popV version: 0.6.0

.gitattributes

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OnClass.data-00000-of-00001

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OnClass.npz

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README.md

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----
-library_name: popV
-license: cc-by-4.0
-tags:
-- biology
-- genomics
-- single-cell
-- anndata_version:0.11.3
-- python_version:3.11.11
-- popV
-- 'tissue: Small_Intestine'
----
-
-Popular Vote (popV) model for automated cell type annotation of single-cell RNA-seq data. We provide here pretrained models
-for plug-in use in your own analysis.
-Follow our [tutorial](https://github.com/YosefLab/popV/blob/main/tabula_sapiens_tutorial.ipynb) to learn how to use the model for cell type annotation.
-
-# Model description
-
-Tabula Sapiens is a benchmark, first-draft human cell atlas of over 1.1M cells from 28 organs of 24 normal human subjects. This work is the product of the Tabula Sapiens Consortium. Taking the organs from the same individual controls for genetic background, age, environment, and epigenetic effects, and allows detailed analysis and comparison of cell types that are shared between tissues.
-
-**Link to CELLxGENE**:
-Link to the [data](https://cellxgene.cziscience.com/e/a357414d-2042-4eb5-95f0-c58604a18bdd.cxg/) in the CELLxGENE browser for interactive exploration of the data and download of the source data.
-
-**Training Code URL**:
-Not provided by uploader.
-
-# Metrics
-
-We provide here accuracies for each of the experts and the ensemble model. The validation set accuracies are
-computed on a 10% random subset of the data that was not used for training.
-
-| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |
-| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
-| enterocyte of epithelium proper of duodenum | 1336 | 0.92 | 0.93 | 0.92 | 0.79 | 0.00 | 0.87 | 0.91 | 0.93 | 0.94 |
-| enterocyte of epithelium proper of ileum | 627 | 0.96 | 0.96 | 0.92 | 0.56 | 0.00 | 0.75 | 0.97 | 0.97 | 0.98 |
-| CD4-positive, alpha-beta T cell | 532 | 0.89 | 0.89 | 0.92 | 0.68 | 0.00 | 0.78 | 0.89 | 0.89 | 0.91 |
-| CD8-positive, alpha-beta T cell | 349 | 0.86 | 0.78 | 0.91 | 0.54 | 0.00 | 0.74 | 0.82 | 0.82 | 0.89 |
-| small intestine goblet cell | 214 | 0.94 | 0.94 | 0.95 | 0.90 | 0.00 | 0.89 | 0.93 | 0.92 | 0.94 |
-| paneth cell of epithelium of small intestine | 194 | 0.71 | 0.74 | 0.80 | 0.74 | 0.00 | 0.65 | 0.71 | 0.79 | 0.83 |
-| enterocyte of epithelium proper of small intestine | 149 | 0.59 | 0.59 | 0.66 | 0.56 | 0.00 | 0.52 | 0.75 | 0.77 | 0.81 |
-| activated CD8-positive, alpha-beta T cell | 103 | 0.79 | 0.43 | 0.87 | 0.42 | 0.00 | 0.57 | 0.67 | 0.73 | 0.80 |
-| plasma cell | 80 | 0.99 | 0.99 | 0.98 | 0.97 | 0.00 | 0.96 | 0.98 | 0.98 | 0.99 |
-| B cell | 70 | 0.99 | 0.99 | 0.99 | 0.98 | 0.00 | 0.99 | 0.99 | 0.96 | 0.99 |
-| intestinal crypt stem cell of small intestine | 56 | 0.40 | 0.53 | 0.54 | 0.33 | 0.00 | 0.29 | 0.40 | 0.47 | 0.55 |
-| activated CD4-positive, alpha-beta T cell | 64 | 0.43 | 0.25 | 0.57 | 0.16 | 0.00 | 0.37 | 0.46 | 0.52 | 0.55 |
-| fibroblast | 45 | 0.99 | 0.99 | 0.99 | 0.95 | 0.00 | 1.00 | 1.00 | 0.99 | 0.99 |
-| intestinal tuft cell | 54 | 1.00 | 1.00 | 0.99 | 0.96 | 0.00 | 0.97 | 1.00 | 1.00 | 1.00 |
-| enterocyte of epithelium proper of jejunum | 46 | 0.11 | 0.12 | 0.23 | 0.18 | 0.00 | 0.08 | 0.51 | 0.51 | 0.31 |
-| macrophage | 49 | 0.82 | 0.92 | 0.92 | 0.85 | 0.00 | 0.97 | 0.94 | 0.91 | 0.92 |
-| enteroendocrine cell of small intestine | 19 | 0.86 | 0.84 | 0.86 | 0.79 | 0.00 | 0.63 | 0.84 | 0.80 | 0.84 |
-| mast cell | 24 | 0.98 | 1.00 | 0.98 | 0.94 | 0.00 | 0.98 | 1.00 | 1.00 | 1.00 |
-| natural killer cell | 19 | 0.00 | 0.26 | 0.30 | 0.00 | 0.00 | 0.21 | 0.14 | 0.36 | 0.24 |
-| enteroglial cell | 20 | 0.95 | 0.95 | 0.97 | 0.81 | 0.00 | 0.98 | 0.98 | 0.98 | 0.98 |
-| endothelial cell of arteriole | 15 | 0.77 | 0.94 | 0.77 | 0.63 | 0.00 | 0.82 | 1.00 | 0.90 | 0.91 |
-| gamma-delta T cell | 9 | 0.62 | 0.67 | 0.71 | 0.12 | 0.00 | 0.48 | 0.56 | 0.56 | 0.76 |
-| naive thymus-derived CD4-positive, alpha-beta T cell | 8 | 0.00 | 0.20 | 0.40 | 0.15 | 0.00 | 0.70 | 0.70 | 0.50 | 0.55 |
-| monocyte | 8 | 0.64 | 0.78 | 0.80 | 0.59 | 0.00 | 0.88 | 0.82 | 0.74 | 0.82 |
-| neutrophil | 6 | 0.57 | 0.91 | 0.75 | 0.20 | 0.00 | 0.75 | 0.92 | 0.67 | 0.83 |
-| endothelial cell of lymphatic vessel | 5 | 1.00 | 1.00 | 1.00 | 0.60 | 0.00 | 0.83 | 1.00 | 1.00 | 1.00 |
-| endothelial cell of venule | 6 | 0.00 | 0.83 | 0.67 | 0.22 | 0.00 | 0.83 | 0.92 | 0.91 | 0.91 |
-| myofibroblast cell | 5 | 0.50 | 1.00 | 1.00 | 0.33 | 0.00 | 0.67 | 1.00 | 1.00 | 1.00 |
-| transit amplifying cell of small intestine | 2 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
-| innate lymphoid cell | 3 | 0.80 | 0.80 | 0.40 | 0.67 | 0.00 | 0.50 | 0.00 | 0.80 | 1.00 |
-| pericyte | 4 | 0.00 | 1.00 | 1.00 | 0.00 | 0.00 | 0.80 | 1.00 | 1.00 | 1.00 |
-| regulatory T cell | 4 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.67 | 0.40 | 0.40 | 0.00 |
-| myeloid dendritic cell | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
-
-The train accuracies are computed on the training data.
-
-| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |
-| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
-| enterocyte of epithelium proper of duodenum | 12159 | 0.92 | 0.90 | 0.95 | 0.86 | 0.00 | 0.94 | 0.92 | 0.93 | 0.96 |
-| enterocyte of epithelium proper of ileum | 5850 | 0.97 | 0.95 | 0.95 | 0.75 | 0.00 | 0.95 | 0.98 | 0.98 | 0.99 |
-| CD4-positive, alpha-beta T cell | 4623 | 0.91 | 0.89 | 0.95 | 0.83 | 0.00 | 0.89 | 0.91 | 0.91 | 0.95 |
-| CD8-positive, alpha-beta T cell | 3123 | 0.85 | 0.75 | 0.93 | 0.69 | 0.00 | 0.84 | 0.83 | 0.87 | 0.93 |
-| small intestine goblet cell | 1830 | 0.93 | 0.94 | 0.96 | 0.90 | 0.00 | 0.88 | 0.94 | 0.94 | 0.95 |
-| paneth cell of epithelium of small intestine | 1659 | 0.70 | 0.72 | 0.81 | 0.79 | 0.00 | 0.72 | 0.77 | 0.81 | 0.86 |
-| enterocyte of epithelium proper of small intestine | 1266 | 0.58 | 0.43 | 0.80 | 0.80 | 0.00 | 0.80 | 0.79 | 0.85 | 0.89 |
-| activated CD8-positive, alpha-beta T cell | 1044 | 0.76 | 0.40 | 0.91 | 0.72 | 0.00 | 0.80 | 0.79 | 0.84 | 0.91 |
-| plasma cell | 742 | 0.99 | 0.98 | 0.99 | 0.99 | 0.00 | 0.98 | 0.99 | 0.99 | 0.99 |
-| B cell | 703 | 0.99 | 0.99 | 0.99 | 0.99 | 0.00 | 0.99 | 0.99 | 0.99 | 0.99 |
-| intestinal crypt stem cell of small intestine | 531 | 0.34 | 0.43 | 0.53 | 0.44 | 0.00 | 0.36 | 0.60 | 0.65 | 0.66 |
-| activated CD4-positive, alpha-beta T cell | 506 | 0.43 | 0.32 | 0.74 | 0.42 | 0.00 | 0.58 | 0.64 | 0.66 | 0.77 |
-| fibroblast | 448 | 0.97 | 0.97 | 0.98 | 0.93 | 0.00 | 0.98 | 0.99 | 0.98 | 0.99 |
-| intestinal tuft cell | 394 | 0.97 | 0.97 | 0.97 | 0.96 | 0.00 | 0.95 | 0.99 | 0.99 | 0.98 |
-| enterocyte of epithelium proper of jejunum | 359 | 0.21 | 0.01 | 0.82 | 0.36 | 0.00 | 0.95 | 0.60 | 0.55 | 0.88 |
-| macrophage | 317 | 0.82 | 0.92 | 0.93 | 0.91 | 0.00 | 0.98 | 0.99 | 0.99 | 0.98 |
-| enteroendocrine cell of small intestine | 245 | 0.92 | 0.91 | 0.94 | 0.87 | 0.00 | 0.69 | 0.92 | 0.93 | 0.95 |
-| mast cell | 226 | 0.95 | 0.96 | 0.98 | 0.96 | 0.00 | 0.94 | 0.99 | 0.99 | 0.98 |
-| natural killer cell | 142 | 0.00 | 0.15 | 0.47 | 0.33 | 0.00 | 0.46 | 0.75 | 0.80 | 0.85 |
-| enteroglial cell | 122 | 0.93 | 0.93 | 0.95 | 0.89 | 0.00 | 0.95 | 0.99 | 0.99 | 0.98 |
-| endothelial cell of arteriole | 117 | 0.80 | 0.95 | 0.91 | 0.79 | 0.00 | 0.95 | 0.99 | 1.00 | 0.97 |
-| gamma-delta T cell | 112 | 0.73 | 0.70 | 0.78 | 0.52 | 0.00 | 0.89 | 0.94 | 0.96 | 0.96 |
-| naive thymus-derived CD4-positive, alpha-beta T cell | 107 | 0.00 | 0.27 | 0.42 | 0.35 | 0.00 | 0.88 | 0.91 | 0.90 | 0.77 |
-| monocyte | 70 | 0.75 | 0.87 | 0.81 | 0.76 | 0.00 | 0.90 | 1.00 | 1.00 | 1.00 |
-| neutrophil | 71 | 0.71 | 0.73 | 0.81 | 0.74 | 0.00 | 0.91 | 1.00 | 0.99 | 0.95 |
-| endothelial cell of lymphatic vessel | 68 | 0.98 | 0.98 | 0.99 | 0.87 | 0.00 | 0.94 | 0.99 | 0.99 | 0.99 |
-| endothelial cell of venule | 46 | 0.00 | 0.87 | 0.83 | 0.45 | 0.00 | 0.99 | 0.95 | 0.95 | 0.92 |
-| myofibroblast cell | 46 | 0.64 | 0.94 | 0.95 | 0.75 | 0.00 | 0.70 | 0.97 | 0.95 | 0.95 |
-| transit amplifying cell of small intestine | 32 | 0.00 | 0.00 | 0.54 | 0.17 | 0.00 | 0.28 | 0.85 | 0.90 | 0.92 |
-| innate lymphoid cell | 31 | 0.64 | 0.67 | 0.68 | 0.59 | 0.00 | 0.66 | 1.00 | 1.00 | 0.95 |
-| pericyte | 20 | 0.00 | 0.98 | 0.98 | 0.60 | 0.00 | 0.93 | 1.00 | 1.00 | 1.00 |
-| regulatory T cell | 11 | 0.00 | 0.29 | 0.43 | 0.00 | 0.00 | 0.91 | 1.00 | 1.00 | 0.84 |
-| myeloid dendritic cell | 11 | 0.00 | 0.43 | 0.50 | 0.50 | 0.00 | 0.88 | 1.00 | 1.00 | 0.91 |
-
-</details>
-
-
-# References
-
-Tabula Sapiens reveals transcription factor expression, senescence effects, and sex-specific features in cell types from 28 human organs and tissues, The Tabula Sapiens Consortium; bioRxiv, doi: https://doi.org/10.1101/2024.12.03.626516

