artifacts/patent_substantivity_tuple_review.jsonl

{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.98, "construct_overlap_reason": "No olfactive persistence or duration measurement is reported for a molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "The present invention relates to the field of perfumery. In particular, the compositions of the present invention have improved or enhanced fidelity and/or longevity of the fragrance profile, which is achieved by adding a specific sucrose based fragrance modulator as defined in the appended claims. Fragrance modulators do already exist, see e.g. [EP 1 186 289 A2](https://patents.google.com/patent/EP1186289A2) (TAKASAGO PERFUMERY CO LTD \\[JP\\]) 13 March 2002 (2002-03-13).", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "longevity", "scale": "numeric_unknown", "substrate": null, "time_points": null}, "regex_measured_value": "2002-03", "regex_resolved_cas": null, "regex_units": null, "source_locus": "description_translated_from:204", "verbatim_quote": "The present invention relates to the field of perfumery. In particular, the compositions of the present invention have improved or enhanced fidelity and/or longevity of the fragrance profile, which is achieved by adding a specific sucrose based fragrance modulator as defined in the appended claims. Fragrance modulators do already exist, see e.g. [EP 1 186 289 A2](https://patents.google.com/patent/EP1186289A2) (TAKASAGO PERFUMERY CO LTD \\[JP\\]) 13 March 2002 (2002-03-13)."}, "rejection_reason": "Background statement and patent citation; no single compound or measured outcome.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 1, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:204", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.96, "construct_overlap_reason": "The excerpt discusses prior fixatives but gives no measured olfactive persistence value for a molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Previous attempts to overcome these problems have been through the use of various \"fixatives\" or \"modulators\" to retard the evaporation of the more volatile fragrance ingredients present in fragrance compositions. For instance, [U.S. Patent No. 4,313,855](https://patents.google.com/patent/US4313855) (Dragoco) describes the use in cosmetic compositions of 1-(2,6,6-trimethylcyclohexyl)-hexane-3-ol as an odourless fixative for increasing the perfume's intensity. [U.S. Patent No. 6,147,049](https://patents.google.com/patent/US6147049) (Givaudan) discloses a perfume fixative derived from tera-hydronaphthalenese for use in a wide range of fragrance compositions. [U.S. Patent No. 6,440,400B1](https://patents.google.com/patent/US6440400) (Takasago Perfumery) describes a composition using trimethylcyclohexane derivatives as perfuming-holding agents and melanin-formation inhibitors. [U.S. Patent No. 6,737,396B2](https://patents.google.com/patent/US6737396) (Firmenich) describes a perfume composi", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": true, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "persistence", "scale": "percent", "substrate": ["skin"], "time_points": null}, "regex_measured_value": "2-30; 61-083114; 61-063612; 62-084010; 2014/090959; 2003/228334", "regex_resolved_cas": null, "regex_units": "ordinal_ratio", "source_locus": "description_translated_from:213", "verbatim_quote": "Previous attempts to overcome these problems have been through the use of various \"fixatives\" or \"modulators\" to retard the evaporation of the more volatile fragrance ingredients present in fragrance compositions. For instance, [U.S. Patent No. 4,313,855](https://patents.google.com/patent/US4313855) (Dragoco) describes the use in cosmetic compositions of 1-(2,6,6-trimethylcyclohexyl)-hexane-3-ol as an odourless fixative for increasing the perfume's intensity. [U.S. Patent No. 6,147,049](https://patents.google.com/patent/US6147049) (Givaudan) discloses a perfume fixative derived from tera-hydronaphthalenese for use in a wide range of fragrance compositions. [U.S. Patent No. 6,440,400B1](https://patents.google.com/patent/US6440400) (Takasago Perfumery) describes a composition using trimethylcyclohexane derivatives as perfuming-holding agents and melanin-formation inhibitors. [U.S. Patent No. 6,737,396B2](https://patents.google.com/patent/US6737396) (Firmenich) describes a perfume composition formed by mixing 2-30%, relative to the weight of the composition, of a fixative, (1-ethoxyethoxy)cyclododecane, to fix or exalt the musky or aromatic-type notes. [U.S. Patent No. 7,538,081](https://patents.google.com/patent/US7538081) (Takasago Perfumery) approaches the same problem of fixing a perfume and/or extending the perfume release from a fragrance composition. More particularly, said document describes the use of L-menthoxy ether derivatives as fixatives in fragrance compositions comprising at least one note selected from: floral, citrus, fruity, green, mint, herb and marine. JP Patent No. 61-083114 (Kanebo) describes ether derivatives as aroma-preserving agent for fine perfume composition. JP Patent No. 61-063612 (Kanebo) discloses diethylene glycol ether derivatives as fragrance adjusting agent showing effects as a fixative and a solubilizer. JP Patent No. 62-084010 (Shiseido) describes hydroquinone glycoside as perfume fixatives applicable for all kinds of perfume and blended perfume. On the other hand, PCT Publication No. WO85/04803 (Diagnostica) describes the use of hyaluronic acid/ hyaluronate as fixatives ( _via_ molecular encapsulation) in fragrance products to improve persistence of the fragrance. EP 1 186 289 describes fragrance compositions having excellent diffusivity and a long-lasting effect by incorporating a novel fixative in the composition, wherein the fixative is a 2-(L-menthoxy)alkanol derivative. EP 1 103 250 describes oil-in-polyhydric-alcohol type warming base agents containing a polyhydric alcohol, a sucrose fatty acid ester and an oil, having superior makeup removal effect, safety, stability and warming sensation. [WO 2014/090959](https://patents.google.com/patent/WO2014090959) discloses perfuming compositions that are free of ethanol in the form of transparent, clear microemulsions containing a fragrance, a solvent, non-ionic and ionic surfactants, a cooling hydrotrope and water. [US 2003/228334](https://patents.google.com/patent/US20030228334) relates to oil-in-water emulsions having a mattifying effect on the skin. The emulsions comprise a hydrophilic, non-organically modified magnesium aluminum silicate or a bentonite clay and a polyol in the water phase; and a volatile lipophilic solvent and a high melting point lipophilic plasticizer in the oil phase; and a surfactant system incuding non-toxic metal alkyl sulfates and/or sucrose esters. [DE 197 18 777](https://patents.google.com/patent/DE19718777) discloses the [...]"}, "rejection_reason": "Background citations and composition descriptions; no measured tuple for exactly one molecule.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 2, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:213", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.98, "construct_overlap_reason": "Longevity is asserted for mixtures, with no measured olfactive duration for one molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "The inventors have surprisingly discovered a revolutionary new way of objectively classifying fragrance materials and then formulating those fragrance materials into complex fragrance mixtures having improved fragrance profile fidelity and longevity. Essentially, the solution is to formulate the fragrance materials having low levels (10 to 30 wt% relative to the total weight of the fragrance materials) of the low volatile fragrance materials in the presence of a substantially non-odorous fragrance modulator to provide for improved or enhanced longevity and/or fidelity of the fragrance profile, particularly amongst characters attributable to volatile fragrance materials. In fact, the inventors have discovered that in the complete absence of the low volatile fragrance materials or at very low levels of the low volatile fragrance materials (less than 10 wt% relative to the total weight of the fragrance materials), there is insufficient character complexity and roundness of the fragrance p", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "longevity", "scale": "percent", "substrate": null, "time_points": null}, "regex_measured_value": "10 to 30", "regex_resolved_cas": null, "regex_units": null, "source_locus": "description_translated_from:240", "verbatim_quote": "The inventors have surprisingly discovered a revolutionary new way of objectively classifying fragrance materials and then formulating those fragrance materials into complex fragrance mixtures having improved fragrance profile fidelity and longevity. Essentially, the solution is to formulate the fragrance materials having low levels (10 to 30 wt% relative to the total weight of the fragrance materials) of the low volatile fragrance materials in the presence of a substantially non-odorous fragrance modulator to provide for improved or enhanced longevity and/or fidelity of the fragrance profile, particularly amongst characters attributable to volatile fragrance materials. In fact, the inventors have discovered that in the complete absence of the low volatile fragrance materials or at very low levels of the low volatile fragrance materials (less than 10 wt% relative to the total weight of the fragrance materials), there is insufficient character complexity and roundness of the fragrance profile for consumer acceptance of the composition. Therefore the level of low volatile fragrance materials needs to be carefully chosen between 10 and 30 wt% to balance consumer acceptance and the desired improved or enhanced longevity and/or fidelity of the fragrance profile, particularly amongst characters attributable to volatile fragrance materials."}, "rejection_reason": "Composition percentage range, not a measured substantivity outcome for a single compound.