMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NUP54, does the expression profile of EFEMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64077
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIPIN is perturbed and the expression of THOC5 is measured. Determine whether THOC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIPIN is perturbed and the expression of THOC5 is measured. Determine whether THOC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103896
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POT1 is perturbed and ZNHIT1 expression is quantified. Does this perturbation result in a significant change in ZNHIT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POT1 is perturbed and ZNHIT1 expression is quantified. Does this perturbation result in a significant change in ZNHIT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116642
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IPO9 is perturbed and the expression of POLR3GL is measured. Does this perturbation cause a significant change in POLR3GL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IPO9 is perturbed and the expression of POLR3GL is measured. Does this perturbation cause a significant change in POLR3GL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75550
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SETX and monitor ATP13A2 expression. Decide whether this perturbation leads to a significant alteration in ATP13A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SETX and monitor ATP13A2 expression. Decide whether this perturbation leads to a significant alteration in ATP13A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40708
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LUC7L3 is perturbed and the expression of MTCL1 is measured. Does this perturbation cause a significant change in MTCL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LUC7L3 is perturbed and the expression of MTCL1 is measured. Does this perturbation cause a significant change in MTCL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15660
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBM33 is perturbed and CD55 expression is observed. Does this perturbation lead to a significant difference in CD55 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBM33 is perturbed and CD55 expression is observed. Does this perturbation lead to a significant difference in CD55 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41183
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD2 is perturbed and the expression of UEVLD is measured. Determine whether UEVLD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD2 is perturbed and the expression of UEVLD is measured. Determine whether UEVLD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122366
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG2 is perturbed and TEAD3 expression is quantified. Does this perturbation result in a significant change in TEAD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ALG2 is perturbed and TEAD3 expression is quantified. Does this perturbation result in a significant change in TEAD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1822
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPA2 is perturbed and the expression of RNF139 is measured. Does this perturbation cause a significant change in RNF139 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPA2 is perturbed and the expression of RNF139 is measured. Does this perturbation cause a significant change in RNF139 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56650
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RAD51C is perturbed and the expression of BBS4 is measured. Does this perturbation cause a significant change in BBS4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RAD51C is perturbed and the expression of BBS4 is measured. Does this perturbation cause a significant change in BBS4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105520
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP54 is associated with a significant change in EFEMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP54 is associated with a significant change in EFEMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64075
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CRKL and examine the expression of MBOAT2. Does perturbing CRKL lead to a significant change in MBOAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CRKL and examine the expression of MBOAT2. Does perturbing CRKL lead to a significant change in MBOAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91781
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHCY and then measure expression of CEP57. Does this perturbation cause a significant change in CEP57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHCY and then measure expression of CEP57. Does this perturbation cause a significant change in CEP57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56524
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP160 is perturbed and RNF215 expression is observed. Does this perturbation lead to a significant difference in RNF215 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP160 is perturbed and RNF215 expression is observed. Does this perturbation lead to a significant difference in RNF215 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16863
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANKRD17 and examine the expression of FKTN. Does perturbing ANKRD17 lead to a significant change in FKTN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ANKRD17 and examine the expression of FKTN. Does perturbing ANKRD17 lead to a significant change in FKTN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90281
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM10 and examine the expression of SCMH1. Does perturbing TIMM10 lead to a significant change in SCMH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM10 and examine the expression of SCMH1. Does perturbing TIMM10 lead to a significant change in SCMH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16381
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1B2 and examine the expression of TBCK. Does perturbing ATP6V1B2 lead to a significant change in TBCK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1B2 and examine the expression of TBCK. Does perturbing ATP6V1B2 lead to a significant change in TBCK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60741
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TADA2B is perturbed and HP1BP3 expression is measured. Determine whether HP1BP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TADA2B is perturbed and HP1BP3 expression is measured. Determine whether HP1BP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33549
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED19 and examine the expression of GNG5. Does perturbing MED19 lead to a significant change in GNG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED19 and examine the expression of GNG5. Does perturbing MED19 lead to a significant change in GNG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29561
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb WDR36 and monitor BCKDHB expression. Decide whether this perturbation leads to a significant alteration in BCKDHB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb WDR36 and monitor BCKDHB expression. Decide whether this perturbation leads to a significant alteration in BCKDHB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90948
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NAF1 and monitor PLSCR3 expression. Decide whether this perturbation leads to a significant alteration in PLSCR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NAF1 and monitor PLSCR3 expression. Decide whether this perturbation leads to a significant alteration in PLSCR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93838
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HERC1 and examine the expression of CDKN1A. Does perturbing HERC1 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HERC1 and examine the expression of CDKN1A. Does perturbing HERC1 lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43661
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSCB is perturbed and the expression of PIP5K1C is measured. Does this perturbation cause a significant change in PIP5K1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSCB is perturbed and the expression of PIP5K1C is measured. Does this perturbation cause a significant change in PIP5K1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23430
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PHF5A is perturbed and the expression of TXNL4B is measured. Does this perturbation cause a significant change in TXNL4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PHF5A is perturbed and the expression of TXNL4B is measured. Does this perturbation cause a significant change in TXNL4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98990
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FAU is perturbed and the expression of CNOT10 is measured. Does this perturbation cause a significant change in CNOT10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FAU is perturbed and the expression of CNOT10 is measured. Does this perturbation cause a significant change in CNOT10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34140
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb URM1 and examine the expression of CENPL. Does perturbing URM1 lead to a significant change in CENPL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb URM1 and examine the expression of CENPL. Does perturbing URM1 lead to a significant change in CENPL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103581
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DYNC1I2 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DYNC1I2 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116092
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ORC3 is perturbed and CYB5R4 expression is measured. Determine whether CYB5R4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ORC3 is perturbed and CYB5R4 expression is measured. Determine whether CYB5R4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51449
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VPS33A is perturbed and MYSM1 expression is quantified. Does this perturbation result in a significant change in MYSM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, VPS33A is perturbed and MYSM1 expression is quantified. Does this perturbation result in a significant change in MYSM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21172
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EXOC7 and monitor ANKS1A expression. Decide whether this perturbation leads to a significant alteration in ANKS1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EXOC7 and monitor ANKS1A expression. Decide whether this perturbation leads to a significant alteration in ANKS1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76718
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NLE1 is associated with a significant change in SERTAD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NLE1 is associated with a significant change in SERTAD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71225
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TUBE1 is perturbed and the expression of SEMA5A is measured. Does this perturbation cause a significant change in SEMA5A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TUBE1 is perturbed and the expression of SEMA5A is measured. Does this perturbation cause a significant change in SEMA5A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38360
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FNBP4 is perturbed and PALMD expression is measured. Determine whether PALMD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FNBP4 is perturbed and PALMD expression is measured. Determine whether PALMD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41799
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FBXO5 and examine the expression of MT1M. Does perturbing FBXO5 lead to a significant change in MT1M expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FBXO5 and examine the expression of MT1M. Does perturbing FBXO5 lead to a significant change in MT1M expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123041
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KPNA6 is associated with a significant change in TP53TG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KPNA6 is associated with a significant change in TP53TG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12485
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CYFIP1 and monitor RDH10 expression. Decide whether this perturbation leads to a significant alteration in RDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CYFIP1 and monitor RDH10 expression. Decide whether this perturbation leads to a significant alteration in RDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107998
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RCCD1 is perturbed and the expression of NCSTN is measured. Does this perturbation cause a significant change in NCSTN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RCCD1 is perturbed and the expression of NCSTN is measured. Does this perturbation cause a significant change in NCSTN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15300
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIN and monitor NARS expression. Decide whether this perturbation leads to a significant alteration in NARS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIN and monitor NARS expression. Decide whether this perturbation leads to a significant alteration in NARS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90458
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1D and examine the expression of DDIT4. Does perturbing ATP6V1D lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP6V1D and examine the expression of DDIT4. Does perturbing ATP6V1D lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12621
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF143 is perturbed and the expression of GOLGA1 is measured. Determine whether GOLGA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF143 is perturbed and the expression of GOLGA1 is measured. Determine whether GOLGA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42306
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EFR3A is perturbed and SPSB1 expression is quantified. Does this perturbation result in a significant change in SPSB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EFR3A is perturbed and SPSB1 expression is quantified. Does this perturbation result in a significant change in SPSB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47232
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IER5. Does this perturbation cause a significant change in IER5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IER5. Does this perturbation cause a significant change in IER5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49794
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL51 is perturbed and ZBTB20 expression is measured. Determine whether ZBTB20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL51 is perturbed and ZBTB20 expression is measured. Determine whether ZBTB20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106639
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARPC2, does the expression profile of ITGA11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARPC2, does the expression profile of ITGA11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52967
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCNQ and then measure expression of PRAF2. Does this perturbation cause a significant change in PRAF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCNQ and then measure expression of PRAF2. Does this perturbation cause a significant change in PRAF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89154
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3H and then measure expression of FLII. Does this perturbation cause a significant change in FLII expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3H and then measure expression of FLII. Does this perturbation cause a significant change in FLII expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91474
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS18A and examine the expression of MTERF4. Does perturbing MRPS18A lead to a significant change in MTERF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS18A and examine the expression of MTERF4. Does perturbing MRPS18A lead to a significant change in MTERF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85511
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PABPC1 is perturbed and LONP2 expression is quantified. Does this perturbation result in a significant change in LONP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PABPC1 is perturbed and LONP2 expression is quantified. Does this perturbation result in a significant change in LONP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70602
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SETX is perturbed and the expression of ERO1A is measured. Does this perturbation cause a significant change in ERO1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SETX is perturbed and the expression of ERO1A is measured. Does this perturbation cause a significant change in ERO1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40730
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS17 is perturbed and ZMYM5 expression is quantified. Does this perturbation result in a significant change in ZMYM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS17 is perturbed and ZMYM5 expression is quantified. Does this perturbation result in a significant change in ZMYM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17122
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSTF3 is perturbed and FAM32A expression is measured. Determine whether FAM32A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSTF3 is perturbed and FAM32A expression is measured. Determine whether FAM32A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49619
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS12, does the expression profile of C1GALT1C1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INTS12, does the expression profile of C1GALT1C1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89147
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCR and then measure expression of GBA. Does this perturbation cause a significant change in GBA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCR and then measure expression of GBA. Does this perturbation cause a significant change in GBA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22854
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, METTL16 is perturbed and ITPRID2 expression is measured. Determine whether ITPRID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, METTL16 is perturbed and ITPRID2 expression is measured. Determine whether ITPRID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53019
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSDE1 is perturbed and EEF1AKMT4 expression is quantified. Does this perturbation result in a significant change in EEF1AKMT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSDE1 is perturbed and EEF1AKMT4 expression is quantified. Does this perturbation result in a significant change in EEF1AKMT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101322
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DMAP1, does the expression profile of EPHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DMAP1, does the expression profile of EPHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116697
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP56 is perturbed and the expression of HIVEP1 is measured. Does this perturbation cause a significant change in HIVEP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NOP56 is perturbed and the expression of HIVEP1 is measured. Does this perturbation cause a significant change in HIVEP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15690
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NMD3 is associated with a significant change in MAN2B1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NMD3 is associated with a significant change in MAN2B1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93625
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCNM1 and then measure expression of C12orf4. Does this perturbation cause a significant change in C12orf4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCNM1 and then measure expression of C12orf4. Does this perturbation cause a significant change in C12orf4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57724
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP2CB is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP2CB is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10100
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POP4 and monitor CDH10 expression. Decide whether this perturbation leads to a significant alteration in CDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POP4 and monitor CDH10 expression. Decide whether this perturbation leads to a significant alteration in CDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24388
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of SCFD1. Does perturbing SAMM50 lead to a significant change in SCFD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of SCFD1. Does perturbing SAMM50 lead to a significant change in SCFD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120611
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT1 and examine the expression of LBR. Does perturbing ZNHIT1 lead to a significant change in LBR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNHIT1 and examine the expression of LBR. Does perturbing ZNHIT1 lead to a significant change in LBR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83601
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NHP2 is perturbed and the expression of GPRC5C is measured. Does this perturbation cause a significant change in GPRC5C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NHP2 is perturbed and the expression of GPRC5C is measured. Does this perturbation cause a significant change in GPRC5C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96410
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMEM127 and monitor MED11 expression. Decide whether this perturbation leads to a significant alteration in MED11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMEM127 and monitor MED11 expression. Decide whether this perturbation leads to a significant alteration in MED11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43998
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAC3 is associated with a significant change in PLAC9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAC3 is associated with a significant change in PLAC9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44665
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP98 is associated with a significant change in CEP112 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUP98 is associated with a significant change in CEP112 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27275
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PHB is perturbed and the expression of OGA is measured. Determine whether OGA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PHB is perturbed and the expression of OGA is measured. Determine whether OGA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26776
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CPNE7 and monitor MCC expression. Decide whether this perturbation leads to a significant alteration in MCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CPNE7 and monitor MCC expression. Decide whether this perturbation leads to a significant alteration in MCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17778
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2I is perturbed and ZCCHC8 expression is measured. Determine whether ZCCHC8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBE2I is perturbed and ZCCHC8 expression is measured. Determine whether ZCCHC8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77729
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SF3A1 is perturbed and the expression of SLC6A8 is measured. Determine whether SLC6A8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SF3A1 is perturbed and the expression of SLC6A8 is measured. Determine whether SLC6A8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21496
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLI4 is perturbed and CCNDBP1 expression is observed. Does this perturbation lead to a significant difference in CCNDBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLI4 is perturbed and CCNDBP1 expression is observed. Does this perturbation lead to a significant difference in CCNDBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19113
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SSBP3, does the expression profile of IFT122 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SSBP3, does the expression profile of IFT122 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7157
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NELFCD is perturbed and CHST11 expression is quantified. Does this perturbation result in a significant change in CHST11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NELFCD is perturbed and CHST11 expression is quantified. Does this perturbation result in a significant change in CHST11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46532
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPH1 is perturbed and the expression of EMC1 is measured. Determine whether EMC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNRNPH1 is perturbed and the expression of EMC1 is measured. Determine whether EMC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22006
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTBP1 and examine the expression of CHCHD3. Does perturbing PTBP1 lead to a significant change in CHCHD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTBP1 and examine the expression of CHCHD3. Does perturbing PTBP1 lead to a significant change in CHCHD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76161
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPAN is perturbed and the expression of TAOK3 is measured. Determine whether TAOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPAN is perturbed and the expression of TAOK3 is measured. Determine whether TAOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117216
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGK1, does the expression profile of RNF111 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PGK1, does the expression profile of RNF111 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89667
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3C5 is perturbed and RPS28 expression is quantified. Does this perturbation result in a significant change in RPS28 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3C5 is perturbed and RPS28 expression is quantified. Does this perturbation result in a significant change in RPS28 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117452
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCNC and examine the expression of CHPT1. Does perturbing CCNC lead to a significant change in CHPT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCNC and examine the expression of CHPT1. Does perturbing CCNC lead to a significant change in CHPT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81951
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNHIT3 is perturbed and DUSP4 expression is observed. Does this perturbation lead to a significant difference in DUSP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNHIT3 is perturbed and DUSP4 expression is observed. Does this perturbation lead to a significant difference in DUSP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48223
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRAPPC5 is perturbed and TMEM267 expression is quantified. Does this perturbation result in a significant change in TMEM267 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRAPPC5 is perturbed and TMEM267 expression is quantified. Does this perturbation result in a significant change in TMEM267 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91102
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BANP and examine the expression of ZNF688. Does perturbing BANP lead to a significant change in ZNF688 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BANP and examine the expression of ZNF688. Does perturbing BANP lead to a significant change in ZNF688 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121061
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNC1H1, does the expression profile of ELP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNC1H1, does the expression profile of ELP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98487
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DOLK is perturbed and the expression of FBXW7 is measured. Determine whether FBXW7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DOLK is perturbed and the expression of FBXW7 is measured. Determine whether FBXW7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36036
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DCTN2 and examine the expression of ZNF107. Does perturbing DCTN2 lead to a significant change in ZNF107 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DCTN2 and examine the expression of ZNF107. Does perturbing DCTN2 lead to a significant change in ZNF107 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83071
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TPX2 is perturbed and INTS10 expression is observed. Does this perturbation lead to a significant difference in INTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TPX2 is perturbed and INTS10 expression is observed. Does this perturbation lead to a significant difference in INTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115843
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SSU72 is perturbed and DENND10 expression is observed. Does this perturbation lead to a significant difference in DENND10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SSU72 is perturbed and DENND10 expression is observed. Does this perturbation lead to a significant difference in DENND10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59853
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHFR is perturbed and PCSK1N expression is observed. Does this perturbation lead to a significant difference in PCSK1N expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHFR is perturbed and PCSK1N expression is observed. Does this perturbation lead to a significant difference in PCSK1N expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103393
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF4A and monitor ORC5 expression. Decide whether this perturbation leads to a significant alteration in ORC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF4A and monitor ORC5 expression. Decide whether this perturbation leads to a significant alteration in ORC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55058
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SIN3A is perturbed and CHKB expression is quantified. Does this perturbation result in a significant change in CHKB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SIN3A is perturbed and CHKB expression is quantified. Does this perturbation result in a significant change in CHKB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73112
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM127 and examine the expression of RNF41. Does perturbing TMEM127 lead to a significant change in RNF41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM127 and examine the expression of RNF41. Does perturbing TMEM127 lead to a significant change in RNF41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43961
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEPCE is perturbed and the expression of ARID2 is measured. Does this perturbation cause a significant change in ARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEPCE is perturbed and the expression of ARID2 is measured. Does this perturbation cause a significant change in ARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109310
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF1, does the expression profile of HRH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF1, does the expression profile of HRH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101377
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM39, does the expression profile of NFKBIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBM39, does the expression profile of NFKBIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99837
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of WDR35. Does perturbing NVL lead to a significant change in WDR35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of WDR35. Does perturbing NVL lead to a significant change in WDR35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92201
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UXS1 is perturbed and FMR1 expression is measured. Determine whether FMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UXS1 is perturbed and FMR1 expression is measured. Determine whether FMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26539
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PKMYT1 is perturbed and AARSD1 expression is observed. Does this perturbation lead to a significant difference in AARSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PKMYT1 is perturbed and AARSD1 expression is observed. Does this perturbation lead to a significant difference in AARSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57033
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATXN10 is associated with a significant change in HLA-E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATXN10 is associated with a significant change in HLA-E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5425
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRA2B is perturbed and MALAT1 expression is measured. Determine whether MALAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRA2B is perturbed and MALAT1 expression is measured. Determine whether MALAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50409
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR2G is perturbed and the expression of LRPAP1 is measured. Determine whether LRPAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR2G is perturbed and the expression of LRPAP1 is measured. Determine whether LRPAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113716
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCDC59 is perturbed and the expression of SLC35F5 is measured. Does this perturbation cause a significant change in SLC35F5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCDC59 is perturbed and the expression of SLC35F5 is measured. Does this perturbation cause a significant change in SLC35F5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28710
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MSRB1 is perturbed and SDR39U1 expression is quantified. Does this perturbation result in a significant change in SDR39U1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MSRB1 is perturbed and SDR39U1 expression is quantified. Does this perturbation result in a significant change in SDR39U1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40212
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TXNL4B and examine the expression of FDXR. Does perturbing TXNL4B lead to a significant change in FDXR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TXNL4B and examine the expression of FDXR. Does perturbing TXNL4B lead to a significant change in FDXR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26101
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SDC1 and monitor ATF6 expression. Decide whether this perturbation leads to a significant alteration in ATF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SDC1 and monitor ATF6 expression. Decide whether this perturbation leads to a significant alteration in ATF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85738
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED6 and examine the expression of DHRSX. Does perturbing MED6 lead to a significant change in DHRSX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MED6 and examine the expression of DHRSX. Does perturbing MED6 lead to a significant change in DHRSX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108741
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPZ is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPZ is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91056
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTC4 and examine the expression of ATF1. Does perturbing TTC4 lead to a significant change in ATF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTC4 and examine the expression of ATF1. Does perturbing TTC4 lead to a significant change in ATF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37921
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KAT8, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KAT8, does the expression profile of ACTA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118397
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL2 is perturbed and the expression of OSTF1 is measured. Determine whether OSTF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL2 is perturbed and the expression of OSTF1 is measured. Determine whether OSTF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27596
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP214 and examine the expression of TP53I3. Does perturbing NUP214 lead to a significant change in TP53I3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUP214 and examine the expression of TP53I3. Does perturbing NUP214 lead to a significant change in TP53I3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103741
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD14 is perturbed and SETD5 expression is measured. Determine whether SETD5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD14 is perturbed and SETD5 expression is measured. Determine whether SETD5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64019
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL13A is perturbed and ATXN7L3B expression is measured. Determine whether ATXN7L3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL13A is perturbed and ATXN7L3B expression is measured. Determine whether ATXN7L3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98819
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DTL is perturbed and the expression of MAPKAPK5-AS1 is measured. Does this perturbation cause a significant change in MAPKAPK5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DTL is perturbed and the expression of MAPKAPK5-AS1 is measured. Does this perturbation cause a significant change in MAPKAPK5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88680
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, THOC2 is perturbed and the expression of MAPRE3 is measured. Determine whether MAPRE3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, THOC2 is perturbed and the expression of MAPRE3 is measured. Determine whether MAPRE3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86086
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS26 is associated with a significant change in NFXL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPS26 is associated with a significant change in NFXL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72635
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPG7 is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPG7 is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3889
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BRF1 is perturbed and TARS expression is quantified. Does this perturbation result in a significant change in TARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BRF1 is perturbed and TARS expression is quantified. Does this perturbation result in a significant change in TARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7922
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and CSNK1G2 expression is observed. Does this perturbation lead to a significant difference in CSNK1G2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and CSNK1G2 expression is observed. Does this perturbation lead to a significant difference in CSNK1G2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77323
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS4 and then measure expression of LTA4H. Does this perturbation cause a significant change in LTA4H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS4 and then measure expression of LTA4H. Does this perturbation cause a significant change in LTA4H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108814
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOB1 is perturbed and ALG1 expression is observed. Does this perturbation lead to a significant difference in ALG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOB1 is perturbed and ALG1 expression is observed. Does this perturbation lead to a significant difference in ALG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27983
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which METAP2 is perturbed and OAZ2 expression is observed. Does this perturbation lead to a significant difference in OAZ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which METAP2 is perturbed and OAZ2 expression is observed. Does this perturbation lead to a significant difference in OAZ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122933
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF3 is perturbed and the expression of TERF2 is measured. Does this perturbation cause a significant change in TERF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFAF3 is perturbed and the expression of TERF2 is measured. Does this perturbation cause a significant change in TERF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7940
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED11 is associated with a significant change in ZSCAN16-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED11 is associated with a significant change in ZSCAN16-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119815
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FBRSL1 is perturbed and the expression of SGIP1 is measured. Does this perturbation cause a significant change in SGIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FBRSL1 is perturbed and the expression of SGIP1 is measured. Does this perturbation cause a significant change in SGIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73670
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LAS1L is associated with a significant change in RNF114 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LAS1L is associated with a significant change in RNF114 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39085
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLE2 is perturbed and DSEL expression is quantified. Does this perturbation result in a significant change in DSEL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLE2 is perturbed and DSEL expression is quantified. Does this perturbation result in a significant change in DSEL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87282