accuracies.json

@@ -1,4 +1,4 @@
 {
-    "query_accuracy": "| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |\n| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |\n| enterocyte of epithelium proper of duodenum | 1336 | 0.92 | 0.93 | 0.92 | 0.79 | 0.00 | 0.87 | 0.91 | 0.93 | 0.94 |\n| enterocyte of epithelium proper of ileum | 627 | 0.96 | 0.96 | 0.92 | 0.56 | 0.00 | 0.75 | 0.97 | 0.97 | 0.98 |\n| CD4-positive, alpha-beta T cell | 532 | 0.89 | 0.89 | 0.92 | 0.68 | 0.00 | 0.78 | 0.89 | 0.89 | 0.91 |\n| CD8-positive, alpha-beta T cell | 349 | 0.86 | 0.78 | 0.91 | 0.54 | 0.00 | 0.74 | 0.82 | 0.82 | 0.89 |\n| small intestine goblet cell | 214 | 0.94 | 0.94 | 0.95 | 0.90 | 0.00 | 0.89 | 0.93 | 0.92 | 0.94 |\n| paneth cell of epithelium of small intestine | 194 | 0.71 | 0.74 | 0.80 | 0.74 | 0.00 | 0.65 | 0.71 | 0.79 | 0.83 |\n| enterocyte of epithelium proper of small intestine | 149 | 0.59 | 0.59 | 0.66 | 0.56 | 0.00 | 0.52 | 0.75 | 0.77 | 0.81 |\n| activated CD8-positive, alpha-beta T cell | 103 | 0.79 | 0.43 | 0.87 | 0.42 | 0.00 | 0.57 | 0.67 | 0.73 | 0.80 |\n| plasma cell | 80 | 0.99 | 0.99 | 0.98 | 0.97 | 0.00 | 0.96 | 0.98 | 0.98 | 0.99 |\n| B cell | 70 | 0.99 | 0.99 | 0.99 | 0.98 | 0.00 | 0.99 | 0.99 | 0.96 | 0.99 |\n| intestinal crypt stem cell of small intestine | 56 | 0.40 | 0.53 | 0.54 | 0.33 | 0.00 | 0.29 | 0.40 | 0.47 | 0.55 |\n| activated CD4-positive, alpha-beta T cell | 64 | 0.43 | 0.25 | 0.57 | 0.16 | 0.00 | 0.37 | 0.46 | 0.52 | 0.55 |\n| fibroblast | 45 | 0.99 | 0.99 | 0.99 | 0.95 | 0.00 | 1.00 | 1.00 | 0.99 | 0.99 |\n| intestinal tuft cell | 54 | 1.00 | 1.00 | 0.99 | 0.96 | 0.00 | 0.97 | 1.00 | 1.00 | 1.00 |\n| enterocyte of epithelium proper of jejunum | 46 | 0.11 | 0.12 | 0.23 | 0.18 | 0.00 | 0.08 | 0.51 | 0.51 | 0.31 |\n| macrophage | 49 | 0.82 | 0.92 | 0.92 | 0.85 | 0.00 | 0.97 | 0.94 | 0.91 | 0.92 |\n| enteroendocrine cell of small intestine | 19 | 0.86 | 0.84 | 0.86 | 0.79 | 0.00 | 0.63 | 0.84 | 0.80 | 0.84 |\n| mast cell | 24 | 0.98 | 1.00 | 0.98 | 0.94 | 0.00 | 0.98 | 1.00 | 1.00 | 1.00 |\n| natural killer cell | 19 | 0.00 | 0.26 | 0.30 | 0.00 | 0.00 | 0.21 | 0.14 | 0.36 | 0.24 |\n| enteroglial cell | 20 | 0.95 | 0.95 | 0.97 | 0.81 | 0.00 | 0.98 | 0.98 | 0.98 | 0.98 |\n| endothelial cell of arteriole | 15 | 0.77 | 0.94 | 0.77 | 0.63 | 0.00 | 0.82 | 1.00 | 0.90 | 0.91 |\n| gamma-delta T cell | 9 | 0.62 | 0.67 | 0.71 | 0.12 | 0.00 | 0.48 | 0.56 | 0.56 | 0.76 |\n| naive thymus-derived CD4-positive, alpha-beta T cell | 8 | 0.00 | 0.20 | 0.40 | 0.15 | 0.00 | 0.70 | 0.70 | 0.50 | 0.55 |\n| monocyte | 8 | 0.64 | 0.78 | 0.80 | 0.59 | 0.00 | 0.88 | 0.82 | 0.74 | 0.82 |\n| neutrophil | 6 | 0.57 | 0.91 | 0.75 | 0.20 | 0.00 | 0.75 | 0.92 | 0.67 | 0.83 |\n| endothelial cell of lymphatic vessel | 5 | 1.00 | 1.00 | 1.00 | 0.60 | 0.00 | 0.83 | 1.00 | 1.00 | 1.00 |\n| endothelial cell of venule | 6 | 0.00 | 0.83 | 0.67 | 0.22 | 0.00 | 0.83 | 0.92 | 0.91 | 0.91 |\n| myofibroblast cell | 5 | 0.50 | 1.00 | 1.00 | 0.33 | 0.00 | 0.67 | 1.00 | 1.00 | 1.00 |\n| transit amplifying cell of small intestine | 2 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |\n| innate lymphoid cell | 3 | 0.80 | 0.80 | 0.40 | 0.67 | 0.00 | 0.50 | 0.00 | 0.80 | 1.00 |\n| pericyte | 4 | 0.00 | 1.00 | 1.00 | 0.00 | 0.00 | 0.80 | 1.00 | 1.00 | 1.00 |\n| regulatory T cell | 4 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.67 | 0.40 | 0.40 | 0.00 |\n| myeloid dendritic cell | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |",
-    "ref_accuracy": "| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |\n| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |\n| enterocyte of epithelium proper of duodenum | 12159 | 0.92 | 0.90 | 0.95 | 0.86 | 0.00 | 0.94 | 0.92 | 0.93 | 0.96 |\n| enterocyte of epithelium proper of ileum | 5850 | 0.97 | 0.95 | 0.95 | 0.75 | 0.00 | 0.95 | 0.98 | 0.98 | 0.99 |\n| CD4-positive, alpha-beta T cell | 4623 | 0.91 | 0.89 | 0.95 | 0.83 | 0.00 | 0.89 | 0.91 | 0.91 | 0.95 |\n| CD8-positive, alpha-beta T cell | 3123 | 0.85 | 0.75 | 0.93 | 0.69 | 0.00 | 0.84 | 0.83 | 0.87 | 0.93 |\n| small intestine goblet cell | 1830 | 0.93 | 0.94 | 0.96 | 0.90 | 0.00 | 0.88 | 0.94 | 0.94 | 0.95 |\n| paneth cell of epithelium of small intestine | 1659 | 0.70 | 0.72 | 0.81 | 0.79 | 0.00 | 0.72 | 0.77 | 0.81 | 0.86 |\n| enterocyte of epithelium proper of small intestine | 1266 | 0.58 | 0.43 | 0.80 | 0.80 | 0.00 | 0.80 | 0.79 | 0.85 | 0.89 |\n| activated CD8-positive, alpha-beta T cell | 1044 | 0.76 | 0.40 | 0.91 | 0.72 | 0.00 | 0.80 | 0.79 | 0.84 | 0.91 |\n| plasma cell | 742 | 0.99 | 0.98 | 0.99 | 0.99 | 0.00 | 0.98 | 0.99 | 0.99 | 0.99 |\n| B cell | 703 | 0.99 | 0.99 | 0.99 | 0.99 | 0.00 | 0.99 | 0.99 | 0.99 | 0.99 |\n| intestinal crypt stem cell of small intestine | 531 | 0.34 | 0.43 | 0.53 | 0.44 | 0.00 | 0.36 | 0.60 | 0.65 | 0.66 |\n| activated CD4-positive, alpha-beta T cell | 506 | 0.43 | 0.32 | 0.74 | 0.42 | 0.00 | 0.58 | 0.64 | 0.66 | 0.77 |\n| fibroblast | 448 | 0.97 | 0.97 | 0.98 | 0.93 | 0.00 | 0.98 | 0.99 | 0.98 | 0.99 |\n| intestinal tuft cell | 394 | 0.97 | 0.97 | 0.97 | 0.96 | 0.00 | 0.95 | 0.99 | 0.99 | 0.98 |\n| enterocyte of epithelium proper of jejunum | 359 | 0.21 | 0.01 | 0.82 | 0.36 | 0.00 | 0.95 | 0.60 | 0.55 | 0.88 |\n| macrophage | 317 | 0.82 | 0.92 | 0.93 | 0.91 | 0.00 | 0.98 | 0.99 | 0.99 | 0.98 |\n| enteroendocrine cell of small intestine | 245 | 0.92 | 0.91 | 0.94 | 0.87 | 0.00 | 0.69 | 0.92 | 0.93 | 0.95 |\n| mast cell | 226 | 0.95 | 0.96 | 0.98 | 0.96 | 0.00 | 0.94 | 0.99 | 0.99 | 0.98 |\n| natural killer cell | 142 | 0.00 | 0.15 | 0.47 | 0.33 | 0.00 | 0.46 | 0.75 | 0.80 | 0.85 |\n| enteroglial cell | 122 | 0.93 | 0.93 | 0.95 | 0.89 | 0.00 | 0.95 | 0.99 | 0.99 | 0.98 |\n| endothelial cell of arteriole | 117 | 0.80 | 0.95 | 0.91 | 0.79 | 0.00 | 0.95 | 0.99 | 1.00 | 0.97 |\n| gamma-delta T cell | 112 | 0.73 | 0.70 | 0.78 | 0.52 | 0.00 | 0.89 | 0.94 | 0.96 | 0.96 |\n| naive thymus-derived CD4-positive, alpha-beta T cell | 107 | 0.00 | 0.27 | 0.42 | 0.35 | 0.00 | 0.88 | 0.91 | 0.90 | 0.77 |\n| monocyte | 70 | 0.75 | 0.87 | 0.81 | 0.76 | 0.00 | 0.90 | 1.00 | 1.00 | 1.00 |\n| neutrophil | 71 | 0.71 | 0.73 | 0.81 | 0.74 | 0.00 | 0.91 | 1.00 | 0.99 | 0.95 |\n| endothelial cell of lymphatic vessel | 68 | 0.98 | 0.98 | 0.99 | 0.87 | 0.00 | 0.94 | 0.99 | 0.99 | 0.99 |\n| endothelial cell of venule | 46 | 0.00 | 0.87 | 0.83 | 0.45 | 0.00 | 0.99 | 0.95 | 0.95 | 0.92 |\n| myofibroblast cell | 46 | 0.64 | 0.94 | 0.95 | 0.75 | 0.00 | 0.70 | 0.97 | 0.95 | 0.95 |\n| transit amplifying cell of small intestine | 32 | 0.00 | 0.00 | 0.54 | 0.17 | 0.00 | 0.28 | 0.85 | 0.90 | 0.92 |\n| innate lymphoid cell | 31 | 0.64 | 0.67 | 0.68 | 0.59 | 0.00 | 0.66 | 1.00 | 1.00 | 0.95 |\n| pericyte | 20 | 0.00 | 0.98 | 0.98 | 0.60 | 0.00 | 0.93 | 1.00 | 1.00 | 1.00 |\n| regulatory T cell | 11 | 0.00 | 0.29 | 0.43 | 0.00 | 0.00 | 0.91 | 1.00 | 1.00 | 0.84 |\n| myeloid dendritic cell | 11 | 0.00 | 0.43 | 0.50 | 0.50 | 0.00 | 0.88 | 1.00 | 1.00 | 0.91 |"
