Muteeba commited on
Commit
e22292f
Β·
1 Parent(s): 5c389ab

FunGO v2.0 backend

Browse files
Files changed (2) hide show
  1. README.md +33 -6
  2. hf_README.md +0 -41
README.md CHANGED
@@ -1,14 +1,41 @@
1
  ---
2
  title: FunGO
3
- emoji: 🐒
4
- colorFrom: indigo
5
- colorTo: purple
6
  sdk: gradio
7
- sdk_version: 6.12.0
8
  app_file: app.py
9
  pinned: false
10
  license: mit
11
- short_description: Multi-label protein function prediction via Gene Ontology
12
  ---
13
 
14
- Check out the configuration reference at https://huggingface.co/docs/hub/spaces-config-reference
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
  ---
2
  title: FunGO
3
+ emoji: 🧬
4
+ colorFrom: blue
5
+ colorTo: green
6
  sdk: gradio
7
+ sdk_version: 4.44.0
8
  app_file: app.py
9
  pinned: false
10
  license: mit
11
+ short_description: Protein Function Prediction using ESM2 + XGBoost
12
  ---
13
 
14
+ # FunGO β€” Protein Function Prediction
15
+
16
+ **Beyond Prediction β€” Understanding Function.**
17
+
18
+ FunGO predicts Gene Ontology (GO) terms for protein sequences using:
19
+ - **ESM2-t36-3B** β€” protein language model embeddings (layers 30–35)
20
+ - **XGBoost classifiers** β€” 4,133 GO-term specific models
21
+ - **Evidence-tiered filtering** β€” Strong / Moderate / Indicative
22
+
23
+ ## Evidence Tiers
24
+
25
+ | Tier | IA Weight | Confidence | Description |
26
+ |------|-----------|------------|-------------|
27
+ | Strong Evidence | > 5.0 | β‰₯ 0.30 | Highly specific GO term |
28
+ | Moderate Evidence | > 2.0 | β‰₯ 0.50 | Moderately specific term |
29
+ | Indicative | > 1.0 | β‰₯ 0.65 | Lower specificity, high confidence |
30
+
31
+ ## Ontologies Covered
32
+
33
+ - **MFO** β€” Molecular Function
34
+ - **BPO** β€” Biological Process
35
+ - **CCO** β€” Cellular Component
36
+
37
+ ## Development Team
38
+
39
+ - **Dr. Beenish Maqsood** β€” Principal Investigator, School of Biochemistry and Biotechnology, University of the Punjab
40
+ - **Dr. Naeem Mahmood** β€” Co-Supervisor, School of Biochemistry and Biotechnology, University of the Punjab
41
+ - **Muteeba Azhar** β€” Lead Developer, MS Researcher, University of the Punjab
hf_README.md DELETED
@@ -1,41 +0,0 @@
1
- ---
2
- title: FunGO
3
- emoji: 🧬
4
- colorFrom: blue
5
- colorTo: green
6
- sdk: gradio
7
- sdk_version: 4.44.0
8
- app_file: app.py
9
- pinned: false
10
- license: mit
11
- short_description: Protein Function Prediction using ESM2 + XGBoost
12
- ---
13
-
14
- # FunGO β€” Protein Function Prediction
15
-
16
- **Beyond Prediction β€” Understanding Function.**
17
-
18
- FunGO predicts Gene Ontology (GO) terms for protein sequences using:
19
- - **ESM2-t36-3B** β€” protein language model embeddings (layers 30–35)
20
- - **XGBoost classifiers** β€” 4,133 GO-term specific models
21
- - **Evidence-tiered filtering** β€” Strong / Moderate / Indicative
22
-
23
- ## Evidence Tiers
24
-
25
- | Tier | IA Weight | Confidence | Description |
26
- |------|-----------|------------|-------------|
27
- | Strong Evidence | > 5.0 | β‰₯ 0.30 | Highly specific GO term |
28
- | Moderate Evidence | > 2.0 | β‰₯ 0.50 | Moderately specific term |
29
- | Indicative | > 1.0 | β‰₯ 0.65 | Lower specificity, high confidence |
30
-
31
- ## Ontologies Covered
32
-
33
- - **MFO** β€” Molecular Function
34
- - **BPO** β€” Biological Process
35
- - **CCO** β€” Cellular Component
36
-
37
- ## Development Team
38
-
39
- - **Dr. Beenish Maqsood** β€” Principal Investigator, School of Biochemistry and Biotechnology, University of the Punjab
40
- - **Dr. Naeem Mahmood** β€” Co-Supervisor, School of Biochemistry and Biotechnology, University of the Punjab
41
- - **Muteeba Azhar** β€” Lead Developer, MS Researcher, University of the Punjab