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R8 is perturbed and the expression of SCFD2 is measured. Determine whether SCFD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R8 is perturbed and the expression of SCFD2 is measured. Determine whether SCFD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33656
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFB10 is perturbed and the expression of METTL2A is measured. Determine whether METTL2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFB10 is perturbed and the expression of METTL2A is measured. Determine whether METTL2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104796
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CIAO1 and then measure expression of EEPD1. Does this perturbation cause a significant change in EEPD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CIAO1 and then measure expression of EEPD1. Does this perturbation cause a significant change in EEPD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9734
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF84, does the expression profile of SYVN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF84, does the expression profile of SYVN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114447
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL51 and examine the expression of SLC6A8. Does perturbing MRPL51 lead to a significant change in SLC6A8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL51 and examine the expression of SLC6A8. Does perturbing MRPL51 lead to a significant change in SLC6A8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106641
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NSMCE1 and monitor CMTM6 expression. Decide whether this perturbation leads to a significant alteration in CMTM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NSMCE1 and monitor CMTM6 expression. Decide whether this perturbation leads to a significant alteration in CMTM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29928
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LETM1 is perturbed and the expression of SLC2A8 is measured. Does this perturbation cause a significant change in SLC2A8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LETM1 is perturbed and the expression of SLC2A8 is measured. Does this perturbation cause a significant change in SLC2A8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59790
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZCCHC9 is perturbed and PITPNB expression is quantified. Does this perturbation result in a significant change in PITPNB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZCCHC9 is perturbed and PITPNB expression is quantified. Does this perturbation result in a significant change in PITPNB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78692
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MBTPS1 and then measure expression of KYAT3. Does this perturbation cause a significant change in KYAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MBTPS1 and then measure expression of KYAT3. Does this perturbation cause a significant change in KYAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10824
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COA5 is perturbed and TCP11L1 expression is quantified. Does this perturbation result in a significant change in TCP11L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COA5 is perturbed and TCP11L1 expression is quantified. Does this perturbation result in a significant change in TCP11L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84512
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CYFIP1 is perturbed and the expression of RDH10 is measured. Determine whether RDH10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CYFIP1 is perturbed and the expression of RDH10 is measured. Determine whether RDH10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107996
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFAB1 is perturbed and MBNL2 expression is quantified. Does this perturbation result in a significant change in MBNL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NDUFAB1 is perturbed and MBNL2 expression is quantified. Does this perturbation result in a significant change in MBNL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42402
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNLL1, does the expression profile of GRINA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DYNLL1, does the expression profile of GRINA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94277
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPAP3 is perturbed and MAPK1 expression is observed. Does this perturbation lead to a significant difference in MAPK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPAP3 is perturbed and MAPK1 expression is observed. Does this perturbation lead to a significant difference in MAPK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87903
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP53RK and then measure expression of IL1B. Does this perturbation cause a significant change in IL1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP53RK and then measure expression of IL1B. Does this perturbation cause a significant change in IL1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14704
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDR39U1 is perturbed and UBE2W expression is observed. Does this perturbation lead to a significant difference in UBE2W expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDR39U1 is perturbed and UBE2W expression is observed. Does this perturbation lead to a significant difference in UBE2W expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70943
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBA3 is perturbed and the expression of SLC48A1 is measured. Determine whether SLC48A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBA3 is perturbed and the expression of SLC48A1 is measured. Determine whether SLC48A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39856
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP1R10 and then measure expression of TUSC3. Does this perturbation cause a significant change in TUSC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP1R10 and then measure expression of TUSC3. Does this perturbation cause a significant change in TUSC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52274
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5ME is perturbed and UQCC1 expression is measured. Determine whether UQCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5ME is perturbed and UQCC1 expression is measured. Determine whether UQCC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86129
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COA5 and examine the expression of BLOC1S5. Does perturbing COA5 lead to a significant change in BLOC1S5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COA5 and examine the expression of BLOC1S5. Does perturbing COA5 lead to a significant change in BLOC1S5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84521
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDCD7 is perturbed and the expression of BAG3 is measured. Does this perturbation cause a significant change in BAG3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDCD7 is perturbed and the expression of BAG3 is measured. Does this perturbation cause a significant change in BAG3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74890
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CYC1. Does this perturbation cause a significant change in CYC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CYC1. Does this perturbation cause a significant change in CYC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119134
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C9orf78 and monitor EMC4 expression. Decide whether this perturbation leads to a significant alteration in EMC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C9orf78 and monitor EMC4 expression. Decide whether this perturbation leads to a significant alteration in EMC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29518
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SENP6 is associated with a significant change in FOXJ3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SENP6 is associated with a significant change in FOXJ3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80385
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA5 is associated with a significant change in CDC16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBA5 is associated with a significant change in CDC16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78795
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBE2I, does the expression profile of ZCCHC8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBE2I, does the expression profile of ZCCHC8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77727
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, E2F6 is perturbed and XPA expression is measured. Determine whether XPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, E2F6 is perturbed and XPA expression is measured. Determine whether XPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40919
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAA15 and then measure expression of RTL8C. Does this perturbation cause a significant change in RTL8C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAA15 and then measure expression of RTL8C. Does this perturbation cause a significant change in RTL8C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64554
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLRX3 and examine the expression of PLAT. Does perturbing GLRX3 lead to a significant change in PLAT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLRX3 and examine the expression of PLAT. Does perturbing GLRX3 lead to a significant change in PLAT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11561
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD6 and monitor BRD1 expression. Decide whether this perturbation leads to a significant alteration in BRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD6 and monitor BRD1 expression. Decide whether this perturbation leads to a significant alteration in BRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78718
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GET1 and then measure expression of DOT1L. Does this perturbation cause a significant change in DOT1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GET1 and then measure expression of DOT1L. Does this perturbation cause a significant change in DOT1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21554
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCAPH is perturbed and STX6 expression is measured. Determine whether STX6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCAPH is perturbed and STX6 expression is measured. Determine whether STX6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24789
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AURKAIP1 is perturbed and CSPP1 expression is quantified. Does this perturbation result in a significant change in CSPP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AURKAIP1 is perturbed and CSPP1 expression is quantified. Does this perturbation result in a significant change in CSPP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65142
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC6 and then measure expression of LRPAP1. Does this perturbation cause a significant change in LRPAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDC6 and then measure expression of LRPAP1. Does this perturbation cause a significant change in LRPAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5674
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB10 is perturbed and RPL14 expression is measured. Determine whether RPL14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB10 is perturbed and RPL14 expression is measured. Determine whether RPL14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9499
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUP205 is perturbed and the expression of CDH6 is measured. Does this perturbation cause a significant change in CDH6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NUP205 is perturbed and the expression of CDH6 is measured. Does this perturbation cause a significant change in CDH6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103620
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DYNLL2 and monitor DUSP4 expression. Decide whether this perturbation leads to a significant alteration in DUSP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DYNLL2 and monitor DUSP4 expression. Decide whether this perturbation leads to a significant alteration in DUSP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69248
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRPA1 is perturbed and the expression of INTS5 is measured. Determine whether INTS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNRPA1 is perturbed and the expression of INTS5 is measured. Determine whether INTS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25136
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CWC15 is perturbed and EBAG9 expression is observed. Does this perturbation lead to a significant difference in EBAG9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CWC15 is perturbed and EBAG9 expression is observed. Does this perturbation lead to a significant difference in EBAG9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78103
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RAC1 and then measure expression of CAPZA1. Does this perturbation cause a significant change in CAPZA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RAC1 and then measure expression of CAPZA1. Does this perturbation cause a significant change in CAPZA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110864
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, N6AMT1 is perturbed and the expression of CEP57L1 is measured. Determine whether CEP57L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, N6AMT1 is perturbed and the expression of CEP57L1 is measured. Determine whether CEP57L1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2456
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL36 is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPL36 is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3232
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LEO1 is perturbed and the expression of RBP1 is measured. Determine whether RBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LEO1 is perturbed and the expression of RBP1 is measured. Determine whether RBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34346
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD12 and then measure expression of AP2B1. Does this perturbation cause a significant change in AP2B1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD12 and then measure expression of AP2B1. Does this perturbation cause a significant change in AP2B1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87594
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIN and examine the expression of PI4K2A. Does perturbing KIN lead to a significant change in PI4K2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIN and examine the expression of PI4K2A. Does perturbing KIN lead to a significant change in PI4K2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90461
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CWC25 is perturbed and CMTR1 expression is measured. Determine whether CMTR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CWC25 is perturbed and CMTR1 expression is measured. Determine whether CMTR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65249
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB8 is perturbed and the expression of NOA1 is measured. Does this perturbation cause a significant change in NOA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB8 is perturbed and the expression of NOA1 is measured. Does this perturbation cause a significant change in NOA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70200
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TUBE1 and then measure expression of C2orf49. Does this perturbation cause a significant change in C2orf49 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TUBE1 and then measure expression of C2orf49. Does this perturbation cause a significant change in C2orf49 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38374
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of SLC35F6. Does perturbing NVL lead to a significant change in SLC35F6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of SLC35F6. Does perturbing NVL lead to a significant change in SLC35F6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92191
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ANKS6 and monitor TSC1 expression. Decide whether this perturbation leads to a significant alteration in TSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ANKS6 and monitor TSC1 expression. Decide whether this perturbation leads to a significant alteration in TSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43578
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of F8A1, does the expression profile of MFF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of F8A1, does the expression profile of MFF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25897
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ORC4, does the expression profile of FDXR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ORC4, does the expression profile of FDXR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39027
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF2H1 is perturbed and STYX expression is quantified. Does this perturbation result in a significant change in STYX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF2H1 is perturbed and STYX expression is quantified. Does this perturbation result in a significant change in STYX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110732
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS11 is perturbed and RTCA expression is observed. Does this perturbation lead to a significant difference in RTCA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPS11 is perturbed and RTCA expression is observed. Does this perturbation lead to a significant difference in RTCA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77873
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL24 is perturbed and LENG8 expression is observed. Does this perturbation lead to a significant difference in LENG8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL24 is perturbed and LENG8 expression is observed. Does this perturbation lead to a significant difference in LENG8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14453
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDHC is perturbed and ARIH2 expression is observed. Does this perturbation lead to a significant difference in ARIH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDHC is perturbed and ARIH2 expression is observed. Does this perturbation lead to a significant difference in ARIH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119343
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX37 is associated with a significant change in NUDT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX37 is associated with a significant change in NUDT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91865
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPC and examine the expression of HOOK2. Does perturbing CENPC lead to a significant change in HOOK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CENPC and examine the expression of HOOK2. Does perturbing CENPC lead to a significant change in HOOK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119561
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR12 is perturbed and the expression of NACC2 is measured. Does this perturbation cause a significant change in NACC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR12 is perturbed and the expression of NACC2 is measured. Does this perturbation cause a significant change in NACC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71790
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM25 and examine the expression of PRKD3. Does perturbing RBM25 lead to a significant change in PRKD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM25 and examine the expression of PRKD3. Does perturbing RBM25 lead to a significant change in PRKD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29811
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP7 is perturbed and HSD17B11 expression is quantified. Does this perturbation result in a significant change in HSD17B11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP7 is perturbed and HSD17B11 expression is quantified. Does this perturbation result in a significant change in HSD17B11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101832
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PIAS4 is perturbed and the expression of FAT4 is measured. Determine whether FAT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PIAS4 is perturbed and the expression of FAT4 is measured. Determine whether FAT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37916
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDT1, does the expression profile of EEF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDT1, does the expression profile of EEF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21117
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of GCDH. Does perturbing AARS lead to a significant change in GCDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of GCDH. Does perturbing AARS lead to a significant change in GCDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94591
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAPC4 is perturbed and ADAM23 expression is measured. Determine whether ADAM23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAPC4 is perturbed and ADAM23 expression is measured. Determine whether ADAM23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48179
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARMC6 and examine the expression of ERBB2. Does perturbing ARMC6 lead to a significant change in ERBB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARMC6 and examine the expression of ERBB2. Does perturbing ARMC6 lead to a significant change in ERBB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58351
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL14 is associated with a significant change in NIT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL14 is associated with a significant change in NIT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69295
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOP10 is perturbed and COPZ2 expression is observed. Does this perturbation lead to a significant difference in COPZ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOP10 is perturbed and COPZ2 expression is observed. Does this perturbation lead to a significant difference in COPZ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120173
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM161B is perturbed and the expression of APBB1IP is measured. Does this perturbation cause a significant change in APBB1IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM161B is perturbed and the expression of APBB1IP is measured. Does this perturbation cause a significant change in APBB1IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38970
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GABPB1 and monitor MDM2 expression. Decide whether this perturbation leads to a significant alteration in MDM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GABPB1 and monitor MDM2 expression. Decide whether this perturbation leads to a significant alteration in MDM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98098
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNMT1 is perturbed and ATP10D expression is observed. Does this perturbation lead to a significant difference in ATP10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNMT1 is perturbed and ATP10D expression is observed. Does this perturbation lead to a significant difference in ATP10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100653
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DNM1L and monitor MRPS27 expression. Decide whether this perturbation leads to a significant alteration in MRPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNM1L and monitor MRPS27 expression. Decide whether this perturbation leads to a significant alteration in MRPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39568
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPRTN is perturbed and VPS37A expression is quantified. Does this perturbation result in a significant change in VPS37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPRTN is perturbed and VPS37A expression is quantified. Does this perturbation result in a significant change in VPS37A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25302
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HAUS6 is perturbed and ZFR expression is observed. Does this perturbation lead to a significant difference in ZFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HAUS6 is perturbed and ZFR expression is observed. Does this perturbation lead to a significant difference in ZFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64533
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PMPCB is perturbed and CPE expression is quantified. Does this perturbation result in a significant change in CPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PMPCB is perturbed and CPE expression is quantified. Does this perturbation result in a significant change in CPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59462
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNASEH2C is perturbed and PPP1R9B expression is measured. Determine whether PPP1R9B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNASEH2C is perturbed and PPP1R9B expression is measured. Determine whether PPP1R9B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41659
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YTHDC1 and then measure expression of ZFP62. Does this perturbation cause a significant change in ZFP62 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YTHDC1 and then measure expression of ZFP62. Does this perturbation cause a significant change in ZFP62 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32604
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in THSD4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in THSD4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44555
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEPCE is perturbed and ANAPC1 expression is measured. Determine whether ANAPC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEPCE is perturbed and ANAPC1 expression is measured. Determine whether ANAPC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109359
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LPIN1 is perturbed and the expression of MRPL41 is measured. Determine whether MRPL41 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LPIN1 is perturbed and the expression of MRPL41 is measured. Determine whether MRPL41 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80256
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL7L1, does the expression profile of GBE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPL7L1, does the expression profile of GBE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45067
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KARS is associated with a significant change in RBMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KARS is associated with a significant change in RBMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4615
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARPC4 is perturbed and the expression of RILPL1 is measured. Determine whether RILPL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARPC4 is perturbed and the expression of RILPL1 is measured. Determine whether RILPL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20146
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PEX1 is perturbed and UBFD1 expression is quantified. Does this perturbation result in a significant change in UBFD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PEX1 is perturbed and UBFD1 expression is quantified. Does this perturbation result in a significant change in UBFD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121792
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NUDT15 is perturbed and NOP56 expression is quantified. Does this perturbation result in a significant change in NOP56 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NUDT15 is perturbed and NOP56 expression is quantified. Does this perturbation result in a significant change in NOP56 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28302
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDTC1, does the expression profile of ATXN7L3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of WDTC1, does the expression profile of ATXN7L3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3137
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRCC6 is associated with a significant change in CREBBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRCC6 is associated with a significant change in CREBBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102945
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS29 is perturbed and SGK1 expression is measured. Determine whether SGK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS29 is perturbed and SGK1 expression is measured. Determine whether SGK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67399
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP53RK is associated with a significant change in NGLY1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP53RK is associated with a significant change in NGLY1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14725
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNF168 is perturbed and NOVA1 expression is measured. Determine whether NOVA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RNF168 is perturbed and NOVA1 expression is measured. Determine whether NOVA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100929
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS16 is perturbed and the expression of GCFC2 is measured. Does this perturbation cause a significant change in GCFC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS16 is perturbed and the expression of GCFC2 is measured. Does this perturbation cause a significant change in GCFC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16650
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GOLT1B and examine the expression of MGST1. Does perturbing GOLT1B lead to a significant change in MGST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GOLT1B and examine the expression of MGST1. Does perturbing GOLT1B lead to a significant change in MGST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72501
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF12 is perturbed and the expression of ITCH is measured. Does this perturbation cause a significant change in ITCH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TAF12 is perturbed and the expression of ITCH is measured. Does this perturbation cause a significant change in ITCH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6820
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PKM and then measure expression of ERG28. Does this perturbation cause a significant change in ERG28 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PKM and then measure expression of ERG28. Does this perturbation cause a significant change in ERG28 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43884
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LTBP4 and then measure expression of SUN2. Does this perturbation cause a significant change in SUN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LTBP4 and then measure expression of SUN2. Does this perturbation cause a significant change in SUN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6064
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPTLC1 and monitor PRKD3 expression. Decide whether this perturbation leads to a significant alteration in PRKD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPTLC1 and monitor PRKD3 expression. Decide whether this perturbation leads to a significant alteration in PRKD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120298
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ILF2 and examine the expression of ZNF581. Does perturbing ILF2 lead to a significant change in ZNF581 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ILF2 and examine the expression of ZNF581. Does perturbing ILF2 lead to a significant change in ZNF581 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40271
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED16 and then measure expression of TMEM109. Does this perturbation cause a significant change in TMEM109 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MED16 and then measure expression of TMEM109. Does this perturbation cause a significant change in TMEM109 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110304
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM7 is perturbed and the expression of SCAMP2 is measured. Does this perturbation cause a significant change in SCAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM7 is perturbed and the expression of SCAMP2 is measured. Does this perturbation cause a significant change in SCAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93170
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELAC2 and then measure expression of MCL1. Does this perturbation cause a significant change in MCL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELAC2 and then measure expression of MCL1. Does this perturbation cause a significant change in MCL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56394
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PAXBP1 is perturbed and the expression of POLR2K is measured. Does this perturbation cause a significant change in POLR2K expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PAXBP1 is perturbed and the expression of POLR2K is measured. Does this perturbation cause a significant change in POLR2K expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35870
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT6A and examine the expression of TENT5A. Does perturbing CCT6A lead to a significant change in TENT5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCT6A and examine the expression of TENT5A. Does perturbing CCT6A lead to a significant change in TENT5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119271
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MLLT6, does the expression profile of DENND6A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MLLT6, does the expression profile of DENND6A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40677
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DCTN5 is perturbed and LINC00472 expression is observed. Does this perturbation lead to a significant difference in LINC00472 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DCTN5 is perturbed and LINC00472 expression is observed. Does this perturbation lead to a significant difference in LINC00472 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3713
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX23 and examine the expression of NUS1. Does perturbing DDX23 lead to a significant change in NUS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDX23 and examine the expression of NUS1. Does perturbing DDX23 lead to a significant change in NUS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45491
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DROSHA is perturbed and ITPRIPL2 expression is measured. Determine whether ITPRIPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DROSHA is perturbed and ITPRIPL2 expression is measured. Determine whether ITPRIPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102429
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL33 and then measure expression of SPPL2A. Does this perturbation cause a significant change in SPPL2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL33 and then measure expression of SPPL2A. Does this perturbation cause a significant change in SPPL2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81334
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD8 is associated with a significant change in ACOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD8 is associated with a significant change in ACOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60305
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3B is perturbed and the expression of ALKBH7 is measured. Does this perturbation cause a significant change in ALKBH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3B is perturbed and the expression of ALKBH7 is measured. Does this perturbation cause a significant change in ALKBH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111860
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM42 and examine the expression of SESN1. Does perturbing RBM42 lead to a significant change in SESN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM42 and examine the expression of SESN1. Does perturbing RBM42 lead to a significant change in SESN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68511
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOSC8, does the expression profile of AC008969.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EXOSC8, does the expression profile of AC008969.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115577
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRF1 is associated with a significant change in TARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRF1 is associated with a significant change in TARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7925
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PXN is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PXN is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48652
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATF5 is perturbed and RARS2 expression is quantified. Does this perturbation result in a significant change in RARS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATF5 is perturbed and RARS2 expression is quantified. Does this perturbation result in a significant change in RARS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75382
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UMPS is perturbed and UBAP2L expression is quantified. Does this perturbation result in a significant change in UBAP2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UMPS is perturbed and UBAP2L expression is quantified. Does this perturbation result in a significant change in UBAP2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94822
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GGPS1 is perturbed and the expression of GATAD2B is measured. Determine whether GATAD2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GGPS1 is perturbed and the expression of GATAD2B is measured. Determine whether GATAD2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86936
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ANAPC10 is perturbed and the expression of LNPEP is measured. Does this perturbation cause a significant change in LNPEP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ANAPC10 is perturbed and the expression of LNPEP is measured. Does this perturbation cause a significant change in LNPEP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57260
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TCERG1 is perturbed and the expression of TUBE1 is measured. Determine whether TUBE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TCERG1 is perturbed and the expression of TUBE1 is measured. Determine whether TUBE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40146
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2CB and then measure expression of ATXN7. Does this perturbation cause a significant change in ATXN7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPP2CB and then measure expression of ATXN7. Does this perturbation cause a significant change in ATXN7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10134
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MLST8 is perturbed and the expression of ZNF749 is measured. Determine whether ZNF749 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MLST8 is perturbed and the expression of ZNF749 is measured. Determine whether ZNF749 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52646
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNRNP40 and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNRNP40 and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47818
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TOP3A, does the expression profile of HABP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TOP3A, does the expression profile of HABP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103497
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFAB1 and then measure expression of ZFP90. Does this perturbation cause a significant change in ZFP90 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NDUFAB1 and then measure expression of ZFP90. Does this perturbation cause a significant change in ZFP90 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42414
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS3 and then measure expression of GPANK1. Does this perturbation cause a significant change in GPANK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPS3 and then measure expression of GPANK1. Does this perturbation cause a significant change in GPANK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117104
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNLL2 and examine the expression of GPN2. Does perturbing DYNLL2 lead to a significant change in GPN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNLL2 and examine the expression of GPN2. Does perturbing DYNLL2 lead to a significant change in GPN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69281
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3J and then measure expression of NCBP2AS2. Does this perturbation cause a significant change in NCBP2AS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3J and then measure expression of NCBP2AS2. Does this perturbation cause a significant change in NCBP2AS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12244
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BRK1 and monitor PSD3 expression. Decide whether this perturbation leads to a significant alteration in PSD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BRK1 and monitor PSD3 expression. Decide whether this perturbation leads to a significant alteration in PSD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71858
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR61 is associated with a significant change in MEST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR61 is associated with a significant change in MEST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86345
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF2BP2 is perturbed and CNOT6 expression is measured. Determine whether CNOT6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF2BP2 is perturbed and CNOT6 expression is measured. Determine whether CNOT6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95619
