File size: 31,671 Bytes
75ebbe5
ef69ec1
 
75ebbe5
c421c59
75ebbe5
b45d525
75ebbe5
1ba8e97
75ebbe5
ef69ec1
 
 
ff7f2b3
bf0aa04
1ba8e97
 
ff7f2b3
75ebbe5
bf0aa04
 
75ebbe5
bf0aa04
75ebbe5
16d2812
bfd9991
16d2812
1ba8e97
 
 
bf0aa04
75ebbe5
 
bf0aa04
1ba8e97
75ebbe5
bf0aa04
75ebbe5
bf0aa04
75ebbe5
862d7cb
ef69ec1
bf0aa04
75ebbe5
bf0aa04
75ebbe5
bf0aa04
75ebbe5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ef69ec1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
bfd9991
ef69ec1
bfd9991
ef69ec1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
bfd9991
c9c6cf5
75ebbe5
 
 
 
 
 
ef69ec1
75ebbe5
ef69ec1
75ebbe5
 
 
 
 
 
 
 
 
 
bfd9991
bf0aa04
 
75ebbe5
 
bf0aa04
75ebbe5
bf0aa04
75ebbe5
 
 
bfd9991
75ebbe5
 
 
bf0aa04
 
75ebbe5
bfd9991
bf0aa04
 
862d7cb
bf0aa04
 
75ebbe5
 
 
 
 
bfd9991
bf0aa04
75ebbe5
bfd9991
862d7cb
bf0aa04
 
75ebbe5
bfd9991
bf0aa04
75ebbe5
bfd9991
862d7cb
bf0aa04
 
 
bfd9991
bf0aa04
75ebbe5
bfd9991
bf0aa04
75ebbe5
bf0aa04
 
bfd9991
75ebbe5
 
 
 
 
bfd9991
75ebbe5
 
bfd9991
75ebbe5
 
 
 
 
 
 
bfd9991
75ebbe5
bfd9991
75ebbe5
 
bfd9991
bf0aa04
 
bfd9991
bf0aa04
 
 
 
ef69ec1
1ba8e97
 
68e317b
1ba8e97
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
68e317b
 
 
 
1ba8e97
 
 
 
68e317b
1ba8e97
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
abbf692
1ba8e97
 
ef69ec1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1ba8e97
 
 
abbf692
1ba8e97
abbf692
 
1ba8e97
 
 
 
abbf692
1ba8e97
 
 
abbf692
1ba8e97
 
 
 
 
 
 
 
 
 
 
 
68e317b
abbf692
1ba8e97
68e317b
 
1ba8e97
68e317b
1ba8e97
ef69ec1
abbf692
 
ef69ec1
 
 
abbf692
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1ba8e97
 
ef69ec1
b45d525
 
bf0aa04
 
 
 
 
2f39e2e
75ebbe5
 
 
 
 
ef69ec1
1ba8e97
ef69ec1
 
1ba8e97
862d7cb
abbf692
1ba8e97
75ebbe5
ef69ec1
1ba8e97
75ebbe5
ef69ec1
1ba8e97
 
 
68e317b
1ba8e97
75ebbe5
ef69ec1
abbf692
75ebbe5
7e7d8ff
75ebbe5
 
 
1ba8e97
 
ef69ec1
abbf692
75ebbe5
ef69ec1
75ebbe5
abbf692
1ba8e97
ef69ec1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
abbf692
ef69ec1
1ba8e97
ef69ec1
 
abbf692
 
 
1ba8e97
ef69ec1
 
abbf692
 
 
1ba8e97
 
ef69ec1
1ba8e97
 
 
 
 
75ebbe5
1ba8e97
 
 
 
 
 
 
abbf692
ef69ec1
1ba8e97
 
 
abbf692
 
 
 
 
 
 
1ba8e97
 
 
 
 
 
 
 
 
ef69ec1
75ebbe5
 
 
 
1ba8e97
75ebbe5
 
 
bfd9991
75ebbe5
 
 
1ba8e97
 
 
 
abbf692
75ebbe5
1ba8e97
 
 
 
75ebbe5
862d7cb
 
1ba8e97
75ebbe5
b45d525
ef69ec1
a923317
862d7cb
75ebbe5
 
7e7d8ff
75ebbe5
 
1ba8e97
75ebbe5
 
1ba8e97
75ebbe5
 
 
 
 
 
862d7cb
75ebbe5
862d7cb
 
75ebbe5
 
862d7cb
7e7d8ff
862d7cb
 
7e7d8ff
862d7cb
75ebbe5
862d7cb
981c773
1ba8e97
862d7cb
75ebbe5
 
 
1ba8e97
 
75ebbe5
 
 
 