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 3, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:240", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.97, "construct_overlap_reason": "Although the method measures fragrance intensity over time, it is not a result for one molecule.", "construct_overlap_with_poucher": false, "evidence_quote": "50 \u00b5L samples of the compositions and the controls are applied to glass slides", "measured_property": null, "measured_value": null, "method_summary": "Compositions are applied to glass slides at 32 \u00b0C and panelists evaluate fragrance intensity or character over time.", "molecule_name": null, "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "At the testing facility, 50 \u00b5L samples of the compositions and the controls are applied to glass slides and placed on a hot plate at 32 \u00b0C to represent skin temperature for varying durations. It is important that glass slides of samples that are to be later compared are prepared at the same time. The panelists are asked to evaluate the perceived fragrance profile (intensity and/or character) of each glass slide sample at a given time point. Slides are presented coded so that their identity is not known by the panelists. Within a given time point panelists evaluate the slides in a random order and are able to revisit their assessment as they work through the slides at that time point. Their assessments are recorded. In the subsequent analysis, the data for strength and character comparisons are drawn from the independent assessments carried out at a given time point. Only when using the character difference scale below are any 2 products physically directly compared to each other. Panel", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "duration", "scale": "numeric_unknown", "substrate": ["skin"], "time_points": null}, "regex_measured_value": "6 to 10", "regex_resolved_cas": null, "regex_units": null, "source_locus": "description_translated_from:336", "verbatim_quote": "At the testing facility, 50 \u00b5L samples of the compositions and the controls are applied to glass slides and placed on a hot plate at 32 \u00b0C to represent skin temperature for varying durations. It is important that glass slides of samples that are to be later compared are prepared at the same time. The panelists are asked to evaluate the perceived fragrance profile (intensity and/or character) of each glass slide sample at a given time point. Slides are presented coded so that their identity is not known by the panelists. Within a given time point panelists evaluate the slides in a random order and are able to revisit their assessment as they work through the slides at that time point. Their assessments are recorded. In the subsequent analysis, the data for strength and character comparisons are drawn from the independent assessments carried out at a given time point. Only when using the character difference scale below are any 2 products physically directly compared to each other. Panelists are selected from individuals who are either trained to evaluate fragrances according to the scales below or who have experience with fragrance evaluation in the industry. Typically, around 6 to 10 panellists are used to evaluate a given product and its control."}, "rejection_reason": "General sensory test method for compositions and controls; no single compound identity or measured result.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 4, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:336", "substrate": "other", "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "The excerpt defines an intensity scale but reports no molecule-specific olfactive persistence measurement.", "construct_overlap_with_poucher": false, "evidence_quote": "give a score on a scale of 0 to 5 for perceived fragrance intensity", "measured_property": null, "measured_value": null, "method_summary": "Panelists score perceived fragrance intensity on a 0 to 5 odour intensity scale.", "molecule_name": null, "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "The panelists are asked to give a score on a scale of 0 to 5 for perceived fragrance intensity according to the odour intensity scale set out in Table 4 herein below. Table 4 - Odour Intensity Scale", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "fragrance_intensity", "scale": "numeric_unknown", "substrate": null, "time_points": null}, "regex_measured_value": "0 to 5", "regex_resolved_cas": null, "regex_units": null, "source_locus": "description_translated_from:338", "verbatim_quote": "The panelists are asked to give a score on a scale of 0 to 5 for perceived fragrance intensity according to the odour intensity scale set out in Table 4 herein below. Table 4 - Odour Intensity Scale"}, "rejection_reason": "Scale definition only; no compound identity or measured score.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 5, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:338", "substrate": null, "timepoint": null, "units": "scale of 0 to 5", "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.98, "construct_overlap_reason": "The excerpt lists evaporation timepoints for a method, not an olfactive persistence result for a molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "5\\. Multiple glass capillaries are prepared in the same way and left to evaporate at ambient temperature for pre-determined periods of time, such as for example 10, 15, 30 mins, 1 hr, 2 hrs, 3 hrs, 4 hrs, 5 hrs, and up to 6 hrs, before being introduced to the headspace vial and sealed.", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": "example 10", "regex_construct": {"panel_size": null, "property_name": "headspace_concentration_or_intensity", "scale": "hours_or_timepoint", "substrate": ["headspace"], "time_points": ["1 hr", "2 hrs", "3 hrs", "4 hrs", "5 hrs", "6 hrs"]}, "regex_measured_value": "1 hr; 2 hrs; 3 hrs; 4 hrs; 5 hrs; 6 hrs", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:366", "verbatim_quote": "5\\. Multiple glass capillaries are prepared in the same way and left to evaporate at ambient temperature for pre-determined periods of time, such as for example 10, 15, 30 mins, 1 hr, 2 hrs, 3 hrs, 4 hrs, 5 hrs, and up to 6 hrs, before being introduced to the headspace vial and sealed."}, "rejection_reason": "method setup only; no compound identity or measured outcome", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 6, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:366", "substrate": "headspace", "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.97, "construct_overlap_reason": "The excerpt describes panel scoring of compositions but gives no molecule-specific persistence result.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Compositions disclosed in Tables 18(a) and 19(a)-19(b) are applied to glass slides in accordance with the protocol described in the Method Section and a panel of around 6-10 experienced panelists evaluate the perceived fragrance profile at initial time 0, then at various time points, typically 1 hour, 2 hours, 3 hours, 4 hours and 6 hours post application. Panelists are asked to score the compositions for the longevity of the fragrance profile on a scale of 0 to 5, wherein 0 represents a no fragrance is detected and 5 represents a very strong fragrance intensity is detected; and for fragrance profile fidelity on a scale of 0 to 3 wherein 0 represents not detectable and 3 represents it being the dominant character. The results of the panelists are then averaged and discussed below.", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "fragrance_intensity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["1 hour", "2 hours", "3 hours", "4 hours", "6 hours"]}, "regex_measured_value": "6-10; 1 hour; 2 hours; 3 hours; 4 hours; 6 hours; 0 to 5; 0 to 3", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:440", "verbatim_quote": "Compositions disclosed in Tables 18(a) and 19(a)-19(b) are applied to glass slides in accordance with the protocol described in the Method Section and a panel of around 6-10 experienced panelists evaluate the perceived fragrance profile at initial time 0, then at various time points, typically 1 hour, 2 hours, 3 hours, 4 hours and 6 hours post application. Panelists are asked to score the compositions for the longevity of the fragrance profile on a scale of 0 to 5, wherein 0 represents a no fragrance is detected and 5 represents a very strong fragrance intensity is detected; and for fragrance profile fidelity on a scale of 0 to 3 wherein 0 represents not detectable and 3 represents it being the dominant character. The results of the panelists are then averaged and discussed below."}, "rejection_reason": "composition-level protocol; no single molecule identity or measured result", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 7, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:440", "substrate": "other", "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.9, "construct_overlap_reason": "The excerpt discusses fragrance intensity over 6 hours after application, but not as a clean molecule-only tuple.", "construct_overlap_with_poucher": true, "evidence_quote": "fragrance intensity profile of Composition R as evaluated by 10 panelists", "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": "ethyl safranate", "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Figure 1 shows the fragrance intensity profile of Composition R as evaluated by 10 panelists, which comprises the substantially non-odorous fragrance modulator sucrose myristate and the single fragrance material, ethyl safranate. Addition of the substantially non-odorous fragrance modulator maintains the intensity of the fragrance material for up to 6 hours whilst the control, Composition S, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance modulator acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 0 hours (p = 0.0015), 1hour (p = 0.0033), 3hours (p = 0.0015) and 6 hours ((p = 0.0152) all at 95% significance level ( _i.e.,_ p < 0.05).", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": 10, "property_name": "fragrance_intensity", "scale": "percent", "substrate": null, "time_points": ["6 hours", "0 hours", "1hour", "3hours"]}, "regex_measured_value": "6 hours; 0 hours; 1hour; 3hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:442", "verbatim_quote": "Figure 1 shows the fragrance intensity profile of Composition R as evaluated by 10 panelists, which comprises the substantially non-odorous fragrance modulator sucrose myristate and the single fragrance material, ethyl safranate. Addition of the substantially non-odorous fragrance modulator maintains the intensity of the fragrance material for up to 6 hours whilst the control, Composition S, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance modulator acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 0 hours (p = 0.0015), 1hour (p = 0.0033), 3hours (p = 0.0015) and 6 hours ((p = 0.0152) all at 95% significance level ( _i.e.,_ p < 0.05)."}, "rejection_reason": "composition with modulator; no numeric intensity value for the molecule", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 8, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:442", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.9, "construct_overlap_reason": "The excerpt discusses fragrance intensity over 6 hours after application, but not as a clean molecule-only tuple.", "construct_overlap_with_poucher": true, "evidence_quote": "fragrance intensity profile of Composition P as evaluated by 10 panellists", "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": "Dimethylbenzyl carbinol", "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Figure 2 shows the fragrance intensity profile of Composition P as evaluated by 10 panellists, which comprises the substantially non-odorous fragrance modulator sucrose myristate and the single fragrance material, Dimethylbenzyl carbinol. Addition of the substantially non-odorous fragrance modulator maintains the intensity of the fragrance material for up to 6 hours whilst the control, Composition Q, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance modulator acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1hour (p = 0.0581) at 90% significance level ( _i.e.,_ p < 0.1), 3hours (p = 0.0311) at 95% significance level ( _i.e.,_ p < 0.05).", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "fragrance_intensity", "scale": "percent", "substrate": null, "time_points": ["6 hours", "1hour", "3hours"]}, "regex_measured_value": "6 hours; 1hour; 3hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:443", "verbatim_quote": "Figure 2 shows the fragrance intensity profile of Composition P as evaluated by 10 panellists, which comprises the substantially non-odorous fragrance modulator sucrose myristate and the single fragrance material, Dimethylbenzyl carbinol. Addition of the substantially non-odorous fragrance modulator maintains the intensity of the fragrance material for up to 6 hours whilst the control, Composition Q, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance modulator acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1hour (p = 0.0581) at 90% significance level ( _i.e.,_ p < 0.1), 3hours (p = 0.0311) at 95% significance level ( _i.e.,_ p < 0.05)."