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFA2 is perturbed and the expression of SIAH2 is measured. Determine whether SIAH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFA2 is perturbed and the expression of SIAH2 is measured. Determine whether SIAH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17516
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK1 is perturbed and the expression of SCMH1 is measured. Does this perturbation cause a significant change in SCMH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK1 is perturbed and the expression of SCMH1 is measured. Does this perturbation cause a significant change in SCMH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99270
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIER1, does the expression profile of ACY1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIER1, does the expression profile of ACY1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26687
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOL8 is perturbed and TNFRSF10D expression is observed. Does this perturbation lead to a significant difference in TNFRSF10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NOL8 is perturbed and TNFRSF10D expression is observed. Does this perturbation lead to a significant difference in TNFRSF10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34693
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of NOL4L. Does this perturbation cause a significant change in NOL4L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of NOL4L. Does this perturbation cause a significant change in NOL4L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11524
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLR2B is perturbed and UHMK1 expression is observed. Does this perturbation lead to a significant difference in UHMK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLR2B is perturbed and UHMK1 expression is observed. Does this perturbation lead to a significant difference in UHMK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36523
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SARNP and monitor BEND6 expression. Decide whether this perturbation leads to a significant alteration in BEND6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARNP and monitor BEND6 expression. Decide whether this perturbation leads to a significant alteration in BEND6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99148
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIER1 is perturbed and CPA4 expression is quantified. Does this perturbation result in a significant change in CPA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIER1 is perturbed and CPA4 expression is quantified. Does this perturbation result in a significant change in CPA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26712
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PGAM1 is perturbed and PIR expression is quantified. Does this perturbation result in a significant change in PIR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PGAM1 is perturbed and PIR expression is quantified. Does this perturbation result in a significant change in PIR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106552
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FAU is perturbed and LRRC27 expression is observed. Does this perturbation lead to a significant difference in LRRC27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FAU is perturbed and LRRC27 expression is observed. Does this perturbation lead to a significant difference in LRRC27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34103
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SF3B2 is perturbed and the expression of ZNF24 is measured. Does this perturbation cause a significant change in ZNF24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SF3B2 is perturbed and the expression of ZNF24 is measured. Does this perturbation cause a significant change in ZNF24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121770
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRPF40A and then measure expression of SEC24A. Does this perturbation cause a significant change in SEC24A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRPF40A and then measure expression of SEC24A. Does this perturbation cause a significant change in SEC24A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113564
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of EEF1AKNMT is measured. Does this perturbation cause a significant change in EEF1AKNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of EEF1AKNMT is measured. Does this perturbation cause a significant change in EEF1AKNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20760
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YY1 is perturbed and the expression of TST is measured. Does this perturbation cause a significant change in TST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YY1 is perturbed and the expression of TST is measured. Does this perturbation cause a significant change in TST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60240
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMC3 and monitor HDAC9 expression. Decide whether this perturbation leads to a significant alteration in HDAC9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMC3 and monitor HDAC9 expression. Decide whether this perturbation leads to a significant alteration in HDAC9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41478
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BARD1 and monitor PRUNE2 expression. Decide whether this perturbation leads to a significant alteration in PRUNE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BARD1 and monitor PRUNE2 expression. Decide whether this perturbation leads to a significant alteration in PRUNE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122858
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TOP3A is perturbed and the expression of NDUFS1 is measured. Does this perturbation cause a significant change in NDUFS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TOP3A is perturbed and the expression of NDUFS1 is measured. Does this perturbation cause a significant change in NDUFS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103530
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5PD is perturbed and the expression of WDR12 is measured. Does this perturbation cause a significant change in WDR12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5PD is perturbed and the expression of WDR12 is measured. Does this perturbation cause a significant change in WDR12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69620
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NPLOC4 and examine the expression of TTLL7. Does perturbing NPLOC4 lead to a significant change in TTLL7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NPLOC4 and examine the expression of TTLL7. Does perturbing NPLOC4 lead to a significant change in TTLL7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17861
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AHCTF1 and monitor ATF4 expression. Decide whether this perturbation leads to a significant alteration in ATF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AHCTF1 and monitor ATF4 expression. Decide whether this perturbation leads to a significant alteration in ATF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69708
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ACIN1 is perturbed and ALS2 expression is quantified. Does this perturbation result in a significant change in ALS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ACIN1 is perturbed and ALS2 expression is quantified. Does this perturbation result in a significant change in ALS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20712
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALG2, does the expression profile of ZNF107 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ALG2, does the expression profile of ZNF107 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1817
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UTP25 is perturbed and ARHGAP1 expression is observed. Does this perturbation lead to a significant difference in ARHGAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UTP25 is perturbed and ARHGAP1 expression is observed. Does this perturbation lead to a significant difference in ARHGAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54083
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSNK2B is perturbed and the expression of SPSB3 is measured. Determine whether SPSB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSNK2B is perturbed and the expression of SPSB3 is measured. Determine whether SPSB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44156
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS17 is perturbed and MSH2 expression is measured. Determine whether MSH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS17 is perturbed and MSH2 expression is measured. Determine whether MSH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17179
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BTAF1 is perturbed and PCM1 expression is quantified. Does this perturbation result in a significant change in PCM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BTAF1 is perturbed and PCM1 expression is quantified. Does this perturbation result in a significant change in PCM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67832
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSBP and monitor COPS5 expression. Decide whether this perturbation leads to a significant alteration in COPS5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSBP and monitor COPS5 expression. Decide whether this perturbation leads to a significant alteration in COPS5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96348
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP1CA and examine the expression of RPL17. Does perturbing PPP1CA lead to a significant change in RPL17 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP1CA and examine the expression of RPL17. Does perturbing PPP1CA lead to a significant change in RPL17 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40791
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDC27 is perturbed and TFAP2A expression is observed. Does this perturbation lead to a significant difference in TFAP2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDC27 is perturbed and TFAP2A expression is observed. Does this perturbation lead to a significant difference in TFAP2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14803
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS35 is perturbed and GABARAPL1 expression is measured. Determine whether GABARAPL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, VPS35 is perturbed and GABARAPL1 expression is measured. Determine whether GABARAPL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":499
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS9 and examine the expression of GID4. Does perturbing MRPS9 lead to a significant change in GID4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS9 and examine the expression of GID4. Does perturbing MRPS9 lead to a significant change in GID4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34301
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS18C, does the expression profile of LRRC75A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS18C, does the expression profile of LRRC75A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112147
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MYCBP, does the expression profile of SGK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MYCBP, does the expression profile of SGK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90607
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL34 is perturbed and PCDH10 expression is observed. Does this perturbation lead to a significant difference in PCDH10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL34 is perturbed and PCDH10 expression is observed. Does this perturbation lead to a significant difference in PCDH10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10283
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PCBP1 is perturbed and ZCCHC7 expression is observed. Does this perturbation lead to a significant difference in ZCCHC7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PCBP1 is perturbed and ZCCHC7 expression is observed. Does this perturbation lead to a significant difference in ZCCHC7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25453
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ADRM1 is perturbed and ZNF503 expression is observed. Does this perturbation lead to a significant difference in ZNF503 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ADRM1 is perturbed and ZNF503 expression is observed. Does this perturbation lead to a significant difference in ZNF503 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1553
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCMBP is perturbed and AFDN expression is measured. Determine whether AFDN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MCMBP is perturbed and AFDN expression is measured. Determine whether AFDN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17639
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL54 is perturbed and the expression of GMPS is measured. Does this perturbation cause a significant change in GMPS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL54 is perturbed and the expression of GMPS is measured. Does this perturbation cause a significant change in GMPS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40540
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS5 is perturbed and ATP2C1 expression is quantified. Does this perturbation result in a significant change in ATP2C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS5 is perturbed and ATP2C1 expression is quantified. Does this perturbation result in a significant change in ATP2C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89062
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAA38 and then measure expression of USP3. Does this perturbation cause a significant change in USP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NAA38 and then measure expression of USP3. Does this perturbation cause a significant change in USP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13024
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRPF31 is perturbed and the expression of POLR2C is measured. Does this perturbation cause a significant change in POLR2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRPF31 is perturbed and the expression of POLR2C is measured. Does this perturbation cause a significant change in POLR2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25980
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3C3 is perturbed and JMJD1C expression is quantified. Does this perturbation result in a significant change in JMJD1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GTF3C3 is perturbed and JMJD1C expression is quantified. Does this perturbation result in a significant change in JMJD1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73262
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNL3L is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNL3L is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114665
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GIT2, does the expression profile of GSE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GIT2, does the expression profile of GSE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27157
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CTPS1 and examine the expression of MALAT1. Does perturbing CTPS1 lead to a significant change in MALAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CTPS1 and examine the expression of MALAT1. Does perturbing CTPS1 lead to a significant change in MALAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122011
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KAT7 is perturbed and the expression of KHNYN is measured. Does this perturbation cause a significant change in KHNYN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KAT7 is perturbed and the expression of KHNYN is measured. Does this perturbation cause a significant change in KHNYN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84690
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMG7 is associated with a significant change in USP53 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMG7 is associated with a significant change in USP53 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77545
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP6V0C and monitor NNMT expression. Decide whether this perturbation leads to a significant alteration in NNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP6V0C and monitor NNMT expression. Decide whether this perturbation leads to a significant alteration in NNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42588
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD8 and monitor CDK5 expression. Decide whether this perturbation leads to a significant alteration in CDK5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD8 and monitor CDK5 expression. Decide whether this perturbation leads to a significant alteration in CDK5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60348
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYS1 and then measure expression of AASDH. Does this perturbation cause a significant change in AASDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYS1 and then measure expression of AASDH. Does this perturbation cause a significant change in AASDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20044
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF3, does the expression profile of PPP1R10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CPSF3, does the expression profile of PPP1R10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8087
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF236 is perturbed and CHMP7 expression is measured. Determine whether CHMP7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF236 is perturbed and CHMP7 expression is measured. Determine whether CHMP7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79419
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GINS4 and then measure expression of C16orf91. Does this perturbation cause a significant change in C16orf91 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GINS4 and then measure expression of C16orf91. Does this perturbation cause a significant change in C16orf91 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37424
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LSM2 is perturbed and KIAA1549L expression is measured. Determine whether KIAA1549L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LSM2 is perturbed and KIAA1549L expression is measured. Determine whether KIAA1549L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48869
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR36 is perturbed and the expression of PIGT is measured. Does this perturbation cause a significant change in PIGT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR36 is perturbed and the expression of PIGT is measured. Does this perturbation cause a significant change in PIGT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90900
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYF2 is perturbed and the expression of CDC40 is measured. Does this perturbation cause a significant change in CDC40 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYF2 is perturbed and the expression of CDC40 is measured. Does this perturbation cause a significant change in CDC40 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24460
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NOP56 and monitor USP6NL expression. Decide whether this perturbation leads to a significant alteration in USP6NL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NOP56 and monitor USP6NL expression. Decide whether this perturbation leads to a significant alteration in USP6NL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15718
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DICER1 and examine the expression of PPP1R37. Does perturbing DICER1 lead to a significant change in PPP1R37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DICER1 and examine the expression of PPP1R37. Does perturbing DICER1 lead to a significant change in PPP1R37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77791
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SIN3A and examine the expression of ENTPD7. Does perturbing SIN3A lead to a significant change in ENTPD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SIN3A and examine the expression of ENTPD7. Does perturbing SIN3A lead to a significant change in ENTPD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73071
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL11 and then measure expression of GIT1. Does this perturbation cause a significant change in GIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL11 and then measure expression of GIT1. Does this perturbation cause a significant change in GIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63864
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NEPRO and monitor CNOT3 expression. Decide whether this perturbation leads to a significant alteration in CNOT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEPRO and monitor CNOT3 expression. Decide whether this perturbation leads to a significant alteration in CNOT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107928
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX52 is perturbed and the expression of CREBL2 is measured. Does this perturbation cause a significant change in CREBL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDX52 is perturbed and the expression of CREBL2 is measured. Does this perturbation cause a significant change in CREBL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105770
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC10 and then measure expression of HPS1. Does this perturbation cause a significant change in HPS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EXOSC10 and then measure expression of HPS1. Does this perturbation cause a significant change in HPS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56544
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SMC6 and monitor THAP1 expression. Decide whether this perturbation leads to a significant alteration in THAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SMC6 and monitor THAP1 expression. Decide whether this perturbation leads to a significant alteration in THAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95688
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NPM3 and then measure expression of AKIP1. Does this perturbation cause a significant change in AKIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NPM3 and then measure expression of AKIP1. Does this perturbation cause a significant change in AKIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19284
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CMTR2 is perturbed and ARHGEF9 expression is measured. Determine whether ARHGEF9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CMTR2 is perturbed and ARHGEF9 expression is measured. Determine whether ARHGEF9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112999
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGLN2 is perturbed and the expression of TAF9B is measured. Does this perturbation cause a significant change in TAF9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGLN2 is perturbed and the expression of TAF9B is measured. Does this perturbation cause a significant change in TAF9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20640
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC7A5 and then measure expression of SLC2A11. Does this perturbation cause a significant change in SLC2A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC7A5 and then measure expression of SLC2A11. Does this perturbation cause a significant change in SLC2A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28914
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPEN and examine the expression of UBE2W. Does perturbing SPEN lead to a significant change in UBE2W expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPEN and examine the expression of UBE2W. Does perturbing SPEN lead to a significant change in UBE2W expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94681
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SERBP1 and monitor TPST1 expression. Decide whether this perturbation leads to a significant alteration in TPST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SERBP1 and monitor TPST1 expression. Decide whether this perturbation leads to a significant alteration in TPST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1408
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf53 is perturbed and the expression of TUSC2 is measured. Does this perturbation cause a significant change in TUSC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf53 is perturbed and the expression of TUSC2 is measured. Does this perturbation cause a significant change in TUSC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79090
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RBM25 and monitor FIG4 expression. Decide whether this perturbation leads to a significant alteration in FIG4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RBM25 and monitor FIG4 expression. Decide whether this perturbation leads to a significant alteration in FIG4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29788
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KCTD10 and monitor ADAMTS1 expression. Decide whether this perturbation leads to a significant alteration in ADAMTS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KCTD10 and monitor ADAMTS1 expression. Decide whether this perturbation leads to a significant alteration in ADAMTS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70868
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C5orf30 is perturbed and GATA6 expression is quantified. Does this perturbation result in a significant change in GATA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C5orf30 is perturbed and GATA6 expression is quantified. Does this perturbation result in a significant change in GATA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47972
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS17, does the expression profile of HSD17B10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS17, does the expression profile of HSD17B10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92437
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WEE1 and examine the expression of CCDC82. Does perturbing WEE1 lead to a significant change in CCDC82 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WEE1 and examine the expression of CCDC82. Does perturbing WEE1 lead to a significant change in CCDC82 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66121
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACIN1, does the expression profile of SETD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ACIN1, does the expression profile of SETD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20757
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MCM4 and examine the expression of RANBP6. Does perturbing MCM4 lead to a significant change in RANBP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MCM4 and examine the expression of RANBP6. Does perturbing MCM4 lead to a significant change in RANBP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106981
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS31, does the expression profile of CYB5R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPS31, does the expression profile of CYB5R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS31 is perturbed and RNF41 expression is measured. Determine whether RNF41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPS31 is perturbed and RNF41 expression is measured. Determine whether RNF41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DTL and monitor MAPKAPK5-AS1 expression. Decide whether this perturbation leads to a significant alteration in MAPKAPK5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DTL and monitor MAPKAPK5-AS1 expression. Decide whether this perturbation leads to a significant alteration in MAPKAPK5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88688
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FGFR1OP is perturbed and POC1B expression is quantified. Does this perturbation result in a significant change in POC1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FGFR1OP is perturbed and POC1B expression is quantified. Does this perturbation result in a significant change in POC1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95502
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POLR3A and monitor AP3S2 expression. Decide whether this perturbation leads to a significant alteration in AP3S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POLR3A and monitor AP3S2 expression. Decide whether this perturbation leads to a significant alteration in AP3S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94168
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3M, does the expression profile of SNHG19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3M, does the expression profile of SNHG19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39967
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRF and examine the expression of SEC62. Does perturbing SRF lead to a significant change in SEC62 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRF and examine the expression of SEC62. Does perturbing SRF lead to a significant change in SEC62 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85101
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAM207A, does the expression profile of C1RL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAM207A, does the expression profile of C1RL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18117
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BRCA1 is perturbed and AL627171.2 expression is observed. Does this perturbation lead to a significant difference in AL627171.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BRCA1 is perturbed and AL627171.2 expression is observed. Does this perturbation lead to a significant difference in AL627171.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121713
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF4E, does the expression profile of FBXW4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF4E, does the expression profile of FBXW4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7367
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD11, does the expression profile of NXPE3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD11, does the expression profile of NXPE3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94867
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COQ4 is associated with a significant change in SNHG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COQ4 is associated with a significant change in SNHG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119215
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STX18 is associated with a significant change in EIF2B5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STX18 is associated with a significant change in EIF2B5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30675
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BDP1 and then measure expression of ARRDC1. Does this perturbation cause a significant change in ARRDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BDP1 and then measure expression of ARRDC1. Does this perturbation cause a significant change in ARRDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49404
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MVD is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MVD is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67432
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GTPBP4 is perturbed and the expression of WRAP73 is measured. Does this perturbation cause a significant change in WRAP73 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GTPBP4 is perturbed and the expression of WRAP73 is measured. Does this perturbation cause a significant change in WRAP73 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53830
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEF2 and examine the expression of BTBD1. Does perturbing EEF2 lead to a significant change in BTBD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EEF2 and examine the expression of BTBD1. Does perturbing EEF2 lead to a significant change in BTBD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36421
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZCCHC9 is associated with a significant change in TIMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZCCHC9 is associated with a significant change in TIMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78665
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COG6 is perturbed and PBX1 expression is observed. Does this perturbation lead to a significant difference in PBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COG6 is perturbed and PBX1 expression is observed. Does this perturbation lead to a significant difference in PBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25733
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGAM1 and examine the expression of UXT. Does perturbing PGAM1 lead to a significant change in UXT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGAM1 and examine the expression of UXT. Does perturbing PGAM1 lead to a significant change in UXT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106581
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZFR and examine the expression of ANAPC4. Does perturbing ZFR lead to a significant change in ANAPC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZFR and examine the expression of ANAPC4. Does perturbing ZFR lead to a significant change in ANAPC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65301
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF1D and examine the expression of PIK3C3. Does perturbing TAF1D lead to a significant change in PIK3C3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF1D and examine the expression of PIK3C3. Does perturbing TAF1D lead to a significant change in PIK3C3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94191
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UQCRC2 is associated with a significant change in TGFBR3L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UQCRC2 is associated with a significant change in TGFBR3L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96485
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LRR1 and monitor PEX26 expression. Decide whether this perturbation leads to a significant alteration in PEX26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LRR1 and monitor PEX26 expression. Decide whether this perturbation leads to a significant alteration in PEX26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102188
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS2 is associated with a significant change in TJAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS2 is associated with a significant change in TJAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63465
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAMAC is associated with a significant change in ANKRD12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RAMAC is associated with a significant change in ANKRD12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94635
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL39 and examine the expression of EIF1B. Does perturbing RPL39 lead to a significant change in EIF1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RPL39 and examine the expression of EIF1B. Does perturbing RPL39 lead to a significant change in EIF1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37101
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, WTAP is perturbed and the expression of TRIM8 is measured. Does this perturbation cause a significant change in TRIM8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, WTAP is perturbed and the expression of TRIM8 is measured. Does this perturbation cause a significant change in TRIM8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41750
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and SELENON expression is observed. Does this perturbation lead to a significant difference in SELENON expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and SELENON expression is observed. Does this perturbation lead to a significant difference in SELENON expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95313
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OGT is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OGT is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112269
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LARS is perturbed and the expression of RNF187 is measured. Determine whether RNF187 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LARS is perturbed and the expression of RNF187 is measured. Determine whether RNF187 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86886
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL32 is associated with a significant change in TGFBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL32 is associated with a significant change in TGFBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17355
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF5 and examine the expression of REEP5. Does perturbing TAF5 lead to a significant change in REEP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF5 and examine the expression of REEP5. Does perturbing TAF5 lead to a significant change in REEP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62651
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BANP and then measure expression of ZSCAN16-AS1. Does this perturbation cause a significant change in ZSCAN16-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BANP and then measure expression of ZSCAN16-AS1. Does this perturbation cause a significant change in ZSCAN16-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121014
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLSPN is associated with a significant change in RND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLSPN is associated with a significant change in RND3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122465
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMB6 is perturbed and the expression of NAV3 is measured. Does this perturbation cause a significant change in NAV3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMB6 is perturbed and the expression of NAV3 is measured. Does this perturbation cause a significant change in NAV3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63800
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SURF6 and monitor CDKN2B expression. Decide whether this perturbation leads to a significant alteration in CDKN2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SURF6 and monitor CDKN2B expression. Decide whether this perturbation leads to a significant alteration in CDKN2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35178
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBPL1 and monitor CCDC174 expression. Decide whether this perturbation leads to a significant alteration in CCDC174 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBPL1 and monitor CCDC174 expression. Decide whether this perturbation leads to a significant alteration in CCDC174 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45438
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFA2 is perturbed and CEP85L expression is measured. Determine whether CEP85L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFA2 is perturbed and CEP85L expression is measured. Determine whether CEP85L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17499
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCAPH2 and examine the expression of GDE1. Does perturbing NCAPH2 lead to a significant change in GDE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCAPH2 and examine the expression of GDE1. Does perturbing NCAPH2 lead to a significant change in GDE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112331
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GEMIN5 is perturbed and ARPC4 expression is measured. Determine whether ARPC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GEMIN5 is perturbed and ARPC4 expression is measured. Determine whether ARPC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49159
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CENPI and then measure expression of HEXIM1. Does this perturbation cause a significant change in HEXIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CENPI and then measure expression of HEXIM1. Does this perturbation cause a significant change in HEXIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57334
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS12 and examine the expression of C1GALT1C1. Does perturbing INTS12 lead to a significant change in C1GALT1C1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb INTS12 and examine the expression of C1GALT1C1. Does perturbing INTS12 lead to a significant change in C1GALT1C1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89141
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ERCC2 is perturbed and the expression of SNX3 is measured. Determine whether SNX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ERCC2 is perturbed and the expression of SNX3 is measured. Determine whether SNX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74436
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPC and then measure expression of XPNPEP1. Does this perturbation cause a significant change in XPNPEP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNRNPC and then measure expression of XPNPEP1. Does this perturbation cause a significant change in XPNPEP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110144
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TXNL4A is perturbed and C7orf26 expression is observed. Does this perturbation lead to a significant difference in C7orf26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TXNL4A is perturbed and C7orf26 expression is observed. Does this perturbation lead to a significant difference in C7orf26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84323
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSEN54 and examine the expression of JUND. Does perturbing TSEN54 lead to a significant change in JUND expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSEN54 and examine the expression of JUND. Does perturbing TSEN54 lead to a significant change in JUND expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88751
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFB6 is perturbed and RETSAT expression is measured. Determine whether RETSAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFB6 is perturbed and RETSAT expression is measured. Determine whether RETSAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65919
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHMP2A is perturbed and TMEM132A expression is observed. Does this perturbation lead to a significant difference in TMEM132A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHMP2A is perturbed and TMEM132A expression is observed. Does this perturbation lead to a significant difference in TMEM132A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121563