 
 
 
 
 
 
bfd9991
75ebbe5
 
 
bfd9991
75ebbe5
 
862d7cb
b45d525
75ebbe5
 
 
 
 
 
 
 
 
c9c6cf5
75ebbe5
 
 
 
 
 
 
 
 
 
a923317
862d7cb
 
75ebbe5
 
862d7cb
 
 
75ebbe5
bfd9991
862d7cb
75ebbe5
bfd9991
862d7cb
 
 
 
bfd9991
862d7cb
bfd9991
75ebbe5
862d7cb
 
 
 
75ebbe5
862d7cb
 
75ebbe5
862d7cb
b45d525
75ebbe5
b45d525
862d7cb
 
75ebbe5
 
 
bfd9991
 
 
 
 
 
 
 
75ebbe5
 
 
 
 
 
 
862d7cb
75ebbe5
bfd9991
75ebbe5
862d7cb
75ebbe5
 
 
 
bfd9991
 
 
862d7cb
b45d525
e35f4e1
862d7cb
75ebbe5
 
 
 
 
 
862d7cb
 
75ebbe5
862d7cb
 
75ebbe5
862d7cb
75ebbe5
862d7cb
 
 
 
 
 
75ebbe5
 
862d7cb
 
 
75ebbe5
 
 
 
 
 
1ba8e97
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
# smartheal_ai_processor.py
# Fully functional: robust segmentation + safe overlays + conditional GPU wrapper.
# All original class/function names preserved. New helpers are additive.

import os
import time
import logging
from datetime import datetime
from typing import Optional, Dict, List, Tuple

# --- quiet tokenizers fork warning (HF) ---
os.environ.setdefault("TOKENIZERS_PARALLELISM", "false")

import cv2
import numpy as np
from PIL import Image, ImageOps
from PIL.ExifTags import TAGS

logging.basicConfig(level=logging.INFO, format="%(asctime)s - %(levelname)s - %(message)s")

UPLOADS_DIR = "uploads"
os.makedirs(UPLOADS_DIR, exist_ok=True)

HF_TOKEN = os.getenv("HF_TOKEN", None)
YOLO_MODEL_PATH = "src/best.pt"
SEG_MODEL_PATH = "src/segmentation_model.h5"   # optional
GUIDELINE_PDFS = ["src/eHealth in Wound Care.pdf", "src/IWGDF Guideline.pdf", "src/evaluation.pdf"]
DATASET_ID = "SmartHeal/wound-image-uploads"
DEFAULT_PX_PER_CM = 38.0  # fallback when we cannot calibrate
PX_PER_CM_MIN, PX_PER_CM_MAX = 5.0, 1200.0  # sanity bounds

models_cache: Dict[str, object] = {}
knowledge_base_cache: Dict[str, object] = {}

# ---------- Lazy imports ----------
def _import_ultralytics():
    from ultralytics import YOLO
    return YOLO

def _import_tf_loader():
    import tensorflow as tf
    tf.config.set_visible_devices([], "GPU")  # force CPU for TF to avoid CUDA contention
    from tensorflow.keras.models import load_model
    return load_model

def _import_hf_cls():
    from transformers import pipeline
    return pipeline

def _import_embeddings():
    from langchain_community.embeddings import HuggingFaceEmbeddings
    return HuggingFaceEmbeddings

def _import_langchain_pdf():
    from langchain_community.document_loaders import PyPDFLoader
    return PyPDFLoader

def _import_langchain_faiss():
    from langchain_community.vectorstores import FAISS
    return FAISS

def _import_hf_hub():
    from huggingface_hub import HfApi, HfFolder
    return HfApi, HfFolder

# ---------- Conditional Spaces GPU function ----------
# Avoid scheduling a GPU worker when CUDA is not available (prevents cudaGetDeviceCount crash)
def _cuda_available() -> bool:
    try:
        import torch
        return bool(getattr(torch, "cuda", None)) and torch.cuda.is_available()
    except Exception:
        return False

def _generate_medgemma_report_core(
    patient_info: str,
    visual_results: Dict,
    guideline_context: str,
    image_pil: Image.Image,
    max_new_tokens: Optional[int] = None,
) -> str:
    try:
        from transformers import pipeline
        # Use CPU by default; if CUDA truly available, pipeline can still map automatically
        pipe = pipeline(
            "image-text-to-text",
            model="google/medgemma-4b-it",
            device_map="auto" if _cuda_available() else None,
            token=HF_TOKEN,
            model_kwargs={"low_cpu_mem_usage": True, "use_cache": True},
        )

