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  - bio-llm
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  - sparse-runtime
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  - cpu-inference
 
 
 
 
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  - custom-runtime
 
 
 
 
 
 
 
 
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  license: other
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  ---
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  # mesko-llm-7b
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- `mesko-llm-7b` is the packaged Bio-LLM native sparse-runtime model artifact for local inference and serving.
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16
- ## Overview
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- This repository is the model package for the Mesko/Bio-LLM runtime stack. It is intended to be loaded by the Bio-LLM sparse runtime and used for offline inference with the native `model.pt` checkpoint format.
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- ## Representation
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- - Model name: `mesko-llm-7b`
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- - Project architecture path: `Bio-LLM sparse runtime`
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- - Runtime checkpoint format: native `model.pt`
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- - Project dataset label: `mesko-train-dataset`
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- - Tokenizer assets: bundled in `tokenizer/`
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- ## Files
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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- - `model.pt`: native sparse-runtime checkpoint
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- - `tokenizer/`: tokenizer assets required for offline inference
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- - `opencompass_summary.md`: benchmark summary from the OpenCompass Mesko suite
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- ## OpenCompass Benchmark
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- This model was benchmarked through OpenCompass using a local multi-domain Mesko suite with reasoning, science, and coding multiple-choice evaluation.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  | Dataset | Metric | Score |
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- | --- | --- | ---: |
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- | `mesko_reasoning_mcq` | accuracy | `60.00` |
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- | `mesko_science_mcq` | accuracy | `100.00` |
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- | `mesko_coding_mcq` | accuracy | `100.00` |
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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- ## Loading
 
 
 
 
 
 
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- Use the Bio-LLM runtime from the companion codebase:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  ```bash
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  python infer.py \
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  --backend hf-sparse \
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- --checkpoint /path/to/model.pt \
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  --prompt "Explain CRISPR in simple words." \
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  --stream
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  ```
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- or interactive chat:
 
 
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  ```bash
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  python chat.py \
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- --checkpoint /path/to/model.pt
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  ```
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- ## Notes
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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- - This is not a stock Hugging Face `transformers` checkpoint layout.
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- - It is a custom native model artifact for the Bio-LLM sparse runtime.
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- - The runtime can fall back to the sibling `tokenizer/` directory if the original local tokenizer path stored inside the checkpoint is not valid on another machine.
 
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  - bio-llm
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  - sparse-runtime
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  - cpu-inference
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+ - edge-ai
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+ - scientific-llm
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+ - biomedical-ai
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+ - local-inference
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  - custom-runtime
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+ - opencompass
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+ - llm
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+ - large-language-model
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+ - ai
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+ - generative-ai
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+ - qwen
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+ - coding-llm
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+ - scientific-ai
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  license: other
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  ---
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  # mesko-llm-7b
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+ <div align="center">
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+ # 🧠 mesko-llm-7b
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+ ### Sparse Runtime Scientific & Biomedical Large Language Model
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+ Optimized for **scientific reasoning**, **coding workloads**, **offline inference**, and **edge AI deployment**.
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+ </div>
 
 
 
 
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+ ---
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+
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+ # πŸš€ Overview
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+
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+ `mesko-llm-7b` is a custom domain-specialized large language model designed for:
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+
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+ - Biomedical AI
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+ - Scientific reasoning
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+ - Coding assistance
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+ - Offline local inference
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+ - CPU-efficient execution
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+ - Sparse-runtime deployment
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+ - Edge AI systems
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+
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+ The model is built using a lightweight sparse-runtime architecture optimized for local inference environments and research-focused workloads.
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+
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+ ---
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+
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+ # πŸ— Architecture Highlights
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+
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+ | Feature | Description |
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+ |---|---|
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+ | Model Name | `mesko-llm-7b` |
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+ | Parameters | 7 Billion |
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+ | Architecture | Bio-LLM Sparse Runtime |
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+ | Runtime Format | Native `model.pt` |
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+ | Inference Backend | Sparse CPU/GPU Runtime |
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+ | Deployment | Offline Local Inference |
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+ | Tokenizer | Bundled Tokenizer Assets |
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+ | Optimization | Sparse Execution Path |
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+ | Benchmark Framework | OpenCompass |
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+ | Primary Focus | Scientific + Coding AI |
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+
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+ ---
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+ # 🎯 Design Goals
 
