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README.md

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-title: README
-emoji: 💻
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-# 🔬 K R&D Lab — Interactive Research Environments
-
-**Author:** Oksana Kolisnyk · [KOSATIKS GROUP](https://kosatiks-group.pp.ua)
-
-K R&D Lab is organized across three connected spheres:
-
-- `SCIENCE` for domain research questions
-- `ENTREPRENEURSHIP` for opportunity, market, ecosystem, and public-case work
-- `TECHNOLOGY` for reusable tooling, scoring, dashboards, and infrastructure
-
-## Choose your environment
-
-| Environment | Best for | Link |
-| --- | --- | --- |
-| 🧪 Learning Playground | Simulated exploration, student-friendly demos, safe first-pass testing | [Launch Playground](https://huggingface.co/spaces/K-RnD-Lab/Learning-Playground_03-2026) |
-| 🔬 Cancer Research Suite | Research-gap discovery, live biomedical lookups, more serious exploration | [Launch Research Suite](https://huggingface.co/spaces/K-RnD-Lab/Cancer-Research-Suite_03-2026) |
-| 🗂️ GitHub sphere repos | Full structure, reports, notebooks, README maps, and study scaffolds | [Open GitHub org](https://github.com/K-RnD-Lab) |
-
-> Both environments are free for academic use.
->
-> For commercial licensing or custom deployments, contact: [kosatiks.group@gmail.com](mailto:kosatiks.group@gmail.com)
-
-## Three Research Spheres
-
-| Sphere | Focus | Main repo |
-| --- | --- | --- |
-| 🧪 SCIENCE | Biology, medicine, plant science, ecology, chemistry, cognition, and longitudinal human-pattern research | [SPHERE-I-SCIENCE](https://github.com/K-RnD-Lab/SPHERE-I-SCIENCE) |
-| 🚀 ENTREPRENEURSHIP | Venture design, market intelligence, ecosystem mapping, and visible public cases | [SPHERE-II-ENTREPRENEURSHIP](https://github.com/K-RnD-Lab/SPHERE-II-ENTREPRENEURSHIP) |
-| 💻 TECHNOLOGY | Reusable research tools, reproducibility systems, dashboards, and open infrastructure | [SPHERE-III-TECHNOLOGY](https://github.com/K-RnD-Lab/SPHERE-III-TECHNOLOGY) |
-
-## Science Focus Today
-
-The strongest active density is currently in:
-
-- `S1` Biomedical & Oncology
-- `S7` K Life OS
-
-Current `S1` conference-aligned expertise includes:
-
-- nucleic-acid therapeutics
-- bioinformatics and AI in biomedical research
-- biomarkers and molecular diagnostics
-
-Future expansion areas, when they become repeated research programs rather than one-off labels:
-
-- biologics and antibody engineering
-- gene editing and functional therapeutics
-- cell therapies and translational platforms
-- structural biology and molecular design
-
-## How The Layers Work
-
-- `GitHub` is the source of truth for study structure, reports, notebooks, and research maps.
-- `Hugging Face Spaces` provide the interactive app layer.
-- The app layer is periodically mirrored back into GitHub for audit and sync.
-
-## Quick Links
-
-- [K-RnD-Lab GitHub Organization](https://github.com/K-RnD-Lab)
-- [K-RnD-Lab Hugging Face Organization](https://huggingface.co/K-RnD-Lab)
-- [SPHERE-I-SCIENCE](https://github.com/K-RnD-Lab/SPHERE-I-SCIENCE)
-- [SPHERE-II-ENTREPRENEURSHIP](https://github.com/K-RnD-Lab/SPHERE-II-ENTREPRENEURSHIP)
-- [SPHERE-III-TECHNOLOGY](https://github.com/K-RnD-Lab/SPHERE-III-TECHNOLOGY)
-- [Cross-Sphere Study Registry](https://github.com/K-RnD-Lab/SPHERE-III-TECHNOLOGY/tree/main/T3%20-%20Dashboards%2C%20Interfaces%20%26%20Open%20Infrastructure/T3-R1%20-%20Dashboard%20Templates%20%26%20Public%20Interfaces/R1a-study-registry-dashboard-template)
-- [Live Study Registry Space](https://huggingface.co/spaces/K-RnD-Lab/Study-Registry_04-2026)
-
-## Disclaimer
-
-All computational models are research-grade and hypothesis-generating. Simulated outputs, exploratory scores, and interface demos require real validation before scientific, clinical, agricultural, educational, or commercial use.
+---
+title: README
+emoji: 💻
+colorFrom: green
+colorTo: red
+sdk: static
+pinned: true
+---
+
+# [K-RnD Lab] — Interactive Research Environments
+
+**Author:** Oksana Kolisnyk · [KOSATIKS GROUP](https://kosatiks-group.pp.ua)
+
+[K-RnD Lab] is organized across three connected spheres:
+
+- `SCIENCE` — domain research questions
+- `ENTREPRENEURSHIP` — opportunity, market, ecosystem work
+- `TECHNOLOGY` — reusable tooling, scoring, dashboards, infrastructure
+
+## Interactive Spaces
+
+| Space | Sphere | Description |
+|---|---|---|
+| [Learning Playground](https://huggingface.co/spaces/K-RnD-Lab/Learning-Playground_03-2026) | S | Simulated exploration, student demos |
+| [Cancer Research Suite](https://huggingface.co/spaces/K-RnD-Lab/Cancer-Research-Suite_03-2026) | S1 | Research-gap discovery, biomedical lookups |
+| [PHYLO brca2-mirna](https://huggingface.co/spaces/K-RnD-Lab/PHYLO-03_2026-01_A1-brca2-mirna) | S1 | Phylogenetic analysis |
+| [Study Registry](https://huggingface.co/spaces/K-RnD-Lab/Study-Registry_04-2026) | T3 | Cross-sphere study registry |
+| [bioscore](https://huggingface.co/spaces/K-RnD-Lab/bioscore) | T1 | Biomedical scoring demo |
+
+## Python Packages (pip install)
+
+| Package | Sphere | PyPI |
+|---|---|---|
+| [bioscore](https://pypi.org/project/bioscore/) | T1 | Reproducibility, data quality, model readiness |
+| [set-method](https://github.com/K-RnD-Lab/SPHERE-III-TECHNOLOGY) | T2 | SET classification, scoring, recommendation |
+| [studyreg](https://pypi.org/project/studyreg/) | T3 | Study pre-registration, search, validation |
+
+## Datasets & Models
+
+| Repo | Type | Description |
+|---|---|---|
+| [studyreg-sample-dataset](https://huggingface.co/datasets/K-RnD-Lab/studyreg-sample-dataset) | Dataset | Sample studies for studyreg |
+| [set-method](https://huggingface.co/K-RnD-Lab/set-method) | Model | SET framework reference |
+
+## Three Spheres on GitHub
+
+| Sphere | Repo |
+|---|---|
+| SCIENCE | [SPHERE-I-SCIENCE](https://github.com/K-RnD-Lab/SPHERE-I-SCIENCE) |
+| ENTREPRENEURSHIP | [SPHERE-II-ENTREPRENEURSHIP](https://github.com/K-RnD-Lab/SPHERE-II-ENTREPRENEURSHIP) |
+| TECHNOLOGY | [SPHERE-III-TECHNOLOGY](https://github.com/K-RnD-Lab/SPHERE-III-TECHNOLOGY) |
+
+## Disclaimer
+
+All computational models are research-grade and hypothesis-generating. Simulated outputs require real validation before scientific, clinical, or commercial use.