smoke_alignment.log

2026-07-07 17:30:29,497 INFO pino.train: Training PIMT with fallback embeddings (use_fallback=True)
2026-07-07 17:30:29,498 INFO pino.train: Embedding backend: deterministic 128-bit Morgan + 10 physicochemical descriptors
2026-07-07 17:30:29,498 INFO pino.train: Device: cpu
2026-07-07 17:30:29,498 INFO pino.train: Configuration: {'hidden_dim': 256, 'num_layers': 4, 'num_heads': 4, 'batch_size': 4, 'max_batches_per_epoch': None, 'lr': 0.001, 'weight_decay': 0.01, 'checkpoint_name': 'pimt_v1.pt'}
2026-07-07 17:30:29,498 INFO pino.upload_data: Loading raw corpus from data/synthetic_dataset_v2.jsonl
2026-07-07 17:30:29,886 INFO httpx: HTTP Request: HEAD https://s3.amazonaws.com/datasets.huggingface.co/datasets/datasets/json/json.py "HTTP/1.1 200 OK"
2026-07-07 17:31:24,361 INFO pino.pimt_model: Using 15911 in-memory trajectory records
2026-07-07 17:31:29,770 INFO pino.pimt_model: Using 4089 in-memory trajectory records
2026-07-07 17:31:30,618 INFO pino.train: Batch 1 | total=37.5205 | obj=34.4277 | season=1.3922 | wear=0.8553 | alignment=0.8452
2026-07-07 17:31:30,949 INFO pino.train: Batch 2 | total=32.3926 | obj=29.4024 | season=1.7602 | wear=0.9326 | alignment=0.8126
[17:31:30] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:30] SMILES Parse Error: check for mistakes around position 2:
[17:31:30] NATURAL:8008-56-8
[17:31:30] ~^
[17:31:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:30,967 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:31:30] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:30] SMILES Parse Error: check for mistakes around position 2:
[17:31:30] NATURAL:8008-56-8
[17:31:30] ~^
[17:31:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8032-35-1
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:31,009 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8032-35-1
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:31,312 INFO pino.train: Batch 3 | total=26.9200 | obj=24.7109 | season=1.4645 | wear=0.8076 | alignment=0.7866
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8015-61-0
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:31:31,372 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8015-61-0
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8006-87-9
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:31,397 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8006-87-9
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8008-56-8
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:31,431 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8008-56-8
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:31,711 INFO pino.train: Batch 4 | total=22.6257 | obj=20.4048 | season=1.8525 | wear=0.9550 | alignment=0.7562
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8008-31-9
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:31,750 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8008-31-9
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8032-35-1
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:31,775 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:31:31] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:31] SMILES Parse Error: check for mistakes around position 2:
[17:31:31] NATURAL:8032-35-1
[17:31:31] ~^
[17:31:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:32,020 INFO pino.train: Batch 5 | total=18.0281 | obj=16.5883 | season=1.4859 | wear=0.7745 | alignment=0.7235
[17:31:32] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:32] SMILES Parse Error: check for mistakes around position 2:
[17:31:32] NATURAL:68916-26-7
[17:31:32] ~^
[17:31:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:31:32,040 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:31:32] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:32] SMILES Parse Error: check for mistakes around position 2:
[17:31:32] NATURAL:68916-26-7
[17:31:32] ~^
[17:31:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:31:32] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:32] SMILES Parse Error: check for mistakes around position 2:
[17:31:32] NATURAL:8006-80-2
[17:31:32] ~^
[17:31:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:32,090 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:31:32] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:32] SMILES Parse Error: check for mistakes around position 2:
[17:31:32] NATURAL:8006-80-2
[17:31:32] ~^
[17:31:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:31:32] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:31:32] SMILES Parse Error: check for mistakes around position 2:
[17:31:32] NATURAL:85940-31-4
[17:31:32] ~^
[17:31:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:31:32,144 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:31:32] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:31:32] SMILES Parse Error: check for mistakes around position 2:
[17:31:32] NATURAL:85940-31-4
[17:31:32] ~^
[17:31:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:31:32,409 INFO pino.train: Batch 6 | total=14.1375 | obj=12.8827 | season=1.3322 | wear=0.8149 | alignment=0.6869
[17:31:32] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:31:32] SMILES Parse Error: check for mistakes around position 2:
[17:31:32] NATURAL:85940-31-4
[17:31:32] ~^
[17:31:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:31:32,451 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:31:32] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:31:32] SMILES Parse Error: check for mistakes around position 2:
[17:31:32] NATURAL:85940-31-4
[17:31:32] ~^
[17:31:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:31:32,774 INFO pino.train: Batch 7 | total=10.9839 | obj=9.5081 | season=1.4118 | wear=0.8781 | alignment=0.6484
[17:31:32] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:32] SMILES Parse Error: check for mistakes around position 2:
[17:31:32] NATURAL:8002-73-1
[17:31:32] ~^
[17:31:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:32,794 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:32] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:32] SMILES Parse Error: check for mistakes around position 2:
[17:31:32] NATURAL:8002-73-1
[17:31:32] ~^
[17:31:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:33,062 INFO pino.train: Batch 8 | total=8.2313 | obj=6.7332 | season=1.4151 | wear=0.6874 | alignment=0.6024
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8006-87-9
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:33,091 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8006-87-9
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:33,403 INFO pino.train: Batch 9 | total=6.5436 | obj=4.5682 | season=1.5041 | wear=0.8008 | alignment=0.5366
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8002-73-1
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:33,424 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8002-73-1
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8006-87-9
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:33,473 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8006-87-9
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8002-73-1
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:33,510 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8002-73-1
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:33,700 INFO pino.train: Batch 10 | total=5.2362 | obj=2.8582 | season=1.2418 | wear=1.1612 | alignment=0.4770
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8006-87-9
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:33,727 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8006-87-9
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8008-45-5
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:33,788 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:31:33] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:33] SMILES Parse Error: check for mistakes around position 2:
[17:31:33] NATURAL:8008-45-5
[17:31:33] ~^
[17:31:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:33,991 INFO pino.train: Batch 11 | total=3.9393 | obj=1.7490 | season=1.1725 | wear=0.8566 | alignment=0.4000
[17:31:34] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:34] SMILES Parse Error: check for mistakes around position 2:
[17:31:34] NATURAL:8002-73-1
[17:31:34] ~^
[17:31:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:34,105 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:34] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:34] SMILES Parse Error: check for mistakes around position 2:
[17:31:34] NATURAL:8002-73-1
[17:31:34] ~^
[17:31:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:34,529 INFO pino.train: Batch 12 | total=3.4477 | obj=1.0405 | season=1.2447 | wear=0.8051 | alignment=0.3253
[17:31:34] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:34] SMILES Parse Error: check for mistakes around position 2:
[17:31:34] NATURAL:8008-31-9
[17:31:34] ~^
[17:31:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:34,554 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:31:34] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:34] SMILES Parse Error: check for mistakes around position 2:
[17:31:34] NATURAL:8008-31-9
[17:31:34] ~^
[17:31:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:34,968 INFO pino.train: Batch 13 | total=3.9652 | obj=0.6559 | season=1.5609 | wear=1.0919 | alignment=0.2580
[17:31:34] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:31:34] SMILES Parse Error: check for mistakes around position 2:
[17:31:34] NATURAL:8013-76-1
[17:31:34] ~^
[17:31:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:31:34,994 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:31:34] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:31:34] SMILES Parse Error: check for mistakes around position 2:
[17:31:34] NATURAL:8013-76-1
[17:31:34] ~^
[17:31:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8008-31-9
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:35,016 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8008-31-9
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8008-57-9
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:31:35,040 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8008-57-9
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:7462-86-6
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:31:35,067 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:7462-86-6
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8008-56-8
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:35,079 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8008-56-8
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8047-24-3
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:31:35,112 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8047-24-3
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8006-81-3
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:31:35,141 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8006-81-3
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:31:35,363 INFO pino.train: Batch 14 | total=3.3067 | obj=0.4544 | season=1.2559 | wear=0.9621 | alignment=0.2037
2026-07-07 17:31:35,706 INFO pino.train: Batch 15 | total=4.2073 | obj=0.3491 | season=2.0437 | wear=0.8304 | alignment=0.1681
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8008-31-9
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:35,722 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:31:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:35] SMILES Parse Error: check for mistakes around position 2:
[17:31:35] NATURAL:8008-31-9
[17:31:35] ~^
[17:31:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:36,003 INFO pino.train: Batch 16 | total=2.8164 | obj=0.2961 | season=1.1053 | wear=0.7524 | alignment=0.1448
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8002-73-1
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:36,055 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8002-73-1
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:36,263 INFO pino.train: Batch 17 | total=2.9750 | obj=0.2716 | season=1.1376 | wear=0.8178 | alignment=0.1325
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8006-87-9
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:36,316 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8006-87-9
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8006-81-3
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:31:36,338 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8006-81-3
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:31:36,540 INFO pino.train: Batch 18 | total=2.8610 | obj=0.2621 | season=1.0421 | wear=0.8098 | alignment=0.1299
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8002-73-1
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:36,564 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8002-73-1
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8002-73-1
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:36,631 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8002-73-1
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:36,822 INFO pino.train: Batch 19 | total=3.2824 | obj=0.2696 | season=1.3855 | wear=0.7232 | alignment=0.1267
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8002-73-1
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:36,852 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8002-73-1
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8015-77-8
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:31:36,887 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:31:36] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:31:36] SMILES Parse Error: check for mistakes around position 2:
[17:31:36] NATURAL:8015-77-8
[17:31:36] ~^
[17:31:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:31:37,198 INFO pino.train: Batch 20 | total=3.4608 | obj=0.2584 | season=1.4024 | wear=0.7912 | alignment=0.1228
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:8008-45-5
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:37,223 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:8008-45-5
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:8015-61-0
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:31:37,260 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:8015-61-0
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:8008-45-5
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:37,314 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:8008-45-5
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:37,572 INFO pino.train: Batch 21 | total=3.9934 | obj=0.2487 | season=1.7308 | wear=0.7556 | alignment=0.1247
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:89997-75-1
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:31:37,627 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:89997-75-1
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:8008-31-9
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:37,654 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:8008-31-9
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:85409-36-9
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:31:37,691 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:85409-36-9
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:31:37,966 INFO pino.train: Batch 22 | total=3.8350 | obj=0.2496 | season=1.5703 | wear=0.7723 | alignment=0.1224
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:8032-35-1
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:37,987 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:31:37] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:37] SMILES Parse Error: check for mistakes around position 2:
[17:31:37] NATURAL:8032-35-1
[17:31:37] ~^
[17:31:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:38,262 INFO pino.train: Batch 23 | total=3.0312 | obj=0.2520 | season=1.0704 | wear=0.7552 | alignment=0.1188
[17:31:38] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:38] SMILES Parse Error: check for mistakes around position 2:
[17:31:38] NATURAL:8008-31-9
[17:31:38] ~^
[17:31:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:38,324 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:31:38] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:38] SMILES Parse Error: check for mistakes around position 2:
[17:31:38] NATURAL:8008-31-9
[17:31:38] ~^
[17:31:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:38,513 INFO pino.train: Batch 24 | total=3.8940 | obj=0.2517 | season=1.6230 | wear=0.6930 | alignment=0.1097
2026-07-07 17:31:38,833 INFO pino.train: Batch 25 | total=3.2537 | obj=0.2479 | season=1.1361 | wear=0.7879 | alignment=0.1022
[17:31:38] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:38] SMILES Parse Error: check for mistakes around position 2:
[17:31:38] NATURAL:8002-73-1
[17:31:38] ~^
[17:31:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:38,887 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:38] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:38] SMILES Parse Error: check for mistakes around position 2:
[17:31:38] NATURAL:8002-73-1
[17:31:38] ~^
[17:31:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:39,119 INFO pino.train: Batch 26 | total=2.9580 | obj=0.2506 | season=1.0558 | wear=0.6780 | alignment=0.0801
2026-07-07 17:31:39,463 INFO pino.train: Batch 27 | total=3.9810 | obj=0.2379 | season=1.4754 | wear=0.8446 | alignment=0.0819
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8008-45-5
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:39,511 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8008-45-5
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8006-80-2
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:39,536 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8006-80-2
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:39,713 INFO pino.train: Batch 28 | total=3.5582 | obj=0.2368 | season=1.1240 | wear=0.9354 | alignment=0.0798
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8047-24-3
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:31:39,766 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8047-24-3
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8013-90-9
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:31:39,794 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8013-90-9
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8006-87-9
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:39,816 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8006-87-9
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8013-90-9
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:31:39,854 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8013-90-9
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8006-87-9
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:39,881 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:39] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:39] SMILES Parse Error: check for mistakes around position 2:
[17:31:39] NATURAL:8006-87-9
[17:31:39] ~^
[17:31:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:40,139 INFO pino.train: Batch 29 | total=3.9386 | obj=0.2345 | season=1.2803 | wear=0.9828 | alignment=0.0811
2026-07-07 17:31:40,392 INFO pino.train: Batch 30 | total=3.3963 | obj=0.2319 | season=1.1862 | wear=0.7463 | alignment=0.0858
[17:31:40] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:40] SMILES Parse Error: check for mistakes around position 2:
[17:31:40] NATURAL:68916-26-7
[17:31:40] ~^
[17:31:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:31:40,434 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:31:40] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:40] SMILES Parse Error: check for mistakes around position 2:
[17:31:40] NATURAL:68916-26-7
[17:31:40] ~^
[17:31:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:31:40] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:40] SMILES Parse Error: check for mistakes around position 2:
[17:31:40] NATURAL:8006-81-3
[17:31:40] ~^
[17:31:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:31:40,492 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:31:40] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:40] SMILES Parse Error: check for mistakes around position 2:
[17:31:40] NATURAL:8006-81-3
[17:31:40] ~^
[17:31:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
[17:31:40] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:40] SMILES Parse Error: check for mistakes around position 2:
[17:31:40] NATURAL:8008-56-8
[17:31:40] ~^
[17:31:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:40,513 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:31:40] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:40] SMILES Parse Error: check for mistakes around position 2:
[17:31:40] NATURAL:8008-56-8
[17:31:40] ~^
[17:31:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:40,726 INFO pino.train: Batch 31 | total=4.1341 | obj=0.2249 | season=1.5592 | wear=0.7746 | alignment=0.0869
[17:31:40] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:40] SMILES Parse Error: check for mistakes around position 2:
[17:31:40] NATURAL:8008-56-8
[17:31:40] ~^
[17:31:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:40,764 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:31:40] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:40] SMILES Parse Error: check for mistakes around position 2:
[17:31:40] NATURAL:8008-56-8
[17:31:40] ~^
[17:31:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:31:40] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:40] SMILES Parse Error: check for mistakes around position 2:
[17:31:40] NATURAL:8002-73-1
[17:31:40] ~^
[17:31:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:40,802 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:40] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:40] SMILES Parse Error: check for mistakes around position 2:
[17:31:40] NATURAL:8002-73-1
[17:31:40] ~^
[17:31:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:41,064 INFO pino.train: Batch 32 | total=4.4188 | obj=0.2291 | season=1.5935 | wear=0.8784 | alignment=0.0888
[17:31:41] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:41] SMILES Parse Error: check for mistakes around position 2:
[17:31:41] NATURAL:8002-73-1
[17:31:41] ~^
[17:31:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:41,109 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:41] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:41] SMILES Parse Error: check for mistakes around position 2:
[17:31:41] NATURAL:8002-73-1
[17:31:41] ~^
[17:31:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:31:41] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:31:41] SMILES Parse Error: check for mistakes around position 2:
[17:31:41] NATURAL:8015-77-8
[17:31:41] ~^
[17:31:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:31:41,132 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:31:41] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:31:41] SMILES Parse Error: check for mistakes around position 2:
[17:31:41] NATURAL:8015-77-8
[17:31:41] ~^
[17:31:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:31:41,434 INFO pino.train: Batch 33 | total=4.3957 | obj=0.2142 | season=1.6860 | wear=0.7384 | alignment=0.0889
2026-07-07 17:31:41,738 INFO pino.train: Batch 34 | total=3.6661 | obj=0.2218 | season=1.1606 | wear=0.8627 | alignment=0.0891
[17:31:41] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:41] SMILES Parse Error: check for mistakes around position 2:
[17:31:41] NATURAL:8006-87-9
[17:31:41] ~^
[17:31:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:41,781 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:41] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:41] SMILES Parse Error: check for mistakes around position 2:
[17:31:41] NATURAL:8006-87-9
[17:31:41] ~^
[17:31:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:31:41] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:41] SMILES Parse Error: check for mistakes around position 2:
[17:31:41] NATURAL:8013-90-9
[17:31:41] ~^
[17:31:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:31:41,820 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:31:41] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:41] SMILES Parse Error: check for mistakes around position 2:
[17:31:41] NATURAL:8013-90-9
[17:31:41] ~^
[17:31:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:31:42,044 INFO pino.train: Batch 35 | total=3.9773 | obj=0.2197 | season=1.4578 | wear=0.7160 | alignment=0.0890
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:85409-36-9
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:31:42,132 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:85409-36-9
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:31:42,413 INFO pino.train: Batch 36 | total=4.2685 | obj=0.2173 | season=1.5730 | wear=0.7403 | alignment=0.0901
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8006-87-9
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:42,439 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8006-87-9
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8015-61-0
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:31:42,502 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8015-61-0
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8006-87-9
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:42,526 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8006-87-9
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:42,787 INFO pino.train: Batch 37 | total=3.8852 | obj=0.2198 | season=1.2814 | wear=0.8273 | alignment=0.0897
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:7462-86-6
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:31:42,814 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:7462-86-6
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8006-80-2
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:42,831 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8006-80-2
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8006-81-3
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:31:42,869 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8006-81-3
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8002-73-1
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:42,905 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:42] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:42] SMILES Parse Error: check for mistakes around position 2:
[17:31:42] NATURAL:8002-73-1
[17:31:42] ~^
[17:31:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:43,192 INFO pino.train: Batch 38 | total=4.0219 | obj=0.2248 | season=1.4067 | wear=0.7617 | alignment=0.0897
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8002-73-1
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:43,259 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8002-73-1
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8002-73-1
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:43,293 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8002-73-1
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:43,553 INFO pino.train: Batch 39 | total=3.7585 | obj=0.2218 | season=1.2476 | wear=0.7779 | alignment=0.0896
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8013-90-9
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:31:43,603 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8013-90-9
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8006-80-2
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:43,632 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8006-80-2
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:68916-26-7
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:31:43,655 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:68916-26-7
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8013-90-9
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:31:43,685 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8013-90-9
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8006-80-2
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:43,720 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:31:43] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:43] SMILES Parse Error: check for mistakes around position 2:
[17:31:43] NATURAL:8006-80-2
[17:31:43] ~^
[17:31:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:44,003 INFO pino.train: Batch 40 | total=3.9952 | obj=0.2138 | season=1.4109 | wear=0.7285 | alignment=0.0901
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8032-35-1
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:44,036 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8032-35-1
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8002-73-1
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:44,069 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8002-73-1
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:44,240 INFO pino.train: Batch 41 | total=4.1580 | obj=0.2215 | season=1.3734 | wear=0.8560 | alignment=0.0900
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8015-61-0
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:31:44,270 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8015-61-0
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:7462-86-6
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:31:44,319 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:7462-86-6
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:31:44,574 INFO pino.train: Batch 42 | total=4.0225 | obj=0.2281 | season=1.3712 | wear=0.7761 | alignment=0.0900
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8006-87-9
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:44,595 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8006-87-9
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8006-87-9
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:44,651 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8006-87-9
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:7462-86-6
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:31:44,668 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:7462-86-6
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8032-35-1
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:44,681 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8032-35-1
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:44,954 INFO pino.train: Batch 43 | total=4.3675 | obj=0.2199 | season=1.4658 | wear=0.8631 | alignment=0.0901
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8008-56-8
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:44,974 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:31:44] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:44] SMILES Parse Error: check for mistakes around position 2:
[17:31:44] NATURAL:8008-56-8
[17:31:44] ~^
[17:31:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:45,314 INFO pino.train: Batch 44 | total=3.8875 | obj=0.2157 | season=1.2862 | wear=0.7837 | alignment=0.0897
[17:31:45] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:45] SMILES Parse Error: check for mistakes around position 2:
[17:31:45] NATURAL:8008-45-5
[17:31:45] ~^
[17:31:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:45,396 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:31:45] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:45] SMILES Parse Error: check for mistakes around position 2:
[17:31:45] NATURAL:8008-45-5
[17:31:45] ~^
[17:31:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:45,656 INFO pino.train: Batch 45 | total=4.3867 | obj=0.2134 | season=1.5486 | wear=0.7723 | alignment=0.0897
