SeaWolf-AI commited on
Commit
9995f5e
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verified ยท
1 Parent(s): 2b82572

boards: correct organism labels; add H37Rv-only TB board

Browse files
board_meta.json CHANGED
@@ -133,10 +133,6 @@
133
  "ko": "๋ง๋ผ๋ฆฌ์•„ ์›์ถฉ ์‚ฌ๋ฉธ โ€” ์ ํ˜ˆ๊ตฌ๋‚ด ๋‹จ๊ณ„",
134
  "en": "Malaria parasite kill โ€” blood stage"
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  },
136
- "BSubtilis": {
137
- "ko": "๊ทธ๋žŒ์–‘์„ฑ๊ท  ์‚ฌ๋ฉธ โ€” ์ „์„ธํฌ ํŒ์ •",
138
- "en": "Gram-positive kill โ€” whole-cell readout"
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- },
140
  "LD50": {
141
  "ko": "๊ธ‰์„ฑ๋…์„ฑ โ€” ์น˜์‚ฌ๋Ÿ‰",
142
  "en": "Acute toxicity โ€” lethal dose"
@@ -144,6 +140,54 @@
144
  "Selectivity": {
145
  "ko": "์‹ฌ์žฅ ์•ˆ์ „์—ญ โ€” ํ‘œ์  ์„ธ๊ธฐ์™€ hERG ์„ธ๊ธฐ์˜ ์ฐจ์ด",
146
  "en": "Cardiac safety margin โ€” target potency minus hERG"
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
147
  }
148
  }
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  }
 
133
  "ko": "๋ง๋ผ๋ฆฌ์•„ ์›์ถฉ ์‚ฌ๋ฉธ โ€” ์ ํ˜ˆ๊ตฌ๋‚ด ๋‹จ๊ณ„",
134
  "en": "Malaria parasite kill โ€” blood stage"
135
  },
 
 
 
 
136
  "LD50": {
137
  "ko": "๊ธ‰์„ฑ๋…์„ฑ โ€” ์น˜์‚ฌ๋Ÿ‰",
138
  "en": "Acute toxicity โ€” lethal dose"
 
