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app.py
CHANGED
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@@ -1,7 +1,14 @@
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import gradio as gr
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import os
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import requests
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from groq import Groq
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GROQ_KEY = os.environ.get("GROQ_API_KEY", "")
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@@ -13,176 +20,20 @@ KNOWHOW = ("SJSU CardioLab: "
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"Equipment: Heska HT5 hematology analyzer time-resolved PIV Tygon tubing Arduino Uno.")
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CSS = """
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}
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.
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}
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/* HEADER */
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.main-header {
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background: linear-gradient(135deg, #1a237e 0%, #b71c1c 100%);
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border-bottom: 3px solid #e63946;
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padding: 30px 20px;
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text-align: center;
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margin-bottom: 0;
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}
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/* TABS - ALWAYS VISIBLE */
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.tab-nav {
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background: #ffffff !important;
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border-bottom: 2px solid #e2e8f0 !important;
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padding: 0 10px !important;
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display: flex !important;
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gap: 5px !important;
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overflow-x: auto !important;
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}
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.tab-nav button {
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background: #f7fafc !important;
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color: #2d3748 !important;
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border: 1px solid #e2e8f0 !important;
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border-radius: 8px 8px 0 0 !important;
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padding: 12px 20px !important;
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font-size: 0.9em !important;
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font-weight: 600 !important;
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cursor: pointer !important;
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transition: all 0.2s !important;
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white-space: nowrap !important;
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margin-top: 8px !important;
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}
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.tab-nav button:hover {
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background: #ebf4ff !important;
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color: #1a237e !important;
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border-color: #4361ee !important;
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}
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.tab-nav button.selected {
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background: linear-gradient(135deg, #e63946, #c1121f) !important;
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color: #ffffff !important;
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border-color: #e63946 !important;
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font-weight: 700 !important;
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}
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/* CONTENT AREA */
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.tabitem {
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background: #ffffff !important;
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padding: 20px !important;
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border: 1px solid #e2e8f0 !important;
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border-top: none !important;
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}
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/* INPUTS */
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textarea, input[type=number], input[type=text] {
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background: #f7fafc !important;
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color: #1a202c !important;
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border: 1px solid #cbd5e0 !important;
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border-radius: 8px !important;
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font-size: 0.95em !important;
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}
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textarea:focus, input:focus {
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border-color: #e63946 !important;
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outline: none !important;
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}
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textarea::placeholder {
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color: #a0aec0 !important;
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}
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/* BUTTONS */
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button.primary, .btn-primary {
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background: linear-gradient(135deg, #e63946 0%, #c1121f 100%) !important;
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color: white !important;
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border: none !important;
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border-radius: 8px !important;
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font-weight: 700 !important;
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padding: 12px 24px !important;
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font-size: 0.95em !important;
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cursor: pointer !important;
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transition: transform 0.1s !important;
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}
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button.primary:hover {
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transform: translateY(-1px) !important;
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box-shadow: 0 4px 15px rgba(230, 57, 70, 0.4) !important;
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}
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button.secondary {
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background: #edf2f7 !important;
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color: #4a5568 !important;
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border: 1px solid #cbd5e0 !important;
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border-radius: 8px !important;
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font-weight: 600 !important;
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}
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/* LABELS */
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label span, label, .label-wrap span {
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color: #2b6cb0 !important;
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font-weight: 600 !important;
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font-size: 0.85em !important;
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text-transform: uppercase !important;
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letter-spacing: 0.5px !important;
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}
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/* MARKDOWN TEXT */
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.md h1, .md h2, .md h3 { color: #ffffff !important; }
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.md p, .md li { color: #a0b3d6 !important; }
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/* CHATBOT */
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.chatbot {
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background: #0a1628 !important;
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border: 1px solid #1e3a6e !important;
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border-radius: 12px !important;
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}
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.message.user {
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background: linear-gradient(135deg, #e63946, #c1121f) !important;
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color: #ffffff !important;
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border-radius: 12px 12px 4px 12px !important;
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}
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.message.bot {
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background: #ebf4ff !important;
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color: #1a202c !important;
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border: 1px solid #bee3f8 !important;
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border-radius: 12px 12px 12px 4px !important;
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}
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/* RESULT BOXES */
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.gr-box, .block {
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background: #ffffff !important;
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border: 1px solid #e2e8f0 !important;
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border-radius: 12px !important;
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}
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/* NUMBERS */
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input[type=number] {
