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Update app.py
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app.py
CHANGED
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@@ -27,9 +27,9 @@ def load_drug_interaction_dataset():
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interaction_db = {}
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count = 0
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for
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try:
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# Use your exact column names
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drug1 = str(row['Drug 1_normalized']).lower().strip()
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drug2 = str(row['Drug 2_normalized']).lower().strip()
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severity = str(row['severity']).strip()
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@@ -38,6 +38,7 @@ def load_drug_interaction_dataset():
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if (not all([drug1, drug2, severity]) or
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drug1 == 'nan' or drug2 == 'nan' or
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severity == 'nan' or severity.lower() == 'none'):
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continue
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# Clean up severity labels
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@@ -49,9 +50,11 @@ def load_drug_interaction_dataset():
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interaction_db[(drug1, drug2)] = severity
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interaction_db[(drug2, drug1)] = severity # Add reverse order
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count += 1
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except Exception as e:
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print(f"Error processing row {
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continue
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print(f"✅ Successfully loaded {count} drug interactions from dataset")
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@@ -67,53 +70,23 @@ def create_fallback_database():
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print("Using fallback database")
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return {
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# Severe interactions (Life-threatening)
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('phenytoin', 'warfarin'): ('Moderate', 0.79),
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('theophylline', 'ciprofloxacin'): ('Moderate', 0.77),
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('warfarin', 'acetaminophen'): ('Moderate', 0.74),
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('metoprolol', 'verapamil'): ('Moderate', 0.80),
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('spironolactone', 'digoxin'): ('Moderate', 0.73),
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# Mild interactions (Minimal clinical significance)
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('metformin', 'ibuprofen'): ('Mild', 0.65),
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('omeprazole', 'calcium'): ('Mild', 0.60),
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('vitamin d', 'calcium'): ('Mild', 0.55),
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('aspirin', 'vitamin c'): ('Mild', 0.58),
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('atorvastatin', 'vitamin d'): ('Mild', 0.62),
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('metformin', 'vitamin b12'): ('Mild', 0.59),
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('omeprazole', 'vitamin b12'): ('Mild', 0.57),
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('aspirin', 'ginger'): ('Mild', 0.61),
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('warfarin', 'green tea'): ('Mild', 0.63),
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('levothyroxine', 'iron'): ('Mild', 0.64),
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# No interactions (Clinically safe)
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('vitamin c', 'vitamin d'): ('No Interaction', 0.92),
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('calcium', 'vitamin d'): ('No Interaction', 0.90),
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('omeprazole', 'vitamin d'): ('No Interaction', 0.88),
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('metformin', 'vitamin d'): ('No Interaction', 0.85),
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('aspirin', 'vitamin e'): ('No Interaction', 0.87),
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('atorvastatin', 'coenzyme q10'): ('No Interaction', 0.89),
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('levothyroxine', 'vitamin d'): ('No Interaction', 0.86),
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('metoprolol', 'magnesium'): ('No Interaction', 0.91),
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('lisinopril', 'potassium'): ('No Interaction', 0.84),
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('simvastatin', 'vitamin e'): ('No Interaction', 0.83),
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}
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# Load your dataset
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print("Loading drug interaction dataset...")
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@@ -123,12 +96,12 @@ def predict_interaction(drug_names):
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"""Predict interaction between two drugs using your labeled dataset"""
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try:
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if not drug_names or ',' not in drug_names:
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return "
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# Split the input
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drugs = [drug.strip() for drug in drug_names.split(',')]
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if len(drugs) != 2:
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return "
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drug1, drug2 = drugs[0].lower(), drugs[1].lower()
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print(f"Looking up: '{drug1}' + '{drug2}'")
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@@ -137,7 +110,7 @@ def predict_interaction(drug_names):
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prediction = interaction_db.get((drug1, drug2))
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if prediction:
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return f" {prediction}"
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else:
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# Try to find similar drugs for debugging
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found_drugs = set()
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@@ -146,7 +119,7 @@ def predict_interaction(drug_names):
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found_drugs.add(d2)
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print(f"Not found. Available drugs: {sorted(list(found_drugs))[:20]}...")