+    "query_accuracy": "| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |\n| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |\n| enterocyte of epithelium proper of duodenum | 1351 | 0.93 | 0.91 | 0.91 | 0.80 | 0.00 | 0.83 | 0.91 | 0.93 | 0.96 |\n| enterocyte of epithelium proper of ileum | 630 | 0.97 | 0.92 | 0.91 | 0.50 | 0.00 | 0.72 | 0.97 | 0.97 | 0.97 |\n| CD4-positive, alpha-beta T cell | 532 | 0.88 | 0.88 | 0.91 | 0.83 | 0.00 | 0.76 | 0.88 | 0.87 | 0.93 |\n| CD8-positive, alpha-beta T cell | 346 | 0.85 | 0.75 | 0.90 | 0.74 | 0.00 | 0.73 | 0.80 | 0.83 | 0.90 |\n| small intestine goblet cell | 214 | 0.94 | 0.94 | 0.93 | 0.90 | 0.00 | 0.92 | 0.93 | 0.95 | 0.94 |\n| paneth cell of epithelium of small intestine | 183 | 0.70 | 0.78 | 0.80 | 0.72 | 0.00 | 0.62 | 0.70 | 0.73 | 0.82 |\n| enterocyte of epithelium proper of small intestine | 150 | 0.62 | 0.53 | 0.79 | 0.49 | 0.00 | 0.58 | 0.72 | 0.78 | 0.85 |\n| activated CD8-positive, alpha-beta T cell | 101 | 0.75 | 0.32 | 0.87 | 0.36 | 0.00 | 0.51 | 0.70 | 0.73 | 0.79 |\n| BEST4+ enteroycte | 78 | 0.81 | 0.84 | 0.86 | 0.83 | 0.00 | 0.86 | 0.81 | 0.81 | 0.88 |\n| plasma cell | 77 | 0.97 | 0.98 | 0.99 | 0.99 | 0.00 | 0.97 | 0.99 | 0.99 | 0.99 |\n| B cell | 68 | 0.99 | 0.98 | 0.99 | 0.99 | 0.00 | 0.96 | 0.97 | 0.98 | 0.99 |\n| intestinal crypt stem cell of small intestine | 56 | 0.35 | 0.43 | 0.46 | 0.39 | 0.00 | 0.45 | 0.42 | 0.50 | 0.51 |\n| activated CD4-positive, alpha-beta T cell | 66 | 0.43 | 0.15 | 0.55 | 0.44 | 0.00 | 0.41 | 0.48 | 0.51 | 0.64 |\n| fibroblast | 46 | 1.00 | 0.99 | 0.99 | 0.99 | 0.00 | 0.98 | 0.99 | 0.97 | 0.99 |\n| intestinal tuft cell | 52 | 1.00 | 1.00 | 1.00 | 0.98 | 0.00 | 0.99 | 1.00 | 1.00 | 1.00 |\n| enterocyte of epithelium proper of jejunum | 47 | 0.14 | 0.00 | 0.15 | 0.08 | 0.00 | 0.16 | 0.55 | 0.51 | 0.31 |\n| macrophage | 47 | 0.91 | 0.93 | 0.94 | 0.91 | 0.00 | 0.93 | 0.94 | 0.91 | 0.93 |\n| enteroendocrine cell of small intestine | 20 | 0.88 | 0.89 | 0.87 | 0.90 | 0.00 | 0.90 | 0.81 | 0.86 | 0.87 |\n| mast cell | 24 | 0.96 | 0.98 | 0.98 | 1.00 | 0.00 | 0.94 | 0.98 | 0.98 | 0.98 |\n| natural killer cell | 20 | 0.00 | 0.09 | 0.25 | 0.15 | 0.00 | 0.20 | 0.10 | 0.39 | 0.22 |\n| enteroglial cell | 20 | 0.95 | 0.95 | 0.95 | 0.98 | 0.00 | 0.89 | 0.95 | 0.95 | 0.98 |\n| endothelial cell of arteriole | 15 | 0.70 | 0.88 | 0.76 | 0.80 | 0.00 | 0.84 | 0.97 | 0.90 | 0.88 |\n| gamma-delta T cell | 9 | 0.55 | 0.48 | 0.53 | 0.27 | 0.00 | 0.58 | 0.38 | 0.58 | 0.67 |\n| naive thymus-derived CD4-positive, alpha-beta T cell | 8 | 0.00 | 0.40 | 0.00 | 0.00 | 0.00 | 0.32 | 0.60 | 0.57 | 0.40 |\n| monocyte | 8 | 0.82 | 0.80 | 0.77 | 0.59 | 0.00 | 0.80 | 0.74 | 0.78 | 0.80 |\n| neutrophil | 4 | 0.40 | 0.67 | 0.60 | 0.86 | 0.00 | 0.43 | 0.89 | 0.75 | 0.67 |\n| endothelial cell of lymphatic vessel | 8 | 1.00 | 1.00 | 1.00 | 0.80 | 0.00 | 0.80 | 1.00 | 1.00 | 1.00 |\n| endothelial cell of venule | 6 | 0.00 | 0.80 | 0.20 | 0.20 | 0.00 | 0.71 | 0.92 | 0.91 | 0.73 |\n| myofibroblast cell | 6 | 0.67 | 0.91 | 0.92 | 0.80 | 0.00 | 1.00 | 0.83 | 1.00 | 1.00 |\n| transit amplifying cell of small intestine | 2 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 |\n| innate lymphoid cell | 3 | 0.86 | 0.00 | 0.50 | 0.40 | 0.00 | 0.55 | 0.33 | 0.80 | 1.00 |\n| pericyte | 4 | 0.67 | 1.00 | 1.00 | 0.75 | 0.00 | 1.00 | 1.00 | 1.00 | 1.00 |\n| regulatory T cell | 3 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.50 | 0.00 |\n| myeloid dendritic cell | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |",
+    "ref_accuracy": "| Cell Type | N cells |  celltypist |  knn bbknn |  knn harmony |  knn on scvi |  onclass |  scanvi |  svm |  xgboost | Consensus Prediction |\n| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |\n| enterocyte of epithelium proper of duodenum | 12144 | 0.93 | 0.92 | 0.93 | 0.82 | 0.00 | 0.94 | 0.92 | 0.94 | 0.97 |\n| enterocyte of epithelium proper of ileum | 5847 | 0.97 | 0.93 | 0.92 | 0.56 | 0.00 | 0.95 | 0.98 | 0.98 | 0.99 |\n| CD4-positive, alpha-beta T cell | 4623 | 0.89 | 0.90 | 0.93 | 0.84 | 0.00 | 0.90 | 0.91 | 0.91 | 0.95 |\n| CD8-positive, alpha-beta T cell | 3126 | 0.83 | 0.79 | 0.90 | 0.77 | 0.00 | 0.83 | 0.84 | 0.86 | 0.92 |\n| small intestine goblet cell | 1830 | 0.94 | 0.95 | 0.96 | 0.91 | 0.00 | 0.94 | 0.96 | 0.96 | 0.96 |\n| paneth cell of epithelium of small intestine | 1670 | 0.74 | 0.81 | 0.83 | 0.75 | 0.00 | 0.68 | 0.79 | 0.81 | 0.87 |\n| enterocyte of epithelium proper of small intestine | 1265 | 0.60 | 0.51 | 0.83 | 0.54 | 0.00 | 0.84 | 0.82 | 0.86 | 0.89 |\n| activated CD8-positive, alpha-beta T cell | 1046 | 0.71 | 0.43 | 0.88 | 0.58 | 0.00 | 0.79 | 0.78 | 0.83 | 0.89 |\n| BEST4+ enteroycte | 802 | 0.81 | 0.86 | 0.87 | 0.80 | 0.00 | 0.86 | 0.83 | 0.85 | 0.89 |\n| plasma cell | 745 | 0.98 | 0.99 | 0.99 | 0.99 | 0.00 | 0.98 | 0.98 | 0.99 | 0.99 |\n| B cell | 705 | 0.99 | 0.99 | 0.99 | 0.98 | 0.00 | 0.97 | 0.99 | 0.99 | 0.99 |\n| intestinal crypt stem cell of small intestine | 531 | 0.36 | 0.47 | 0.46 | 0.36 | 0.00 | 0.54 | 0.67 | 0.72 | 0.69 |\n| activated CD4-positive, alpha-beta T cell | 504 | 0.43 | 0.37 | 0.63 | 0.45 | 0.00 | 0.56 | 0.61 | 0.63 | 0.76 |\n| fibroblast | 447 | 0.97 | 0.97 | 0.97 | 0.97 | 0.00 | 0.97 | 0.98 | 0.99 | 0.98 |\n| intestinal tuft cell | 396 | 0.96 | 0.97 | 0.97 | 0.96 | 0.00 | 0.98 | 0.98 | 0.99 | 0.98 |\n| enterocyte of epithelium proper of jejunum | 358 | 0.18 | 0.00 | 0.68 | 0.07 | 0.00 | 0.82 | 0.56 | 0.54 | 0.82 |\n| macrophage | 319 | 0.88 | 0.91 | 0.89 | 0.90 | 0.00 | 0.97 | 0.99 | 0.98 | 0.95 |\n| enteroendocrine cell of small intestine | 244 | 0.92 | 0.91 | 0.92 | 0.88 | 0.00 | 0.90 | 0.94 | 0.97 | 0.93 |\n| mast cell | 226 | 0.95 | 0.96 | 0.96 | 0.97 | 0.00 | 0.95 | 0.98 | 0.98 | 0.97 |\n| natural killer cell | 141 | 0.00 | 0.15 | 0.35 | 0.20 | 0.00 | 0.55 | 0.79 | 0.85 | 0.85 |\n| enteroglial cell | 122 | 0.92 | 0.92 | 0.92 | 0.94 | 0.00 | 0.89 | 0.99 | 0.99 | 0.98 |\n| endothelial cell of arteriole | 117 | 0.77 | 0.94 | 0.87 | 0.85 | 0.00 | 0.92 | 0.99 | 1.00 | 0.95 |\n| gamma-delta T cell | 112 | 0.71 | 0.73 | 0.67 | 0.62 | 0.00 | 0.82 | 0.92 | 0.96 | 0.95 |\n| naive thymus-derived CD4-positive, alpha-beta T cell | 107 | 0.00 | 0.42 | 0.09 | 0.25 | 0.00 | 0.71 | 0.85 | 0.87 | 0.74 |\n| monocyte | 70 | 0.85 | 0.87 | 0.67 | 0.67 | 0.00 | 0.97 | 0.97 | 1.00 | 0.99 |\n| neutrophil | 73 | 0.63 | 0.77 | 0.76 | 0.77 | 0.00 | 0.85 | 0.99 | 0.99 | 0.87 |\n| endothelial cell of lymphatic vessel | 65 | 0.98 | 0.98 | 0.98 | 0.91 | 0.00 | 0.94 | 0.98 | 0.98 | 0.98 |\n| endothelial cell of venule | 46 | 0.00 | 0.87 | 0.66 | 0.46 | 0.00 | 0.82 | 0.96 | 0.97 | 0.93 |\n| myofibroblast cell | 45 | 0.75 | 0.94 | 0.94 | 0.85 | 0.00 | 0.89 | 0.95 | 0.95 | 0.95 |\n| transit amplifying cell of small intestine | 32 | 0.00 | 0.00 | 0.46 | 0.00 | 0.00 | 0.63 | 0.75 | 0.90 | 0.86 |\n| innate lymphoid cell | 31 | 0.64 | 0.63 | 0.60 | 0.43 | 0.00 | 0.78 | 0.93 | 0.98 | 0.91 |\n| pericyte | 20 | 0.62 | 0.98 | 0.93 | 0.76 | 0.00 | 0.95 | 1.00 | 1.00 | 0.98 |\n| regulatory T cell | 12 | 0.00 | 0.15 | 0.00 | 0.14 | 0.00 | 0.69 | 0.92 | 0.92 | 0.29 |\n| myeloid dendritic cell | 11 | 0.00 | 0.56 | 0.40 | 0.00 | 0.00 | 0.67 | 1.00 | 1.00 | 0.84 |"
 }