        prompt = (
            "You are a medical AI assistant. Analyze this wound image and patient data.\n\n"
            f"Patient: {patient_info}\n"
            f"Wound: {visual_results.get('wound_type', 'Unknown')} - "
            f"{visual_results.get('length_cm', 0)}Γ—{visual_results.get('breadth_cm', 0)} cm\n\n"
            "Provide a structured report with:\n"
            "1. Clinical Summary\n2. Treatment Recommendations\n3. Risk Assessment\n4. Monitoring Plan\n"
        )

        messages = [{"role": "user", "content": [
            {"type": "image", "image": image_pil},
            {"type": "text",  "text": prompt},
        ]}]

        t0 = time.time()
        out = pipe(
            text=messages,
            max_new_tokens=max_new_tokens or 800,
            do_sample=False,
            temperature=0.7,
        )
        logging.info(f"βœ… MedGemma finished in {time.time()-t0:.2f}s")

        if out and len(out) > 0:
            try:
                return out[0]["generated_text"][-1].get("content", "").strip() or "⚠️ Empty response"
            except Exception:
                return (out[0].get("generated_text", "") or "").strip() or "⚠️ Empty response"
        return "⚠️ No output generated"
    except Exception as e:
        logging.error(f"❌ MedGemma generation error: {e}")
        return "⚠️ GPU/LLM worker unavailable"

# Preserve the SAME public function name.
# Only decorate with @spaces.GPU if CUDA is truly available.
try:
    import spaces
    if _cuda_available():
        @spaces.GPU(enable_queue=True, duration=90)
        def generate_medgemma_report(
            patient_info: str,
            visual_results: Dict,
            guideline_context: str,
            image_pil: Image.Image,
            max_new_tokens: Optional[int] = None,
        ) -> str:
            return _generate_medgemma_report_core(patient_info, visual_results, guideline_context, image_pil, max_new_tokens)
    else:
        def generate_medgemma_report(
            patient_info: str,
            visual_results: Dict,
            guideline_context: str,
            image_pil: Image.Image,
            max_new_tokens: Optional[int] = None,
        ) -> str:
            # no decorator -> no GPU worker init -> no cudaGetDeviceCount crash
            return _generate_medgemma_report_core(patient_info, visual_results, guideline_context, image_pil, max_new_tokens)
except Exception:
    def generate_medgemma_report(
        patient_info: str,
        visual_results: Dict,
        guideline_context: str,
        image_pil: Image.Image,
        max_new_tokens: Optional[int] = None,
    ) -> str:
        return _generate_medgemma_report_core(patient_info, visual_results, guideline_context, image_pil, max_new_tokens)

# ---------- Initialize CPU models ----------
def load_yolo_model():
    YOLO = _import_ultralytics()
    return YOLO(YOLO_MODEL_PATH)

def load_segmentation_model():
    load_model = _import_tf_loader()
    return load_model(SEG_MODEL_PATH, compile=False)

def load_classification_pipeline():
    pipe = _import_hf_cls()
    return pipe("image-classification", model="Hemg/Wound-classification", token=HF_TOKEN, device="cpu")

def load_embedding_model():
    Emb = _import_embeddings()
    return Emb(model_name="sentence-transformers/all-MiniLM-L6-v2", model_kwargs={"device": "cpu"})

def initialize_cpu_models() -> None:
    if HF_TOKEN:
        try:
            HfApi, HfFolder = _import_hf_hub()
            HfFolder.save_token(HF_TOKEN)
            logging.info("βœ… HF token set")
        except Exception as e:
            logging.warning(f"HF token save failed: {e}")

    if "det" not in models_cache:
        try:
            models_cache["det"] = load_yolo_model()
            logging.info("βœ… YOLO loaded (CPU)")
        except Exception as e:
            logging.error(f"YOLO load failed: {e}")

    if "seg" not in models_cache:
        try:
            if os.path.exists(SEG_MODEL_PATH):
                models_cache["seg"] = load_segmentation_model()
                logging.info("βœ… Segmentation model loaded (CPU)")
            else:
                models_cache["seg"] = None
                logging.warning("Segmentation model file missing; skipping.")
        except Exception as e:
            models_cache["seg"] = None
            logging.warning(f"Segmentation unavailable: {e}")

    if "cls" not in models_cache:
        try:
            models_cache["cls"] = load_classification_pipeline()
            logging.info("βœ… Classifier loaded (CPU)")
        except Exception as e:
            models_cache["cls"] = None
            logging.warning(f"Classifier unavailable: {e}")

