{
  "source": "RosettaCommons/RFdiffusion",
  "checkpoint_variant": "Complex_base_ckpt",
  "model": {
    "num_extra_blocks": 4,
    "num_main_blocks": 32,
    "num_refinement_blocks": 4,
    "msa_size": 256,
    "full_msa_size": 64,
    "pair_size": 128,
    "template_size": 64,
    "num_msa_attention_heads": 8,
    "num_pair_attention_heads": 4,
    "num_template_attention_heads": 4,
    "hidden_size": 32,
    "template_hidden_size": 32,
    "dropout": 0.15,
    "time_embedding_size": 0,
    "time_embedding_projection_size": 10,
    "freeze_track_motif": false,
    "use_motif_timestep": true,
    "se3_param_full": {
      "num_layers": 1,
      "num_channels": 32,
      "num_degrees": 2,
      "num_attention_heads": 4,
      "div": 4,
      "l0_in_features": 8,
      "l0_out_features": 8,
      "l1_in_features": 3,
      "l1_out_features": 2,
      "num_edge_features": 32
    },
    "se3_param_topk": {
      "num_layers": 1,
      "num_channels": 32,
      "num_degrees": 2,
      "num_attention_heads": 4,
      "div": 4,
      "l0_in_features": 64,
      "l0_out_features": 64,
      "l1_in_features": 3,
      "l1_out_features": 2,
      "num_edge_features": 64
    },
    "vocab_size": 21
  },
  "diffuser": {
    "num_timesteps": 50,
    "b_0": 0.01,
    "b_T": 0.07,
    "min_b": 1.5,
    "max_b": 2.5,
    "min_sigma": 0.02,
    "max_sigma": 1.5,
    "schedule_type": "linear",
    "so3_schedule_type": "linear",
    "so3_type": "igso3",
    "crd_scale": 0.25,
    "partial_timesteps": null,
    "truncation_level": 2000,
    "igso3_num_omega": 1000,
    "igso3_num_sigma": 500
  },
  "preprocess": {
    "sidechain_input": false,
    "motif_sidechain_input": true,
    "template_1d_size": 24,
    "template_2d_size": 44,
    "predict_previous": false,
    "prob_self_cond": 0.5,
    "str_self_cond": true
  },
  "denoiser": {
    "noise_scale_ca": 1.0,
    "final_noise_scale_ca": 1.0,
    "ca_noise_schedule_type": "constant",
    "noise_scale_frame": 1.0,
    "final_noise_scale_frame": 1.0,
    "frame_noise_schedule_type": "constant"
  },
  "inference": {
    "input_pdb": null,
    "num_designs": 1,
    "design_startnum": 0,
    "ckpt_override_path": null,
    "symmetry": null,
    "recenter": true,
    "radius": 10.0,
    "model_only_neighbors": false,
    "output_prefix": "samples/design",
    "write_trajectory": false,
    "empty_cache_per_design": false,
    "scaffold_guided": false,
    "model_runner": "SelfConditioning",
    "cautious": true,
    "align_motif": true,
    "symmetric_self_cond": true,
    "final_step": 1,
    "deterministic": false,
    "trb_save_ckpt_path": null,
    "schedule_directory_path": null,
    "model_directory_path": null,
    "cyclic": false,
    "cyc_chains": "a"
  },
  "contigmap": {
    "contigs": null,
    "inpaint_seq": null,
    "inpaint_str": null,
    "inpaint_str_helix": null,
    "inpaint_str_strand": null,
    "inpaint_str_loop": null,
    "provide_seq": null,
    "length": null
  },
  "ppi": {
    "hotspot_res": null
  },
  "potentials": {
    "guiding_potentials": null,
    "guide_scale": 10.0,
    "guide_decay": "constant",
    "olig_inter_all": null,
    "olig_intra_all": null,
    "olig_custom_contact": null,
    "substrate": null
  },
  "scaffoldguided": {
    "scaffoldguided": false,
    "target_pdb": false,
    "target_path": null,
    "scaffold_list": null,
    "scaffold_dir": null,
    "sampled_insertion": 0,
    "sampled_N": 0,
    "sampled_C": 0,
    "ss_mask": 0,
    "systematic": false,
    "target_ss": null,
    "target_adj": null,
    "mask_loops": true,
    "contig_crop": null
  },
  "logging": {
    "inputs": false
  }
}