}, "rejection_reason": "composition with modulator; no numeric intensity value for the molecule", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 9, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:443", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.91, "construct_overlap_reason": "The excerpt discusses fragrance intensity over 6 hours after application, but not as a clean molecule-only tuple.", "construct_overlap_with_poucher": true, "evidence_quote": "fragrance intensity profile of Composition T as evaluated by 10 panelists", "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": "phenethyl alcohol (PEA)", "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Figure 3 shows the fragrance intensity profile of Composition T as evaluated by 10 panelists, which comprises the substantially non-odorous fragrance modulator sucrose myristate and the single fragrance material phenethyl alcohol (PEA). Addition of the substantially non-odorous fragrance modulator maintains the intensity of the fragrance material for up to 6 hours whilst the control, Composition U, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance modulator acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1 hour (p < 0.0001), 3 hours (p = 0.0016) and 6 hours (p= 0.0003) all at 95% significance level ( _i.e.,_ p < 0.05).", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": 10, "property_name": "fragrance_intensity", "scale": "percent", "substrate": null, "time_points": ["6 hours", "1 hour", "3 hours"]}, "regex_measured_value": "6 hours; 1 hour; 3 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:444", "verbatim_quote": "Figure 3 shows the fragrance intensity profile of Composition T as evaluated by 10 panelists, which comprises the substantially non-odorous fragrance modulator sucrose myristate and the single fragrance material phenethyl alcohol (PEA). Addition of the substantially non-odorous fragrance modulator maintains the intensity of the fragrance material for up to 6 hours whilst the control, Composition U, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance modulator acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1 hour (p < 0.0001), 3 hours (p = 0.0016) and 6 hours (p= 0.0003) all at 95% significance level ( _i.e.,_ p < 0.05)."}, "rejection_reason": "composition with modulator; no numeric intensity value for the molecule", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 10, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:444", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.82, "construct_overlap_reason": "The excerpt directly concerns olfactive intensity persistence over time, but at composition level.", "construct_overlap_with_poucher": true, "evidence_quote": "fragrance intensity profile of Composition ZZ as evaluated by 11 panelists", "measured_property": "fragrance_intensity", "measured_value": null, "method_summary": "An 11-panelist fragrance intensity profile compared a modulator-containing composition with a control over 6 hours.", "molecule_name": "eugenol", "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Figure 4 shows the fragrance intensity profile of Composition ZZ as evaluated by 11 panelists, which comprises the substantially non-odorous fragrance modulator hydroquinone beta-D-glycoside and the single fragrance material, eugenol. Addition of the substantially non-odorous modulator maintains the intensity of the fragrance material for up to 6 hours whilst the control, Composition ZZZ, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance modulator acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1 hour (p = 0.0008) and 3 hours (p = 0.0123) all at 95% significance level ( _i.e.,_ p < 0.05).", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": 11, "property_name": "fragrance_intensity", "scale": "percent", "substrate": null, "time_points": ["6 hours", "1 hour", "3 hours"]}, "regex_measured_value": "6 hours; 1 hour; 3 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:445", "verbatim_quote": "Figure 4 shows the fragrance intensity profile of Composition ZZ as evaluated by 11 panelists, which comprises the substantially non-odorous fragrance modulator hydroquinone beta-D-glycoside and the single fragrance material, eugenol. Addition of the substantially non-odorous modulator maintains the intensity of the fragrance material for up to 6 hours whilst the control, Composition ZZZ, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance modulator acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1 hour (p = 0.0008) and 3 hours (p = 0.0123) all at 95% significance level ( _i.e.,_ p < 0.05)."}, "rejection_reason": "composition-level intensity profile with modulator, not a true measured tuple for one molecule alone", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 11, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:445", "substrate": null, "timepoint": "up to 6 hours", "units": "0 to 5 scale not printed in this excerpt", "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.96, "construct_overlap_reason": "No direct measured olfactive persistence value is reported for a molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": "longevity", "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "(b) Effects of the Substantially Non-Odorous Fragrance Modulators on the Fragrance Profile Longevity of Compositions having Reduced Levels of Low Volatile Fragrance Materials (between 10 to 30 wt% relative to the total weight of the Fragrance Materials) vs. Compositions having Traditional Levels of Low Volatile Fragrance Materials (Greater than 30 wt% relative to the total weight of the Fragrance Materials) and No Substantially Non-Odorous Fragrance Modulator- \\[0119\\]", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "longevity", "scale": "percent", "substrate": null, "time_points": null}, "regex_measured_value": "10 to 30", "regex_resolved_cas": null, "regex_units": null, "source_locus": "description_translated_from:446", "verbatim_quote": "(b) Effects of the Substantially Non-Odorous Fragrance Modulators on the Fragrance Profile Longevity of Compositions having Reduced Levels of Low Volatile Fragrance Materials (between 10 to 30 wt% relative to the total weight of the Fragrance Materials) vs. Compositions having Traditional Levels of Low Volatile Fragrance Materials (Greater than 30 wt% relative to the total weight of the Fragrance Materials) and No Substantially Non-Odorous Fragrance Modulator- \\[0119\\]"}, "rejection_reason": "heading/background for compositions and weight percentages, with no single compound outcome", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 12, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:446", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.95, "construct_overlap_reason": "The excerpt describes a possible sensory scale but gives no measured persistence result for a molecule.", "construct_overlap_with_poucher": false, "evidence_quote": "score the compositions for the intensity of the fragrance on a scale of 0 to 5", "measured_property": "fragrance_intensity", "measured_value": null, "method_summary": "Panelists score composition fragrance intensity on a 0 to 5 scale and results are averaged.", "molecule_name": null, "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Panelists are asked to score the compositions for the intensity of the fragrance on a scale of 0 to 5, wherein 0 represents no fragrance intensity is detected and 5 represents a very strong fragrance intensity is detected. The results of the panel test are then averaged. The results show the effect of the substantially non-odorous fragrance modulator and reduced levels of low volatile fragrance materials for any one of the inventive Compositions A, D, G, J and M on fragrance profile longevity versus control Compositions C, F, I, L and O in the absence of a substantially non-odorous modulator. Alternatively, the results show the effect of the substantially non-odorous fragrance modulator and reduced levels of low volatile fragrance materials for any one of the inventive Compositions A, D, G, J and M on fragrance profile longevity versus traditional Compositions B, E, H, K and N in the presence of the substantially non-odorous fragrance modulator.", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "fragrance_intensity", "scale": "hours_or_timepoint", "substrate": null, "time_points": null}, "regex_measured_value": "0 to 5", "regex_resolved_cas": null, "regex_units": null, "source_locus": "description_translated_from:447", "verbatim_quote": "Panelists are asked to score the compositions for the intensity of the fragrance on a scale of 0 to 5, wherein 0 represents no fragrance intensity is detected and 5 represents a very strong fragrance intensity is detected. The results of the panel test are then averaged. The results show the effect of the substantially non-odorous fragrance modulator and reduced levels of low volatile fragrance materials for any one of the inventive Compositions A, D, G, J and M on fragrance profile longevity versus control Compositions C, F, I, L and O in the absence of a substantially non-odorous modulator. Alternatively, the results show the effect of the substantially non-odorous fragrance modulator and reduced levels of low volatile fragrance materials for any one of the inventive Compositions A, D, G, J and M on fragrance profile longevity versus traditional Compositions B, E, H, K and N in the presence of the substantially non-odorous fragrance modulator."