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  timestamp_utc,session_id,first_name,last_name,question,answer,rating,comment
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- 2025-09-15T01:16:49.957987+00:00,d8948ef5-9235-4f5a-b6d3-a3cbe4661f5e,Pankti,Parikh,The femur bone is attached with which other bones in human being ?,"[Answer]: In humans, the femur is connected to the pelVIS by the hip joint, specifically the acetabulum of the iliac bone, and to the tibia and patella via the knee joint. The femur also has a connection to the patella through the quadriceps tendon and the patellar ligament.",5,I got the exact answer regarding human anatomy by this site
 
 
 
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+ 2025-09-15T01:57:03.517513+00:00,50f50ee0-0bcb-4c1a-b1f8-3f9ed70da18c,Shubh,Laiwala,Mechanism of thyroxine hornone,"[LLM fallback ungrounded]
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+ Thyroid hormones play a crucial role in the development and maintenance of musculosketal systems, including bone metabolism. Thyroxin (T4) and triiodothyronine (T3) bind to thyroid hormone receptors (TRs) in osteoblasts, stimulating the expression of genes involved in bone formation and resorption, thereby promoting bone growth and remodeling. The thyroid gland secretes T4 and T3, which are transported to target tissues by thyroid-binding globulin (TBG), thyroid binding prealbumin (transthyretin), and albumin. In bone, thyroid receptores are expressed in ossification cells, chondrocytes, and osteoclasts. Thryoid hormones increase osteogenic differentiation of mesenchymal stem cells, enhance osteoprogenitor cell proliferation, and promote osteocalcin expression. They also inhibit osteo-clastogenesis and increase bone turnover. In addition, thyroids regulate the expression and activity of other growth factors, such as IGF-1 and BMPs, and",2,