---
license: mit
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# hep

HepClock is a hepatocyte-specific chronological-age clock trained by lasso on hepatocyte age-DMCTs identified with CellDMC after estimating five liver cell fractions.

| | |
|---|---|
| **Predicts** | chronological age |
| **Species** | Homo sapiens |
| **Tissue** | liver |
| **Data type** | DNA methylation |
| **Model type** | LASSO regression |
| **Year** | 2024 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["hep"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Tong, Huige, et al. "Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution." Aging 16 (2024): 14204–14237.

https://doi.org/10.18632/aging.206184