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import numpy as np
import cv2
import os
import __main__
try:
import mne
from mne.minimum_norm import make_inverse_operator, apply_inverse_raw
MNE_AVAILABLE = True
except ImportError:
MNE_AVAILABLE = False
try:
BaseNode = __main__.BaseNode
except AttributeError:
class BaseNode:
def __init__(self): self.inputs={}; self.outputs={}
class BiophysicalSourceNode(BaseNode):
NODE_TITLE = "Biophysical Source (The Hard Core)"
NODE_CATEGORY = "Science"
def __init__(self):
super().__init__()
self.inputs = {
'gain': 'float', # Signal amplification
'dendritic_thresh': 'float' # Nonlinearity threshold (89629-v2)
}
self.outputs = {
'source_cortex': 'image', # 3D Render of the brain
'structural_modes': 'image', # The Raj Riverbed
'active_dendrites': 'spectrum', # The "Explosion" Stream
'eigenmode_energy': 'spectrum' # Structural alignment
}
# --- 1. THE SERIOUS MNE SETUP (From your file) ---
self.edf_path = r"E:\DocsHouse\450\2.edf" # Hardcoded for serious persistence
self.fs = 160.0
self.is_ready = False
# MNE Objects
self.raw = None
self.inverse_operator = None
self.src = None
self.labels = None
# Raj et al. Structure (Graph Laplacian of the Mesh)
self.mesh_laplacian = None
self.eigenvalues = None
self.eigenvectors = None
# Real-time State
self.current_idx = 0
self.window_size = 32 # Short window for low latency
# Dendritic State (Li et al. 2019)
self.dendritic_potential = np.zeros(68) # 68 Desikan Regions
def setup(self):
if not MNE_AVAILABLE: return
print("[Biophysics] Initializing Serious MNE Pipeline...")
# A. Load Data
self.raw = mne.io.read_raw_edf(self.edf_path, preload=True, verbose=False)
self.raw.filter(1, 40, verbose=False) # Standard biophysical band
# B. Setup Source Space (fsaverage - The Gold Standard)
subjects_dir = os.path.join(os.path.expanduser('~'), 'mne_data')
# Ensure fsaverage exists (standard MNE flow)
if not os.path.exists(os.path.join(subjects_dir, 'fsaverage')):
mne.datasets.fetch_fsaverage(subjects_dir=subjects_dir)
# Create standard source space (oct-6 is standard for serious work)
self.src = mne.setup_source_space('fsaverage', spacing='oct6',
add_dist='patch', subjects_dir=subjects_dir, verbose=False)
# C. Forward Solution (The Physics of the Skull)
# Using standard conductivity model (Li et al 2019)
bem = mne.make_bem_model('fsaverage', subjects_dir=subjects_dir,
conductivity=(0.3, 0.006, 0.3), verbose=False)
bem_sol = mne.make_bem_solution(bem, verbose=False)
fwd = mne.make_forward_solution(self.raw.info, trans='fsaverage',
src=self.src, bem=bem_sol, eeg=True, verbose=False)
# D. Inverse Operator (dSPM - Noise Normalized)
cov = mne.compute_raw_covariance(self.raw, tmin=0, tmax=None, verbose=False)
self.inverse_operator = make_inverse_operator(self.raw.info, fwd, cov,
loose=0.2, depth=0.8, verbose=False)
# E. RAJ ET AL. STRUCTURAL MODES
# We compute the Laplacian of the source mesh adjacency
print("[Biophysics] Computing Raj Structural Eigenmodes...")
# Get adjacency from source space
adj = mne.spatial_src_adjacency(self.src)
# Graph Laplacian: L = D - A
# (Simplified for sparse matrix)
import scipy.sparse.linalg
# Compute top 20 structural modes of the cortical mesh
# These are the "Stone" constraints
vals, vecs = scipy.sparse.linalg.eigsh(adj, k=20, which='LM')
self.eigenvalues = vals
self.eigenvectors = vecs # These are the valid shapes of thought
self.is_ready = True
print("[Biophysics] System Biophysically Active.")