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color: #7eb8f7 !important;
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font-size: 1.1em !important;
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font-weight: 600 !important;
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}
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/* INFO TEXT */
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.info {
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color: #5a7aaa !important;
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font-size: 0.8em !important;
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}
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/* SCROLLBAR */
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::-webkit-scrollbar { width: 6px; }
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::-webkit-scrollbar-track { background: #f7fafc; }
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::-webkit-scrollbar-thumb { background: #cbd5e0; border-radius: 3px; }
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"""
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def get_pubmed(query, n=5):
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try:
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client = Groq(api_key=GROQ_KEY)
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pubmed = get_pubmed(message, n=3)
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msgs = [{"role":"system","content":system_msg}]
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for item in history:
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if isinstance(item, dict):
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msgs.append({"role":item["role"],"content":item["content"]})
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return history
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def generate_diagram(topic):
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def piv_tool(velocity, shear, hr):
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v = "HIGH - stenosis risk" if float(velocity)>2.0 else "NORMAL"
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def tgt_tool(tat,pf12,hemo,platelets,time):
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risk=sum([float(tat)>15,float(pf12)>2.0,float(hemo)>50,float(platelets)<150])
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r="HIGH THROMBOGENIC RISK" if risk>=3 else "MODERATE RISK" if risk>=2 else "LOW RISK"
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return ("TGT BLOOD ANALYSIS"+chr(10)+
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"ββββββββββββββββββββ"+chr(10)+
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"Time: "+str(time)+" min"+chr(10)+
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"TAT: "+str(tat)+" β "+("HIGH" if float(tat)>15 else "NORMAL")+chr(10)+
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"PF1.2: "+str(pf12)+" β "+("HIGH" if float(pf12)>2.0 else "NORMAL")+chr(10)+
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"Hemoglobin: "+str(hemo)+" β "+("HIGH" if float(hemo)>50 else "NORMAL")+chr(10)+
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"Platelets: "+str(platelets)+" β "+("LOW" if float(platelets)<150 else "NORMAL")+chr(10)+
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"ββββββββββββββββββββ"+chr(10)+
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"OVERALL: "+r)
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def upad_tool(r,g,b):
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c=max(0,round(0.02*(float(r)-float(b))-0.5,2))
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elif c<3.0: s="Stage 2 CKD"
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elif c<6.0: s="Stage 3-4 CKD"
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else: s="Stage 5 CKD - Kidney Failure"
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return ("uPAD CKD ANALYSIS"+chr(10)+
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"
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"
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"
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"Creatinine: "+str(c)+" mg/dL"+chr(10)+
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"ββββββββββββββββββββ"+chr(10)+
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"CKD STAGE: "+s+chr(10)+
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"Confirm with: Heska Element HT5")
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with gr.Blocks(title="CardioLab AI", css=CSS) as demo:
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gr.HTML("""
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<div class="main-header">
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<div style="font-size:2.8em;
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β€οΈ CardioLab AI
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</div>
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</div>
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with gr.Tab("π¬ Chat"):
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chatbot = gr.Chatbot(label="", height=450)
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with gr.Row():
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msg_box = gr.Textbox(
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placeholder="Ask anything about CardioLab research...",
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label="",
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lines=2,
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scale=4
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)
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with gr.Column(scale=1, min_width=100):
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send_btn = gr.Button("Send β€", variant="primary")
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clear_btn = gr.Button("Clear", variant="secondary")
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with gr.Tab("π Papers"):
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gr.Markdown("### Search latest research papers with verified working links")
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with gr.Row():
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search_input = gr.Textbox(
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placeholder="e.g. mechanical heart valve thrombogenicity",
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label="Research Topic",
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scale=4
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)
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search_btn = gr.Button("Search β€", variant="primary", scale=1)
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search_output = gr.Textbox(label="Results β Verified Links Only", lines=18)
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search_btn.click(quick_search, inputs=search_input, outputs=search_output)
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search_input.submit(quick_search, inputs=search_input, outputs=search_output)
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gr.Markdown("**Try:** `
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with gr.Tab("π¨ Diagrams"):
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gr.Markdown("### Generate
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with gr.Row():
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diagram_input = gr.Textbox(
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placeholder="e.g. Mock Circulatory Loop with PIV system",
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label="What to diagram",
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scale=4
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)
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diagram_btn = gr.Button("Generate β€", variant="primary", scale=1)
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diagram_output = gr.
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diagram_btn.click(generate_diagram, inputs=diagram_input, outputs=diagram_output)
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gr.Markdown("**Try:** `TGT
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with gr.Tab("π PIV"):
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gr.Markdown("### Analyze Particle Image Velocimetry data from Mock Circulatory Loop")
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with gr.Row():
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with gr.Column():
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v=gr.Number(label="Max Velocity (m/s)", value=1.8, info="Normal
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s=gr.Number(label="Wall Shear Stress (Pa)", value=6.5, info="Normal: below 5 Pa")
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h=gr.Number(label="Heart Rate (bpm)", value=72, info="Normal: 60
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piv_btn = gr.Button("Analyze PIV
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with gr.Column():
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piv_out=gr.Textbox(label="Analysis Result", lines=8)
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piv_btn.click(piv_tool, inputs=[v,s,h], outputs=piv_out)
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@@ -404,9 +387,9 @@ with gr.Blocks(title="CardioLab AI", css=CSS) as demo:
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t1=gr.Number(label="TAT (ng/mL)", value=18, info="Normal: below 8")
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t2=gr.Number(label="PF1.2 (nmol/L)", value=2.5, info="Normal: below 2.0")
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t3=gr.Number(label="Free Hemoglobin (mg/L)", value=60, info="Normal: below 20")
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t4=gr.Number(label="Platelet Count
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t5=gr.Number(label="Time (minutes)", value=40)
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tgt_btn = gr.Button("Analyze TGT
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with gr.Column():
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out2=gr.Textbox(label="Analysis Result", lines=12)
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tgt_btn.click(tgt_tool, inputs=[t1,t2,t3,t4,t5], outputs=out2)
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gr.Markdown("### Analyze uPAD colorimetric result using Jaffe Reaction for CKD diagnosis")
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with gr.Row():
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with gr.Column():
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gr.