[17:31:45] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:45] SMILES Parse Error: check for mistakes around position 2:
[17:31:45] NATURAL:8002-73-1
[17:31:45] ~^
[17:31:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:45,693 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:45] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:45] SMILES Parse Error: check for mistakes around position 2:
[17:31:45] NATURAL:8002-73-1
[17:31:45] ~^
[17:31:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:45,956 INFO pino.train: Batch 46 | total=4.0608 | obj=0.2114 | season=1.2579 | wear=0.9028 | alignment=0.0898
[17:31:45] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:45] SMILES Parse Error: check for mistakes around position 2:
[17:31:45] NATURAL:8047-24-3
[17:31:45] ~^
[17:31:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:31:45,978 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:31:45] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:45] SMILES Parse Error: check for mistakes around position 2:
[17:31:45] NATURAL:8047-24-3
[17:31:45] ~^
[17:31:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:31:46,240 INFO pino.train: Batch 47 | total=3.9313 | obj=0.2169 | season=1.2908 | wear=0.7952 | alignment=0.0897
2026-07-07 17:31:46,571 INFO pino.train: Batch 48 | total=3.6789 | obj=0.2189 | season=1.1334 | wear=0.8224 | alignment=0.0894
[17:31:46] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:46] SMILES Parse Error: check for mistakes around position 2:
[17:31:46] NATURAL:8006-80-2
[17:31:46] ~^
[17:31:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:46,590 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:31:46] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:46] SMILES Parse Error: check for mistakes around position 2:
[17:31:46] NATURAL:8006-80-2
[17:31:46] ~^
[17:31:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:31:46] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:46] SMILES Parse Error: check for mistakes around position 2:
[17:31:46] NATURAL:85409-36-9
[17:31:46] ~^
[17:31:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:31:46,615 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:31:46] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:46] SMILES Parse Error: check for mistakes around position 2:
[17:31:46] NATURAL:85409-36-9
[17:31:46] ~^
[17:31:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:31:46,841 INFO pino.train: Batch 49 | total=4.5119 | obj=0.2097 | season=1.6472 | wear=0.7301 | alignment=0.0895
[17:31:46] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:46] SMILES Parse Error: check for mistakes around position 2:
[17:31:46] NATURAL:8002-73-1
[17:31:46] ~^
[17:31:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:46,869 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:46] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:46] SMILES Parse Error: check for mistakes around position 2:
[17:31:46] NATURAL:8002-73-1
[17:31:46] ~^
[17:31:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:47,123 INFO pino.train: Batch 50 | total=4.1273 | obj=0.2082 | season=1.4177 | wear=0.7555 | alignment=0.0890
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8013-90-9
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:31:47,161 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8013-90-9
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8047-24-3
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:31:47,189 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8047-24-3
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8002-73-1
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:47,219 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8002-73-1
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8006-81-3
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:31:47,241 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8006-81-3
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8015-61-0
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:31:47,272 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8015-61-0
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:85409-36-9
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:31:47,311 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:85409-36-9
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:31:47,595 INFO pino.train: Batch 51 | total=3.5539 | obj=0.2204 | season=1.1719 | wear=0.7008 | alignment=0.0888
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8008-31-9
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:47,658 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8008-31-9
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:47,940 INFO pino.train: Batch 52 | total=4.2439 | obj=0.2107 | season=1.4457 | wear=0.7860 | alignment=0.0886
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8008-57-9
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:31:47,976 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:31:47] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:31:47] SMILES Parse Error: check for mistakes around position 2:
[17:31:47] NATURAL:8008-57-9
[17:31:47] ~^
[17:31:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8002-73-1
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:48,019 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8002-73-1
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:48,233 INFO pino.train: Batch 53 | total=3.6508 | obj=0.2137 | season=1.2080 | wear=0.7124 | alignment=0.0888
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8032-35-1
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:48,283 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8032-35-1
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8015-61-0
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:31:48,313 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8015-61-0
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:31:48,548 INFO pino.train: Batch 54 | total=4.3825 | obj=0.2112 | season=1.5159 | wear=0.7807 | alignment=0.0882
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8015-77-8
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:31:48,594 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8015-77-8
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8008-45-5
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:48,617 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8008-45-5
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:48,947 INFO pino.train: Batch 55 | total=4.8865 | obj=0.2083 | season=1.7453 | wear=0.7960 | alignment=0.0870
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8002-73-1
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:48,987 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:48] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:48] SMILES Parse Error: check for mistakes around position 2:
[17:31:48] NATURAL:8002-73-1
[17:31:48] ~^
[17:31:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:49,236 INFO pino.train: Batch 56 | total=3.4599 | obj=0.2118 | season=1.0391 | wear=0.7812 | alignment=0.0844
[17:31:49] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:49] SMILES Parse Error: check for mistakes around position 2:
[17:31:49] NATURAL:8008-45-5
[17:31:49] ~^
[17:31:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:49,263 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:31:49] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:49] SMILES Parse Error: check for mistakes around position 2:
[17:31:49] NATURAL:8008-45-5
[17:31:49] ~^
[17:31:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:31:49] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:49] SMILES Parse Error: check for mistakes around position 2:
[17:31:49] NATURAL:8015-61-0
[17:31:49] ~^
[17:31:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:31:49,328 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:31:49] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:49] SMILES Parse Error: check for mistakes around position 2:
[17:31:49] NATURAL:8015-61-0
[17:31:49] ~^
[17:31:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:31:49,635 INFO pino.train: Batch 57 | total=4.3624 | obj=0.2073 | season=1.3174 | wear=0.9824 | alignment=0.0843
[17:31:49] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:31:49] SMILES Parse Error: check for mistakes around position 2:
[17:31:49] NATURAL:8008-57-9
[17:31:49] ~^
[17:31:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:31:49,649 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:31:49] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:31:49] SMILES Parse Error: check for mistakes around position 2:
[17:31:49] NATURAL:8008-57-9
[17:31:49] ~^
[17:31:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:31:49] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:49] SMILES Parse Error: check for mistakes around position 2:
[17:31:49] NATURAL:8006-80-2
[17:31:49] ~^
[17:31:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:49,714 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:31:49] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:49] SMILES Parse Error: check for mistakes around position 2:
[17:31:49] NATURAL:8006-80-2
[17:31:49] ~^
[17:31:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:49,989 INFO pino.train: Batch 58 | total=3.6766 | obj=0.2007 | season=1.2241 | wear=0.7065 | alignment=0.0774
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8013-76-1
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:31:50,042 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8013-76-1
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:31:50,280 INFO pino.train: Batch 59 | total=3.8756 | obj=0.2080 | season=1.2416 | wear=0.7968 | alignment=0.0658
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8002-73-1
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:50,302 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8002-73-1
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8008-56-8
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:50,370 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8008-56-8
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8006-87-9
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:50,397 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8006-87-9
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8006-81-3
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:31:50,421 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8006-81-3
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:31:50,651 INFO pino.train: Batch 60 | total=3.6917 | obj=0.2133 | season=1.1692 | wear=0.7725 | alignment=0.0408
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:85409-36-9
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:31:50,698 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:85409-36-9
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8002-73-1
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:50,721 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:50] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:50] SMILES Parse Error: check for mistakes around position 2:
[17:31:50] NATURAL:8002-73-1
[17:31:50] ~^
[17:31:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:31:51] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:51] SMILES Parse Error: check for mistakes around position 2:
[17:31:51] NATURAL:8008-45-5
[17:31:51] ~^
[17:31:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:51,484 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:31:51] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:51] SMILES Parse Error: check for mistakes around position 2:
[17:31:51] NATURAL:8008-45-5
[17:31:51] ~^
[17:31:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:31:51] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:51] SMILES Parse Error: check for mistakes around position 2:
[17:31:51] NATURAL:8032-35-1
[17:31:51] ~^
[17:31:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:51,510 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:31:51] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:51] SMILES Parse Error: check for mistakes around position 2:
[17:31:51] NATURAL:8032-35-1
[17:31:51] ~^
[17:31:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:31:51] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:31:51] SMILES Parse Error: check for mistakes around position 2:
[17:31:51] NATURAL:8008-57-9
[17:31:51] ~^
[17:31:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:31:51,542 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:31:51] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:31:51] SMILES Parse Error: check for mistakes around position 2:
[17:31:51] NATURAL:8008-57-9
[17:31:51] ~^
[17:31:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:31:51] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:51] SMILES Parse Error: check for mistakes around position 2:
[17:31:51] NATURAL:8008-31-9
[17:31:51] ~^
[17:31:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:51,566 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:31:51] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:31:51] SMILES Parse Error: check for mistakes around position 2:
[17:31:51] NATURAL:8008-31-9
[17:31:51] ~^
[17:31:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:31:51,828 INFO pino.train: Batch 61 | total=4.5378 | obj=0.2120 | season=1.6140 | wear=0.7493 | alignment=0.0284
2026-07-07 17:31:52,171 INFO pino.train: Batch 62 | total=4.5264 | obj=0.2093 | season=1.5718 | wear=0.7718 | alignment=0.0225
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:8006-80-2
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:52,200 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:8006-80-2
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:52,476 INFO pino.train: Batch 63 | total=3.8211 | obj=0.2082 | season=1.1869 | wear=0.7986 | alignment=0.0149
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:89997-75-1
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:31:52,525 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:89997-75-1
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:8006-80-2
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:52,550 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:8006-80-2
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:52,829 INFO pino.train: Batch 64 | total=3.9556 | obj=0.2066 | season=1.1968 | wear=0.8578 | alignment=0.0208
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:8002-73-1
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:52,858 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:8002-73-1
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:8008-56-8
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:52,898 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:8008-56-8
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:8002-73-1
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:52,918 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:52] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:52] SMILES Parse Error: check for mistakes around position 2:
[17:31:52] NATURAL:8002-73-1
[17:31:52] ~^
[17:31:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:53,162 INFO pino.train: Batch 65 | total=3.8981 | obj=0.2123 | season=1.2036 | wear=0.8181 | alignment=0.0287
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:8002-73-1
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:53,187 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:8002-73-1
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:53,404 INFO pino.train: Batch 66 | total=3.8680 | obj=0.2054 | season=1.2690 | wear=0.7309 | alignment=0.0271
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:8002-73-1
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:53,467 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:8002-73-1
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:53,727 INFO pino.train: Batch 67 | total=4.7585 | obj=0.2060 | season=1.6595 | wear=0.7816 | alignment=0.0289
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:8002-73-1
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:53,751 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:8002-73-1
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:7462-86-6
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:31:53,773 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:7462-86-6
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:8013-90-9
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:31:53,795 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:8013-90-9
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:8006-81-3
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:31:53,837 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:31:53] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:31:53] SMILES Parse Error: check for mistakes around position 2:
[17:31:53] NATURAL:8006-81-3
[17:31:53] ~^
[17:31:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:31:54,044 INFO pino.train: Batch 68 | total=3.8130 | obj=0.2103 | season=1.2677 | wear=0.6867 | alignment=0.0284
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:8032-35-1
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:54,058 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:8032-35-1
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:8006-80-2
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:54,119 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:8006-80-2
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:89997-75-1
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:31:54,157 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:89997-75-1
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:31:54,445 INFO pino.train: Batch 69 | total=4.8089 | obj=0.2101 | season=1.6448 | wear=0.8055 | alignment=0.0287
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:68916-26-7
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:31:54,489 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:68916-26-7
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:8006-87-9
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:54,518 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:8006-87-9
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:54,830 INFO pino.train: Batch 70 | total=4.2862 | obj=0.2133 | season=1.3851 | wear=0.8027 | alignment=0.0292
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:8008-45-5
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:31:54,866 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:8008-45-5
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:8013-90-9
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:31:54,892 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:31:54] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:31:54] SMILES Parse Error: check for mistakes around position 2:
[17:31:54] NATURAL:8013-90-9
[17:31:54] ~^
[17:31:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:31:55,085 INFO pino.train: Batch 71 | total=4.0946 | obj=0.2073 | season=1.2109 | wear=0.8898 | alignment=0.0271
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:8002-73-1
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:55,120 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:8002-73-1
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:55,337 INFO pino.train: Batch 72 | total=3.9070 | obj=0.2195 | season=1.2004 | wear=0.8022 | alignment=0.0275
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:85409-36-9
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:31:55,363 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:85409-36-9
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:31:55,659 INFO pino.train: Batch 73 | total=3.7622 | obj=0.2148 | season=1.1828 | wear=0.7442 | alignment=0.0264
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:8013-76-1
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:31:55,685 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:8013-76-1
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:31:55,923 INFO pino.train: Batch 74 | total=4.3343 | obj=0.2063 | season=1.4699 | wear=0.7383 | alignment=0.0244
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:7462-86-6
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:31:55,928 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:7462-86-6
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:8015-61-0
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:31:55,946 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:8015-61-0
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:8002-73-1
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:55,988 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:55] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:55] SMILES Parse Error: check for mistakes around position 2:
[17:31:55] NATURAL:8002-73-1
[17:31:55] ~^
[17:31:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:31:56] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:56] SMILES Parse Error: check for mistakes around position 2:
[17:31:56] NATURAL:8008-56-8
[17:31:56] ~^
[17:31:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:56,021 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:31:56] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:56] SMILES Parse Error: check for mistakes around position 2:
[17:31:56] NATURAL:8008-56-8
[17:31:56] ~^
[17:31:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:56,254 INFO pino.train: Batch 75 | total=4.8288 | obj=0.2102 | season=1.6490 | wear=0.7985 | alignment=0.0229
[17:31:56] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:56] SMILES Parse Error: check for mistakes around position 2:
[17:31:56] NATURAL:68916-26-7
[17:31:56] ~^
[17:31:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:31:56,302 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:31:56] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:56] SMILES Parse Error: check for mistakes around position 2:
[17:31:56] NATURAL:68916-26-7
[17:31:56] ~^
[17:31:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:31:56,490 INFO pino.train: Batch 76 | total=3.9470 | obj=0.2191 | season=1.1865 | wear=0.8274 | alignment=0.0272
[17:31:56] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:56] SMILES Parse Error: check for mistakes around position 2:
[17:31:56] NATURAL:8047-24-3
[17:31:56] ~^
[17:31:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:31:56,526 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:31:56] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:56] SMILES Parse Error: check for mistakes around position 2:
[17:31:56] NATURAL:8047-24-3
[17:31:56] ~^
[17:31:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:31:56] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:56] SMILES Parse Error: check for mistakes around position 2:
[17:31:56] NATURAL:68916-26-7
[17:31:56] ~^
[17:31:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:31:56,560 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:31:56] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:31:56] SMILES Parse Error: check for mistakes around position 2:
[17:31:56] NATURAL:68916-26-7
[17:31:56] ~^
[17:31:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:31:56,690 INFO pino.train: Batch 77 | total=4.3293 | obj=0.2153 | season=1.4590 | wear=0.7361 | alignment=0.0380
[17:31:56] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:31:56] SMILES Parse Error: check for mistakes around position 2:
[17:31:56] NATURAL:8013-76-1
[17:31:56] ~^
[17:31:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:31:56,715 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:31:56] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:31:56] SMILES Parse Error: check for mistakes around position 2:
[17:31:56] NATURAL:8013-76-1
[17:31:56] ~^
[17:31:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:31:57,002 INFO pino.train: Batch 78 | total=4.8418 | obj=0.2132 | season=1.6335 | wear=0.8131 | alignment=0.0256
2026-07-07 17:31:57,303 INFO pino.train: Batch 79 | total=4.3179 | obj=0.2027 | season=1.4443 | wear=0.7330 | alignment=0.0258
[17:31:57] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:57] SMILES Parse Error: check for mistakes around position 2:
[17:31:57] NATURAL:8047-24-3
[17:31:57] ~^
[17:31:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:31:57,319 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:31:57] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:31:57] SMILES Parse Error: check for mistakes around position 2:
[17:31:57] NATURAL:8047-24-3
[17:31:57] ~^
[17:31:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:31:57] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:57] SMILES Parse Error: check for mistakes around position 2:
[17:31:57] NATURAL:8006-87-9
[17:31:57] ~^
[17:31:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:57,356 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:31:57] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:31:57] SMILES Parse Error: check for mistakes around position 2:
[17:31:57] NATURAL:8006-87-9
[17:31:57] ~^
[17:31:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:31:57,673 INFO pino.train: Batch 80 | total=4.6716 | obj=0.2141 | season=1.4417 | wear=0.9279 | alignment=0.0247
[17:31:57] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:31:57] SMILES Parse Error: check for mistakes around position 2:
[17:31:57] NATURAL:89997-75-1
[17:31:57] ~^
[17:31:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:31:57,697 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:31:57] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:31:57] SMILES Parse Error: check for mistakes around position 2:
[17:31:57] NATURAL:89997-75-1
[17:31:57] ~^
[17:31:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:31:57] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:57] SMILES Parse Error: check for mistakes around position 2:
[17:31:57] NATURAL:8032-35-1
[17:31:57] ~^
[17:31:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:31:57,755 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:31:57] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:31:57] SMILES Parse Error: check for mistakes around position 2:
[17:31:57] NATURAL:8032-35-1
[17:31:57] ~^
[17:31:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:31:57] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:57] SMILES Parse Error: check for mistakes around position 2:
[17:31:57] NATURAL:8006-80-2
[17:31:57] ~^
[17:31:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:57,802 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:31:57] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:31:57] SMILES Parse Error: check for mistakes around position 2:
[17:31:57] NATURAL:8006-80-2
[17:31:57] ~^
[17:31:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:31:58,286 INFO pino.train: Batch 81 | total=4.5243 | obj=0.2119 | season=1.4723 | wear=0.8140 | alignment=0.0250
[17:31:58] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:31:58] SMILES Parse Error: check for mistakes around position 2:
[17:31:58] NATURAL:8013-76-1
[17:31:58] ~^
[17:31:58] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:31:58,336 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:31:58] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:31:58] SMILES Parse Error: check for mistakes around position 2:
[17:31:58] NATURAL:8013-76-1
[17:31:58] ~^
[17:31:58] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:31:58,784 INFO pino.train: Batch 82 | total=4.4947 | obj=0.2086 | season=1.4951 | wear=0.7690 | alignment=0.0303
[17:31:58] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:58] SMILES Parse Error: check for mistakes around position 2:
[17:31:58] NATURAL:8002-73-1
[17:31:58] ~^
[17:31:58] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:58,818 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:31:58] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:31:58] SMILES Parse Error: check for mistakes around position 2:
[17:31:58] NATURAL:8002-73-1
[17:31:58] ~^
[17:31:58] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:31:59,276 INFO pino.train: Batch 83 | total=4.3481 | obj=0.2061 | season=1.4609 | wear=0.7224 | alignment=0.0248
[17:31:59] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:59] SMILES Parse Error: check for mistakes around position 2:
[17:31:59] NATURAL:8008-56-8
[17:31:59] ~^
[17:31:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:59,300 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:31:59] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:31:59] SMILES Parse Error: check for mistakes around position 2:
[17:31:59] NATURAL:8008-56-8
[17:31:59] ~^
[17:31:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:31:59,599 INFO pino.train: Batch 84 | total=4.5042 | obj=0.2081 | season=1.4609 | wear=0.8055 | alignment=0.0274
2026-07-07 17:32:00,074 INFO pino.train: Batch 85 | total=4.2462 | obj=0.2046 | season=1.4009 | wear=0.7302 | alignment=0.0243
2026-07-07 17:32:00,431 INFO pino.train: Batch 86 | total=4.4021 | obj=0.2083 | season=1.4849 | wear=0.7146 | alignment=0.0238
[17:32:00] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:00] SMILES Parse Error: check for mistakes around position 2:
[17:32:00] NATURAL:68916-26-7
[17:32:00] ~^
[17:32:00] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:00,471 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:32:00] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:00] SMILES Parse Error: check for mistakes around position 2:
[17:32:00] NATURAL:68916-26-7
[17:32:00] ~^
[17:32:00] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:32:00] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:00] SMILES Parse Error: check for mistakes around position 2:
[17:32:00] NATURAL:8008-56-8
[17:32:00] ~^
[17:32:00] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:00,522 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:32:00] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:00] SMILES Parse Error: check for mistakes around position 2:
[17:32:00] NATURAL:8008-56-8
[17:32:00] ~^
[17:32:00] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:00,772 INFO pino.train: Batch 87 | total=4.3982 | obj=0.2040 | season=1.4334 | wear=0.7694 | alignment=0.0252
[17:32:00] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:00] SMILES Parse Error: check for mistakes around position 2:
[17:32:00] NATURAL:8032-35-1
[17:32:00] ~^
[17:32:00] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:00,822 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:00] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:00] SMILES Parse Error: check for mistakes around position 2:
[17:32:00] NATURAL:8032-35-1
[17:32:00] ~^
[17:32:00] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:01,080 INFO pino.train: Batch 88 | total=4.4317 | obj=0.2102 | season=1.4690 | wear=0.7440 | alignment=0.0243
[17:32:01] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:01] SMILES Parse Error: check for mistakes around position 2:
[17:32:01] NATURAL:8013-76-1
[17:32:01] ~^
[17:32:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:01,094 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:01] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:01] SMILES Parse Error: check for mistakes around position 2:
[17:32:01] NATURAL:8013-76-1
[17:32:01] ~^
[17:32:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
[17:32:01] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:01] SMILES Parse Error: check for mistakes around position 2:
[17:32:01] NATURAL:8002-73-1
[17:32:01] ~^
[17:32:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:01,123 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:01] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:01] SMILES Parse Error: check for mistakes around position 2:
[17:32:01] NATURAL:8002-73-1
[17:32:01] ~^
[17:32:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:01] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:01] SMILES Parse Error: check for mistakes around position 2:
[17:32:01] NATURAL:8013-90-9
[17:32:01] ~^
[17:32:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:01,185 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:01] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:01] SMILES Parse Error: check for mistakes around position 2:
[17:32:01] NATURAL:8013-90-9
[17:32:01] ~^
[17:32:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:32:01] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:01] SMILES Parse Error: check for mistakes around position 2:
[17:32:01] NATURAL:8006-80-2
[17:32:01] ~^
[17:32:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:01,215 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:01] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:01] SMILES Parse Error: check for mistakes around position 2:
[17:32:01] NATURAL:8006-80-2
[17:32:01] ~^
[17:32:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:01,465 INFO pino.train: Batch 89 | total=4.4808 | obj=0.2057 | season=1.4893 | wear=0.7439 | alignment=0.0250
2026-07-07 17:32:01,684 INFO pino.train: Batch 90 | total=4.5643 | obj=0.2003 | season=1.3718 | wear=0.9297 | alignment=0.0245
[17:32:01] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:01] SMILES Parse Error: check for mistakes around position 2:
[17:32:01] NATURAL:85940-31-4
[17:32:01] ~^
[17:32:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:01,701 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:01] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:01] SMILES Parse Error: check for mistakes around position 2:
[17:32:01] NATURAL:85940-31-4
[17:32:01] ~^
[17:32:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:02,047 INFO pino.train: Batch 91 | total=4.4662 | obj=0.2010 | season=1.4406 | wear=0.7992 | alignment=0.0232
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8006-80-2
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:02,098 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8006-80-2
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8008-31-9
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:02,134 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8008-31-9
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8002-73-1
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:02,179 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8002-73-1
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:02,475 INFO pino.train: Batch 92 | total=4.2837 | obj=0.2157 | season=1.3987 | wear=0.7462 | alignment=0.0246
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8008-45-5
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:02,494 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8008-45-5
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8013-76-1
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:02,541 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8013-76-1
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:02,776 INFO pino.train: Batch 93 | total=4.6865 | obj=0.2071 | season=1.5098 | wear=0.8393 | alignment=0.0244
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8015-77-8
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:02,813 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:8015-77-8
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:68916-26-7
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:02,836 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:32:02] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:02] SMILES Parse Error: check for mistakes around position 2:
[17:32:02] NATURAL:68916-26-7
[17:32:02] ~^
[17:32:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:03,091 INFO pino.train: Batch 94 | total=4.2213 | obj=0.2017 | season=1.3876 | wear=0.7229 | alignment=0.0236
2026-07-07 17:32:03,398 INFO pino.train: Batch 95 | total=4.2914 | obj=0.2036 | season=1.3475 | wear=0.8083 | alignment=0.0248
[17:32:03] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:03] SMILES Parse Error: check for mistakes around position 2:
[17:32:03] NATURAL:8002-73-1
[17:32:03] ~^
[17:32:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:03,419 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:03] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:03] SMILES Parse Error: check for mistakes around position 2:
[17:32:03] NATURAL:8002-73-1
[17:32:03] ~^
[17:32:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:03,688 INFO pino.train: Batch 96 | total=3.8990 | obj=0.2082 | season=1.2567 | wear=0.6985 | alignment=0.0244
[17:32:03] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:03] SMILES Parse Error: check for mistakes around position 2:
[17:32:03] NATURAL:8047-24-3
[17:32:03] ~^
[17:32:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:03,743 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:03] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:03] SMILES Parse Error: check for mistakes around position 2:
[17:32:03] NATURAL:8047-24-3
[17:32:03] ~^
[17:32:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:32:03] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:03] SMILES Parse Error: check for mistakes around position 2:
[17:32:03] NATURAL:8013-76-1
[17:32:03] ~^
[17:32:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:03,770 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:03] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:03] SMILES Parse Error: check for mistakes around position 2:
[17:32:03] NATURAL:8013-76-1
[17:32:03] ~^
[17:32:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:04,036 INFO pino.train: Batch 97 | total=3.7288 | obj=0.2023 | season=1.1870 | wear=0.6859 | alignment=0.0255
2026-07-07 17:32:04,305 INFO pino.train: Batch 98 | total=4.6237 | obj=0.2042 | season=1.4937 | wear=0.8261 | alignment=0.0246
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:85940-31-4
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:04,329 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:85940-31-4
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:04,490 INFO pino.train: Batch 99 | total=4.3663 | obj=0.2070 | season=1.4523 | wear=0.7297 | alignment=0.0237
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:8013-90-9
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:04,524 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:8013-90-9
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:8008-45-5
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:04,561 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:8008-45-5
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:04,880 INFO pino.train: Batch 100 | total=4.4177 | obj=0.2048 | season=1.4411 | wear=0.7687 | alignment=0.0236
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:8006-80-2
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:04,911 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:8006-80-2
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:7462-86-6
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:04,929 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:7462-86-6
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:8032-35-1
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:04,959 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:8032-35-1
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:68916-26-7
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:04,982 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:32:04] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:04] SMILES Parse Error: check for mistakes around position 2:
[17:32:04] NATURAL:68916-26-7
[17:32:04] ~^
[17:32:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:05,238 INFO pino.train: Batch 101 | total=4.6296 | obj=0.2030 | season=1.4864 | wear=0.8326 | alignment=0.0230
2026-07-07 17:32:05,540 INFO pino.train: Batch 102 | total=4.1076 | obj=0.2031 | season=1.3338 | wear=0.7214 | alignment=0.0246
[17:32:05] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:05] SMILES Parse Error: check for mistakes around position 2:
[17:32:05] NATURAL:7462-86-6
[17:32:05] ~^
[17:32:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:05,556 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:05] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:05] SMILES Parse Error: check for mistakes around position 2:
[17:32:05] NATURAL:7462-86-6
[17:32:05] ~^
[17:32:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:32:05] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:05] SMILES Parse Error: check for mistakes around position 2:
[17:32:05] NATURAL:85940-31-4
[17:32:05] ~^
[17:32:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:05,568 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:05] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:05] SMILES Parse Error: check for mistakes around position 2:
[17:32:05] NATURAL:85940-31-4
[17:32:05] ~^
[17:32:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:05,772 INFO pino.train: Batch 103 | total=3.6412 | obj=0.2065 | season=1.1178 | wear=0.7149 | alignment=0.0244
2026-07-07 17:32:06,073 INFO pino.train: Batch 104 | total=3.7351 | obj=0.2092 | season=1.1467 | wear=0.7364 | alignment=0.0239
[17:32:06] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:06] SMILES Parse Error: check for mistakes around position 2:
[17:32:06] NATURAL:85409-36-9
[17:32:06] ~^
[17:32:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:06,094 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:06] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:06] SMILES Parse Error: check for mistakes around position 2:
[17:32:06] NATURAL:85409-36-9
[17:32:06] ~^
[17:32:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:32:06] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:06] SMILES Parse Error: check for mistakes around position 2:
[17:32:06] NATURAL:8008-31-9
[17:32:06] ~^
[17:32:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:06,130 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:32:06] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:06] SMILES Parse Error: check for mistakes around position 2:
[17:32:06] NATURAL:8008-31-9
[17:32:06] ~^
[17:32:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:06,382 INFO pino.train: Batch 105 | total=3.8398 | obj=0.2060 | season=1.2229 | wear=0.7098 | alignment=0.0220
[17:32:06] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:06] SMILES Parse Error: check for mistakes around position 2:
[17:32:06] NATURAL:8015-77-8
[17:32:06] ~^
[17:32:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:06,431 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:32:06] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:06] SMILES Parse Error: check for mistakes around position 2:
[17:32:06] NATURAL:8015-77-8
[17:32:06] ~^
[17:32:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:06,589 INFO pino.train: Batch 106 | total=3.3402 | obj=0.2031 | season=0.9942 | wear=0.6961 | alignment=0.0230
2026-07-07 17:32:06,911 INFO pino.train: Batch 107 | total=4.1087 | obj=0.2051 | season=1.1591 | wear=0.9288 | alignment=0.0244
2026-07-07 17:32:07,115 INFO pino.train: Batch 108 | total=4.5778 | obj=0.2018 | season=1.5420 | wear=0.7681 | alignment=0.0222
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:8008-45-5
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:07,135 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:8008-45-5
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:8008-57-9
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:07,171 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:8008-57-9
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:07,464 INFO pino.train: Batch 109 | total=3.6594 | obj=0.1995 | season=1.1500 | wear=0.7016 | alignment=0.0219
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:85409-36-9
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:07,525 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:85409-36-9
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:07,808 INFO pino.train: Batch 110 | total=5.5431 | obj=0.2023 | season=1.8264 | wear=0.9675 | alignment=0.0223
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:8002-73-1
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:07,830 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:8002-73-1
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:8047-24-3
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:07,880 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:8047-24-3
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:85409-36-9
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:07,919 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:85409-36-9
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:8002-73-1
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:07,947 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:07] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:07] SMILES Parse Error: check for mistakes around position 2:
[17:32:07] NATURAL:8002-73-1
[17:32:07] ~^
[17:32:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:08,219 INFO pino.train: Batch 111 | total=4.0371 | obj=0.1997 | season=1.2536 | wear=0.7874 | alignment=0.0233
[17:32:08] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:08] SMILES Parse Error: check for mistakes around position 2:
[17:32:08] NATURAL:8013-76-1
[17:32:08] ~^
[17:32:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:08,291 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:08] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:08] SMILES Parse Error: check for mistakes around position 2:
[17:32:08] NATURAL:8013-76-1
[17:32:08] ~^
[17:32:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:08,554 INFO pino.train: Batch 112 | total=3.5682 | obj=0.1981 | season=0.9795 | wear=0.8340 | alignment=0.0237
2026-07-07 17:32:08,883 INFO pino.train: Batch 113 | total=3.9138 | obj=0.2088 | season=1.1672 | wear=0.8228 | alignment=0.0206
[17:32:08] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:08] SMILES Parse Error: check for mistakes around position 2:
[17:32:08] NATURAL:8008-45-5
[17:32:08] ~^
[17:32:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:08,954 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:08] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:08] SMILES Parse Error: check for mistakes around position 2:
[17:32:08] NATURAL:8008-45-5
[17:32:08] ~^
[17:32:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:32:08] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:08] SMILES Parse Error: check for mistakes around position 2:
[17:32:08] NATURAL:8008-31-9
[17:32:08] ~^
[17:32:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:09,002 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:32:09] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:09] SMILES Parse Error: check for mistakes around position 2:
[17:32:09] NATURAL:8008-31-9
[17:32:09] ~^
[17:32:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:09,254 INFO pino.train: Batch 114 | total=4.0746 | obj=0.2014 | season=1.3132 | wear=0.7566 | alignment=0.0235
[17:32:09] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:09] SMILES Parse Error: check for mistakes around position 2:
[17:32:09] NATURAL:8006-87-9
[17:32:09] ~^
[17:32:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:09,340 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:09] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:09] SMILES Parse Error: check for mistakes around position 2:
[17:32:09] NATURAL:8006-87-9
[17:32:09] ~^
[17:32:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:32:09] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:09] SMILES Parse Error: check for mistakes around position 2:
[17:32:09] NATURAL:8008-45-5
[17:32:09] ~^
[17:32:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:09,399 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:09] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:09] SMILES Parse Error: check for mistakes around position 2:
[17:32:09] NATURAL:8008-45-5
[17:32:09] ~^
[17:32:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:09,908 INFO pino.train: Batch 115 | total=3.1899 | obj=0.1974 | season=0.8881 | wear=0.7356 | alignment=0.0218
[17:32:09] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:09] SMILES Parse Error: check for mistakes around position 2:
[17:32:09] NATURAL:8002-73-1
[17:32:09] ~^
[17:32:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:09,940 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:09] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:09] SMILES Parse Error: check for mistakes around position 2:
[17:32:09] NATURAL:8002-73-1
[17:32:09] ~^
[17:32:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:10,198 INFO pino.train: Batch 116 | total=3.7993 | obj=0.2062 | season=1.1711 | wear=0.7656 | alignment=0.0210
2026-07-07 17:32:10,552 INFO pino.train: Batch 117 | total=4.3248 | obj=0.2028 | season=1.3957 | wear=0.8072 | alignment=0.0200
[17:32:10] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:10] SMILES Parse Error: check for mistakes around position 2:
[17:32:10] NATURAL:8008-57-9
[17:32:10] ~^
[17:32:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:10,568 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:32:10] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:10] SMILES Parse Error: check for mistakes around position 2:
[17:32:10] NATURAL:8008-57-9
[17:32:10] ~^
[17:32:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:32:10] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:10] SMILES Parse Error: check for mistakes around position 2:
[17:32:10] NATURAL:8015-77-8
[17:32:10] ~^
[17:32:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:10,650 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:32:10] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:10] SMILES Parse Error: check for mistakes around position 2:
[17:32:10] NATURAL:8015-77-8
[17:32:10] ~^
[17:32:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:10,911 INFO pino.train: Batch 118 | total=4.4149 | obj=0.2028 | season=1.3663 | wear=0.8822 | alignment=0.0209
[17:32:10] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:10] SMILES Parse Error: check for mistakes around position 2:
[17:32:10] NATURAL:8008-57-9
[17:32:10] ~^
[17:32:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:10,925 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:32:10] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:10] SMILES Parse Error: check for mistakes around position 2:
[17:32:10] NATURAL:8008-57-9
[17:32:10] ~^
[17:32:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:32:10] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:10] SMILES Parse Error: check for mistakes around position 2:
[17:32:10] NATURAL:85940-31-4
[17:32:10] ~^
[17:32:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:10,951 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:10] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:10] SMILES Parse Error: check for mistakes around position 2:
[17:32:10] NATURAL:85940-31-4
[17:32:10] ~^
[17:32:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:10] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:10] SMILES Parse Error: check for mistakes around position 2:
[17:32:10] NATURAL:8013-90-9
[17:32:10] ~^
[17:32:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:10,978 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:10] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:10] SMILES Parse Error: check for mistakes around position 2:
[17:32:10] NATURAL:8013-90-9
[17:32:10] ~^
[17:32:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8002-73-1
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:11,034 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8002-73-1
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:11,300 INFO pino.train: Batch 119 | total=3.5129 | obj=0.2030 | season=0.9494 | wear=0.8389 | alignment=0.0199
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8015-61-0
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:32:11,322 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8015-61-0
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8047-24-3
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:11,402 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8047-24-3
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:11,670 INFO pino.train: Batch 120 | total=4.1485 | obj=0.2018 | season=1.3580 | wear=0.7607 | alignment=0.0222
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:7462-86-6
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:11,687 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:7462-86-6
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8015-61-0
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:32:11,734 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8015-61-0
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8008-56-8
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:11,766 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8008-56-8
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8006-80-2
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:11,791 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:11] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:11] SMILES Parse Error: check for mistakes around position 2:
[17:32:11] NATURAL:8006-80-2
[17:32:11] ~^
[17:32:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:12,069 INFO pino.train: Batch 121 | total=4.2576 | obj=0.1991 | season=1.4002 | wear=0.7692 | alignment=0.0165
[17:32:12] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:12] SMILES Parse Error: check for mistakes around position 2:
[17:32:12] NATURAL:8006-87-9
[17:32:12] ~^
[17:32:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:12,131 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:12] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:12] SMILES Parse Error: check for mistakes around position 2:
[17:32:12] NATURAL:8006-87-9
[17:32:12] ~^
[17:32:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:12,374 INFO pino.train: Batch 122 | total=3.7205 | obj=0.1997 | season=1.1257 | wear=0.7695 | alignment=0.0198
[17:32:12] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:12] SMILES Parse Error: check for mistakes around position 2:
[17:32:12] NATURAL:8008-56-8
[17:32:12] ~^
[17:32:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:12,418 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:32:12] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:12] SMILES Parse Error: check for mistakes around position 2:
[17:32:12] NATURAL:8008-56-8
[17:32:12] ~^
[17:32:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:32:12] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:12] SMILES Parse Error: check for mistakes around position 2:
[17:32:12] NATURAL:8006-87-9
[17:32:12] ~^
[17:32:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:12,445 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:12] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:12] SMILES Parse Error: check for mistakes around position 2:
[17:32:12] NATURAL:8006-87-9
[17:32:12] ~^
[17:32:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:12,766 INFO pino.train: Batch 123 | total=5.1674 | obj=0.2059 | season=1.8078 | wear=0.8099 | alignment=0.0198
[17:32:12] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:12] SMILES Parse Error: check for mistakes around position 2:
[17:32:12] NATURAL:8002-73-1
[17:32:12] ~^
[17:32:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:12,797 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:12] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:12] SMILES Parse Error: check for mistakes around position 2:
[17:32:12] NATURAL:8002-73-1
[17:32:12] ~^
[17:32:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:12] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:12] SMILES Parse Error: check for mistakes around position 2:
[17:32:12] NATURAL:8013-90-9
[17:32:12] ~^
[17:32:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:12,836 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:12] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:12] SMILES Parse Error: check for mistakes around position 2:
[17:32:12] NATURAL:8013-90-9
[17:32:12] ~^
[17:32:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:13,070 INFO pino.train: Batch 124 | total=4.0180 | obj=0.2043 | season=1.3424 | wear=0.6882 | alignment=0.0186
2026-07-07 17:32:13,281 INFO pino.train: Batch 125 | total=5.4984 | obj=0.2017 | season=1.9887 | wear=0.7502 | alignment=0.0168
2026-07-07 17:32:13,529 INFO pino.train: Batch 126 | total=4.1162 | obj=0.2049 | season=1.2834 | wear=0.7860 | alignment=0.0136
[17:32:13] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:13] SMILES Parse Error: check for mistakes around position 2:
[17:32:13] NATURAL:68916-26-7
[17:32:13] ~^
[17:32:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:13,559 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:32:13] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:13] SMILES Parse Error: check for mistakes around position 2:
[17:32:13] NATURAL:68916-26-7
[17:32:13] ~^
[17:32:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:32:13] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:13] SMILES Parse Error: check for mistakes around position 2:
[17:32:13] NATURAL:8008-45-5
[17:32:13] ~^
[17:32:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:13,594 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:13] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:13] SMILES Parse Error: check for mistakes around position 2:
[17:32:13] NATURAL:8008-45-5
[17:32:13] ~^
[17:32:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:13,895 INFO pino.train: Batch 127 | total=4.4381 | obj=0.2004 | season=1.4444 | wear=0.7790 | alignment=0.0108
[17:32:13] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:13] SMILES Parse Error: check for mistakes around position 2:
[17:32:13] NATURAL:8013-90-9
[17:32:13] ~^
[17:32:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:13,914 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:13] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:13] SMILES Parse Error: check for mistakes around position 2:
[17:32:13] NATURAL:8013-90-9
[17:32:13] ~^
[17:32:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:32:13] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:13] SMILES Parse Error: check for mistakes around position 2:
[17:32:13] NATURAL:8006-80-2
[17:32:13] ~^
[17:32:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:13,972 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:13] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:13] SMILES Parse Error: check for mistakes around position 2:
[17:32:13] NATURAL:8006-80-2
[17:32:13] ~^
[17:32:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:32:13] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:13] SMILES Parse Error: check for mistakes around position 2:
[17:32:13] NATURAL:85940-31-4
[17:32:13] ~^
[17:32:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:14,001 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:14] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:14] SMILES Parse Error: check for mistakes around position 2:
[17:32:14] NATURAL:85940-31-4
[17:32:14] ~^
[17:32:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:14,290 INFO pino.train: Batch 128 | total=4.9852 | obj=0.2064 | season=1.5227 | wear=0.9855 | alignment=0.0080
[17:32:14] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:32:14] SMILES Parse Error: check for mistakes around position 2:
[17:32:14] NATURAL:8015-61-0
[17:32:14] ~^
[17:32:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:32:14,313 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:32:14] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:32:14] SMILES Parse Error: check for mistakes around position 2:
[17:32:14] NATURAL:8015-61-0
[17:32:14] ~^
[17:32:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:32:14,643 INFO pino.train: Batch 129 | total=3.4439 | obj=0.2023 | season=0.8291 | wear=0.9152 | alignment=0.0071
[17:32:14] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:14] SMILES Parse Error: check for mistakes around position 2:
[17:32:14] NATURAL:68916-26-7
[17:32:14] ~^
[17:32:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:14,701 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:32:14] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:14] SMILES Parse Error: check for mistakes around position 2:
[17:32:14] NATURAL:68916-26-7
[17:32:14] ~^
[17:32:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:14,962 INFO pino.train: Batch 130 | total=3.9833 | obj=0.2055 | season=1.2800 | wear=0.7316 | alignment=0.0071
[17:32:14] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:14] SMILES Parse Error: check for mistakes around position 2:
[17:32:14] NATURAL:85940-31-4
[17:32:14] ~^
[17:32:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:14,990 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:14] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:14] SMILES Parse Error: check for mistakes around position 2:
[17:32:14] NATURAL:85940-31-4
[17:32:14] ~^
[17:32:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:15,305 INFO pino.train: Batch 131 | total=5.3218 | obj=0.2051 | season=1.8482 | wear=0.8155 | alignment=0.0018
[17:32:15] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:15] SMILES Parse Error: check for mistakes around position 2:
[17:32:15] NATURAL:8008-45-5
[17:32:15] ~^
[17:32:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:15,327 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:15] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:15] SMILES Parse Error: check for mistakes around position 2:
[17:32:15] NATURAL:8008-45-5
[17:32:15] ~^
[17:32:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:32:15] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:15] SMILES Parse Error: check for mistakes around position 2:
[17:32:15] NATURAL:8032-35-1
[17:32:15] ~^
[17:32:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:15,366 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:15] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:15] SMILES Parse Error: check for mistakes around position 2:
[17:32:15] NATURAL:8032-35-1
[17:32:15] ~^
[17:32:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:32:15] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:15] SMILES Parse Error: check for mistakes around position 2:
[17:32:15] NATURAL:8002-73-1
[17:32:15] ~^
[17:32:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:15,401 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:15] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:15] SMILES Parse Error: check for mistakes around position 2:
[17:32:15] NATURAL:8002-73-1
[17:32:15] ~^
[17:32:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:15,688 INFO pino.train: Batch 132 | total=4.2608 | obj=0.2058 | season=1.4031 | wear=0.7286 | alignment=0.0063
[17:32:15] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:15] SMILES Parse Error: check for mistakes around position 2:
[17:32:15] NATURAL:8015-77-8