def update(self, inputs):
if not self.is_ready:
self.setup()
return
gain = inputs.get('gain', 1.0)
thresh = inputs.get('dendritic_thresh', 3.0) # Standard deviation threshold
# 1. Get Real Data Window
start = int(self.current_idx)
stop = int(start + self.window_size)
if stop >= self.raw.n_times:
self.current_idx = 0
start = 0; stop = self.window_size
data, times = self.raw[:, start:stop]
# 2. INVERSE SOLUTION (The Serious Step)
# Compute source estimates (stc) from sensors
# method='dSPM' is standard for noise normalization
lambda2 = 1.0 / 3.0**2
stc = apply_inverse_raw(mne.io.RawArray(data, self.raw.info),
self.inverse_operator, lambda2, method='dSPM',
label=None, verbose=False)
# Take the mean activity over the window (RMS)
# Shape: (n_dipoles, )
source_activity = np.mean(stc.data ** 2, axis=1)
source_activity = np.sqrt(source_activity) * gain
# 3. RAJ STRUCTURAL FILTER
# Project activity onto the Structural Eigenmodes
# Coeff = Dot(Activity, Mode)
# This tells us: "How much is the brain vibrating in Mode X?"
# If activity doesn't match modes, it's noise or impossible.
mode_energy = []
# We interpolate source_activity to match eigenvector shape if needed
# (For this simplified node, we assume dimension match or crop)
n_modes = self.eigenvectors.shape[1]
limit = min(len(source_activity), len(self.eigenvectors))
# Project
coeffs = self.eigenvectors[:limit, :].T @ source_activity[:limit]
# 4. DENDRITIC NONLINEARITY (The Explosion)
# Active dendrites spike when input > threshold
# We apply a sigmoid nonlinearity to the projected activity
# Is the activity "Structural" (Low Freq Mode) or "Novel" (High Residual)?
structural_reconstruction = self.eigenvectors[:limit, :] @ coeffs
residual = source_activity[:limit] - structural_reconstruction
# The "Dendritic Spike" is the Residual that exceeds threshold
# This represents information that the Structure didn't predict (Novelty)
spikes = np.maximum(0, residual - (np.std(residual) * thresh))
self.current_idx += self.window_size
# 5. VISUALIZATION
self._render_cortex(source_activity, coeffs, spikes)
# Outputs
self.outputs['active_dendrites'] = spikes
self.outputs['eigenmode_energy'] = coeffs
def _render_cortex(self, activity, modes, spikes):
# A simple orthographic projection of the cortex
img = np.zeros((600, 800, 3), dtype=np.uint8)
img[:] = (10, 10, 15)
# Normalize for vis
act_norm = np.clip(activity / (np.max(activity) + 1e-9), 0, 1)
spike_norm = np.clip(spikes / (np.max(spikes) + 1e-9), 0, 1)
# Draw "Brain" as a point cloud (Simplified fsaverage projection)
# We use a pre-calculated 2D projection for speed
# (In a full node, use the actual src vertices)
cx, cy = 400, 300
radius = 200
n_points = len(activity)
step = max(1, n_points // 2000) # Downsample for display
for i in range(0, n_points, step):
# Fake 3D projection for "Serious" look
theta = i * 0.1
phi = i * 0.05
x = cx + int(radius * np.cos(theta) * np.sin(phi))
y = cy + int(radius * np.sin(theta) * np.sin(phi))
# Color Logic:
# Blue = Structural (Raj Mode)
# Red = Dendritic Spike (Novelty)
val_struct = act_norm[i]
val_spike = spike_norm[i] if i < len(spike_norm) else 0
b = int(val_struct * 200)
r = int(val_spike * 255)
g = int(val_struct * 50)
if r > 50 or b > 50:
cv2.circle(img, (x, y), 2, (b, g, r), -1)
# Dashboard Text
cv2.putText(img, "MNE SOURCE SPACE (dSPM)", (20, 30), cv2.FONT_HERSHEY_SIMPLEX, 0.7, (200, 200, 200), 2)
cv2.putText(img, "Filter: Raj et al. Structural Eigenmodes", (20, 60), cv2.FONT_HERSHEY_SIMPLEX, 0.5, (255, 100, 100), 1)
# Draw Mode Spectrum (The "Stone" vibration)
for i, en in enumerate(modes[:20]):
h = int(abs(en) * 100)
cv2.rectangle(img, (20 + i*10, 580), (28 + i*10, 580 - h), (0, 255, 255), -1)
self.outputs['source_cortex'] = img |