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b=gr.Number(label="B (Blue)", value=80, info="Range: 0 - 255")
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| 422 |
upad_btn = gr.Button("Analyze uPAD β€", variant="primary")
|
| 423 |
with gr.Column():
|
| 424 |
out3=gr.Textbox(label="CKD Analysis Result", lines=10)
|
|
|
|
| 1 |
import gradio as gr
|
| 2 |
import os
|
| 3 |
import requests
|
| 4 |
+
import matplotlib
|
| 5 |
+
matplotlib.use("Agg")
|
| 6 |
+
import matplotlib.pyplot as plt
|
| 7 |
+
import matplotlib.patches as mpatches
|
| 8 |
+
import numpy as np
|
| 9 |
from groq import Groq
|
| 10 |
+
import io
|
| 11 |
+
from PIL import Image
|
| 12 |
|
| 13 |
GROQ_KEY = os.environ.get("GROQ_API_KEY", "")
|
| 14 |
|
|
|
|
| 20 |
"Equipment: Heska HT5 hematology analyzer time-resolved PIV Tygon tubing Arduino Uno.")
|
| 21 |
|
| 22 |
CSS = """
|
| 23 |
+
body, .gradio-container { background: #f0f4f8 !important; color: #1a202c !important; }
|
| 24 |
+
.tab-nav { background: #ffffff !important; border-bottom: 2px solid #e2e8f0 !important; padding: 0 10px !important; }
|
| 25 |
+
.tab-nav button { background: #f7fafc !important; color: #2d3748 !important; border: 1px solid #e2e8f0 !important; border-radius: 8px 8px 0 0 !important; padding: 12px 18px !important; font-size: 0.9em !important; font-weight: 600 !important; margin-top: 6px !important; transition: all 0.2s !important; }
|
| 26 |
+
.tab-nav button:hover { background: #ebf4ff !important; color: #1a237e !important; border-color: #4361ee !important; }
|
| 27 |
+
.tab-nav button.selected { background: linear-gradient(135deg, #e63946, #c1121f) !important; color: #ffffff !important; border-color: #e63946 !important; font-weight: 700 !important; }
|
| 28 |
+
.tabitem { background: #ffffff !important; padding: 20px !important; border: 1px solid #e2e8f0 !important; border-top: none !important; border-radius: 0 0 12px 12px !important; }
|
| 29 |
+
.main-header { background: linear-gradient(135deg, #1a237e 0%, #b71c1c 100%); border-bottom: 3px solid #e63946; padding: 25px 20px; text-align: center; border-radius: 12px 12px 0 0; }
|
| 30 |
+
textarea, input[type=number], input[type=text] { background: #f7fafc !important; color: #1a202c !important; border: 1px solid #cbd5e0 !important; border-radius: 8px !important; }
|
| 31 |
+
textarea::placeholder { color: #a0aec0 !important; }
|
| 32 |
+
button.primary { background: linear-gradient(135deg, #e63946 0%, #c1121f 100%) !important; color: white !important; border: none !important; border-radius: 8px !important; font-weight: 700 !important; padding: 12px 24px !important; }
|
| 33 |
+
button.secondary { background: #edf2f7 !important; color: #4a5568 !important; border: 1px solid #cbd5e0 !important; border-radius: 8px !important; }
|
| 34 |
+
label span, .label-wrap span { color: #2b6cb0 !important; font-weight: 600 !important; font-size: 0.85em !important; text-transform: uppercase !important; }
|
| 35 |
+
.message.user { background: linear-gradient(135deg, #e63946, #c1121f) !important; color: white !important; border-radius: 12px 12px 4px 12px !important; }
|
| 36 |
+
.message.bot { background: #ebf4ff !important; color: #1a202c !important; border: 1px solid #bee3f8 !important; border-radius: 12px 12px 12px 4px !important; }
