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Parent(s): 96bbf4c
update
Browse files- README.md +108 -12
- app.py +13 -4
- config.py +2 -2
- pipeline/thyroid_pipeline.py +3 -3
README.md
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---
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---
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-
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# Thyroid Nodule Analysis Pipeline
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An automated pipeline for thyroid nodule analysis in ultrasound images, covering detection, segmentation, malignancy classification, and ACR TI-RADS risk scoring, all in a single inference flow through a web interface.
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---
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## What it does
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Given one or more thyroid ultrasound images, the system runs four sequential steps:
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1. **Detection** - localises nodules with bounding boxes (YOLOv8s)
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2. **Segmentation** - produces a pixel-level mask of each nodule (UNet++ with SCSE attention)
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3. **Malignancy classification** - estimates benign/malignant probability with a Grad-CAM visual explanation (ResNet50)
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4. **TI-RADS scoring** - assigns an ACR TI-RADS category (TR1–TR5) from 25 radiomic descriptors (Random Forest)
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When multiple images of the same patient are uploaded, the results are automatically aggregated at patient level.
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> **Note:** Results are intended as decision support for a specialist and do not replace clinical judgement.
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---
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## Project structure
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```
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thyroid-pipeline/
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├── models/ # Trained model weights
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│ ├── yolo_finetuned_thyroidxl.pt
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│ ├── best_unet_finetuned.pth
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│ ├── resnet50_finetuned_thyroidxl.pth
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│ ├── best_model_expB_RandomForest.pkl
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│ └── train_features_patient_level_unetmask.csv
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│
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├── pipeline/
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│ ├── detector.py # YOLOv8s nodule detection
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│ ├── segmentor.py # UNet++ pixel-level segmentation
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│ ├── classifier.py # ResNet50 malignancy classification + Grad-CAM
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│ ├── feature_extractor.py # 25 radiomic descriptors
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│ ├── tirads_scorer.py # Random Forest TI-RADS scoring (TR1–TR5)
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│ └── aggregator.py # Patient-level aggregation
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│
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├── utils/
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│ └── visualization.py # Detection and segmentation overlays
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│
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├── app.py # Gradio web interface
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├── config.py # Paths, thresholds, TI-RADS lookup tables
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├── thyroid_pipeline.py # Main pipeline orchestrator
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└── requirements.txt
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```
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---
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## Installation
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**Requirements:** Python 3.10+, and a CUDA-capable GPU (recommended) or CPU.
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```bash
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# Clone the repository
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git clone <repo-url>
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cd thyroid-pipeline
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# Create and activate a virtual environment
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python -m venv venv
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# Windows:
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venv\Scripts\activate
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# Linux / macOS:
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source venv/bin/activate
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# Install dependencies
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pip install -r requirements.txt
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```
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Download the model weights and place them in the `models/` folder.
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---
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## Running the app
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```bash
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python app.py
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```
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The interface will be available at `http://localhost:7860`.
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The app is also deployed on Hugging Face Spaces: https://huggingface.co/spaces/Ale22M/thyroid-pipeline and can be used without any local setup.
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---
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## Usage
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**Single image mode** — upload one `.png` / `.jpg` / `.jpeg` ultrasound image and click *Analyze*. The interface returns:
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- Detection overlay (bounding box)
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- Segmentation overlay (nodule mask)
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- Nodule crop fed to the classifier
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- Grad-CAM heatmap
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- Malignancy probability and label
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- Top radiomic features
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**Patient mode** - upload multiple images of the same patient. In addition to per-image results, the system aggregates everything at patient level and returns a final malignancy classification and an ACR TI-RADS category with the corresponding biopsy recommendation.
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---
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## Dependencies
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ultralytics -> YOLOv8 detection
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segmentation-models-pytorch -> UNet++ with pretrained encoders
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grad-cam -> Grad-CAM explanations
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scikit-learn -> Random Forest TI-RADS classifier
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scikit-image, scipy, opencv-python -> radiomic feature extraction
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gradio -> web interface
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Full pinned versions are in requirements.txt.
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app.py
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feature aggregation.
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File validation:
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Only images are accepted (.png, .jpg, .jpeg
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Invalid formats produce a clear error message before any model inference.