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ABCE1 is perturbed and RASAL2 expression is measured. Determine whether RASAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ABCE1 is perturbed and RASAL2 expression is measured. Determine whether RASAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65759
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAMM41 is perturbed and the expression of MICU3 is measured. Determine whether MICU3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAMM41 is perturbed and the expression of MICU3 is measured. Determine whether MICU3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95726
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3D, does the expression profile of ABI1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3D, does the expression profile of ABI1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49227
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC5 is perturbed and INSIG1 expression is observed. Does this perturbation lead to a significant difference in INSIG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EXOC5 is perturbed and INSIG1 expression is observed. Does this perturbation lead to a significant difference in INSIG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102473
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR26 and examine the expression of NCOR1. Does perturbing WDR26 lead to a significant change in NCOR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR26 and examine the expression of NCOR1. Does perturbing WDR26 lead to a significant change in NCOR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23801
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL28 is perturbed and C9orf16 expression is observed. Does this perturbation lead to a significant difference in C9orf16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL28 is perturbed and C9orf16 expression is observed. Does this perturbation lead to a significant difference in C9orf16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39793
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMA3 and then measure expression of ATP6V1A. Does this perturbation cause a significant change in ATP6V1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMA3 and then measure expression of ATP6V1A. Does this perturbation cause a significant change in ATP6V1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22894
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPZ is perturbed and the expression of PCBD2 is measured. Does this perturbation cause a significant change in PCBD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPZ is perturbed and the expression of PCBD2 is measured. Does this perturbation cause a significant change in PCBD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91040
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb INTS3 and monitor GNPDA1 expression. Decide whether this perturbation leads to a significant alteration in GNPDA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb INTS3 and monitor GNPDA1 expression. Decide whether this perturbation leads to a significant alteration in GNPDA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5718
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb WDHD1 and monitor MMAB expression. Decide whether this perturbation leads to a significant alteration in MMAB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb WDHD1 and monitor MMAB expression. Decide whether this perturbation leads to a significant alteration in MMAB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96618
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PGAM5 is perturbed and the expression of ZBTB40 is measured. Does this perturbation cause a significant change in ZBTB40 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PGAM5 is perturbed and the expression of ZBTB40 is measured. Does this perturbation cause a significant change in ZBTB40 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1190
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZW10 is perturbed and NOM1 expression is observed. Does this perturbation lead to a significant difference in NOM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZW10 is perturbed and NOM1 expression is observed. Does this perturbation lead to a significant difference in NOM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44303
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMU1, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SMU1, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48597
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLD1 is associated with a significant change in WBP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLD1 is associated with a significant change in WBP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14635
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL21 and then measure expression of AGPAT5. Does this perturbation cause a significant change in AGPAT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL21 and then measure expression of AGPAT5. Does this perturbation cause a significant change in AGPAT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92754
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PDHA1 and monitor SPOP expression. Decide whether this perturbation leads to a significant alteration in SPOP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDHA1 and monitor SPOP expression. Decide whether this perturbation leads to a significant alteration in SPOP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104418
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LAMB1 is associated with a significant change in IFRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LAMB1 is associated with a significant change in IFRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55595
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL35 and monitor MT-ATP8 expression. Decide whether this perturbation leads to a significant alteration in MT-ATP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL35 and monitor MT-ATP8 expression. Decide whether this perturbation leads to a significant alteration in MT-ATP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7428
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF4H is perturbed and CD3EAP expression is quantified. Does this perturbation result in a significant change in CD3EAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF4H is perturbed and CD3EAP expression is quantified. Does this perturbation result in a significant change in CD3EAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4952
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of ANTXR2 is measured. Determine whether ANTXR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of ANTXR2 is measured. Determine whether ANTXR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37816
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ENO1, does the expression profile of TPST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ENO1, does the expression profile of TPST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29847
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COA5 is perturbed and THAP3 expression is quantified. Does this perturbation result in a significant change in THAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COA5 is perturbed and THAP3 expression is quantified. Does this perturbation result in a significant change in THAP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84482
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb VPS35 and monitor CA9 expression. Decide whether this perturbation leads to a significant alteration in CA9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb VPS35 and monitor CA9 expression. Decide whether this perturbation leads to a significant alteration in CA9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":518
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL45 and monitor RPL10 expression. Decide whether this perturbation leads to a significant alteration in RPL10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL45 and monitor RPL10 expression. Decide whether this perturbation leads to a significant alteration in RPL10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116928
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MBTPS2 is perturbed and CMTM3 expression is observed. Does this perturbation lead to a significant difference in CMTM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MBTPS2 is perturbed and CMTM3 expression is observed. Does this perturbation lead to a significant difference in CMTM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32553
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHX29 and examine the expression of ZNF143. Does perturbing DHX29 lead to a significant change in ZNF143 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHX29 and examine the expression of ZNF143. Does perturbing DHX29 lead to a significant change in ZNF143 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82771
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4G2 and then measure expression of TAMM41. Does this perturbation cause a significant change in TAMM41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4G2 and then measure expression of TAMM41. Does this perturbation cause a significant change in TAMM41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53484
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TWISTNB is associated with a significant change in C9orf16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TWISTNB is associated with a significant change in C9orf16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116765
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS6 is perturbed and the expression of SULF1 is measured. Determine whether SULF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS6 is perturbed and the expression of SULF1 is measured. Determine whether SULF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93236
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC1 is perturbed and HMGCR expression is measured. Determine whether HMGCR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOC1 is perturbed and HMGCR expression is measured. Determine whether HMGCR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99979
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR3 is perturbed and IFT20 expression is quantified. Does this perturbation result in a significant change in IFT20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WDR3 is perturbed and IFT20 expression is quantified. Does this perturbation result in a significant change in IFT20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79672
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CPSF4 and examine the expression of VCPIP1. Does perturbing CPSF4 lead to a significant change in VCPIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CPSF4 and examine the expression of VCPIP1. Does perturbing CPSF4 lead to a significant change in VCPIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111921
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM13 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM13 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92584
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, INO80 is perturbed and TRNP1 expression is measured. Determine whether TRNP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, INO80 is perturbed and TRNP1 expression is measured. Determine whether TRNP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108109
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSGEP and then measure expression of NR1D2. Does this perturbation cause a significant change in NR1D2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSGEP and then measure expression of NR1D2. Does this perturbation cause a significant change in NR1D2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51234
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AP2A1 is perturbed and the expression of TAX1BP3 is measured. Does this perturbation cause a significant change in TAX1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AP2A1 is perturbed and the expression of TAX1BP3 is measured. Does this perturbation cause a significant change in TAX1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96000
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LUC7L3 is perturbed and RCN2 expression is quantified. Does this perturbation result in a significant change in RCN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LUC7L3 is perturbed and RCN2 expression is quantified. Does this perturbation result in a significant change in RCN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15682
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUGT1, does the expression profile of VGLL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUGT1, does the expression profile of VGLL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113597
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR82 is perturbed and CD276 expression is measured. Determine whether CD276 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, WDR82 is perturbed and CD276 expression is measured. Determine whether CD276 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111199
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UTP18, does the expression profile of BORCS5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UTP18, does the expression profile of BORCS5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111637
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, INTS14 is perturbed and KRT80 expression is measured. Determine whether KRT80 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, INTS14 is perturbed and KRT80 expression is measured. Determine whether KRT80 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34589
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USPL1, does the expression profile of PHLDA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USPL1, does the expression profile of PHLDA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97277
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP1A1, does the expression profile of IGF2BP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP1A1, does the expression profile of IGF2BP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90077
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBPL1 is perturbed and PUS1 expression is observed. Does this perturbation lead to a significant difference in PUS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBPL1 is perturbed and PUS1 expression is observed. Does this perturbation lead to a significant difference in PUS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45423
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZW10 is associated with a significant change in NOM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZW10 is associated with a significant change in NOM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44305
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GABPA is perturbed and the expression of LYST is measured. Determine whether LYST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GABPA is perturbed and the expression of LYST is measured. Determine whether LYST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75706
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3F is perturbed and RXRB expression is observed. Does this perturbation lead to a significant difference in RXRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3F is perturbed and RXRB expression is observed. Does this perturbation lead to a significant difference in RXRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123523
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZWINT is associated with a significant change in MRPS10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZWINT is associated with a significant change in MRPS10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48965
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS9 is perturbed and the expression of SLC38A6 is measured. Determine whether SLC38A6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS9 is perturbed and the expression of SLC38A6 is measured. Determine whether SLC38A6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34326
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED14, does the expression profile of SLC25A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED14, does the expression profile of SLC25A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41427
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF1D is perturbed and PIK3C3 expression is measured. Determine whether PIK3C3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF1D is perturbed and PIK3C3 expression is measured. Determine whether PIK3C3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94199
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HMBOX1 and then measure expression of MED31. Does this perturbation cause a significant change in MED31 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HMBOX1 and then measure expression of MED31. Does this perturbation cause a significant change in MED31 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100044
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRKRA, does the expression profile of UBTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRKRA, does the expression profile of UBTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117297
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM9 and monitor PPP6R1 expression. Decide whether this perturbation leads to a significant alteration in PPP6R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM9 and monitor PPP6R1 expression. Decide whether this perturbation leads to a significant alteration in PPP6R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74308
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TFAM is perturbed and CA9 expression is measured. Determine whether CA9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TFAM is perturbed and CA9 expression is measured. Determine whether CA9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1259
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF4 is perturbed and RNF14 expression is quantified. Does this perturbation result in a significant change in RNF14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRPF4 is perturbed and RNF14 expression is quantified. Does this perturbation result in a significant change in RNF14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70372
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RAB18 is perturbed and NUTM2B-AS1 expression is observed. Does this perturbation lead to a significant difference in NUTM2B-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RAB18 is perturbed and NUTM2B-AS1 expression is observed. Does this perturbation lead to a significant difference in NUTM2B-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104853
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABCB7 and examine the expression of TGFB2. Does perturbing ABCB7 lead to a significant change in TGFB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABCB7 and examine the expression of TGFB2. Does perturbing ABCB7 lead to a significant change in TGFB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117871
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ANKS6 is perturbed and NFIA expression is quantified. Does this perturbation result in a significant change in NFIA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ANKS6 is perturbed and NFIA expression is quantified. Does this perturbation result in a significant change in NFIA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43582
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISG20L2 and then measure expression of UBQLN2. Does this perturbation cause a significant change in UBQLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISG20L2 and then measure expression of UBQLN2. Does this perturbation cause a significant change in UBQLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112794
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFS5, does the expression profile of ARL6IP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NDUFS5, does the expression profile of ARL6IP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2197
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDC45 is perturbed and TBC1D10B expression is quantified. Does this perturbation result in a significant change in TBC1D10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDC45 is perturbed and TBC1D10B expression is quantified. Does this perturbation result in a significant change in TBC1D10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117632
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3M is perturbed and PRPF3 expression is observed. Does this perturbation lead to a significant difference in PRPF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF3M is perturbed and PRPF3 expression is observed. Does this perturbation lead to a significant difference in PRPF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40013
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MCRS1 is perturbed and DDIT3 expression is observed. Does this perturbation lead to a significant difference in DDIT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MCRS1 is perturbed and DDIT3 expression is observed. Does this perturbation lead to a significant difference in DDIT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55263
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF3L and monitor TRERF1 expression. Decide whether this perturbation leads to a significant alteration in TRERF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF3L and monitor TRERF1 expression. Decide whether this perturbation leads to a significant alteration in TRERF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9438
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BUD31, does the expression profile of PDCD7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BUD31, does the expression profile of PDCD7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36597
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ILF2, does the expression profile of FUCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ILF2, does the expression profile of FUCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40317
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP37 is perturbed and SMURF2 expression is measured. Determine whether SMURF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, USP37 is perturbed and SMURF2 expression is measured. Determine whether SMURF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98579
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARIH1 is perturbed and the expression of IGHMBP2 is measured. Does this perturbation cause a significant change in IGHMBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARIH1 is perturbed and the expression of IGHMBP2 is measured. Does this perturbation cause a significant change in IGHMBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14170
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CS and then measure expression of SPRY2. Does this perturbation cause a significant change in SPRY2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CS and then measure expression of SPRY2. Does this perturbation cause a significant change in SPRY2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79044
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP1CB and examine the expression of LTBP3. Does perturbing PPP1CB lead to a significant change in LTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP1CB and examine the expression of LTBP3. Does perturbing PPP1CB lead to a significant change in LTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122531
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which URM1 is perturbed and DHTKD1 expression is observed. Does this perturbation lead to a significant difference in DHTKD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which URM1 is perturbed and DHTKD1 expression is observed. Does this perturbation lead to a significant difference in DHTKD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103603
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF5A is perturbed and CYB5R1 expression is quantified. Does this perturbation result in a significant change in CYB5R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF5A is perturbed and CYB5R1 expression is quantified. Does this perturbation result in a significant change in CYB5R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81792
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NUP214 and monitor LMO4 expression. Decide whether this perturbation leads to a significant alteration in LMO4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NUP214 and monitor LMO4 expression. Decide whether this perturbation leads to a significant alteration in LMO4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103738
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSEN34 and then measure expression of PIAS4. Does this perturbation cause a significant change in PIAS4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSEN34 and then measure expression of PIAS4. Does this perturbation cause a significant change in PIAS4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18994
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNOT11 is perturbed and the expression of ELMSAN1 is measured. Determine whether ELMSAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNOT11 is perturbed and the expression of ELMSAN1 is measured. Determine whether ELMSAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75446
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPP2CA is perturbed and SLC35G1 expression is observed. Does this perturbation lead to a significant difference in SLC35G1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPP2CA is perturbed and SLC35G1 expression is observed. Does this perturbation lead to a significant difference in SLC35G1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16443
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP5 is perturbed and GREM1 expression is quantified. Does this perturbation result in a significant change in GREM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHMP5 is perturbed and GREM1 expression is quantified. Does this perturbation result in a significant change in GREM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22242
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAST is perturbed and ABCD4 expression is measured. Determine whether ABCD4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAST is perturbed and ABCD4 expression is measured. Determine whether ABCD4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66569
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF1B and examine the expression of FAM162A. Does perturbing TAF1B lead to a significant change in FAM162A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TAF1B and examine the expression of FAM162A. Does perturbing TAF1B lead to a significant change in FAM162A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92101
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CXXC1 is perturbed and the expression of RAB30-DT is measured. Determine whether RAB30-DT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CXXC1 is perturbed and the expression of RAB30-DT is measured. Determine whether RAB30-DT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67636
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM13 is perturbed and HSPA4L expression is observed. Does this perturbation lead to a significant difference in HSPA4L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM13 is perturbed and HSPA4L expression is observed. Does this perturbation lead to a significant difference in HSPA4L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92613
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDC1 is perturbed and ING4 expression is measured. Determine whether ING4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDC1 is perturbed and ING4 expression is measured. Determine whether ING4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76869
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS12 is associated with a significant change in C1GALT1C1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of INTS12 is associated with a significant change in C1GALT1C1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89145
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4G2 is perturbed and the expression of PLEKHA3 is measured. Does this perturbation cause a significant change in PLEKHA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF4G2 is perturbed and the expression of PLEKHA3 is measured. Does this perturbation cause a significant change in PLEKHA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53450
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R15B is perturbed and the expression of DUSP22 is measured. Does this perturbation cause a significant change in DUSP22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R15B is perturbed and the expression of DUSP22 is measured. Does this perturbation cause a significant change in DUSP22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115120
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CPSF6 is perturbed and NFAT5 expression is observed. Does this perturbation lead to a significant difference in NFAT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CPSF6 is perturbed and NFAT5 expression is observed. Does this perturbation lead to a significant difference in NFAT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61073
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor SLC35B3 expression. Decide whether this perturbation leads to a significant alteration in SLC35B3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor SLC35B3 expression. Decide whether this perturbation leads to a significant alteration in SLC35B3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6168
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED21, does the expression profile of DOCK5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MED21, does the expression profile of DOCK5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123127
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNOT9 is perturbed and HLA-B expression is measured. Determine whether HLA-B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNOT9 is perturbed and HLA-B expression is measured. Determine whether HLA-B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113399
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SP2 is perturbed and the expression of RAB31 is measured. Does this perturbation cause a significant change in RAB31 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SP2 is perturbed and the expression of RAB31 is measured. Does this perturbation cause a significant change in RAB31 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73740
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CABIN1 and then measure expression of PMEPA1. Does this perturbation cause a significant change in PMEPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CABIN1 and then measure expression of PMEPA1. Does this perturbation cause a significant change in PMEPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39304
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD11 is associated with a significant change in HMOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ANKRD11 is associated with a significant change in HMOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65945
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDCD6IP, does the expression profile of EEF1E1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDCD6IP, does the expression profile of EEF1E1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10087
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR3 is perturbed and MT-ND4L expression is measured. Determine whether MT-ND4L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ACTR3 is perturbed and MT-ND4L expression is measured. Determine whether MT-ND4L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58909
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PIK3R4 is perturbed and the expression of FAM149B1 is measured. Does this perturbation cause a significant change in FAM149B1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PIK3R4 is perturbed and the expression of FAM149B1 is measured. Does this perturbation cause a significant change in FAM149B1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108200
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MBTPS2 is perturbed and PMAIP1 expression is quantified. Does this perturbation result in a significant change in PMAIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MBTPS2 is perturbed and PMAIP1 expression is quantified. Does this perturbation result in a significant change in PMAIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32572
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS10 and examine the expression of RPS15A. Does perturbing MRPS10 lead to a significant change in RPS15A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPS10 and examine the expression of RPS15A. Does perturbing MRPS10 lead to a significant change in RPS15A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65381
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of DCTN6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of DCTN6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109687
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SART1 is perturbed and ITPR1 expression is observed. Does this perturbation lead to a significant difference in ITPR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SART1 is perturbed and ITPR1 expression is observed. Does this perturbation lead to a significant difference in ITPR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6603
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL23 is perturbed and SPAG4 expression is quantified. Does this perturbation result in a significant change in SPAG4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL23 is perturbed and SPAG4 expression is quantified. Does this perturbation result in a significant change in SPAG4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66632
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3H, does the expression profile of SNRPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF3H, does the expression profile of SNRPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91457
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBCA is perturbed and ANKLE2 expression is observed. Does this perturbation lead to a significant difference in ANKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBCA is perturbed and ANKLE2 expression is observed. Does this perturbation lead to a significant difference in ANKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5013
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SUPT6H is perturbed and SLC25A29 expression is observed. Does this perturbation lead to a significant difference in SLC25A29 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SUPT6H is perturbed and SLC25A29 expression is observed. Does this perturbation lead to a significant difference in SLC25A29 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105153
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNOT1 is perturbed and CEP57L1 expression is quantified. Does this perturbation result in a significant change in CEP57L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNOT1 is perturbed and CEP57L1 expression is quantified. Does this perturbation result in a significant change in CEP57L1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50242
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDC42 and monitor ARL6IP5 expression. Decide whether this perturbation leads to a significant alteration in ARL6IP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDC42 and monitor ARL6IP5 expression. Decide whether this perturbation leads to a significant alteration in ARL6IP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86638
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDTC1 is perturbed and the expression of KIF13B is measured. Determine whether KIF13B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, WDTC1 is perturbed and the expression of KIF13B is measured. Determine whether KIF13B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3126
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDC6 is perturbed and UBE2E2 expression is observed. Does this perturbation lead to a significant difference in UBE2E2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDC6 is perturbed and UBE2E2 expression is observed. Does this perturbation lead to a significant difference in UBE2E2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5653
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPD1 is perturbed and the expression of GADD45A is measured. Determine whether GADD45A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPD1 is perturbed and the expression of GADD45A is measured. Determine whether GADD45A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94916
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC1 and examine the expression of SERINC3. Does perturbing THOC1 lead to a significant change in SERINC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb THOC1 and examine the expression of SERINC3. Does perturbing THOC1 lead to a significant change in SERINC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100811
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CENPK and then measure expression of PXDC1. Does this perturbation cause a significant change in PXDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CENPK and then measure expression of PXDC1. Does this perturbation cause a significant change in PXDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26264
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM5 is perturbed and the expression of RND3 is measured. Does this perturbation cause a significant change in RND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LSM5 is perturbed and the expression of RND3 is measured. Does this perturbation cause a significant change in RND3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85630
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NARS is perturbed and DYRK4 expression is observed. Does this perturbation lead to a significant difference in DYRK4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NARS is perturbed and DYRK4 expression is observed. Does this perturbation lead to a significant difference in DYRK4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8883
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NELFA and then measure expression of ITGAV. Does this perturbation cause a significant change in ITGAV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NELFA and then measure expression of ITGAV. Does this perturbation cause a significant change in ITGAV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99074
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL9 and then measure expression of C1orf122. Does this perturbation cause a significant change in C1orf122 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL9 and then measure expression of C1orf122. Does this perturbation cause a significant change in C1orf122 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118144
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LDB1 is associated with a significant change in MYH10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LDB1 is associated with a significant change in MYH10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111085
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which THAP1 is perturbed and SUPT7L expression is observed. Does this perturbation lead to a significant difference in SUPT7L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which THAP1 is perturbed and SUPT7L expression is observed. Does this perturbation lead to a significant difference in SUPT7L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20373
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of SCD is measured. Determine whether SCD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of SCD is measured. Determine whether SCD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50496
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UPF1 is perturbed and DNAJC17 expression is observed. Does this perturbation lead to a significant difference in DNAJC17 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UPF1 is perturbed and DNAJC17 expression is observed. Does this perturbation lead to a significant difference in DNAJC17 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88113
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM48 and examine the expression of NDST2. Does perturbing RBM48 lead to a significant change in NDST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RBM48 and examine the expression of NDST2. Does perturbing RBM48 lead to a significant change in NDST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96361
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARPC2 and then measure expression of PPIB. Does this perturbation cause a significant change in PPIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARPC2 and then measure expression of PPIB. Does this perturbation cause a significant change in PPIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52984
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR1C is perturbed and the expression of PALMD is measured. Determine whether PALMD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR1C is perturbed and the expression of PALMD is measured. Determine whether PALMD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60616
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NFYB and monitor IFI27L2 expression. Decide whether this perturbation leads to a significant alteration in IFI27L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NFYB and monitor IFI27L2 expression. Decide whether this perturbation leads to a significant alteration in IFI27L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78618
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK2 is associated with a significant change in DDX55 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDK2 is associated with a significant change in DDX55 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66685
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in TXN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED27 is associated with a significant change in TXN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122705
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD13 and examine the expression of CEBPZOS. Does perturbing PSMD13 lead to a significant change in CEBPZOS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD13 and examine the expression of CEBPZOS. Does perturbing PSMD13 lead to a significant change in CEBPZOS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79241
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, METTL14 is perturbed and RBMX2 expression is measured. Determine whether RBMX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, METTL14 is perturbed and RBMX2 expression is measured. Determine whether RBMX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85019
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MOK, does the expression profile of HSPB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MOK, does the expression profile of HSPB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32687
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS31 is perturbed and the expression of CYB5R1 is measured. Determine whether CYB5R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPS31 is perturbed and the expression of CYB5R1 is measured. Determine whether CYB5R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRORP and then measure expression of WEE1. Does this perturbation cause a significant change in WEE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRORP and then measure expression of WEE1. Does this perturbation cause a significant change in WEE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9314