celltypist.pkl

@@ -1,3 +1,3 @@
 version https://git-lfs.github.com/spec/v1
-oid sha256:d0452c651405e0c2543f0c09dce9ad16d76e6277b25feb7c393bc55dfc71d054
-size 698305
+oid sha256:f0d73e38342524a817ef2a7478e7b3dc80fb2124a3760f2c67ff61c39b3a76e5
+size 714329

svm_classifier_cuml.joblib → faiss_index.index

@@ -1,3 +1,3 @@
 version https://git-lfs.github.com/spec/v1
-oid sha256:7acd9b29763db5ecfa569a88ba56f55838f09aa49de2e5cb2bbd5f8a7c6e21f4
-size 563963
+oid sha256:8fb063f7e11e39410f25e0645f3d8353964250a197008274df92683798df43bc
+size 7566445

harmony_knn_classifier.joblib → harmony_knn_classifier.index

@@ -1,3 +1,3 @@
 version https://git-lfs.github.com/spec/v1
-oid sha256:e89ee254efeaf4ef7397b85b8c37f2baf24e84e8c879cc5654c94c3f30dde631
-size 28486965
+oid sha256:7450d2d0f93975b8e19e149ece349bc67a1858dcb89cad5ab6b87b7b0b2ecabc
+size 7566445

metadata.json

@@ -1,31 +0,0 @@
-{
-    "popv_version": "0.5.0",
-    "anndata_version": "0.11.3",
-    "setup_dict": {
-        "ref_labels_key": "popv_labels",
-        "ref_batch_key": "batch_key",
-        "unknown_celltype_label": "unassigned"
-    },
-    "prediction_keys": [
-        "popv_celltypist_prediction",
-        "popv_knn_bbknn_prediction",
-        "popv_knn_harmony_prediction",
-        "popv_knn_on_scvi_prediction",
-        "popv_onclass_prediction",
-        "popv_scanvi_prediction",
-        "popv_svm_prediction",
-        "popv_xgboost_prediction"
-    ],
-    "method_kwargs": {},
-    "methods": [
-        "CELLTYPIST",
-        "KNN_BBKNN",
-        "KNN_HARMONY",
-        "KNN_SCVI",
-        "ONCLASS",
-        "SCANVI_POPV",
-        "Support_Vector",
-        "XGboost"
-    ],
-    "cellxgene_url": "https://cellxgene.cziscience.com/e/a357414d-2042-4eb5-95f0-c58604a18bdd.cxg/"
-}

minified_ref_adata.h5ad

@@ -1,3 +0,0 @@
-version https://git-lfs.github.com/spec/v1
-oid sha256:b34bf7d6c59d729ac0015b387eb602a8c7120f24f9cb5606a97e622a16c959cc
-size 60730172

