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title: Biological Uncertainty Stack
emoji: 🧬
colorFrom: blue
colorTo: indigo
sdk: static
app_file: index.html
pinned: false
license: cc-by-nc-4.0
short_description: Genomic uncertainty provenance map
tags:
- genomics
- GRCh38
- biological-uncertainty
- provenance
- uncertainty-governance
- systems-integrity
- HIR
- OAM
---
# Biological Uncertainty Stack
Biological Uncertainty Stack is a public HIR/OAM architecture map for genomic uncertainty, GRCh38 reference limits, provenance gates, measurement failure, and hard blocks against hidden positive evidence.
This Space uses the **Primordial DNA Layer · GRCh38 First-Pass Architecture Plan v0.1** as its source direction. It treats GRCh38 / GRCh38.p14 as Source Layer 1: an initial baseline reference frame for first-pass feature typing and uncertainty mapping, not a complete model of human diversity and not a final biological authority.
## Search target / source file
```text
Primordial_DNA_GRCh38_First_Pass_Architecture_Plan_v0.1.html
```
## Non-negotiable invariant
Unknown biology may preserve possibility space. Untrusted data may invalidate the comparison. Neither may be converted into hidden positive evidence.
Biological unresolvedness does not equal measurement/provenance unresolvedness. These categories must remain separate throughout all schemas, scoring, and downstream layers.
## Boundary
This is a bounded architecture and public review prototype.
It is not clinical advice, diagnosis, treatment guidance, identity proof, family-relation proof, forensic conclusion, ancestry result, genetic counseling, or validated genomic-comparison software.
GRCh38 is used as a reference frame only. All genomic inferences beyond declared evidence limits are explicitly blocked by the HIR rule set.
Structural correspondence, not ontological equivalence.
## Ecosystem position
This Space is part of the broader Primordial Code Ecosystem.
Parent hub:
https://huggingface.co/spaces/HirModel/primordial-code-ecosystem
Collection:
https://huggingface.co/collections/HirModel/primordial-code-ecosystem
This module is the biological-uncertainty and genomic provenance branch of the HIR/OAM life-first systems-integrity architecture.
## Ecosystem position
This Space is part of the broader Primordial Code Ecosystem.
Parent hub:
https://huggingface.co/spaces/HirModel/primordial-code-ecosystem
This module is one bounded branch of the HIR/OAM life-first systems-integrity architecture. |