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COQ4 is perturbed and PDSS2 expression is measured. Determine whether PDSS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COQ4 is perturbed and PDSS2 expression is measured. Determine whether PDSS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119259
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL38 is perturbed and the expression of YIPF5 is measured. Determine whether YIPF5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL38 is perturbed and the expression of YIPF5 is measured. Determine whether YIPF5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41576
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ACD is perturbed and DENND10 expression is quantified. Does this perturbation result in a significant change in DENND10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ACD is perturbed and DENND10 expression is quantified. Does this perturbation result in a significant change in DENND10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59622
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UCHL5 and monitor RBL2 expression. Decide whether this perturbation leads to a significant alteration in RBL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UCHL5 and monitor RBL2 expression. Decide whether this perturbation leads to a significant alteration in RBL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25548
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GARS is perturbed and the expression of ASMTL is measured. Does this perturbation cause a significant change in ASMTL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GARS is perturbed and the expression of ASMTL is measured. Does this perturbation cause a significant change in ASMTL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30900
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3J and then measure expression of MED4. Does this perturbation cause a significant change in MED4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF3J and then measure expression of MED4. Does this perturbation cause a significant change in MED4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12234
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRPF40A is perturbed and SNHG1 expression is observed. Does this perturbation lead to a significant difference in SNHG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRPF40A is perturbed and SNHG1 expression is observed. Does this perturbation lead to a significant difference in SNHG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113523
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL20 and then measure expression of HERC3. Does this perturbation cause a significant change in HERC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL20 and then measure expression of HERC3. Does this perturbation cause a significant change in HERC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18254
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAD2L2, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAD2L2, does the expression profile of SELENOM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30997
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB4 is perturbed and the expression of NDST1 is measured. Does this perturbation cause a significant change in NDST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB4 is perturbed and the expression of NDST1 is measured. Does this perturbation cause a significant change in NDST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90160
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM4, does the expression profile of AC016831.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM4, does the expression profile of AC016831.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107307
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KPNA6 is perturbed and TP53TG1 expression is observed. Does this perturbation lead to a significant difference in TP53TG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KPNA6 is perturbed and TP53TG1 expression is observed. Does this perturbation lead to a significant difference in TP53TG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12483
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAE1 is perturbed and AC016831.7 expression is quantified. Does this perturbation result in a significant change in AC016831.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAE1 is perturbed and AC016831.7 expression is quantified. Does this perturbation result in a significant change in AC016831.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46962
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPS21 and monitor RALGAPA1 expression. Decide whether this perturbation leads to a significant alteration in RALGAPA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPS21 and monitor RALGAPA1 expression. Decide whether this perturbation leads to a significant alteration in RALGAPA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77678
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX5B and then measure expression of NAV3. Does this perturbation cause a significant change in NAV3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COX5B and then measure expression of NAV3. Does this perturbation cause a significant change in NAV3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82464
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB10 is perturbed and the expression of ITFG1 is measured. Does this perturbation cause a significant change in ITFG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NDUFB10 is perturbed and the expression of ITFG1 is measured. Does this perturbation cause a significant change in ITFG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104770
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and NOSIP expression is observed. Does this perturbation lead to a significant difference in NOSIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and NOSIP expression is observed. Does this perturbation lead to a significant difference in NOSIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45363
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL19 is perturbed and IRF1 expression is measured. Determine whether IRF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL19 is perturbed and IRF1 expression is measured. Determine whether IRF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8579
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LONP1 and monitor LRRC75A expression. Decide whether this perturbation leads to a significant alteration in LRRC75A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LONP1 and monitor LRRC75A expression. Decide whether this perturbation leads to a significant alteration in LRRC75A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77188
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TUBGCP2 is perturbed and MEGF9 expression is measured. Determine whether MEGF9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TUBGCP2 is perturbed and MEGF9 expression is measured. Determine whether MEGF9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46409
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSGEP and examine the expression of PCSK1N. Does perturbing OSGEP lead to a significant change in PCSK1N expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSGEP and examine the expression of PCSK1N. Does perturbing OSGEP lead to a significant change in PCSK1N expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51221
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PMPCA is perturbed and TMEM39A expression is observed. Does this perturbation lead to a significant difference in TMEM39A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PMPCA is perturbed and TMEM39A expression is observed. Does this perturbation lead to a significant difference in TMEM39A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72043
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISY1 is perturbed and the expression of AMZ2 is measured. Determine whether AMZ2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISY1 is perturbed and the expression of AMZ2 is measured. Determine whether AMZ2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104016
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DYNC1H1 is perturbed and WDR11 expression is measured. Determine whether WDR11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DYNC1H1 is perturbed and WDR11 expression is measured. Determine whether WDR11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98479
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DTYMK and monitor CCNDBP1 expression. Decide whether this perturbation leads to a significant alteration in CCNDBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DTYMK and monitor CCNDBP1 expression. Decide whether this perturbation leads to a significant alteration in CCNDBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3688
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RRP15 is perturbed and JPX expression is observed. Does this perturbation lead to a significant difference in JPX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RRP15 is perturbed and JPX expression is observed. Does this perturbation lead to a significant difference in JPX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25213
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPA1 is perturbed and the expression of BBS2 is measured. Determine whether BBS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPA1 is perturbed and the expression of BBS2 is measured. Determine whether BBS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4856
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TCP1 and examine the expression of COPG1. Does perturbing TCP1 lead to a significant change in COPG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TCP1 and examine the expression of COPG1. Does perturbing TCP1 lead to a significant change in COPG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16321
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARPC1B is perturbed and BCL2L13 expression is quantified. Does this perturbation result in a significant change in BCL2L13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARPC1B is perturbed and BCL2L13 expression is quantified. Does this perturbation result in a significant change in BCL2L13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58912
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BOP1 is perturbed and MBNL2 expression is observed. Does this perturbation lead to a significant difference in MBNL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BOP1 is perturbed and MBNL2 expression is observed. Does this perturbation lead to a significant difference in MBNL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12023
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GAPDH and then measure expression of DYRK3. Does this perturbation cause a significant change in DYRK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GAPDH and then measure expression of DYRK3. Does this perturbation cause a significant change in DYRK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54474
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCKAP1, does the expression profile of CCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCKAP1, does the expression profile of CCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32907
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AAAS and then measure expression of PMVK. Does this perturbation cause a significant change in PMVK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AAAS and then measure expression of PMVK. Does this perturbation cause a significant change in PMVK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88174
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, WBP1 is perturbed and the expression of ZBTB24 is measured. Does this perturbation cause a significant change in ZBTB24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, WBP1 is perturbed and the expression of ZBTB24 is measured. Does this perturbation cause a significant change in ZBTB24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":140
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCDC137 is perturbed and SNX1 expression is quantified. Does this perturbation result in a significant change in SNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCDC137 is perturbed and SNX1 expression is quantified. Does this perturbation result in a significant change in SNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41252
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb VPS18 and monitor RNF145 expression. Decide whether this perturbation leads to a significant alteration in RNF145 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb VPS18 and monitor RNF145 expression. Decide whether this perturbation leads to a significant alteration in RNF145 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81588
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and DNAH14 expression is quantified. Does this perturbation result in a significant change in DNAH14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and DNAH14 expression is quantified. Does this perturbation result in a significant change in DNAH14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5562
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GIT2 is perturbed and the expression of SMIM29 is measured. Determine whether SMIM29 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GIT2 is perturbed and the expression of SMIM29 is measured. Determine whether SMIM29 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27126
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GAK and examine the expression of ZDHHC17. Does perturbing GAK lead to a significant change in ZDHHC17 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GAK and examine the expression of ZDHHC17. Does perturbing GAK lead to a significant change in ZDHHC17 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44841
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLE1 is perturbed and DPP7 expression is observed. Does this perturbation lead to a significant difference in DPP7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLE1 is perturbed and DPP7 expression is observed. Does this perturbation lead to a significant difference in DPP7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62403
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TERF1 and monitor CDC42BPA expression. Decide whether this perturbation leads to a significant alteration in CDC42BPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TERF1 and monitor CDC42BPA expression. Decide whether this perturbation leads to a significant alteration in CDC42BPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73858
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHCHD2 is associated with a significant change in RNF216 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHCHD2 is associated with a significant change in RNF216 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77055
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHCY is perturbed and the expression of SMARCD1 is measured. Determine whether SMARCD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHCY is perturbed and the expression of SMARCD1 is measured. Determine whether SMARCD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56496
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C7orf50 is perturbed and the expression of ASAH1 is measured. Determine whether ASAH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C7orf50 is perturbed and the expression of ASAH1 is measured. Determine whether ASAH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112586
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PAF1 is perturbed and the expression of SHOX2 is measured. Determine whether SHOX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PAF1 is perturbed and the expression of SHOX2 is measured. Determine whether SHOX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15546
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FTSJ3 is perturbed and TMCO3 expression is quantified. Does this perturbation result in a significant change in TMCO3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FTSJ3 is perturbed and TMCO3 expression is quantified. Does this perturbation result in a significant change in TMCO3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75192
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC25A26 and then measure expression of MRPS7. Does this perturbation cause a significant change in MRPS7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC25A26 and then measure expression of MRPS7. Does this perturbation cause a significant change in MRPS7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109604
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5PD is perturbed and the expression of STIM1 is measured. Determine whether STIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5PD is perturbed and the expression of STIM1 is measured. Determine whether STIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69646
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRKRA and examine the expression of ENTPD7. Does perturbing PRKRA lead to a significant change in ENTPD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRKRA and examine the expression of ENTPD7. Does perturbing PRKRA lead to a significant change in ENTPD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117301
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBGCP2 is perturbed and the expression of CYFIP2 is measured. Determine whether CYFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TUBGCP2 is perturbed and the expression of CYFIP2 is measured. Determine whether CYFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46366
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MLST8 and monitor WIPI2 expression. Decide whether this perturbation leads to a significant alteration in WIPI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MLST8 and monitor WIPI2 expression. Decide whether this perturbation leads to a significant alteration in WIPI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52638
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN2 is associated with a significant change in PROSER3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN2 is associated with a significant change in PROSER3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15355
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of GAS5 is measured. Determine whether GAS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of GAS5 is measured. Determine whether GAS5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102656
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBM39 is perturbed and CLP1 expression is quantified. Does this perturbation result in a significant change in CLP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBM39 is perturbed and CLP1 expression is quantified. Does this perturbation result in a significant change in CLP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99862
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC7A6OS is perturbed and FBN2 expression is measured. Determine whether FBN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC7A6OS is perturbed and FBN2 expression is measured. Determine whether FBN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31069
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TNPO3 and examine the expression of ZMYM3. Does perturbing TNPO3 lead to a significant change in ZMYM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TNPO3 and examine the expression of ZMYM3. Does perturbing TNPO3 lead to a significant change in ZMYM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14361
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX18 is perturbed and FAM20C expression is measured. Determine whether FAM20C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX18 is perturbed and FAM20C expression is measured. Determine whether FAM20C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80989
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RINT1 is associated with a significant change in YIPF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RINT1 is associated with a significant change in YIPF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76735
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPIA is perturbed and the expression of UNC45A is measured. Determine whether UNC45A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPIA is perturbed and the expression of UNC45A is measured. Determine whether UNC45A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117026
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFAF7 is associated with a significant change in PXDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NDUFAF7 is associated with a significant change in PXDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33855
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC62 is perturbed and TRIT1 expression is observed. Does this perturbation lead to a significant difference in TRIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC62 is perturbed and TRIT1 expression is observed. Does this perturbation lead to a significant difference in TRIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101663
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRRT is perturbed and ZNF23 expression is measured. Determine whether ZNF23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRRT is perturbed and ZNF23 expression is measured. Determine whether ZNF23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57909
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPAP3 is perturbed and KDM5B expression is observed. Does this perturbation lead to a significant difference in KDM5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPAP3 is perturbed and KDM5B expression is observed. Does this perturbation lead to a significant difference in KDM5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87893
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF13 is perturbed and the expression of FANCL is measured. Determine whether FANCL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF13 is perturbed and the expression of FANCL is measured. Determine whether FANCL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23856
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SART1 and monitor ITPR1 expression. Decide whether this perturbation leads to a significant alteration in ITPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SART1 and monitor ITPR1 expression. Decide whether this perturbation leads to a significant alteration in ITPR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6608
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFB3 is perturbed and the expression of MIR222HG is measured. Determine whether MIR222HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NDUFB3 is perturbed and the expression of MIR222HG is measured. Determine whether MIR222HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99546
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF6 is perturbed and the expression of EIF2A is measured. Determine whether EIF2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRPF6 is perturbed and the expression of EIF2A is measured. Determine whether EIF2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30276
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SUDS3 is perturbed and CEBPB expression is quantified. Does this perturbation result in a significant change in CEBPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SUDS3 is perturbed and CEBPB expression is quantified. Does this perturbation result in a significant change in CEBPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57462
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to METTL16 and then measure expression of ITPRID2. Does this perturbation cause a significant change in ITPRID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to METTL16 and then measure expression of ITPRID2. Does this perturbation cause a significant change in ITPRID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53014
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNC1I2 and examine the expression of CREBRF. Does perturbing DYNC1I2 lead to a significant change in CREBRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNC1I2 and examine the expression of CREBRF. Does perturbing DYNC1I2 lead to a significant change in CREBRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116101
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOP14, does the expression profile of ANXA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NOP14, does the expression profile of ANXA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97737
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPAIN is perturbed and PHPT1 expression is measured. Determine whether PHPT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPAIN is perturbed and PHPT1 expression is measured. Determine whether PHPT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107119
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS11 and then measure expression of PLPP4. Does this perturbation cause a significant change in PLPP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to INTS11 and then measure expression of PLPP4. Does this perturbation cause a significant change in PLPP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114894
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PCBP2 is perturbed and LARP4B expression is quantified. Does this perturbation result in a significant change in LARP4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PCBP2 is perturbed and LARP4B expression is quantified. Does this perturbation result in a significant change in LARP4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12782
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C9orf78 is perturbed and the expression of ARL6IP1 is measured. Determine whether ARL6IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C9orf78 is perturbed and the expression of ARL6IP1 is measured. Determine whether ARL6IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29506
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OIP5 is associated with a significant change in PSTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OIP5 is associated with a significant change in PSTK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7695
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TFRC and then measure expression of PLPP3. Does this perturbation cause a significant change in PLPP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TFRC and then measure expression of PLPP3. Does this perturbation cause a significant change in PLPP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23714
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB6A is perturbed and the expression of RBM5 is measured. Determine whether RBM5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RAB6A is perturbed and the expression of RBM5 is measured. Determine whether RBM5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57196
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DCTN5 is perturbed and the expression of CSTF2T is measured. Does this perturbation cause a significant change in CSTF2T expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DCTN5 is perturbed and the expression of CSTF2T is measured. Does this perturbation cause a significant change in CSTF2T expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3730
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PCID2 and then measure expression of DHRS7. Does this perturbation cause a significant change in DHRS7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PCID2 and then measure expression of DHRS7. Does this perturbation cause a significant change in DHRS7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34824
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNRPF and examine the expression of ABHD8. Does perturbing SNRPF lead to a significant change in ABHD8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNRPF and examine the expression of ABHD8. Does perturbing SNRPF lead to a significant change in ABHD8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35801
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SF3B4 is perturbed and SMC5 expression is observed. Does this perturbation lead to a significant difference in SMC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SF3B4 is perturbed and SMC5 expression is observed. Does this perturbation lead to a significant difference in SMC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44943
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDC1 is perturbed and ATF6 expression is observed. Does this perturbation lead to a significant difference in ATF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SDC1 is perturbed and ATF6 expression is observed. Does this perturbation lead to a significant difference in ATF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85733
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCAPD2 is perturbed and ZHX1 expression is observed. Does this perturbation lead to a significant difference in ZHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCAPD2 is perturbed and ZHX1 expression is observed. Does this perturbation lead to a significant difference in ZHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38743
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHORDC1 is perturbed and the expression of SNHG14 is measured. Determine whether SNHG14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHORDC1 is perturbed and the expression of SNHG14 is measured. Determine whether SNHG14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46906
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL37 is perturbed and CD47 expression is observed. Does this perturbation lead to a significant difference in CD47 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL37 is perturbed and CD47 expression is observed. Does this perturbation lead to a significant difference in CD47 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92073
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HLA-C and then measure expression of SNRPC. Does this perturbation cause a significant change in SNRPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HLA-C and then measure expression of SNRPC. Does this perturbation cause a significant change in SNRPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22424
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP4B is perturbed and the expression of HLA-E is measured. Does this perturbation cause a significant change in HLA-E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHMP4B is perturbed and the expression of HLA-E is measured. Does this perturbation cause a significant change in HLA-E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123550
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RRS1 and examine the expression of ATP6AP1. Does perturbing RRS1 lead to a significant change in ATP6AP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RRS1 and examine the expression of ATP6AP1. Does perturbing RRS1 lead to a significant change in ATP6AP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55651
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMB4 is associated with a significant change in SLC38A6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMB4 is associated with a significant change in SLC38A6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102805
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GTF2H2 is perturbed and the expression of TAF10 is measured. Does this perturbation cause a significant change in TAF10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GTF2H2 is perturbed and the expression of TAF10 is measured. Does this perturbation cause a significant change in TAF10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109110
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMA2 and monitor KIAA1217 expression. Decide whether this perturbation leads to a significant alteration in KIAA1217 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMA2 and monitor KIAA1217 expression. Decide whether this perturbation leads to a significant alteration in KIAA1217 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115388
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRSF2, does the expression profile of NORAD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRSF2, does the expression profile of NORAD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98037
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and ICE2 expression is observed. Does this perturbation lead to a significant difference in ICE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and ICE2 expression is observed. Does this perturbation lead to a significant difference in ICE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25013
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CHCHD4 and monitor GOT1 expression. Decide whether this perturbation leads to a significant alteration in GOT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHCHD4 and monitor GOT1 expression. Decide whether this perturbation leads to a significant alteration in GOT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27898
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBBP5, does the expression profile of TRIM24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBBP5, does the expression profile of TRIM24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74087
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF5 is perturbed and ORMDL1 expression is measured. Determine whether ORMDL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TAF5 is perturbed and ORMDL1 expression is measured. Determine whether ORMDL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62689
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and NOL4L expression is quantified. Does this perturbation result in a significant change in NOL4L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and NOL4L expression is quantified. Does this perturbation result in a significant change in NOL4L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11522
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A9 and monitor TCEAL1 expression. Decide whether this perturbation leads to a significant alteration in TCEAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A9 and monitor TCEAL1 expression. Decide whether this perturbation leads to a significant alteration in TCEAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86818
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSEN2, does the expression profile of EIF4A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSEN2, does the expression profile of EIF4A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44517
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R8 is perturbed and the expression of MDK is measured. Does this perturbation cause a significant change in MDK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPP1R8 is perturbed and the expression of MDK is measured. Does this perturbation cause a significant change in MDK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33610
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSA is perturbed and the expression of SCN9A is measured. Determine whether SCN9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSA is perturbed and the expression of SCN9A is measured. Determine whether SCN9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61756
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS14 is perturbed and the expression of ARAF is measured. Determine whether ARAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS14 is perturbed and the expression of ARAF is measured. Determine whether ARAF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34616
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBCB and examine the expression of CPEB4. Does perturbing TBCB lead to a significant change in CPEB4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBCB and examine the expression of CPEB4. Does perturbing TBCB lead to a significant change in CPEB4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105291
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFRC is perturbed and the expression of FST is measured. Determine whether FST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TFRC is perturbed and the expression of FST is measured. Determine whether FST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23726
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4G2 and then measure expression of PLEKHA3. Does this perturbation cause a significant change in PLEKHA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF4G2 and then measure expression of PLEKHA3. Does this perturbation cause a significant change in PLEKHA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53454
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of RPP14 is measured. Does this perturbation cause a significant change in RPP14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of RPP14 is measured. Does this perturbation cause a significant change in RPP14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11160
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFV2 is perturbed and UBXN6 expression is measured. Determine whether UBXN6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NDUFV2 is perturbed and UBXN6 expression is measured. Determine whether UBXN6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28519
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL37 is associated with a significant change in CASP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL37 is associated with a significant change in CASP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7605
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2H4 is perturbed and CAPN7 expression is measured. Determine whether CAPN7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2H4 is perturbed and CAPN7 expression is measured. Determine whether CAPN7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62019
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and PI4K2A expression is quantified. Does this perturbation result in a significant change in PI4K2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and PI4K2A expression is quantified. Does this perturbation result in a significant change in PI4K2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24102
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCS1L and monitor CREBRF expression. Decide whether this perturbation leads to a significant alteration in CREBRF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCS1L and monitor CREBRF expression. Decide whether this perturbation leads to a significant alteration in CREBRF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67538
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GARS is perturbed and CEBPG expression is quantified. Does this perturbation result in a significant change in CEBPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GARS is perturbed and CEBPG expression is quantified. Does this perturbation result in a significant change in CEBPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30872
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZC3H4 and monitor IFFO2 expression. Decide whether this perturbation leads to a significant alteration in IFFO2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZC3H4 and monitor IFFO2 expression. Decide whether this perturbation leads to a significant alteration in IFFO2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22548
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTMA is perturbed and ZNF561 expression is measured. Determine whether ZNF561 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTMA is perturbed and ZNF561 expression is measured. Determine whether ZNF561 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4549
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and GSDME expression is quantified. Does this perturbation result in a significant change in GSDME expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and GSDME expression is quantified. Does this perturbation result in a significant change in GSDME expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72252
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCF11 is perturbed and the expression of AK1 is measured. Determine whether AK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PCF11 is perturbed and the expression of AK1 is measured. Determine whether AK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86266
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SDR39U1 and examine the expression of TBC1D2B. Does perturbing SDR39U1 lead to a significant change in TBC1D2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SDR39U1 and examine the expression of TBC1D2B. Does perturbing SDR39U1 lead to a significant change in TBC1D2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70921
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOSC4 is associated with a significant change in CKAP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EXOSC4 is associated with a significant change in CKAP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59905
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPP38 is perturbed and CREB3L2 expression is observed. Does this perturbation lead to a significant difference in CREB3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPP38 is perturbed and CREB3L2 expression is observed. Does this perturbation lead to a significant difference in CREB3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118993
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED8 is associated with a significant change in TPRG1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MED8 is associated with a significant change in TPRG1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79325
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DYNLL1 is perturbed and the expression of DOK1 is measured. Does this perturbation cause a significant change in DOK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DYNLL1 is perturbed and the expression of DOK1 is measured. Does this perturbation cause a significant change in DOK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94260
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR75 and then measure expression of MDM2. Does this perturbation cause a significant change in MDM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR75 and then measure expression of MDM2. Does this perturbation cause a significant change in MDM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121634
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TNRC6A is perturbed and SART1 expression is observed. Does this perturbation lead to a significant difference in SART1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TNRC6A is perturbed and SART1 expression is observed. Does this perturbation lead to a significant difference in SART1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43923
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LIN54 and monitor UBE2D1 expression. Decide whether this perturbation leads to a significant alteration in UBE2D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LIN54 and monitor UBE2D1 expression. Decide whether this perturbation leads to a significant alteration in UBE2D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56888
