Fredaaaaaa commited on
Commit
28b4311
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1 Parent(s): 3de2931

Update app.py

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Files changed (1) hide show
  1. app.py +40 -67
app.py CHANGED
@@ -27,9 +27,9 @@ def load_drug_interaction_dataset():
27
  interaction_db = {}
28
  count = 0
29
 
30
- for _, row in df.iterrows():
31
  try:
32
- # Use your exact column names
33
  drug1 = str(row['Drug 1_normalized']).lower().strip()
34
  drug2 = str(row['Drug 2_normalized']).lower().strip()
35
  severity = str(row['severity']).strip()
@@ -38,6 +38,7 @@ def load_drug_interaction_dataset():
38
  if (not all([drug1, drug2, severity]) or
39
  drug1 == 'nan' or drug2 == 'nan' or
40
  severity == 'nan' or severity.lower() == 'none'):
 
41
  continue
42
 
43
  # Clean up severity labels
@@ -49,9 +50,11 @@ def load_drug_interaction_dataset():
49
  interaction_db[(drug1, drug2)] = severity
50
  interaction_db[(drug2, drug1)] = severity # Add reverse order
51
  count += 1
 
 
52
 
53
  except Exception as e:
54
- print(f"Error processing row {_}: {e}")
55
  continue
56
 
57
  print(f"✅ Successfully loaded {count} drug interactions from dataset")
@@ -67,53 +70,23 @@ def create_fallback_database():
67
  print("Using fallback database")
68
  return {
69
  # Severe interactions (Life-threatening)
70
- ('warfarin', 'aspirin'): ('Severe', 0.96),
71
- ('warfarin', 'ibuprofen'): ('Severe', 0.94),
72
- ('simvastatin', 'clarithromycin'): ('Severe', 0.95),
73
- ('clopidogrel', 'omeprazole'): ('Severe', 0.88),
74
- ('methotrexate', 'naproxen'): ('Severe', 0.92),
75
- ('lithium', 'ibuprofen'): ('Severe', 0.89),
76
- ('ssri', 'maoi'): ('Severe', 0.97),
77
- ('simvastatin', 'verapamil'): ('Severe', 0.93),
78
- ('warfarin', 'fluconazole'): ('Severe', 0.91),
79
- ('digoxin', 'verapamil'): ('Severe', 0.90),
80
-
81
- # Moderate interactions (Requires monitoring)
82
- ('digoxin', 'quinine'): ('Moderate', 0.82),
83
- ('lisinopril', 'ibuprofen'): ('Moderate', 0.78),
84
- ('metformin', 'alcohol'): ('Moderate', 0.76),
85
- ('levothyroxine', 'calcium'): ('Moderate', 0.81),
86
- ('atorvastatin', 'orange juice'): ('Moderate', 0.75),
87
- ('phenytoin', 'warfarin'): ('Moderate', 0.79),
88
- ('theophylline', 'ciprofloxacin'): ('Moderate', 0.77),
89
- ('warfarin', 'acetaminophen'): ('Moderate', 0.74),
90
- ('metoprolol', 'verapamil'): ('Moderate', 0.80),
91
- ('spironolactone', 'digoxin'): ('Moderate', 0.73),
92
-
93
- # Mild interactions (Minimal clinical significance)
94
- ('metformin', 'ibuprofen'): ('Mild', 0.65),
95
- ('omeprazole', 'calcium'): ('Mild', 0.60),
96
- ('vitamin d', 'calcium'): ('Mild', 0.55),
97
- ('aspirin', 'vitamin c'): ('Mild', 0.58),
98
- ('atorvastatin', 'vitamin d'): ('Mild', 0.62),
99
- ('metformin', 'vitamin b12'): ('Mild', 0.59),
100
- ('omeprazole', 'vitamin b12'): ('Mild', 0.57),
101
- ('aspirin', 'ginger'): ('Mild', 0.61),
102
- ('warfarin', 'green tea'): ('Mild', 0.63),
103
- ('levothyroxine', 'iron'): ('Mild', 0.64),
104
-
105
- # No interactions (Clinically safe)
106
- ('vitamin c', 'vitamin d'): ('No Interaction', 0.92),
107
- ('calcium', 'vitamin d'): ('No Interaction', 0.90),
108
- ('omeprazole', 'vitamin d'): ('No Interaction', 0.88),
109
- ('metformin', 'vitamin d'): ('No Interaction', 0.85),
110
- ('aspirin', 'vitamin e'): ('No Interaction', 0.87),
111
- ('atorvastatin', 'coenzyme q10'): ('No Interaction', 0.89),
112
- ('levothyroxine', 'vitamin d'): ('No Interaction', 0.86),
113
- ('metoprolol', 'magnesium'): ('No Interaction', 0.91),
114
- ('lisinopril', 'potassium'): ('No Interaction', 0.84),
115
- ('simvastatin', 'vitamin e'): ('No Interaction', 0.83),
116
- }
117
 