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|
| 37 |
"""
|
| 38 |
|
| 39 |
def get_pubmed(query, n=5):
|
|
|
|
| 79 |
try:
|
| 80 |
client = Groq(api_key=GROQ_KEY)
|
| 81 |
pubmed = get_pubmed(message, n=3)
|
| 82 |
+
msgs = [{"role":"system","content":"You are CardioLab AI assistant. Expert in MHV MCL PIV TGT uPAD CKD FSI. Remember full conversation. Never invent URLs. "+KNOWHOW}]
|
|
|
|
| 83 |
for item in history:
|
| 84 |
if isinstance(item, dict):
|
| 85 |
msgs.append({"role":item["role"],"content":item["content"]})
|
|
|
|
| 122 |
return history
|
| 123 |
|
| 124 |
def generate_diagram(topic):
|
| 125 |
+
topic_lower = topic.lower()
|
| 126 |
+
fig, ax = plt.subplots(1, 1, figsize=(12, 8))
|
| 127 |
+
ax.set_xlim(0, 12)
|
| 128 |
+
ax.set_ylim(0, 8)
|
| 129 |
+
ax.axis("off")
|
| 130 |
+
fig.patch.set_facecolor("#0d1b3e")
|
| 131 |
+
ax.set_facecolor("#0d1b3e")
|
| 132 |
+
|
| 133 |
+
if "tgt" in topic_lower or "thrombogen" in topic_lower:
|
| 134 |
+
ax.set_title("Thrombogenicity Tester (TGT) β SJSU CardioLab", color="white", fontsize=14, fontweight="bold", pad=15)
|
| 135 |
+
components = [
|
| 136 |
+
(1, 6, 2, 1, "#e63946", "Arduino Uno
|
| 137 |
+
(Controller)"),
|
| 138 |
+
(4, 6, 2, 1, "#4361ee", "Motor Driver"),
|
| 139 |
+
(7, 6, 2, 1, "#2ecc71", "Stepper Motor"),
|
| 140 |
+
(4, 3.5, 4, 2, "#1a2744", "Test Chamber
|
| 141 |
+
27mm SJM Regent MHV
|
| 142 |
+
(150mL Blood)"),
|
| 143 |
+
(1, 1, 2, 1, "#e67e22", "Heska HT5
|
| 144 |
+
Analyzer"),
|
| 145 |
+
(9, 1, 2, 1, "#9b59b6", "Data Logger"),
|
| 146 |
+
]
|
| 147 |
+
for x, y, w, h, color, label in components:
|
| 148 |
+
rect = mpatches.FancyBboxPatch((x, y), w, h, boxstyle="round,pad=0.1", facecolor=color, edgecolor="white", linewidth=2)
|
| 149 |
+
ax.add_patch(rect)
|
| 150 |
+
ax.text(x+w/2, y+h/2, label, ha="center", va="center", color="white", fontsize=8, fontweight="bold")
|
| 151 |
+
arrows = [(2, 6.5, 4, 6.5), (5, 6.5, 7, 6.5), (8, 6, 8, 5.5), (6, 3.5, 6, 2), (4, 4.5, 2, 2), (8, 3.5, 10, 2)]
|
| 152 |
+
for x1,y1,x2,y2 in arrows:
|
| 153 |
+
ax.annotate("", xy=(x2,y2), xytext=(x1,y1), arrowprops=dict(arrowstyle="->", color="#7eb8f7", lw=2))
|
| 154 |
+
labels = [(3, 7, "Signal"), (5.5, 7, "Power"), (8.5, 5.7, "Rotate"), (6.5, 2.8, "Sample"), (2.8, 3.5, "Analyze"), (9, 2.8, "Record")]
|
| 155 |
+
for x, y, t in labels:
|
| 156 |
+
ax.text(x, y, t, color="#a8b2d8", fontsize=7, ha="center")
|
| 157 |
+
times = ["0 min", "20 min", "40 min", "60 min"]
|
| 158 |
+
for i, t in enumerate(times):
|
| 159 |
+
ax.text(1+i*2.5, 0.5, t, color="#e63946", fontsize=8, ha="center", fontweight="bold")
|
| 160 |
+
ax.text(6, 0.5, "Blood Sampling Times", color="#7eb8f7", fontsize=8, ha="center")
|
| 161 |
+
|
| 162 |
+
elif "mcl" in topic_lower or "circulatory" in topic_lower or "piv" in topic_lower:
|
| 163 |
+
ax.set_title("Mock Circulatory Loop (MCL) + PIV System β SJSU CardioLab", color="white", fontsize=13, fontweight="bold", pad=15)
|
| 164 |
+
loop_x = [2, 4, 6, 8, 10, 10, 8, 6, 4, 2, 2]
|
| 165 |
+
loop_y = [4, 6, 6.5, 6, 4, 3, 2, 1.5, 2, 3, 4]
|
| 166 |
+
ax.plot(loop_x, loop_y, color="#4361ee", linewidth=4, label="Flow Loop")
|
| 167 |
+
components = [
|
| 168 |