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MPHOSPH6 is associated with a significant change in PCMTD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MPHOSPH6 is associated with a significant change in PCMTD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45635
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GFER is associated with a significant change in CHPF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GFER is associated with a significant change in CHPF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100445
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NSMCE2 and examine the expression of TIGAR. Does perturbing NSMCE2 lead to a significant change in TIGAR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NSMCE2 and examine the expression of TIGAR. Does perturbing NSMCE2 lead to a significant change in TIGAR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45951
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CTU2 is perturbed and FNDC3A expression is observed. Does this perturbation lead to a significant difference in FNDC3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CTU2 is perturbed and FNDC3A expression is observed. Does this perturbation lead to a significant difference in FNDC3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93823
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS33A is perturbed and the expression of CIC is measured. Determine whether CIC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, VPS33A is perturbed and the expression of CIC is measured. Determine whether CIC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21166
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRRAP is perturbed and WDR83 expression is quantified. Does this perturbation result in a significant change in WDR83 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRRAP is perturbed and WDR83 expression is quantified. Does this perturbation result in a significant change in WDR83 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109942
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMG1 is perturbed and the expression of RPAIN is measured. Does this perturbation cause a significant change in RPAIN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMG1 is perturbed and the expression of RPAIN is measured. Does this perturbation cause a significant change in RPAIN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111480
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOP16 is associated with a significant change in PTS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NOP16 is associated with a significant change in PTS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108665
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRMT112 is perturbed and ATP6V1H expression is quantified. Does this perturbation result in a significant change in ATP6V1H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRMT112 is perturbed and ATP6V1H expression is quantified. Does this perturbation result in a significant change in ATP6V1H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2072
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TRMT112 is perturbed and AMFR expression is observed. Does this perturbation lead to a significant difference in AMFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TRMT112 is perturbed and AMFR expression is observed. Does this perturbation lead to a significant difference in AMFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2093
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX18, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX18, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80957
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EEF1A1 is perturbed and MPC2 expression is observed. Does this perturbation lead to a significant difference in MPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EEF1A1 is perturbed and MPC2 expression is observed. Does this perturbation lead to a significant difference in MPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69143
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NDUFA6 and examine the expression of RBBP8. Does perturbing NDUFA6 lead to a significant change in RBBP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NDUFA6 and examine the expression of RBBP8. Does perturbing NDUFA6 lead to a significant change in RBBP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38811
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GTF2A1 and monitor HSDL2 expression. Decide whether this perturbation leads to a significant alteration in HSDL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GTF2A1 and monitor HSDL2 expression. Decide whether this perturbation leads to a significant alteration in HSDL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27558
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCAF1 is associated with a significant change in FIP1L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCAF1 is associated with a significant change in FIP1L1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91235
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIP7 is perturbed and the expression of TMED10 is measured. Determine whether TMED10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIP7 is perturbed and the expression of TMED10 is measured. Determine whether TMED10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93166
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HUWE1 is perturbed and NFASC expression is observed. Does this perturbation lead to a significant difference in NFASC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HUWE1 is perturbed and NFASC expression is observed. Does this perturbation lead to a significant difference in NFASC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50263
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf25, does the expression profile of CERS5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf25, does the expression profile of CERS5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112427
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1B is perturbed and DUSP22 expression is measured. Determine whether DUSP22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHAF1B is perturbed and DUSP22 expression is measured. Determine whether DUSP22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90749
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL14 is associated with a significant change in IL4R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPL14 is associated with a significant change in IL4R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74185
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRBD1 is perturbed and ADAM12 expression is quantified. Does this perturbation result in a significant change in ADAM12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRBD1 is perturbed and ADAM12 expression is quantified. Does this perturbation result in a significant change in ADAM12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92022
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTEN and then measure expression of PPP3CC. Does this perturbation cause a significant change in PPP3CC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTEN and then measure expression of PPP3CC. Does this perturbation cause a significant change in PPP3CC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4404
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC25A10 is perturbed and ETHE1 expression is measured. Determine whether ETHE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC25A10 is perturbed and ETHE1 expression is measured. Determine whether ETHE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41909
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMB7 is perturbed and the expression of NEK1 is measured. Determine whether NEK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMB7 is perturbed and the expression of NEK1 is measured. Determine whether NEK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119756
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPT16H and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUPT16H and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114554
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLNS1A is perturbed and the expression of SLFN12 is measured. Determine whether SLFN12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLNS1A is perturbed and the expression of SLFN12 is measured. Determine whether SLFN12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65816
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LETM1 is perturbed and the expression of EGR1 is measured. Determine whether EGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LETM1 is perturbed and the expression of EGR1 is measured. Determine whether EGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59806
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RCC1 is associated with a significant change in ING4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RCC1 is associated with a significant change in ING4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77415
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS2 is perturbed and PGM2 expression is measured. Determine whether PGM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS2 is perturbed and PGM2 expression is measured. Determine whether PGM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80189
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MED10 is perturbed and LATS1 expression is observed. Does this perturbation lead to a significant difference in LATS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MED10 is perturbed and LATS1 expression is observed. Does this perturbation lead to a significant difference in LATS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121123
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MCM3 is perturbed and the expression of HEG1 is measured. Does this perturbation cause a significant change in HEG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MCM3 is perturbed and the expression of HEG1 is measured. Does this perturbation cause a significant change in HEG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5790
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NELFB is perturbed and EDRF1 expression is quantified. Does this perturbation result in a significant change in EDRF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NELFB is perturbed and EDRF1 expression is quantified. Does this perturbation result in a significant change in EDRF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30002
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPDL is perturbed and ZCCHC7 expression is measured. Determine whether ZCCHC7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPDL is perturbed and ZCCHC7 expression is measured. Determine whether ZCCHC7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117989
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAP18 is perturbed and the expression of TAF12 is measured. Does this perturbation cause a significant change in TAF12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAP18 is perturbed and the expression of TAF12 is measured. Does this perturbation cause a significant change in TAF12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121430
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and DNAJC3 expression is measured. Determine whether DNAJC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and DNAJC3 expression is measured. Determine whether DNAJC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6159
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TWISTNB is perturbed and NMNAT2 expression is measured. Determine whether NMNAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TWISTNB is perturbed and NMNAT2 expression is measured. Determine whether NMNAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116789
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX37 is associated with a significant change in COMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHX37 is associated with a significant change in COMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91855
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL43 and then measure expression of KCMF1. Does this perturbation cause a significant change in KCMF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL43 and then measure expression of KCMF1. Does this perturbation cause a significant change in KCMF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39164
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX33 and then measure expression of GOLGA4. Does this perturbation cause a significant change in GOLGA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHX33 and then measure expression of GOLGA4. Does this perturbation cause a significant change in GOLGA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100164
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2H, does the expression profile of PNPLA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POLR2H, does the expression profile of PNPLA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111777
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TPRKB, does the expression profile of OARD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TPRKB, does the expression profile of OARD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89937
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of STX8. Does perturbing QARS lead to a significant change in STX8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of STX8. Does perturbing QARS lead to a significant change in STX8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18681
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL15 and then measure expression of PAM. Does this perturbation cause a significant change in PAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL15 and then measure expression of PAM. Does this perturbation cause a significant change in PAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53394
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NRDE2 is perturbed and TRDMT1 expression is quantified. Does this perturbation result in a significant change in TRDMT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NRDE2 is perturbed and TRDMT1 expression is quantified. Does this perturbation result in a significant change in TRDMT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77222
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM242 and then measure expression of KLHL7. Does this perturbation cause a significant change in KLHL7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM242 and then measure expression of KLHL7. Does this perturbation cause a significant change in KLHL7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5514
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPOX is perturbed and the expression of GNL1 is measured. Determine whether GNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPOX is perturbed and the expression of GNL1 is measured. Determine whether GNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13796
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YEATS2 and then measure expression of TAX1BP3. Does this perturbation cause a significant change in TAX1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YEATS2 and then measure expression of TAX1BP3. Does this perturbation cause a significant change in TAX1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26654
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTCD3 and monitor EXOC6B expression. Decide whether this perturbation leads to a significant alteration in EXOC6B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTCD3 and monitor EXOC6B expression. Decide whether this perturbation leads to a significant alteration in EXOC6B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118848
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHD4 and examine the expression of DYSF. Does perturbing CHD4 lead to a significant change in DYSF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHD4 and examine the expression of DYSF. Does perturbing CHD4 lead to a significant change in DYSF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14321
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of TRIM8 is measured. Determine whether TRIM8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of TRIM8 is measured. Determine whether TRIM8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103086
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRSF10, does the expression profile of KLF16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRSF10, does the expression profile of KLF16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85437
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KDM2A is perturbed and MTHFD2L expression is measured. Determine whether MTHFD2L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KDM2A is perturbed and MTHFD2L expression is measured. Determine whether MTHFD2L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3539
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP214 is perturbed and LMO4 expression is observed. Does this perturbation lead to a significant difference in LMO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP214 is perturbed and LMO4 expression is observed. Does this perturbation lead to a significant difference in LMO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103733
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLC2 is perturbed and SMG6 expression is measured. Determine whether SMG6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLC2 is perturbed and SMG6 expression is measured. Determine whether SMG6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20669
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of NFIA is measured. Does this perturbation cause a significant change in NFIA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of NFIA is measured. Does this perturbation cause a significant change in NFIA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50950
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FBXO5 and monitor FAM210B expression. Decide whether this perturbation leads to a significant alteration in FAM210B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FBXO5 and monitor FAM210B expression. Decide whether this perturbation leads to a significant alteration in FAM210B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123008
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2A is perturbed and USP25 expression is quantified. Does this perturbation result in a significant change in USP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POLR2A is perturbed and USP25 expression is quantified. Does this perturbation result in a significant change in USP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106482
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUBP2 is associated with a significant change in TMEM115 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NUBP2 is associated with a significant change in TMEM115 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59025
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FAM50A and monitor C8orf33 expression. Decide whether this perturbation leads to a significant alteration in C8orf33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FAM50A and monitor C8orf33 expression. Decide whether this perturbation leads to a significant alteration in C8orf33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19708
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UPF2, does the expression profile of FAM214B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UPF2, does the expression profile of FAM214B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19167
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB4 is perturbed and the expression of DMWD is measured. Does this perturbation cause a significant change in DMWD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB4 is perturbed and the expression of DMWD is measured. Does this perturbation cause a significant change in DMWD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37190
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAF11 is perturbed and NBPF14 expression is quantified. Does this perturbation result in a significant change in NBPF14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TAF11 is perturbed and NBPF14 expression is quantified. Does this perturbation result in a significant change in NBPF14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15042
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LAS1L is perturbed and the expression of MAPK6 is measured. Does this perturbation cause a significant change in MAPK6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LAS1L is perturbed and the expression of MAPK6 is measured. Does this perturbation cause a significant change in MAPK6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39090
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL21 is perturbed and PVT1 expression is observed. Does this perturbation lead to a significant difference in PVT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL21 is perturbed and PVT1 expression is observed. Does this perturbation lead to a significant difference in PVT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37763
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF2F2 is perturbed and the expression of ZNF451 is measured. Determine whether ZNF451 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GTF2F2 is perturbed and the expression of ZNF451 is measured. Determine whether ZNF451 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58826
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPZ, does the expression profile of LRIG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPZ, does the expression profile of LRIG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91067
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHORDC1 is associated with a significant change in SNHG14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHORDC1 is associated with a significant change in SNHG14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46905
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS4 is perturbed and the expression of LTA4H is measured. Determine whether LTA4H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, INTS4 is perturbed and the expression of LTA4H is measured. Determine whether LTA4H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108816
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KANSL2 and monitor MXD4 expression. Decide whether this perturbation leads to a significant alteration in MXD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KANSL2 and monitor MXD4 expression. Decide whether this perturbation leads to a significant alteration in MXD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82378
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in LINC00662 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in LINC00662 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58675
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NISCH is perturbed and the expression of NMRAL1 is measured. Does this perturbation cause a significant change in NMRAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NISCH is perturbed and the expression of NMRAL1 is measured. Does this perturbation cause a significant change in NMRAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21870
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR3D is perturbed and the expression of TIMM50 is measured. Determine whether TIMM50 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POLR3D is perturbed and the expression of TIMM50 is measured. Determine whether TIMM50 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104986
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ANAPC10 is perturbed and the expression of TIMM8B is measured. Does this perturbation cause a significant change in TIMM8B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ANAPC10 is perturbed and the expression of TIMM8B is measured. Does this perturbation cause a significant change in TIMM8B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57280
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BRCA1 and then measure expression of YME1L1. Does this perturbation cause a significant change in YME1L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BRCA1 and then measure expression of YME1L1. Does this perturbation cause a significant change in YME1L1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121674
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP2R3C and examine the expression of KDELR3. Does perturbing PPP2R3C lead to a significant change in KDELR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP2R3C and examine the expression of KDELR3. Does perturbing PPP2R3C lead to a significant change in KDELR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43611
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HDAC7 is perturbed and TUSC2 expression is observed. Does this perturbation lead to a significant difference in TUSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HDAC7 is perturbed and TUSC2 expression is observed. Does this perturbation lead to a significant difference in TUSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110393
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PAK1IP1 and examine the expression of SMG9. Does perturbing PAK1IP1 lead to a significant change in SMG9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PAK1IP1 and examine the expression of SMG9. Does perturbing PAK1IP1 lead to a significant change in SMG9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71361
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RTCB is perturbed and ZNF618 expression is quantified. Does this perturbation result in a significant change in ZNF618 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RTCB is perturbed and ZNF618 expression is quantified. Does this perturbation result in a significant change in ZNF618 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18472
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZMAT2 is perturbed and YPEL5 expression is quantified. Does this perturbation result in a significant change in YPEL5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZMAT2 is perturbed and YPEL5 expression is quantified. Does this perturbation result in a significant change in YPEL5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5112
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STX18 and monitor TTC17 expression. Decide whether this perturbation leads to a significant alteration in TTC17 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STX18 and monitor TTC17 expression. Decide whether this perturbation leads to a significant alteration in TTC17 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30728
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FNBP4 is perturbed and ZNF395 expression is quantified. Does this perturbation result in a significant change in ZNF395 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FNBP4 is perturbed and ZNF395 expression is quantified. Does this perturbation result in a significant change in ZNF395 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41822
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SKA1 and examine the expression of TRIAP1. Does perturbing SKA1 lead to a significant change in TRIAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SKA1 and examine the expression of TRIAP1. Does perturbing SKA1 lead to a significant change in TRIAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66251
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TADA2B is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TADA2B is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33519
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and TESK1 expression is observed. Does this perturbation lead to a significant difference in TESK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and TESK1 expression is observed. Does this perturbation lead to a significant difference in TESK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101923
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FAU is perturbed and IGFBP3 expression is quantified. Does this perturbation result in a significant change in IGFBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FAU is perturbed and IGFBP3 expression is quantified. Does this perturbation result in a significant change in IGFBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34112
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBE2M and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBE2M and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7754
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YEATS4, does the expression profile of PLCB4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YEATS4, does the expression profile of PLCB4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34457
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WBP1L is perturbed and ARFRP1 expression is quantified. Does this perturbation result in a significant change in ARFRP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, WBP1L is perturbed and ARFRP1 expression is quantified. Does this perturbation result in a significant change in ARFRP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60062
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USP5, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of USP5, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67317
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AP2M1 is associated with a significant change in PPARD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AP2M1 is associated with a significant change in PPARD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18315
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INO80, does the expression profile of ACAA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of INO80, does the expression profile of ACAA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108087
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SKP1 is perturbed and TLE4 expression is observed. Does this perturbation lead to a significant difference in TLE4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SKP1 is perturbed and TLE4 expression is observed. Does this perturbation lead to a significant difference in TLE4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107753
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM199, does the expression profile of PMM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM199, does the expression profile of PMM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9877
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RIOK1 is perturbed and the expression of ELP1 is measured. Does this perturbation cause a significant change in ELP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RIOK1 is perturbed and the expression of ELP1 is measured. Does this perturbation cause a significant change in ELP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15860
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR74 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, WDR74 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55880
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and DENND5A expression is observed. Does this perturbation lead to a significant difference in DENND5A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and DENND5A expression is observed. Does this perturbation lead to a significant difference in DENND5A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25483
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL41 is perturbed and PIGG expression is measured. Determine whether PIGG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPL41 is perturbed and PIGG expression is measured. Determine whether PIGG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22599
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TPX2 is perturbed and TTC17 expression is measured. Determine whether TTC17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TPX2 is perturbed and TTC17 expression is measured. Determine whether TTC17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115799
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UTP3 and then measure expression of ITCH. Does this perturbation cause a significant change in ITCH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UTP3 and then measure expression of ITCH. Does this perturbation cause a significant change in ITCH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108974
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DYNLRB1 is associated with a significant change in CBL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DYNLRB1 is associated with a significant change in CBL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67045
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRKCA is perturbed and REV1 expression is measured. Determine whether REV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRKCA is perturbed and REV1 expression is measured. Determine whether REV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54099
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UPF1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UPF1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88070
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HUWE1 and monitor OPTN expression. Decide whether this perturbation leads to a significant alteration in OPTN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HUWE1 and monitor OPTN expression. Decide whether this perturbation leads to a significant alteration in OPTN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50278
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CWC22 is perturbed and the expression of RBM22 is measured. Determine whether RBM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CWC22 is perturbed and the expression of RBM22 is measured. Determine whether RBM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74336
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS10 is perturbed and PLEKHB2 expression is quantified. Does this perturbation result in a significant change in PLEKHB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS10 is perturbed and PLEKHB2 expression is quantified. Does this perturbation result in a significant change in PLEKHB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117252
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABT1 and examine the expression of NPHP3. Does perturbing ABT1 lead to a significant change in NPHP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ABT1 and examine the expression of NPHP3. Does perturbing ABT1 lead to a significant change in NPHP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120891
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDX41 is perturbed and ARL8A expression is observed. Does this perturbation lead to a significant difference in ARL8A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDX41 is perturbed and ARL8A expression is observed. Does this perturbation lead to a significant difference in ARL8A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104453
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CXXC1 is perturbed and AP4E1 expression is observed. Does this perturbation lead to a significant difference in AP4E1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CXXC1 is perturbed and AP4E1 expression is observed. Does this perturbation lead to a significant difference in AP4E1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67643
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP6V1H is perturbed and BRMS1 expression is quantified. Does this perturbation result in a significant change in BRMS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP6V1H is perturbed and BRMS1 expression is quantified. Does this perturbation result in a significant change in BRMS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53292
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AP2A1 and monitor CHD2 expression. Decide whether this perturbation leads to a significant alteration in CHD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AP2A1 and monitor CHD2 expression. Decide whether this perturbation leads to a significant alteration in CHD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96048
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GET3 and then measure expression of SEC24D. Does this perturbation cause a significant change in SEC24D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GET3 and then measure expression of SEC24D. Does this perturbation cause a significant change in SEC24D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61394
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2H3 is perturbed and MPV17 expression is measured. Determine whether MPV17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GTF2H3 is perturbed and MPV17 expression is measured. Determine whether MPV17 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58289
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAA20 and examine the expression of CDK6. Does perturbing NAA20 lead to a significant change in CDK6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAA20 and examine the expression of CDK6. Does perturbing NAA20 lead to a significant change in CDK6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":651
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SUPV3L1 is perturbed and PDPR expression is measured. Determine whether PDPR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SUPV3L1 is perturbed and PDPR expression is measured. Determine whether PDPR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60139
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PEF1 is perturbed and the expression of PSMD8 is measured. Does this perturbation cause a significant change in PSMD8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PEF1 is perturbed and the expression of PSMD8 is measured. Does this perturbation cause a significant change in PSMD8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94420
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ANKRD11 is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ANKRD11 is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65949
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IMPDH2, does the expression profile of GJC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IMPDH2, does the expression profile of GJC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10177
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KPNB1 is associated with a significant change in BLOC1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KPNB1 is associated with a significant change in BLOC1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20495
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRD8 is associated with a significant change in GYS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRD8 is associated with a significant change in GYS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93895
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb URI1 and examine the expression of CCDC127. Does perturbing URI1 lead to a significant change in CCDC127 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb URI1 and examine the expression of CCDC127. Does perturbing URI1 lead to a significant change in CCDC127 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84721
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP85 is perturbed and XPC expression is observed. Does this perturbation lead to a significant difference in XPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUP85 is perturbed and XPC expression is observed. Does this perturbation lead to a significant difference in XPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18813
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TNRC6A is perturbed and the expression of ZMAT5 is measured. Determine whether ZMAT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TNRC6A is perturbed and the expression of ZMAT5 is measured. Determine whether ZMAT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43916
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPH1 is perturbed and BPTF expression is measured. Determine whether BPTF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNRNPH1 is perturbed and BPTF expression is measured. Determine whether BPTF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22019
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAK16 is perturbed and the expression of ATG101 is measured. Determine whether ATG101 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAK16 is perturbed and the expression of ATG101 is measured. Determine whether ATG101 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89576
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAF6 is associated with a significant change in SPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TAF6 is associated with a significant change in SPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69845
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2F is associated with a significant change in KDELR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POLR2F is associated with a significant change in KDELR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27505
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL49, does the expression profile of ITPRIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL49, does the expression profile of ITPRIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33767
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1F is perturbed and MID1 expression is measured. Determine whether MID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1F is perturbed and MID1 expression is measured. Determine whether MID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105219
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BRIX1 is perturbed and GPT2 expression is quantified. Does this perturbation result in a significant change in GPT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BRIX1 is perturbed and GPT2 expression is quantified. Does this perturbation result in a significant change in GPT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86622
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MBD3 is associated with a significant change in NEIL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MBD3 is associated with a significant change in NEIL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76545
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPAIN and then measure expression of KLF7. Does this perturbation cause a significant change in KLF7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPAIN and then measure expression of KLF7. Does this perturbation cause a significant change in KLF7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107134
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP14, does the expression profile of ATXN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP14, does the expression profile of ATXN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65027
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RSL24D1 is perturbed and the expression of PSMB1 is measured. Determine whether PSMB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RSL24D1 is perturbed and the expression of PSMB1 is measured. Determine whether PSMB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53726
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR33 is associated with a significant change in HRAS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of WDR33 is associated with a significant change in HRAS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31745
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor SLC36A4 expression. Decide whether this perturbation leads to a significant alteration in SLC36A4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor SLC36A4 expression. Decide whether this perturbation leads to a significant alteration in SLC36A4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92518
