File size: 6,048 Bytes
c4f9a44
8a8c9e1
34a9c67
df3ee3f
c4f9a44
f20e1e0
c9e0e70
 
c4f9a44
 
c9e0e70
a1b81e3
 
23f6964
67db196
3be6d9b
a1b81e3
 
c4f9a44
 
a1b81e3
c4f9a44
a1b81e3
c9e0e70
c4f9a44
c9e0e70
c4f9a44
 
 
 
a1b81e3
c4f9a44
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
9197033
d30be54
c4f9a44
 
d30be54
c4f9a44
a1b81e3
34a9c67
 
 
7787ff3
 
 
 
 
9197033
a1b81e3
34a9c67
 
7787ff3
c4f9a44
 
f20e1e0
 
 
c4f9a44
f20e1e0
c4f9a44
 
 
 
 
 
 
 
 
3be6d9b
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
a1b81e3
df3ee3f
 
 
 
 
 
 
 
 
 
d97e3ee
 
df3ee3f
 
 
 
 
67db196
 
 
d97e3ee
67db196
 
 
 
d97e3ee
67db196
 
d97e3ee
 
5793a9c
 
67db196
d97e3ee
 
 
 
 
c4f9a44
 
 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
import os
import sys
import gc
import base64
import tempfile
import traceback
import io
from flask import Flask, request, jsonify, send_file
from flask_cors import CORS

# Import the logic from the backend modules
from centerline_extraction import compute_centerlines_network, load_nrrd_as_vtk_image
from ostium_detection import extract_centerline_data
from endograft_generation import build_endograft_stl_payload
from maquette_generation import generate_fenestrated_maquette
from endograft_selection import start_endograft_pipeline

# Flask API server that wraps the VMTK centerline extraction, ostium detection, and endograft generation pipelines
app = Flask(__name__)
CORS(app)  # Allow cross-origin requests from the Next.js frontend
app.config["MAX_CONTENT_LENGTH"] = 200 * 1024 * 1024 # Maximum file upload size (200 MB)

# Simple health check so the deployment platform knows the server is running
@app.route("/health", methods=["GET"])
def health():
  return jsonify({"status": "ok"})

# Runs the full VMTK centerline extraction pipeline on NRRD segmentation and returns the result as JSON
@app.route("/extract", methods=["POST"])
def extract():
  # Check that the segmentation file sent to the centerline extraction endpoint exists and is an NRRD file
  if "file" not in request.files:
    return jsonify({"status": "error", "error": "No file provided"}), 400

  uploaded = request.files["file"]
  file_name = uploaded.filename.lower()
  if not file_name.endswith(".nrrd"):
    return jsonify({"status": "error", "error": "Invalid File Type. Allowed: .nrrd"}), 400

  # Save to a temp file so VMTK can read it from disk
  tmp = tempfile.NamedTemporaryFile(suffix=".nrrd", delete=False)
  try:
    uploaded.save(tmp.name)
    tmp.close()

    # Read the NRRD segmentation via SimpleITK (preserves full direction matrix)
    image, origin, direction = load_nrrd_as_vtk_image(tmp.name)

    # Voronoi centerline extraction
    centerlines, branch_junctions = compute_centerlines_network(image, origin, direction)

    # Extract labelled segments and artery bifurcation data
    data = extract_centerline_data(centerlines, branch_junctions=branch_junctions)

    # Free the large VTK pipeline objects immediately
    del centerlines, branch_junctions
    gc.collect()

    # Include the NRRD image's physical extent so the frontend can normalize the centerline
    dims = image.GetDimensions()
    spacing = image.GetSpacing()
    phys_size = [dims[i] * spacing[i] for i in range(3)]
    phys_center = [origin[i] + phys_size[i] / 2.0 for i in range(3)]
    data['volume_info'] = {'center': {'x': phys_center[0], 'y': phys_center[1], 'z': phys_center[2]}, 'size': {'x': phys_size[0], 'y': phys_size[1], 'z': phys_size[2]}}

    del image
    gc.collect()

    return jsonify({"status": "success", "data": data})

  except TimeoutError as e:
    return jsonify({"status": "error", "error": str(e)}), 504

  except Exception as e:
    traceback.print_exc()
    return jsonify({"status": "error", "error": str(e)}), 500

  finally:
    # Always clean up the temp file
    try:
      os.unlink(tmp.name)
    except OSError:
      pass

# Runs the endograft selection pipeline on computed bounds of aneurysm
@app.route("/select_graft", methods=["POST"])
def select_graft():
  body = request.get_json(silent=True) or {}
  proximal_diameter = body.get("proximal_diameter", 0)
  distal_diameter = body.get("distal_diameter", 0)
  proximal_start_point = body.get("proximal_start_point")
  distal_end_point = body.get("distal_end_point")
  length = body.get("length", 0)
  fenestrations_exist = body.get("fenestrations_exist", False)
  distance_to_last_fenestration = body.get("distance_to_last_fenestration", 0)

  try:
    selected_graft = start_endograft_pipeline(
      proximal_diameter, distal_diameter, proximal_start_point, distal_end_point, length, fenestrations_exist, distance_to_last_fenestration
    )
    return jsonify({"status": "success", "data": selected_graft})
  except Exception as e:
    traceback.print_exc()
    return jsonify({"status": "error", "error": str(e)}), 500

# Runs the endograft generation pipeline on VMTK centerline and returns the result as JSON
@app.route("/endograft", methods=["POST"])
def endograft():
  body = request.get_json(silent=True) or {}
  centerline = body.get("centerline")
  params = body.get("params") or {}

  if not isinstance(centerline, list) or len(centerline) < 2:
    return jsonify({"status": "error", "error": "centerline must be a list of at least 2 points"}), 400

  try:
    payload = build_endograft_stl_payload(centerline, include_combined=False, **params)
    result = {"endograft_stl_b64": base64.b64encode(payload["endograft"]).decode("utf-8"), "struts_stl_b64": base64.b64encode(payload["struts"]).decode("utf-8")}
    return jsonify({"status": "success", "data": result})
  except Exception as e:
    traceback.print_exc()
    return jsonify({"status": "error", "error": str(e)}), 500

# Generates endograft STL maquette
@app.route("/maquette", methods=["POST"])
def maquette():
  body = request.get_json(silent=True) or {}
  centerline = body.get("centerline")
  params = body.get("params") or {}
  fenestrations = body.get("fenestrations") or []
  include_struts = body.get("include_struts", True)

  if not isinstance(centerline, list) or len(centerline) < 2:
    return jsonify({"status": "error", "error": "centerline must be a list of at least 2 points"}), 400

  try:
    stl_bytes = generate_fenestrated_maquette(centerline, params, fenestrations, include_struts)
    result = {"maquette_stl_b64": base64.b64encode(stl_bytes).decode("utf-8")}
    return jsonify({"status": "success", "data": result})
  except Exception as e:
    traceback.print_exc()
    return jsonify({"status": "error", "error": str(e)}), 500


if __name__ == "__main__":
  port = int(os.environ.get("PORT", 5050))
  app.run(host="0.0.0.0", port=port)