app.py

from fastapi import FastAPI, Body
from pydantic import BaseModel
from transformers import AutoTokenizer, BigBirdForSequenceClassification
from scipy.special import softmax
import torch

# Import AJCC API logic
from ajcc_api import stage_cancer

# Initialize FastAPI
app = FastAPI(title="TNM + AJCC Endpoint", version="2.0")

# Models (TNM) from Hugging Face
MODEL_T = "jkefeli/CancerStage_Classifier_T"
MODEL_N = "jkefeli/CancerStage_Classifier_N"
MODEL_M = "jkefeli/CancerStage_Classifier_M"

# Load tokenizer once
tokenizer = AutoTokenizer.from_pretrained("yikuan8/Clinical-BigBird")

# Load models once
model_T = BigBirdForSequenceClassification.from_pretrained(MODEL_T)
model_N = BigBirdForSequenceClassification.from_pretrained(MODEL_N)
model_M = BigBirdForSequenceClassification.from_pretrained(MODEL_M)

class Report(BaseModel):
    text: str
    cancer_type: str = "colon"   # default, you can change it (breast, lung, etc.)

def predict_class(text, model):
    inputs = tokenizer(text, return_tensors="pt", truncation=True, padding=True, max_length=2048)
    with torch.no_grad():
        outputs = model(**inputs)
        probs = softmax(outputs.logits.numpy(), axis=1)
        pred_class = probs.argmax(axis=1)[0]
    return int(pred_class)

@app.get("/")
def health_check():
    return {"status": "running", "models": {"T": MODEL_T, "N": MODEL_N, "M": MODEL_M}}

@app.post("/predict_full")
def predict_full(report: Report = Body(...)):
    text = report.text
    cancer = report.cancer_type.lower()

    try:
        # 1) Predict numeric TNM classes
        t_class = predict_class(text, model_T)
        n_class = predict_class(text, model_N)
        m_class = predict_class(text, model_M)

        # 2) Convert numeric classes → TNM labels
        T = f"T{t_class}"
        N = f"N{n_class}"
        M = f"M{m_class}"

        # 3) Compute AJCC Stage
        stage = stage_cancer(cancer_type=cancer, T=T, N=N, M=M)

        return {
            "input": text,
            "TNM_prediction": {"T": T, "N": N, "M": M},
            "AJCC_stage": stage,
            "cancer_type_used": cancer
        }

    except Exception as e:
        return {"error": str(e)}