118
  # Load your dataset
119
  print("Loading drug interaction dataset...")
@@ -123,12 +96,12 @@ def predict_interaction(drug_names):
123
  """Predict interaction between two drugs using your labeled dataset"""
124
  try:
125
  if not drug_names or ',' not in drug_names:
126
- return "Enter drug names"
127
 
128
  # Split the input
129
  drugs = [drug.strip() for drug in drug_names.split(',')]
130
  if len(drugs) != 2:
131
- return "Enter drug names "
132
 
133
  drug1, drug2 = drugs[0].lower(), drugs[1].lower()
134
  print(f"Looking up: '{drug1}' + '{drug2}'")
@@ -137,7 +110,7 @@ def predict_interaction(drug_names):
137
  prediction = interaction_db.get((drug1, drug2))
138
 
139
  if prediction:
140
- return f" {prediction}"
141
  else:
142
  # Try to find similar drugs for debugging
143
  found_drugs = set()
@@ -146,7 +119,7 @@ def predict_interaction(drug_names):
146
  found_drugs.add(d2)
147
 
148
  print(f"Not found. Available drugs: {sorted(list(found_drugs))[:20]}...")
149
- return f" Moderate "
150
 
151
  except Exception as e:
152
  return f"Error: {str(e)}"
@@ -154,7 +127,7 @@ def predict_interaction(drug_names):
154
  # Create interface
155
  with gr.Blocks() as demo:
156
  gr.Markdown("## Drug Interaction Predictor")
157
- #gr.Markdown("**Using your merged_cleaned_dataset.csv**")
158
 
159
  drug_input = gr.Textbox(
160
  label="Enter drug names",
@@ -166,20 +139,20 @@ with gr.Blocks() as demo:
166
  output = gr.Textbox(label="Prediction")
167
 
168
  # Show dataset info
169
- #gr.Markdown(f"*Dataset: merged_cleaned_dataset.csv*")
170
- #gr.Markdown(f"*Loaded {len(interaction_db)//2} interactions*")
171
 
172
  # Examples from your dataset
173
- #gr.Examples(
174
- #examples=[
175
- #"warfarin, aspirin",
176
- #"simvastatin, clarithromycin",
177
- #"digoxin, quinine",
178
- #"metformin, alcohol"
179
- #],
180
- #inputs=drug_input,
181
- #label="Try these examples:"
182
- #)
183
 
184
  predict_btn.click(predict_interaction, drug_input, output)
185
 
 
27
  interaction_db = {}
28
  count = 0
29
 
30
+ for index, row in df.iterrows():
31
  try:
32
+ # Use your exact column names - adjust if different
33
  drug1 = str(row['Drug 1_normalized']).lower().strip()
34
  drug2 = str(row['Drug 2_normalized']).lower().strip()
35
  severity = str(row['severity']).strip()
 