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TERF1 is perturbed and the expression of CHST14 is measured. Does this perturbation cause a significant change in CHST14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TERF1 is perturbed and the expression of CHST14 is measured. Does this perturbation cause a significant change in CHST14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73900
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RFT1 is perturbed and DBNDD2 expression is measured. Determine whether DBNDD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RFT1 is perturbed and DBNDD2 expression is measured. Determine whether DBNDD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31319
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of C7orf26. Does this perturbation cause a significant change in C7orf26 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of C7orf26. Does this perturbation cause a significant change in C7orf26 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45254
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCAPG2, does the expression profile of RNF139 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCAPG2, does the expression profile of RNF139 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96937
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BUB1B and monitor PKM expression. Decide whether this perturbation leads to a significant alteration in PKM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BUB1B and monitor PKM expression. Decide whether this perturbation leads to a significant alteration in PKM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77858
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHTOP is perturbed and MIR4458HG expression is measured. Determine whether MIR4458HG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHTOP is perturbed and MIR4458HG expression is measured. Determine whether MIR4458HG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23069
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAF2, does the expression profile of PRIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FAF2, does the expression profile of PRIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42997
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TEFM and then measure expression of MDK. Does this perturbation cause a significant change in MDK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TEFM and then measure expression of MDK. Does this perturbation cause a significant change in MDK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33984
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF787 is associated with a significant change in PLAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF787 is associated with a significant change in PLAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102335
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RSL24D1, does the expression profile of PAPPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RSL24D1, does the expression profile of PAPPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53697
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COA5 is perturbed and BLOC1S5 expression is observed. Does this perturbation lead to a significant difference in BLOC1S5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COA5 is perturbed and BLOC1S5 expression is observed. Does this perturbation lead to a significant difference in BLOC1S5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84523
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL22 and monitor C7orf26 expression. Decide whether this perturbation leads to a significant alteration in C7orf26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL22 and monitor C7orf26 expression. Decide whether this perturbation leads to a significant alteration in C7orf26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84168
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC10 is perturbed and IFI27L2 expression is measured. Determine whether IFI27L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EXOSC10 is perturbed and IFI27L2 expression is measured. Determine whether IFI27L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56539
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RGP1 is perturbed and MPC1 expression is quantified. Does this perturbation result in a significant change in MPC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RGP1 is perturbed and MPC1 expression is quantified. Does this perturbation result in a significant change in MPC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80642
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMNDC1 is perturbed and PLEKHG3 expression is quantified. Does this perturbation result in a significant change in PLEKHG3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SMNDC1 is perturbed and PLEKHG3 expression is quantified. Does this perturbation result in a significant change in PLEKHG3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63222
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP6V0C is perturbed and the expression of RNF139 is measured. Determine whether RNF139 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP6V0C is perturbed and the expression of RNF139 is measured. Determine whether RNF139 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42616
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBM19 is perturbed and RTCA expression is observed. Does this perturbation lead to a significant difference in RTCA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RBM19 is perturbed and RTCA expression is observed. Does this perturbation lead to a significant difference in RTCA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106813
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX46 is perturbed and PNRC1 expression is measured. Determine whether PNRC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX46 is perturbed and PNRC1 expression is measured. Determine whether PNRC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1089
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF10 is perturbed and the expression of SPTLC1 is measured. Determine whether SPTLC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TAF10 is perturbed and the expression of SPTLC1 is measured. Determine whether SPTLC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122066
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPB is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNRPB is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105650
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUTF2 is perturbed and MARCH3 expression is observed. Does this perturbation lead to a significant difference in MARCH3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NUTF2 is perturbed and MARCH3 expression is observed. Does this perturbation lead to a significant difference in MARCH3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42553
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPIH is perturbed and the expression of DNAJB4 is measured. Does this perturbation cause a significant change in DNAJB4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPIH is perturbed and the expression of DNAJB4 is measured. Does this perturbation cause a significant change in DNAJB4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104040
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HMGCR is perturbed and the expression of NKX2-5 is measured. Does this perturbation cause a significant change in NKX2-5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HMGCR is perturbed and the expression of NKX2-5 is measured. Does this perturbation cause a significant change in NKX2-5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91000
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RSL1D1 and monitor TMEM41A expression. Decide whether this perturbation leads to a significant alteration in TMEM41A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RSL1D1 and monitor TMEM41A expression. Decide whether this perturbation leads to a significant alteration in TMEM41A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46468
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TUBA1C is associated with a significant change in OTUD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TUBA1C is associated with a significant change in OTUD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85885
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LRR1 is perturbed and the expression of MFHAS1 is measured. Does this perturbation cause a significant change in MFHAS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LRR1 is perturbed and the expression of MFHAS1 is measured. Does this perturbation cause a significant change in MFHAS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102210
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBE2I is perturbed and the expression of NIPSNAP1 is measured. Determine whether NIPSNAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBE2I is perturbed and the expression of NIPSNAP1 is measured. Determine whether NIPSNAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77706
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRKRA is perturbed and ENTPD7 expression is measured. Determine whether ENTPD7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRKRA is perturbed and ENTPD7 expression is measured. Determine whether ENTPD7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117309
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NDUFB4 and monitor CA9 expression. Decide whether this perturbation leads to a significant alteration in CA9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NDUFB4 and monitor CA9 expression. Decide whether this perturbation leads to a significant alteration in CA9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90128
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AFG3L2 and monitor ZYX expression. Decide whether this perturbation leads to a significant alteration in ZYX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AFG3L2 and monitor ZYX expression. Decide whether this perturbation leads to a significant alteration in ZYX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88008
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNC1I2 and examine the expression of DDX60L. Does perturbing DYNC1I2 lead to a significant change in DDX60L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DYNC1I2 and examine the expression of DDX60L. Does perturbing DYNC1I2 lead to a significant change in DDX60L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116141
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCTN5 is perturbed and the expression of BIRC6 is measured. Determine whether BIRC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DCTN5 is perturbed and the expression of BIRC6 is measured. Determine whether BIRC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3746
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BRK1 is perturbed and the expression of ZNF280D is measured. Does this perturbation cause a significant change in ZNF280D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BRK1 is perturbed and the expression of ZNF280D is measured. Does this perturbation cause a significant change in ZNF280D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71860
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPS20 and monitor ATP6V1G1 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1G1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPS20 and monitor ATP6V1G1 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1G1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84968
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb QRSL1 and monitor AGO3 expression. Decide whether this perturbation leads to a significant alteration in AGO3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb QRSL1 and monitor AGO3 expression. Decide whether this perturbation leads to a significant alteration in AGO3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27768
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUD31 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BUD31 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36572
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PFDN2 and then measure expression of UQCC1. Does this perturbation cause a significant change in UQCC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PFDN2 and then measure expression of UQCC1. Does this perturbation cause a significant change in UQCC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91184
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPA is associated with a significant change in SETD7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNRPA is associated with a significant change in SETD7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58545
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1H, does the expression profile of GBA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP6V1H, does the expression profile of GBA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53287
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YPEL5 is associated with a significant change in SIRPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YPEL5 is associated with a significant change in SIRPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44325
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR1D and examine the expression of SPOCK1. Does perturbing POLR1D lead to a significant change in SPOCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POLR1D and examine the expression of SPOCK1. Does perturbing POLR1D lead to a significant change in SPOCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121251
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RNF168 and monitor NOVA1 expression. Decide whether this perturbation leads to a significant alteration in NOVA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RNF168 and monitor NOVA1 expression. Decide whether this perturbation leads to a significant alteration in NOVA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100928
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED8 is perturbed and the expression of TPRG1L is measured. Determine whether TPRG1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MED8 is perturbed and the expression of TPRG1L is measured. Determine whether TPRG1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79326
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GPN2 and examine the expression of TNS1. Does perturbing GPN2 lead to a significant change in TNS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GPN2 and examine the expression of TNS1. Does perturbing GPN2 lead to a significant change in TNS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98651
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ORC1 and examine the expression of LRP10. Does perturbing ORC1 lead to a significant change in LRP10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ORC1 and examine the expression of LRP10. Does perturbing ORC1 lead to a significant change in LRP10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50091
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IK is associated with a significant change in PLK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IK is associated with a significant change in PLK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5165
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAX and examine the expression of PTPRF. Does perturbing MAX lead to a significant change in PTPRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAX and examine the expression of PTPRF. Does perturbing MAX lead to a significant change in PTPRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95891
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUFIP1 and examine the expression of ADD1. Does perturbing NUFIP1 lead to a significant change in ADD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NUFIP1 and examine the expression of ADD1. Does perturbing NUFIP1 lead to a significant change in ADD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9111
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL3 and then measure expression of STRN4. Does this perturbation cause a significant change in STRN4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL3 and then measure expression of STRN4. Does this perturbation cause a significant change in STRN4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80784
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPZ is perturbed and the expression of PCDH10 is measured. Does this perturbation cause a significant change in PCDH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPZ is perturbed and the expression of PCDH10 is measured. Does this perturbation cause a significant change in PCDH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91030
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNRNPR and examine the expression of CIR1. Does perturbing HNRNPR lead to a significant change in CIR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNRNPR and examine the expression of CIR1. Does perturbing HNRNPR lead to a significant change in CIR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45751
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PHB is perturbed and the expression of PCSK1N is measured. Does this perturbation cause a significant change in PCSK1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PHB is perturbed and the expression of PCSK1N is measured. Does this perturbation cause a significant change in PCSK1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26750
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF1 and then measure expression of NDUFB4. Does this perturbation cause a significant change in NDUFB4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF1 and then measure expression of NDUFB4. Does this perturbation cause a significant change in NDUFB4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38694
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS16 is perturbed and GCFC2 expression is quantified. Does this perturbation result in a significant change in GCFC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPS16 is perturbed and GCFC2 expression is quantified. Does this perturbation result in a significant change in GCFC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16652
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRNT1 is perturbed and FBN2 expression is measured. Determine whether FBN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TRNT1 is perturbed and FBN2 expression is measured. Determine whether FBN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2029
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LEO1 is perturbed and FBXO32 expression is observed. Does this perturbation lead to a significant difference in FBXO32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LEO1 is perturbed and FBXO32 expression is observed. Does this perturbation lead to a significant difference in FBXO32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34353
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RTRAF is perturbed and FAM210B expression is measured. Determine whether FAM210B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RTRAF is perturbed and FAM210B expression is measured. Determine whether FAM210B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57379
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NUMA1 and monitor DTWD1 expression. Decide whether this perturbation leads to a significant alteration in DTWD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NUMA1 and monitor DTWD1 expression. Decide whether this perturbation leads to a significant alteration in DTWD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110338
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM6, does the expression profile of ERGIC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MCM6, does the expression profile of ERGIC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24157
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBX1, does the expression profile of SRD5A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RBX1, does the expression profile of SRD5A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57097
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TUBGCP3 is perturbed and the expression of SETDB1 is measured. Does this perturbation cause a significant change in SETDB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TUBGCP3 is perturbed and the expression of SETDB1 is measured. Does this perturbation cause a significant change in SETDB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89840
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPD1 is perturbed and MIRLET7BHG expression is observed. Does this perturbation lead to a significant difference in MIRLET7BHG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPD1 is perturbed and MIRLET7BHG expression is observed. Does this perturbation lead to a significant difference in MIRLET7BHG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94963
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SIN3A is perturbed and the expression of ENTPD7 is measured. Does this perturbation cause a significant change in ENTPD7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SIN3A is perturbed and the expression of ENTPD7 is measured. Does this perturbation cause a significant change in ENTPD7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73070
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TFAM is perturbed and VPS53 expression is observed. Does this perturbation lead to a significant difference in VPS53 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TFAM is perturbed and VPS53 expression is observed. Does this perturbation lead to a significant difference in VPS53 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1283
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STX5 is associated with a significant change in SLC25A28 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STX5 is associated with a significant change in SLC25A28 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63065
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BUD31 and examine the expression of PDCD7. Does perturbing BUD31 lead to a significant change in PDCD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BUD31 and examine the expression of PDCD7. Does perturbing BUD31 lead to a significant change in PDCD7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36591
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NSUN4 is associated with a significant change in VPS13D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NSUN4 is associated with a significant change in VPS13D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10715
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBGCP3 and examine the expression of RAB11FIP2. Does perturbing TUBGCP3 lead to a significant change in RAB11FIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TUBGCP3 and examine the expression of RAB11FIP2. Does perturbing TUBGCP3 lead to a significant change in RAB11FIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89851
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, JAZF1 is perturbed and the expression of CBLL1 is measured. Does this perturbation cause a significant change in CBLL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, JAZF1 is perturbed and the expression of CBLL1 is measured. Does this perturbation cause a significant change in CBLL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43480
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CD3EAP is perturbed and the expression of AP3S1 is measured. Determine whether AP3S1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CD3EAP is perturbed and the expression of AP3S1 is measured. Determine whether AP3S1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107506
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95280
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of TIMP1. Does perturbing NVL lead to a significant change in TIMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NVL and examine the expression of TIMP1. Does perturbing NVL lead to a significant change in TIMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92161
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HAUS1, does the expression profile of PRKAG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HAUS1, does the expression profile of PRKAG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102127
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of SAV1 is measured. Determine whether SAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of SAV1 is measured. Determine whether SAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78316
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of TIMM22 is measured. Does this perturbation cause a significant change in TIMM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of TIMM22 is measured. Does this perturbation cause a significant change in TIMM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95270
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, F8A1 is perturbed and the expression of SLC35E3 is measured. Does this perturbation cause a significant change in SLC35E3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, F8A1 is perturbed and the expression of SLC35E3 is measured. Does this perturbation cause a significant change in SLC35E3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25840
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MED21 is perturbed and the expression of UBL7 is measured. Does this perturbation cause a significant change in UBL7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MED21 is perturbed and the expression of UBL7 is measured. Does this perturbation cause a significant change in UBL7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123160
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL18A and then measure expression of COA5. Does this perturbation cause a significant change in COA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RPL18A and then measure expression of COA5. Does this perturbation cause a significant change in COA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7074
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RRP7A and then measure expression of PLK2. Does this perturbation cause a significant change in PLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RRP7A and then measure expression of PLK2. Does this perturbation cause a significant change in PLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98714
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1G1 is perturbed and LGR4 expression is measured. Determine whether LGR4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP6V1G1 is perturbed and LGR4 expression is measured. Determine whether LGR4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9679
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPSF4 is perturbed and the expression of VCPIP1 is measured. Determine whether VCPIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CPSF4 is perturbed and the expression of VCPIP1 is measured. Determine whether VCPIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111926
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPIL2 and then measure expression of POLR3D. Does this perturbation cause a significant change in POLR3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPIL2 and then measure expression of POLR3D. Does this perturbation cause a significant change in POLR3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23704
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SS18L2 is perturbed and UTP25 expression is observed. Does this perturbation lead to a significant difference in UTP25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SS18L2 is perturbed and UTP25 expression is observed. Does this perturbation lead to a significant difference in UTP25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22703
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, USP10 is perturbed and the expression of NABP2 is measured. Does this perturbation cause a significant change in NABP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, USP10 is perturbed and the expression of NABP2 is measured. Does this perturbation cause a significant change in NABP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34680
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PXN is perturbed and DTD2 expression is measured. Determine whether DTD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PXN is perturbed and DTD2 expression is measured. Determine whether DTD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48689
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AP2M1 is perturbed and EXOSC4 expression is measured. Determine whether EXOSC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AP2M1 is perturbed and EXOSC4 expression is measured. Determine whether EXOSC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18299
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOP3A is perturbed and DSTYK expression is measured. Determine whether DSTYK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOP3A is perturbed and DSTYK expression is measured. Determine whether DSTYK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103519
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MSL1 and monitor ATG9A expression. Decide whether this perturbation leads to a significant alteration in ATG9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MSL1 and monitor ATG9A expression. Decide whether this perturbation leads to a significant alteration in ATG9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112468
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CTR9 and then measure expression of PHLDA3. Does this perturbation cause a significant change in PHLDA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CTR9 and then measure expression of PHLDA3. Does this perturbation cause a significant change in PHLDA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120654
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LSM7 and monitor SCAMP2 expression. Decide whether this perturbation leads to a significant alteration in SCAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LSM7 and monitor SCAMP2 expression. Decide whether this perturbation leads to a significant alteration in SCAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93178
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BRIX1 is perturbed and RPL9 expression is observed. Does this perturbation lead to a significant difference in RPL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BRIX1 is perturbed and RPL9 expression is observed. Does this perturbation lead to a significant difference in RPL9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86613
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUB1 is perturbed and the expression of IMMT is measured. Determine whether IMMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUB1 is perturbed and the expression of IMMT is measured. Determine whether IMMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19866
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTDP1, does the expression profile of ZBTB44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CTDP1, does the expression profile of ZBTB44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31157
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRD2 and examine the expression of MAB21L2. Does perturbing BRD2 lead to a significant change in MAB21L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BRD2 and examine the expression of MAB21L2. Does perturbing BRD2 lead to a significant change in MAB21L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95751
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRCA1 is perturbed and AL627171.2 expression is measured. Determine whether AL627171.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BRCA1 is perturbed and AL627171.2 expression is measured. Determine whether AL627171.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121719
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which JMJD6 is perturbed and FRMD6-AS1 expression is observed. Does this perturbation lead to a significant difference in FRMD6-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which JMJD6 is perturbed and FRMD6-AS1 expression is observed. Does this perturbation lead to a significant difference in FRMD6-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6303
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NSRP1 and then measure expression of SERINC1. Does this perturbation cause a significant change in SERINC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NSRP1 and then measure expression of SERINC1. Does this perturbation cause a significant change in SERINC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115444
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX54 is perturbed and RANBP9 expression is measured. Determine whether RANBP9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDX54 is perturbed and RANBP9 expression is measured. Determine whether RANBP9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59709
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPP4R2 is perturbed and ZNF433-AS1 expression is observed. Does this perturbation lead to a significant difference in ZNF433-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPP4R2 is perturbed and ZNF433-AS1 expression is observed. Does this perturbation lead to a significant difference in ZNF433-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76953
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRCA1 is associated with a significant change in WASHC2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BRCA1 is associated with a significant change in WASHC2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121695
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHX15 is perturbed and SLC16A2 expression is observed. Does this perturbation lead to a significant difference in SLC16A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHX15 is perturbed and SLC16A2 expression is observed. Does this perturbation lead to a significant difference in SLC16A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97633
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PDAP1 and monitor ADAR expression. Decide whether this perturbation leads to a significant alteration in ADAR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDAP1 and monitor ADAR expression. Decide whether this perturbation leads to a significant alteration in ADAR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111658
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SKA3 is perturbed and the expression of ROBO1 is measured. Determine whether ROBO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SKA3 is perturbed and the expression of ROBO1 is measured. Determine whether ROBO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113136
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC23, does the expression profile of RSRP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDC23, does the expression profile of RSRP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100787
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPD2 is perturbed and FAS expression is measured. Determine whether FAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNRPD2 is perturbed and FAS expression is measured. Determine whether FAS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107579
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS12, does the expression profile of P4HA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS12, does the expression profile of P4HA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48117
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RPS29 and monitor CAMK1D expression. Decide whether this perturbation leads to a significant alteration in CAMK1D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RPS29 and monitor CAMK1D expression. Decide whether this perturbation leads to a significant alteration in CAMK1D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87878
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCNH and then measure expression of ALDH2. Does this perturbation cause a significant change in ALDH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCNH and then measure expression of ALDH2. Does this perturbation cause a significant change in ALDH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113264
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPP14 is perturbed and the expression of ERCC1 is measured. Determine whether ERCC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPP14 is perturbed and the expression of ERCC1 is measured. Determine whether ERCC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64176
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TAF5 is perturbed and ACO1 expression is observed. Does this perturbation lead to a significant difference in ACO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TAF5 is perturbed and ACO1 expression is observed. Does this perturbation lead to a significant difference in ACO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62663
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMNDC1 is associated with a significant change in LPIN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SMNDC1 is associated with a significant change in LPIN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63215
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSG1 and examine the expression of GNS. Does perturbing LSG1 lead to a significant change in GNS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSG1 and examine the expression of GNS. Does perturbing LSG1 lead to a significant change in GNS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99201
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NRBP1, does the expression profile of SURF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NRBP1, does the expression profile of SURF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9357
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSE1L is perturbed and MAFK expression is observed. Does this perturbation lead to a significant difference in MAFK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSE1L is perturbed and MAFK expression is observed. Does this perturbation lead to a significant difference in MAFK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21663
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UTP6 is associated with a significant change in TMEM8A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UTP6 is associated with a significant change in TMEM8A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116185
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS8 is perturbed and TBC1D2 expression is quantified. Does this perturbation result in a significant change in TBC1D2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPS8 is perturbed and TBC1D2 expression is quantified. Does this perturbation result in a significant change in TBC1D2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92922
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC2A8 and monitor GSTM3 expression. Decide whether this perturbation leads to a significant alteration in GSTM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC2A8 and monitor GSTM3 expression. Decide whether this perturbation leads to a significant alteration in GSTM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23198
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZRANB2 is perturbed and DSN1 expression is measured. Determine whether DSN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZRANB2 is perturbed and DSN1 expression is measured. Determine whether DSN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114759
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAE1 and examine the expression of F3. Does perturbing NAE1 lead to a significant change in F3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NAE1 and examine the expression of F3. Does perturbing NAE1 lead to a significant change in F3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51731
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELOB is perturbed and WASHC3 expression is quantified. Does this perturbation result in a significant change in WASHC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELOB is perturbed and WASHC3 expression is quantified. Does this perturbation result in a significant change in WASHC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11252
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS2 is perturbed and the expression of SAAL1 is measured. Does this perturbation cause a significant change in SAAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPS2 is perturbed and the expression of SAAL1 is measured. Does this perturbation cause a significant change in SAAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25030
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF39 and examine the expression of HEIH. Does perturbing PRPF39 lead to a significant change in HEIH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRPF39 and examine the expression of HEIH. Does perturbing PRPF39 lead to a significant change in HEIH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54941
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRNP1 is perturbed and PARD3 expression is quantified. Does this perturbation result in a significant change in PARD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TRNP1 is perturbed and PARD3 expression is quantified. Does this perturbation result in a significant change in PARD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99312
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOSC8 is perturbed and NCBP2AS2 expression is quantified. Does this perturbation result in a significant change in NCBP2AS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EXOSC8 is perturbed and NCBP2AS2 expression is quantified. Does this perturbation result in a significant change in NCBP2AS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115562
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CRLS1 is associated with a significant change in ZUP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CRLS1 is associated with a significant change in ZUP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97965
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDK12 is perturbed and the expression of ITGAV is measured. Determine whether ITGAV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDK12 is perturbed and the expression of ITGAV is measured. Determine whether ITGAV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103016
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CD3EAP is perturbed and the expression of RRAS is measured. Does this perturbation cause a significant change in RRAS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CD3EAP is perturbed and the expression of RRAS is measured. Does this perturbation cause a significant change in RRAS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107470
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DR1 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DR1 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121320
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLR1E is perturbed and TMEM199 expression is observed. Does this perturbation lead to a significant difference in TMEM199 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POLR1E is perturbed and TMEM199 expression is observed. Does this perturbation lead to a significant difference in TMEM199 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25823