}, "rejection_reason": "method setup and scale description for compositions, with no compound identity or measured result", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 13, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:447", "substrate": null, "timepoint": null, "units": "0 to 5", "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.94, "construct_overlap_reason": "Although longevity is discussed, no direct molecule-specific measured result is provided.", "construct_overlap_with_poucher": false, "evidence_quote": "fragrance materials, particular the volatile fragrance materials", "measured_property": "longevity", "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Fragrance profile longevity, is maintained for up to at least 6 hours in the presence of the substantially non-odorous fragrance modulator whilst it drops in the absence of the substantially non-odorous fragrance modulator (data not shown). Without wishing to be bound by theory, it is believed that the substantially non-odorous fragrance modulator acts to maintain the continued evaporation over time of the fragrance materials, particular the volatile fragrance materials. The effect of the improved fragrance profile longevity of the present invention are noticeable at 1, 3 and 6 hours.", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "longevity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["6 hours"]}, "regex_measured_value": "6 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:448", "verbatim_quote": "Fragrance profile longevity, is maintained for up to at least 6 hours in the presence of the substantially non-odorous fragrance modulator whilst it drops in the absence of the substantially non-odorous fragrance modulator (data not shown). Without wishing to be bound by theory, it is believed that the substantially non-odorous fragrance modulator acts to maintain the continued evaporation over time of the fragrance materials, particular the volatile fragrance materials. The effect of the improved fragrance profile longevity of the present invention are noticeable at 1, 3 and 6 hours."}, "rejection_reason": "generic fragrance-material composition statement with data not shown and no single molecule identity", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 14, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:448", "substrate": null, "timepoint": "1, 3 and 6 hours", "units": "hours", "validation_errors": []}
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{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "No measured olfactive persistence outcome is reported for a single molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3307393B1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "17. A method to enhance the fragrance profile of a composition, preferably improve the longevity of a character, preferably a floral character, of a composition, comprising bringing into contact or mixing at least one substantially non-odorous fragrance modulator with at least one low volatile fragrance material according to a composition as defined according to any one of claims 1-16.", "patent_id": "EP3307393B1", "provenance": {"citation": "EP3307393B1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3307393B1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "longevity", "scale": "numeric_unknown", "substrate": null, "time_points": null}, "regex_measured_value": "1-16", "regex_resolved_cas": null, "regex_units": null, "source_locus": "claims_(19)_hide_dependent_translated_fr:505", "verbatim_quote": "17. A method to enhance the fragrance profile of a composition, preferably improve the longevity of a character, preferably a floral character, of a composition, comprising bringing into contact or mixing at least one substantially non-odorous fragrance modulator with at least one low volatile fragrance material according to a composition as defined according to any one of claims 1-16."}, "rejection_reason": "Method claim for a composition; no single molecule identity or measured value.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 16, "single_molecule": false, "smiles": null, "source_locus": "claims_(19)_hide_dependent_translated_fr:505", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.98, "construct_overlap_reason": "The substantivity threshold is a generic carrier criterion, not a measured olfactive duration for one molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "According to an aspect of some embodiments of the present invention there is provided a scenting concentrate comprising: cis-3-hexenol at a concentration of at least 5 weight percents of the total weight of the concentrate; an ester of cis-3-hexenol having an evaporation number higher than 50 (a \"heavy\" ester, as described herein), at a concentration of at least 5 weight percents of the total weight of the concentrate; Galbanum resinoid at a concentration of at least 3 weight percent of the total weight of the concentrate; and an alcoholic carrier comprising at least one alcohol characterized by one or more of: a boiling temperature higher than 300 \u00b0C; substantivity of at least 300 hours; and evaporation number higher than 50, relative to diethyl ether.", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "percent", "substrate": null, "time_points": ["300 hours"]}, "regex_measured_value": "300 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:107", "verbatim_quote": "According to an aspect of some embodiments of the present invention there is provided a scenting concentrate comprising: cis-3-hexenol at a concentration of at least 5 weight percents of the total weight of the concentrate; an ester of cis-3-hexenol having an evaporation number higher than 50 (a \"heavy\" ester, as described herein), at a concentration of at least 5 weight percents of the total weight of the concentrate; Galbanum resinoid at a concentration of at least 3 weight percent of the total weight of the concentrate; and an alcoholic carrier comprising at least one alcohol characterized by one or more of: a boiling temperature higher than 300 \u00b0C; substantivity of at least 300 hours; and evaporation number higher than 50, relative to diethyl ether."}, "rejection_reason": "Composition definition with concentration thresholds and generic carrier properties; no measured tuple for one molecule.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 17, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:107", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "The excerpt gives class criteria, not a direct measured persistence outcome for a molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "According to some of any of the embodiments of the present invention, the odoriferous material imparts a base note of the ligneous hay odor (substantivity higher than 100 hours, or 200 hours and/or evaporation number higher than 50).", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["100 hours", "200 hours"]}, "regex_measured_value": "100 hours; 200 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:127", "verbatim_quote": "According to some of any of the embodiments of the present invention, the odoriferous material imparts a base note of the ligneous hay odor (substantivity higher than 100 hours, or 200 hours and/or evaporation number higher than 50)."}, "rejection_reason": "Generic odoriferous material class; no named single molecule or measured result.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 18, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:127", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "The excerpt gives a generic substantivity criterion, not a measured duration for one molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "According to some of any of the embodiments of the present invention, the concentrate further comprises an odoriferous material that imparts a green or floral base note (e.g., characterized by substantivity higher than 200 hours and/or evaporation number higher than 50).", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["200 hours"]}, "regex_measured_value": "200 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:133", "verbatim_quote": "According to some of any of the embodiments of the present invention, the concentrate further comprises an odoriferous material that imparts a green or floral base note (e.g., characterized by substantivity higher than 200 hours and/or evaporation number higher than 50)."}, "rejection_reason": "Generic odoriferous material class; no named single molecule or measured result.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 19, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:133", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.98, "construct_overlap_reason": "Although scent duration is discussed, it is for a formulation rather than a single molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "The formulation disclosed herein meets a long felt need in the field of artificial grasses and grass-related artificial products, as it imparts a long-lasting grass scent to the artificial grass or product. More specifically, the formulation disclosed herein imparts a grass scent that remains for at least 2 days, preferably for at least 3 days, at least 4 days, and even for at least 5 days or more. The formulation provided herein is", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "unknown_numeric_measure", "scale": "numeric_unknown", "substrate": null, "time_points": ["2 days", "3 days", "4 days", "5 days"]}, "regex_measured_value": "2 days; 3 days; 4 days; 5 days", "regex_resolved_cas": null, "regex_units": "days", "source_locus": "description_translated_from:162", "verbatim_quote": "The formulation disclosed herein meets a long felt need in the field of artificial grasses and grass-related artificial products, as it imparts a long-lasting grass scent to the artificial grass or product. More specifically, the formulation disclosed herein imparts a grass scent that remains for at least 2 days, preferably for at least 3 days, at least 4 days, and even for at least 5 days or more. The formulation provided herein is"}, "rejection_reason": "Persistence claim for a formulation on artificial grass, not one identified molecule.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 20, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:162", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.95, "construct_overlap_reason": "The excerpt does not directly measure olfactive persistence of cis-3-hexenol alone.", "construct_overlap_with_poucher": false, "evidence_quote": "comprise additional components that contribute to maintaining the fresh grass scent for a period of at least 48 hours", "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": "cis-3-hexenol", "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "The scenting concentrate in the formulation provided herein comprises cis-3- hexenol (also known as cis-3-hexen-l-ol, and mainly as \"leaf alcohol\") as the main scenting ingredient that imparts a fresh grass scent. However, as cis-3-hexenol is a volatile compound, and features relatively low evaporation number and substantivity, the present inventors have devised and successfully prepared and practiced a concentrate and a formulation containing same, which comprise additional components that contribute to maintaining the fresh grass scent for a period of at least 48 hours.", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["48 hours"]}, "regex_measured_value": "48 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:165", "verbatim_quote": "The scenting concentrate in the formulation provided herein comprises cis-3- hexenol (also known as cis-3-hexen-l-ol, and mainly as \"leaf alcohol\") as the main scenting ingredient that imparts a fresh grass scent. However, as cis-3-hexenol is a volatile compound, and features relatively low evaporation number and substantivity, the present inventors have devised and successfully prepared and practiced a concentrate and a formulation containing same, which comprise additional components that contribute to maintaining the fresh grass scent for a period of at least 48 hours."