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Update data/rag/knowledge_base/Acinetobacter/baumannii.json
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{
"schema_version": "1.0",
"level": "species",
"genus": "Acinetobacter",
"species": "baumannii",
"overview": {
"short": "Acinetobacter baumannii is a Gram-negative, strictly aerobic, non-fermentative coccobacillus associated with severe healthcare-associated infections.",
"clinical_context": "A major cause of ventilator-associated pneumonia, bloodstream infections, wound infections, and outbreaks in intensive care units."
},
"expected_fields": {
"Gram Stain": "Negative",
"Shape": "Coccobacilli",
"Motility": "Negative",
"Capsule": "Variable",
"Spore Formation": "Negative",
"Haemolysis": "Negative",
"Haemolysis Type": "None",
"Media Grown On": [
"Blood Agar",
"MacConkey Agar"
],
"Colony Morphology": [
"Smooth",
"Opaque",
"Grey-White"
],
"Oxygen Requirement": "Aerobic",
"Growth Temperature": "20//44",
"Catalase": "Positive",
"Oxidase": "Negative",
"Indole": "Negative",
"Urease": "Variable",
"Citrate": "Variable",
"Methyl Red": "Negative",
"VP": "Negative",
"H2S": "Negative",
"DNase": "Variable",
"ONPG": "Negative",
"Coagulase": "Negative",
"Gelatin Hydrolysis": "Variable",
"Esculin Hydrolysis": "Negative",
"Nitrate Reduction": "Negative",
"NaCl Tolerant (>=6%)": "Positive",
"Lipase Test": "Variable",
"Lysine Decarboxylase": "Negative",
"Ornithine Decarboxylase": "Negative",
"Ornitihine Decarboxylase": "Negative",
"Arginine dihydrolase": "Negative",
"Glucose Fermentation": "Negative",
"Lactose Fermentation": "Negative",
"Sucrose Fermentation": "Negative",
"Maltose Fermentation": "Negative",
"Mannitol Fermentation": "Variable",
"Sorbitol Fermentation": "Negative",
"Xylose Fermentation": "Negative",
"Rhamnose Fermentation": "Negative",
"Arabinose Fermentation": "Negative",
"Raffinose Fermentation": "Negative",
"Trehalose Fermentation": "Negative",
"Inositol Fermentation": "Negative",
"Gas Production": "Negative",
"TSI Pattern": "K/K",
"Colony Pattern": "Unknown",
"Pigment": "None",
"Motility Type": "None"
},
"species_markers": [
{
"field": "NaCl Tolerant (>=6%)",
"value": "Positive",
"importance": "high",
"notes": "Salt tolerance supports A. baumannii over many other Acinetobacter species."
},
{
"field": "Growth Temperature",
"value": "44//44",
"importance": "high",
"notes": "Growth at elevated temperatures is characteristic of A. baumannii."
}
],
"common_confusions": [
{
"species": "Acinetobacter pittii",
"reason": "Part of the A. baumannii complex with overlapping biochemical profiles."
},
{
"species": "Acinetobacter calcoaceticus",
"reason": "Closely related environmental species within the complex."
}
],
"when_to_question_identification": [
"Failure to grow at elevated temperatures suggests a non-baumannii species.",
"Environmental isolation without clinical context may indicate another Acinetobacter species."
],
"recommended_next_tests": [
{
"test": "MALDI-TOF MS",
"reason": "Accurate differentiation within the Acinetobacter baumannii complex."
},
{
"test": "Antimicrobial susceptibility testing",
"reason": "Critical due to frequent multidrug resistance."
},
{
"test": "Molecular identification",
"reason": "Definitive species-level confirmation when clinically significant."
}
]
}