Update README.md
Browse files
README.md
CHANGED
|
@@ -6,6 +6,29 @@ tags:
|
|
| 6 |
- biology
|
| 7 |
- single-cell
|
| 8 |
- scFM
|
|
|
|
|
|
|
|
|
|
| 9 |
---
|
| 10 |
|
| 11 |
-
<
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 6 |
- biology
|
| 7 |
- single-cell
|
| 8 |
- scFM
|
| 9 |
+
- Drosophila
|
| 10 |
+
- foundation-model
|
| 11 |
+
- cell-type-annotation
|
| 12 |
---
|
| 13 |
|
| 14 |
+
<div align="start">
|
| 15 |
+
<img src="lemur-flaticon.png" alt="Lemur Icon" width="250">
|
| 16 |
+
<h1>Lemur: A Single-Cell Foundation Model for <em>Drosophila melanogaster</em> 🪰🔬</h1>
|
| 17 |
+
</div>
|
| 18 |
+
|
| 19 |
+
**Lemur** is a single-cell foundation model developed specifically for *Drosophila melanogaster*. It achieves fine-tuning-free cell-type annotation using two key innovations:
|
| 20 |
+
|
| 21 |
+
- **Comprehensive Pre-training:** Trained on an integrated whole-organism atlas with a unified cell-type annotation schema.
|
| 22 |
+
- **Hierarchical Decoding:** Employs a transformer-based hierarchical cell-type decoder to generate consistent predictions at multiple levels of granularity.
|
| 23 |
+
|
| 24 |
+
### Highlights
|
| 25 |
+
- **Fine-Tuning-Free Annotation:** No extra training required on new datasets.
|
| 26 |
+
- **Robust Across Conditions:** Consistent performance across various tissue types, experimental conditions, and sequencing platforms.
|
| 27 |
+
- **Zero-Shot Batch-Effect Correction:** Automatically corrects batch effects without further adjustments.
|
| 28 |
+
- **Broad Applications:** Tailored for the fly research community with potential implications for aging and neurodegenerative disease studies in humans.
|
| 29 |
+
|
| 30 |
+
### Status & Availability
|
| 31 |
+
- **Model Weights:** Available now on the Hugging Face Hub.
|
| 32 |
+
- **Code:** Will be made public alongside our preprint 📄.
|
| 33 |
+
|
| 34 |
+
Happy modeling! 🚀
|