}, "rejection_reason": "48-hour effect is for a formulation/concentrate with additional components, not a measured value for cis-3-hexenol alone.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 21, "single_molecule": true, "smiles": null, "source_locus": "description_translated_from:165", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "The excerpt defines possible duration thresholds, not a molecule-specific persistence measurement.", "construct_overlap_with_poucher": false, "evidence_quote": "By \"long-lasting scenting effect\" it is meant imparting a scent for a period longer than a few hours", "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "By \"long-lasting scenting effect\" it is meant imparting a scent for a period longer than a few hours, namely, longer than 24 hours, 37 hours, 48 hours, 60 hours, 72 hours, 84 hours, 96 hours, and even longer than 100 hours.", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "unknown_numeric_measure", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["24 hours", "37 hours", "48 hours", "60 hours", "72 hours", "84 hours", "96 hours", "100 hours"]}, "regex_measured_value": "24 hours; 37 hours; 48 hours; 60 hours; 72 hours; 84 hours; 96 hours; 100 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:170", "verbatim_quote": "By \"long-lasting scenting effect\" it is meant imparting a scent for a period longer than a few hours, namely, longer than 24 hours, 37 hours, 48 hours, 60 hours, 72 hours, 84 hours, 96 hours, and even longer than 100 hours."}, "rejection_reason": "Generic definition of long-lasting scenting effect without compound identity or measured tuple.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 22, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:170", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "The excerpt describes the construct generally but gives no molecule-specific olfactive duration measurement.", "construct_overlap_with_poucher": false, "evidence_quote": "Base notes typically have substantivity higher than 100 hours.", "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "The term \"substantivity\" is used herein and in the art of fragrances and perfumes to describe the persistence of a fragrant on the substrate to which it is applied. This term is typically reflected by the time period from application of a substance to a substrate during which the scent imparted by the substance persists, while considering conditions such as removal of the vehicle, contact with water, friction and the like. Values of substantivity provided in the art usually refer to a skin substrate, and consider also conditions to which the skin substrate is subjected to, such as sweating, swimming, bathing and the like. Substantivity of ingredients in a scenting formulation can be calculated according to methods known in the art and/or which can be found in public databases. Reference is made, for example, to www(dot)thegoodscentscompany(dot)com/data; Manuel Zarzo, Sensors, 2013, 13(l):463-483; and \"Flavor, Fragrance and Odor analysis\", Ed. Ray Marsilli, CRC Press, 29 Nov. 2001\". Bas", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "hours_or_timepoint", "substrate": ["skin"], "time_points": ["100 hours"]}, "regex_measured_value": "463-483; 100 hours; 10-100", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:174", "verbatim_quote": "The term \"substantivity\" is used herein and in the art of fragrances and perfumes to describe the persistence of a fragrant on the substrate to which it is applied. This term is typically reflected by the time period from application of a substance to a substrate during which the scent imparted by the substance persists, while considering conditions such as removal of the vehicle, contact with water, friction and the like. Values of substantivity provided in the art usually refer to a skin substrate, and consider also conditions to which the skin substrate is subjected to, such as sweating, swimming, bathing and the like. Substantivity of ingredients in a scenting formulation can be calculated according to methods known in the art and/or which can be found in public databases. Reference is made, for example, to www(dot)thegoodscentscompany(dot)com/data; Manuel Zarzo, Sensors, 2013, 13(l):463-483; and \"Flavor, Fragrance and Odor analysis\", Ed. Ray Marsilli, CRC Press, 29 Nov. 2001\". Base notes typically have substantivity higher than 100 hours. Middle notes typically have substantivity of 10-100. Top notes typically have substantivity lower than 10."}, "rejection_reason": "Background definition and citations; values are generic note-class ranges, not measured for one compound.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 23, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:174", "substrate": "skin", "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.97, "construct_overlap_reason": "The excerpt claims high substantivity for a compound class, not a measured olfactive persistence value for one molecule.", "construct_overlap_with_poucher": false, "evidence_quote": "the ester of cis-3-hexenol is characterized by substantivity higher than 100 hours, 150 hours or 200 hours", "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": "ester of cis-3-hexenol", "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "According to some of any of the embodiments of the present invention, the ester of cis-3-hexenol is a \"heavy\" ester of cis-3-hexenol, characterized by high substantivity and/or high evaporation number. In some embodiments, the ester of cis-3-hexenol is characterized by substantivity higher than 100 hours, 150 hours or 200 hours. Due to its high substantivity, such a \"heavy\" ester imparts a base note of the formulation, for example, a green, floral or grass scent base note.", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["100 hours", "150 hours", "200 hours"]}, "regex_measured_value": "100 hours; 150 hours; 200 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:180", "verbatim_quote": "According to some of any of the embodiments of the present invention, the ester of cis-3-hexenol is a \"heavy\" ester of cis-3-hexenol, characterized by high substantivity and/or high evaporation number. In some embodiments, the ester of cis-3-hexenol is characterized by substantivity higher than 100 hours, 150 hours or 200 hours. Due to its high substantivity, such a \"heavy\" ester imparts a base note of the formulation, for example, a green, floral or grass scent base note."}, "rejection_reason": "Generic class of cis-3-hexenol esters with claimed thresholds; no exact compound identity or measured method.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 24, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:180", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "The excerpt gives generic thresholds for unspecified substances, not measured olfactive persistence for one molecule.", "construct_overlap_with_poucher": false, "evidence_quote": "additional \"heavy\" substances are included in the base formulation", "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "According to some of any of the embodiments of the present invention, additional \"heavy\" substances are included in the base formulation, for imparting a long-lasting scenting effect. These substances are characterized by substantivity higher than 100 hours, or higher than 200 hours, and even higher than 300 hours, and/or by evaporation number that is higher than 50, higher than 60 or higher than 70 (or from 35 to 100 or from 50 to 100). In some embodiments, such ingredients are present in the base formulation at a concentration ranging from 1 to 10 weight percents in total, or 3 to 7 weight percents in total.", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "percent", "substrate": null, "time_points": ["100 hours", "200 hours", "300 hours"]}, "regex_measured_value": "100 hours; 200 hours; 300 hours; 35 to 100; 50 to 100; 1 to 10; 3 to 7", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:184", "verbatim_quote": "According to some of any of the embodiments of the present invention, additional \"heavy\" substances are included in the base formulation, for imparting a long-lasting scenting effect. These substances are characterized by substantivity higher than 100 hours, or higher than 200 hours, and even higher than 300 hours, and/or by evaporation number that is higher than 50, higher than 60 or higher than 70 (or from 35 to 100 or from 50 to 100). In some embodiments, such ingredients are present in the base formulation at a concentration ranging from 1 to 10 weight percents in total, or 3 to 7 weight percents in total."}, "rejection_reason": "Generic mixture/component claim with concentration ranges and thresholds; no single named compound or measured tuple.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 25, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:184", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.98, "construct_overlap_reason": "No molecule-specific olfactive persistence measurement is reported.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "In some embodiments the alcoholic base comprises one or more \"heavy alcohols\" characterized by substantivity higher than 100 hours, or higher than 200 hours or preferably higher than 300 hours, and/or by evaporation number higher than 60, higher than 70 or higher (or of from 50 to 100). Alternatively or additionally, the one or more \"heavy alcohol\" is characterized by a boiling temperature higher than 300 \u00b0C.", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["100 hours", "200 hours", "300 hours"]}, "regex_measured_value": "100 hours; 200 hours; 300 hours; 50 to 100", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:188", "verbatim_quote": "In some embodiments the alcoholic base comprises one or more \"heavy alcohols\" characterized by substantivity higher than 100 hours, or higher than 200 hours or preferably higher than 300 hours, and/or by evaporation number higher than 60, higher than 70 or higher (or of from 50 to 100). Alternatively or additionally, the one or more \"heavy alcohol\" is characterized by a boiling temperature higher than 300 \u00b0C."}, "rejection_reason": "Generic heavy alcohol class claim; no single molecule identity or measured tuple.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 26, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:188", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.98, "construct_overlap_reason": "No molecule-specific olfactive persistence measurement is reported.