[17:32:15] ~^
[17:32:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:15,745 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:32:15] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:15] SMILES Parse Error: check for mistakes around position 2:
[17:32:15] NATURAL:8015-77-8
[17:32:15] ~^
[17:32:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:15,936 INFO pino.train: Batch 133 | total=3.9276 | obj=0.1995 | season=1.1934 | wear=0.7794 | alignment=0.0016
[17:32:15] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:15] SMILES Parse Error: check for mistakes around position 2:
[17:32:15] NATURAL:8002-73-1
[17:32:15] ~^
[17:32:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:15,989 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:15] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:15] SMILES Parse Error: check for mistakes around position 2:
[17:32:15] NATURAL:8002-73-1
[17:32:15] ~^
[17:32:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8006-87-9
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:16,020 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8006-87-9
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:16,267 INFO pino.train: Batch 134 | total=4.4317 | obj=0.1969 | season=1.3133 | wear=0.9172 | alignment=0.0049
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8002-73-1
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:16,309 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8002-73-1
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:85940-31-4
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:16,338 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:85940-31-4
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:16,509 INFO pino.train: Batch 135 | total=4.6253 | obj=0.1961 | season=1.5083 | wear=0.8106 | alignment=0.0077
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8002-73-1
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:16,544 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8002-73-1
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:16,826 INFO pino.train: Batch 136 | total=3.8296 | obj=0.2038 | season=1.1636 | wear=0.7618 | alignment=0.0079
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8008-45-5
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:16,862 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8008-45-5
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:85940-31-4
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:16,885 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:85940-31-4
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8002-73-1
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:16,915 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8002-73-1
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8006-80-2
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:16,957 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:16] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:16] SMILES Parse Error: check for mistakes around position 2:
[17:32:16] NATURAL:8006-80-2
[17:32:16] ~^
[17:32:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:17,254 INFO pino.train: Batch 137 | total=3.7741 | obj=0.2066 | season=1.1953 | wear=0.7001 | alignment=0.0095
[17:32:17] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:17] SMILES Parse Error: check for mistakes around position 2:
[17:32:17] NATURAL:85940-31-4
[17:32:17] ~^
[17:32:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:17,288 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:17] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:17] SMILES Parse Error: check for mistakes around position 2:
[17:32:17] NATURAL:85940-31-4
[17:32:17] ~^
[17:32:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:17] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:17] SMILES Parse Error: check for mistakes around position 2:
[17:32:17] NATURAL:8015-77-8
[17:32:17] ~^
[17:32:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:17,313 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:32:17] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:17] SMILES Parse Error: check for mistakes around position 2:
[17:32:17] NATURAL:8015-77-8
[17:32:17] ~^
[17:32:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:17,559 INFO pino.train: Batch 138 | total=3.9782 | obj=0.2026 | season=1.2090 | wear=0.7919 | alignment=0.0016
[17:32:17] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:17] SMILES Parse Error: check for mistakes around position 2:
[17:32:17] NATURAL:8015-77-8
[17:32:17] ~^
[17:32:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:17,579 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:32:17] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:17] SMILES Parse Error: check for mistakes around position 2:
[17:32:17] NATURAL:8015-77-8
[17:32:17] ~^
[17:32:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
[17:32:17] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:17] SMILES Parse Error: check for mistakes around position 2:
[17:32:17] NATURAL:8002-73-1
[17:32:17] ~^
[17:32:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:17,650 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:17] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:17] SMILES Parse Error: check for mistakes around position 2:
[17:32:17] NATURAL:8002-73-1
[17:32:17] ~^
[17:32:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:17,950 INFO pino.train: Batch 139 | total=3.5931 | obj=0.2092 | season=1.0869 | wear=0.7214 | alignment=0.0033
2026-07-07 17:32:18,245 INFO pino.train: Batch 140 | total=4.1752 | obj=0.2099 | season=1.3053 | wear=0.7956 | alignment=0.0090
[17:32:18] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:18] SMILES Parse Error: check for mistakes around position 2:
[17:32:18] NATURAL:89997-75-1
[17:32:18] ~^
[17:32:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:18,331 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:18] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:18] SMILES Parse Error: check for mistakes around position 2:
[17:32:18] NATURAL:89997-75-1
[17:32:18] ~^
[17:32:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:18,602 INFO pino.train: Batch 141 | total=4.7775 | obj=0.2061 | season=1.6525 | wear=0.7324 | alignment=0.0022
[17:32:18] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:18] SMILES Parse Error: check for mistakes around position 2:
[17:32:18] NATURAL:7462-86-6
[17:32:18] ~^
[17:32:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:18,635 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:18] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:18] SMILES Parse Error: check for mistakes around position 2:
[17:32:18] NATURAL:7462-86-6
[17:32:18] ~^
[17:32:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:32:18] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:18] SMILES Parse Error: check for mistakes around position 2:
[17:32:18] NATURAL:8006-80-2
[17:32:18] ~^
[17:32:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:18,658 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:18] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:18] SMILES Parse Error: check for mistakes around position 2:
[17:32:18] NATURAL:8006-80-2
[17:32:18] ~^
[17:32:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:18,955 INFO pino.train: Batch 142 | total=4.9217 | obj=0.2066 | season=1.7024 | wear=0.7380 | alignment=0.0071
[17:32:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:19] SMILES Parse Error: check for mistakes around position 2:
[17:32:19] NATURAL:8002-73-1
[17:32:19] ~^
[17:32:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:19,030 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:19] SMILES Parse Error: check for mistakes around position 2:
[17:32:19] NATURAL:8002-73-1
[17:32:19] ~^
[17:32:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:19,309 INFO pino.train: Batch 143 | total=4.4899 | obj=0.2068 | season=1.4608 | wear=0.7702 | alignment=0.0058
[17:32:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:19] SMILES Parse Error: check for mistakes around position 2:
[17:32:19] NATURAL:8002-73-1
[17:32:19] ~^
[17:32:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:19,363 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:19] SMILES Parse Error: check for mistakes around position 2:
[17:32:19] NATURAL:8002-73-1
[17:32:19] ~^
[17:32:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:19] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:19] SMILES Parse Error: check for mistakes around position 2:
[17:32:19] NATURAL:85940-31-4
[17:32:19] ~^
[17:32:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:19,395 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:19] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:19] SMILES Parse Error: check for mistakes around position 2:
[17:32:19] NATURAL:85940-31-4
[17:32:19] ~^
[17:32:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:19] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:19] SMILES Parse Error: check for mistakes around position 2:
[17:32:19] NATURAL:8047-24-3
[17:32:19] ~^
[17:32:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:19,416 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:19] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:19] SMILES Parse Error: check for mistakes around position 2:
[17:32:19] NATURAL:8047-24-3
[17:32:19] ~^
[17:32:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:19,675 INFO pino.train: Batch 144 | total=4.0539 | obj=0.2115 | season=1.2147 | wear=0.8124 | alignment=0.0040
[17:32:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:19] SMILES Parse Error: check for mistakes around position 2:
[17:32:19] NATURAL:8002-73-1
[17:32:19] ~^
[17:32:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:19,740 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:19] SMILES Parse Error: check for mistakes around position 2:
[17:32:19] NATURAL:8002-73-1
[17:32:19] ~^
[17:32:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:20,001 INFO pino.train: Batch 145 | total=4.9262 | obj=0.1999 | season=1.5946 | wear=0.8576 | alignment=0.0099
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8006-80-2
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:20,036 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8006-80-2
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8013-76-1
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:20,102 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8013-76-1
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8013-90-9
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:20,128 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8013-90-9
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8008-31-9
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:20,155 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8008-31-9
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:89997-75-1
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:20,183 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:89997-75-1
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:20,469 INFO pino.train: Batch 146 | total=4.9076 | obj=0.2024 | season=1.6275 | wear=0.8054 | alignment=0.0061
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8002-73-1
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:20,511 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8002-73-1
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:20,749 INFO pino.train: Batch 147 | total=3.8961 | obj=0.2016 | season=1.1441 | wear=0.8052 | alignment=0.0042
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:85940-31-4
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:20,776 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:85940-31-4
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8006-81-3
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:20,808 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:20] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:20] SMILES Parse Error: check for mistakes around position 2:
[17:32:20] NATURAL:8006-81-3
[17:32:20] ~^
[17:32:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:21,111 INFO pino.train: Batch 148 | total=4.1688 | obj=0.2001 | season=1.2885 | wear=0.7937 | alignment=0.0025
[17:32:21] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:21] SMILES Parse Error: check for mistakes around position 2:
[17:32:21] NATURAL:8002-73-1
[17:32:21] ~^
[17:32:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:21,146 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:21] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:21] SMILES Parse Error: check for mistakes around position 2:
[17:32:21] NATURAL:8002-73-1
[17:32:21] ~^
[17:32:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:21,357 INFO pino.train: Batch 149 | total=4.0353 | obj=0.2033 | season=1.3426 | wear=0.6614 | alignment=0.0061
[17:32:21] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:21] SMILES Parse Error: check for mistakes around position 2:
[17:32:21] NATURAL:8002-73-1
[17:32:21] ~^
[17:32:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:21,400 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:21] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:21] SMILES Parse Error: check for mistakes around position 2:
[17:32:21] NATURAL:8002-73-1
[17:32:21] ~^
[17:32:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:21,721 INFO pino.train: Batch 150 | total=3.7555 | obj=0.2051 | season=1.1770 | wear=0.6954 | alignment=0.0105
[17:32:21] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:21] SMILES Parse Error: check for mistakes around position 2:
[17:32:21] NATURAL:8008-45-5
[17:32:21] ~^
[17:32:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:21,742 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:21] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:21] SMILES Parse Error: check for mistakes around position 2:
[17:32:21] NATURAL:8008-45-5
[17:32:21] ~^
[17:32:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:21,969 INFO pino.train: Batch 151 | total=3.7829 | obj=0.2023 | season=1.1949 | wear=0.6907 | alignment=0.0044
[17:32:21] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:21] SMILES Parse Error: check for mistakes around position 2:
[17:32:21] NATURAL:8002-73-1
[17:32:21] ~^
[17:32:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:21,990 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:21] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:21] SMILES Parse Error: check for mistakes around position 2:
[17:32:21] NATURAL:8002-73-1
[17:32:21] ~^
[17:32:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:22,187 INFO pino.train: Batch 152 | total=4.5286 | obj=0.1990 | season=1.5227 | wear=0.7197 | alignment=0.0082
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:85409-36-9
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:22,238 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:85409-36-9
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8013-90-9
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:22,277 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8013-90-9
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8006-87-9
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:22,299 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8006-87-9
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:22,559 INFO pino.train: Batch 153 | total=4.7192 | obj=0.2025 | season=1.5270 | wear=0.8132 | alignment=0.0039
2026-07-07 17:32:22,816 INFO pino.train: Batch 154 | total=4.1051 | obj=0.2020 | season=1.2597 | wear=0.7855 | alignment=0.0051
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8002-73-1
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:22,837 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8002-73-1
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8008-45-5
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:22,872 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8008-45-5
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:85940-31-4
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:22,901 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:85940-31-4
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8008-57-9
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:22,927 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8008-57-9
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8015-77-8
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:22,968 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8015-77-8
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
[17:32:22] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:22] SMILES Parse Error: check for mistakes around position 2:
[17:32:22] NATURAL:8013-76-1
[17:32:22] ~^
[17:32:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:22,996 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:23] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:23] SMILES Parse Error: check for mistakes around position 2:
[17:32:23] NATURAL:8013-76-1
[17:32:23] ~^
[17:32:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:23,272 INFO pino.train: Batch 155 | total=4.9279 | obj=0.2077 | season=1.6025 | wear=0.8405 | alignment=0.0019
[17:32:23] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:23] SMILES Parse Error: check for mistakes around position 2:
[17:32:23] NATURAL:8002-73-1
[17:32:23] ~^
[17:32:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:23,309 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:23] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:23] SMILES Parse Error: check for mistakes around position 2:
[17:32:23] NATURAL:8002-73-1
[17:32:23] ~^
[17:32:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:23] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:23] SMILES Parse Error: check for mistakes around position 2:
[17:32:23] NATURAL:85409-36-9
[17:32:23] ~^
[17:32:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:23,345 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:23] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:23] SMILES Parse Error: check for mistakes around position 2:
[17:32:23] NATURAL:85409-36-9
[17:32:23] ~^
[17:32:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:23,596 INFO pino.train: Batch 156 | total=4.1383 | obj=0.1990 | season=1.3383 | wear=0.7120 | alignment=0.0027
[17:32:23] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:23] SMILES Parse Error: check for mistakes around position 2:
[17:32:23] NATURAL:8006-87-9
[17:32:23] ~^
[17:32:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:23,632 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:23] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:23] SMILES Parse Error: check for mistakes around position 2:
[17:32:23] NATURAL:8006-87-9
[17:32:23] ~^
[17:32:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:23,894 INFO pino.train: Batch 157 | total=4.4206 | obj=0.2000 | season=1.4173 | wear=0.7732 | alignment=0.0029
[17:32:23] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:23] SMILES Parse Error: check for mistakes around position 2:
[17:32:23] NATURAL:85940-31-4
[17:32:23] ~^
[17:32:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:23,915 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:23] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:23] SMILES Parse Error: check for mistakes around position 2:
[17:32:23] NATURAL:85940-31-4
[17:32:23] ~^
[17:32:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:23] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:23] SMILES Parse Error: check for mistakes around position 2:
[17:32:23] NATURAL:7462-86-6
[17:32:23] ~^
[17:32:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:23,985 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:23] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:23] SMILES Parse Error: check for mistakes around position 2:
[17:32:23] NATURAL:7462-86-6
[17:32:23] ~^
[17:32:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:24,276 INFO pino.train: Batch 158 | total=4.3469 | obj=0.1970 | season=1.3770 | wear=0.7793 | alignment=0.0050
[17:32:24] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:24] SMILES Parse Error: check for mistakes around position 2:
[17:32:24] NATURAL:85940-31-4
[17:32:24] ~^
[17:32:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:24,298 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:24] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:24] SMILES Parse Error: check for mistakes around position 2:
[17:32:24] NATURAL:85940-31-4
[17:32:24] ~^
[17:32:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:24] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:24] SMILES Parse Error: check for mistakes around position 2:
[17:32:24] NATURAL:85409-36-9
[17:32:24] ~^
[17:32:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:24,332 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:24] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:24] SMILES Parse Error: check for mistakes around position 2:
[17:32:24] NATURAL:85409-36-9
[17:32:24] ~^
[17:32:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:32:24] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:24] SMILES Parse Error: check for mistakes around position 2:
[17:32:24] NATURAL:89997-75-1
[17:32:24] ~^
[17:32:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:24,364 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:24] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:24] SMILES Parse Error: check for mistakes around position 2:
[17:32:24] NATURAL:89997-75-1
[17:32:24] ~^
[17:32:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:32:24] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:24] SMILES Parse Error: check for mistakes around position 2:
[17:32:24] NATURAL:8013-76-1
[17:32:24] ~^
[17:32:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:24,387 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:24] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:24] SMILES Parse Error: check for mistakes around position 2:
[17:32:24] NATURAL:8013-76-1
[17:32:24] ~^
[17:32:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:24,644 INFO pino.train: Batch 159 | total=4.5578 | obj=0.2090 | season=1.4591 | wear=0.7991 | alignment=0.0020
[17:32:24] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:24] SMILES Parse Error: check for mistakes around position 2:
[17:32:24] NATURAL:8006-87-9
[17:32:24] ~^
[17:32:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:24,719 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:24] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:24] SMILES Parse Error: check for mistakes around position 2:
[17:32:24] NATURAL:8006-87-9
[17:32:24] ~^
[17:32:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:24,996 INFO pino.train: Batch 160 | total=4.8793 | obj=0.1963 | season=1.5931 | wear=0.8172 | alignment=0.0027
2026-07-07 17:32:25,321 INFO pino.train: Batch 161 | total=4.2630 | obj=0.1980 | season=1.3519 | wear=0.7591 | alignment=0.0046
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:8008-31-9
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:25,392 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:8008-31-9
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:7462-86-6
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:25,404 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:7462-86-6
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:8032-35-1
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:25,414 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:8032-35-1
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:25,703 INFO pino.train: Batch 162 | total=4.0221 | obj=0.2073 | season=1.2418 | wear=0.7558 | alignment=0.0025
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:8032-35-1
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:25,733 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:8032-35-1
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:8006-87-9
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:25,791 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:8006-87-9
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:8006-81-3
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:25,830 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:25] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:25] SMILES Parse Error: check for mistakes around position 2:
[17:32:25] NATURAL:8006-81-3
[17:32:25] ~^
[17:32:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:26,085 INFO pino.train: Batch 163 | total=4.1852 | obj=0.2031 | season=1.3675 | wear=0.7013 | alignment=0.0097
[17:32:26] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:26] SMILES Parse Error: check for mistakes around position 2:
[17:32:26] NATURAL:8006-87-9
[17:32:26] ~^
[17:32:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:26,102 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:26] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:26] SMILES Parse Error: check for mistakes around position 2:
[17:32:26] NATURAL:8006-87-9
[17:32:26] ~^
[17:32:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:26,416 INFO pino.train: Batch 164 | total=4.4071 | obj=0.2044 | season=1.3660 | wear=0.8235 | alignment=0.0043
[17:32:26] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:26] SMILES Parse Error: check for mistakes around position 2:
[17:32:26] NATURAL:89997-75-1
[17:32:26] ~^
[17:32:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:26,432 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:26] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:26] SMILES Parse Error: check for mistakes around position 2:
[17:32:26] NATURAL:89997-75-1
[17:32:26] ~^
[17:32:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:32:26] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:26] SMILES Parse Error: check for mistakes around position 2:
[17:32:26] NATURAL:85409-36-9
[17:32:26] ~^
[17:32:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:26,470 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:26] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:26] SMILES Parse Error: check for mistakes around position 2:
[17:32:26] NATURAL:85409-36-9
[17:32:26] ~^
[17:32:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:26,805 INFO pino.train: Batch 165 | total=4.4272 | obj=0.1943 | season=1.4121 | wear=0.7826 | alignment=0.0017
[17:32:26] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:26] SMILES Parse Error: check for mistakes around position 2:
[17:32:26] NATURAL:8013-90-9
[17:32:26] ~^
[17:32:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:26,851 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:26] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:26] SMILES Parse Error: check for mistakes around position 2:
[17:32:26] NATURAL:8013-90-9
[17:32:26] ~^
[17:32:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:27,142 INFO pino.train: Batch 166 | total=4.5217 | obj=0.2055 | season=1.4832 | wear=0.7505 | alignment=0.0060
2026-07-07 17:32:27,490 INFO pino.train: Batch 167 | total=4.2536 | obj=0.2017 | season=1.3841 | wear=0.7165 | alignment=0.0063
[17:32:27] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:27] SMILES Parse Error: check for mistakes around position 2:
[17:32:27] NATURAL:8002-73-1
[17:32:27] ~^
[17:32:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:27,510 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:27] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:27] SMILES Parse Error: check for mistakes around position 2:
[17:32:27] NATURAL:8002-73-1
[17:32:27] ~^
[17:32:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:27,784 INFO pino.train: Batch 168 | total=4.1344 | obj=0.2026 | season=1.3441 | wear=0.6956 | alignment=0.0022
2026-07-07 17:32:28,069 INFO pino.train: Batch 169 | total=4.5335 | obj=0.2007 | season=1.4940 | wear=0.7356 | alignment=0.0025
2026-07-07 17:32:28,407 INFO pino.train: Batch 170 | total=4.3754 | obj=0.1999 | season=1.3842 | wear=0.7764 | alignment=0.0016
[17:32:28] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:28] SMILES Parse Error: check for mistakes around position 2:
[17:32:28] NATURAL:68916-26-7
[17:32:28] ~^
[17:32:28] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:28,469 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:32:28] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:28] SMILES Parse Error: check for mistakes around position 2:
[17:32:28] NATURAL:68916-26-7
[17:32:28] ~^
[17:32:28] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:28,752 INFO pino.train: Batch 171 | total=4.5428 | obj=0.2036 | season=1.4011 | wear=0.8507 | alignment=0.0052
[17:32:28] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:28] SMILES Parse Error: check for mistakes around position 2:
[17:32:28] NATURAL:8008-31-9
[17:32:28] ~^
[17:32:28] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:28,768 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:32:28] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:28] SMILES Parse Error: check for mistakes around position 2:
[17:32:28] NATURAL:8008-31-9
[17:32:28] ~^
[17:32:28] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:32:28] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:28] SMILES Parse Error: check for mistakes around position 2:
[17:32:28] NATURAL:8032-35-1
[17:32:28] ~^
[17:32:28] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:28,791 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:28] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:28] SMILES Parse Error: check for mistakes around position 2:
[17:32:28] NATURAL:8032-35-1
[17:32:28] ~^
[17:32:28] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:32:28] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:28] SMILES Parse Error: check for mistakes around position 2:
[17:32:28] NATURAL:8047-24-3
[17:32:28] ~^
[17:32:28] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:28,880 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:28] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:28] SMILES Parse Error: check for mistakes around position 2:
[17:32:28] NATURAL:8047-24-3
[17:32:28] ~^
[17:32:28] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:29,133 INFO pino.train: Batch 172 | total=4.6126 | obj=0.2071 | season=1.4536 | wear=0.8304 | alignment=0.0041
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:8008-45-5
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:29,193 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:8008-45-5
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:29,493 INFO pino.train: Batch 173 | total=4.2563 | obj=0.2081 | season=1.3802 | wear=0.7208 | alignment=0.0026
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:7462-86-6
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:29,496 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:7462-86-6
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:8006-80-2
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:29,514 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:8006-80-2
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:8015-61-0
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:32:29,562 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:8015-61-0
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:8006-81-3
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:29,600 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:8006-81-3
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:29,803 INFO pino.train: Batch 174 | total=4.5044 | obj=0.1960 | season=1.4208 | wear=0.8093 | alignment=0.0066