preprocessing.json

@@ -1,5 +1,6 @@
 {
     "gene_names": [
+        "ENSG00000000460",
         "ENSG00000000938",
         "ENSG00000000971",
         "ENSG00000001461",
@@ -41,7 +42,6 @@
         "ENSG00000008300",
         "ENSG00000008394",
         "ENSG00000008516",
-        "ENSG00000009830",
         "ENSG00000010165",
         "ENSG00000010219",
         "ENSG00000010256",
@@ -69,6 +69,7 @@
         "ENSG00000013588",
         "ENSG00000013619",
         "ENSG00000016402",
+        "ENSG00000016490",
         "ENSG00000016864",
         "ENSG00000018280",
         "ENSG00000018408",
@@ -82,7 +83,6 @@
         "ENSG00000021645",
         "ENSG00000021762",
         "ENSG00000022267",
-        "ENSG00000022556",
         "ENSG00000023041",
         "ENSG00000023191",
         "ENSG00000023445",
@@ -95,8 +95,6 @@
         "ENSG00000026103",
         "ENSG00000026508",
         "ENSG00000026751",
-        "ENSG00000027697",
-        "ENSG00000028137",
         "ENSG00000029534",
         "ENSG00000029993",
         "ENSG00000030304",
@@ -118,19 +116,19 @@
         "ENSG00000040531",
         "ENSG00000041880",
         "ENSG00000041982",
-        "ENSG00000041988",
         "ENSG00000042062",
         "ENSG00000042317",
         "ENSG00000042493",
         "ENSG00000042980",
         "ENSG00000043143",
-        "ENSG00000043462",
         "ENSG00000043514",
+        "ENSG00000044012",
         "ENSG00000044459",
         "ENSG00000044574",
         "ENSG00000046653",
         "ENSG00000047457",
         "ENSG00000047597",
+        "ENSG00000047621",
         "ENSG00000048028",
         "ENSG00000048392",
         "ENSG00000048462",
@@ -156,15 +154,13 @@
         "ENSG00000055118",
         "ENSG00000055147",
         "ENSG00000056277",
-        "ENSG00000056558",
         "ENSG00000056736",
         "ENSG00000056998",
-        "ENSG00000057019",
         "ENSG00000057252",
+        "ENSG00000057593",
         "ENSG00000057657",
         "ENSG00000058085",
         "ENSG00000058404",
-        "ENSG00000058729",
         "ENSG00000058799",
         "ENSG00000059122",
         "ENSG00000059377",
@@ -189,7 +185,6 @@
         "ENSG00000063761",
         "ENSG00000064102",
         "ENSG00000064115",
-        "ENSG00000064225",
         "ENSG00000064270",
         "ENSG00000064300",
         "ENSG00000064313",
@@ -263,7 +258,6 @@
         "ENSG00000074590",
         "ENSG00000074657",
         "ENSG00000074800",
-        "ENSG00000074935",
         "ENSG00000075073",
         "ENSG00000075624",
         "ENSG00000076003",
@@ -306,7 +300,6 @@
         "ENSG00000083093",
         "ENSG00000083290",
         "ENSG00000083520",
-        "ENSG00000083544",
         "ENSG00000083814",
         "ENSG00000083817",
         "ENSG00000083844",
@@ -390,7 +383,6 @@
         "ENSG00000091972",
         "ENSG00000091986",
         "ENSG00000092295",
-        "ENSG00000092330",
         "ENSG00000092621",
         "ENSG00000092820",
         "ENSG00000092871",
@@ -402,7 +394,6 @@
         "ENSG00000094914",
         "ENSG00000094916",
         "ENSG00000094963",
-        "ENSG00000095002",
         "ENSG00000095110",
         "ENSG00000095209",
         "ENSG00000095303",
@@ -414,6 +405,7 @@
         "ENSG00000096088",
         "ENSG00000096093",
         "ENSG00000096384",
+        "ENSG00000096395",
         "ENSG00000096968",
         "ENSG00000097046",
         "ENSG00000099250",
@@ -432,7 +424,6 @@
         "ENSG00000100036",
         "ENSG00000100056",
         "ENSG00000100060",
-        "ENSG00000100068",
         "ENSG00000100116",
         "ENSG00000100150",
         "ENSG00000100206",
@@ -477,7 +468,6 @@
         "ENSG00000100628",
         "ENSG00000100714",
         "ENSG00000100739",
-        "ENSG00000100744",
         "ENSG00000100767",
         "ENSG00000100802",
         "ENSG00000100884",
@@ -566,7 +556,6 @@
         "ENSG00000103423",
         "ENSG00000103496",
         "ENSG00000103507",
-        "ENSG00000103528",
         "ENSG00000103591",
         "ENSG00000103707",
         "ENSG00000103710",
@@ -615,6 +604,7 @@
         "ENSG00000105281",
         "ENSG00000105376",
         "ENSG00000105383",
+        "ENSG00000105388",
         "ENSG00000105419",
         "ENSG00000105479",
         "ENSG00000105497",
@@ -650,7 +640,6 @@
         "ENSG00000106211",
         "ENSG00000106236",
         "ENSG00000106263",
-        "ENSG00000106266",
         "ENSG00000106333",
         "ENSG00000106348",
         "ENSG00000106366",
@@ -679,6 +668,7 @@
         "ENSG00000107731",
         "ENSG00000107742",
         "ENSG00000107796",
+        "ENSG00000107807",
         "ENSG00000107815",
         "ENSG00000107874",
         "ENSG00000107937",
@@ -691,6 +681,7 @@
         "ENSG00000108387",
         "ENSG00000108405",
         "ENSG00000108443",
+        "ENSG00000108448",
         "ENSG00000108506",
         "ENSG00000108511",
         "ENSG00000108528",
@@ -701,7 +692,6 @@
         "ENSG00000108691",
         "ENSG00000108733",
         "ENSG00000108771",
-        "ENSG00000108797",
         "ENSG00000108798",
         "ENSG00000108821",
         "ENSG00000108839",
@@ -737,7 +727,6 @@
         "ENSG00000110442",
         "ENSG00000110448",
         "ENSG00000110455",
-        "ENSG00000110492",
         "ENSG00000110651",
         "ENSG00000110723",
         "ENSG00000110799",
@@ -803,6 +792,7 @@
         "ENSG00000112312",
         "ENSG00000112320",
         "ENSG00000112486",
+        "ENSG00000112494",
         "ENSG00000112561",
         "ENSG00000112562",
         "ENSG00000112679",
@@ -813,7 +803,7 @@
         "ENSG00000112812",
         "ENSG00000112874",
         "ENSG00000112877",
-        "ENSG00000112996",
+        "ENSG00000112936",
         "ENSG00000113048",
         "ENSG00000113088",
         "ENSG00000113108",
@@ -837,6 +827,7 @@
         "ENSG00000114354",
         "ENSG00000114378",
         "ENSG00000114388",
+        "ENSG00000114405",
         "ENSG00000114491",
         "ENSG00000114698",
         "ENSG00000114737",
@@ -862,6 +853,7 @@
         "ENSG00000115318",
         "ENSG00000115325",
         "ENSG00000115380",
+        "ENSG00000115386",
         "ENSG00000115414",
         "ENSG00000115421",
         "ENSG00000115461",
@@ -888,7 +880,6 @@
         "ENSG00000116120",
         "ENSG00000116128",
         "ENSG00000116132",
-        "ENSG00000116133",
         "ENSG00000116157",
         "ENSG00000116161",
         "ENSG00000116209",
@@ -904,7 +895,6 @@
         "ENSG00000116514",
         "ENSG00000116525",
         "ENSG00000116544",
-        "ENSG00000116691",
         "ENSG00000116698",
         "ENSG00000116701",
         "ENSG00000116741",
@@ -921,10 +911,10 @@
         "ENSG00000116885",
         "ENSG00000116906",
         "ENSG00000116918",
+        "ENSG00000116922",
         "ENSG00000116962",
         "ENSG00000116983",
         "ENSG00000117009",
-        "ENSG00000117010",
         "ENSG00000117013",
         "ENSG00000117016",
         "ENSG00000117090",
@@ -943,6 +933,7 @@
         "ENSG00000117477",
         "ENSG00000117505",
         "ENSG00000117519",
+        "ENSG00000117525",
         "ENSG00000117560",
         "ENSG00000117594",
         "ENSG00000117632",
@@ -957,7 +948,6 @@
         "ENSG00000118271",
         "ENSG00000118402",
         "ENSG00000118407",
-        "ENSG00000118473",
         "ENSG00000118496",
         "ENSG00000118503",
         "ENSG00000118514",
@@ -1066,12 +1056,12 @@
         "ENSG00000123119",
         "ENSG00000123124",
         "ENSG00000123154",
-        "ENSG00000123240",
         "ENSG00000123243",
         "ENSG00000123329",
         "ENSG00000123342",
         "ENSG00000123360",
         "ENSG00000123384",
+        "ENSG00000123388",
         "ENSG00000123411",
         "ENSG00000123415",
         "ENSG00000123416",
@@ -1126,13 +1116,13 @@
         "ENSG00000125398",
         "ENSG00000125430",
         "ENSG00000125457",
-        "ENSG00000125484",
+        "ENSG00000125508",
         "ENSG00000125538",
         "ENSG00000125633",
-        "ENSG00000125703",
-        "ENSG00000125733",
+        "ENSG00000125730",
         "ENSG00000125735",
         "ENSG00000125740",
+        "ENSG00000125798",
         "ENSG00000125810",
         "ENSG00000125812",
         "ENSG00000125834",
@@ -1141,6 +1131,7 @@
         "ENSG00000125846",
         "ENSG00000125848",
         "ENSG00000125851",
+        "ENSG00000125863",
         "ENSG00000125868",
         "ENSG00000125871",
         "ENSG00000125910",
@@ -1149,6 +1140,7 @@
         "ENSG00000126001",
         "ENSG00000126016",
         "ENSG00000126106",
+        "ENSG00000126218",
         "ENSG00000126246",
         "ENSG00000126262",
         "ENSG00000126353",
@@ -1158,7 +1150,6 @@
         "ENSG00000126790",
         "ENSG00000126814",
         "ENSG00000126882",
-        "ENSG00000126883",
         "ENSG00000126945",
         "ENSG00000126947",
         "ENSG00000127074",
@@ -1238,7 +1229,6 @@
         "ENSG00000130055",
         "ENSG00000130066",
         "ENSG00000130147",
-        "ENSG00000130176",
         "ENSG00000130203",
         "ENSG00000130270",
         "ENSG00000130294",
@@ -1247,7 +1237,6 @@
         "ENSG00000130347",
         "ENSG00000130508",
         "ENSG00000130513",
-        "ENSG00000130540",
         "ENSG00000130558",
         "ENSG00000130590",
         "ENSG00000130598",
@@ -1258,7 +1247,6 @@
         "ENSG00000130827",
         "ENSG00000130830",
         "ENSG00000130844",
-        "ENSG00000130856",
         "ENSG00000130881",
         "ENSG00000130997",
         "ENSG00000131015",
@@ -1275,7 +1263,6 @@
         "ENSG00000131400",
         "ENSG00000131435",
         "ENSG00000131459",
-        "ENSG00000131471",
         "ENSG00000131480",
         "ENSG00000131482",
         "ENSG00000131634",
@@ -1319,13 +1306,11 @@
         "ENSG00000132613",
         "ENSG00000132639",
         "ENSG00000132664",
-        "ENSG00000132704",
         "ENSG00000132718",
         "ENSG00000132740",
         "ENSG00000132763",
         "ENSG00000132768",
         "ENSG00000132773",
-        "ENSG00000132792",
         "ENSG00000132823",
         "ENSG00000132824",
         "ENSG00000132825",
@@ -1340,7 +1325,6 @@
         "ENSG00000133392",
         "ENSG00000133393",
         "ENSG00000133460",
-        "ENSG00000133475",
         "ENSG00000133477",
         "ENSG00000133561",
         "ENSG00000133574",
@@ -1362,7 +1346,6 @@
         "ENSG00000134201",
         "ENSG00000134202",
         "ENSG00000134240",
-        "ENSG00000134247",
         "ENSG00000134250",
         "ENSG00000134253",
         "ENSG00000134285",