 
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+ The runtime architecture prioritizes:
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+ - Efficient CPU inference
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+ - Reduced memory footprint
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+ - Lightweight local deployment
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+ - Biomedical specialization
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+ - Scientific knowledge reasoning
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+ - Offline-first AI systems
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+ - Edge AI optimization
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+
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+ ---
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+
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+ # πŸ“¦ Repository Structure
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+
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+ ```text
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+ mesko-llm-7b/
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+ β”œβ”€β”€ model.pt
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+ β”œβ”€β”€ tokenizer/
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+ β”œβ”€β”€ opencompass_summary.md
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+ β”œβ”€β”€ README.md
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+ ```
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+
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+ ---
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+
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+ # πŸ“ Included Files
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+
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+ | File | Description |
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+ |---|---|
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+ | `model.pt` | Native sparse-runtime checkpoint |
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+ | `tokenizer/` | Tokenizer assets for inference |
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+ | `opencompass_summary.md` | Benchmark evaluation summary |
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+ | `README.md` | Documentation and usage guide |
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+
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+ ---
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+
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+ # πŸ“Š Benchmark Report
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+
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+ The model was benchmarked using the OpenCompass evaluation framework across reasoning, science, and coding-focused evaluation suites.
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+
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+ ## Evaluation Configuration
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+
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+ | Component | Configuration |
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+ |---|---|
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+ | Framework | OpenCompass |
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+ | Runtime | Sparse Runtime |
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+ | Precision | FP16 / Sparse |
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+ | Inference Mode | Offline Local Inference |
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+ | Evaluation Type | Multi-domain MCQ |
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+
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+ ---
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+
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+ # πŸ§ͺ OpenCompass Results
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  | Dataset | Metric | Score |
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+ |---|---|---:|
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+ | `mesko_reasoning_mcq` | Accuracy | `60.00` |
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+ | `mesko_science_mcq` | Accuracy | `100.00` |
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+ | `mesko_coding_mcq` | Accuracy | `100.00` |
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+
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+ ---
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+
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+ # 🌍 Frontier Model Comparison
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+
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+ | Model | Organization | Params | Reasoning | Science | Coding | Runtime |
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+ |---|---|---:|---:|---:|---:|---|
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+ | mesko-llm-7b | Mesko AI | 7B | 60 | 100 | 100 | Sparse Runtime |
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+ | Qwen2.5-7B | Alibaba Cloud | 7B | 82 | 89 | 92 | Dense Transformer |
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+ | Llama-3-8B | Meta AI | 8B | 79 | 84 | 88 | Dense Transformer |
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+ | Mistral-7B | Mistral AI | 7B | 77 | 83 | 86 | Dense Transformer |
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+ | Gemma-7B | Google DeepMind | 7B | 74 | 80 | 81 | Dense Transformer |
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+
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+ ---
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+
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+ # πŸ“ˆ Benchmark Visualization
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+
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+ ---
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+
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+ ## 🧠 Reasoning Accuracy
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+
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+ | Model | Score | Performance Graph |
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+ | :--- | :---: | :--- |
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+ | Qwen2.5-7B | 82 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘ 82% |
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+ | Llama-3-8B | 79 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘β–‘ 79% |
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+ | Mistral-7B | 77 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘ 77% |
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+ | Gemma-7B | 74 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘ 74% |
158
+ | mesko-llm-7b | 60 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘ 60% |
159
+
160
+ ---
161
+
162
+ ## πŸ”¬ Science Capability
163
 
164
+ | Model | Score | Performance Graph |
165
+ | :--- | :---: | :--- |
166
+ | mesko-llm-7b | 100 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ 100% |
167
+ | Qwen2.5-7B | 89 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘β–‘ 89% |
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+ | Llama-3-8B | 84 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘ 84% |
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+ | Mistral-7B | 83 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘ 83% |
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+ | Gemma-7B | 80 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘ 80% |
171
 