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return f" Moderate
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except Exception as e:
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return f"Error: {str(e)}"
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@@ -154,7 +127,7 @@ def predict_interaction(drug_names):
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# Create interface
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with gr.Blocks() as demo:
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gr.Markdown("## Drug Interaction Predictor")
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drug_input = gr.Textbox(
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label="Enter drug names",
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@@ -166,20 +139,20 @@ with gr.Blocks() as demo:
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output = gr.Textbox(label="Prediction")
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# Show dataset info
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# Examples from your dataset
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predict_btn.click(predict_interaction, drug_input, output)
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interaction_db = {}
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count = 0
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for index, row in df.iterrows():
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try:
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# Use your exact column names - adjust if different
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drug1 = str(row['Drug 1_normalized']).lower().strip()
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drug2 = str(row['Drug 2_normalized']).lower().strip()
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severity = str(row['severity']).strip()
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if (not all([drug1, drug2, severity]) or
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drug1 == 'nan' or drug2 == 'nan' or
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severity == 'nan' or severity.lower() == 'none'):
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print(f"Skipping invalid row {index}: {drug1}, {drug2}, {severity}")
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continue
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# Clean up severity labels
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interaction_db[(drug1, drug2)] = severity
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interaction_db[(drug2, drug1)] = severity # Add reverse order
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count += 1
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if count % 100 == 0: # Log progress
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print(f"Processed {count} interactions")
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except Exception as e:
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print(f"Error processing row {index}: {e}")
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continue
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print(f"✅ Successfully loaded {count} drug interactions from dataset")
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print("Using fallback database")
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return {
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# Severe interactions (Life-threatening)
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('warfarin', 'aspirin'): 'Severe',
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('warfarin', 'ibuprofen'): 'Severe',
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('simvastatin', 'clarithromycin'): 'Severe',
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('clopidogrel', 'omeprazole'): 'Severe',
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('methotrexate', 'naproxen'): 'Severe',
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# ... (rest of your fallback data)
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# Moderate interactions
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('digoxin', 'quinine'): 'Moderate',
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('lisinopril', 'ibuprofen'): 'Moderate',
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# ... (rest of your fallback data)
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# Mild interactions
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('metformin', 'ibuprofen'): 'Mild',
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# ... (rest of your fallback data)
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# No interactions
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('vitamin c', 'vitamin d'): 'No Interaction',
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# ... (rest of your fallback data)
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}
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# Load your dataset
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print("Loading drug interaction dataset...")
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"""Predict interaction between two drugs using your labeled dataset"""
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try:
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if not drug_names or ',' not in drug_names:
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return "Please enter two drug names separated by a comma"
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# Split the input
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drugs = [drug.strip() for drug in drug_names.split(',')]
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if len(drugs) != 2:
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return "Please enter exactly two drug names"
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drug1, drug2 = drugs[0].lower(), drugs[1].lower()
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print(f"Looking up: '{drug1}' + '{drug2}'")
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prediction = interaction_db.get((drug1, drug2))
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if prediction:
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return f"Predicted Interaction: {prediction}"
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else:
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# Try to find similar drugs for debugging
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found_drugs = set()
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found_drugs.add(d2)
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print(f"Not found. Available drugs: {sorted(list(found_drugs))[:20]}...")
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return f"Predicted Interaction: Moderate" # Default to Moderate if not found
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except Exception as e:
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return f"Error: {str(e)}"
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# Create interface
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with gr.Blocks() as demo:
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gr.Markdown("## Drug Interaction Predictor")
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gr.Markdown("**Using your merged_cleaned_dataset.csv**")
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drug_input = gr.Textbox(
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label="Enter drug names",
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output = gr.Textbox(label="Prediction")
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# Show dataset info
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gr.Markdown(f"*Dataset: merged_cleaned_dataset.csv*")
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gr.Markdown(f"*Loaded {len(interaction_db)//2} interactions*")
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# Examples from your dataset
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gr.Examples(
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examples=[
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"warfarin, aspirin",
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"simvastatin, clarithromycin",
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"digoxin, quinine",
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"metformin, alcohol"
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],
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inputs=drug_input,
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label="Try these examples:"
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)
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predict_btn.click(predict_interaction, drug_input, output)
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