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:8013-90-9
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:29,881 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:29] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:29] SMILES Parse Error: check for mistakes around position 2:
[17:32:29] NATURAL:8013-90-9
[17:32:29] ~^
[17:32:29] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:30,136 INFO pino.train: Batch 175 | total=4.5286 | obj=0.2028 | season=1.3759 | wear=0.8761 | alignment=0.0031
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:8006-80-2
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:30,162 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:8006-80-2
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:8008-45-5
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:30,185 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:8008-45-5
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:30,418 INFO pino.train: Batch 176 | total=4.2351 | obj=0.1996 | season=1.3868 | wear=0.7057 | alignment=0.0016
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:8002-73-1
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:30,439 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:8002-73-1
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:85409-36-9
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:30,484 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:85409-36-9
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:8008-31-9
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:30,507 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:8008-31-9
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:8008-56-8
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:30,529 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:32:30] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:30] SMILES Parse Error: check for mistakes around position 2:
[17:32:30] NATURAL:8008-56-8
[17:32:30] ~^
[17:32:30] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:30,755 INFO pino.train: Batch 177 | total=4.2420 | obj=0.2077 | season=1.3962 | wear=0.6949 | alignment=0.0012
2026-07-07 17:32:31,077 INFO pino.train: Batch 178 | total=4.2441 | obj=0.2014 | season=1.3816 | wear=0.7105 | alignment=0.0053
[17:32:31] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:31] SMILES Parse Error: check for mistakes around position 2:
[17:32:31] NATURAL:85940-31-4
[17:32:31] ~^
[17:32:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:31,096 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:31] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:31] SMILES Parse Error: check for mistakes around position 2:
[17:32:31] NATURAL:85940-31-4
[17:32:31] ~^
[17:32:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:31] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:31] SMILES Parse Error: check for mistakes around position 2:
[17:32:31] NATURAL:8006-80-2
[17:32:31] ~^
[17:32:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:31,172 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:31] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:31] SMILES Parse Error: check for mistakes around position 2:
[17:32:31] NATURAL:8006-80-2
[17:32:31] ~^
[17:32:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:31,421 INFO pino.train: Batch 179 | total=4.0691 | obj=0.2031 | season=1.3104 | wear=0.6964 | alignment=0.0030
[17:32:31] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:31] SMILES Parse Error: check for mistakes around position 2:
[17:32:31] NATURAL:8006-81-3
[17:32:31] ~^
[17:32:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:31,451 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:31] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:31] SMILES Parse Error: check for mistakes around position 2:
[17:32:31] NATURAL:8006-81-3
[17:32:31] ~^
[17:32:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
[17:32:31] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:31] SMILES Parse Error: check for mistakes around position 2:
[17:32:31] NATURAL:8002-73-1
[17:32:31] ~^
[17:32:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:31,485 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:31] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:31] SMILES Parse Error: check for mistakes around position 2:
[17:32:31] NATURAL:8002-73-1
[17:32:31] ~^
[17:32:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:31,763 INFO pino.train: Batch 180 | total=4.3442 | obj=0.2024 | season=1.3293 | wear=0.8262 | alignment=0.0047
[17:32:31] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:31] SMILES Parse Error: check for mistakes around position 2:
[17:32:31] NATURAL:8008-45-5
[17:32:31] ~^
[17:32:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:31,790 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:31] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:31] SMILES Parse Error: check for mistakes around position 2:
[17:32:31] NATURAL:8008-45-5
[17:32:31] ~^
[17:32:31] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:32,058 INFO pino.train: Batch 181 | total=4.0569 | obj=0.2061 | season=1.2588 | wear=0.7543 | alignment=0.0043
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:85940-31-4
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:32,082 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:85940-31-4
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:7462-86-6
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:32,108 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:7462-86-6
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8006-81-3
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:32,136 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8006-81-3
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:32,441 INFO pino.train: Batch 182 | total=4.1439 | obj=0.2039 | season=1.3073 | wear=0.7473 | alignment=0.0025
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8013-90-9
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:32,491 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8013-90-9
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8002-73-1
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:32,520 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8002-73-1
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8002-73-1
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:32,553 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8002-73-1
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:32,767 INFO pino.train: Batch 183 | total=4.2896 | obj=0.2033 | season=1.4461 | wear=0.6637 | alignment=0.0041
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8013-76-1
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:32,798 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8013-76-1
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8002-73-1
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:32,855 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:32] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:32] SMILES Parse Error: check for mistakes around position 2:
[17:32:32] NATURAL:8002-73-1
[17:32:32] ~^
[17:32:32] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:33,083 INFO pino.train: Batch 184 | total=4.3853 | obj=0.2007 | season=1.3787 | wear=0.7922 | alignment=0.0045
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:8006-81-3
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:33,102 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:8006-81-3
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:8002-73-1
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:33,138 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:8002-73-1
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:8008-56-8
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:33,174 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:8008-56-8
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:33,403 INFO pino.train: Batch 185 | total=4.0478 | obj=0.2074 | season=1.2617 | wear=0.7452 | alignment=0.0033
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:8002-73-1
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:33,443 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:8002-73-1
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:8047-24-3
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:33,475 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:8047-24-3
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:33,706 INFO pino.train: Batch 186 | total=3.7981 | obj=0.2110 | season=1.1511 | wear=0.7387 | alignment=0.0053
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:89997-75-1
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:33,779 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:33] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:33] SMILES Parse Error: check for mistakes around position 2:
[17:32:33] NATURAL:89997-75-1
[17:32:33] ~^
[17:32:33] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:34,094 INFO pino.train: Batch 187 | total=4.0530 | obj=0.1995 | season=1.2703 | wear=0.7440 | alignment=0.0060
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8032-35-1
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:34,111 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8032-35-1
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:34,454 INFO pino.train: Batch 188 | total=4.3920 | obj=0.2028 | season=1.3217 | wear=0.8697 | alignment=0.0028
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8002-73-1
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:34,471 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8002-73-1
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8006-81-3
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:34,494 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8006-81-3
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:34,830 INFO pino.train: Batch 189 | total=4.2854 | obj=0.2009 | season=1.3271 | wear=0.8101 | alignment=0.0036
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8047-24-3
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:34,847 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8047-24-3
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8032-35-1
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:34,887 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8032-35-1
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8032-35-1
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:34,925 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:34] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:34] SMILES Parse Error: check for mistakes around position 2:
[17:32:34] NATURAL:8032-35-1
[17:32:34] ~^
[17:32:34] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:35,197 INFO pino.train: Batch 190 | total=4.3832 | obj=0.1952 | season=1.4421 | wear=0.7332 | alignment=0.0014
[17:32:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:35] SMILES Parse Error: check for mistakes around position 2:
[17:32:35] NATURAL:8008-57-9
[17:32:35] ~^
[17:32:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:35,213 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:32:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:35] SMILES Parse Error: check for mistakes around position 2:
[17:32:35] NATURAL:8008-57-9
[17:32:35] ~^
[17:32:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:32:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:35] SMILES Parse Error: check for mistakes around position 2:
[17:32:35] NATURAL:8008-45-5
[17:32:35] ~^
[17:32:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:35,239 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:35] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:35] SMILES Parse Error: check for mistakes around position 2:
[17:32:35] NATURAL:8008-45-5
[17:32:35] ~^
[17:32:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:35,572 INFO pino.train: Batch 191 | total=4.2729 | obj=0.2028 | season=1.2888 | wear=0.8442 | alignment=0.0029
[17:32:35] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:35] SMILES Parse Error: check for mistakes around position 2:
[17:32:35] NATURAL:8013-76-1
[17:32:35] ~^
[17:32:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:35,602 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:35] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:35] SMILES Parse Error: check for mistakes around position 2:
[17:32:35] NATURAL:8013-76-1
[17:32:35] ~^
[17:32:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
[17:32:35] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:35] SMILES Parse Error: check for mistakes around position 2:
[17:32:35] NATURAL:68916-26-7
[17:32:35] ~^
[17:32:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:35,662 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:32:35] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:35] SMILES Parse Error: check for mistakes around position 2:
[17:32:35] NATURAL:68916-26-7
[17:32:35] ~^
[17:32:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:35,939 INFO pino.train: Batch 192 | total=4.2511 | obj=0.2005 | season=1.3886 | wear=0.7235 | alignment=0.0051
[17:32:35] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:35] SMILES Parse Error: check for mistakes around position 2:
[17:32:35] NATURAL:7462-86-6
[17:32:35] ~^
[17:32:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:35,993 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:35] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:35] SMILES Parse Error: check for mistakes around position 2:
[17:32:35] NATURAL:7462-86-6
[17:32:35] ~^
[17:32:35] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:36,219 INFO pino.train: Batch 193 | total=4.6086 | obj=0.2029 | season=1.4230 | wear=0.8749 | alignment=0.0021
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:85940-31-4
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:36,262 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:85940-31-4
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:8006-80-2
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:36,296 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:8006-80-2
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:36,576 INFO pino.train: Batch 194 | total=4.3311 | obj=0.2035 | season=1.3610 | wear=0.7974 | alignment=0.0041
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:85940-31-4
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:36,592 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:85940-31-4
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:7462-86-6
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:36,610 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:7462-86-6
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:8006-81-3
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:36,643 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:8006-81-3
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:8008-45-5
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:36,665 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:8008-45-5
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:8002-73-1
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:36,710 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:36] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:36] SMILES Parse Error: check for mistakes around position 2:
[17:32:36] NATURAL:8002-73-1
[17:32:36] ~^
[17:32:36] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:36,969 INFO pino.train: Batch 195 | total=4.0039 | obj=0.2040 | season=1.1449 | wear=0.8612 | alignment=0.0018
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8006-80-2
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:37,019 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8006-80-2
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:37,234 INFO pino.train: Batch 196 | total=4.7255 | obj=0.1979 | season=1.4545 | wear=0.9117 | alignment=0.0073
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8032-35-1
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:37,257 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8032-35-1
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8008-56-8
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:37,293 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8008-56-8
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8013-90-9
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:37,323 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8013-90-9
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8013-90-9
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:37,351 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8013-90-9
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:37,635 INFO pino.train: Batch 197 | total=3.9002 | obj=0.2052 | season=1.2126 | wear=0.7401 | alignment=0.0021
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8002-73-1
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:37,680 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8002-73-1
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:37,859 INFO pino.train: Batch 198 | total=4.3533 | obj=0.2052 | season=1.4296 | wear=0.7428 | alignment=0.0014
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8006-87-9
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:37,909 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8006-87-9
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8008-57-9
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:37,933 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8008-57-9
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8047-24-3
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:37,962 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:37] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:37] SMILES Parse Error: check for mistakes around position 2:
[17:32:37] NATURAL:8047-24-3
[17:32:37] ~^
[17:32:37] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:38,265 INFO pino.train: Batch 199 | total=3.5689 | obj=0.1985 | season=0.8945 | wear=0.8985 | alignment=0.0064
[17:32:38] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:38] SMILES Parse Error: check for mistakes around position 2:
[17:32:38] NATURAL:8015-77-8
[17:32:38] ~^
[17:32:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:38,286 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:32:38] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:38] SMILES Parse Error: check for mistakes around position 2:
[17:32:38] NATURAL:8015-77-8
[17:32:38] ~^
[17:32:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
[17:32:38] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:38] SMILES Parse Error: check for mistakes around position 2:
[17:32:38] NATURAL:89997-75-1
[17:32:38] ~^
[17:32:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:38,342 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:38] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:38] SMILES Parse Error: check for mistakes around position 2:
[17:32:38] NATURAL:89997-75-1
[17:32:38] ~^
[17:32:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:38,667 INFO pino.train: Batch 200 | total=4.3159 | obj=0.2013 | season=1.4280 | wear=0.7359 | alignment=0.0023
[17:32:38] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:38] SMILES Parse Error: check for mistakes around position 2:
[17:32:38] NATURAL:8006-87-9
[17:32:38] ~^
[17:32:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:38,726 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:38] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:38] SMILES Parse Error: check for mistakes around position 2:
[17:32:38] NATURAL:8006-87-9
[17:32:38] ~^
[17:32:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:32:38] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:38] SMILES Parse Error: check for mistakes around position 2:
[17:32:38] NATURAL:8013-76-1
[17:32:38] ~^
[17:32:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:38,769 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:38] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:38] SMILES Parse Error: check for mistakes around position 2:
[17:32:38] NATURAL:8013-76-1
[17:32:38] ~^
[17:32:38] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:39,027 INFO pino.train: Batch 201 | total=3.8011 | obj=0.2005 | season=1.1690 | wear=0.7384 | alignment=0.0012
2026-07-07 17:32:39,326 INFO pino.train: Batch 202 | total=4.4931 | obj=0.2024 | season=1.4734 | wear=0.7754 | alignment=0.0050
[17:32:39] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:39] SMILES Parse Error: check for mistakes around position 2:
[17:32:39] NATURAL:8006-87-9
[17:32:39] ~^
[17:32:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:39,379 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:39] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:39] SMILES Parse Error: check for mistakes around position 2:
[17:32:39] NATURAL:8006-87-9
[17:32:39] ~^
[17:32:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:32:39] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:39] SMILES Parse Error: check for mistakes around position 2:
[17:32:39] NATURAL:8047-24-3
[17:32:39] ~^
[17:32:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:39,404 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:39] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:39] SMILES Parse Error: check for mistakes around position 2:
[17:32:39] NATURAL:8047-24-3
[17:32:39] ~^
[17:32:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:39,706 INFO pino.train: Batch 203 | total=4.0607 | obj=0.2052 | season=1.3274 | wear=0.7013 | alignment=0.0041
2026-07-07 17:32:39,919 INFO pino.train: Batch 204 | total=4.4023 | obj=0.2001 | season=1.4066 | wear=0.7920 | alignment=0.0011
[17:32:39] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:39] SMILES Parse Error: check for mistakes around position 2:
[17:32:39] NATURAL:89997-75-1
[17:32:39] ~^
[17:32:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:39,944 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:39] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:39] SMILES Parse Error: check for mistakes around position 2:
[17:32:39] NATURAL:89997-75-1
[17:32:39] ~^
[17:32:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:32:39] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:39] SMILES Parse Error: check for mistakes around position 2:
[17:32:39] NATURAL:8002-73-1
[17:32:39] ~^
[17:32:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:39,971 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:39] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:39] SMILES Parse Error: check for mistakes around position 2:
[17:32:39] NATURAL:8002-73-1
[17:32:39] ~^
[17:32:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:39] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:39] SMILES Parse Error: check for mistakes around position 2:
[17:32:39] NATURAL:8002-73-1
[17:32:39] ~^
[17:32:39] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:40,002 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:8002-73-1
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:8008-31-9
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:40,053 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:8008-31-9
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:40,319 INFO pino.train: Batch 205 | total=4.2798 | obj=0.2068 | season=1.4056 | wear=0.7257 | alignment=0.0043
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:8002-73-1
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:40,362 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:8002-73-1
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:40,603 INFO pino.train: Batch 206 | total=4.5947 | obj=0.2001 | season=1.6032 | wear=0.6626 | alignment=0.0012
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:8006-80-2
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:40,655 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:8006-80-2
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:8002-73-1
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:40,676 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:8002-73-1
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:40,905 INFO pino.train: Batch 207 | total=4.4819 | obj=0.1921 | season=1.3746 | wear=0.8567 | alignment=0.0061
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:8008-31-9
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:40,953 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:8008-31-9
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:68916-26-7
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:40,979 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:32:40] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:40] SMILES Parse Error: check for mistakes around position 2:
[17:32:40] NATURAL:68916-26-7
[17:32:40] ~^
[17:32:40] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:41,325 INFO pino.train: Batch 208 | total=4.2874 | obj=0.2010 | season=1.3816 | wear=0.7457 | alignment=0.0035
2026-07-07 17:32:41,633 INFO pino.train: Batch 209 | total=3.9826 | obj=0.1940 | season=1.2126 | wear=0.7720 | alignment=0.0022
[17:32:41] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:41] SMILES Parse Error: check for mistakes around position 2:
[17:32:41] NATURAL:8032-35-1
[17:32:41] ~^
[17:32:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:41,679 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:41] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:41] SMILES Parse Error: check for mistakes around position 2:
[17:32:41] NATURAL:8032-35-1
[17:32:41] ~^
[17:32:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:41,855 INFO pino.train: Batch 210 | total=3.8592 | obj=0.2006 | season=1.2203 | wear=0.6992 | alignment=0.0011
[17:32:41] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:41] SMILES Parse Error: check for mistakes around position 2:
[17:32:41] NATURAL:8008-45-5
[17:32:41] ~^
[17:32:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:41,892 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:41] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:41] SMILES Parse Error: check for mistakes around position 2:
[17:32:41] NATURAL:8008-45-5
[17:32:41] ~^
[17:32:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:32:41] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:41] SMILES Parse Error: check for mistakes around position 2:
[17:32:41] NATURAL:8008-45-5
[17:32:41] ~^
[17:32:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:41,943 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:41] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:41] SMILES Parse Error: check for mistakes around position 2:
[17:32:41] NATURAL:8008-45-5
[17:32:41] ~^
[17:32:41] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:42,156 INFO pino.train: Batch 211 | total=4.7726 | obj=0.1953 | season=1.5137 | wear=0.8597 | alignment=0.0036
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:85409-36-9
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:42,195 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:85409-36-9
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:8002-73-1
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:42,224 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:8002-73-1
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:8013-76-1
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:42,268 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:8013-76-1
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:42,563 INFO pino.train: Batch 212 | total=3.8851 | obj=0.1985 | season=1.2043 | wear=0.7309 | alignment=0.0018
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:85940-31-4
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:42,594 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:85940-31-4
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:8047-24-3
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:42,628 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:8047-24-3
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:42,914 INFO pino.train: Batch 213 | total=4.5867 | obj=0.1974 | season=1.4849 | wear=0.7927 | alignment=0.0028
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:8008-57-9
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:42,947 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:8008-57-9
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:8006-87-9
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:42,978 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:8006-87-9
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:32:42] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:42] SMILES Parse Error: check for mistakes around position 2:
[17:32:42] NATURAL:8006-80-2
[17:32:42] ~^
[17:32:42] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:43,000 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:43] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:43] SMILES Parse Error: check for mistakes around position 2:
[17:32:43] NATURAL:8006-80-2
[17:32:43] ~^
[17:32:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:32:43] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:43] SMILES Parse Error: check for mistakes around position 2:
[17:32:43] NATURAL:8006-87-9
[17:32:43] ~^
[17:32:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:43,039 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:43] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:43] SMILES Parse Error: check for mistakes around position 2:
[17:32:43] NATURAL:8006-87-9
[17:32:43] ~^
[17:32:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:43,357 INFO pino.train: Batch 214 | total=3.9146 | obj=0.2036 | season=1.1423 | wear=0.8150 | alignment=0.0050
2026-07-07 17:32:43,567 INFO pino.train: Batch 215 | total=3.9069 | obj=0.2054 | season=1.1954 | wear=0.7567 | alignment=0.0022
[17:32:43] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:43] SMILES Parse Error: check for mistakes around position 2:
[17:32:43] NATURAL:8002-73-1
[17:32:43] ~^
[17:32:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:43,588 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:43] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:43] SMILES Parse Error: check for mistakes around position 2:
[17:32:43] NATURAL:8002-73-1
[17:32:43] ~^
[17:32:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:43] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:43] SMILES Parse Error: check for mistakes around position 2:
[17:32:43] NATURAL:7462-86-6
[17:32:43] ~^
[17:32:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:43,613 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:43] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:43] SMILES Parse Error: check for mistakes around position 2:
[17:32:43] NATURAL:7462-86-6
[17:32:43] ~^
[17:32:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:32:43] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:43] SMILES Parse Error: check for mistakes around position 2:
[17:32:43] NATURAL:89997-75-1
[17:32:43] ~^
[17:32:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:43,640 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:43] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:43] SMILES Parse Error: check for mistakes around position 2:
[17:32:43] NATURAL:89997-75-1
[17:32:43] ~^
[17:32:43] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:43,890 INFO pino.train: Batch 216 | total=4.7314 | obj=0.1988 | season=1.5076 | wear=0.8522 | alignment=0.0017
2026-07-07 17:32:44,226 INFO pino.train: Batch 217 | total=4.1327 | obj=0.1978 | season=1.2927 | wear=0.7702 | alignment=0.0028