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Partial-failure handling:
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# ZeroGPU
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_ON_HF = os.environ.get("SPACE_ID") is not None
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if _ON_HF:
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import spaces
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import time
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import numpy as np
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border-top: none !important;
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padding-top: 4px !important;
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}
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"""
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with gr.Blocks(title="Thyroid Nodule Analysis Pipeline") as demo:
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input_files = gr.File(
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label = "Upload ultrasound image(s) - single image or multiple views of the same patient",
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file_count = "multiple",
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file_types = [".png", ".jpg", ".jpeg"
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elem_id = "file-upload-box",
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)
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run_btn = gr.Button("Analyze", variant="primary", size="lg")
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label = "Pipeline outputs",
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show_label = True,
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columns = 5,
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height =
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object_fit = "contain",
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)
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gr.Markdown("---")
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feature aggregation.
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File validation:
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Only images are accepted (.png, .jpg, .jpeg).
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Invalid formats produce a clear error message before any model inference.
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Partial-failure handling:
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# ZeroGPU
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_ON_HF = os.environ.get("SPACE_ID") is not None
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if _ON_HF:
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import spaces # type: ignore
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import time
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import numpy as np
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border-top: none !important;
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padding-top: 4px !important;
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}
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#gallery-no-scroll,
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#gallery-no-scroll .grid-wrap,
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#gallery-no-scroll .grid-container {
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max-height: none !important;
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height: auto !important;
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overflow: visible !important;
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}
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"""
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with gr.Blocks(title="Thyroid Nodule Analysis Pipeline") as demo:
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input_files = gr.File(
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label = "Upload ultrasound image(s) - single image or multiple views of the same patient",
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file_count = "multiple",
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file_types = [".png", ".jpg", ".jpeg"],
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elem_id = "file-upload-box",
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)
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run_btn = gr.Button("Analyze", variant="primary", size="lg")
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label = "Pipeline outputs",
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show_label = True,
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columns = 5,
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height = "auto",
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object_fit = "contain",
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elem_id = "gallery-no-scroll",
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)
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gr.Markdown("---")
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config.py
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}
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# Accepted image formats for upload validation
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ACCEPTED_EXTENSIONS = {".png", ".jpg", ".jpeg"
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ACCEPTED_MIME_TYPES = {"image/png", "image/jpeg"
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}
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# Accepted image formats for upload validation
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ACCEPTED_EXTENSIONS = {".png", ".jpg", ".jpeg"}
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ACCEPTED_MIME_TYPES = {"image/png", "image/jpeg"}
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pipeline/thyroid_pipeline.py
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result.label = label
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result.image_crop = Image.fromarray(crop_rgb)
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result.image_gradcam = Image.fromarray(cam_img)
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print(f"[Pipeline] ResNet50
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# Update detection overlay with classification colour
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result.image_detection = Image.fromarray(
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feats_list : list[dict] = []
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for idx, pil_img in enumerate(images_pil):
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print(f"[ThyroidPipeline]
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res = self._process_single(pil_img)
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per_image_results.append(res)
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patient.tirads_class = tr_class
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patient.tirads_risk = self.scorer.get_risk_label(tr_class)
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patient.fnab_recommendation = self.scorer.get_fnab_recommendation(tr_class)
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print(f"[ThyroidPipeline] Patient TI-RADS
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patient.elapsed_total_s = time.perf_counter() - t0
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print(f"[ThyroidPipeline] Patient session done in "
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result.label = label
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result.image_crop = Image.fromarray(crop_rgb)
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result.image_gradcam = Image.fromarray(cam_img)
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print(f"[Pipeline] ResNet50 -> {label} (p={prob_malign:.3f})")
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# Update detection overlay with classification colour
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result.image_detection = Image.fromarray(
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feats_list : list[dict] = []
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for idx, pil_img in enumerate(images_pil):
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print(f"[ThyroidPipeline] - Image {idx + 1}/{len(images_pil)}")
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res = self._process_single(pil_img)
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per_image_results.append(res)
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patient.tirads_class = tr_class
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patient.tirads_risk = self.scorer.get_risk_label(tr_class)
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patient.fnab_recommendation = self.scorer.get_fnab_recommendation(tr_class)
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print(f"[ThyroidPipeline] Patient TI-RADS -> TR{tr_class}")
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patient.elapsed_total_s = time.perf_counter() - t0
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print(f"[ThyroidPipeline] Patient session done in "
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