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- ---
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- license: mit
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- ---
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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+ ---
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+ language:
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+ - en
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+ license: mit
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+ tags:
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+ - genomics
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+ - population-genetics
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+ - transformers
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+ - axial-attention
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+ - self-supervised
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+ - natural-selection
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+ - haplotype
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+ ---
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+
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+ # Popformer
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+
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+ An axial attention transformer for haplotype matrices, pre-trained with self-supervised masked haplotype reconstruction.
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+
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+ **Paper:** [Popformer: Learning general signatures of positive selection with a self-supervised transformer](https://www.biorxiv.org/content/10.64898/2026.03.06.710163v1)
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+
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+ ## Model Description
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+
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+ Popformer is pre-trained on masked haplotype reconstruction and evaluated on:
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+ - Natural selection detection
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+ - Genotype imputation
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+ - Population classification
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+
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+ ## Usage
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+
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+ See the [repository README](https://github.com/zongleon/popformer) for full preprocessing and inference examples, including VCF/HDF5 input and genome-wide selection scans.
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+
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+ ## Citation
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+ ```bibtex
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+ @article{popformer2026,
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+ title = {Popformer: Learning general signatures of positive selection with a self-supervised transformer},
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+ url = {https://www.biorxiv.org/content/10.64898/2026.03.06.710163v1}
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+ }
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+ ```