leadboard / data /herg_card.json
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{
"board": "hERG",
"target": "CHEMBL240",
"type": "IC50",
"cut": 2022,
"threshold": 5.0,
"n_train": 8450,
"n_test": 1338,
"positive_rate": 0.585949177877429,
"noise_floor": {
"pairs": 5185,
"compounds": 857,
"median": 0.14793898523038607,
"mean": 0.47494876125752883,
"p75": 0.6690067809585756,
"p90": 1.3377444185444354,
"sd_single": 0.4210538663630575
},
"baselines": {
"์ƒ์ˆ˜ ์˜ˆ์ธก": {
"auroc": 0.5,
"prauc": 0.585949177877429,
"mae": 0.5887837936811489
},
"์ตœ๊ทผ์ ‘ ์ด์›ƒ": {
"auroc": 0.56607327046342,
"prauc": 0.6209289133630831,
"mae": 0.7761432713342975
},
"Morgan+LightGBM": {
"auroc": 0.6063324246666175,
"prauc": 0.703536813371362,
"mae": 0.5986207163323017
}
},
"near_threshold": 696,
"split_grade": "T",
"split_grade_note": "์ตœ์ดˆ ๋ณด๊ณ  ์—ฐ๋„ ๊ธฐ์ค€ ์‹œ๊ฐ„ ๋ถ„ํ• ",
"answer_grade": "P1",
"answer_grade_note": "์ •๋‹ต์ด ChEMBL ์— ๊ณต๊ฐœ๋˜์–ด ์žˆ๋‹ค. ์กฐํšŒ ๋ฐฉ์–ด๋Š” 8์กฐ๊ฐ€ ๋งก๋Š”๋‹ค",
"source": "ChEMBL_37",
"built": "2026-08-22"
}