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language:
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- en
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tags:
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- genomics
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- Hi-C
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- foundation-model
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- chromosome-conformation-capture
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---
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language:
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- en
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tags:
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- arch3d
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- genomics
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- Hi-C
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- foundation-model
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- genome-architecture
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- global-genome-architecture
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- chromosome-conformation-capture
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---
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# ARCH3D: A foundation model for global genome architecture
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This repository contains the checkpoints
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- `pretrained.ckpt`: Pre-trained ARCHED with the pre-training task head
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- `enhanced.ckpt`: ARCH3D fine-tuned for resolution enhancement
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- `hyperedge.ckpt`: ARCH3D with a task head for predicting hyperedges
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If you use this model in your work, please cite:
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Galioto, Nicholas, et al. "ARCH3D: A foundation model for global genome architecture." _bioRxiv_ (2026): 2026-02.
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```bibtex
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@article{galioto2026arch3d,
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title={{ARCH3D}: A foundation model for global genome architecture},
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author={Galioto, Nicholas and Stansbury, Cooper and Gorodetsky, Alex Arkady and Rajapakse, Indika},
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journal={bioRxiv},
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pages={2026--02},
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year={2026},
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publisher={Cold Spring Harbor Laboratory}
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}
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```
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