FunGO v2.0 backend
Browse files- README.md +33 -6
- hf_README.md +0 -41
README.md
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---
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title: FunGO
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emoji:
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colorFrom:
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sdk: gradio
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sdk_version:
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app_file: app.py
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pinned: false
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license: mit
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short_description:
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---
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---
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title: FunGO
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emoji: π§¬
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colorFrom: blue
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colorTo: green
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sdk: gradio
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sdk_version: 4.44.0
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app_file: app.py
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pinned: false
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license: mit
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short_description: Protein Function Prediction using ESM2 + XGBoost
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---
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# FunGO β Protein Function Prediction
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**Beyond Prediction β Understanding Function.**
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FunGO predicts Gene Ontology (GO) terms for protein sequences using:
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- **ESM2-t36-3B** β protein language model embeddings (layers 30β35)
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- **XGBoost classifiers** β 4,133 GO-term specific models
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- **Evidence-tiered filtering** β Strong / Moderate / Indicative
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## Evidence Tiers
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| Tier | IA Weight | Confidence | Description |
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|------|-----------|------------|-------------|
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| Strong Evidence | > 5.0 | β₯ 0.30 | Highly specific GO term |
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| Moderate Evidence | > 2.0 | β₯ 0.50 | Moderately specific term |
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| Indicative | > 1.0 | β₯ 0.65 | Lower specificity, high confidence |
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## Ontologies Covered
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- **MFO** β Molecular Function
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- **BPO** β Biological Process
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- **CCO** β Cellular Component
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## Development Team
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- **Dr. Beenish Maqsood** β Principal Investigator, School of Biochemistry and Biotechnology, University of the Punjab
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- **Dr. Naeem Mahmood** β Co-Supervisor, School of Biochemistry and Biotechnology, University of the Punjab
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- **Muteeba Azhar** β Lead Developer, MS Researcher, University of the Punjab
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hf_README.md
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@@ -1,41 +0,0 @@
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-
---
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-
title: FunGO
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-
emoji: π§¬
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-
colorFrom: blue
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-
colorTo: green
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sdk: gradio
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sdk_version: 4.44.0
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app_file: app.py
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pinned: false
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license: mit
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short_description: Protein Function Prediction using ESM2 + XGBoost
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---
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-
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# FunGO β Protein Function Prediction
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-
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**Beyond Prediction β Understanding Function.**
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-
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-
FunGO predicts Gene Ontology (GO) terms for protein sequences using:
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- **ESM2-t36-3B** β protein language model embeddings (layers 30β35)
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-
- **XGBoost classifiers** β 4,133 GO-term specific models
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-
- **Evidence-tiered filtering** β Strong / Moderate / Indicative
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-
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## Evidence Tiers
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| Tier | IA Weight | Confidence | Description |
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|------|-----------|------------|-------------|
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| Strong Evidence | > 5.0 | β₯ 0.30 | Highly specific GO term |
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| Moderate Evidence | > 2.0 | β₯ 0.50 | Moderately specific term |
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| Indicative | > 1.0 | β₯ 0.65 | Lower specificity, high confidence |
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-
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## Ontologies Covered
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- **MFO** β Molecular Function
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- **BPO** β Biological Process
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- **CCO** β Cellular Component
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## Development Team
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- **Dr. Beenish Maqsood** β Principal Investigator, School of Biochemistry and Biotechnology, University of the Punjab
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- **Dr. Naeem Mahmood** β Co-Supervisor, School of Biochemistry and Biotechnology, University of the Punjab
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- **Muteeba Azhar** β Lead Developer, MS Researcher, University of the Punjab
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