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---
title: README
emoji: π
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# Hi, there is [Liang's Lab](https://ins.sjtu.edu.cn/people/lhong/index.html) π
Research on protein-directed modification and redesign based on artificial intelligence technology.
The research content includes but is not limited to protein structure prediction and optimization, protein-directed modification, and design.
## π Recent Papers
- [VenusFactory: An Integrated System for Protein Engineering with Data Retrieval and Language Model Fine-Tuning](https://aclanthology.org/2025.acl-demo.23/). *ACL Demo*, 2025.
- [From high-throughput evaluation to wet-lab studies: advancing mutation effect prediction with a retrieval-enhanced model](https://academic.oup.com/bioinformatics/article/41/Supplement_1/i401/8199374?login=false). *ISMB/ECCB*, 2025.
- [Immunogenicity Prediction with Dual Attention Enables Vaccine Target Selection](https://openreview.net/forum?id=hWmwL9gizZ). *ICLR*, 2025.
- [VenusMutHub: A systematic evaluation of protein mutation effect predictors on small-scale experimental data](https://www.sciencedirect.com/science/article/pii/S2211383525001650). *Acta Pharmaceutica Sinica B*, 2025.
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