MMedAgent-Plus: Scaling Multimodal Medical Agents across Modalities, Tasks and Workflows
Abstract
MMedAgent-Plus is a multimodal medical agent that coordinates specialist AI models via a vision-language planner to execute multi-step clinical analyses with high accuracy and faithful synthesis.
Medical workflows often require multiple interdependent analyses, but existing specialist and generalist AI models are not designed to coordinate them. We introduce MMedAgent-Plus, a multimodal medical tool-use agent that combines a vision-language planner with 18 leading specialist models spanning 12 tasks and 8 modalities. Through a unified tool interface, the planner selects specialists, executes them in sequence, and synthesizes responses grounded in their outputs. The planner is instruction-tuned on 208,928 samples from 32 public medical benchmarks, covering single- and multi-tool interactions across single and multiple rounds. We separately evaluate tool orchestration, response synthesis, and end-to-end execution on held-out samples. MMedAgent-Plus achieves tool-call accuracies of 91.0%, 98.1%, and 80.7% in single-tool multi-round, multi-tool multi-round, and multi-tool single-round settings, respectively. Given correct tool outputs, MMedAgent-Plus achieves scores of 14.4-14.8 out of 15 for faithfulness, completeness, and conciseness across 600 evaluation samples. In end-to-end execution without pre-supplied tool outputs, MMedAgent-Plus correctly invokes the required specialist in 90.6% of 350 evaluation cases spanning seven tasks. Its final-answer accuracy reaches 0.98, matching the dedicated leading specialist and exceeding the strongest baseline (0.28).
Community
Medical AI has made remarkable progress, with specialist models achieving impressive performance across individual tasks. But real-world medical workflows rarely involve just one task. They often require multiple analyses, specialized expertise, and the ability to connect intermediate findings.
In MMedAgent-Plus, we address this challenge by developing a multimodal medical agent that learns to select, invoke, and coordinate specialist models across diverse medical workflows.
๐ Key highlights:
๐น Broad specialist coverage: We integrate 18 specialist models spanning 12 medical tasks and 8 modalities, including CT, MRI, X-ray, ultrasound, retinal fundus imaging, retinal OCT, and pathology.
๐น Learning tool orchestration: We curate 208K+ instruction-tuning samples from 32 public medical benchmarks, covering single-tool, multi-tool, and multi-round interactions.
๐น Tool-grounded responses: Given correct specialist outputs, final responses score 14.4โ14.8/15 on faithfulness, completeness, and conciseness, outperforming GPT-5.4-mini, Qwen3-VL, MedGemma, and LLaVA-Med.
๐น Reliable end-to-end results: MMedAgent-Plus invokes the correct specialist in 90.6% of evaluated cases and matches specialist-level accuracy on medical QA (0.98 vs. 0.28 for the strongest direct-answer baseline).
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