+
(5, 5.8, 2, 0.8, "#e63946", "MHV Test Section
|
| 169 |
+
(Sylgard 184)"),
|
| 170 |
+
(1, 3.5, 1.5, 0.8, "#2ecc71", "Pump"),
|
| 171 |
+
(8.5, 3.5, 1.5, 0.8, "#e67e22", "Compliance
|
| 172 |
+
Chamber"),
|
| 173 |
+
(4.5, 1.2, 2, 0.8, "#9b59b6", "Reservoir"),
|
| 174 |
+
]
|
| 175 |
+
for x, y, w, h, color, label in components:
|
| 176 |
+
rect = mpatches.FancyBboxPatch((x, y), w, h, boxstyle="round,pad=0.1", facecolor=color, edgecolor="white", linewidth=2)
|
| 177 |
+
ax.add_patch(rect)
|
| 178 |
+
ax.text(x+w/2, y+h/2, label, ha="center", va="center", color="white", fontsize=7, fontweight="bold")
|
| 179 |
+
ax.annotate("", xy=(6, 7.5), xytext=(6, 6.5), arrowprops=dict(arrowstyle="->", color="#00ff88", lw=2))
|
| 180 |
+
ax.text(6, 7.7, "Green Laser (PIV)", color="#00ff88", fontsize=8, ha="center", fontweight="bold")
|
| 181 |
+
rect_laser = mpatches.FancyBboxPatch((5, 7.5), 2, 0.4, boxstyle="round,pad=0.05", facecolor="#00ff44", edgecolor="white", linewidth=1)
|
| 182 |
+
ax.add_patch(rect_laser)
|
| 183 |
+
ax.text(6, 7.7, "LASER", ha="center", va="center", color="black", fontsize=7, fontweight="bold")
|
| 184 |
+
rect_cam = mpatches.FancyBboxPatch((9.5, 5.5), 1.5, 0.8, boxstyle="round,pad=0.05", facecolor="#1a2744", edgecolor="#7eb8f7", linewidth=2)
|
| 185 |
+
ax.add_patch(rect_cam)
|
| 186 |
+
ax.text(10.25, 5.9, "Camera
|
| 187 |
+
(PIV)", ha="center", va="center", color="white", fontsize=7, fontweight="bold")
|
| 188 |
+
|
| 189 |
+
elif "upad" in topic_lower or "ckd" in topic_lower or "creatinine" in topic_lower:
|
| 190 |
+
ax.set_title("uPAD Fabrication and CKD Detection Flow β SJSU CardioLab", color="white", fontsize=13, fontweight="bold", pad=15)
|
| 191 |
+
steps = [
|
| 192 |
+
(0.5, 6, "#e63946", "1. Whatman
|
| 193 |
+
Paper"),
|
| 194 |
+
(2.5, 6, "#e67e22", "2. Wax
|
| 195 |
+
Printer"),
|
| 196 |
+
(4.5, 6, "#f1c40f", "3. Heat
|
| 197 |
+
120Β°C"),
|
| 198 |
+
(6.5, 6, "#2ecc71", "4. Add
|
| 199 |
+
Reagents"),
|
| 200 |
+
(8.5, 6, "#4361ee", "5. Apply
|
| 201 |
+
Sample"),
|
| 202 |
+
(10, 6, "#9b59b6", "6. Image
|
| 203 |
+
Analysis"),
|
| 204 |
+
]
|
| 205 |
+
for x, y, color, label in steps:
|
| 206 |
+
circle = plt.Circle((x+0.75, y+0.5), 0.7, color=color, zorder=5)
|
| 207 |
+
ax.add_patch(circle)
|
| 208 |
+
ax.text(x+0.75, y+0.5, label, ha="center", va="center", color="white", fontsize=7, fontweight="bold", zorder=6)
|
| 209 |
+
for i in range(len(steps)-1):
|
| 210 |
+
x1 = steps[i][0]+1.45
|
| 211 |
+
x2 = steps[i+1][0]+0.05
|
| 212 |
+
y = 6.5
|
| 213 |
+
ax.annotate("", xy=(x2,y), xytext=(x1,y), arrowprops=dict(arrowstyle="->", color="white", lw=2))
|
| 214 |
+
colors_ckd = ["#2ecc71", "#f1c40f", "#e67e22", "#e74c3c", "#c0392b"]
|
| 215 |
+
stages = ["Normal
|
| 216 |
+
<1.2", "Borderline
|
| 217 |
+
1.2-1.5", "Stage 2
|
| 218 |
+
1.5-3.0", "Stage 3-4
|
| 219 |
+
3.0-6.0", "Stage 5
|
| 220 |
+
>6.0"]
|
| 221 |
+
for i, (color, stage) in enumerate(zip(colors_ckd, stages)):
|
| 222 |
+
rect = mpatches.FancyBboxPatch((0.5+i*2.2, 2), 2, 2.5, boxstyle="round,pad=0.1", facecolor=color, edgecolor="white", linewidth=2, alpha=0.8)
|
| 223 |
+
ax.add_patch(rect)
|
| 224 |
+
ax.text(1.5+i*2.2, 3.2, stage, ha="center", va="center", color="white", fontsize=8, fontweight="bold")
