popV version: 0.6.0

.gitattributes

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+harmony_knn_classifier.index filter=lfs diff=lfs merge=lfs -text
+scvi_knn_classifier.index filter=lfs diff=lfs merge=lfs -text

OnClass.data-00000-of-00001

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OnClass.npz

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README.md

@@ -1,74 +0,0 @@
----
-library_name: popV
-license: cc-by-4.0
-tags:
-- biology
-- genomics
-- single-cell
-- anndata_version:0.11.3
-- python_version:3.11.11
-- popV
-- 'tissue: Prostate'
----
-
-Popular Vote (popV) model for automated cell type annotation of single-cell RNA-seq data. We provide here pretrained models
-for plug-in use in your own analysis.
-Follow our [tutorial](https://github.com/YosefLab/popV/blob/main/tabula_sapiens_tutorial.ipynb) to learn how to use the model for cell type annotation.
-
-# Model description
-
-Tabula Sapiens is a benchmark, first-draft human cell atlas of over 1.1M cells from 28 organs of 24 normal human subjects. This work is the product of the Tabula Sapiens Consortium. Taking the organs from the same individual controls for genetic background, age, environment, and epigenetic effects, and allows detailed analysis and comparison of cell types that are shared between tissues.
-
-**Link to CELLxGENE**:
-Link to the [data](https://cellxgene.cziscience.com/e/d77ec7d6-ef2e-49d6-9e79-05b7f8881484.cxg/) in the CELLxGENE browser for interactive exploration of the data and download of the source data.
-
-**Training Code URL**:
-Not provided by uploader.
-
-# Metrics
-
-We provide here accuracies for each of the experts and the ensemble model. The validation set accuracies are
-computed on a 10% random subset of the data that was not used for training.
-
-| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |
-| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
-| luminal cell of prostate epithelium | 1055 | 0.94 | 0.96 | 0.97 | 0.94 | 0.00 | 0.92 | 0.95 | 0.94 | 0.96 |
-| basal cell of prostate epithelium | 348 | 0.85 | 0.88 | 0.90 | 0.83 | 0.00 | 0.82 | 0.87 | 0.86 | 0.89 |
-| CD8-positive, alpha-beta T cell | 255 | 0.91 | 0.88 | 0.95 | 0.87 | 0.00 | 0.92 | 0.92 | 0.93 | 0.95 |
-| endothelial cell | 127 | 0.98 | 0.98 | 0.99 | 0.96 | 0.00 | 0.96 | 0.98 | 0.98 | 0.98 |
-| macrophage | 94 | 0.96 | 0.98 | 0.98 | 0.97 | 0.00 | 0.99 | 0.99 | 0.96 | 0.98 |
-| fibroblast | 58 | 0.96 | 0.95 | 0.97 | 0.83 | 0.00 | 0.96 | 0.97 | 0.95 | 0.98 |
-| mature NK T cell | 50 | 0.91 | 0.18 | 0.92 | 0.12 | 0.00 | 0.90 | 0.91 | 0.92 | 0.93 |
-| smooth muscle cell | 46 | 0.94 | 0.94 | 0.93 | 0.80 | 0.00 | 0.86 | 0.93 | 0.88 | 0.94 |
-| neutrophil | 23 | 0.98 | 1.00 | 1.00 | 0.96 | 0.00 | 0.96 | 1.00 | 1.00 | 1.00 |
-| erythrocyte | 20 | 0.90 | 0.86 | 0.95 | 0.95 | 0.00 | 0.88 | 0.97 | 0.97 | 0.97 |
-| CD4-positive, alpha-beta T cell | 14 | 0.17 | 0.00 | 0.00 | 0.00 | 0.00 | 0.49 | 0.50 | 0.34 | 0.19 |
-| B cell | 8 | 0.75 | 0.77 | 0.80 | 0.71 | 0.00 | 0.89 | 0.88 | 0.80 | 0.80 |
-| mast cell | 4 | 1.00 | 0.73 | 1.00 | 0.29 | 0.00 | 0.50 | 1.00 | 1.00 | 1.00 |
-| T cell | 1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
-
-The train accuracies are computed on the training data.
-
-| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |
-| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
-| luminal cell of prostate epithelium | 9597 | 0.95 | 0.96 | 0.98 | 0.96 | 0.00 | 0.93 | 0.96 | 0.95 | 0.97 |
-| basal cell of prostate epithelium | 3147 | 0.87 | 0.88 | 0.94 | 0.90 | 0.00 | 0.84 | 0.89 | 0.88 | 0.91 |
-| CD8-positive, alpha-beta T cell | 2261 | 0.93 | 0.89 | 0.96 | 0.91 | 0.00 | 0.94 | 0.94 | 0.95 | 0.96 |
-| endothelial cell | 1078 | 0.98 | 0.96 | 0.98 | 0.94 | 0.00 | 0.97 | 0.97 | 0.97 | 0.99 |
-| macrophage | 928 | 0.98 | 0.98 | 0.98 | 0.97 | 0.00 | 0.99 | 1.00 | 0.99 | 1.00 |
-| fibroblast | 461 | 0.96 | 0.95 | 0.98 | 0.86 | 0.00 | 0.95 | 0.98 | 0.97 | 0.99 |
-| mature NK T cell | 437 | 0.91 | 0.17 | 0.91 | 0.54 | 0.00 | 0.89 | 0.92 | 0.93 | 0.94 |
-| smooth muscle cell | 431 | 0.95 | 0.92 | 0.97 | 0.81 | 0.00 | 0.93 | 0.97 | 0.96 | 0.99 |
-| neutrophil | 238 | 0.99 | 0.98 | 0.99 | 0.96 | 0.00 | 0.99 | 1.00 | 1.00 | 0.99 |
-| erythrocyte | 119 | 0.93 | 0.85 | 0.97 | 0.92 | 0.00 | 0.90 | 0.99 | 0.98 | 0.98 |
-| CD4-positive, alpha-beta T cell | 102 | 0.31 | 0.00 | 0.19 | 0.13 | 0.00 | 0.65 | 0.64 | 0.65 | 0.47 |
-| B cell | 93 | 0.82 | 0.81 | 0.84 | 0.82 | 0.00 | 0.92 | 0.96 | 0.96 | 0.96 |
-| mast cell | 22 | 1.00 | 0.65 | 1.00 | 0.69 | 0.00 | 0.70 | 0.98 | 0.98 | 0.98 |
-| T cell | 13 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.51 | 0.93 | 0.70 | 0.92 |
-
-</details>
-
-
-# References
-
-Tabula Sapiens reveals transcription factor expression, senescence effects, and sex-specific features in cell types from 28 human organs and tissues, The Tabula Sapiens Consortium; bioRxiv, doi: https://doi.org/10.1101/2024.12.03.626516

accuracies.json

@@ -1,4 +1,4 @@
 {
-    "query_accuracy": "| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |\n| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |\n| luminal cell of prostate epithelium | 1055 | 0.94 | 0.96 | 0.97 | 0.94 | 0.00 | 0.92 | 0.95 | 0.94 | 0.96 |\n| basal cell of prostate epithelium | 348 | 0.85 | 0.88 | 0.90 | 0.83 | 0.00 | 0.82 | 0.87 | 0.86 | 0.89 |\n| CD8-positive, alpha-beta T cell | 255 | 0.91 | 0.88 | 0.95 | 0.87 | 0.00 | 0.92 | 0.92 | 0.93 | 0.95 |\n| endothelial cell | 127 | 0.98 | 0.98 | 0.99 | 0.96 | 0.00 | 0.96 | 0.98 | 0.98 | 0.98 |\n| macrophage | 94 | 0.96 | 0.98 | 0.98 | 0.97 | 0.00 | 0.99 | 0.99 | 0.96 | 0.98 |\n| fibroblast | 58 | 0.96 | 0.95 | 0.97 | 0.83 | 0.00 | 0.96 | 0.97 | 0.95 | 0.98 |\n| mature NK T cell | 50 | 0.91 | 0.18 | 0.92 | 0.12 | 0.00 | 0.90 | 0.91 | 0.92 | 0.93 |\n| smooth muscle cell | 46 | 0.94 | 0.94 | 0.93 | 0.80 | 0.00 | 0.86 | 0.93 | 0.88 | 0.94 |\n| neutrophil | 23 | 0.98 | 1.00 | 1.00 | 0.96 | 0.00 | 0.96 | 1.00 | 1.00 | 1.00 |\n| erythrocyte | 20 | 0.90 | 0.86 | 0.95 | 0.95 | 0.00 | 0.88 | 0.97 | 0.97 | 0.97 |\n| CD4-positive, alpha-beta T cell | 14 | 0.17 | 0.00 | 0.00 | 0.00 | 0.00 | 0.49 | 0.50 | 0.34 | 0.19 |\n| B cell | 8 | 0.75 | 0.77 | 0.80 | 0.71 | 0.00 | 0.89 | 0.88 | 0.80 | 0.80 |\n| mast cell | 4 | 1.00 | 0.73 | 1.00 | 0.29 | 0.00 | 0.50 | 1.00 | 1.00 | 1.00 |\n| T cell | 1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |",