2026-07-07 17:32:44,413 INFO pino.train: Batch 218 | total=4.5544 | obj=0.1971 | season=1.5201 | wear=0.7410 | alignment=0.0031
[17:32:44] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:44] SMILES Parse Error: check for mistakes around position 2:
[17:32:44] NATURAL:85409-36-9
[17:32:44] ~^
[17:32:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:44,464 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:44] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:44] SMILES Parse Error: check for mistakes around position 2:
[17:32:44] NATURAL:85409-36-9
[17:32:44] ~^
[17:32:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:32:44] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:44] SMILES Parse Error: check for mistakes around position 2:
[17:32:44] NATURAL:8002-73-1
[17:32:44] ~^
[17:32:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:44,500 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:44] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:44] SMILES Parse Error: check for mistakes around position 2:
[17:32:44] NATURAL:8002-73-1
[17:32:44] ~^
[17:32:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:44,733 INFO pino.train: Batch 219 | total=3.9847 | obj=0.2038 | season=1.2318 | wear=0.7548 | alignment=0.0038
[17:32:44] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:44] SMILES Parse Error: check for mistakes around position 2:
[17:32:44] NATURAL:8013-76-1
[17:32:44] ~^
[17:32:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:44,759 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:44] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:44] SMILES Parse Error: check for mistakes around position 2:
[17:32:44] NATURAL:8013-76-1
[17:32:44] ~^
[17:32:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
[17:32:44] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:44] SMILES Parse Error: check for mistakes around position 2:
[17:32:44] NATURAL:8047-24-3
[17:32:44] ~^
[17:32:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:44,791 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:44] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:44] SMILES Parse Error: check for mistakes around position 2:
[17:32:44] NATURAL:8047-24-3
[17:32:44] ~^
[17:32:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:32:44] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:44] SMILES Parse Error: check for mistakes around position 2:
[17:32:44] NATURAL:68916-26-7
[17:32:44] ~^
[17:32:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:44,824 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:32:44] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:44] SMILES Parse Error: check for mistakes around position 2:
[17:32:44] NATURAL:68916-26-7
[17:32:44] ~^
[17:32:44] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:45,078 INFO pino.train: Batch 220 | total=3.8322 | obj=0.2063 | season=1.1429 | wear=0.7733 | alignment=0.0055
[17:32:45] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:45] SMILES Parse Error: check for mistakes around position 2:
[17:32:45] NATURAL:8008-31-9
[17:32:45] ~^
[17:32:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:45,130 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:32:45] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:45] SMILES Parse Error: check for mistakes around position 2:
[17:32:45] NATURAL:8008-31-9
[17:32:45] ~^
[17:32:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:32:45] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:45] SMILES Parse Error: check for mistakes around position 2:
[17:32:45] NATURAL:8002-73-1
[17:32:45] ~^
[17:32:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:45,180 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:45] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:45] SMILES Parse Error: check for mistakes around position 2:
[17:32:45] NATURAL:8002-73-1
[17:32:45] ~^
[17:32:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:45,470 INFO pino.train: Batch 221 | total=4.2198 | obj=0.2012 | season=1.2062 | wear=0.9107 | alignment=0.0051
[17:32:45] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:45] SMILES Parse Error: check for mistakes around position 2:
[17:32:45] NATURAL:8013-76-1
[17:32:45] ~^
[17:32:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:32:45,503 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:32:45] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:32:45] SMILES Parse Error: check for mistakes around position 2:
[17:32:45] NATURAL:8013-76-1
[17:32:45] ~^
[17:32:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
[17:32:45] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:45] SMILES Parse Error: check for mistakes around position 2:
[17:32:45] NATURAL:68916-26-7
[17:32:45] ~^
[17:32:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:45,571 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:32:45] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:32:45] SMILES Parse Error: check for mistakes around position 2:
[17:32:45] NATURAL:68916-26-7
[17:32:45] ~^
[17:32:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:32:45,858 INFO pino.train: Batch 222 | total=4.7522 | obj=0.1954 | season=1.5556 | wear=0.8188 | alignment=0.0033
[17:32:45] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:45] SMILES Parse Error: check for mistakes around position 2:
[17:32:45] NATURAL:8002-73-1
[17:32:45] ~^
[17:32:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:45,878 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:45] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:45] SMILES Parse Error: check for mistakes around position 2:
[17:32:45] NATURAL:8002-73-1
[17:32:45] ~^
[17:32:45] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:46,170 INFO pino.train: Batch 223 | total=5.0167 | obj=0.1905 | season=1.7359 | wear=0.7496 | alignment=0.0023
[17:32:46] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:46] SMILES Parse Error: check for mistakes around position 2:
[17:32:46] NATURAL:8015-77-8
[17:32:46] ~^
[17:32:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:46,197 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:32:46] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:46] SMILES Parse Error: check for mistakes around position 2:
[17:32:46] NATURAL:8015-77-8
[17:32:46] ~^
[17:32:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:46,522 INFO pino.train: Batch 224 | total=4.2728 | obj=0.2029 | season=1.3865 | wear=0.7341 | alignment=0.0021
[17:32:46] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:46] SMILES Parse Error: check for mistakes around position 2:
[17:32:46] NATURAL:89997-75-1
[17:32:46] ~^
[17:32:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:46,551 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:46] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:46] SMILES Parse Error: check for mistakes around position 2:
[17:32:46] NATURAL:89997-75-1
[17:32:46] ~^
[17:32:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:32:46] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:46] SMILES Parse Error: check for mistakes around position 2:
[17:32:46] NATURAL:7462-86-6
[17:32:46] ~^
[17:32:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:46,573 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:46] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:46] SMILES Parse Error: check for mistakes around position 2:
[17:32:46] NATURAL:7462-86-6
[17:32:46] ~^
[17:32:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:46,876 INFO pino.train: Batch 225 | total=4.7669 | obj=0.2026 | season=1.5794 | wear=0.7773 | alignment=0.0018
[17:32:46] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:46] SMILES Parse Error: check for mistakes around position 2:
[17:32:46] NATURAL:8008-56-8
[17:32:46] ~^
[17:32:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:46,928 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:32:46] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:46] SMILES Parse Error: check for mistakes around position 2:
[17:32:46] NATURAL:8008-56-8
[17:32:46] ~^
[17:32:46] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:47,221 INFO pino.train: Batch 226 | total=4.1534 | obj=0.2036 | season=1.2862 | wear=0.7777 | alignment=0.0019
2026-07-07 17:32:47,490 INFO pino.train: Batch 227 | total=5.0955 | obj=0.1990 | season=1.6931 | wear=0.8210 | alignment=0.0026
[17:32:47] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:47] SMILES Parse Error: check for mistakes around position 2:
[17:32:47] NATURAL:8006-87-9
[17:32:47] ~^
[17:32:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:47,559 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:47] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:47] SMILES Parse Error: check for mistakes around position 2:
[17:32:47] NATURAL:8006-87-9
[17:32:47] ~^
[17:32:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:32:47] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:47] SMILES Parse Error: check for mistakes around position 2:
[17:32:47] NATURAL:8047-24-3
[17:32:47] ~^
[17:32:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:32:47,585 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:32:47] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:32:47] SMILES Parse Error: check for mistakes around position 2:
[17:32:47] NATURAL:8047-24-3
[17:32:47] ~^
[17:32:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:32:47] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:47] SMILES Parse Error: check for mistakes around position 2:
[17:32:47] NATURAL:85409-36-9
[17:32:47] ~^
[17:32:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:47,609 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:47] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:47] SMILES Parse Error: check for mistakes around position 2:
[17:32:47] NATURAL:85409-36-9
[17:32:47] ~^
[17:32:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:47,871 INFO pino.train: Batch 228 | total=4.1793 | obj=0.1963 | season=1.2245 | wear=0.8596 | alignment=0.0038
[17:32:47] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:47] SMILES Parse Error: check for mistakes around position 2:
[17:32:47] NATURAL:85409-36-9
[17:32:47] ~^
[17:32:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:47,948 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:47] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:47] SMILES Parse Error: check for mistakes around position 2:
[17:32:47] NATURAL:85409-36-9
[17:32:47] ~^
[17:32:47] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:48,190 INFO pino.train: Batch 229 | total=4.4810 | obj=0.1953 | season=1.4522 | wear=0.7684 | alignment=0.0029
2026-07-07 17:32:48,497 INFO pino.train: Batch 230 | total=4.0096 | obj=0.2006 | season=1.2036 | wear=0.7952 | alignment=0.0029
[17:32:48] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:48] SMILES Parse Error: check for mistakes around position 2:
[17:32:48] NATURAL:8002-73-1
[17:32:48] ~^
[17:32:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:48,519 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:48] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:48] SMILES Parse Error: check for mistakes around position 2:
[17:32:48] NATURAL:8002-73-1
[17:32:48] ~^
[17:32:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:48] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:48] SMILES Parse Error: check for mistakes around position 2:
[17:32:48] NATURAL:89997-75-1
[17:32:48] ~^
[17:32:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:48,575 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:48] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:48] SMILES Parse Error: check for mistakes around position 2:
[17:32:48] NATURAL:89997-75-1
[17:32:48] ~^
[17:32:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:32:48] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:32:48] SMILES Parse Error: check for mistakes around position 2:
[17:32:48] NATURAL:8015-61-0
[17:32:48] ~^
[17:32:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:32:48,600 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:32:48] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:32:48] SMILES Parse Error: check for mistakes around position 2:
[17:32:48] NATURAL:8015-61-0
[17:32:48] ~^
[17:32:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:32:48,906 INFO pino.train: Batch 231 | total=4.9532 | obj=0.1999 | season=1.6930 | wear=0.7473 | alignment=0.0022
[17:32:48] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:48] SMILES Parse Error: check for mistakes around position 2:
[17:32:48] NATURAL:85940-31-4
[17:32:48] ~^
[17:32:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:48,922 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:48] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:48] SMILES Parse Error: check for mistakes around position 2:
[17:32:48] NATURAL:85940-31-4
[17:32:48] ~^
[17:32:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:32:48] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:48] SMILES Parse Error: check for mistakes around position 2:
[17:32:48] NATURAL:89997-75-1
[17:32:48] ~^
[17:32:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:48,990 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:48] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:48] SMILES Parse Error: check for mistakes around position 2:
[17:32:48] NATURAL:89997-75-1
[17:32:48] ~^
[17:32:48] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:49,312 INFO pino.train: Batch 232 | total=4.4545 | obj=0.2092 | season=1.4441 | wear=0.7564 | alignment=0.0027
[17:32:49] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:49] SMILES Parse Error: check for mistakes around position 2:
[17:32:49] NATURAL:85940-31-4
[17:32:49] ~^
[17:32:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:49,355 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:49] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:49] SMILES Parse Error: check for mistakes around position 2:
[17:32:49] NATURAL:85940-31-4
[17:32:49] ~^
[17:32:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:49,667 INFO pino.train: Batch 233 | total=4.1099 | obj=0.1984 | season=1.2265 | wear=0.8192 | alignment=0.0018
2026-07-07 17:32:49,946 INFO pino.train: Batch 234 | total=4.3786 | obj=0.2043 | season=1.4037 | wear=0.7658 | alignment=0.0019
[17:32:49] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:49] SMILES Parse Error: check for mistakes around position 2:
[17:32:49] NATURAL:8002-73-1
[17:32:49] ~^
[17:32:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:49,967 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:49] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:49] SMILES Parse Error: check for mistakes around position 2:
[17:32:49] NATURAL:8002-73-1
[17:32:49] ~^
[17:32:49] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:8006-81-3
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:50,033 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:8006-81-3
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:7462-86-6
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:50,049 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:7462-86-6
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:50,303 INFO pino.train: Batch 235 | total=4.0016 | obj=0.2065 | season=1.2224 | wear=0.7686 | alignment=0.0036
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:8002-73-1
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:50,344 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:8002-73-1
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:8002-73-1
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:50,378 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:8002-73-1
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:8013-90-9
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:50,415 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:8013-90-9
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:50,665 INFO pino.train: Batch 236 | total=3.9773 | obj=0.2019 | season=1.2801 | wear=0.6922 | alignment=0.0032
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:8032-35-1
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:32:50,688 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:8032-35-1
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:7462-86-6
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:50,702 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:50] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:50] SMILES Parse Error: check for mistakes around position 2:
[17:32:50] NATURAL:7462-86-6
[17:32:50] ~^
[17:32:50] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:51,041 INFO pino.train: Batch 237 | total=4.3613 | obj=0.2039 | season=1.4101 | wear=0.7500 | alignment=0.0015
2026-07-07 17:32:51,332 INFO pino.train: Batch 238 | total=4.5037 | obj=0.1996 | season=1.4732 | wear=0.7526 | alignment=0.0058
[17:32:51] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:51] SMILES Parse Error: check for mistakes around position 2:
[17:32:51] NATURAL:7462-86-6
[17:32:51] ~^
[17:32:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:51,398 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:51] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:51] SMILES Parse Error: check for mistakes around position 2:
[17:32:51] NATURAL:7462-86-6
[17:32:51] ~^
[17:32:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:51,654 INFO pino.train: Batch 239 | total=4.4325 | obj=0.1996 | season=1.4219 | wear=0.7709 | alignment=0.0042
[17:32:51] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:51] SMILES Parse Error: check for mistakes around position 2:
[17:32:51] NATURAL:8006-81-3
[17:32:51] ~^
[17:32:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:51,711 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:51] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:51] SMILES Parse Error: check for mistakes around position 2:
[17:32:51] NATURAL:8006-81-3
[17:32:51] ~^
[17:32:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
[17:32:51] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:51] SMILES Parse Error: check for mistakes around position 2:
[17:32:51] NATURAL:8008-57-9
[17:32:51] ~^
[17:32:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:51,734 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:32:51] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:51] SMILES Parse Error: check for mistakes around position 2:
[17:32:51] NATURAL:8008-57-9
[17:32:51] ~^
[17:32:51] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:52,002 INFO pino.train: Batch 240 | total=4.3166 | obj=0.2089 | season=1.3569 | wear=0.7826 | alignment=0.0022
2026-07-07 17:32:52,264 INFO pino.train: Batch 241 | total=4.3217 | obj=0.1988 | season=1.3247 | wear=0.8237 | alignment=0.0018
2026-07-07 17:32:52,595 INFO pino.train: Batch 242 | total=4.0795 | obj=0.1970 | season=1.2776 | wear=0.7494 | alignment=0.0067
[17:32:52] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:52] SMILES Parse Error: check for mistakes around position 2:
[17:32:52] NATURAL:8008-57-9
[17:32:52] ~^
[17:32:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:52,637 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:32:52] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:32:52] SMILES Parse Error: check for mistakes around position 2:
[17:32:52] NATURAL:8008-57-9
[17:32:52] ~^
[17:32:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:32:52,813 INFO pino.train: Batch 243 | total=3.9943 | obj=0.2018 | season=1.1893 | wear=0.8042 | alignment=0.0032
[17:32:52] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:52] SMILES Parse Error: check for mistakes around position 2:
[17:32:52] NATURAL:8002-73-1
[17:32:52] ~^
[17:32:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:52,854 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:52] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:52] SMILES Parse Error: check for mistakes around position 2:
[17:32:52] NATURAL:8002-73-1
[17:32:52] ~^
[17:32:52] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:53,092 INFO pino.train: Batch 244 | total=4.4633 | obj=0.1992 | season=1.4373 | wear=0.7807 | alignment=0.0020
2026-07-07 17:32:53,339 INFO pino.train: Batch 245 | total=4.2231 | obj=0.2008 | season=1.3681 | wear=0.7280 | alignment=0.0061
2026-07-07 17:32:53,701 INFO pino.train: Batch 246 | total=4.1980 | obj=0.2016 | season=1.2997 | wear=0.7903 | alignment=0.0007
[17:32:53] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:53] SMILES Parse Error: check for mistakes around position 2:
[17:32:53] NATURAL:85940-31-4
[17:32:53] ~^
[17:32:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:53,757 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:53] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:53] SMILES Parse Error: check for mistakes around position 2:
[17:32:53] NATURAL:85940-31-4
[17:32:53] ~^
[17:32:53] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:53,997 INFO pino.train: Batch 247 | total=3.7721 | obj=0.2022 | season=1.1569 | wear=0.7235 | alignment=0.0015
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:85409-36-9
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:32:54,055 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:85409-36-9
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:7462-86-6
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:54,071 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:7462-86-6
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:54,301 INFO pino.train: Batch 248 | total=3.9342 | obj=0.2018 | season=1.2265 | wear=0.7343 | alignment=0.0018
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:8015-77-8
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:32:54,379 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:8015-77-8
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:8013-90-9
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:54,401 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:8013-90-9
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:54,655 INFO pino.train: Batch 249 | total=4.1783 | obj=0.1997 | season=1.2610 | wear=0.8271 | alignment=0.0041
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:8002-73-1
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:54,723 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:8002-73-1
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:7462-86-6
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:54,744 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:54] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:54] SMILES Parse Error: check for mistakes around position 2:
[17:32:54] NATURAL:7462-86-6
[17:32:54] ~^
[17:32:54] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:55,022 INFO pino.train: Batch 250 | total=4.0792 | obj=0.1967 | season=1.2169 | wear=0.8252 | alignment=0.0023
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8008-45-5
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:32:55,039 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8008-45-5
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8002-73-1
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:55,096 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8002-73-1
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:55,266 INFO pino.train: Batch 251 | total=3.9797 | obj=0.2062 | season=1.2562 | wear=0.7330 | alignment=0.0008
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8006-81-3
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:55,298 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8006-81-3
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:55,604 INFO pino.train: Batch 252 | total=5.3583 | obj=0.2008 | season=1.8707 | wear=0.7786 | alignment=0.0052
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8006-80-2
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:55,650 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8006-80-2
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8002-73-1
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:55,700 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8002-73-1
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:55,921 INFO pino.train: Batch 253 | total=4.8014 | obj=0.2008 | season=1.6179 | wear=0.7509 | alignment=0.0043
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8008-31-9
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:32:55,980 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8008-31-9
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:32:55] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:55] SMILES Parse Error: check for mistakes around position 2:
[17:32:55] NATURAL:8008-56-8
[17:32:55] ~^
[17:32:55] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:56,004 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:32:56] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:56] SMILES Parse Error: check for mistakes around position 2:
[17:32:56] NATURAL:8008-56-8
[17:32:56] ~^
[17:32:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:56,240 INFO pino.train: Batch 254 | total=4.2018 | obj=0.1954 | season=1.2601 | wear=0.8326 | alignment=0.0029
[17:32:56] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:56] SMILES Parse Error: check for mistakes around position 2:
[17:32:56] NATURAL:8008-56-8
[17:32:56] ~^
[17:32:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:32:56,353 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:32:56] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:32:56] SMILES Parse Error: check for mistakes around position 2:
[17:32:56] NATURAL:8008-56-8
[17:32:56] ~^
[17:32:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:32:56] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:56] SMILES Parse Error: check for mistakes around position 2:
[17:32:56] NATURAL:89997-75-1
[17:32:56] ~^
[17:32:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:32:56,401 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:32:56] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:32:56] SMILES Parse Error: check for mistakes around position 2:
[17:32:56] NATURAL:89997-75-1
[17:32:56] ~^
[17:32:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:32:56] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:56] SMILES Parse Error: check for mistakes around position 2:
[17:32:56] NATURAL:8006-87-9
[17:32:56] ~^
[17:32:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:56,443 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:32:56] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:32:56] SMILES Parse Error: check for mistakes around position 2:
[17:32:56] NATURAL:8006-87-9
[17:32:56] ~^
[17:32:56] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:32:56,782 INFO pino.train: Batch 255 | total=5.1803 | obj=0.2019 | season=1.7402 | wear=0.8133 | alignment=0.0015
2026-07-07 17:32:57,166 INFO pino.train: Batch 256 | total=4.4805 | obj=0.2019 | season=1.4415 | wear=0.7725 | alignment=0.0016
[17:32:57] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:57] SMILES Parse Error: check for mistakes around position 2:
[17:32:57] NATURAL:8006-81-3
[17:32:57] ~^
[17:32:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:57,189 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:32:57] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:32:57] SMILES Parse Error: check for mistakes around position 2:
[17:32:57] NATURAL:8006-81-3
[17:32:57] ~^
[17:32:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:32:57,533 INFO pino.train: Batch 257 | total=4.0362 | obj=0.1947 | season=1.2706 | wear=0.7280 | alignment=0.0029
[17:32:57] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:57] SMILES Parse Error: check for mistakes around position 2:
[17:32:57] NATURAL:85940-31-4
[17:32:57] ~^
[17:32:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:57,609 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:32:57] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:32:57] SMILES Parse Error: check for mistakes around position 2:
[17:32:57] NATURAL:85940-31-4
[17:32:57] ~^
[17:32:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:32:57,900 INFO pino.train: Batch 258 | total=4.0600 | obj=0.1961 | season=1.1947 | wear=0.8288 | alignment=0.0022
[17:32:57] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:57] SMILES Parse Error: check for mistakes around position 2:
[17:32:57] NATURAL:7462-86-6
[17:32:57] ~^
[17:32:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:57,922 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:32:57] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:32:57] SMILES Parse Error: check for mistakes around position 2:
[17:32:57] NATURAL:7462-86-6
[17:32:57] ~^
[17:32:57] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:32:58,198 INFO pino.train: Batch 259 | total=4.3021 | obj=0.2000 | season=1.3161 | wear=0.8267 | alignment=0.0042
[17:32:58] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:58] SMILES Parse Error: check for mistakes around position 2:
[17:32:58] NATURAL:8002-73-1
[17:32:58] ~^
[17:32:58] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:58,219 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:58] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:58] SMILES Parse Error: check for mistakes around position 2:
[17:32:58] NATURAL:8002-73-1
[17:32:58] ~^
[17:32:58] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:58,529 INFO pino.train: Batch 260 | total=4.2133 | obj=0.1957 | season=1.2654 | wear=0.8379 | alignment=0.0012
2026-07-07 17:32:59,045 INFO pino.train: Batch 261 | total=5.1007 | obj=0.2002 | season=1.7383 | wear=0.7822 | alignment=0.0037
[17:32:59] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:59] SMILES Parse Error: check for mistakes around position 2:
[17:32:59] NATURAL:8002-73-1
[17:32:59] ~^
[17:32:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:59,078 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:59] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:59] SMILES Parse Error: check for mistakes around position 2:
[17:32:59] NATURAL:8002-73-1
[17:32:59] ~^
[17:32:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:32:59] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:59] SMILES Parse Error: check for mistakes around position 2:
[17:32:59] NATURAL:8002-73-1
[17:32:59] ~^
[17:32:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:59,167 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:59] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:59] SMILES Parse Error: check for mistakes around position 2:
[17:32:59] NATURAL:8002-73-1
[17:32:59] ~^
[17:32:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:59,681 INFO pino.train: Batch 262 | total=4.3147 | obj=0.2004 | season=1.4131 | wear=0.7202 | alignment=0.0014
[17:32:59] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:59] SMILES Parse Error: check for mistakes around position 2:
[17:32:59] NATURAL:8013-90-9
[17:32:59] ~^
[17:32:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:32:59,718 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:32:59] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:32:59] SMILES Parse Error: check for mistakes around position 2:
[17:32:59] NATURAL:8013-90-9
[17:32:59] ~^
[17:32:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:32:59] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:59] SMILES Parse Error: check for mistakes around position 2:
[17:32:59] NATURAL:8006-80-2
[17:32:59] ~^
[17:32:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:32:59,769 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:32:59] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:32:59] SMILES Parse Error: check for mistakes around position 2:
[17:32:59] NATURAL:8006-80-2
[17:32:59] ~^
[17:32:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:32:59] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:59] SMILES Parse Error: check for mistakes around position 2:
[17:32:59] NATURAL:8002-73-1
[17:32:59] ~^
[17:32:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:32:59,846 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:32:59] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:32:59] SMILES Parse Error: check for mistakes around position 2:
[17:32:59] NATURAL:8002-73-1
[17:32:59] ~^
[17:32:59] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:00,267 INFO pino.train: Batch 263 | total=4.0733 | obj=0.2033 | season=1.2260 | wear=0.8025 | alignment=0.0064
[17:33:00] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:00] SMILES Parse Error: check for mistakes around position 2:
[17:33:00] NATURAL:8002-73-1
[17:33:00] ~^
[17:33:00] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:00,311 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:00] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:00] SMILES Parse Error: check for mistakes around position 2:
[17:33:00] NATURAL:8002-73-1
[17:33:00] ~^
[17:33:00] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:00,548 INFO pino.train: Batch 264 | total=3.9840 | obj=0.1993 | season=1.2107 | wear=0.7750 | alignment=0.0028
2026-07-07 17:33:00,884 INFO pino.train: Batch 265 | total=4.8843 | obj=0.1993 | season=1.5878 | wear=0.8359 | alignment=0.0038
[17:33:00] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:00] SMILES Parse Error: check for mistakes around position 2:
[17:33:00] NATURAL:85940-31-4
[17:33:00] ~^
[17:33:00] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:00,921 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:33:00] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:00] SMILES Parse Error: check for mistakes around position 2:
[17:33:00] NATURAL:85940-31-4
[17:33:00] ~^
[17:33:00] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:01,106 INFO pino.train: Batch 266 | total=4.3489 | obj=0.1974 | season=1.4345 | wear=0.7172 | alignment=0.0040
2026-07-07 17:33:01,450 INFO pino.train: Batch 267 | total=4.1785 | obj=0.1995 | season=1.1741 | wear=0.9170 | alignment=0.0034
[17:33:01] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:01] SMILES Parse Error: check for mistakes around position 2:
[17:33:01] NATURAL:8002-73-1
[17:33:01] ~^
[17:33:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:01,481 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:01] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:01] SMILES Parse Error: check for mistakes around position 2:
[17:33:01] NATURAL:8002-73-1
[17:33:01] ~^
[17:33:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:01,779 INFO pino.train: Batch 268 | total=4.2702 | obj=0.2014 | season=1.3955 | wear=0.7262 | alignment=0.0014
[17:33:01] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:33:01] SMILES Parse Error: check for mistakes around position 2:
[17:33:01] NATURAL:8015-77-8
[17:33:01] ~^
[17:33:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:33:01,832 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:33:01] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:33:01] SMILES Parse Error: check for mistakes around position 2:
[17:33:01] NATURAL:8015-77-8
[17:33:01] ~^
[17:33:01] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:33:02,151 INFO pino.train: Batch 269 | total=4.7600 | obj=0.1987 | season=1.5902 | wear=0.7645 | alignment=0.0038
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:8002-73-1
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:02,190 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:8002-73-1
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:89997-75-1
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:02,228 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:89997-75-1
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:8002-73-1
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:02,252 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:8002-73-1
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:02,463 INFO pino.train: Batch 270 | total=4.0265 | obj=0.2018 | season=1.3116 | wear=0.6805 | alignment=0.0010
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:85940-31-4
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:02,495 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:85940-31-4
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:02,811 INFO pino.train: Batch 271 | total=4.0514 | obj=0.2013 | season=1.2999 | wear=0.7056 | alignment=0.0024
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:8008-56-8
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:33:02,828 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:8008-56-8
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:8015-61-0
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:33:02,855 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:33:02] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:33:02] SMILES Parse Error: check for mistakes around position 2:
[17:33:02] NATURAL:8015-61-0
[17:33:02] ~^
[17:33:02] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:33:03,068 INFO pino.train: Batch 272 | total=3.9526 | obj=0.1937 | season=1.2192 | wear=0.7445 | alignment=0.0023
2026-07-07 17:33:03,386 INFO pino.train: Batch 273 | total=4.1402 | obj=0.1997 | season=1.3236 | wear=0.7284 | alignment=0.0027
[17:33:03] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:03] SMILES Parse Error: check for mistakes around position 2:
[17:33:03] NATURAL:8002-73-1
[17:33:03] ~^
[17:33:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:03,445 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:03] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:03] SMILES Parse Error: check for mistakes around position 2:
[17:33:03] NATURAL:8002-73-1
[17:33:03] ~^
[17:33:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:03,700 INFO pino.train: Batch 274 | total=4.3480 | obj=0.1978 | season=1.3505 | wear=0.8102 | alignment=0.0023
[17:33:03] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:03] SMILES Parse Error: check for mistakes around position 2:
[17:33:03] NATURAL:8013-90-9
[17:33:03] ~^
[17:33:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:03,726 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:33:03] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:03] SMILES Parse Error: check for mistakes around position 2:
[17:33:03] NATURAL:8013-90-9
[17:33:03] ~^
[17:33:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:33:03] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:03] SMILES Parse Error: check for mistakes around position 2:
[17:33:03] NATURAL:89997-75-1
[17:33:03] ~^
[17:33:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:03,754 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:33:03] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:03] SMILES Parse Error: check for mistakes around position 2:
[17:33:03] NATURAL:89997-75-1
[17:33:03] ~^
[17:33:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:33:03] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:03] SMILES Parse Error: check for mistakes around position 2:
[17:33:03] NATURAL:8002-73-1
[17:33:03] ~^
[17:33:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:03,793 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:03] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:03] SMILES Parse Error: check for mistakes around position 2:
[17:33:03] NATURAL:8002-73-1
[17:33:03] ~^
[17:33:03] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:04,007 INFO pino.train: Batch 275 | total=3.9740 | obj=0.1982 | season=1.2101 | wear=0.7694 | alignment=0.0033
[17:33:04] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:04] SMILES Parse Error: check for mistakes around position 2:
[17:33:04] NATURAL:8002-73-1
[17:33:04] ~^
[17:33:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:04,078 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:04] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:04] SMILES Parse Error: check for mistakes around position 2:
[17:33:04] NATURAL:8002-73-1
[17:33:04] ~^
[17:33:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:04,360 INFO pino.train: Batch 276 | total=4.0105 | obj=0.2017 | season=1.2165 | wear=0.7845 | alignment=0.0048
[17:33:04] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:04] SMILES Parse Error: check for mistakes around position 2:
[17:33:04] NATURAL:8013-90-9
[17:33:04] ~^
[17:33:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:04,396 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:33:04] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:04] SMILES Parse Error: check for mistakes around position 2:
[17:33:04] NATURAL:8013-90-9
[17:33:04] ~^
[17:33:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:33:04] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:04] SMILES Parse Error: check for mistakes around position 2:
[17:33:04] NATURAL:89997-75-1
[17:33:04] ~^
[17:33:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:04,463 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:33:04] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:04] SMILES Parse Error: check for mistakes around position 2:
[17:33:04] NATURAL:89997-75-1
[17:33:04] ~^
[17:33:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:04,772 INFO pino.train: Batch 277 | total=4.5024 | obj=0.2096 | season=1.4399 | wear=0.8006 | alignment=0.0034
[17:33:04] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:04] SMILES Parse Error: check for mistakes around position 2:
[17:33:04] NATURAL:68916-26-7
[17:33:04] ~^
[17:33:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:33:04,809 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:33:04] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:04] SMILES Parse Error: check for mistakes around position 2:
[17:33:04] NATURAL:68916-26-7
[17:33:04] ~^
[17:33:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:33:04] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:04] SMILES Parse Error: check for mistakes around position 2:
[17:33:04] NATURAL:8006-81-3
[17:33:04] ~^
[17:33:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:04,870 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:33:04] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:04] SMILES Parse Error: check for mistakes around position 2:
[17:33:04] NATURAL:8006-81-3
[17:33:04] ~^
[17:33:04] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:05,107 INFO pino.train: Batch 278 | total=3.9717 | obj=0.2031 | season=1.1734 | wear=0.8126 | alignment=0.0018
[17:33:05] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:05] SMILES Parse Error: check for mistakes around position 2:
[17:33:05] NATURAL:8006-81-3
[17:33:05] ~^
[17:33:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:05,175 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:33:05] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:05] SMILES Parse Error: check for mistakes around position 2:
[17:33:05] NATURAL:8006-81-3
[17:33:05] ~^
[17:33:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:05,419 INFO pino.train: Batch 279 | total=3.9799 | obj=0.1988 | season=1.2474 | wear=0.7395 | alignment=0.0026
[17:33:05] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:33:05] SMILES Parse Error: check for mistakes around position 2:
[17:33:05] NATURAL:8013-76-1
[17:33:05] ~^
[17:33:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:33:05,454 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:33:05] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:33:05] SMILES Parse Error: check for mistakes around position 2:
[17:33:05] NATURAL:8013-76-1
[17:33:05] ~^
[17:33:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
[17:33:05] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:05] SMILES Parse Error: check for mistakes around position 2:
[17:33:05] NATURAL:68916-26-7
[17:33:05] ~^
[17:33:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:33:05,505 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:33:05] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:05] SMILES Parse Error: check for mistakes around position 2:
[17:33:05] NATURAL:68916-26-7
[17:33:05] ~^
[17:33:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:33:05,817 INFO pino.train: Batch 280 | total=4.3375 | obj=0.2001 | season=1.4251 | wear=0.7325 | alignment=0.0015
[17:33:05] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:05] SMILES Parse Error: check for mistakes around position 2:
[17:33:05] NATURAL:8002-73-1
[17:33:05] ~^
[17:33:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:05,836 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:05] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:05] SMILES Parse Error: check for mistakes around position 2:
[17:33:05] NATURAL:8002-73-1
[17:33:05] ~^
[17:33:05] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:06,104 INFO pino.train: Batch 281 | total=4.0904 | obj=0.2007 | season=1.2311 | wear=0.8138 | alignment=0.0071
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8013-90-9
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:06,157 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8013-90-9
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8006-80-2
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:06,183 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8006-80-2
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8047-24-3
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:06,213 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8047-24-3
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:06,426 INFO pino.train: Batch 282 | total=4.0435 | obj=0.1972 | season=1.2594 | wear=0.7607 | alignment=0.0026
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8002-73-1
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:06,467 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8002-73-1
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8006-80-2
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:06,504 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8006-80-2
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:06,718 INFO pino.train: Batch 283 | total=3.9651 | obj=0.2056 | season=1.1871 | wear=0.7987 | alignment=0.0047
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8008-45-5
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:33:06,816 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:33:06] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:33:06] SMILES Parse Error: check for mistakes around position 2:
[17:33:06] NATURAL:8008-45-5
[17:33:06] ~^
[17:33:06] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:33:07,097 INFO pino.train: Batch 284 | total=4.2727 | obj=0.2040 | season=1.3520 | wear=0.7850 | alignment=0.0035
[17:33:07] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:07] SMILES Parse Error: check for mistakes around position 2:
[17:33:07] NATURAL:8006-87-9
[17:33:07] ~^
[17:33:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:33:07,124 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:33:07] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:07] SMILES Parse Error: check for mistakes around position 2:
[17:33:07] NATURAL:8006-87-9
[17:33:07] ~^
[17:33:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:33:07] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:07] SMILES Parse Error: check for mistakes around position 2:
[17:33:07] NATURAL:8006-81-3
[17:33:07] ~^
[17:33:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:07,154 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:33:07] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:07] SMILES Parse Error: check for mistakes around position 2:
[17:33:07] NATURAL:8006-81-3
[17:33:07] ~^
[17:33:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
[17:33:07] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:33:07] SMILES Parse Error: check for mistakes around position 2:
[17:33:07] NATURAL:8008-56-8
[17:33:07] ~^
[17:33:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:33:07,185 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:33:07] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:33:07] SMILES Parse Error: check for mistakes around position 2:
[17:33:07] NATURAL:8008-56-8
[17:33:07] ~^
[17:33:07] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:33:07,447 INFO pino.train: Batch 285 | total=3.8436 | obj=0.1960 | season=1.1669 | wear=0.7587 | alignment=0.0026
[17:33:08] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:08] SMILES Parse Error: check for mistakes around position 2:
[17:33:08] NATURAL:8047-24-3
[17:33:08] ~^
[17:33:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:08,242 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:33:08] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:08] SMILES Parse Error: check for mistakes around position 2:
[17:33:08] NATURAL:8047-24-3
[17:33:08] ~^
[17:33:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:33:08] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:08] SMILES Parse Error: check for mistakes around position 2:
[17:33:08] NATURAL:68916-26-7
[17:33:08] ~^
[17:33:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:33:08,265 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:33:08] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:08] SMILES Parse Error: check for mistakes around position 2:
[17:33:08] NATURAL:68916-26-7
[17:33:08] ~^
[17:33:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:33:08] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:33:08] SMILES Parse Error: check for mistakes around position 2:
[17:33:08] NATURAL:8015-77-8
[17:33:08] ~^
[17:33:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:33:08,309 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:33:08] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:33:08] SMILES Parse Error: check for mistakes around position 2:
[17:33:08] NATURAL:8015-77-8
[17:33:08] ~^
[17:33:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
[17:33:08] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:08] SMILES Parse Error: check for mistakes around position 2:
[17:33:08] NATURAL:85409-36-9
[17:33:08] ~^
[17:33:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:33:08,332 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:33:08] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:08] SMILES Parse Error: check for mistakes around position 2:
[17:33:08] NATURAL:85409-36-9
[17:33:08] ~^
[17:33:08] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:33:08,614 INFO pino.train: Batch 286 | total=4.2418 | obj=0.2008 | season=1.2595 | wear=0.8689 | alignment=0.0007
2026-07-07 17:33:08,893 INFO pino.train: Batch 287 | total=3.8268 | obj=0.2026 | season=1.1901 | wear=0.7294 | alignment=0.0009
2026-07-07 17:33:09,164 INFO pino.train: Batch 288 | total=4.5922 | obj=0.2047 | season=1.5096 | wear=0.7873 | alignment=0.0032
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:8047-24-3
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:09,178 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:8047-24-3
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:8013-76-1
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:33:09,220 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:8013-76-1
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:7462-86-6
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:33:09,243 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:7462-86-6
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:33:09,460 INFO pino.train: Batch 289 | total=4.1334 | obj=0.1994 | season=1.2923 | wear=0.7768 | alignment=0.0026
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:8008-57-9
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:33:09,531 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:8008-57-9
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:33:09,805 INFO pino.train: Batch 290 | total=4.7539 | obj=0.2020 | season=1.5486 | wear=0.8248 | alignment=0.0030
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:7462-86-6
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:33:09,818 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:7462-86-6
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:8047-24-3
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:09,884 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:33:09] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:09] SMILES Parse Error: check for mistakes around position 2:
[17:33:09] NATURAL:8047-24-3
[17:33:09] ~^
[17:33:09] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:10,153 INFO pino.train: Batch 291 | total=3.7880 | obj=0.1950 | season=0.9821 | wear=0.9201 | alignment=0.0019
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:85409-36-9
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:33:10,202 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:85409-36-9
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8002-73-1
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:10,233 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8002-73-1
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:10,485 INFO pino.train: Batch 292 | total=4.2292 | obj=0.2065 | season=1.3607 | wear=0.7615 | alignment=0.0034
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8006-80-2
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:10,514 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8006-80-2
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8008-56-8
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:33:10,549 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8008-56-8
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:68916-26-7
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:33:10,577 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:68916-26-7
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8002-73-1
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:10,616 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8002-73-1
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:10,890 INFO pino.train: Batch 293 | total=4.0277 | obj=0.2010 | season=1.2776 | wear=0.7423 | alignment=0.0033
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8002-73-1
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:10,909 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8002-73-1
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8008-45-5
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:33:10,973 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:33:10] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:33:10] SMILES Parse Error: check for mistakes around position 2:
[17:33:10] NATURAL:8008-45-5
[17:33:10] ~^
[17:33:10] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:33:11,209 INFO pino.train: Batch 294 | total=3.7672 | obj=0.2022 | season=1.1549 | wear=0.7357 | alignment=0.0026
[17:33:11] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:11] SMILES Parse Error: check for mistakes around position 2:
[17:33:11] NATURAL:8002-73-1
[17:33:11] ~^
[17:33:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:11,265 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:11] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:11] SMILES Parse Error: check for mistakes around position 2:
[17:33:11] NATURAL:8002-73-1
[17:33:11] ~^
[17:33:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:11,539 INFO pino.train: Batch 295 | total=4.5830 | obj=0.2082 | season=1.4624 | wear=0.8352 | alignment=0.0037
[17:33:11] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:11] SMILES Parse Error: check for mistakes around position 2:
[17:33:11] NATURAL:8006-87-9
[17:33:11] ~^
[17:33:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:33:11,589 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:33:11] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:11] SMILES Parse Error: check for mistakes around position 2:
[17:33:11] NATURAL:8006-87-9
[17:33:11] ~^
[17:33:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:33:11] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:33:11] SMILES Parse Error: check for mistakes around position 2:
[17:33:11] NATURAL:8013-76-1
[17:33:11] ~^
[17:33:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:33:11,626 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:33:11] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:33:11] SMILES Parse Error: check for mistakes around position 2:
[17:33:11] NATURAL:8013-76-1
[17:33:11] ~^
[17:33:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
[17:33:11] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:11] SMILES Parse Error: check for mistakes around position 2:
[17:33:11] NATURAL:85940-31-4
[17:33:11] ~^
[17:33:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:11,671 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:33:11] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:11] SMILES Parse Error: check for mistakes around position 2:
[17:33:11] NATURAL:85940-31-4
[17:33:11] ~^
[17:33:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:11,935 INFO pino.train: Batch 296 | total=3.9528 | obj=0.2029 | season=1.1882 | wear=0.7963 | alignment=0.0040
[17:33:11] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:11] SMILES Parse Error: check for mistakes around position 2:
[17:33:11] NATURAL:85940-31-4
[17:33:11] ~^
[17:33:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:11,989 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:33:11] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:11] SMILES Parse Error: check for mistakes around position 2:
[17:33:11] NATURAL:85940-31-4
[17:33:11] ~^
[17:33:11] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:8015-61-0
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:33:12,018 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:8015-61-0
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:33:12,261 INFO pino.train: Batch 297 | total=3.9507 | obj=0.1970 | season=1.2166 | wear=0.7681 | alignment=0.0080
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:8015-77-8
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:33:12,307 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:8015-77-8
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:33:12,607 INFO pino.train: Batch 298 | total=4.2569 | obj=0.2039 | season=1.3855 | wear=0.7490 | alignment=0.0035
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:7462-86-6
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:33:12,639 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:7462-86-6
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:85409-36-9
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:33:12,680 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:85409-36-9
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:33:12,906 INFO pino.train: Batch 299 | total=3.9740 | obj=0.2015 | season=1.2065 | wear=0.7887 | alignment=0.0026
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:8032-35-1
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:33:12,925 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:8032-35-1
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:85409-36-9
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:33:12,956 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:85409-36-9
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:8032-35-1
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:33:12,990 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:33:12] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:12] SMILES Parse Error: check for mistakes around position 2:
[17:33:12] NATURAL:8032-35-1
[17:33:12] ~^
[17:33:12] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8047-24-3
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:13,033 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8047-24-3
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:13,328 INFO pino.train: Batch 300 | total=4.5221 | obj=0.2015 | season=1.4208 | wear=0.8484 | alignment=0.0019
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8002-73-1
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:13,357 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8002-73-1
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:13,599 INFO pino.train: Batch 301 | total=3.9274 | obj=0.1987 | season=1.1816 | wear=0.7915 | alignment=0.0050
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8002-73-1
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:13,633 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8002-73-1
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8047-24-3
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:13,671 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8047-24-3
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:13,933 INFO pino.train: Batch 302 | total=4.6296 | obj=0.1998 | season=1.5560 | wear=0.7601 | alignment=0.0021
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8008-57-9
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:33:13,947 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8008-57-9
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8006-81-3
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:13,981 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:33:13] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:13] SMILES Parse Error: check for mistakes around position 2:
[17:33:13] NATURAL:8006-81-3
[17:33:13] ~^
[17:33:13] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:8006-81-3
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:14,025 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:8006-81-3
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:8006-80-2
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:14,052 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:8006-80-2
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:7462-86-6
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:33:14,078 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:7462-86-6
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:89997-75-1
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:14,097 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:89997-75-1
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:8013-76-1
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:33:14,120 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:8013-76-1
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:33:14,386 INFO pino.train: Batch 303 | total=3.6084 | obj=0.2033 | season=1.0724 | wear=0.7385 | alignment=0.0068
2026-07-07 17:33:14,717 INFO pino.train: Batch 304 | total=3.5325 | obj=0.1985 | season=0.9219 | wear=0.8536 | alignment=0.0021
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:8015-77-8
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:33:14,754 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:8015-77-8
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:89997-75-1
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:14,775 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:33:14] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:14] SMILES Parse Error: check for mistakes around position 2:
[17:33:14] NATURAL:89997-75-1
[17:33:14] ~^
[17:33:14] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:15,083 INFO pino.train: Batch 305 | total=3.0516 | obj=0.2043 | season=0.7399 | wear=0.7912 | alignment=0.0017
