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README.md
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## 🧠 Model Summary
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A linear PCA model for brain structure T1 MRIs. The models takes in a 3d MRI NIfTI file and compresses to 1200 latent dimensions before reconstructing the image.
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# Training data
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[
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# Example usage
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```
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# get
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git clone https://huggingface.co/radiata-ai/
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cd
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# set up virtual environemt
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python3 -m venv
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source
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# install Python libraries
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pip install -r requirements.txt
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# create the csv file inputs.csv listing the scan paths and other info
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# this script loads the radiata-ai/brain-structure dataset
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python create_csv.py
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mkdir
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mkdir
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# train the model
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nohup python
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```
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# Methods
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lr: float = 1e-4,
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# References
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Puglisi
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Pinaya
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# Citation
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```
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@
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author = {Jesse Brown and Clayton Young},
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title = {
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year = {2025},
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url
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note = {Version 1.0},
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publisher
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}
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```
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# License
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Copyright
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IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
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FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
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AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
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LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
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OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
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SOFTWARE.
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---
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## 🧠 Model Summary
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# brain2vec_PCA
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A linear PCA model for brain structure T1 MRIs. The models takes in a 3d MRI NIfTI file and compresses to 1200 latent dimensions before reconstructing the image.
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# Training data
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[radiata-ai/brain-structure](https://huggingface.co/datasets/radiata-ai/brain-structure): 3066 scans from 2085 individuals in the 'train' split. Mean age = 45.1 +- 24.5, including 2847 scans from cognitively normal subjects and 219 scans from individuals with an Alzheimer's disease clinical diagnosis.
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# Example usage
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```
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# get brain2vec_PCA model repository
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git clone https://huggingface.co/radiata-ai/brain2vec_PCA
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cd brain2vec_PCA
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# set up virtual environemt
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python3 -m venv venv_brain2vec_PCA
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source venv_brain2vec_PCA/bin/activate
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# install Python libraries
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pip install -r requirements.txt
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# create the csv file inputs.csv listing the scan paths and other info
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# this script loads the radiata-ai/brain-structure dataset from Hugging Face
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python create_csv.py
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mkdir pca_cache
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mkdir pca_output
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# train the model
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nohup python train_brain2vec_PCA.py --inputs_csv inputs.csv --output_dir ./pca_output --pca_type standard --n_components 1200 > train_log.txt 2>&1 &
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# model inference
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python inference_brain2vec_PCA.py \
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--pca_model /path/to/pca_model.joblib \
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--input_images /path/to/img1.nii.gz /path/to/img2.nii.gz \
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--output_dir /path/to/out
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# or if you have a CSV with image paths:
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python inference_brain2vec_PCA.py \
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--pca_model /path/to/pca_model.joblib \
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--csv_input /path/to/images.csv \
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--output_dir /path/to/out
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```
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# Methods
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Input scan image dimensions are 113x137x113, 1.5mm^3 resolution, aligned to MNI152 space (see [radiata-ai/brain-structure](https://huggingface.co/datasets/radiata-ai/brain-structure)).
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The image transform crops to 80 x 96 x 80, 2mm^3 resolution, and scales image intensity to range [0,1].
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PCA is performed using [sklearn.decomposition.PCA](https://scikit-learn.org/stable/modules/generated/sklearn.decomposition.PCA.html).
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# Citation
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```
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@misc{Radiata-Brain2Vec-PCA,
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author = {Jesse Brown and Clayton Young},
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title = {brain2vec_PCA: A Linear PCA Model for Brain Structure T1 MRIs},
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year = {2025},
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url = {https://huggingface.co/radiata-ai/brain2vec_PCA},
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note = {Version 1.0},
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publisher = {Hugging Face}
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}
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```
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# License
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### Apache License 2.0
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Copyright 2025 Jesse Brown
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Licensed under the Apache License, Version 2.0 (the "License");
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you may not use this file except in compliance with the License.
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You may obtain a copy of the License at:
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[http://www.apache.org/licenses/LICENSE-2.0](http://www.apache.org/licenses/LICENSE-2.0)
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Unless required by applicable law or agreed to in writing, software
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distributed under the License is distributed on an "AS IS" BASIS,
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WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
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See the License for the specific language governing permissions and
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limitations under the License.
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