-    "ref_accuracy": "| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |\n| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |\n| luminal cell of prostate epithelium | 9597 | 0.95 | 0.96 | 0.98 | 0.96 | 0.00 | 0.93 | 0.96 | 0.95 | 0.97 |\n| basal cell of prostate epithelium | 3147 | 0.87 | 0.88 | 0.94 | 0.90 | 0.00 | 0.84 | 0.89 | 0.88 | 0.91 |\n| CD8-positive, alpha-beta T cell | 2261 | 0.93 | 0.89 | 0.96 | 0.91 | 0.00 | 0.94 | 0.94 | 0.95 | 0.96 |\n| endothelial cell | 1078 | 0.98 | 0.96 | 0.98 | 0.94 | 0.00 | 0.97 | 0.97 | 0.97 | 0.99 |\n| macrophage | 928 | 0.98 | 0.98 | 0.98 | 0.97 | 0.00 | 0.99 | 1.00 | 0.99 | 1.00 |\n| fibroblast | 461 | 0.96 | 0.95 | 0.98 | 0.86 | 0.00 | 0.95 | 0.98 | 0.97 | 0.99 |\n| mature NK T cell | 437 | 0.91 | 0.17 | 0.91 | 0.54 | 0.00 | 0.89 | 0.92 | 0.93 | 0.94 |\n| smooth muscle cell | 431 | 0.95 | 0.92 | 0.97 | 0.81 | 0.00 | 0.93 | 0.97 | 0.96 | 0.99 |\n| neutrophil | 238 | 0.99 | 0.98 | 0.99 | 0.96 | 0.00 | 0.99 | 1.00 | 1.00 | 0.99 |\n| erythrocyte | 119 | 0.93 | 0.85 | 0.97 | 0.92 | 0.00 | 0.90 | 0.99 | 0.98 | 0.98 |\n| CD4-positive, alpha-beta T cell | 102 | 0.31 | 0.00 | 0.19 | 0.13 | 0.00 | 0.65 | 0.64 | 0.65 | 0.47 |\n| B cell | 93 | 0.82 | 0.81 | 0.84 | 0.82 | 0.00 | 0.92 | 0.96 | 0.96 | 0.96 |\n| mast cell | 22 | 1.00 | 0.65 | 1.00 | 0.69 | 0.00 | 0.70 | 0.98 | 0.98 | 0.98 |\n| T cell | 13 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.51 | 0.93 | 0.70 | 0.92 |"
+    "query_accuracy": "| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |\n| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |\n| luminal cell of prostate epithelium | 1072 | 0.95 | 0.96 | 0.97 | 0.96 | 0.00 | 0.92 | 0.95 | 0.95 | 0.96 |\n| basal cell of prostate epithelium | 340 | 0.86 | 0.87 | 0.90 | 0.88 | 0.00 | 0.84 | 0.87 | 0.86 | 0.89 |\n| CD8-positive, alpha-beta T cell | 246 | 0.95 | 0.89 | 0.95 | 0.91 | 0.00 | 0.92 | 0.91 | 0.94 | 0.95 |\n| endothelial cell | 126 | 0.98 | 0.98 | 0.97 | 0.98 | 0.00 | 0.98 | 0.96 | 0.96 | 0.98 |\n| macrophage | 93 | 0.97 | 0.98 | 0.98 | 0.98 | 0.00 | 0.96 | 0.98 | 0.96 | 0.98 |\n| fibroblast | 58 | 0.97 | 0.96 | 0.97 | 0.96 | 0.00 | 0.88 | 0.97 | 0.95 | 0.98 |\n| mature NK T cell | 46 | 0.93 | 0.12 | 0.92 | 0.68 | 0.00 | 0.94 | 0.88 | 0.94 | 0.92 |\n| smooth muscle cell | 50 | 0.94 | 0.95 | 0.91 | 0.91 | 0.00 | 0.83 | 0.96 | 0.88 | 0.95 |\n| neutrophil | 23 | 0.98 | 0.98 | 0.98 | 1.00 | 0.00 | 0.96 | 1.00 | 0.98 | 0.98 |\n| erythrocyte | 21 | 0.91 | 0.87 | 0.93 | 0.93 | 0.00 | 0.93 | 0.98 | 1.00 | 0.98 |\n| CD4-positive, alpha-beta T cell | 13 | 0.12 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.39 | 0.48 | 0.14 |\n| B cell | 10 | 0.84 | 0.89 | 0.84 | 0.76 | 0.00 | 0.80 | 0.90 | 0.90 | 0.84 |\n| mast cell | 4 | 1.00 | 1.00 | 0.86 | 0.67 | 0.00 | 0.40 | 1.00 | 1.00 | 1.00 |\n| T cell | 1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |",
+    "ref_accuracy": "| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |\n| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |\n| luminal cell of prostate epithelium | 9580 | 0.95 | 0.97 | 0.97 | 0.96 | 0.00 | 0.94 | 0.96 | 0.95 | 0.97 |\n| basal cell of prostate epithelium | 3155 | 0.87 | 0.91 | 0.93 | 0.91 | 0.00 | 0.88 | 0.89 | 0.88 | 0.92 |\n| CD8-positive, alpha-beta T cell | 2270 | 0.95 | 0.89 | 0.95 | 0.93 | 0.00 | 0.94 | 0.95 | 0.96 | 0.96 |\n| endothelial cell | 1079 | 0.97 | 0.97 | 0.98 | 0.97 | 0.00 | 0.98 | 0.97 | 0.96 | 0.98 |\n| macrophage | 929 | 0.98 | 0.98 | 0.98 | 0.97 | 0.00 | 0.98 | 1.00 | 0.99 | 0.99 |\n| fibroblast | 461 | 0.96 | 0.96 | 0.97 | 0.94 | 0.00 | 0.87 | 0.98 | 0.96 | 0.98 |\n| mature NK T cell | 441 | 0.91 | 0.18 | 0.90 | 0.79 | 0.00 | 0.91 | 0.92 | 0.93 | 0.94 |\n| smooth muscle cell | 427 | 0.95 | 0.94 | 0.95 | 0.93 | 0.00 | 0.83 | 0.98 | 0.97 | 0.98 |\n| neutrophil | 238 | 0.98 | 0.99 | 0.99 | 0.99 | 0.00 | 0.96 | 1.00 | 0.99 | 0.99 |\n| erythrocyte | 118 | 0.95 | 0.86 | 0.95 | 0.93 | 0.00 | 0.86 | 0.99 | 0.99 | 0.98 |\n| CD4-positive, alpha-beta T cell | 103 | 0.28 | 0.00 | 0.00 | 0.00 | 0.00 | 0.49 | 0.70 | 0.73 | 0.33 |\n| B cell | 91 | 0.82 | 0.84 | 0.83 | 0.83 | 0.00 | 0.94 | 0.98 | 0.96 | 0.97 |\n| mast cell | 22 | 1.00 | 0.86 | 0.90 | 0.67 | 0.00 | 0.37 | 1.00 | 1.00 | 1.00 |\n| T cell | 13 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.35 | 0.93 | 0.68 | 0.92 |"
 }

celltypist.pkl

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metadata.json

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-{
-    "popv_version": "0.5.0",
-    "anndata_version": "0.11.3",
-    "setup_dict": {
-        "ref_labels_key": "popv_labels",
-        "ref_batch_key": "batch_key",
-        "unknown_celltype_label": "unassigned"
-    },
-    "prediction_keys": [
-        "popv_celltypist_prediction",
-        "popv_knn_bbknn_prediction",
-        "popv_knn_harmony_prediction",
-        "popv_knn_on_scvi_prediction",
-        "popv_onclass_prediction",
-        "popv_scanvi_prediction",
-        "popv_svm_prediction",
-        "popv_xgboost_prediction"
-    ],
-    "method_kwargs": {},
-    "methods": [
-        "CELLTYPIST",
-        "KNN_BBKNN",
-        "KNN_HARMONY",
-        "KNN_SCVI",
-        "ONCLASS",
-        "SCANVI_POPV",
-        "Support_Vector",
-        "XGboost"
-    ],
-    "cellxgene_url": "https://cellxgene.cziscience.com/e/d77ec7d6-ef2e-49d6-9e79-05b7f8881484.cxg/"
-}

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preprocessing.json

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-        "ENSG00000101452",
         "ENSG00000101474",
         "ENSG00000101546",
         "ENSG00000101605",
         "ENSG00000101624",
         "ENSG00000101639",
         "ENSG00000101665",
-        "ENSG00000101670",
         "ENSG00000101751",
         "ENSG00000101782",
         "ENSG00000101888",
@@ -535,13 +513,12 @@
         "ENSG00000102786",
         "ENSG00000102804",
         "ENSG00000102870",
-        "ENSG00000102886",
         "ENSG00000102901",
         "ENSG00000102967",
         "ENSG00000102977",
         "ENSG00000102984",
+        "ENSG00000103021",
         "ENSG00000103042",
-        "ENSG00000103044",
         "ENSG00000103047",
         "ENSG00000103066",
         "ENSG00000103067",
@@ -577,7 +554,6 @@
         "ENSG00000104472",
         "ENSG00000104499",
         "ENSG00000104626",
-        "ENSG00000104689",
         "ENSG00000104728",
         "ENSG00000104738",
         "ENSG00000104756",
@@ -610,6 +586,7 @@
         "ENSG00000105516",
         "ENSG00000105520",
         "ENSG00000105523",
+        "ENSG00000105583",
         "ENSG00000105647",
         "ENSG00000105707",
         "ENSG00000105708",
@@ -627,6 +604,7 @@
         "ENSG00000105894",
         "ENSG00000105928",
         "ENSG00000105929",
+        "ENSG00000105948",
         "ENSG00000105963",
         "ENSG00000105971",
         "ENSG00000105982",
@@ -649,7 +627,6 @@
         "ENSG00000106804",
         "ENSG00000106868",