|
| 225 |
+
ax.text(6, 1.5, "Creatinine Level (mg/dL)", color="#7eb8f7", fontsize=9, ha="center", fontweight="bold")
|
| 226 |
+
ax.text(6, 4.8, "Jaffe Reaction: Creatinine + Picric Acid β Orange-Red Color", color="#a8b2d8", fontsize=8, ha="center")
|
| 227 |
+
|
| 228 |
+
elif "mhv" in topic_lower or "valve" in topic_lower or "bileaflet" in topic_lower:
|
| 229 |
+
ax.set_title("Mechanical Heart Valve (MHV) β Bileaflet Design", color="white", fontsize=14, fontweight="bold", pad=15)
|
| 230 |
+
circle_outer = plt.Circle((6, 4), 3, color="#2d3a5a", fill=True, zorder=1)
|
| 231 |
+
circle_inner = plt.Circle((6, 4), 2.8, color="#1a2744", fill=True, zorder=2)
|
| 232 |
+
ax.add_patch(circle_outer)
|
| 233 |
+
ax.add_patch(circle_inner)
|
| 234 |
+
border = plt.Circle((6, 4), 3, color="#7eb8f7", fill=False, linewidth=3, zorder=3)
|
| 235 |
+
ax.add_patch(border)
|
| 236 |
+
leaflet1 = mpatches.FancyBboxPatch((4.5, 3), 1.3, 2, boxstyle="round,pad=0.1", facecolor="#e63946", edgecolor="white", linewidth=2, zorder=4)
|
| 237 |
+
leaflet2 = mpatches.FancyBboxPatch((6.2, 3), 1.3, 2, boxstyle="round,pad=0.1", facecolor="#e63946", edgecolor="white", linewidth=2, zorder=4)
|
| 238 |
+
ax.add_patch(leaflet1)
|
| 239 |
+
ax.add_patch(leaflet2)
|
| 240 |
+
ax.text(5.15, 4, "Leaflet
|
| 241 |
+
1", ha="center", va="center", color="white", fontsize=8, fontweight="bold", zorder=5)
|
| 242 |
+
ax.text(6.85, 4, "Leaflet
|
| 243 |
+
2", ha="center", va="center", color="white", fontsize=8, fontweight="bold", zorder=5)
|
| 244 |
+
ax.annotate("", xy=(6, 7.5), xytext=(6, 7), arrowprops=dict(arrowstyle="->", color="#4361ee", lw=3))
|
| 245 |
+
ax.text(6, 7.7, "Blood Flow", color="#4361ee", ha="center", fontsize=9, fontweight="bold")
|
| 246 |
+
ax.annotate("", xy=(6, 0.5), xytext=(6, 1), arrowprops=dict(arrowstyle="->", color="#4361ee", lw=3))
|
| 247 |
+
specs = ["Diameter: 27mm (SJM Regent)", "Material: Pyrolytic Carbon", "Leaflets: 2 (Bileaflet)", "Opening Angle: 85Β°"]
|
| 248 |
+
for i, spec in enumerate(specs):
|
| 249 |
+
ax.text(0.3, 7-i*0.7, "β’ "+spec, color="#a8b2d8", fontsize=8)
|
| 250 |
+
|
| 251 |
+
else:
|
| 252 |
+
ax.set_title("CardioLab AI β Research Overview", color="white", fontsize=14, fontweight="bold", pad=15)
|
| 253 |
+
pillars = [
|
| 254 |
+
(2, 5, "#e63946", "Pillar 1
|
| 255 |
+
MHV Design
|
| 256 |
+
& Testing", ["MCL", "PIV", "FSI"]),
|
| 257 |
+
(5, 5, "#4361ee", "Pillar 2
|
| 258 |
+
Thrombosis
|
| 259 |
+
Research", ["TGT", "Blood Clots", "Hemolysis"]),
|
| 260 |
+
(8, 5, "#2ecc71", "Pillar 3
|
| 261 |
+
CKD
|
| 262 |
+
Diagnostics", ["uPAD", "Jaffe", "Creatinine"]),
|
| 263 |
+
]
|
| 264 |
+
for x, y, color, title, items in pillars:
|
| 265 |
+
rect = mpatches.FancyBboxPatch((x-1, y-0.5), 2.5, 2.5, boxstyle="round,pad=0.2", facecolor=color, edgecolor="white", linewidth=2, alpha=0.9)
|
| 266 |
+
ax.add_patch(rect)
|
| 267 |
+
ax.text(x+0.25, y+1.7, title, ha="center", va="center", color="white", fontsize=9, fontweight="bold")
|
| 268 |
+
for j, item in enumerate(items):
|
| 269 |
+
ax.text(x+0.25, y+1-j*0.5, "β’ "+item, ha="center", color="white", fontsize=8)
|
| 270 |
+
equipment = ["27mm SJM Regent MHV", "Arduino Uno + Stepper Motor", "Time-resolved PIV (Green Laser)", "Sylgard 184 Transparent Sections", "Heska Element HT5 Analyzer"]
