leadboard / data /bace1_card.json
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boards: add proteases, nuclear receptors, epigenetics (8 boards)
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{
"board": "BACE1",
"target": "CHEMBL4822",
"type": "IC50",
"cut": 2022,
"threshold": 7.0,
"n_train": 7993,
"n_test": 278,
"positive_rate": 0.39928057553956836,
"noise_floor": {
"pairs": 3170,
"compounds": 1689,
"median": 0.0,
"mean": 0.23903933312249104,
"p75": 0.19010562085580318,
"p90": 0.7051303130408373,
"sd_single": 0.2119143024135559
},
"baselines": {
"์ƒ์ˆ˜ ์˜ˆ์ธก": {
"auroc": 0.5,
"prauc": 0.39928057553956836,
"mae": 1.369326880055476
},
"์ตœ๊ทผ์ ‘ ์ด์›ƒ": {
"auroc": 0.7420834007660355,
"prauc": 0.5956653942265453,
"mae": 1.0779046140060264
},
"Morgan+LightGBM": {
"auroc": 0.9232885580190969,
"prauc": 0.8798898313498296,
"mae": 0.9674177988332499
}
},
"near_threshold": 15,
"split_grade": "T",
"split_grade_note": "์ตœ์ดˆ ๋ณด๊ณ  ์—ฐ๋„ ๊ธฐ์ค€ ์‹œ๊ฐ„ ๋ถ„ํ• ",
"answer_grade": "P1",
"answer_grade_note": "์ •๋‹ต์ด ChEMBL ์— ๊ณต๊ฐœ๋˜์–ด ์žˆ๋‹ค. ์กฐํšŒ ๋ฐฉ์–ด๋Š” 8์กฐ๊ฐ€ ๋งก๋Š”๋‹ค",
"source": "ChEMBL_37",
"built": "2026-08-23"
}