         "ENSG00000106952",
-        "ENSG00000107021",
         "ENSG00000107099",
         "ENSG00000107185",
         "ENSG00000107201",
@@ -664,7 +641,6 @@
         "ENSG00000107742",
         "ENSG00000107798",
         "ENSG00000107815",
-        "ENSG00000107816",
         "ENSG00000107833",
         "ENSG00000107937",
         "ENSG00000107960",
@@ -678,6 +654,7 @@
         "ENSG00000108381",
         "ENSG00000108387",
         "ENSG00000108423",
+        "ENSG00000108448",
         "ENSG00000108506",
         "ENSG00000108515",
         "ENSG00000108578",
@@ -686,7 +663,6 @@
         "ENSG00000108691",
         "ENSG00000108733",
         "ENSG00000108771",
-        "ENSG00000108786",
         "ENSG00000108797",
         "ENSG00000108798",
         "ENSG00000108799",
@@ -702,14 +678,12 @@
         "ENSG00000109321",
         "ENSG00000109466",
         "ENSG00000109471",
-        "ENSG00000109501",
         "ENSG00000109519",
         "ENSG00000109618",
         "ENSG00000109736",
         "ENSG00000109738",
         "ENSG00000109743",
         "ENSG00000109790",
-        "ENSG00000109846",
         "ENSG00000109861",
         "ENSG00000109943",
         "ENSG00000109956",
@@ -732,14 +706,11 @@
         "ENSG00000110848",
         "ENSG00000110852",
         "ENSG00000110876",
-        "ENSG00000110888",
-        "ENSG00000110906",
         "ENSG00000110931",
         "ENSG00000110934",
         "ENSG00000110944",
         "ENSG00000110955",
         "ENSG00000110958",
-        "ENSG00000111052",
         "ENSG00000111254",
         "ENSG00000111271",
         "ENSG00000111331",
@@ -752,18 +723,15 @@
         "ENSG00000111452",
         "ENSG00000111537",
         "ENSG00000111554",
-        "ENSG00000111581",
         "ENSG00000111602",
         "ENSG00000111640",
         "ENSG00000111653",
-        "ENSG00000111669",
         "ENSG00000111671",
         "ENSG00000111674",
         "ENSG00000111711",
         "ENSG00000111729",
         "ENSG00000111785",
         "ENSG00000111801",
-        "ENSG00000111816",
         "ENSG00000111912",
         "ENSG00000112029",
         "ENSG00000112079",
@@ -785,7 +753,6 @@
         "ENSG00000112759",
         "ENSG00000112773",
         "ENSG00000112782",
-        "ENSG00000112851",
         "ENSG00000112941",
         "ENSG00000112983",
         "ENSG00000113048",
@@ -811,10 +778,10 @@
         "ENSG00000114302",
         "ENSG00000114331",
         "ENSG00000114374",
+        "ENSG00000114405",
         "ENSG00000114423",
         "ENSG00000114473",
         "ENSG00000114529",
-        "ENSG00000114541",
         "ENSG00000114638",
         "ENSG00000114739",
         "ENSG00000114767",
@@ -853,7 +820,6 @@
         "ENSG00000115687",
         "ENSG00000115738",
         "ENSG00000115825",
-        "ENSG00000115827",
         "ENSG00000115828",
         "ENSG00000115841",
         "ENSG00000115875",
@@ -862,7 +828,6 @@
         "ENSG00000115947",
         "ENSG00000115956",
         "ENSG00000115970",
-        "ENSG00000115993",
         "ENSG00000115998",
         "ENSG00000116016",
         "ENSG00000116017",
@@ -886,7 +851,7 @@
         "ENSG00000116830",
         "ENSG00000116852",
         "ENSG00000116885",
-        "ENSG00000116906",
+        "ENSG00000116922",
         "ENSG00000116954",
         "ENSG00000116962",
         "ENSG00000117000",
@@ -898,22 +863,20 @@
         "ENSG00000117155",
         "ENSG00000117226",
         "ENSG00000117228",
-        "ENSG00000117242",
         "ENSG00000117281",
         "ENSG00000117298",
         "ENSG00000117385",
         "ENSG00000117408",
         "ENSG00000117411",
         "ENSG00000117472",
-        "ENSG00000117480",
         "ENSG00000117500",
         "ENSG00000117505",
+        "ENSG00000117525",
         "ENSG00000117560",
         "ENSG00000117586",
         "ENSG00000117593",
         "ENSG00000117597",
         "ENSG00000117616",
-        "ENSG00000117625",
         "ENSG00000117640",
         "ENSG00000117643",
         "ENSG00000117707",
@@ -945,7 +908,6 @@
         "ENSG00000119147",
         "ENSG00000119185",
         "ENSG00000119231",
-        "ENSG00000119280",
         "ENSG00000119397",
         "ENSG00000119401",
         "ENSG00000119403",
@@ -960,7 +922,6 @@
         "ENSG00000119636",
         "ENSG00000119638",
         "ENSG00000119661",
-        "ENSG00000119703",
         "ENSG00000119714",
         "ENSG00000119777",
         "ENSG00000119801",
@@ -1013,6 +974,7 @@
         "ENSG00000121966",
         "ENSG00000122012",
         "ENSG00000122025",
+        "ENSG00000122043",
         "ENSG00000122122",
         "ENSG00000122133",
         "ENSG00000122176",
@@ -1043,7 +1005,6 @@
         "ENSG00000123106",
         "ENSG00000123130",
         "ENSG00000123136",
-        "ENSG00000123146",
         "ENSG00000123213",
         "ENSG00000123219",
         "ENSG00000123329",
@@ -1063,6 +1024,7 @@
         "ENSG00000124067",
         "ENSG00000124107",
         "ENSG00000124120",
+        "ENSG00000124157",
         "ENSG00000124181",
         "ENSG00000124203",
         "ENSG00000124216",
@@ -1073,7 +1035,6 @@
         "ENSG00000124370",
         "ENSG00000124459",
         "ENSG00000124508",
-        "ENSG00000124532",
         "ENSG00000124571",
         "ENSG00000124574",
         "ENSG00000124608",
@@ -1106,6 +1067,7 @@
         "ENSG00000125630",
         "ENSG00000125650",
         "ENSG00000125726",
+        "ENSG00000125730",
         "ENSG00000125735",
         "ENSG00000125740",
         "ENSG00000125779",
@@ -1128,7 +1090,6 @@
         "ENSG00000126790",
         "ENSG00000126803",
         "ENSG00000126814",
-        "ENSG00000126821",
         "ENSG00000126822",
         "ENSG00000126838",
         "ENSG00000126878",
@@ -1165,12 +1126,12 @@
         "ENSG00000128594",
         "ENSG00000128694",
         "ENSG00000128708",
+        "ENSG00000128713",
         "ENSG00000128973",
         "ENSG00000128989",
         "ENSG00000129009",
         "ENSG00000129028",
         "ENSG00000129151",
-        "ENSG00000129219",
         "ENSG00000129295",
         "ENSG00000129315",
         "ENSG00000129355",
@@ -1225,6 +1186,7 @@
         "ENSG00000131080",
         "ENSG00000131115",
         "ENSG00000131153",
+        "ENSG00000131187",
         "ENSG00000131188",
         "ENSG00000131323",
         "ENSG00000131351",
@@ -1233,6 +1195,7 @@
         "ENSG00000131470",
         "ENSG00000131504",
         "ENSG00000131584",
+        "ENSG00000131591",
         "ENSG00000131626",
         "ENSG00000131634",
         "ENSG00000131697",
@@ -1251,7 +1214,6 @@
         "ENSG00000132182",