@@ -1452,7 +1435,6 @@
         "ENSG00000136541",
         "ENSG00000136542",
         "ENSG00000136546",
-        "ENSG00000136628",
         "ENSG00000136630",
         "ENSG00000136634",
         "ENSG00000136826",
@@ -1468,7 +1450,6 @@
         "ENSG00000136997",
         "ENSG00000136999",
         "ENSG00000137033",
-        "ENSG00000137040",
         "ENSG00000137078",
         "ENSG00000137094",
         "ENSG00000137101",
@@ -1488,7 +1469,6 @@
         "ENSG00000137501",
         "ENSG00000137502",
         "ENSG00000137507",
-        "ENSG00000137509",
         "ENSG00000137563",
         "ENSG00000137573",
         "ENSG00000137575",
@@ -1549,7 +1529,6 @@
         "ENSG00000138764",
         "ENSG00000138772",
         "ENSG00000138778",
-        "ENSG00000138794",
         "ENSG00000138798",
         "ENSG00000138835",
         "ENSG00000138964",
@@ -1580,7 +1559,6 @@
         "ENSG00000139679",
         "ENSG00000139734",
         "ENSG00000139737",
-        "ENSG00000139832",
         "ENSG00000139874",
         "ENSG00000139910",
         "ENSG00000139926",
@@ -1613,7 +1591,6 @@
         "ENSG00000141034",
         "ENSG00000141040",
         "ENSG00000141052",
-        "ENSG00000141076",
         "ENSG00000141101",
         "ENSG00000141232",
         "ENSG00000141295",
@@ -1634,7 +1611,6 @@
         "ENSG00000141753",
         "ENSG00000141756",
         "ENSG00000141837",
-        "ENSG00000141867",
         "ENSG00000141956",
         "ENSG00000142156",
         "ENSG00000142173",
@@ -1674,7 +1650,6 @@
         "ENSG00000143341",
         "ENSG00000143363",
         "ENSG00000143369",
-        "ENSG00000143373",
         "ENSG00000143376",
         "ENSG00000143382",
         "ENSG00000143387",
@@ -1689,6 +1664,7 @@
         "ENSG00000143622",
         "ENSG00000143653",
         "ENSG00000143727",
+        "ENSG00000143740",
         "ENSG00000143742",
         "ENSG00000143797",
         "ENSG00000143801",
@@ -1696,7 +1672,6 @@
         "ENSG00000143891",
         "ENSG00000143933",
         "ENSG00000143942",
-        "ENSG00000144031",
         "ENSG00000144045",
         "ENSG00000144061",
         "ENSG00000144120",
@@ -1735,6 +1710,7 @@
         "ENSG00000145217",
         "ENSG00000145244",
         "ENSG00000145293",
+        "ENSG00000145321",
         "ENSG00000145335",
         "ENSG00000145362",
         "ENSG00000145365",
@@ -1747,6 +1723,7 @@
         "ENSG00000145700",
         "ENSG00000145725",
         "ENSG00000145824",
+        "ENSG00000145863",
         "ENSG00000145868",
         "ENSG00000145882",
         "ENSG00000145908",
@@ -1770,6 +1747,7 @@
         "ENSG00000146410",
         "ENSG00000146411",
         "ENSG00000146414",
+        "ENSG00000146521",
         "ENSG00000146530",
         "ENSG00000146535",
         "ENSG00000146670",
@@ -1789,9 +1767,7 @@
         "ENSG00000147118",
         "ENSG00000147130",
         "ENSG00000147224",
-        "ENSG00000147255",
         "ENSG00000147257",
-        "ENSG00000147383",
         "ENSG00000147394",
         "ENSG00000147416",
         "ENSG00000147437",
@@ -1804,7 +1780,6 @@
         "ENSG00000147570",
         "ENSG00000147604",
         "ENSG00000147606",
-        "ENSG00000147647",
         "ENSG00000147804",
         "ENSG00000147852",
         "ENSG00000147854",
@@ -1871,7 +1846,6 @@
         "ENSG00000150967",
         "ENSG00000150991",
         "ENSG00000151093",
-        "ENSG00000151116",
         "ENSG00000151117",
         "ENSG00000151176",
         "ENSG00000151338",
@@ -1884,7 +1858,6 @@
         "ENSG00000151790",
         "ENSG00000151806",
         "ENSG00000151849",
-        "ENSG00000151881",
         "ENSG00000151892",
         "ENSG00000151929",
         "ENSG00000152137",
@@ -1922,10 +1895,12 @@
         "ENSG00000153201",
         "ENSG00000153234",
         "ENSG00000153291",
+        "ENSG00000153294",
         "ENSG00000153395",
         "ENSG00000153446",
         "ENSG00000153531",
         "ENSG00000153563",
+        "ENSG00000153790",
         "ENSG00000153820",
         "ENSG00000153885",
         "ENSG00000153896",
@@ -2002,7 +1977,6 @@
         "ENSG00000156795",
         "ENSG00000156853",
         "ENSG00000156885",
-        "ENSG00000156966",
         "ENSG00000156968",
         "ENSG00000156970",
         "ENSG00000156990",
@@ -2035,7 +2009,6 @@
         "ENSG00000157890",
         "ENSG00000158050",
         "ENSG00000158055",
-        "ENSG00000158092",
         "ENSG00000158106",
         "ENSG00000158113",
         "ENSG00000158156",
@@ -2047,11 +2020,9 @@
         "ENSG00000158516",
         "ENSG00000158526",
         "ENSG00000158691",
-        "ENSG00000158711",
         "ENSG00000158764",
         "ENSG00000158773",
         "ENSG00000158806",
-        "ENSG00000158816",
         "ENSG00000158859",
         "ENSG00000158869",
         "ENSG00000158882",
@@ -2063,10 +2034,10 @@
         "ENSG00000159197",
         "ENSG00000159200",
         "ENSG00000159216",
+        "ENSG00000159224",
         "ENSG00000159228",
         "ENSG00000159307",
         "ENSG00000159348",
-        "ENSG00000159374",
         "ENSG00000159388",
         "ENSG00000159403",
         "ENSG00000159423",
@@ -2089,7 +2060,6 @@
         "ENSG00000160182",
         "ENSG00000160183",
         "ENSG00000160185",
-        "ENSG00000160219",
         "ENSG00000160233",
         "ENSG00000160255",
         "ENSG00000160298",
@@ -2129,6 +2099,7 @@
         "ENSG00000161647",
         "ENSG00000161692",
         "ENSG00000161800",
+        "ENSG00000161888",
         "ENSG00000161921",
         "ENSG00000161929",
         "ENSG00000162063",
@@ -2148,15 +2119,12 @@
         "ENSG00000162511",
         "ENSG00000162512",
         "ENSG00000162552",
-        "ENSG00000162572",
         "ENSG00000162595",
         "ENSG00000162600",
         "ENSG00000162607",
-        "ENSG00000162614",
         "ENSG00000162616",
         "ENSG00000162620",
         "ENSG00000162627",
-        "ENSG00000162631",
         "ENSG00000162639",
         "ENSG00000162650",
         "ENSG00000162654",
@@ -2183,7 +2151,6 @@
         "ENSG00000163138",
         "ENSG00000163141",
         "ENSG00000163171",
-        "ENSG00000163257",
         "ENSG00000163288",
         "ENSG00000163291",
         "ENSG00000163312",
@@ -2233,9 +2200,7 @@
         "ENSG00000163795",
         "ENSG00000163803",
         "ENSG00000163815",
-        "ENSG00000163820",
         "ENSG00000163823",
-        "ENSG00000163870",
         "ENSG00000163873",
         "ENSG00000163879",
         "ENSG00000163933",
@@ -2304,17 +2269,18 @@
         "ENSG00000164933",
         "ENSG00000164949",
         "ENSG00000164953",
+        "ENSG00000164972",
         "ENSG00000165028",
         "ENSG00000165029",
         "ENSG00000165030",
         "ENSG00000165072",
         "ENSG00000165092",
-        "ENSG00000165115",
         "ENSG00000165124",
         "ENSG00000165140",
         "ENSG00000165152",
         "ENSG00000165186",
         "ENSG00000165195",
+        "ENSG00000165197",
         "ENSG00000165215",
         "ENSG00000165271",
         "ENSG00000165312",
@@ -2347,13 +2313,11 @@
         "ENSG00000166033",
         "ENSG00000166035",
         "ENSG00000166073",
-        "ENSG00000166086",
         "ENSG00000166123",
         "ENSG00000166133",
         "ENSG00000166147",
         "ENSG00000166165",
         "ENSG00000166173",
-        "ENSG00000166183",
         "ENSG00000166188",
         "ENSG00000166192",
         "ENSG00000166199",
@@ -2392,7 +2356,6 @@
         "ENSG00000166816",
         "ENSG00000166819",
         "ENSG00000166821",
-        "ENSG00000166840",
         "ENSG00000166851",
         "ENSG00000166860",
         "ENSG00000166869",
@@ -2491,7 +2454,6 @@
         "ENSG00000168826",
         "ENSG00000168872",
         "ENSG00000168874",
-        "ENSG00000168883",
         "ENSG00000168890",
         "ENSG00000168907",
         "ENSG00000169018",
@@ -2504,14 +2466,12 @@
         "ENSG00000169122",
         "ENSG00000169129",
         "ENSG00000169131",
-        "ENSG00000169174",
         "ENSG00000169188",
         "ENSG00000169213",
         "ENSG00000169220",
         "ENSG00000169242",
         "ENSG00000169252",
         "ENSG00000169282",
-        "ENSG00000169291",
         "ENSG00000169299",
         "ENSG00000169347",
         "ENSG00000169410",
@@ -2520,7 +2480,6 @@
         "ENSG00000169429",
         "ENSG00000169432",
         "ENSG00000169439",
-        "ENSG00000169442",
         "ENSG00000169507",
         "ENSG00000169508",
         "ENSG00000169554",
@@ -2541,7 +2500,6 @@
         "ENSG00000169902",
         "ENSG00000169903",
         "ENSG00000169908",
-        "ENSG00000169914",
         "ENSG00000169951",
         "ENSG00000169955",
         "ENSG00000169962",
@@ -2563,6 +2521,7 @@
         "ENSG00000170381",
         "ENSG00000170382",
         "ENSG00000170421",
+        "ENSG00000170439",
         "ENSG00000170445",
         "ENSG00000170458",
         "ENSG00000170464",
@@ -2586,10 +2545,7 @@
         "ENSG00000171224",
         "ENSG00000171236",
         "ENSG00000171303",
-        "ENSG00000171307",
         "ENSG00000171345",
-        "ENSG00000171443",
-        "ENSG00000171444",
         "ENSG00000171448",
         "ENSG00000171451",
         "ENSG00000171453",
@@ -2614,7 +2570,6 @@
         "ENSG00000172123",
         "ENSG00000172164",
         "ENSG00000172167",
-        "ENSG00000172171",
         "ENSG00000172209",
         "ENSG00000172215",
         "ENSG00000172236",
@@ -2641,7 +2596,6 @@
         "ENSG00000172738",
         "ENSG00000172771",
         "ENSG00000172794",
-        "ENSG00000172824",
         "ENSG00000172831",
         "ENSG00000172840",
         "ENSG00000172867",
@@ -2657,12 +2611,12 @@
         "ENSG00000173080",
         "ENSG00000173110",
         "ENSG00000173114",
+        "ENSG00000173157",
         "ENSG00000173198",
         "ENSG00000173208",
         "ENSG00000173218",
         "ENSG00000173227",
         "ENSG00000173237",
-        "ENSG00000173261",
         "ENSG00000173267",
         "ENSG00000173269",
         "ENSG00000173275",
@@ -2682,11 +2636,11 @@
         "ENSG00000173809",
         "ENSG00000173825",
         "ENSG00000173918",
+        "ENSG00000173947",
         "ENSG00000173950",
         "ENSG00000174007",
         "ENSG00000174032",
         "ENSG00000174059",
-        "ENSG00000174080",
         "ENSG00000174099",
         "ENSG00000174125",
         "ENSG00000174130",
@@ -2704,6 +2658,7 @@
         "ENSG00000174483",
         "ENSG00000174500",
         "ENSG00000174514",