    if "embedding_model" not in models_cache:
        try:
            models_cache["embedding_model"] = load_embedding_model()
            logging.info("βœ… Embeddings loaded (CPU)")
        except Exception as e:
            models_cache["embedding_model"] = None
            logging.warning(f"Embeddings unavailable: {e}")

def setup_knowledge_base() -> None:
    if "vector_store" in knowledge_base_cache:
        return
    docs: List = []
    try:
        PyPDFLoader = _import_langchain_pdf()
        for pdf in GUIDELINE_PDFS:
            if os.path.exists(pdf):
                try:
                    docs.extend(PyPDFLoader(pdf).load())
                    logging.info(f"Loaded PDF: {pdf}")
                except Exception as e:
                    logging.warning(f"PDF load failed ({pdf}): {e}")
    except Exception as e:
        logging.warning(f"LangChain PDF loader unavailable: {e}")

    if docs and models_cache.get("embedding_model"):
        try:
            from langchain.text_splitter import RecursiveCharacterTextSplitter
            FAISS = _import_langchain_faiss()
            chunks = RecursiveCharacterTextSplitter(chunk_size=1000, chunk_overlap=100).split_documents(docs)
            knowledge_base_cache["vector_store"] = FAISS.from_documents(chunks, models_cache["embedding_model"])
            logging.info(f"βœ… Knowledge base ready ({len(chunks)} chunks)")
        except Exception as e:
            knowledge_base_cache["vector_store"] = None
            logging.warning(f"KB build failed: {e}")
    else:
        knowledge_base_cache["vector_store"] = None
        logging.warning("KB disabled (no docs or embeddings).")

initialize_cpu_models()
setup_knowledge_base()

# ---------- Calibration helpers ----------
def _exif_to_dict(pil_img: Image.Image) -> Dict[str, object]:
    out = {}
    try:
        exif = pil_img.getexif()
        if not exif:
            return out
        for k, v in exif.items():
            tag = TAGS.get(k, k)
            out[tag] = v
    except Exception:
        pass
    return out

def _to_float(val) -> Optional[float]:
    try:
        if val is None:
            return None
        if isinstance(val, tuple) and len(val) == 2:
            num, den = float(val[0]), float(val[1]) if float(val[1]) != 0 else 1.0
            return num / den
        return float(val)
    except Exception:
        return None

def _estimate_sensor_width_mm(f_mm: Optional[float], f35: Optional[float]) -> Optional[float]:
    if f_mm and f35 and f35 > 0:
        return 36.0 * f_mm / f35
    return None

def estimate_px_per_cm_from_exif(pil_img: Image.Image, default_px_per_cm: float = DEFAULT_PX_PER_CM) -> Tuple[float, Dict]:
    meta = {"used": "default", "f_mm": None, "f35": None, "sensor_w_mm": None, "distance_m": None}
    try:
        exif = _exif_to_dict(pil_img)
        f_mm = _to_float(exif.get("FocalLength"))
        f35 = _to_float(exif.get("FocalLengthIn35mmFilm") or exif.get("FocalLengthIn35mm"))
        subj_dist_m = _to_float(exif.get("SubjectDistance"))
        sensor_w_mm = _estimate_sensor_width_mm(f_mm, f35)

        meta.update({"f_mm": f_mm, "f35": f35, "sensor_w_mm": sensor_w_mm, "distance_m": subj_dist_m})

        if f_mm and sensor_w_mm and subj_dist_m and subj_dist_m > 0:
            w_px = pil_img.width
            field_w_mm = sensor_w_mm * (subj_dist_m * 1000.0) / f_mm
            field_w_cm = field_w_mm / 10.0
            px_per_cm = w_px / max(field_w_cm, 1e-6)
            px_per_cm = float(np.clip(px_per_cm, PX_PER_CM_MIN, PX_PER_CM_MAX))
            meta["used"] = "exif"
            return px_per_cm, meta
        return float(default_px_per_cm), meta
    except Exception:
        return float(default_px_per_cm), meta