         "ENSG00000132205",
         "ENSG00000132274",
-        "ENSG00000132275",
         "ENSG00000132305",
         "ENSG00000132321",
         "ENSG00000132330",
@@ -1322,9 +1284,7 @@
         "ENSG00000134461",
         "ENSG00000134539",
         "ENSG00000134545",
-        "ENSG00000134575",
         "ENSG00000134594",
-        "ENSG00000134597",
         "ENSG00000134602",
         "ENSG00000134627",
         "ENSG00000134780",
@@ -1362,14 +1322,10 @@
         "ENSG00000135480",
         "ENSG00000135482",
         "ENSG00000135519",
-        "ENSG00000135541",
-        "ENSG00000135549",
         "ENSG00000135596",
-        "ENSG00000135597",
         "ENSG00000135604",
         "ENSG00000135622",
         "ENSG00000135631",
-        "ENSG00000135637",
         "ENSG00000135678",
         "ENSG00000135722",
         "ENSG00000135723",
@@ -1431,7 +1387,6 @@
         "ENSG00000136999",
         "ENSG00000137033",
         "ENSG00000137040",
-        "ENSG00000137055",
         "ENSG00000137094",
         "ENSG00000137101",
         "ENSG00000137124",
@@ -1448,7 +1403,6 @@
         "ENSG00000137434",
         "ENSG00000137460",
         "ENSG00000137462",
-        "ENSG00000137474",
         "ENSG00000137491",
         "ENSG00000137496",
         "ENSG00000137502",
@@ -1458,7 +1412,6 @@
         "ENSG00000137672",
         "ENSG00000137699",
         "ENSG00000137709",
-        "ENSG00000137713",
         "ENSG00000137714",
         "ENSG00000137726",
         "ENSG00000137752",
@@ -1474,7 +1427,6 @@
         "ENSG00000137875",
         "ENSG00000137959",
         "ENSG00000137962",
-        "ENSG00000137965",
         "ENSG00000138030",
         "ENSG00000138035",
         "ENSG00000138050",
@@ -1498,10 +1450,10 @@
         "ENSG00000138386",
         "ENSG00000138413",
         "ENSG00000138434",
-        "ENSG00000138459",
         "ENSG00000138496",
         "ENSG00000138592",
         "ENSG00000138623",
+        "ENSG00000138641",
         "ENSG00000138642",
         "ENSG00000138663",
         "ENSG00000138670",
@@ -1563,9 +1515,7 @@
         "ENSG00000140403",
         "ENSG00000140450",
         "ENSG00000140463",
-        "ENSG00000140474",
         "ENSG00000140511",
-        "ENSG00000140521",
         "ENSG00000140525",
         "ENSG00000140527",
         "ENSG00000140543",
@@ -1589,8 +1539,8 @@
         "ENSG00000140993",
         "ENSG00000141012",
         "ENSG00000141040",
-        "ENSG00000141098",
         "ENSG00000141127",
+        "ENSG00000141219",
         "ENSG00000141232",
         "ENSG00000141279",
         "ENSG00000141298",
@@ -1604,6 +1554,7 @@
         "ENSG00000141527",
         "ENSG00000141569",
         "ENSG00000141577",
+        "ENSG00000141622",
         "ENSG00000141639",
         "ENSG00000141682",
         "ENSG00000141699",
@@ -1627,7 +1578,6 @@
         "ENSG00000142733",
         "ENSG00000142794",
         "ENSG00000142871",
-        "ENSG00000142875",
         "ENSG00000142892",
         "ENSG00000142920",
         "ENSG00000142961",
@@ -1680,17 +1630,14 @@
         "ENSG00000144381",
         "ENSG00000144407",
         "ENSG00000144485",
-        "ENSG00000144647",
         "ENSG00000144648",
         "ENSG00000144649",
         "ENSG00000144659",
-        "ENSG00000144736",
         "ENSG00000144792",
         "ENSG00000144802",
         "ENSG00000144810",
         "ENSG00000144824",
         "ENSG00000144837",
-        "ENSG00000144843",
         "ENSG00000144959",
         "ENSG00000145214",
         "ENSG00000145284",
@@ -1754,7 +1701,6 @@
         "ENSG00000147481",
         "ENSG00000147509",
         "ENSG00000147536",
-        "ENSG00000147576",
         "ENSG00000147604",
         "ENSG00000147650",
         "ENSG00000147853",
@@ -1772,7 +1718,6 @@
         "ENSG00000148400",
         "ENSG00000148411",
         "ENSG00000148459",
-        "ENSG00000148468",
         "ENSG00000148484",
         "ENSG00000148516",
         "ENSG00000148600",
@@ -1781,7 +1726,6 @@
         "ENSG00000148803",
         "ENSG00000148814",
         "ENSG00000148832",
-        "ENSG00000148908",
         "ENSG00000148925",
         "ENSG00000148926",
         "ENSG00000148935",
@@ -1804,7 +1748,7 @@
         "ENSG00000149564",
         "ENSG00000149636",
         "ENSG00000149658",
-        "ENSG00000149679",
+        "ENSG00000149716",
         "ENSG00000149782",
         "ENSG00000149922",
         "ENSG00000149970",
@@ -1844,7 +1788,6 @@
         "ENSG00000152076",
         "ENSG00000152078",
         "ENSG00000152223",
-        "ENSG00000152234",
         "ENSG00000152256",
         "ENSG00000152332",
         "ENSG00000152382",
@@ -1855,7 +1798,6 @@
         "ENSG00000152457",
         "ENSG00000152467",
         "ENSG00000152475",
-        "ENSG00000152518",
         "ENSG00000152556",
         "ENSG00000152582",
         "ENSG00000152583",
@@ -1883,6 +1825,7 @@
         "ENSG00000153714",
         "ENSG00000153721",
         "ENSG00000153767",
+        "ENSG00000153790",
         "ENSG00000153832",
         "ENSG00000153885",
         "ENSG00000153896",
@@ -1908,16 +1851,13 @@
         "ENSG00000154760",
         "ENSG00000154783",
         "ENSG00000154814",
-        "ENSG00000154930",
         "ENSG00000154957",
         "ENSG00000155016",
         "ENSG00000155034",
         "ENSG00000155052",
-        "ENSG00000155085",
         "ENSG00000155090",
         "ENSG00000155093",
         "ENSG00000155100",
-        "ENSG00000155158",
         "ENSG00000155252",
         "ENSG00000155254",
         "ENSG00000155275",
@@ -1942,7 +1882,6 @@
         "ENSG00000155906",
         "ENSG00000155926",
         "ENSG00000155962",
-        "ENSG00000155970",
         "ENSG00000155975",
         "ENSG00000156050",
         "ENSG00000156136",
@@ -1967,7 +1906,6 @@
         "ENSG00000157111",
         "ENSG00000157191",
         "ENSG00000157193",
-        "ENSG00000157224",
         "ENSG00000157240",
         "ENSG00000157303",
         "ENSG00000157350",
@@ -1976,6 +1914,7 @@
         "ENSG00000157423",
         "ENSG00000157429",
         "ENSG00000157470",
+        "ENSG00000157502",
         "ENSG00000157514",
         "ENSG00000157538",
         "ENSG00000157551",
@@ -2000,7 +1939,6 @@
         "ENSG00000158428",
         "ENSG00000158457",
         "ENSG00000158458",
-        "ENSG00000158483",
         "ENSG00000158552",
         "ENSG00000158555",
         "ENSG00000158560",
@@ -2010,7 +1948,6 @@
         "ENSG00000158792",
         "ENSG00000158806",
         "ENSG00000158882",
-        "ENSG00000158966",
         "ENSG00000159055",
         "ENSG00000159063",
         "ENSG00000159082",