+        "ENSG00000174562",
         "ENSG00000174564",
         "ENSG00000174600",
         "ENSG00000174684",
@@ -2716,7 +2671,6 @@
         "ENSG00000174807",
         "ENSG00000174837",
         "ENSG00000174840",
-        "ENSG00000174844",
         "ENSG00000174915",
         "ENSG00000174946",
         "ENSG00000174951",
@@ -2755,7 +2709,6 @@
         "ENSG00000175874",
         "ENSG00000175899",
         "ENSG00000175906",
-        "ENSG00000175967",
         "ENSG00000175970",
         "ENSG00000176014",
         "ENSG00000176018",
@@ -2774,7 +2727,6 @@
         "ENSG00000176788",
         "ENSG00000176840",
         "ENSG00000176884",
-        "ENSG00000176896",
         "ENSG00000176907",
         "ENSG00000176928",
         "ENSG00000176953",
@@ -2815,9 +2767,7 @@
         "ENSG00000177888",
         "ENSG00000177917",
         "ENSG00000177932",
-        "ENSG00000177943",
         "ENSG00000177946",
-        "ENSG00000177963",
         "ENSG00000177981",
         "ENSG00000177984",
         "ENSG00000178026",
@@ -2835,7 +2785,6 @@
         "ENSG00000178462",
         "ENSG00000178498",
         "ENSG00000178538",
-        "ENSG00000178562",
         "ENSG00000178567",
         "ENSG00000178665",
         "ENSG00000178685",
@@ -2853,7 +2802,6 @@
         "ENSG00000178997",
         "ENSG00000178999",
         "ENSG00000179021",
-        "ENSG00000179051",
         "ENSG00000179144",
         "ENSG00000179148",
         "ENSG00000179152",
@@ -2864,7 +2812,6 @@
         "ENSG00000179388",
         "ENSG00000179476",
         "ENSG00000179520",
-        "ENSG00000179523",
         "ENSG00000179528",
         "ENSG00000179542",
         "ENSG00000179598",
@@ -2877,11 +2824,11 @@
         "ENSG00000179915",
         "ENSG00000179941",
         "ENSG00000179988",
+        "ENSG00000180066",
         "ENSG00000180071",
         "ENSG00000180185",
         "ENSG00000180257",
         "ENSG00000180329",
-        "ENSG00000180346",
         "ENSG00000180347",
         "ENSG00000180353",
         "ENSG00000180423",
@@ -2896,6 +2843,7 @@
         "ENSG00000180644",
         "ENSG00000180667",
         "ENSG00000180694",
+        "ENSG00000180720",
         "ENSG00000180767",
         "ENSG00000180777",
         "ENSG00000180801",
@@ -2910,6 +2858,7 @@
         "ENSG00000181045",
         "ENSG00000181135",
         "ENSG00000181163",
+        "ENSG00000181171",
         "ENSG00000181191",
         "ENSG00000181192",
         "ENSG00000181234",
@@ -2958,7 +2907,6 @@
         "ENSG00000182568",
         "ENSG00000182578",
         "ENSG00000182612",
-        "ENSG00000182636",
         "ENSG00000182700",
         "ENSG00000182718",
         "ENSG00000182809",
@@ -2966,6 +2914,7 @@
         "ENSG00000182853",
         "ENSG00000182866",
         "ENSG00000182902",
+        "ENSG00000182950",
         "ENSG00000182963",
         "ENSG00000182983",
         "ENSG00000182985",
@@ -2977,6 +2926,7 @@
         "ENSG00000183150",
         "ENSG00000183258",
         "ENSG00000183273",
+        "ENSG00000183287",
         "ENSG00000183386",
         "ENSG00000183431",
         "ENSG00000183439",
@@ -3014,6 +2964,7 @@
         "ENSG00000184371",
         "ENSG00000184378",
         "ENSG00000184428",
+        "ENSG00000184441",
         "ENSG00000184445",
         "ENSG00000184459",
         "ENSG00000184489",
@@ -3038,7 +2989,9 @@
         "ENSG00000184956",
         "ENSG00000184979",
         "ENSG00000185002",
+        "ENSG00000185010",
         "ENSG00000185022",
+        "ENSG00000185038",
         "ENSG00000185065",
         "ENSG00000185085",
         "ENSG00000185090",
@@ -3060,7 +3013,6 @@
         "ENSG00000185650",
         "ENSG00000185652",
         "ENSG00000185668",
-        "ENSG00000185674",
         "ENSG00000185736",
         "ENSG00000185745",
         "ENSG00000185761",
@@ -3077,7 +3029,6 @@
         "ENSG00000186049",
         "ENSG00000186056",
         "ENSG00000186188",
-        "ENSG00000186193",
         "ENSG00000186265",
         "ENSG00000186272",
         "ENSG00000186283",
@@ -3103,6 +3054,7 @@
         "ENSG00000186818",
         "ENSG00000186854",
         "ENSG00000186889",
+        "ENSG00000187048",
         "ENSG00000187068",
         "ENSG00000187094",
         "ENSG00000187098",
@@ -3136,6 +3088,7 @@
         "ENSG00000187808",
         "ENSG00000187815",
         "ENSG00000187860",
+        "ENSG00000187889",
         "ENSG00000187908",
         "ENSG00000187942",
         "ENSG00000187955",
@@ -3146,6 +3099,7 @@
         "ENSG00000188042",
         "ENSG00000188060",
         "ENSG00000188070",
+        "ENSG00000188163",
         "ENSG00000188167",
         "ENSG00000188175",
         "ENSG00000188185",
@@ -3153,7 +3107,6 @@
         "ENSG00000188229",
         "ENSG00000188257",
         "ENSG00000188282",
-        "ENSG00000188295",
         "ENSG00000188305",
         "ENSG00000188315",
         "ENSG00000188321",
@@ -3167,6 +3120,7 @@
         "ENSG00000188536",
         "ENSG00000188549",
         "ENSG00000188613",
+        "ENSG00000188620",
         "ENSG00000188643",
         "ENSG00000188659",
         "ENSG00000188687",
@@ -3225,20 +3179,18 @@
         "ENSG00000196388",
         "ENSG00000196391",
         "ENSG00000196411",
-        "ENSG00000196455",
         "ENSG00000196459",
         "ENSG00000196466",
         "ENSG00000196497",
-        "ENSG00000196505",
         "ENSG00000196569",
         "ENSG00000196576",
         "ENSG00000196581",
         "ENSG00000196584",
         "ENSG00000196611",
         "ENSG00000196616",
-        "ENSG00000196620",
         "ENSG00000196632",
         "ENSG00000196653",
+        "ENSG00000196659",
         "ENSG00000196670",
         "ENSG00000196711",
         "ENSG00000196741",
@@ -3256,7 +3208,6 @@
         "ENSG00000197054",
         "ENSG00000197062",
         "ENSG00000197093",
-        "ENSG00000197102",
         "ENSG00000197119",
         "ENSG00000197121",
         "ENSG00000197140",
@@ -3271,7 +3222,6 @@
         "ENSG00000197279",
         "ENSG00000197291",
         "ENSG00000197299",
-        "ENSG00000197301",
         "ENSG00000197329",
         "ENSG00000197355",
         "ENSG00000197372",
@@ -3282,6 +3232,7 @@
         "ENSG00000197506",
         "ENSG00000197520",
         "ENSG00000197535",
+        "ENSG00000197557",
         "ENSG00000197566",
         "ENSG00000197576",
         "ENSG00000197580",
@@ -3308,7 +3259,6 @@
         "ENSG00000197888",
         "ENSG00000197921",
         "ENSG00000197933",
-        "ENSG00000197935",
         "ENSG00000197937",
         "ENSG00000197951",
         "ENSG00000198015",
@@ -3342,15 +3292,16 @@
         "ENSG00000198576",
         "ENSG00000198610",
         "ENSG00000198670",
-        "ENSG00000198680",
         "ENSG00000198689",
         "ENSG00000198691",
         "ENSG00000198700",
         "ENSG00000198712",
         "ENSG00000198715",
         "ENSG00000198719",
+        "ENSG00000198723",
         "ENSG00000198727",
         "ENSG00000198732",
+        "ENSG00000198734",
         "ENSG00000198740",
         "ENSG00000198746",
         "ENSG00000198756",
@@ -3360,13 +3311,11 @@
         "ENSG00000198796",
         "ENSG00000198797",
         "ENSG00000198804",
-        "ENSG00000198805",
         "ENSG00000198826",
         "ENSG00000198829",
         "ENSG00000198830",
         "ENSG00000198838",
         "ENSG00000198848",
-        "ENSG00000198883",
         "ENSG00000198885",
         "ENSG00000198886",
         "ENSG00000198890",
@@ -3379,7 +3328,6 @@
         "ENSG00000198948",
         "ENSG00000198952",
         "ENSG00000198963",
-        "ENSG00000203288",
         "ENSG00000203356",
         "ENSG00000203497",
         "ENSG00000203499",
@@ -3391,7 +3339,6 @@
         "ENSG00000203872",
         "ENSG00000204086",
         "ENSG00000204103",
-        "ENSG00000204161",
         "ENSG00000204252",
         "ENSG00000204257",
         "ENSG00000204271",
@@ -3402,7 +3349,6 @@
         "ENSG00000204389",
         "ENSG00000204390",
         "ENSG00000204396",
-        "ENSG00000204420",
         "ENSG00000204421",
         "ENSG00000204472",
         "ENSG00000204516",
@@ -3415,7 +3361,6 @@
         "ENSG00000204616",
         "ENSG00000204618",
         "ENSG00000204713",
-        "ENSG00000204815",
         "ENSG00000204852",
         "ENSG00000204856",
         "ENSG00000204860",
@@ -3441,21 +3386,13 @@
         "ENSG00000205810",
         "ENSG00000205853",
         "ENSG00000205885",
-        "ENSG00000205913",
-        "ENSG00000206052",
+        "ENSG00000205929",
         "ENSG00000206075",
         "ENSG00000206172",
-        "ENSG00000206530",
         "ENSG00000206535",
         "ENSG00000206538",
         "ENSG00000211445",
         "ENSG00000211448",
-        "ENSG00000211677",
-        "ENSG00000211679",
-        "ENSG00000211689",
-        "ENSG00000211695",
-        "ENSG00000211829",
-        "ENSG00000212719",
         "ENSG00000212747",
         "ENSG00000212916",
         "ENSG00000213066",
@@ -3466,7 +3403,6 @@
         "ENSG00000213398",
         "ENSG00000213516",
         "ENSG00000213585",
-        "ENSG00000213588",
         "ENSG00000213626",
         "ENSG00000213672",
         "ENSG00000213694",
@@ -3482,64 +3418,67 @@
         "ENSG00000214106",
         "ENSG00000214114",
         "ENSG00000214146",
-        "ENSG00000214160",
         "ENSG00000214193",
+        "ENSG00000214248",
+        "ENSG00000214415",
         "ENSG00000214456",
         "ENSG00000214548",
         "ENSG00000214575",
         "ENSG00000214814",
         "ENSG00000214827",
         "ENSG00000214870",
-        "ENSG00000215021",
         "ENSG00000215218",
         "ENSG00000215251",
-        "ENSG00000215256",
         "ENSG00000215386",
         "ENSG00000215424",
         "ENSG00000215883",
         "ENSG00000216490",
         "ENSG00000218018",
+        "ENSG00000219073",
         "ENSG00000221829",
         "ENSG00000221890",
         "ENSG00000221916",
         "ENSG00000221923",
         "ENSG00000221946",
         "ENSG00000221949",
-        "ENSG00000221988",
         "ENSG00000221994",
         "ENSG00000222009",
         "ENSG00000222041",
         "ENSG00000222046",
         "ENSG00000223387",
-        "ENSG00000223537",
+        "ENSG00000223522",
         "ENSG00000223546",
         "ENSG00000223715",
         "ENSG00000223734",
         "ENSG00000223776",
         "ENSG00000223799",
         "ENSG00000223806",
-        "ENSG00000223865",
         "ENSG00000223960",
         "ENSG00000224023",
         "ENSG00000224046",
-        "ENSG00000224093",
         "ENSG00000224152",
         "ENSG00000224238",