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "In some embodiments, such an odoriferous material is characterized by moderate to low substantivity (e.g., lower than 100 hours, or lower than 24 hours or lower than 10 hours), and/or moderate to low evaporation number (e.g., lower than 35,", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["100 hours", "24 hours", "10 hours"]}, "regex_measured_value": "100 hours; 24 hours; 10 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:198", "verbatim_quote": "In some embodiments, such an odoriferous material is characterized by moderate to low substantivity (e.g., lower than 100 hours, or lower than 24 hours or lower than 10 hours), and/or moderate to low evaporation number (e.g., lower than 35,"}, "rejection_reason": "Generic odoriferous material characterization; no single molecule identity or measured tuple.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 27, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:198", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.97, "construct_overlap_reason": "The excerpt gives class-level thresholds, not direct molecule-specific olfactive duration data.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Exemplary such odoriferous materials are aldehydes and alcohols of moderate to low substantivity (e.g., lower than 100 hours, or lower than 24 hours, or lower than 10 hours) and/or moderate to low evaporation number (e.g., lower than 35, or lower than 15, or lower than 10), such as, but not limited to, Dihydromyrcenol, Linalyle Acetate, and Styrallyl Acetate. In some embodiments, the formulation comprises one or more, or all of such odoriferous materials.", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["100 hours", "24 hours", "10 hours"]}, "regex_measured_value": "100 hours; 24 hours; 10 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:209", "verbatim_quote": "Exemplary such odoriferous materials are aldehydes and alcohols of moderate to low substantivity (e.g., lower than 100 hours, or lower than 24 hours, or lower than 10 hours) and/or moderate to low evaporation number (e.g., lower than 35, or lower than 15, or lower than 10), such as, but not limited to, Dihydromyrcenol, Linalyle Acetate, and Styrallyl Acetate. In some embodiments, the formulation comprises one or more, or all of such odoriferous materials."}, "rejection_reason": "Multiple exemplary compounds share generic threshold ranges; no measured value for exactly one molecule.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 28, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:209", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "The interval concerns formulation application scheduling, not measured olfactive persistence of a molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "As discussed hereinabove, due to the long-lasting scenting effect provided by the formulations described herein, applying the formulation to a substrate can be effected by periodic intervals of 3 days or more. Any of the methods, systems and devices described herein can therefore be employed in accordance with these time intervals. Thus, for example, a controller in an exemplary system as described herein can operate the distribution system at periodic intervals of 3 days or more. The system also comprises a data processor which can be configured to vary the time intervals employed by the controller based on a predetermined criterion or set of criteria.", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "unknown_numeric_measure", "scale": "numeric_unknown", "substrate": null, "time_points": ["3 days"]}, "regex_measured_value": "3 days", "regex_resolved_cas": null, "regex_units": "days", "source_locus": "description_translated_from:252", "verbatim_quote": "As discussed hereinabove, due to the long-lasting scenting effect provided by the formulations described herein, applying the formulation to a substrate can be effected by periodic intervals of 3 days or more. Any of the methods, systems and devices described herein can therefore be employed in accordance with these time intervals. Thus, for example, a controller in an exemplary system as described herein can operate the distribution system at periodic intervals of 3 days or more. The system also comprises a data processor which can be configured to vary the time intervals employed by the controller based on a predetermined criterion or set of criteria."}, "rejection_reason": "Formulation/system application interval claim; no single molecule or measured substantivity outcome.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 29, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:252", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "No molecule-specific olfactive persistence measurement is reported.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "substantivity of at least 300 hours; and/or", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["300 hours"]}, "regex_measured_value": "300 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "claims_()_hide_dependent_translated_from:320", "verbatim_quote": "substantivity of at least 300 hours; and/or"}, "rejection_reason": "Fragmentary claim threshold with no compound identity, method, or measured tuple.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 30, "single_molecule": false, "smiles": null, "source_locus": "claims_()_hide_dependent_translated_from:320", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.97, "construct_overlap_reason": "No olfactive persistence measurement for an identified molecule is reported.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "substantivity higher than 100 hours; and/or", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["100 hours"]}, "regex_measured_value": "100 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "claims_()_hide_dependent_translated_from:344", "verbatim_quote": "substantivity higher than 100 hours; and/or"}, "rejection_reason": "Generic claim threshold with no molecule identity or method/substrate.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 31, "single_molecule": false, "smiles": null, "source_locus": "claims_()_hide_dependent_translated_from:344", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.97, "construct_overlap_reason": "No olfactive persistence measurement for an identified molecule is reported.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "WO2016128982A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "substantivity higher than 200 hours; and/or", "patent_id": "WO2016128982A1", "provenance": {"citation": "WO2016128982A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/WO2016128982A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "substantivity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["200 hours"]}, "regex_measured_value": "200 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "claims_()_hide_dependent_translated_from:353", "verbatim_quote": "substantivity higher than 200 hours; and/or"}, "rejection_reason": "Generic claim threshold with no molecule identity or method/substrate.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 32, "single_molecule": false, "smiles": null, "source_locus": "claims_()_hide_dependent_translated_from:353", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.96, "construct_overlap_reason": "It discusses desired profile duration for compositions, not measured olfactive duration of a single molecule.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3141239A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3141239A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3141239A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "There are at least one of several drawbacks to the above described classical formulation approach. Firstly, classification of fragrance materials by their characters is subjective and therefore results in inconsistency in the fragrance profile under classical fragrance pyramid construction rules. Secondly, the perceived intensity of the fragrance profile of the conventional perfume compositions, particularly those characters attributable to the more volatile fragrance materials, decreases rapidly over time due to their quick evaporation. Accordingly, conventional perfume compositions will typically change their overall fragrance profile over time. This is a problem because it is desirable to maintain \"fragrance profile fidelity\" over time. In other words, it is desirable to maintain the same or substantively similar fragrance profile for a commercial fragrance over time, particularly over long periods of time (at least 4 hrs, 6 hrs, or even 8 hours after application). Thirdly, with the", "patent_id": "EP3141239A1", "provenance": {"citation": "EP3141239A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3141239A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "fragrance_intensity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["4 hrs", "6 hrs", "8 hours"]}, "regex_measured_value": "4 hrs; 6 hrs; 8 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:182", "verbatim_quote": "There are at least one of several drawbacks to the above described classical formulation approach. Firstly, classification of fragrance materials by their characters is subjective and therefore results in inconsistency in the fragrance profile under classical fragrance pyramid construction rules. Secondly, the perceived intensity of the fragrance profile of the conventional perfume compositions, particularly those characters attributable to the more volatile fragrance materials, decreases rapidly over time due to their quick evaporation. Accordingly, conventional perfume compositions will typically change their overall fragrance profile over time. This is a problem because it is desirable to maintain \"fragrance profile fidelity\" over time. In other words, it is desirable to maintain the same or substantively similar fragrance profile for a commercial fragrance over time, particularly over long periods of time (at least 4 hrs, 6 hrs, or even 8 hours after application). Thirdly, with the classical fragrance pyramid construction, the possible types of fragrance profiles have been somewhat limited. The consequence of using base notes at high levels is that many fragrance dry-downs appear repetitive, boring, non-memorable and uninteresting to consumers. However, if base notes are reduced or excluded then the fragrance intensity weakens over time and does not last for a sufficient duration. Lastly, it is generally accepted that some consumers desire prolonged intensity of select characters, particularly the floral, spicy or aromatic characters derived from the heart notes. Unfortunately, the consequence of using high levels of base notes is that they may impart particularly undesirable characters, such as for example, musky, woody, ambery, warm and sweet, which overpower and dominate the more desirable fragrance characters over time, particular over long periods of time. Thus, the unique challenge remains of selectively extending the more desirable characters attributable from the heart and/or top notes, particularly the heart notes, and even more particularly extending these desirable characters over long periods of time."