@@ -2030,6 +1967,7 @@
         "ENSG00000159496",
         "ENSG00000159579",
         "ENSG00000159618",
+        "ENSG00000159648",
         "ENSG00000159674",
         "ENSG00000159713",
         "ENSG00000159761",
@@ -2089,6 +2027,7 @@
         "ENSG00000161929",
         "ENSG00000162063",
         "ENSG00000162066",
+        "ENSG00000162148",
         "ENSG00000162341",
         "ENSG00000162368",
         "ENSG00000162377",
@@ -2181,25 +2120,21 @@
         "ENSG00000163734",
         "ENSG00000163739",
         "ENSG00000163746",
-        "ENSG00000163755",
         "ENSG00000163781",
         "ENSG00000163795",
         "ENSG00000163803",
-        "ENSG00000163811",
         "ENSG00000163815",
         "ENSG00000163820",
         "ENSG00000163823",
         "ENSG00000163827",
         "ENSG00000163864",
         "ENSG00000163867",
-        "ENSG00000163874",
         "ENSG00000163877",
         "ENSG00000163904",
         "ENSG00000163909",
         "ENSG00000163913",
         "ENSG00000163923",
         "ENSG00000163935",
-        "ENSG00000163945",
         "ENSG00000163956",
         "ENSG00000163975",
         "ENSG00000163995",
@@ -2240,7 +2175,6 @@
         "ENSG00000164692",
         "ENSG00000164761",
         "ENSG00000164796",
-        "ENSG00000164808",
         "ENSG00000164818",
         "ENSG00000164850",
         "ENSG00000164920",
@@ -2252,16 +2186,16 @@
         "ENSG00000164949",
         "ENSG00000164951",
         "ENSG00000164953",
+        "ENSG00000164972",
         "ENSG00000164976",
         "ENSG00000165028",
         "ENSG00000165030",
         "ENSG00000165046",
         "ENSG00000165071",
         "ENSG00000165115",
-        "ENSG00000165125",
+        "ENSG00000165118",
         "ENSG00000165152",
         "ENSG00000165168",
-        "ENSG00000165259",
         "ENSG00000165271",
         "ENSG00000165282",
         "ENSG00000165300",
@@ -2379,7 +2313,6 @@
         "ENSG00000167552",
         "ENSG00000167554",
         "ENSG00000167562",
-        "ENSG00000167613",
         "ENSG00000167614",
         "ENSG00000167625",
         "ENSG00000167637",
@@ -2397,7 +2330,6 @@
         "ENSG00000167881",
         "ENSG00000167900",
         "ENSG00000167904",
-        "ENSG00000167920",
         "ENSG00000167967",
         "ENSG00000167972",
         "ENSG00000167981",
@@ -2406,7 +2338,6 @@
         "ENSG00000168036",
         "ENSG00000168060",
         "ENSG00000168062",
-        "ENSG00000168096",
         "ENSG00000168101",
         "ENSG00000168116",
         "ENSG00000168143",
@@ -2418,7 +2349,6 @@
         "ENSG00000168264",
         "ENSG00000168297",
         "ENSG00000168306",
-        "ENSG00000168309",
         "ENSG00000168329",
         "ENSG00000168350",
         "ENSG00000168386",
@@ -2440,6 +2370,7 @@
         "ENSG00000168661",
         "ENSG00000168672",
         "ENSG00000168685",
+        "ENSG00000168703",
         "ENSG00000168743",
         "ENSG00000168778",
         "ENSG00000168781",
@@ -2452,7 +2383,6 @@
         "ENSG00000168876",
         "ENSG00000168907",
         "ENSG00000168994",
-        "ENSG00000169031",
         "ENSG00000169105",
         "ENSG00000169116",
         "ENSG00000169129",
@@ -2512,7 +2442,6 @@
         "ENSG00000170442",
         "ENSG00000170468",
         "ENSG00000170469",
-        "ENSG00000170471",
         "ENSG00000170522",
         "ENSG00000170549",
         "ENSG00000170561",
@@ -2525,7 +2454,6 @@
         "ENSG00000170791",
         "ENSG00000170837",
         "ENSG00000170855",
-        "ENSG00000170909",
         "ENSG00000170917",
         "ENSG00000170959",
         "ENSG00000170962",
@@ -2574,7 +2502,6 @@
         "ENSG00000171757",
         "ENSG00000171759",
         "ENSG00000171766",
-        "ENSG00000171790",
         "ENSG00000171811",
         "ENSG00000171812",
         "ENSG00000171817",
@@ -2618,7 +2545,6 @@
         "ENSG00000173227",
         "ENSG00000173230",
         "ENSG00000173275",
-        "ENSG00000173281",
         "ENSG00000173369",
         "ENSG00000173391",
         "ENSG00000173432",
@@ -2636,12 +2562,14 @@
         "ENSG00000173875",
         "ENSG00000173894",
         "ENSG00000173898",
+        "ENSG00000173947",
         "ENSG00000173950",
         "ENSG00000174007",
         "ENSG00000174013",
         "ENSG00000174125",
         "ENSG00000174137",
         "ENSG00000174151",
+        "ENSG00000174171",
         "ENSG00000174206",
         "ENSG00000174233",
         "ENSG00000174236",
@@ -2692,7 +2620,6 @@
         "ENSG00000175445",
         "ENSG00000175449",
         "ENSG00000175489",
-        "ENSG00000175497",
         "ENSG00000175536",
         "ENSG00000175538",
         "ENSG00000175544",
@@ -2710,6 +2637,7 @@
         "ENSG00000175920",
         "ENSG00000176022",
         "ENSG00000176024",
+        "ENSG00000176049",
         "ENSG00000176055",
         "ENSG00000176058",
         "ENSG00000176083",
@@ -2719,6 +2647,7 @@
         "ENSG00000176208",
         "ENSG00000176225",
         "ENSG00000176293",
+        "ENSG00000176320",
         "ENSG00000176371",
         "ENSG00000176390",
         "ENSG00000176399",
@@ -2735,7 +2664,6 @@
         "ENSG00000176884",
         "ENSG00000176890",
         "ENSG00000176896",
-        "ENSG00000176971",
         "ENSG00000177084",
         "ENSG00000177125",
         "ENSG00000177133",
@@ -2751,7 +2679,6 @@
         "ENSG00000177409",
         "ENSG00000177426",
         "ENSG00000177427",
-        "ENSG00000177432",
         "ENSG00000177453",
         "ENSG00000177459",
         "ENSG00000177575",
@@ -2793,7 +2720,6 @@
         "ENSG00000178927",
         "ENSG00000179023",
         "ENSG00000179115",
-        "ENSG00000179151",
         "ENSG00000179152",
         "ENSG00000179165",
         "ENSG00000179335",
@@ -2818,6 +2744,7 @@
         "ENSG00000180113",
         "ENSG00000180190",
         "ENSG00000180257",
+        "ENSG00000180264",
         "ENSG00000180340",
         "ENSG00000180346",
         "ENSG00000180353",
@@ -2835,6 +2762,7 @@
         "ENSG00000180855",
         "ENSG00000180871",
         "ENSG00000180875",
+        "ENSG00000180884",
         "ENSG00000180917",
         "ENSG00000180979",
         "ENSG00000181004",
@@ -2882,7 +2810,6 @@
         "ENSG00000182511",
         "ENSG00000182557",
         "ENSG00000182578",
-        "ENSG00000182606",
         "ENSG00000182612",
         "ENSG00000182636",
         "ENSG00000182685",
@@ -2906,7 +2833,6 @@
         "ENSG00000183431",
         "ENSG00000183439",
         "ENSG00000183486",
-        "ENSG00000183508",
         "ENSG00000183513",