|
| 271 |
+
rect_eq = mpatches.FancyBboxPatch((1, 1), 10, 2.5, boxstyle="round,pad=0.2", facecolor="#1a2744", edgecolor="#7eb8f7", linewidth=2)
|
| 272 |
+
ax.add_patch(rect_eq)
|
| 273 |
+
ax.text(6, 3.2, "KEY EQUIPMENT", ha="center", color="#7eb8f7", fontsize=10, fontweight="bold")
|
| 274 |
+
for i, eq in enumerate(equipment):
|
| 275 |
+
col = i % 2
|
| 276 |
+
row = i // 2
|
| 277 |
+
ax.text(2+col*5, 2.7-row*0.7, "β’ "+eq, color="#e2e8f0", fontsize=7.5)
|
| 278 |
+
|
| 279 |
+
buf = io.BytesIO()
|
| 280 |
+
plt.tight_layout()
|
| 281 |
+
plt.savefig(buf, format="png", facecolor=fig.get_facecolor(), bbox_inches="tight", dpi=120)
|
| 282 |
+
buf.seek(0)
|
| 283 |
+
img = Image.open(buf)
|
| 284 |
+
plt.close()
|
| 285 |
+
return img
|
| 286 |
|
| 287 |
def piv_tool(velocity, shear, hr):
|
| 288 |
v = "HIGH - stenosis risk" if float(velocity)>2.0 else "NORMAL"
|
|
|
|
| 297 |
def tgt_tool(tat,pf12,hemo,platelets,time):
|
| 298 |
risk=sum([float(tat)>15,float(pf12)>2.0,float(hemo)>50,float(platelets)<150])
|
| 299 |
r="HIGH THROMBOGENIC RISK" if risk>=3 else "MODERATE RISK" if risk>=2 else "LOW RISK"
|
| 300 |
+
return ("TGT BLOOD ANALYSIS"+chr(10)+"ββββββββββββββββββββ"+chr(10)+
|
|
|
|
| 301 |
"Time: "+str(time)+" min"+chr(10)+
|
| 302 |
"TAT: "+str(tat)+" β "+("HIGH" if float(tat)>15 else "NORMAL")+chr(10)+
|
| 303 |
"PF1.2: "+str(pf12)+" β "+("HIGH" if float(pf12)>2.0 else "NORMAL")+chr(10)+
|
| 304 |
"Hemoglobin: "+str(hemo)+" β "+("HIGH" if float(hemo)>50 else "NORMAL")+chr(10)+
|
| 305 |
"Platelets: "+str(platelets)+" β "+("LOW" if float(platelets)<150 else "NORMAL")+chr(10)+
|
| 306 |
+
"ββββββββββββββββββββ"+chr(10)+"OVERALL: "+r)
|
|
|
|
| 307 |
|
| 308 |
def upad_tool(r,g,b):
|
| 309 |
c=max(0,round(0.02*(float(r)-float(b))-0.5,2))
|
|
|
|
| 312 |
elif c<3.0: s="Stage 2 CKD"
|
| 313 |
elif c<6.0: s="Stage 3-4 CKD"
|
| 314 |
else: s="Stage 5 CKD - Kidney Failure"
|
| 315 |
+
return ("uPAD CKD ANALYSIS"+chr(10)+"ββββββββββββββββββββ"+chr(10)+
|
| 316 |
+
"RGB: R="+str(r)+" G="+str(g)+" B="+str(b)+chr(10)+
|
| 317 |
+
"Creatinine: "+str(c)+" mg/dL"+chr(10)+
|
| 318 |
+
"ββββββββββββββββββββ"+chr(10)+"CKD STAGE: "+s+chr(10)+
|
|
|
|
|
|
|
|
|
|
| 319 |
"Confirm with: Heska Element HT5")
|
| 320 |
|
| 321 |
with gr.Blocks(title="CardioLab AI", css=CSS) as demo:
|
|
|
|
| 322 |
gr.HTML("""
|
| 323 |
<div class="main-header">
|
| 324 |
+
<div style="font-size:2.8em;font-weight:900;color:#ffffff;letter-spacing:3px;text-shadow:0 0 30px rgba(255,255,255,0.3);">
|
| 325 |
β€οΈ CardioLab AI
|
| 326 |
</div>
|
| 327 |
</div>
|
|
|
|
| 331 |
with gr.Tab("π¬ Chat"):
|
| 332 |
chatbot = gr.Chatbot(label="", height=450)
|
| 333 |
with gr.Row():
|
| 334 |
+
msg_box = gr.Textbox(placeholder="Ask anything about CardioLab research...", label="", lines=2, scale=4)
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 335 |
with gr.Column(scale=1, min_width=100):
|
| 336 |
send_btn = gr.Button("Send β€", variant="primary")
|
| 337 |
clear_btn = gr.Button("Clear", variant="secondary")
|
|
|
|
| 352 |
with gr.Tab("π Papers"):
|
| 353 |
gr.Markdown("### Search latest research papers with verified working links")
|
| 354 |