140
  "Selectivity": {
141
  "ko": "์‹ฌ์žฅ ์•ˆ์ „์—ญ โ€” ํ‘œ์  ์„ธ๊ธฐ์™€ hERG ์„ธ๊ธฐ์˜ ์ฐจ์ด",
142
  "en": "Cardiac safety margin โ€” target potency minus hERG"
143
+ },
144
+ "BACE1": {
145
+ "ko": "์•Œ์ธ ํ•˜์ด๋จธ ํ‘œ์  โ€” ์•„๋ฐ€๋กœ์ด๋“œ ์ƒ์„ฑ ํšจ์†Œ",
146
+ "en": "Alzheimer target โ€” amyloid-producing protease"
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+ },
148
+ "BRD4": {
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+ "ko": "์—ํ”ผ์ œ๋„คํ‹ฑ ํ‘œ์  โ€” ์œ ์ „์ž ์ฝ๊ธฐ ์ฐจ๋‹จ",
150
+ "en": "Epigenetic target โ€” BET bromodomain"
151
+ },
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+ "HDAC1": {
153
+ "ko": "์—ํ”ผ์ œ๋„คํ‹ฑ ํ‘œ์  โ€” ํžˆ์Šคํ†ค ํƒˆ์•„์„ธํ‹ธํ™”",
154
+ "en": "Epigenetic target โ€” histone deacetylase"
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+ },
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+ "HIVRT": {
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+ "ko": "HIV ์—ญ์ „์‚ฌํšจ์†Œ โ€” ํ•ญ๋ฐ”์ด๋Ÿฌ์Šค",
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+ "en": "HIV reverse transcriptase โ€” antiviral"
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+ },
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+ "Nav17": {
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+ "ko": "๋งŒ์„ฑ ํ†ต์ฆ ํ‘œ์  โ€” ๋น„๋งˆ์•ฝ์„ฑ ์ง„ํ†ต ํ›„๋ณด",
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+ "en": "Chronic pain target โ€” non-opioid analgesia"
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+ },
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+ "ERalpha": {
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+ "ko": "์œ ๋ฐฉ์•” ํ‘œ์  โ€” ์—์ŠคํŠธ๋กœ๊ฒ ์ˆ˜์šฉ์ฒด",
166
+ "en": "Breast cancer target โ€” estrogen receptor alpha"
167
+ },
168
+ "Thrombin": {
169
+ "ko": "ํ•ญ์‘๊ณ  ํ‘œ์  โ€” ํ˜ˆ์ „ ํ˜•์„ฑ ํšจ์†Œ",
170
+ "en": "Anticoagulant target โ€” thrombin"
171
+ },
172
+ "FactorXa": {
173
+ "ko": "ํ•ญ์‘๊ณ  ํ‘œ์  โ€” ์ œ10์ธ์ž Xa",
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+ "en": "Anticoagulant target โ€” factor Xa"
175
+ },
176
+ "AR": {
177
+ "ko": "์ „๋ฆฝ์„ ์•” ํ‘œ์  โ€” ์•ˆ๋“œ๋กœ๊ฒ ์ˆ˜์šฉ์ฒด",
178
+ "en": "Prostate cancer target โ€” androgen receptor"
179
+ },
180
+ "HIVPR": {
181
+ "ko": "HIV ํ”„๋กœํ…Œ์•„์ œ โ€” ํ•ญ๋ฐ”์ด๋Ÿฌ์Šค",
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+ "en": "HIV protease โ€” antiviral"
183
+ },
184
+ "SEpidermidis": {
185
+ "ko": "ํ‘œํ”ผํฌ๋„์ƒ๊ตฌ๊ท  โ€” ์ „์„ธํฌ ํŒ์ •",
186
+ "en": "S. epidermidis โ€” whole-cell readout"
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+ },
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+ "MTB": {
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+ "ko": "๊ฒฐํ•ต๊ท  โ€” ํ‘œ์ค€๊ท ์ฃผ H37Rv ์ „์„ธํฌ ํŒ์ •",
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+ "en": "M. tuberculosis H37Rv โ€” whole-cell readout"
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  }
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  }
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  }
categories.json CHANGED
@@ -194,7 +194,8 @@
194
  "planned": 6,
195
  "boards": [
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  "Malaria",
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- "BSubtilis"
 
198
  ]
199
  },
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  {
 
194
  "planned": 6,
195
  "boards": [
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  "Malaria",
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+ "SEpidermidis",
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+ "MTB"
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  ]
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  },
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  {
data/bsubtilis_test.json DELETED
The diff for this file is too large to render. See raw diff
 
data/mtb_card.json ADDED
@@ -0,0 +1,48 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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+ {
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+ "board": "MTB",
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+ "target": "โ€”",
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+ "type": "pMIC (์ „์„ธํฌ ์ตœ์†Œ์–ต์ œ๋†๋„)",
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+ "cut": 2020,
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+ "threshold": 4.5,
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+ "n_train": 12588,
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+ "n_test": 2931,
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+ "positive_rate": 0.7359263050153532,
10
+ "noise_floor": {
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+ "pairs": 235128,
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+ "compounds": 504,
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+ "median": 0.5016894462103991,
14
+ "mean": 0.6808064487933246,
15
+ "p75": 0.9208187539523749,
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+ "p90": 1.5105215264340135,
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+ "sd_single": 0.603551816306139
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+ },
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+ "baselines": {
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+ "์ƒ์ˆ˜ ์˜ˆ์ธก": {
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+ "auroc": 0.5,
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+ "prauc": 0.7359263050153532,
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+ "mae": 0.9169051070518842
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+ },
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+ "์ตœ๊ทผ์ ‘ ์ด์›ƒ": {
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+ "auroc": 0.5983745009038537,
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+ "prauc": 0.7770305980411635,
28
+ "mae": 0.9757214652005455
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+ },
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+ "Morgan+LightGBM": {
31
+ "auroc": 0.6697259328740391,
32
+ "prauc": 0.8538416770414989,
33
+ "mae": 0.8062822382727481
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+ }
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+ },
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+ "near_threshold": 1193,
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+ "split_grade": "T",
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+ "split_grade_note": "์ตœ์ดˆ ๋ณด๊ณ  ์—ฐ๋„ ๊ธฐ์ค€ ์‹œ๊ฐ„ ๋ถ„ํ• ",
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+ "answer_grade": "P2",
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+ "answer_grade_note": "์›์ž๋ฃŒ๋Š” ๊ณต๊ฐœ์ง€๋งŒ ๋‹จ์œ„ ํ™˜์‚ฐ๊ณผ ์„ ๋ณ„์ด ๋ณธ ํŒ๋ณธ์„ ๋งŒ๋“ ๋‹ค",
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+ "assay_keep": "H37Rv",
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+ "assay_drop": "resistant|MDR|XDR|CNCTC|clinical isolate|Erdman|Beijing|CDC1551|H37Ra",
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+ "source": "ChEMBL_37 ์žฌํ๋ ˆ์ด์…˜",
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+ "axis": "X",
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+ "desc_ko": "๊ฒฐํ•ต๊ท  - ํ‘œ์ค€๊ท ์ฃผ H37Rv ์ „์„ธํฌ ์‚ฌ๋ฉธ",
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+ "desc_en": "M. tuberculosis H37Rv whole-cell kill",
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+ "built": "2026-08-24"
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+ }
data/mtb_test.json ADDED
The diff for this file is too large to render. See raw diff
 