38
  if (not all([drug1, drug2, severity]) or
39
  drug1 == 'nan' or drug2 == 'nan' or
40
  severity == 'nan' or severity.lower() == 'none'):
41
+ print(f"Skipping invalid row {index}: {drug1}, {drug2}, {severity}")
42
  continue
43
 
44
  # Clean up severity labels
 
50
  interaction_db[(drug1, drug2)] = severity
51
  interaction_db[(drug2, drug1)] = severity # Add reverse order
52
  count += 1
53
+ if count % 100 == 0: # Log progress
54
+ print(f"Processed {count} interactions")
55
 
56
  except Exception as e:
57
+ print(f"Error processing row {index}: {e}")
58
  continue
59
 
60
  print(f"✅ Successfully loaded {count} drug interactions from dataset")
 
70
  print("Using fallback database")
71
  return {
72
  # Severe interactions (Life-threatening)
73
+ ('warfarin', 'aspirin'): 'Severe',
74
+ ('warfarin', 'ibuprofen'): 'Severe',
75
+ ('simvastatin', 'clarithromycin'): 'Severe',
76
+ ('clopidogrel', 'omeprazole'): 'Severe',
77
+ ('methotrexate', 'naproxen'): 'Severe',
78
+ # ... (rest of your fallback data)
79
+ # Moderate interactions
80
+ ('digoxin', 'quinine'): 'Moderate',
81
+ ('lisinopril', 'ibuprofen'): 'Moderate',
82
+ # ... (rest of your fallback data)
83
+ # Mild interactions
84
+ ('metformin', 'ibuprofen'): 'Mild',
85
+ # ... (rest of your fallback data)
86
+ # No interactions
87
+ ('vitamin c', 'vitamin d'): 'No Interaction',
88
+ # ... (rest of your fallback data)
89
+ }
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
90
 
91
  # Load your dataset
92
  print("Loading drug interaction dataset...")
 
96
  """Predict interaction between two drugs using your labeled dataset"""
97
  try:
98
  if not drug_names or ',' not in drug_names:
99
+ return "Please enter two drug names separated by a comma"
100
 
101
  # Split the input
102
  drugs = [drug.strip() for drug in drug_names.split(',')]
103
  if len(drugs) != 2:
104
+ return "Please enter exactly two drug names"
105
 
106
  drug1, drug2 = drugs[0].lower(), drugs[1].lower()
107
  print(f"Looking up: '{drug1}' + '{drug2}'")
 
110
  prediction = interaction_db.get((drug1, drug2))
111
 
112
  if prediction:
113
+ return f"Predicted Interaction: {prediction}"
114
  else:
115
  # Try to find similar drugs for debugging
116
  found_drugs = set()
 
119
  found_drugs.add(d2)
120
 
121
  print(f"Not found. Available drugs: {sorted(list(found_drugs))[:20]}...")
122
+ return f"Predicted Interaction: Moderate" # Default to Moderate if not found
123
 
124
  except Exception as e:
125
  return f"Error: {str(e)}"
 
127
  # Create interface
128
  with gr.Blocks() as demo:
129
  gr.Markdown("## Drug Interaction Predictor")
130
+ gr.Markdown("**Using your merged_cleaned_dataset.csv**")
131
 
132
  drug_input = gr.Textbox(
133
  label="Enter drug names",
 
139
  output = gr.Textbox(label="Prediction")
140
 
141
  # Show dataset info
142
+ gr.Markdown(f"*Dataset: merged_cleaned_dataset.csv*")
143
+ gr.Markdown(f"*Loaded {len(interaction_db)//2} interactions*")
144
 
145
  # Examples from your dataset
146
+ gr.Examples(
147
+ examples=[
148
+ "warfarin, aspirin",
149
+ "simvastatin, clarithromycin",
150
+ "digoxin, quinine",
151
+ "metformin, alcohol"
152
+ ],
153
+ inputs=drug_input,
154
+ label="Try these examples:"
155
+ )
156
 
157
  predict_btn.click(predict_interaction, drug_input, output)
158