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNRPE, does the expression profile of IGF2BP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNRPE, does the expression profile of IGF2BP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118347
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which THAP11 is perturbed and SF3B2 expression is observed. Does this perturbation lead to a significant difference in SF3B2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which THAP11 is perturbed and SF3B2 expression is observed. Does this perturbation lead to a significant difference in SF3B2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27083
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCTN2 is associated with a significant change in ZNF107 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DCTN2 is associated with a significant change in ZNF107 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83075
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAE1 and examine the expression of WDR55. Does perturbing SAE1 lead to a significant change in WDR55 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAE1 and examine the expression of WDR55. Does perturbing SAE1 lead to a significant change in WDR55 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46981
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DYNLL2 and then measure expression of DUSP4. Does this perturbation cause a significant change in DUSP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DYNLL2 and then measure expression of DUSP4. Does this perturbation cause a significant change in DUSP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69244
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS5, does the expression profile of SLC9A7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RPS5, does the expression profile of SLC9A7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59107
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO7 is perturbed and SERINC3 expression is quantified. Does this perturbation result in a significant change in SERINC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IPO7 is perturbed and SERINC3 expression is quantified. Does this perturbation result in a significant change in SERINC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52352
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BUB3 is perturbed and NANS expression is observed. Does this perturbation lead to a significant difference in NANS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BUB3 is perturbed and NANS expression is observed. Does this perturbation lead to a significant difference in NANS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42123
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNIP1 is associated with a significant change in MED10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNIP1 is associated with a significant change in MED10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70635
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NSUN4 and monitor VPS13D expression. Decide whether this perturbation leads to a significant alteration in VPS13D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NSUN4 and monitor VPS13D expression. Decide whether this perturbation leads to a significant alteration in VPS13D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10718
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RCCD1 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RCCD1 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15294
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SIRT7 and examine the expression of PFDN5. Does perturbing SIRT7 lead to a significant change in PFDN5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SIRT7 and examine the expression of PFDN5. Does perturbing SIRT7 lead to a significant change in PFDN5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22321
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NFATC2IP and then measure expression of PIP4K2A. Does this perturbation cause a significant change in PIP4K2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NFATC2IP and then measure expression of PIP4K2A. Does this perturbation cause a significant change in PIP4K2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70014
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMA16 and then measure expression of FAM214B. Does this perturbation cause a significant change in FAM214B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMA16 and then measure expression of FAM214B. Does this perturbation cause a significant change in FAM214B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100074
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNHIT6 is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNHIT6 is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97332
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RAD51C is perturbed and PAPPA expression is quantified. Does this perturbation result in a significant change in PAPPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RAD51C is perturbed and PAPPA expression is quantified. Does this perturbation result in a significant change in PAPPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105472
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5PO is perturbed and DENND5B expression is observed. Does this perturbation lead to a significant difference in DENND5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5PO is perturbed and DENND5B expression is observed. Does this perturbation lead to a significant difference in DENND5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22643
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ORC1 is perturbed and RCC2 expression is observed. Does this perturbation lead to a significant difference in RCC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ORC1 is perturbed and RCC2 expression is observed. Does this perturbation lead to a significant difference in RCC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50103
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ESF1 and examine the expression of WDR45. Does perturbing ESF1 lead to a significant change in WDR45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ESF1 and examine the expression of WDR45. Does perturbing ESF1 lead to a significant change in WDR45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39731
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLI4 and examine the expression of SDF4. Does perturbing GLI4 lead to a significant change in SDF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLI4 and examine the expression of SDF4. Does perturbing GLI4 lead to a significant change in SDF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19131
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNM1L and then measure expression of DDI2. Does this perturbation cause a significant change in DDI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNM1L and then measure expression of DDI2. Does this perturbation cause a significant change in DDI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39554
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDB1 and examine the expression of ZNF37A. Does perturbing DDB1 lead to a significant change in ZNF37A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDB1 and examine the expression of ZNF37A. Does perturbing DDB1 lead to a significant change in ZNF37A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19931
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JAZF1 is perturbed and IFT74 expression is quantified. Does this perturbation result in a significant change in IFT74 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JAZF1 is perturbed and IFT74 expression is quantified. Does this perturbation result in a significant change in IFT74 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43512
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATF5 is perturbed and the expression of MMUT is measured. Determine whether MMUT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATF5 is perturbed and the expression of MMUT is measured. Determine whether MMUT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75366
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPT16H, does the expression profile of SNRPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SUPT16H, does the expression profile of SNRPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114547
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DCTN4 and examine the expression of TENT5A. Does perturbing DCTN4 lead to a significant change in TENT5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DCTN4 and examine the expression of TENT5A. Does perturbing DCTN4 lead to a significant change in TENT5A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100201
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ROMO1, does the expression profile of ECSIT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ROMO1, does the expression profile of ECSIT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38567
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which WDR18 is perturbed and BCAS4 expression is observed. Does this perturbation lead to a significant difference in BCAS4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which WDR18 is perturbed and BCAS4 expression is observed. Does this perturbation lead to a significant difference in BCAS4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105913
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TRRAP is perturbed and ANXA6 expression is observed. Does this perturbation lead to a significant difference in ANXA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TRRAP is perturbed and ANXA6 expression is observed. Does this perturbation lead to a significant difference in ANXA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109923
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS12 is perturbed and P4HA1 expression is quantified. Does this perturbation result in a significant change in P4HA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RPS12 is perturbed and P4HA1 expression is quantified. Does this perturbation result in a significant change in P4HA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48112
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR77 and examine the expression of RIDA. Does perturbing WDR77 lead to a significant change in RIDA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDR77 and examine the expression of RIDA. Does perturbing WDR77 lead to a significant change in RIDA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48421
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SF3A2 is perturbed and PERP expression is observed. Does this perturbation lead to a significant difference in PERP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SF3A2 is perturbed and PERP expression is observed. Does this perturbation lead to a significant difference in PERP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8163
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCUN1D5 is perturbed and TUSC2 expression is quantified. Does this perturbation result in a significant change in TUSC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DCUN1D5 is perturbed and TUSC2 expression is quantified. Does this perturbation result in a significant change in TUSC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31642
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF24 is perturbed and the expression of PHACTR4 is measured. Determine whether PHACTR4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF24 is perturbed and the expression of PHACTR4 is measured. Determine whether PHACTR4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116586
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ABHD11 is perturbed and RARRES1 expression is quantified. Does this perturbation result in a significant change in RARRES1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ABHD11 is perturbed and RARRES1 expression is quantified. Does this perturbation result in a significant change in RARRES1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36772
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TRNT1 and monitor FBXO25 expression. Decide whether this perturbation leads to a significant alteration in FBXO25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TRNT1 and monitor FBXO25 expression. Decide whether this perturbation leads to a significant alteration in FBXO25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2018
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NDUFA11 and monitor STK32C expression. Decide whether this perturbation leads to a significant alteration in STK32C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NDUFA11 and monitor STK32C expression. Decide whether this perturbation leads to a significant alteration in STK32C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19778
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP2R1A and examine the expression of PBX1. Does perturbing PPP2R1A lead to a significant change in PBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPP2R1A and examine the expression of PBX1. Does perturbing PPP2R1A lead to a significant change in PBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72771
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RANBP2, does the expression profile of GGA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RANBP2, does the expression profile of GGA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86457
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COG1 and examine the expression of PNISR. Does perturbing COG1 lead to a significant change in PNISR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COG1 and examine the expression of PNISR. Does perturbing COG1 lead to a significant change in PNISR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67601
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRSF6 is perturbed and KMT2B expression is measured. Determine whether KMT2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRSF6 is perturbed and KMT2B expression is measured. Determine whether KMT2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51639
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX52 is associated with a significant change in EFEMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX52 is associated with a significant change in EFEMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105795
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGS1 and examine the expression of SESN2. Does perturbing PGS1 lead to a significant change in SESN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PGS1 and examine the expression of SESN2. Does perturbing PGS1 lead to a significant change in SESN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3621
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6AP1 is perturbed and the expression of PCSK1N is measured. Does this perturbation cause a significant change in PCSK1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP6AP1 is perturbed and the expression of PCSK1N is measured. Does this perturbation cause a significant change in PCSK1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62710
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDRG1 is perturbed and the expression of LINC00511 is measured. Determine whether LINC00511 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDRG1 is perturbed and the expression of LINC00511 is measured. Determine whether LINC00511 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65396
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DKC1 is perturbed and the expression of DCAF12 is measured. Determine whether DCAF12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DKC1 is perturbed and the expression of DCAF12 is measured. Determine whether DCAF12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74986
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCNM1 is perturbed and the expression of C12orf4 is measured. Determine whether C12orf4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCNM1 is perturbed and the expression of C12orf4 is measured. Determine whether C12orf4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57726
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MNAT1 and monitor FILIP1L expression. Decide whether this perturbation leads to a significant alteration in FILIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MNAT1 and monitor FILIP1L expression. Decide whether this perturbation leads to a significant alteration in FILIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54898
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBM8A is perturbed and Z95331.1 expression is quantified. Does this perturbation result in a significant change in Z95331.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RBM8A is perturbed and Z95331.1 expression is quantified. Does this perturbation result in a significant change in Z95331.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101542
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TRMT6 is associated with a significant change in GSTZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TRMT6 is associated with a significant change in GSTZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83375
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX59 is perturbed and BSDC1 expression is quantified. Does this perturbation result in a significant change in BSDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDX59 is perturbed and BSDC1 expression is quantified. Does this perturbation result in a significant change in BSDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6422
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHEK1 is perturbed and PEX26 expression is measured. Determine whether PEX26 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHEK1 is perturbed and PEX26 expression is measured. Determine whether PEX26 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108289
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IK, does the expression profile of AC005261.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IK, does the expression profile of AC005261.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5187
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ING3 is perturbed and the expression of LAMC1 is measured. Does this perturbation cause a significant change in LAMC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ING3 is perturbed and the expression of LAMC1 is measured. Does this perturbation cause a significant change in LAMC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47410
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LRPPRC and monitor UQCRC1 expression. Decide whether this perturbation leads to a significant alteration in UQCRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LRPPRC and monitor UQCRC1 expression. Decide whether this perturbation leads to a significant alteration in UQCRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75818
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, USF2 is perturbed and AGPS expression is quantified. Does this perturbation result in a significant change in AGPS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, USF2 is perturbed and AGPS expression is quantified. Does this perturbation result in a significant change in AGPS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105382
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of ALS2 is measured. Does this perturbation cause a significant change in ALS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ACIN1 is perturbed and the expression of ALS2 is measured. Does this perturbation cause a significant change in ALS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20710
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNF20, does the expression profile of ZMYND19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RNF20, does the expression profile of ZMYND19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85347
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KTI12 and examine the expression of ECHDC2. Does perturbing KTI12 lead to a significant change in ECHDC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KTI12 and examine the expression of ECHDC2. Does perturbing KTI12 lead to a significant change in ECHDC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58021
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP2CB is perturbed and IGBP1 expression is measured. Determine whether IGBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPP2CB is perturbed and IGBP1 expression is measured. Determine whether IGBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10129
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NELFB is perturbed and ATP5F1A expression is observed. Does this perturbation lead to a significant difference in ATP5F1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NELFB is perturbed and ATP5F1A expression is observed. Does this perturbation lead to a significant difference in ATP5F1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29983
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL34 and monitor OTUD7B expression. Decide whether this perturbation leads to a significant alteration in OTUD7B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL34 and monitor OTUD7B expression. Decide whether this perturbation leads to a significant alteration in OTUD7B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10328
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIS18BP1 is associated with a significant change in UNC119B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIS18BP1 is associated with a significant change in UNC119B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82905
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DPM2 and then measure expression of C16orf58. Does this perturbation cause a significant change in C16orf58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DPM2 and then measure expression of C16orf58. Does this perturbation cause a significant change in C16orf58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26394
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARL4D is perturbed and SOX4 expression is quantified. Does this perturbation result in a significant change in SOX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARL4D is perturbed and SOX4 expression is quantified. Does this perturbation result in a significant change in SOX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78272
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AASDHPPT and monitor DGKA expression. Decide whether this perturbation leads to a significant alteration in DGKA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AASDHPPT and monitor DGKA expression. Decide whether this perturbation leads to a significant alteration in DGKA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70358
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SCD and monitor GNB1 expression. Decide whether this perturbation leads to a significant alteration in GNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SCD and monitor GNB1 expression. Decide whether this perturbation leads to a significant alteration in GNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57538
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SHOC2 is perturbed and AC005670.3 expression is observed. Does this perturbation lead to a significant difference in AC005670.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SHOC2 is perturbed and AC005670.3 expression is observed. Does this perturbation lead to a significant difference in AC005670.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103343
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BARD1 is perturbed and the expression of SEC22B is measured. Does this perturbation cause a significant change in SEC22B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BARD1 is perturbed and the expression of SEC22B is measured. Does this perturbation cause a significant change in SEC22B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122810
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of OPA1. Does this perturbation cause a significant change in OPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of OPA1. Does this perturbation cause a significant change in OPA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14544
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP133 is perturbed and the expression of DHRS1 is measured. Determine whether DHRS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NUP133 is perturbed and the expression of DHRS1 is measured. Determine whether DHRS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17276
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTV1 and examine the expression of CDK12. Does perturbing LTV1 lead to a significant change in CDK12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LTV1 and examine the expression of CDK12. Does perturbing LTV1 lead to a significant change in CDK12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119421
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and GOLT1B expression is quantified. Does this perturbation result in a significant change in GOLT1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and GOLT1B expression is quantified. Does this perturbation result in a significant change in GOLT1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24082
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT6 and examine the expression of AC010198.2. Does perturbing TRMT6 lead to a significant change in AC010198.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TRMT6 and examine the expression of AC010198.2. Does perturbing TRMT6 lead to a significant change in AC010198.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83361
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MBD3 is perturbed and PET117 expression is measured. Determine whether PET117 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MBD3 is perturbed and PET117 expression is measured. Determine whether PET117 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76519
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHCHD4 is perturbed and the expression of C6orf120 is measured. Determine whether C6orf120 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHCHD4 is perturbed and the expression of C6orf120 is measured. Determine whether C6orf120 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27916
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCAPH is associated with a significant change in CCPG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCAPH is associated with a significant change in CCPG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24765
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS16 is perturbed and ARHGEF2 expression is observed. Does this perturbation lead to a significant difference in ARHGEF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPS16 is perturbed and ARHGEF2 expression is observed. Does this perturbation lead to a significant difference in ARHGEF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16663
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B10 is perturbed and POM121 expression is measured. Determine whether POM121 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B10 is perturbed and POM121 expression is measured. Determine whether POM121 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4719
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK1 is associated with a significant change in ROR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK1 is associated with a significant change in ROR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99285
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOC3 and examine the expression of RPS18. Does perturbing EXOC3 lead to a significant change in RPS18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EXOC3 and examine the expression of RPS18. Does perturbing EXOC3 lead to a significant change in RPS18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50471
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COTL1 is perturbed and GNB5 expression is quantified. Does this perturbation result in a significant change in GNB5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COTL1 is perturbed and GNB5 expression is quantified. Does this perturbation result in a significant change in GNB5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59932
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS26 is associated with a significant change in SQSTM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RPS26 is associated with a significant change in SQSTM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78475
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX3X is associated with a significant change in PPA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDX3X is associated with a significant change in PPA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41945
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SIN3A, does the expression profile of ENTPD7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SIN3A, does the expression profile of ENTPD7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73077
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD6 is perturbed and BAG6 expression is observed. Does this perturbation lead to a significant difference in BAG6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD6 is perturbed and BAG6 expression is observed. Does this perturbation lead to a significant difference in BAG6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78733
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PIAS4 is perturbed and FNDC3B expression is quantified. Does this perturbation result in a significant change in FNDC3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PIAS4 is perturbed and FNDC3B expression is quantified. Does this perturbation result in a significant change in FNDC3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37862
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR12 and then measure expression of NACC2. Does this perturbation cause a significant change in NACC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to WDR12 and then measure expression of NACC2. Does this perturbation cause a significant change in NACC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71794
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TUBGCP2 and monitor CYFIP2 expression. Decide whether this perturbation leads to a significant alteration in CYFIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TUBGCP2 and monitor CYFIP2 expression. Decide whether this perturbation leads to a significant alteration in CYFIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46368
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD9 is perturbed and LINC02802 expression is observed. Does this perturbation lead to a significant difference in LINC02802 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD9 is perturbed and LINC02802 expression is observed. Does this perturbation lead to a significant difference in LINC02802 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50633
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL13A is perturbed and FLYWCH2 expression is observed. Does this perturbation lead to a significant difference in FLYWCH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RPL13A is perturbed and FLYWCH2 expression is observed. Does this perturbation lead to a significant difference in FLYWCH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98863
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDX11 and monitor WWC3 expression. Decide whether this perturbation leads to a significant alteration in WWC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDX11 and monitor WWC3 expression. Decide whether this perturbation leads to a significant alteration in WWC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95038
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STRIP1 and then measure expression of KRT18. Does this perturbation cause a significant change in KRT18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STRIP1 and then measure expression of KRT18. Does this perturbation cause a significant change in KRT18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37544
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb WDR4 and monitor RGS3 expression. Decide whether this perturbation leads to a significant alteration in RGS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb WDR4 and monitor RGS3 expression. Decide whether this perturbation leads to a significant alteration in RGS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51338
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COX10 is perturbed and the expression of POLR3H is measured. Does this perturbation cause a significant change in POLR3H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COX10 is perturbed and the expression of POLR3H is measured. Does this perturbation cause a significant change in POLR3H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3020
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RARS2, does the expression profile of SCNM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RARS2, does the expression profile of SCNM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58087
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AATF is associated with a significant change in AOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AATF is associated with a significant change in AOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75325
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMG6 is perturbed and the expression of APTX is measured. Determine whether APTX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SMG6 is perturbed and the expression of APTX is measured. Determine whether APTX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53776
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM12 and examine the expression of COMMD4. Does perturbing LSM12 lead to a significant change in COMMD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LSM12 and examine the expression of COMMD4. Does perturbing LSM12 lead to a significant change in COMMD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38151
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GEMIN6 is perturbed and AGPS expression is observed. Does this perturbation lead to a significant difference in AGPS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GEMIN6 is perturbed and AGPS expression is observed. Does this perturbation lead to a significant difference in AGPS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43333
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ALG1 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ALG1 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81614
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS20 is perturbed and the expression of TNFRSF10D is measured. Determine whether TNFRSF10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RPS20 is perturbed and the expression of TNFRSF10D is measured. Determine whether TNFRSF10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84976
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KTI12 is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KTI12 is associated with a significant change in SNHG32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57995
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V0B is perturbed and UBR1 expression is observed. Does this perturbation lead to a significant difference in UBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP6V0B is perturbed and UBR1 expression is observed. Does this perturbation lead to a significant difference in UBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54413
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor NFIA expression. Decide whether this perturbation leads to a significant alteration in NFIA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor NFIA expression. Decide whether this perturbation leads to a significant alteration in NFIA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50958
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UHRF1, does the expression profile of ESCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UHRF1, does the expression profile of ESCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66787
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBMX is associated with a significant change in IFI27L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RBMX is associated with a significant change in IFI27L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37345
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZCCHC9 and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZCCHC9 and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78678
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HECTD1 is perturbed and FNIP2 expression is observed. Does this perturbation lead to a significant difference in FNIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HECTD1 is perturbed and FNIP2 expression is observed. Does this perturbation lead to a significant difference in FNIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10233
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and FUCA1 expression is quantified. Does this perturbation result in a significant change in FUCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and FUCA1 expression is quantified. Does this perturbation result in a significant change in FUCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71562
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX23, does the expression profile of OSBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDX23, does the expression profile of OSBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45477
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GINS2, does the expression profile of TTBK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GINS2, does the expression profile of TTBK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106757
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3A and examine the expression of ITGA11. Does perturbing EIF3A lead to a significant change in ITGA11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF3A and examine the expression of ITGA11. Does perturbing EIF3A lead to a significant change in ITGA11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51041
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS28 and then measure expression of FKRP. Does this perturbation cause a significant change in FKRP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to VPS28 and then measure expression of FKRP. Does this perturbation cause a significant change in FKRP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115304
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC11 and then measure expression of MAP1A. Does this perturbation cause a significant change in MAP1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TRAPPC11 and then measure expression of MAP1A. Does this perturbation cause a significant change in MAP1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88844
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP6V1A is associated with a significant change in KPNA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP6V1A is associated with a significant change in KPNA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24905
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPP2CB is associated with a significant change in IGBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPP2CB is associated with a significant change in IGBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10125
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPP14 is perturbed and MAN1A2 expression is measured. Determine whether MAN1A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RPP14 is perturbed and MAN1A2 expression is measured. Determine whether MAN1A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64189
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HPS5 is perturbed and the expression of FGF2 is measured. Determine whether FGF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HPS5 is perturbed and the expression of FGF2 is measured. Determine whether FGF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84016
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL38 is perturbed and the expression of OSBPL2 is measured. Determine whether OSBPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL38 is perturbed and the expression of OSBPL2 is measured. Determine whether OSBPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41566
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDFY3 and examine the expression of APOOL. Does perturbing WDFY3 lead to a significant change in APOOL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb WDFY3 and examine the expression of APOOL. Does perturbing WDFY3 lead to a significant change in APOOL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87211
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ANKLE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ANKLE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108495
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R7 is perturbed and the expression of HLA-B is measured. Determine whether HLA-B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPP1R7 is perturbed and the expression of HLA-B is measured. Determine whether HLA-B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14986
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PKM and examine the expression of PKD1. Does perturbing PKM lead to a significant change in PKD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PKM and examine the expression of PKD1. Does perturbing PKM lead to a significant change in PKD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43841
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUGP1 and then measure expression of NORAD. Does this perturbation cause a significant change in NORAD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SUGP1 and then measure expression of NORAD. Does this perturbation cause a significant change in NORAD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47694
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCFD1 and then measure expression of TRAPPC5. Does this perturbation cause a significant change in TRAPPC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCFD1 and then measure expression of TRAPPC5. Does this perturbation cause a significant change in TRAPPC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20344
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTBP1 and examine the expression of ZSCAN30. Does perturbing PTBP1 lead to a significant change in ZSCAN30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTBP1 and examine the expression of ZSCAN30. Does perturbing PTBP1 lead to a significant change in ZSCAN30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76171
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOE1 is perturbed and PKD2 expression is measured. Determine whether PKD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TOE1 is perturbed and PKD2 expression is measured. Determine whether PKD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54309
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC5L is associated with a significant change in ACP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDC5L is associated with a significant change in ACP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48385
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, URB1 is perturbed and TRIM5 expression is quantified. Does this perturbation result in a significant change in TRIM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, URB1 is perturbed and TRIM5 expression is quantified. Does this perturbation result in a significant change in TRIM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20992
  }
]