+        "ENSG00000224272",
         "ENSG00000224358",
         "ENSG00000224397",
         "ENSG00000224424",
-        "ENSG00000224429",
         "ENSG00000224509",
         "ENSG00000224565",
         "ENSG00000224616",
+        "ENSG00000224635",
         "ENSG00000224660",
         "ENSG00000224687",
+        "ENSG00000224738",
         "ENSG00000224805",
+        "ENSG00000224848",
         "ENSG00000224903",
         "ENSG00000224934",
+        "ENSG00000224961",
         "ENSG00000224982",
+        "ENSG00000225032",
         "ENSG00000225177",
         "ENSG00000225265",
+        "ENSG00000225335",
         "ENSG00000225377",
         "ENSG00000225439",
         "ENSG00000225465",
@@ -3557,28 +3496,27 @@
         "ENSG00000226137",
         "ENSG00000226200",
         "ENSG00000226237",
-        "ENSG00000226445",
+        "ENSG00000226690",
         "ENSG00000226711",
         "ENSG00000226763",
         "ENSG00000226779",
         "ENSG00000226791",
-        "ENSG00000226806",
         "ENSG00000226889",
         "ENSG00000227051",
         "ENSG00000227117",
-        "ENSG00000227172",
         "ENSG00000227199",
+        "ENSG00000227218",
         "ENSG00000227354",
-        "ENSG00000227492",
         "ENSG00000227502",
+        "ENSG00000227540",
+        "ENSG00000228037",
+        "ENSG00000228172",
         "ENSG00000228253",
+        "ENSG00000228274",
         "ENSG00000228293",
         "ENSG00000228506",
         "ENSG00000228594",
-        "ENSG00000228661",
         "ENSG00000228784",
-        "ENSG00000228878",
-        "ENSG00000228980",
         "ENSG00000229043",
         "ENSG00000229056",
         "ENSG00000229111",
@@ -3587,9 +3525,9 @@
         "ENSG00000229236",
         "ENSG00000229589",
         "ENSG00000230091",
-        "ENSG00000230215",
         "ENSG00000230366",
         "ENSG00000230438",
+        "ENSG00000230709",
         "ENSG00000230797",
         "ENSG00000230844",
         "ENSG00000230943",
@@ -3600,35 +3538,39 @@
         "ENSG00000231651",
         "ENSG00000231690",
         "ENSG00000231742",
+        "ENSG00000231769",
         "ENSG00000231770",
         "ENSG00000231890",
         "ENSG00000231908",
         "ENSG00000231999",
-        "ENSG00000232564",
+        "ENSG00000232063",
+        "ENSG00000232347",
         "ENSG00000232591",
+        "ENSG00000232611",
         "ENSG00000232613",
         "ENSG00000232650",
         "ENSG00000232656",
         "ENSG00000232677",
         "ENSG00000232684",
-        "ENSG00000232756",
         "ENSG00000232803",
         "ENSG00000232810",
+        "ENSG00000232811",
         "ENSG00000232912",
         "ENSG00000233070",
         "ENSG00000233101",
         "ENSG00000233175",
-        "ENSG00000233184",
         "ENSG00000233220",
-        "ENSG00000233246",
+        "ENSG00000233223",
         "ENSG00000233334",
         "ENSG00000233436",
         "ENSG00000233554",
         "ENSG00000233608",
         "ENSG00000233695",
+        "ENSG00000233785",
         "ENSG00000233791",
         "ENSG00000234028",
         "ENSG00000234076",
+        "ENSG00000234147",
         "ENSG00000234171",
         "ENSG00000234184",
         "ENSG00000234284",
@@ -3647,14 +3589,12 @@
         "ENSG00000235106",
         "ENSG00000235162",
         "ENSG00000235173",
-        "ENSG00000235300",
         "ENSG00000235488",
         "ENSG00000235531",
         "ENSG00000235560",
         "ENSG00000235568",
         "ENSG00000235597",
         "ENSG00000235706",
-        "ENSG00000235731",
         "ENSG00000235740",
         "ENSG00000235770",
         "ENSG00000235865",
@@ -3663,18 +3603,21 @@
         "ENSG00000236104",
         "ENSG00000236144",
         "ENSG00000236200",
+        "ENSG00000236266",
         "ENSG00000236287",
         "ENSG00000236384",
         "ENSG00000236526",
         "ENSG00000236671",
-        "ENSG00000236795",
         "ENSG00000236849",
         "ENSG00000236882",
+        "ENSG00000236924",
         "ENSG00000237036",
         "ENSG00000237054",
+        "ENSG00000237126",
         "ENSG00000237172",
         "ENSG00000237181",
         "ENSG00000237187",
+        "ENSG00000237301",
         "ENSG00000237399",
         "ENSG00000237424",
         "ENSG00000237440",
@@ -3688,11 +3631,12 @@
         "ENSG00000238198",
         "ENSG00000239219",
         "ENSG00000239282",
+        "ENSG00000239407",
         "ENSG00000239453",
         "ENSG00000239523",
         "ENSG00000239697",
         "ENSG00000239887",
-        "ENSG00000240063",
+        "ENSG00000240045",
         "ENSG00000240204",
         "ENSG00000240211",
         "ENSG00000240288",
@@ -3704,30 +3648,28 @@
         "ENSG00000240889",
         "ENSG00000241163",
         "ENSG00000241316",
-        "ENSG00000241322",
         "ENSG00000241484",
         "ENSG00000241560",
         "ENSG00000241644",
         "ENSG00000241684",
-        "ENSG00000241769",
-        "ENSG00000241839",
         "ENSG00000241852",
         "ENSG00000242110",
         "ENSG00000242258",
         "ENSG00000242474",
+        "ENSG00000242553",
         "ENSG00000242732",
         "ENSG00000242767",
-        "ENSG00000242781",
         "ENSG00000243083",
         "ENSG00000243479",
         "ENSG00000243566",
         "ENSG00000243710",
         "ENSG00000243955",
-        "ENSG00000244038",
         "ENSG00000244041",
         "ENSG00000244067",
         "ENSG00000244242",
+        "ENSG00000244342",
         "ENSG00000244405",
+        "ENSG00000244459",
         "ENSG00000244486",
         "ENSG00000244509",
         "ENSG00000244734",
@@ -3741,17 +3683,16 @@
         "ENSG00000245680",
         "ENSG00000245975",
         "ENSG00000246089",
-        "ENSG00000246214",
         "ENSG00000246223",
+        "ENSG00000246308",
         "ENSG00000246334",
         "ENSG00000246366",
-        "ENSG00000246379",
         "ENSG00000246695",
         "ENSG00000246859",
         "ENSG00000246898",
         "ENSG00000247081",
+        "ENSG00000247134",
         "ENSG00000247572",
-        "ENSG00000247624",
         "ENSG00000247626",
         "ENSG00000247675",
         "ENSG00000247735",
@@ -3760,14 +3701,16 @@
         "ENSG00000247982",
         "ENSG00000248008",
         "ENSG00000248049",
+        "ENSG00000248144",
         "ENSG00000248174",
         "ENSG00000248429",
-        "ENSG00000248554",
+        "ENSG00000248712",
         "ENSG00000248727",
         "ENSG00000248810",
         "ENSG00000249096",
         "ENSG00000249241",
         "ENSG00000249242",
+        "ENSG00000249359",
         "ENSG00000249395",
         "ENSG00000249471",
         "ENSG00000249786",
@@ -3775,45 +3718,46 @@
         "ENSG00000249992",
         "ENSG00000250073",
         "ENSG00000250116",
+        "ENSG00000250132",
+        "ENSG00000250240",
         "ENSG00000250331",
+        "ENSG00000250397",
         "ENSG00000250548",
         "ENSG00000250742",
-        "ENSG00000250891",
-        "ENSG00000250910",
+        "ENSG00000250999",
         "ENSG00000251022",
         "ENSG00000251075",
+        "ENSG00000251143",
         "ENSG00000251230",
-        "ENSG00000251247",
         "ENSG00000251279",
         "ENSG00000251369",
         "ENSG00000251586",
+        "ENSG00000251615",
+        "ENSG00000253106",
         "ENSG00000253133",
+        "ENSG00000253214",
         "ENSG00000253250",
         "ENSG00000253408",
         "ENSG00000253549",
         "ENSG00000253598",
         "ENSG00000253633",
-        "ENSG00000253641",
         "ENSG00000253686",
         "ENSG00000253716",
         "ENSG00000253846",
         "ENSG00000253958",
         "ENSG00000253982",
-        "ENSG00000254003",
         "ENSG00000254211",
         "ENSG00000254415",
+        "ENSG00000254427",
         "ENSG00000254469",
-        "ENSG00000254554",
         "ENSG00000254685",
         "ENSG00000254815",
-        "ENSG00000254854",
         "ENSG00000255008",
         "ENSG00000255153",
         "ENSG00000255197",
         "ENSG00000255423",
         "ENSG00000255561",
         "ENSG00000255690",
-        "ENSG00000255992",
         "ENSG00000256039",
         "ENSG00000256043",
         "ENSG00000256087",
@@ -3821,66 +3765,90 @@
         "ENSG00000256235",
         "ENSG00000256269",
         "ENSG00000256294",
+        "ENSG00000256433",
         "ENSG00000256771",
         "ENSG00000256862",
         "ENSG00000257093",
         "ENSG00000257097",
         "ENSG00000257167",
+        "ENSG00000257259",
+        "ENSG00000257279",
         "ENSG00000257285",
         "ENSG00000257702",
         "ENSG00000258038",
         "ENSG00000258056",
         "ENSG00000258279",
+        "ENSG00000258302",
         "ENSG00000258366",
         "ENSG00000258457",
         "ENSG00000258476",
         "ENSG00000258484",
         "ENSG00000258498",
         "ENSG00000258537",
-        "ENSG00000258545",
-        "ENSG00000258730",
         "ENSG00000258731",
+        "ENSG00000258752",
+        "ENSG00000258777",
+        "ENSG00000258944",
         "ENSG00000258947",
         "ENSG00000259065",
+        "ENSG00000259134",
         "ENSG00000259153",
         "ENSG00000259172",
         "ENSG00000259207",
         "ENSG00000259319",
         "ENSG00000259330",
         "ENSG00000259343",
+        "ENSG00000259345",
+        "ENSG00000259370",
+        "ENSG00000259407",
         "ENSG00000259431",
         "ENSG00000259488",
         "ENSG00000259577",
         "ENSG00000259583",
         "ENSG00000259642",
-        "ENSG00000259788",
         "ENSG00000259818",
         "ENSG00000259826",
         "ENSG00000259883",
+        "ENSG00000259891",
+        "ENSG00000259915",
         "ENSG00000259943",
+        "ENSG00000259959",
+        "ENSG00000259974",
+        "ENSG00000259985",
+        "ENSG00000260000",
         "ENSG00000260001",
+        "ENSG00000260060",
+        "ENSG00000260077",
         "ENSG00000260093",
         "ENSG00000260219",
         "ENSG00000260236",
+        "ENSG00000260267",
+        "ENSG00000260273",
         "ENSG00000260278",
         "ENSG00000260285",
         "ENSG00000260314",
         "ENSG00000260329",
         "ENSG00000260339",
+        "ENSG00000260367",
         "ENSG00000260456",
         "ENSG00000260475",
-        "ENSG00000260519",
+        "ENSG00000260495",
+        "ENSG00000260517",
         "ENSG00000260526",
+        "ENSG00000260563",
         "ENSG00000260625",
+        "ENSG00000260733",
         "ENSG00000260806",
         "ENSG00000260807",
         "ENSG00000260852",
         "ENSG00000260876",
         "ENSG00000260886",
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