[17:33:15] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:15] SMILES Parse Error: check for mistakes around position 2:
[17:33:15] NATURAL:8006-80-2
[17:33:15] ~^
[17:33:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:15,142 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:33:15] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:15] SMILES Parse Error: check for mistakes around position 2:
[17:33:15] NATURAL:8006-80-2
[17:33:15] ~^
[17:33:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:15,373 INFO pino.train: Batch 306 | total=3.7073 | obj=0.2008 | season=1.1323 | wear=0.7435 | alignment=0.0034
2026-07-07 17:33:15,670 INFO pino.train: Batch 307 | total=3.6525 | obj=0.2025 | season=1.1015 | wear=0.7458 | alignment=0.0015
[17:33:15] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:15] SMILES Parse Error: check for mistakes around position 2:
[17:33:15] NATURAL:85409-36-9
[17:33:15] ~^
[17:33:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:33:15,725 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:33:15] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:15] SMILES Parse Error: check for mistakes around position 2:
[17:33:15] NATURAL:85409-36-9
[17:33:15] ~^
[17:33:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:33:15,982 INFO pino.train: Batch 308 | total=4.6771 | obj=0.2079 | season=1.6213 | wear=0.7422 | alignment=0.0083
[17:33:15] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:15] SMILES Parse Error: check for mistakes around position 2:
[17:33:15] NATURAL:8032-35-1
[17:33:15] ~^
[17:33:15] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:33:15,999 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8032-35-1
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8032-35-1
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:33:16,055 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8032-35-1
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8006-87-9
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:33:16,077 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8006-87-9
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8008-31-9
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:33:16,110 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8008-31-9
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:33:16,364 INFO pino.train: Batch 309 | total=5.0061 | obj=0.1970 | season=1.7830 | wear=0.7211 | alignment=0.0034
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8032-35-1
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:33:16,441 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8032-35-1
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8008-56-8
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
2026-07-07 17:33:16,462 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-56-8
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8008-56-8
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8008-56-8
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-56-8' for input: 'NATURAL:8008-56-8'
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8002-73-1
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:16,489 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8002-73-1
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:16,744 INFO pino.train: Batch 310 | total=3.7526 | obj=0.2021 | season=1.1315 | wear=0.7517 | alignment=0.0043
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:85940-31-4
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:16,792 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:85940-31-4
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8032-35-1
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:33:16,817 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8032-35-1
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8013-76-1
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:33:16,845 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-76-1
[17:33:16] SMILES Parse Error: syntax error while parsing: NATURAL:8013-76-1
[17:33:16] SMILES Parse Error: check for mistakes around position 2:
[17:33:16] NATURAL:8013-76-1
[17:33:16] ~^
[17:33:16] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-76-1' for input: 'NATURAL:8013-76-1'
2026-07-07 17:33:17,098 INFO pino.train: Batch 311 | total=3.2413 | obj=0.2000 | season=0.8738 | wear=0.7561 | alignment=0.0057
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:8002-73-1
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:17,118 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:8002-73-1
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:8002-73-1
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:17,152 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:8002-73-1
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:17,455 INFO pino.train: Batch 312 | total=4.1043 | obj=0.1986 | season=1.1817 | wear=0.8865 | alignment=0.0039
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:89997-75-1
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:17,496 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:89997-75-1
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:8002-73-1
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:17,540 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:8002-73-1
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:17,791 INFO pino.train: Batch 313 | total=3.4423 | obj=0.2018 | season=0.9194 | wear=0.8139 | alignment=0.0024
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:8015-77-8
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
2026-07-07 17:33:17,841 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-77-8
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:8015-77-8
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:8015-77-8
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-77-8' for input: 'NATURAL:8015-77-8'
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:85940-31-4
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:17,887 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:33:17] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:17] SMILES Parse Error: check for mistakes around position 2:
[17:33:17] NATURAL:85940-31-4
[17:33:17] ~^
[17:33:17] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:18,169 INFO pino.train: Batch 314 | total=3.0536 | obj=0.2088 | season=0.6771 | wear=0.8473 | alignment=0.0040
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:7462-86-6
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:33:18,172 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:7462-86-6
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:8008-31-9
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:33:18,212 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:8008-31-9
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:8006-87-9
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:33:18,259 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:8006-87-9
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:33:18,502 INFO pino.train: Batch 315 | total=3.8797 | obj=0.2046 | season=1.1244 | wear=0.8433 | alignment=0.0040
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:7462-86-6
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:33:18,507 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:7462-86-6
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:89997-75-1
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:18,526 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:89997-75-1
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:8006-81-3
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:18,586 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:8006-81-3
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:18,876 INFO pino.train: Batch 316 | total=3.8353 | obj=0.2007 | season=1.2294 | wear=0.7259 | alignment=0.0038
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:8013-90-9
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:18,945 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:33:18] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:18] SMILES Parse Error: check for mistakes around position 2:
[17:33:18] NATURAL:8013-90-9
[17:33:18] ~^
[17:33:18] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:19,234 INFO pino.train: Batch 317 | total=3.8459 | obj=0.1991 | season=1.1761 | wear=0.7777 | alignment=0.0009
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8002-73-1
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:19,254 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8002-73-1
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8002-73-1
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:19,298 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8002-73-1
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:19,566 INFO pino.train: Batch 318 | total=4.3474 | obj=0.1971 | season=1.4793 | wear=0.7320 | alignment=0.0036
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8002-73-1
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:19,586 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8002-73-1
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8002-73-1
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:19,635 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8002-73-1
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:19,809 INFO pino.train: Batch 319 | total=3.8055 | obj=0.2087 | season=1.2223 | wear=0.7051 | alignment=0.0047
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8002-73-1
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:19,836 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8002-73-1
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8006-81-3
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:19,876 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:33:19] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:19] SMILES Parse Error: check for mistakes around position 2:
[17:33:19] NATURAL:8006-81-3
[17:33:19] ~^
[17:33:19] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:20,143 INFO pino.train: Batch 320 | total=4.3431 | obj=0.1955 | season=1.3998 | wear=0.7957 | alignment=0.0018
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:8008-57-9
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:33:20,178 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:8008-57-9
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:33:20,434 INFO pino.train: Batch 321 | total=4.6927 | obj=0.2012 | season=1.5552 | wear=0.8099 | alignment=0.0022
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:68916-26-7
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:33:20,458 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:68916-26-7
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:85940-31-4
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:20,483 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:85940-31-4
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:85940-31-4
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
2026-07-07 17:33:20,530 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85940-31-4
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:85940-31-4
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:85940-31-4
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85940-31-4' for input: 'NATURAL:85940-31-4'
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:8013-90-9
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:20,559 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:8013-90-9
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:20,783 INFO pino.train: Batch 322 | total=5.1973 | obj=0.2006 | season=1.8201 | wear=0.7775 | alignment=0.0031
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:8008-45-5
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:33:20,823 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:8008-45-5
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:8002-73-1
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:20,871 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:8002-73-1
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:8008-45-5
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:33:20,894 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:33:20] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:33:20] SMILES Parse Error: check for mistakes around position 2:
[17:33:20] NATURAL:8008-45-5
[17:33:20] ~^
[17:33:20] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:33:21,185 INFO pino.train: Batch 323 | total=3.8464 | obj=0.1941 | season=1.0652 | wear=0.8671 | alignment=0.0016
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8006-80-2
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:21,206 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8006-80-2
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:21,457 INFO pino.train: Batch 324 | total=4.3123 | obj=0.1993 | season=1.3787 | wear=0.7865 | alignment=0.0066
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8047-24-3
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:21,473 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8047-24-3
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:89997-75-1
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:21,499 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:89997-75-1
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8032-35-1
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:33:21,538 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8032-35-1
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8008-31-9
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:33:21,584 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8008-31-9
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:7462-86-6
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:33:21,599 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:7462-86-6
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:33:21,883 INFO pino.train: Batch 325 | total=4.1855 | obj=0.2019 | season=1.3384 | wear=0.7608 | alignment=0.0024
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8006-87-9
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:33:21,927 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8006-87-9
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8002-73-1
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:21,955 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:21] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:21] SMILES Parse Error: check for mistakes around position 2:
[17:33:21] NATURAL:8002-73-1
[17:33:21] ~^
[17:33:21] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:22,135 INFO pino.train: Batch 326 | total=5.3688 | obj=0.2001 | season=1.9171 | wear=0.7423 | alignment=0.0036
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:85409-36-9
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:33:22,190 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:85409-36-9
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8002-73-1
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:22,218 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8002-73-1
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:22,474 INFO pino.train: Batch 327 | total=4.8358 | obj=0.2016 | season=1.6268 | wear=0.7654 | alignment=0.0037
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8013-90-9
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:22,534 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8013-90-9
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:22,769 INFO pino.train: Batch 328 | total=4.8565 | obj=0.2012 | season=1.5826 | wear=0.8206 | alignment=0.0027
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8002-73-1
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:22,789 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8002-73-1
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8008-57-9
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:33:22,827 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8008-57-9
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8047-24-3
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
2026-07-07 17:33:22,848 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8047-24-3
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8047-24-3
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8047-24-3
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8047-24-3' for input: 'NATURAL:8047-24-3'
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8006-80-2
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:22,878 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:33:22] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:22] SMILES Parse Error: check for mistakes around position 2:
[17:33:22] NATURAL:8006-80-2
[17:33:22] ~^
[17:33:22] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:23,166 INFO pino.train: Batch 329 | total=4.4408 | obj=0.1961 | season=1.5081 | wear=0.6738 | alignment=0.0035
[17:33:23] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:23] SMILES Parse Error: check for mistakes around position 2:
[17:33:23] NATURAL:85409-36-9
[17:33:23] ~^
[17:33:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:33:23,195 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:85409-36-9
[17:33:23] SMILES Parse Error: syntax error while parsing: NATURAL:85409-36-9
[17:33:23] SMILES Parse Error: check for mistakes around position 2:
[17:33:23] NATURAL:85409-36-9
[17:33:23] ~^
[17:33:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:85409-36-9' for input: 'NATURAL:85409-36-9'
2026-07-07 17:33:23,440 INFO pino.train: Batch 330 | total=3.8367 | obj=0.1979 | season=1.2303 | wear=0.6631 | alignment=0.0018
[17:33:23] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:23] SMILES Parse Error: check for mistakes around position 2:
[17:33:23] NATURAL:8032-35-1
[17:33:23] ~^
[17:33:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
2026-07-07 17:33:23,462 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8032-35-1
[17:33:23] SMILES Parse Error: syntax error while parsing: NATURAL:8032-35-1
[17:33:23] SMILES Parse Error: check for mistakes around position 2:
[17:33:23] NATURAL:8032-35-1
[17:33:23] ~^
[17:33:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8032-35-1' for input: 'NATURAL:8032-35-1'
[17:33:23] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:23] SMILES Parse Error: check for mistakes around position 2:
[17:33:23] NATURAL:8002-73-1
[17:33:23] ~^
[17:33:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:23,508 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:23] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:23] SMILES Parse Error: check for mistakes around position 2:
[17:33:23] NATURAL:8002-73-1
[17:33:23] ~^
[17:33:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:23] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:33:23] SMILES Parse Error: check for mistakes around position 2:
[17:33:23] NATURAL:8015-61-0
[17:33:23] ~^
[17:33:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:33:23,539 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:33:23] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:33:23] SMILES Parse Error: check for mistakes around position 2:
[17:33:23] NATURAL:8015-61-0
[17:33:23] ~^
[17:33:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:33:23,746 INFO pino.train: Batch 331 | total=3.9730 | obj=0.1973 | season=1.2771 | wear=0.6831 | alignment=0.0059
[17:33:23] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:23] SMILES Parse Error: check for mistakes around position 2:
[17:33:23] NATURAL:8002-73-1
[17:33:23] ~^
[17:33:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:23,774 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:23] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:23] SMILES Parse Error: check for mistakes around position 2:
[17:33:23] NATURAL:8002-73-1
[17:33:23] ~^
[17:33:23] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:24,044 INFO pino.train: Batch 332 | total=3.8643 | obj=0.1982 | season=1.1240 | wear=0.8021 | alignment=0.0048
[17:33:24] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:33:24] SMILES Parse Error: check for mistakes around position 2:
[17:33:24] NATURAL:8015-61-0
[17:33:24] ~^
[17:33:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
2026-07-07 17:33:24,084 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8015-61-0
[17:33:24] SMILES Parse Error: syntax error while parsing: NATURAL:8015-61-0
[17:33:24] SMILES Parse Error: check for mistakes around position 2:
[17:33:24] NATURAL:8015-61-0
[17:33:24] ~^
[17:33:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8015-61-0' for input: 'NATURAL:8015-61-0'
[17:33:24] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:24] SMILES Parse Error: check for mistakes around position 2:
[17:33:24] NATURAL:8006-87-9
[17:33:24] ~^
[17:33:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:33:24,141 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-87-9
[17:33:24] SMILES Parse Error: syntax error while parsing: NATURAL:8006-87-9
[17:33:24] SMILES Parse Error: check for mistakes around position 2:
[17:33:24] NATURAL:8006-87-9
[17:33:24] ~^
[17:33:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-87-9' for input: 'NATURAL:8006-87-9'
2026-07-07 17:33:24,412 INFO pino.train: Batch 333 | total=4.2228 | obj=0.1957 | season=1.3387 | wear=0.7558 | alignment=0.0054
[17:33:24] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:24] SMILES Parse Error: check for mistakes around position 2:
[17:33:24] NATURAL:8008-57-9
[17:33:24] ~^
[17:33:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:33:24,426 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:33:24] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:24] SMILES Parse Error: check for mistakes around position 2:
[17:33:24] NATURAL:8008-57-9
[17:33:24] ~^
[17:33:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
[17:33:24] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:24] SMILES Parse Error: check for mistakes around position 2:
[17:33:24] NATURAL:68916-26-7
[17:33:24] ~^
[17:33:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:33:24,450 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:33:24] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:24] SMILES Parse Error: check for mistakes around position 2:
[17:33:24] NATURAL:68916-26-7
[17:33:24] ~^
[17:33:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:33:24] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:24] SMILES Parse Error: check for mistakes around position 2:
[17:33:24] NATURAL:7462-86-6
[17:33:24] ~^
[17:33:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:33:24,492 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:7462-86-6
[17:33:24] SMILES Parse Error: syntax error while parsing: NATURAL:7462-86-6
[17:33:24] SMILES Parse Error: check for mistakes around position 2:
[17:33:24] NATURAL:7462-86-6
[17:33:24] ~^
[17:33:24] SMILES Parse Error: Failed parsing SMILES 'NATURAL:7462-86-6' for input: 'NATURAL:7462-86-6'
2026-07-07 17:33:24,778 INFO pino.train: Batch 334 | total=4.5456 | obj=0.2006 | season=1.4548 | wear=0.7977 | alignment=0.0030
2026-07-07 17:33:25,075 INFO pino.train: Batch 335 | total=4.7162 | obj=0.1961 | season=1.5005 | wear=0.8379 | alignment=0.0076
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:89997-75-1
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:25,095 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:89997-75-1
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:8002-73-1
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:25,127 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:8002-73-1
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:8008-45-5
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:33:25,160 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-45-5
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:8008-45-5
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:8008-45-5
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-45-5' for input: 'NATURAL:8008-45-5'
2026-07-07 17:33:25,437 INFO pino.train: Batch 336 | total=3.8116 | obj=0.2018 | season=1.1665 | wear=0.7300 | alignment=0.0024
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:8008-31-9
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:33:25,452 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:8008-31-9
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:68916-26-7
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:33:25,515 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:68916-26-7
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:89997-75-1
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
2026-07-07 17:33:25,538 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:89997-75-1
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:89997-75-1
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:89997-75-1
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:89997-75-1' for input: 'NATURAL:89997-75-1'
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:8008-31-9
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:33:25,562 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:8008-31-9
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:68916-26-7
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:33:25,591 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:68916-26-7
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:68916-26-7
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:68916-26-7
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:68916-26-7' for input: 'NATURAL:68916-26-7'
2026-07-07 17:33:25,860 INFO pino.train: Batch 337 | total=3.9559 | obj=0.2033 | season=1.2184 | wear=0.7511 | alignment=0.0018
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:8008-31-9
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:33:25,898 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-31-9
[17:33:25] SMILES Parse Error: syntax error while parsing: NATURAL:8008-31-9
[17:33:25] SMILES Parse Error: check for mistakes around position 2:
[17:33:25] NATURAL:8008-31-9
[17:33:25] ~^
[17:33:25] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-31-9' for input: 'NATURAL:8008-31-9'
2026-07-07 17:33:26,101 INFO pino.train: Batch 338 | total=3.9051 | obj=0.1959 | season=1.2084 | wear=0.7369 | alignment=0.0022
[17:33:26] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:26] SMILES Parse Error: check for mistakes around position 2:
[17:33:26] NATURAL:8006-81-3
[17:33:26] ~^
[17:33:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:26,158 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-81-3
[17:33:26] SMILES Parse Error: syntax error while parsing: NATURAL:8006-81-3
[17:33:26] SMILES Parse Error: check for mistakes around position 2:
[17:33:26] NATURAL:8006-81-3
[17:33:26] ~^
[17:33:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-81-3' for input: 'NATURAL:8006-81-3'
2026-07-07 17:33:26,368 INFO pino.train: Batch 339 | total=4.0864 | obj=0.1989 | season=1.2486 | wear=0.7903 | alignment=0.0022
[17:33:26] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:26] SMILES Parse Error: check for mistakes around position 2:
[17:33:26] NATURAL:8013-90-9
[17:33:26] ~^
[17:33:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:26,394 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:33:26] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:26] SMILES Parse Error: check for mistakes around position 2:
[17:33:26] NATURAL:8013-90-9
[17:33:26] ~^
[17:33:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:26,716 INFO pino.train: Batch 340 | total=4.1603 | obj=0.2007 | season=1.2108 | wear=0.8727 | alignment=0.0037
[17:33:26] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:26] SMILES Parse Error: check for mistakes around position 2:
[17:33:26] NATURAL:8006-80-2
[17:33:26] ~^
[17:33:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:26,771 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:33:26] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:26] SMILES Parse Error: check for mistakes around position 2:
[17:33:26] NATURAL:8006-80-2
[17:33:26] ~^
[17:33:26] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:27,069 INFO pino.train: Batch 341 | total=4.4747 | obj=0.2041 | season=1.4288 | wear=0.8054 | alignment=0.0012
[17:33:27] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:27] SMILES Parse Error: check for mistakes around position 2:
[17:33:27] NATURAL:8013-90-9
[17:33:27] ~^
[17:33:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:27,093 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8013-90-9
[17:33:27] SMILES Parse Error: syntax error while parsing: NATURAL:8013-90-9
[17:33:27] SMILES Parse Error: check for mistakes around position 2:
[17:33:27] NATURAL:8013-90-9
[17:33:27] ~^
[17:33:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8013-90-9' for input: 'NATURAL:8013-90-9'
2026-07-07 17:33:27,423 INFO pino.train: Batch 342 | total=3.9798 | obj=0.2011 | season=1.1913 | wear=0.8017 | alignment=0.0028
[17:33:27] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:27] SMILES Parse Error: check for mistakes around position 2:
[17:33:27] NATURAL:8002-73-1
[17:33:27] ~^
[17:33:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:27,462 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:27] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:27] SMILES Parse Error: check for mistakes around position 2:
[17:33:27] NATURAL:8002-73-1
[17:33:27] ~^
[17:33:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:27,711 INFO pino.train: Batch 343 | total=3.7776 | obj=0.1980 | season=1.1758 | wear=0.7149 | alignment=0.0023
[17:33:27] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:27] SMILES Parse Error: check for mistakes around position 2:
[17:33:27] NATURAL:8002-73-1
[17:33:27] ~^
[17:33:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
2026-07-07 17:33:27,728 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8002-73-1
[17:33:27] SMILES Parse Error: syntax error while parsing: NATURAL:8002-73-1
[17:33:27] SMILES Parse Error: check for mistakes around position 2:
[17:33:27] NATURAL:8002-73-1
[17:33:27] ~^
[17:33:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8002-73-1' for input: 'NATURAL:8002-73-1'
[17:33:27] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:27] SMILES Parse Error: check for mistakes around position 2:
[17:33:27] NATURAL:8006-80-2
[17:33:27] ~^
[17:33:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
2026-07-07 17:33:27,752 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8006-80-2
[17:33:27] SMILES Parse Error: syntax error while parsing: NATURAL:8006-80-2
[17:33:27] SMILES Parse Error: check for mistakes around position 2:
[17:33:27] NATURAL:8006-80-2
[17:33:27] ~^
[17:33:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8006-80-2' for input: 'NATURAL:8006-80-2'
[17:33:27] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:27] SMILES Parse Error: check for mistakes around position 2:
[17:33:27] NATURAL:8008-57-9
[17:33:27] ~^
[17:33:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:33:27,776 WARNING pino.embeddings: Invalid SMILES for embedding: NATURAL:8008-57-9
[17:33:27] SMILES Parse Error: syntax error while parsing: NATURAL:8008-57-9
[17:33:27] SMILES Parse Error: check for mistakes around position 2:
[17:33:27] NATURAL:8008-57-9
[17:33:27] ~^
[17:33:27] SMILES Parse Error: Failed parsing SMILES 'NATURAL:8008-57-9' for input: 'NATURAL:8008-57-9'
2026-07-07 17:33:28,097 INFO pino.train: Batch 344 | total=4.0215 | obj=0.2000 | season=1.1992 | wear=0.8177 | alignment=0.0029