         "ENSG00000183542",
         "ENSG00000183549",
@@ -2916,7 +2842,6 @@
         "ENSG00000183655",
         "ENSG00000183665",
         "ENSG00000183682",
-        "ENSG00000183688",
         "ENSG00000183718",
         "ENSG00000183765",
         "ENSG00000183784",
@@ -2937,6 +2862,7 @@
         "ENSG00000184347",
         "ENSG00000184371",
         "ENSG00000184378",
+        "ENSG00000184441",
         "ENSG00000184445",
         "ENSG00000184451",
         "ENSG00000184465",
@@ -2960,6 +2886,7 @@
         "ENSG00000184967",
         "ENSG00000184979",
         "ENSG00000185002",
+        "ENSG00000185010",
         "ENSG00000185015",
         "ENSG00000185055",
         "ENSG00000185065",
@@ -2983,6 +2910,7 @@
         "ENSG00000185453",
         "ENSG00000185477",
         "ENSG00000185480",
+        "ENSG00000185483",
         "ENSG00000185504",
         "ENSG00000185513",
         "ENSG00000185522",
@@ -3015,7 +2943,6 @@
         "ENSG00000186073",
         "ENSG00000186081",
         "ENSG00000186104",
-        "ENSG00000186141",
         "ENSG00000186212",
         "ENSG00000186230",
         "ENSG00000186272",
@@ -3065,7 +2992,6 @@
         "ENSG00000187554",
         "ENSG00000187607",
         "ENSG00000187626",
-        "ENSG00000187642",
         "ENSG00000187650",
         "ENSG00000187676",
         "ENSG00000187678",
@@ -3230,10 +3156,11 @@
         "ENSG00000197535",
         "ENSG00000197540",
         "ENSG00000197555",
+        "ENSG00000197557",
         "ENSG00000197565",
+        "ENSG00000197576",
         "ENSG00000197580",
         "ENSG00000197619",
-        "ENSG00000197629",
         "ENSG00000197647",
         "ENSG00000197714",
         "ENSG00000197724",
@@ -3251,12 +3178,11 @@
         "ENSG00000197889",
         "ENSG00000197928",
         "ENSG00000197933",
-        "ENSG00000197935",
         "ENSG00000197937",
         "ENSG00000197943",
         "ENSG00000197948",
         "ENSG00000197951",
-        "ENSG00000198040",
+        "ENSG00000197978",
         "ENSG00000198046",
         "ENSG00000198075",
         "ENSG00000198081",
@@ -3287,7 +3213,6 @@
         "ENSG00000198517",
         "ENSG00000198521",
         "ENSG00000198522",
-        "ENSG00000198538",
         "ENSG00000198551",
         "ENSG00000198554",
         "ENSG00000198556",
@@ -3315,8 +3240,6 @@
         "ENSG00000198837",
         "ENSG00000198846",
         "ENSG00000198853",
-        "ENSG00000198870",
-        "ENSG00000198879",
         "ENSG00000198885",
         "ENSG00000198886",
         "ENSG00000198888",
@@ -3333,7 +3256,7 @@
         "ENSG00000198944",
         "ENSG00000198954",
         "ENSG00000198959",
-        "ENSG00000203288",
+        "ENSG00000203279",
         "ENSG00000203326",
         "ENSG00000203485",
         "ENSG00000203499",
@@ -3350,8 +3273,6 @@
         "ENSG00000204175",
         "ENSG00000204241",
         "ENSG00000204252",
-        "ENSG00000204261",
-        "ENSG00000204267",
         "ENSG00000204287",
         "ENSG00000204301",
         "ENSG00000204305",
@@ -3362,8 +3283,6 @@
         "ENSG00000204386",
         "ENSG00000204388",
         "ENSG00000204389",
-        "ENSG00000204394",
-        "ENSG00000204410",
         "ENSG00000204444",
         "ENSG00000204516",
         "ENSG00000204519",
@@ -3373,9 +3292,9 @@
         "ENSG00000204592",
         "ENSG00000204611",
         "ENSG00000204618",
+        "ENSG00000204620",
         "ENSG00000204681",
         "ENSG00000204713",
-        "ENSG00000204815",
         "ENSG00000204856",
         "ENSG00000204860",
         "ENSG00000204923",
@@ -3389,7 +3308,6 @@
         "ENSG00000205085",
         "ENSG00000205138",
         "ENSG00000205208",
-        "ENSG00000205268",
         "ENSG00000205269",
         "ENSG00000205302",
         "ENSG00000205413",
@@ -3409,15 +3327,11 @@
         "ENSG00000206052",
         "ENSG00000206075",
         "ENSG00000206140",
-        "ENSG00000206190",
-        "ENSG00000206344",
         "ENSG00000206559",
         "ENSG00000206561",
+        "ENSG00000206567",
         "ENSG00000211445",
         "ENSG00000211455",
-        "ENSG00000211689",
-        "ENSG00000211829",
-        "ENSG00000212719",
         "ENSG00000213185",
         "ENSG00000213213",
         "ENSG00000213390",
@@ -3425,7 +3339,6 @@
         "ENSG00000213424",
         "ENSG00000213468",
         "ENSG00000213516",
-        "ENSG00000213588",
         "ENSG00000213638",
         "ENSG00000213672",
         "ENSG00000213694",
@@ -3443,18 +3356,19 @@
         "ENSG00000214357",
         "ENSG00000214456",
         "ENSG00000214548",
+        "ENSG00000214708",
         "ENSG00000214870",
         "ENSG00000214894",
+        "ENSG00000215014",
         "ENSG00000215045",
+        "ENSG00000215067",
         "ENSG00000215217",
         "ENSG00000215251",
         "ENSG00000215301",
         "ENSG00000215375",
         "ENSG00000215788",
-        "ENSG00000215790",
         "ENSG00000215808",
         "ENSG00000216921",
-        "ENSG00000218739",
         "ENSG00000219481",
         "ENSG00000219545",
         "ENSG00000219626",
@@ -3466,23 +3380,22 @@
         "ENSG00000221890",
         "ENSG00000221909",
         "ENSG00000221916",
-        "ENSG00000221988",
         "ENSG00000221990",
         "ENSG00000221994",
         "ENSG00000222009",
         "ENSG00000222011",
+        "ENSG00000222043",
         "ENSG00000223442",
+        "ENSG00000223522",
         "ENSG00000223546",
         "ENSG00000223552",
         "ENSG00000223572",
+        "ENSG00000223797",
         "ENSG00000223799",
-        "ENSG00000223865",
-        "ENSG00000223923",
         "ENSG00000223960",
         "ENSG00000224023",
         "ENSG00000224046",
         "ENSG00000224086",
-        "ENSG00000224093",
         "ENSG00000224157",
         "ENSG00000224164",
         "ENSG00000224220",
@@ -3493,13 +3406,16 @@
         "ENSG00000224533",
         "ENSG00000224536",
         "ENSG00000224843",
+        "ENSG00000224848",
         "ENSG00000224958",
         "ENSG00000225177",
         "ENSG00000225194",
+        "ENSG00000225205",
         "ENSG00000225265",
         "ENSG00000225285",
         "ENSG00000225342",
         "ENSG00000225439",
+        "ENSG00000225489",
         "ENSG00000225518",
         "ENSG00000225526",
         "ENSG00000225556",
@@ -3510,6 +3426,7 @@
         "ENSG00000225791",
         "ENSG00000225793",
         "ENSG00000225855",
+        "ENSG00000225950",
         "ENSG00000225975",
         "ENSG00000226091",
         "ENSG00000226124",
@@ -3517,7 +3434,8 @@
         "ENSG00000226167",
         "ENSG00000226200",