}, "rejection_reason": "Background discussion of formulation goals, not a measured tuple for one molecule.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 33, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:182", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.96, "construct_overlap_reason": "It claims desired longevity for fragrance profiles or material classes, not a measured molecule-level persistence value.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3141239A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3141239A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3141239A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Thus, it is an advantage of the present invention to provide new rules for objectively classifying fragrance materials according to their volatility using their their vapor pressures defined at suitable temperature, instead of their characters. The new rules operate irrespective of perfumers performing the classification. In particular, the new rules classify the fragrance materials into low, moderate or high volatile fragrance materials for formulating into fragrance mixtures, particularly ones having a diamond construction. It is a further advantage of the present invention to provide compositions having improved fidelity to the perceived fragrance profile over time. It is yet a further advantage to provide a composition, wherein the character attributable to moderate and high volatile fragrance materials, particularly the moderate volatile fragrance materials, remains significantly consistent from its initial impression to the end. It is yet a further advantage to provide compositio", "patent_id": "EP3141239A1", "provenance": {"citation": "EP3141239A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3141239A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "longevity", "scale": "hours_or_timepoint", "substrate": null, "time_points": ["8 hours"]}, "regex_measured_value": "8 hours", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:191", "verbatim_quote": "Thus, it is an advantage of the present invention to provide new rules for objectively classifying fragrance materials according to their volatility using their their vapor pressures defined at suitable temperature, instead of their characters. The new rules operate irrespective of perfumers performing the classification. In particular, the new rules classify the fragrance materials into low, moderate or high volatile fragrance materials for formulating into fragrance mixtures, particularly ones having a diamond construction. It is a further advantage of the present invention to provide compositions having improved fidelity to the perceived fragrance profile over time. It is yet a further advantage to provide a composition, wherein the character attributable to moderate and high volatile fragrance materials, particularly the moderate volatile fragrance materials, remains significantly consistent from its initial impression to the end. It is yet a further advantage to provide compositions having improved longevity of the perceived fragrance profile, preferably the characters attributable from the moderate or high volatile fragrance materials, particularly the moderate volatile fragrance material. It is yet a further advantage to provide compositions having stable quality of end product ( _e.g.,_ fragrance profile, visual appearance) substantially comparable to the classical fragrance pyramid three-tiered structure, preferably even after three months storage at 40 \u00b0C. It is yet a further advantage to be able to create new to the world fragrance profiles wherein one, or several, well-recognized moderate volatile fragrance material characters, are maintained over time, preferably for long periods of time ( _e.g.,_ greater than 4, 6, or even 8 hours)."}, "rejection_reason": "Stated advantages and formulation objectives, not measured data for one molecule.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 34, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:191", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.95, "construct_overlap_reason": "Although it references panel intensity after application, it is for a composition and gives no molecule-specific measured value.", "construct_overlap_with_poucher": false, "evidence_quote": null, "measured_property": null, "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3141239A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3141239A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3141239A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "The present invention provides a method for imparting, intensifying, or modifying an odour on human skin or human hair, comprising applying to human skin and/or human hair the composition of the present invention. It is preferred that the method is for imparting, intensifying or modifying the longevity of a floral character or aromatic/spicy character on human skin or human hair, wherein the perceived intensity of the floral character or aromatic/spicy character at 1 hr, 2 hrs, 3 hrs or 6 hrs after application is greater than a control composition that does not include the substantially non-odorous fragrance modulator as determined by the panel method as disclosed herein.", "patent_id": "EP3141239A1", "provenance": {"citation": "EP3141239A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3141239A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "longevity", "scale": "hours_or_timepoint", "substrate": ["hair", "skin"], "time_points": ["1 hr", "2 hrs", "3 hrs", "6 hrs"]}, "regex_measured_value": "1 hr; 2 hrs; 3 hrs; 6 hrs", "regex_resolved_cas": null, "regex_units": "hours", "source_locus": "description_translated_from:265", "verbatim_quote": "The present invention provides a method for imparting, intensifying, or modifying an odour on human skin or human hair, comprising applying to human skin and/or human hair the composition of the present invention. It is preferred that the method is for imparting, intensifying or modifying the longevity of a floral character or aromatic/spicy character on human skin or human hair, wherein the perceived intensity of the floral character or aromatic/spicy character at 1 hr, 2 hrs, 3 hrs or 6 hrs after application is greater than a control composition that does not include the substantially non-odorous fragrance modulator as determined by the panel method as disclosed herein."}, "rejection_reason": "Generic composition/control method with no named single molecule and no numeric measured outcome.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 35, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:265", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.98, "construct_overlap_reason": "Vapor pressure is a physicochemical property, not measured olfactive persistence or intensity after application.", "construct_overlap_with_poucher": false, "evidence_quote": "Vapor Pressure (Torr at 25 \u00b0C)", "measured_property": "other", "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "EP3141239A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "EP3141239A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/EP3141239A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "| **No.** | **CAS Number** | **IUPAC Name** | **Common Name\\*\\*** | **Vapor Pressure (Torr at 25 \u00b0C)\\*** | | --- | --- | :-: | :-: | :-: | | 1. | 24168-70-5 | Pyrazine, 2-methoxy-3-(1-methylpropyl)- | Methoxyisobutylpyrazine | 0.09950000 | | 2. | 89-79-2 | Cyclohexanol, 5-methyl-2-(1-methylethenyl)-, (1 _R_, 2 _S_,5 _R_)- | Iso-Pulegol | 0.09930000 | | 3. | 112-12-9 | 2-Undecanone | Methyl Nonyl Ketone | 0.09780000 | | 4. | 103-05-9 | Benzenepropanol, \u03b1,\u03b1-dimethyl- | Phenyl Ethyl Dimethyl Carbinol | 0.09770000 | | 5. | 125-12-2 | Bicyclo\\[2.2.1\\]heptan-2-ol, 1,7,7-trimethyl-, 2-acetate, | Iso Bornyl Acetate | 0.09590000 | | | | (1 _R_,2 _R_,4 _R_)-rel- | | | | 6. | 78-70-6 | 1,6-Octadien-3-ol, 3,7-dimethyl- | Linalool | 0.09050000 | | 7. | 101-97-3 | Benzeneacetic acid, ethyl ester | Ethyl Phenyl Acetate | 0.08970000 | | 8. | 100-86-7 | Benzeneethanol, \u03b1,\u03b1-dimethyl- | Dimethyl Benzyl Carbinol | 0.08880000 | | 9. | 188570-78-7 | Cyclopropanecarboxylic acid, (3 _Z_)-3-hexen-1-yl ester |", "patent_id": "EP3141239A1", "provenance": {"citation": "EP3141239A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; 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9003-01; 9063-87; 68037-01; 63148-62; 102-71; 1 hour; 2 hours; 3 hours; 4 hours; 6 hours; 0 hours; 0 hour; 1-112; 4-6; 12-16; 22-25; 27-28; 34-37; 52-55; 69-74; 83-84; 106-108; 8-9; 12-14; 18-19; 25-28; 47-49; 53-55; 57-60; 71-73; 78-79; 84-85; 1-319; 1-130; 1-103; 1-15; 1-18", "regex_resolved_cas": "24168-70-5", "regex_units": "hours", "source_locus": "description_translated_from:284", "verbatim_quote": "| **No.** | **CAS Number** | **IUPAC Name** | **Common Name\\*\\*** | **Vapor Pressure (Torr at 25 \u00b0C)\\*** | | --- | --- | :-: | :-: | :-: | | 1. | 24168-70-5 | Pyrazine, 2-methoxy-3-(1-methylpropyl)- | Methoxyisobutylpyrazine | 0.09950000 | | 2. | 89-79-2 | Cyclohexanol, 5-methyl-2-(1-methylethenyl)-, (1 _R_, 2 _S_,5 _R_)- | Iso-Pulegol | 0.09930000 | | 3. | 112-12-9 | 2-Undecanone | Methyl Nonyl Ketone | 0.09780000 | | 4. | 103-05-9 | Benzenepropanol, \u03b1,\u03b1-dimethyl- | Phenyl Ethyl Dimethyl Carbinol | 0.09770000 | | 5. | 125-12-2 | Bicyclo\\[2.2.1\\]heptan-2-ol, 1,7,7-trimethyl-, 2-acetate, | Iso Bornyl Acetate | 0.09590000 | | | | (1 _R_,2 _R_,4 _R_)-rel- | | | | 6. | 78-70-6 | 1,6-Octadien-3-ol, 3,7-dimethyl- | Linalool | 0.09050000 | | 7. | 101-97-3 | Benzeneacetic acid, ethyl ester | Ethyl Phenyl Acetate | 0.08970000 | | 8. | 100-86-7 | Benzeneethanol, \u03b1,\u03b1-dimethyl- | Dimethyl Benzyl Carbinol | 0.08880000 | | 9. | 188570-78-7 | Cyclopropanecarboxylic acid, (3 _Z_)-3-hexen-1-yl ester | Montaverdi | 0.08640000 | | 10. | 67634-25-7 | 3-Cyclohexene-1-methanol, 3,5-dimethyl-, 1-acetate | Floralate | 0.08500000 | | 11. | 112-44-7 | Undecanal | Undecyl Aldehyde | 0.08320000 | | 12. | 32669-00-4 | Ethanone, 1-(3-cycloocten-1-yl)- | Tanaisone\u00ae | 0.08150000 | | 13. | 98-53-3 | Cyclohexanone, 4-(1,1-dimethylethyl)- | Patchi | 0.07780000 | | 14. | 35854-86-5 | 6-Nonen-1-ol, (6Z)- | cis-6-None-1-ol | 0.07770000 | | 15. | 5331-14-6 | Benzene, (2-butoxyethyl)- | Butyl phenethyl ether | 0.07760000 | | 16. | 80-57-9 | Bicycle\\[3.1.1\\]hept-3-en-2-one, 4,6,6-trimethyl- | Verbenone | 0.07730000 | | 17. | 22471-55-2 | Cyclohexanecarboxylic acid, 2,2,6-trimethyl-, ethyl ester, (1 _R_,6 _S_)-rel- | Thesaron | 0.07670000 | | 18. | 60-12-8 | Benzeneethanol | Phenethyl alcohol | 0.07410000 | | 19. | 106-26-3 | 2,6-Octadienal, 3,7-dimethyl-, (2Z)- | Neral | 0.07120000 | | 20. | 5392-40-5 | 2,6-Octadienal, 3,7-dimethyl- | Citral | 0.07120000 | | 21. | 89-48-5 | Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 1-acetate, (1 _R_,2 _S_,5 _R_)-rel- | Menthyl Acetate | 0.07070000 | | 22. | 119-36-8 | Benzoic acid, 2-hydroxy-, methyl ester | Methyl salicylate | 0.07000000 | | 23. | 4180-23-8 | Benzene, 1-methoxy-4-(1 _E_)-1-propen-1-yl- | Anethol | 0.06870000 | | 24. | 7549-37-3 | 2,6-Octadiene, 1,1-dimethoxy-3,7-dimethyl- | Citral Dimethyl Acetal | 0.06780000 | | 25. | 25225-08-5 | Cyclohexanemethanol, \u03b1, 3,3-trimethyl-, 1-formate | Aphermate | 0.06780000 | | 26. | 3913-81-3 | 2-Decenal, (2 _E_)- | 2-Decene-1-al | 0.06740000 | | 27. | 15373-31-6 | 3-Cyclopentene-1-acetonitrile, 2,2,3-trimethyl- | Cantryl\u00ae | 0.06700000 | | 28. | 6485-40-1 | 2-Cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, (5 _R_)- | Laevo carvone | 0.06560000 | | 29. | 16587-71-6 | Cyclohexanone, 4-(1,1-dimethylpropyl)- | Orivone | 0.06490000 | | 30. | 62406-73-9 | 6,10-Dioxaspiro\\[4.5\\]decane, 8,8-dimethyl-7-(1-methylethyl)- | Opalal CI | 0.06290000 | | 31. | 3720-16-9 | 2-Cyclohexen-1-one, 3-methyl-5-propyl- | Livescone | 0.06270000 | | 32. | 13816-33-6 | Benzonitrile, 4-(1-methylethyl)- | Cumin Nitrile | 0.06230000 | | 33. | 67019-89-0 | 2,6-Nonadienenitrile | Violet Nitrile | 0.06200000 | | 34. | 53398-85-9 | Butanoic acid, 2-methyl-, (3 _Z_)-3-hexen-1-yl ester | cis-3-Hexenyl Alpha Methyl Butyrate | 0.06130000 | | 35. | 208041-98-9 | n/a | Jasmonitrile | 0.05920000 | | 36. | 16510-27-3 | Benzene, 1-(cyclopropylmethyl)-4-methoxy- | Toscanol | 0.05870000 | | 37. | 111-80-8 | 2-Nonynoic acid, methyl [...]"