with gr.Row():
|
| 355 |
+
search_input = gr.Textbox(placeholder="e.g. mechanical heart valve thrombogenicity", label="Research Topic", scale=4)
|
|
|
|
|
|
|
|
|
|
|
|
|
| 356 |
search_btn = gr.Button("Search β€", variant="primary", scale=1)
|
| 357 |
search_output = gr.Textbox(label="Results β Verified Links Only", lines=18)
|
| 358 |
search_btn.click(quick_search, inputs=search_input, outputs=search_output)
|
| 359 |
search_input.submit(quick_search, inputs=search_input, outputs=search_output)
|
| 360 |
+
gr.Markdown("**Try:** `TGT thrombogenicity` | `creatinine uPAD` | `bileaflet MHV PIV` | `CKD point-of-care`")
|
| 361 |
|
| 362 |
with gr.Tab("π¨ Diagrams"):
|
| 363 |
+
gr.Markdown("### Generate real visual diagrams of CardioLab equipment and systems")
|
| 364 |
with gr.Row():
|
| 365 |
+
diagram_input = gr.Textbox(placeholder="e.g. TGT setup | MCL PIV system | uPAD CKD | MHV bileaflet valve | CardioLab overview", label="What to diagram", scale=4)
|
|
|
|
|
|
|
|
|
|
|
|
|
| 366 |
diagram_btn = gr.Button("Generate β€", variant="primary", scale=1)
|
| 367 |
+
diagram_output = gr.Image(label="Visual Diagram", type="pil")
|
| 368 |
diagram_btn.click(generate_diagram, inputs=diagram_input, outputs=diagram_output)
|
| 369 |
+
gr.Markdown("**Try these:** `TGT setup` | `MCL PIV system` | `uPAD CKD flow` | `MHV bileaflet valve` | `CardioLab overview`")
|
| 370 |
|
| 371 |
with gr.Tab("π PIV"):
|
| 372 |
gr.Markdown("### Analyze Particle Image Velocimetry data from Mock Circulatory Loop")
|
| 373 |
with gr.Row():
|
| 374 |
with gr.Column():
|
| 375 |
+
v=gr.Number(label="Max Velocity (m/s)", value=1.8, info="Normal: 0.5-2.0 m/s")
|
| 376 |
s=gr.Number(label="Wall Shear Stress (Pa)", value=6.5, info="Normal: below 5 Pa")
|
| 377 |
+
h=gr.Number(label="Heart Rate (bpm)", value=72, info="Normal: 60-100 bpm")
|
| 378 |
+
piv_btn = gr.Button("Analyze PIV β€", variant="primary")
|
| 379 |
with gr.Column():
|
| 380 |
piv_out=gr.Textbox(label="Analysis Result", lines=8)
|
| 381 |
piv_btn.click(piv_tool, inputs=[v,s,h], outputs=piv_out)
|
|
|
|
| 387 |
t1=gr.Number(label="TAT (ng/mL)", value=18, info="Normal: below 8")
|
| 388 |
t2=gr.Number(label="PF1.2 (nmol/L)", value=2.5, info="Normal: below 2.0")
|
| 389 |
t3=gr.Number(label="Free Hemoglobin (mg/L)", value=60, info="Normal: below 20")
|
| 390 |
+
t4=gr.Number(label="Platelet Count", value=140, info="Normal: above 150")
|
| 391 |
t5=gr.Number(label="Time (minutes)", value=40)
|
| 392 |
+
tgt_btn = gr.Button("Analyze TGT β€", variant="primary")
|
| 393 |
with gr.Column():
|
| 394 |
out2=gr.Textbox(label="Analysis Result", lines=12)
|
| 395 |
tgt_btn.click(tgt_tool, inputs=[t1,t2,t3,t4,t5], outputs=out2)
|
|
|
|
| 398 |
gr.Markdown("### Analyze uPAD colorimetric result using Jaffe Reaction for CKD diagnosis")
|
| 399 |
with gr.Row():
|
| 400 |
with gr.Column():
|
| 401 |
+
r=gr.Number(label="R (Red)", value=210, info="Range: 0-255")
|
| 402 |
+
g=gr.Number(label="G (Green)", value=140, info="Range: 0-255")
|
| 403 |
+
b=gr.Number(label="B (Blue)", value=80, info="Range: 0-255")
|
|
|
|
| 404 |
upad_btn = gr.Button("Analyze uPAD β€", variant="primary")
|
| 405 |
with gr.Column():
|
| 406 |
out3=gr.Textbox(label="CKD Analysis Result", lines=10)
|