         "ENSG00000226251",
-        "ENSG00000226445",
+        "ENSG00000226332",
+        "ENSG00000226644",
         "ENSG00000226648",
         "ENSG00000226754",
         "ENSG00000226791",
@@ -3527,23 +3445,27 @@
         "ENSG00000227014",
         "ENSG00000227039",
         "ENSG00000227155",
-        "ENSG00000227191",
         "ENSG00000227354",
         "ENSG00000227409",
+        "ENSG00000227540",
+        "ENSG00000227627",
         "ENSG00000227695",
         "ENSG00000228126",
+        "ENSG00000228172",
         "ENSG00000228192",
         "ENSG00000228242",
         "ENSG00000228262",
         "ENSG00000228288",
+        "ENSG00000228395",
         "ENSG00000228414",
+        "ENSG00000228427",
         "ENSG00000228486",
         "ENSG00000228506",
         "ENSG00000228598",
         "ENSG00000228784",
         "ENSG00000228801",
         "ENSG00000228812",
-        "ENSG00000228857",
+        "ENSG00000228863",
         "ENSG00000228878",
         "ENSG00000228918",
         "ENSG00000229056",
@@ -3566,18 +3488,19 @@
         "ENSG00000230555",
         "ENSG00000230797",
         "ENSG00000230844",
-        "ENSG00000230918",
-        "ENSG00000231074",
-        "ENSG00000231079",
         "ENSG00000231154",
         "ENSG00000231327",
+        "ENSG00000231329",
         "ENSG00000231389",
         "ENSG00000231473",
+        "ENSG00000231566",
         "ENSG00000231621",
+        "ENSG00000231731",
         "ENSG00000231742",
         "ENSG00000231764",
         "ENSG00000231768",
         "ENSG00000231806",
+        "ENSG00000231856",
         "ENSG00000231890",
         "ENSG00000231908",
         "ENSG00000231920",
@@ -3585,8 +3508,8 @@
         "ENSG00000232070",
         "ENSG00000232098",
         "ENSG00000232354",
+        "ENSG00000232386",
         "ENSG00000232453",
-        "ENSG00000232564",
         "ENSG00000232613",
         "ENSG00000232629",
         "ENSG00000232645",
@@ -3595,22 +3518,26 @@
         "ENSG00000232656",
         "ENSG00000232671",
         "ENSG00000232774",
+        "ENSG00000232807",
         "ENSG00000232810",
         "ENSG00000232912",
         "ENSG00000232931",
+        "ENSG00000232934",
         "ENSG00000232956",
         "ENSG00000233154",
+        "ENSG00000233230",
         "ENSG00000233237",
         "ENSG00000233334",
         "ENSG00000233554",
+        "ENSG00000233621",
         "ENSG00000233654",
         "ENSG00000233791",
         "ENSG00000233851",
+        "ENSG00000233967",
         "ENSG00000234028",
         "ENSG00000234076",
         "ENSG00000234127",
         "ENSG00000234171",
-        "ENSG00000234263",
         "ENSG00000234284",
         "ENSG00000234465",
         "ENSG00000234494",
@@ -3622,10 +3549,10 @@
         "ENSG00000234719",
         "ENSG00000234883",
         "ENSG00000234928",
+        "ENSG00000234961",
         "ENSG00000235016",
         "ENSG00000235109",
         "ENSG00000235159",
-        "ENSG00000235300",
         "ENSG00000235527",
         "ENSG00000235706",
         "ENSG00000235919",
@@ -3634,19 +3561,28 @@
         "ENSG00000236144",
         "ENSG00000236200",
         "ENSG00000236213",
+        "ENSG00000236255",
+        "ENSG00000236266",
         "ENSG00000236432",
         "ENSG00000236481",
         "ENSG00000236548",
         "ENSG00000236617",
+        "ENSG00000236663",
+        "ENSG00000236756",
         "ENSG00000236778",
         "ENSG00000236780",
+        "ENSG00000236833",
         "ENSG00000236915",
+        "ENSG00000236935",
         "ENSG00000237036",
         "ENSG00000237054",
         "ENSG00000237181",
         "ENSG00000237187",
         "ENSG00000237281",
+        "ENSG00000237343",
         "ENSG00000237399",
+        "ENSG00000237422",
+        "ENSG00000237461",
         "ENSG00000237499",
         "ENSG00000237512",
         "ENSG00000237989",
@@ -3654,13 +3590,17 @@
         "ENSG00000238121",
         "ENSG00000238197",
         "ENSG00000239213",
+        "ENSG00000239388",
+        "ENSG00000239407",
         "ENSG00000239453",
         "ENSG00000239946",
         "ENSG00000239998",
         "ENSG00000240005",
         "ENSG00000240038",
+        "ENSG00000240175",
         "ENSG00000240211",
         "ENSG00000240230",
+        "ENSG00000240401",
         "ENSG00000240498",
         "ENSG00000240583",
         "ENSG00000240859",
@@ -3690,10 +3630,13 @@
         "ENSG00000244165",
         "ENSG00000244265",
         "ENSG00000244405",
+        "ENSG00000244459",
         "ENSG00000244462",
         "ENSG00000244513",
+        "ENSG00000244541",
         "ENSG00000244586",
         "ENSG00000244968",
+        "ENSG00000245025",
         "ENSG00000245146",
         "ENSG00000245149",
         "ENSG00000245164",
@@ -3704,42 +3647,47 @@
         "ENSG00000245571",
         "ENSG00000245648",
         "ENSG00000245680",
+        "ENSG00000246022",
         "ENSG00000246089",
         "ENSG00000246145",
         "ENSG00000246174",
         "ENSG00000246223",
         "ENSG00000246273",
+        "ENSG00000246308",
         "ENSG00000246366",
-        "ENSG00000246379",
-        "ENSG00000246422",
         "ENSG00000246451",
         "ENSG00000246526",
         "ENSG00000246695",
         "ENSG00000247081",
+        "ENSG00000247134",
         "ENSG00000247240",
         "ENSG00000247400",
         "ENSG00000247572",
         "ENSG00000247626",
+        "ENSG00000247679",
         "ENSG00000247708",
         "ENSG00000247796",
+        "ENSG00000247934",
         "ENSG00000247950",
         "ENSG00000247982",
         "ENSG00000248008",
         "ENSG00000248019",
         "ENSG00000248049",
         "ENSG00000248092",
+        "ENSG00000248371",
         "ENSG00000248483",
         "ENSG00000248485",
+        "ENSG00000248559",
         "ENSG00000248663",
         "ENSG00000248693",
+        "ENSG00000248712",
         "ENSG00000248727",
-        "ENSG00000248898",
-        "ENSG00000249087",
         "ENSG00000249096",
         "ENSG00000249249",
         "ENSG00000249502",
         "ENSG00000249637",
         "ENSG00000249673",
+        "ENSG00000249679",
         "ENSG00000249709",
         "ENSG00000249715",
         "ENSG00000249993",
@@ -3748,24 +3696,29 @@
         "ENSG00000250073",
         "ENSG00000250155",
         "ENSG00000250159",
-        "ENSG00000250166",
         "ENSG00000250303",
         "ENSG00000250312",
-        "ENSG00000250508",
         "ENSG00000250548",
         "ENSG00000250565",
         "ENSG00000250616",
         "ENSG00000250742",
         "ENSG00000250802",
+        "ENSG00000251034",
+        "ENSG00000251131",
         "ENSG00000251192",