}, "rejection_reason": "Table lists many compounds and vapor pressures, not a single-molecule substantivity measurement.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 36, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:284", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "The excerpt asserts elevated tenacity/substantivity but gives no direct measured olfactive duration or intensity value.", "construct_overlap_with_poucher": false, "evidence_quote": "compounds 1 to 8", "measured_property": "substantivity", "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "US20230126581A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "US20230126581A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/US20230126581A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Surprisingly, it was found that in particular the compounds of formula (I), and in particular compounds 1 to 8, are suitable as sandalwood-like fragrances. These compounds show additionally superior secondary properties, such as an elevated tenacity, a low odor threshold value, elevated impact (odor intensity), as well as an elevated substantivity.", "patent_id": "US20230126581A1", "provenance": {"citation": "US20230126581A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/US20230126581A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "odor_intensity", "scale": "numeric_unknown", "substrate": null, "time_points": null}, "regex_measured_value": "1 to 8", "regex_resolved_cas": null, "regex_units": null, "source_locus": "description_translated_from:212", "verbatim_quote": "Surprisingly, it was found that in particular the compounds of formula (I), and in particular compounds 1 to 8, are suitable as sandalwood-like fragrances. These compounds show additionally superior secondary properties, such as an elevated tenacity, a low odor threshold value, elevated impact (odor intensity), as well as an elevated substantivity."}, "rejection_reason": "Generic claim for compounds 1 to 8 without identity, measured value, units, substrate, or method.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 37, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:212", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "A tenacity comparison caption is not itself a measured olfactive persistence tuple.", "construct_overlap_with_poucher": false, "evidence_quote": "Comparison of the tenacity of compounds 1 to 3", "measured_property": "tenacity", "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "US20230126581A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "US20230126581A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/US20230126581A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "- | TABLE 3 | | --- | | | | Comparison of the tenacity of compounds | | 1 to 3 according to formula (I). |", "patent_id": "US20230126581A1", "provenance": {"citation": "US20230126581A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/US20230126581A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "tenacity", "scale": "numeric_unknown", "substrate": null, "time_points": null}, "regex_measured_value": "1 to 3", "regex_resolved_cas": null, "regex_units": null, "source_locus": "description_translated_from:223", "verbatim_quote": "- | TABLE 3 | | --- | | | | Comparison of the tenacity of compounds | | 1 to 3 according to formula (I). |"}, "rejection_reason": "Only a table caption; no compound identity, measured value, units, substrate, or method.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 38, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:223", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.96, "construct_overlap_reason": "The excerpt summarizes persistence and tenacity qualitatively but does not directly report a measured duration or intensity value.", "construct_overlap_with_poucher": false, "evidence_quote": "compound 3 (2-ethyl-4-[3-(methoxymethyl)-2,2-dimethyl-cyclopent-3-en-1-yl]but-2-en-1-ol)", "measured_property": "tenacity", "measured_value": null, "method_summary": null, "molecule_name": "2-ethyl-4-[3-(methoxymethyl)-2,2-dimethyl-cyclopent-3-en-1-yl]but-2-en-1-ol", "patent_id": "US20230126581A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "US20230126581A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/US20230126581A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "Therefore, among the above novel compounds specified in Table 1, compounds 1 to 4 are preferred due to their property to exhibit the most natural, the strongest and the most persistent sandalwood odor based on their high threshold intensity and superior tenacity, being superior to any existing synthetic, commercially available materials exhibiting a sandalwood odor, such as Brahmanol\u00ae (Symrise AG). However, compound 3 (2-ethyl-4-\\[3-(methoxymethyl)-2,2-dimethyl-cyclopent-3-en-1-yl\\]but-2-en-1-ol) is particularly preferred, showing the best olfactoric properties of the above indicated compounds as demonstrated in Tables 2 and 3.", "patent_id": "US20230126581A1", "provenance": {"citation": "US20230126581A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/US20230126581A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": "compound 3", "regex_construct": {"panel_size": null, "property_name": "tenacity", "scale": "numeric_unknown", "substrate": null, "time_points": null}, "regex_measured_value": "1 to 4", "regex_resolved_cas": null, "regex_units": null, "source_locus": "description_translated_from:226", "verbatim_quote": "Therefore, among the above novel compounds specified in Table 1, compounds 1 to 4 are preferred due to their property to exhibit the most natural, the strongest and the most persistent sandalwood odor based on their high threshold intensity and superior tenacity, being superior to any existing synthetic, commercially available materials exhibiting a sandalwood odor, such as Brahmanol\u00ae (Symrise AG). However, compound 3 (2-ethyl-4-\\[3-(methoxymethyl)-2,2-dimethyl-cyclopent-3-en-1-yl\\]but-2-en-1-ol) is particularly preferred, showing the best olfactoric properties of the above indicated compounds as demonstrated in Tables 2 and 3."}, "rejection_reason": "Names one compound but provides no measured value, units, substrate, or method in the excerpt.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 39, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:226", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
{"accepted_for_exploratory_tuple_set": false, "action": "reject", "cas": null, "confidence": 0.99, "construct_overlap_reason": "The excerpt claims long tenacity but does not directly measure olfactive persistence, intensity, or duration for one molecule.", "construct_overlap_with_poucher": false, "evidence_quote": "compounds 1 to 4", "measured_property": "tenacity", "measured_value": null, "method_summary": null, "molecule_name": null, "patent_id": "US20230126581A1", "poucher_overlap": {"by_cas": false, "poucher_coefficient": null, "poucher_names": null, "poucher_tier_band": null}, "provenance": {"citation": "US20230126581A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/US20230126581A1/en"}, "raw_regex_span": {"assignee": null, "method_text_verbatim": "In particular, it was found, that the compounds of formula (I) in general and in particular, compounds 1 to 4 are particularly excellent for imparting, modifying and/or enhancing a woody sandalwood-like fragrance being confusingly similar to the odor profile of natural sandalwood essential oil. The fact that the compounds have such an expressive scent and long tenacity is surprising. Furthermore, the combination of high intensity and tenacity allows for the use of said compounds and composition to achieve a pleasant odor in conjunction with an improved fixation of a fragrance compound resulting in an harmonic and long-lasting overall odor impression with the reminiscence of natural sandalwood, applicable for various perfumed products and for the production thereof.", "patent_id": "US20230126581A1", "provenance": {"citation": "US20230126581A1", "retrieval_source": "Firecrawl scrape of Google Patents public page", "tos_note": "Fetched public patent page; stored extracted spans only, not bulk full text.", "url": "https://patents.google.com/patent/US20230126581A1/en"}, "pub_date": null, "quote_truncated": false, "regex_compound_ref": null, "regex_construct": {"panel_size": null, "property_name": "tenacity", "scale": "numeric_unknown", "substrate": null, "time_points": null}, "regex_measured_value": "1 to 4", "regex_resolved_cas": null, "regex_units": null, "source_locus": "description_translated_from:316", "verbatim_quote": "In particular, it was found, that the compounds of formula (I) in general and in particular, compounds 1 to 4 are particularly excellent for imparting, modifying and/or enhancing a woody sandalwood-like fragrance being confusingly similar to the odor profile of natural sandalwood essential oil. The fact that the compounds have such an expressive scent and long tenacity is surprising. Furthermore, the combination of high intensity and tenacity allows for the use of said compounds and composition to achieve a pleasant odor in conjunction with an improved fixation of a fragrance compound resulting in an harmonic and long-lasting overall odor impression with the reminiscence of natural sandalwood, applicable for various perfumed products and for the production thereof."}, "rejection_reason": "Generic group claim for compounds 1 to 4 without single identity or measured value.", "review": {"backend": "hermes", "model": "", "policy": "accepted only when LLM finds one molecule, one measured value, evidence, and Poucher-compatible construct"}, "row_index": 40, "single_molecule": false, "smiles": null, "source_locus": "description_translated_from:316", "substrate": null, "timepoint": null, "units": null, "validation_errors": []}
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