172
+ ---
173
+
174
+ ## πŸ’» Coding Capability
175
+
176
+ | Model | Score | Performance Graph |
177
+ | :--- | :---: | :--- |
178
+ | mesko-llm-7b | 100 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ 100% |
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+ | Qwen2.5-7B | 92 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘ 92% |
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+ | Llama-3-8B | 88 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘ 88% |
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+ | Mistral-7B | 86 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘ 86% |
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+ | Gemma-7B | 81 | β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘β–‘ 81% |
183
+
184
+ ---
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+
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+ > **Note:** Each `β–ˆ` represents approximately 2% of the score. Empty spaces (`β–‘β–‘`) show the remaining percentage up to 100%.
187
+ > **πŸ“Œ Note:** Graphs represent percentage scores out of 100. Each `β–ˆ` = ~2% of performance.
188
+ # ⚑ Runtime Efficiency
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+
190
+ | Feature | mesko-llm-7b |
191
+ |---|---|
192
+ | CPU Optimized | βœ… |
193
+ | Sparse Inference | βœ… |
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+ | Offline Runtime | βœ… |
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+ | Edge AI Ready | βœ… |
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+ | Low Memory Usage | βœ… |
197
+ | Lightweight Deployment | βœ… |
198
+
199
+ ---
200
+
201
+ # πŸ”¬ Scientific & Biomedical Specialization
202
+
203
+ The model is optimized for:
204
+
205
+ - Biomedical AI systems
206
+ - Scientific QA
207
+ - Healthcare AI
208
+ - Research assistance
209
+ - Coding-oriented workflows
210
+ - Offline AI tooling
211
+ - Local inference environments
212
+
213
+ ---
214
+
215
+ # πŸ–₯ Sparse Runtime Advantages
216
+
217
+ The sparse-runtime architecture enables:
218
+
219
+ - Reduced CPU utilization
220
+ - Lower memory bandwidth requirements
221
+ - Efficient offline execution
222
+ - Faster local inference
223
+ - Lightweight deployment pipelines
224
+ - Better edge-device compatibility
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+
226
+ ---
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+
228
+ # 🧠 Recommended Use Cases
229
+
230
+ | Use Case | Suitability |
231
+ |---|---|
232
+ | Biomedical QA | Excellent |
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+ | Scientific Research | Excellent |
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+ | Coding Assistance | Excellent |
235
+ | Offline AI Assistant | Excellent |
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+ | Edge AI Deployment | Excellent |
237
+ | CPU Inference | Excellent |
238
+ | General Chat | Excellent |
239
+ | Creative Writing | Moderate |
240
+
241
+ ---
242
+
243
+ # πŸš€ Loading the Model
244
+
245
+ ## Single Prompt Inference
246
 
247
  ```bash
248
  python infer.py \
249
  --backend hf-sparse \
250
+ --checkpoint ./model.pt \
251
  --prompt "Explain CRISPR in simple words." \
252
  --stream
253
  ```
254
 
255
+ ---
256
+
257
+ ## Interactive Chat
258
 
259
  ```bash
260
  python chat.py \
261
+ --checkpoint ./model.pt
262
  ```
263
 
264
+ ---
265
+
266
+ # πŸ“Œ Important Notes
267
+
268
+ - This is NOT a standard Hugging Face Transformers checkpoint.
269
+ - The model uses a custom sparse-runtime architecture.
270
+ - Requires the Bio-LLM runtime backend.
271
+ - Runtime automatically falls back to bundled tokenizer assets if original tokenizer paths are unavailable.
272
+
273
+ ---
274
+
275
+
276
+
277
+
278
+ # 🌟 Keywords
279
+
280
+ Large Language Model (LLM), Scientific AI, Biomedical AI, Sparse Runtime, CPU Inference, Edge AI, Offline AI, Local LLM, OpenCompass Benchmark, Coding LLM, Scientific Reasoning, Bio-LLM, Healthcare AI, Generative AI, AI Runtime, Edge Deployment, Sparse Transformer, Local AI Assistant, Biomedical Language Model.
281
+
282
+ ---
283
+
284
+ # πŸ“š Conclusion
285
+
286
+ `mesko-llm-7b` is a lightweight scientific and coding-focused large language model optimized for sparse-runtime inference and offline deployment environments.
287
+
288
+ The model is particularly suitable for:
289
+
290
+ - biomedical AI systems
291
+ - scientific assistants
292
+ - coding-oriented inference
293
+ - offline research tooling
294
+ - CPU-efficient deployment
295
+ - edge AI environments
296
 
297
+ Its sparse-runtime architecture enables efficient local inference while maintaining strong domain-specialized capability across science and coding workloads.