| { |
| "schema_version": "1.0", |
| "level": "species", |
| "genus": "Candida", |
| "species": "glabrata", |
|
|
| "overview": { |
| "short": "Candida glabrata is a small, non-dimorphic yeast with limited carbohydrate utilisation.", |
| "clinical_context": "An important cause of bloodstream and urinary tract infections, often associated with antifungal resistance." |
| }, |
|
|
| "expected_fields": { |
| "Gram Stain": "Positive", |
| "Shape": "Yeast", |
| "Motility": "Negative", |
| "Capsule": "Negative", |
| "Spore Formation": "Negative", |
| "Haemolysis": "Negative", |
| "Haemolysis Type": "None", |
| "Media Grown On": [ |
| "Sabouraud Dextrose Agar", |
| "Chromogenic Candida Agar" |
| ], |
| "Colony Morphology": [ |
| "Small", |
| "Cream", |
| "Smooth" |
| ], |
| "Oxygen Requirement": "Facultative Anaerobe", |
| "Growth Temperature": "25//40", |
| "Catalase": "Positive", |
| "Oxidase": "Negative", |
| "Indole": "Negative", |
| "Urease": "Negative", |
| "Citrate": "Negative", |
| "Methyl Red": "Negative", |
| "VP": "Negative", |
| "H2S": "Negative", |
| "DNase": "Negative", |
| "ONPG": "Negative", |
| "Coagulase": "Negative", |
| "Gelatin Hydrolysis": "Negative", |
| "Esculin Hydrolysis": "Negative", |
| "Nitrate Reduction": "Negative", |
| "NaCl Tolerant (>=6%)": "Variable", |
| "Lipase Test": "Negative", |
| "Lysine Decarboxylase": "Negative", |
| "Ornithine Decarboxylase": "Negative", |
| "Ornitihine Decarboxylase": "Negative", |
| "Arginine dihydrolase": "Negative", |
| "Glucose Fermentation": "Positive", |
| "Lactose Fermentation": "Negative", |
| "Sucrose Fermentation": "Negative", |
| "Maltose Fermentation": "Negative", |
| "Mannitol Fermentation": "Negative", |
| "Sorbitol Fermentation": "Negative", |
| "Xylose Fermentation": "Negative", |
| "Rhamnose Fermentation": "Negative", |
| "Arabinose Fermentation": "Negative", |
| "Raffinose Fermentation": "Negative", |
| "Trehalose Fermentation": "Positive", |
| "Inositol Fermentation": "Negative", |
| "Gas Production": "Negative", |
| "TSI Pattern": "Unknown", |
| "Colony Pattern": "Unknown", |
| "Pigment": "None", |
| "Motility Type": "None" |
| }, |
|
|
| "species_markers": [ |
| { |
| "field": "Germ Tube Test", |
| "value": "Negative", |
| "importance": "critical", |
| "notes": "Excludes Candida albicans." |
| }, |
| { |
| "field": "Trehalose Fermentation", |
| "value": "Positive", |
| "importance": "high", |
| "notes": "One of few sugars fermented by C. glabrata." |
| } |
| ], |
|
|
| "common_confusions": [ |
| { |
| "species": "Candida krusei", |
| "reason": "Both are germ-tube negative with limited fermentation profiles." |
| } |
| ], |
|
|
| "when_to_question_identification": [ |
| "Broad sugar fermentation profile argues against C. glabrata.", |
| "Hyphae or pseudohyphae formation suggests another Candida species." |
| ], |
|
|
| "recommended_next_tests": [ |
| { |
| "test": "Carbohydrate assimilation testing", |
| "reason": "Confirms restricted metabolic profile.", |
| "api_kit": "API Candida" |
| }, |
| { |
| "test": "Antifungal susceptibility testing", |
| "reason": "High likelihood of azole resistance." |
| } |
| ] |
| } |