         "ENSG00000251247",
         "ENSG00000251279",
         "ENSG00000251364",
         "ENSG00000251369",
+        "ENSG00000251417",
         "ENSG00000251562",
+        "ENSG00000251615",
         "ENSG00000251629",
+        "ENSG00000251661",
+        "ENSG00000253106",
         "ENSG00000253210",
         "ENSG00000253304",
+        "ENSG00000253392",
         "ENSG00000253404",
         "ENSG00000253522",
         "ENSG00000253549",
@@ -3777,27 +3730,31 @@
         "ENSG00000253846",
         "ENSG00000253958",
         "ENSG00000254004",
-        "ENSG00000254206",
         "ENSG00000254266",
         "ENSG00000254369",
         "ENSG00000254415",
         "ENSG00000254469",
         "ENSG00000254473",
         "ENSG00000254703",
+        "ENSG00000254802",
         "ENSG00000254815",
         "ENSG00000255008",
+        "ENSG00000255026",
+        "ENSG00000255046",
         "ENSG00000255052",
         "ENSG00000255100",
         "ENSG00000255112",
         "ENSG00000255150",
         "ENSG00000255153",
         "ENSG00000255197",
+        "ENSG00000255320",
         "ENSG00000255398",
-        "ENSG00000255458",
         "ENSG00000255468",
         "ENSG00000255561",
+        "ENSG00000255621",
         "ENSG00000255733",
         "ENSG00000255760",
+        "ENSG00000255882",
         "ENSG00000256039",
         "ENSG00000256043",
         "ENSG00000256061",
@@ -3808,18 +3765,18 @@
         "ENSG00000256628",
         "ENSG00000256751",
         "ENSG00000256771",
-        "ENSG00000256806",
+        "ENSG00000256812",
         "ENSG00000256940",
-        "ENSG00000257023",
         "ENSG00000257103",
         "ENSG00000257135",
+        "ENSG00000257176",
         "ENSG00000257285",
         "ENSG00000257433",
         "ENSG00000257497",
-        "ENSG00000257698",
         "ENSG00000257913",
-        "ENSG00000258136",
         "ENSG00000258227",
+        "ENSG00000258302",
+        "ENSG00000258325",
         "ENSG00000258474",
         "ENSG00000258476",
         "ENSG00000258498",
@@ -3829,6 +3786,8 @@
         "ENSG00000258655",
         "ENSG00000258727",
         "ENSG00000258738",
+        "ENSG00000258752",
+        "ENSG00000258820",
         "ENSG00000258839",
         "ENSG00000258890",
         "ENSG00000259065",
@@ -3837,21 +3796,24 @@
         "ENSG00000259153",
         "ENSG00000259215",
         "ENSG00000259291",
+        "ENSG00000259321",
         "ENSG00000259343",
         "ENSG00000259430",
         "ENSG00000259448",
         "ENSG00000259456",
+        "ENSG00000259536",
         "ENSG00000259583",
         "ENSG00000259642",
         "ENSG00000259673",
         "ENSG00000259687",
         "ENSG00000259802",
-        "ENSG00000259826",
         "ENSG00000259877",
         "ENSG00000259943",
         "ENSG00000260018",
         "ENSG00000260219",
         "ENSG00000260220",
+        "ENSG00000260267",
+        "ENSG00000260274",
         "ENSG00000260278",
         "ENSG00000260314",
         "ENSG00000260329",
@@ -3864,25 +3826,30 @@
         "ENSG00000260625",
         "ENSG00000260630",
         "ENSG00000260708",
-        "ENSG00000260853",
+        "ENSG00000260733",
         "ENSG00000260992",
+        "ENSG00000261098",
         "ENSG00000261188",
-        "ENSG00000261189",
         "ENSG00000261302",
         "ENSG00000261326",
         "ENSG00000261366",
+        "ENSG00000261386",
         "ENSG00000261390",
         "ENSG00000261423",
-        "ENSG00000261437",
+        "ENSG00000261448",
         "ENSG00000261485",
-        "ENSG00000261488",
+        "ENSG00000261613",
         "ENSG00000261664",
         "ENSG00000261801",
+        "ENSG00000261840",
+        "ENSG00000261889",
         "ENSG00000262001",
         "ENSG00000262155",
         "ENSG00000262468",
+        "ENSG00000262580",
         "ENSG00000262655",
         "ENSG00000262686",
+        "ENSG00000262823",
         "ENSG00000263002",
         "ENSG00000263050",
         "ENSG00000263155",
@@ -3890,26 +3857,31 @@
         "ENSG00000263465",
         "ENSG00000263528",
         "ENSG00000263724",
+        "ENSG00000263731",
+        "ENSG00000263826",
         "ENSG00000263874",
+        "ENSG00000264112",
+        "ENSG00000264230",
         "ENSG00000264235",
-        "ENSG00000264247",
         "ENSG00000264575",
-        "ENSG00000264964",
+        "ENSG00000264666",
         "ENSG00000265096",
-        "ENSG00000265206",
+        "ENSG00000265218",
         "ENSG00000265458",
-        "ENSG00000265688",
         "ENSG00000265778",
         "ENSG00000265817",
+        "ENSG00000265907",
         "ENSG00000265972",
+        "ENSG00000265975",
         "ENSG00000266028",
-        "ENSG00000266053",
         "ENSG00000266173",
         "ENSG00000266256",
         "ENSG00000266904",
         "ENSG00000266913",
         "ENSG00000266916",
+        "ENSG00000266947",
         "ENSG00000266970",
+        "ENSG00000267011",
         "ENSG00000267040",
         "ENSG00000267107",
         "ENSG00000267128",
@@ -3918,88 +3890,116 @@
         "ENSG00000267278",
         "ENSG00000267302",
         "ENSG00000267322",
-        "ENSG00000267374",
-        "ENSG00000267394",
+        "ENSG00000267345",
         "ENSG00000267416",
         "ENSG00000267421",
         "ENSG00000267454",
         "ENSG00000267475",
         "ENSG00000267680",
+        "ENSG00000267698",
         "ENSG00000267710",
         "ENSG00000267871",
+        "ENSG00000267892",
         "ENSG00000268006",
         "ENSG00000268043",
+        "ENSG00000268218",
+        "ENSG00000268362",
+        "ENSG00000268584",
         "ENSG00000268895",
         "ENSG00000269190",
-        "ENSG00000269303",
+        "ENSG00000269194",
         "ENSG00000269343",
         "ENSG00000269696",
         "ENSG00000269720",
-        "ENSG00000269994",
+        "ENSG00000269889",
+        "ENSG00000269973",
         "ENSG00000270006",
-        "ENSG00000270049",
+        "ENSG00000270019",
+        "ENSG00000270175",
+        "ENSG00000270210",
+        "ENSG00000270361",
         "ENSG00000270362",
         "ENSG00000270419",
         "ENSG00000270547",
+        "ENSG00000270605",
         "ENSG00000270761",
+        "ENSG00000270765",
         "ENSG00000270820",
+        "ENSG00000271109",
         "ENSG00000271122",
-        "ENSG00000271335",
-        "ENSG00000271503",
+        "ENSG00000271380",
         "ENSG00000271576",
         "ENSG00000271605",
         "ENSG00000271614",
+        "ENSG00000271737",
+        "ENSG00000271780",
+        "ENSG00000271857",
+        "ENSG00000271918",
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