data/{bsubtilis_card.json โ†’ sepidermidis_card.json} RENAMED
@@ -1,5 +1,5 @@
1
  {
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- "board": "BSubtilis",
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  "target": "โ€”",
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  "type": "pMIC (์ „์„ธํฌ ์ตœ์†Œ์–ต์ œ๋†๋„)",
5
  "cut": 2018,
@@ -38,9 +38,11 @@
38
  "split_grade_note": "์ตœ์ดˆ ๋ณด๊ณ  ์—ฐ๋„ ๊ธฐ์ค€ ์‹œ๊ฐ„ ๋ถ„ํ• ",
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  "answer_grade": "P2",
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  "answer_grade_note": "์›์ž๋ฃŒ๋Š” ๊ณต๊ฐœ์ง€๋งŒ ๋‹จ์œ„ ํ™˜์‚ฐ๊ณผ ์„ ๋ณ„์ด ๋ณธ ํŒ๋ณธ์„ ๋งŒ๋“ ๋‹ค",
 
 
41
  "source": "ChEMBL_37 ์žฌํ๋ ˆ์ด์…˜",
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  "axis": "X",
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- "desc_ko": "๊ณ ์ดˆ๊ท  - ์ „์„ธํฌ ์‚ฌ๋ฉธ",
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- "desc_en": "B. subtilis whole-cell kill",
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- "built": "2026-08-22"
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  }
 
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  {
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+ "board": "SEpidermidis",
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  "target": "โ€”",
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  "type": "pMIC (์ „์„ธํฌ ์ตœ์†Œ์–ต์ œ๋†๋„)",
5
  "cut": 2018,
 
38
  "split_grade_note": "์ตœ์ดˆ ๋ณด๊ณ  ์—ฐ๋„ ๊ธฐ์ค€ ์‹œ๊ฐ„ ๋ถ„ํ• ",
39
  "answer_grade": "P2",
40
  "answer_grade_note": "์›์ž๋ฃŒ๋Š” ๊ณต๊ฐœ์ง€๋งŒ ๋‹จ์œ„ ํ™˜์‚ฐ๊ณผ ์„ ๋ณ„์ด ๋ณธ ํŒ๋ณธ์„ ๋งŒ๋“ ๋‹ค",
41
+ "assay_keep": null,
42
+ "assay_drop": null,
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  "source": "ChEMBL_37 ์žฌํ๋ ˆ์ด์…˜",
44
  "axis": "X",
45
+ "desc_ko": "ํ‘œํ”ผํฌ๋„์ƒ๊ตฌ๊ท  - ์ „์„ธํฌ ์‚ฌ๋ฉธ",
46
+ "desc_en": "S. epidermidis whole-cell kill",
47
+ "built": "2026-08-24"
48
  }
data/sepidermidis_test.json ADDED
The diff for this file is too large to render. See raw diff