# ---------- Segmentation helpers (additive; names preserved elsewhere) ----------
def _get_seg_hw(seg_model) -> Tuple[int, int]:
    shp = getattr(seg_model, "input_shape", None)
    if shp and len(shp) >= 4:
        return int(shp[1]), int(shp[2])
    # try Keras .inputs shape
    try:
        shp = seg_model.inputs[0].shape
        return int(shp[1]), int(shp[2])
    except Exception:
        pass
    raise ValueError(f"Cannot infer (H,W) from segmentation model input shape: {shp}")

def _to_prob(mask_pred: np.ndarray) -> np.ndarray:
    m = np.array(mask_pred)
    # squeeze batch/channel dims
    while m.ndim > 2:
        if m.shape[0] == 1:
            m = np.squeeze(m, axis=0)
        if m.ndim > 2 and m.shape[-1] == 1:
            m = np.squeeze(m, axis=-1)
        if m.ndim == 3 and m.shape[-1] > 1:
            # pick the most active channel
            ch = np.argmax(m.reshape(-1, m.shape[-1]).mean(0))
            m = m[..., ch]
        if m.ndim <= 2:
            break
    m = m.astype("float32")
    # if looks like logits -> sigmoid
    if m.max() > 1.5 or m.min() < -0.5:
        m = 1.0 / (1.0 + np.exp(-m))
    return np.clip(m, 0.0, 1.0)

def _adaptive_threshold(prob: np.ndarray, hard: float = 0.5) -> np.ndarray:
    if (prob >= hard).sum() > 0:
        return (prob >= hard).astype("uint8")
    # try Otsu
    m8 = (np.clip(prob, 0, 1) * 255).astype("uint8")
    try:
        # we only need the threshold value _
        _, _ = cv2.threshold(m8, 0, 255, cv2.THRESH_BINARY + cv2.THRESH_OTSU)
        return (m8 >= _).astype("uint8")
    except Exception:
        p = float(np.percentile(prob, 99.0))
        return (prob >= max(0.2, min(0.9, p))).astype("uint8")

def largest_component_mask(binary: np.ndarray, min_area_px: int = 50) -> np.ndarray:
    num, labels, stats, _ = cv2.connectedComponentsWithStats(binary.astype(np.uint8), connectivity=8)
    if num <= 1:
        return binary.astype(np.uint8)
    areas = stats[1:, cv2.CC_STAT_AREA]
    if areas.size == 0 or areas.max() < min_area_px:
        return binary.astype(np.uint8)
    largest_idx = 1 + int(np.argmax(areas))
    return (labels == largest_idx).astype(np.uint8)

def measure_min_area_rect(mask: np.ndarray, px_per_cm: float) -> Tuple[float, float, Tuple]:
    contours, _ = cv2.findContours(mask.astype(np.uint8), cv2.RETR_EXTERNAL, cv2.CHAIN_APPROX_SIMPLE)
    if not contours:
        return 0.0, 0.0, (None, None)
    cnt = max(contours, key=cv2.contourArea)
    rect = cv2.minAreaRect(cnt)
    (w_px, h_px) = rect[1]
    length_px, breadth_px = (max(w_px, h_px), min(w_px, h_px))
    length_cm = round(length_px / max(px_per_cm, 1e-6), 2)
    breadth_cm = round(breadth_px / max(px_per_cm, 1e-6), 2)
    box = cv2.boxPoints(rect).astype(int)
    return length_cm, breadth_cm, (box, rect[0])

def count_area_cm2(mask: np.ndarray, px_per_cm: float) -> float:
    px_count = float(mask.astype(bool).sum())
    return round(px_count / (max(px_per_cm, 1e-6) ** 2), 2)

def draw_measurement_overlay(
    base_bgr: np.ndarray,
    mask01: np.ndarray,
    rect_box: np.ndarray,
    length_cm: float,
    breadth_cm: float,
    thickness: int = 2
) -> np.ndarray:
    overlay = base_bgr.copy()
    # safe blend: blend once, then gate with mask (no mask kwarg!)
    colored = np.zeros_like(base_bgr); colored[:] = (0, 0, 255)
    blended = cv2.addWeighted(overlay, 1.0, colored, 0.3, 0)
    m3 = np.dstack([mask01 * 255] * 3).astype("uint8")
    blended_masked = cv2.bitwise_and(blended, m3)
    bg = cv2.bitwise_and(overlay, cv2.bitwise_not(m3))
    overlay = cv2.add(bg, blended_masked)

    if rect_box is not None:
        cv2.polylines(overlay, [rect_box], True, (255, 255, 255), thickness)

        pts = rect_box.reshape(-1, 2)
        def midpoint(a, b): return ((a[0] + b[0]) // 2, (a[1] + b[1]) // 2)
        mids = [midpoint(pts[i], pts[(i+1) % 4]) for i in range(4)]
        e_lens = [np.linalg.norm(pts[i] - pts[(i+1) % 4]) for i in range(4)]
        long_pair = (0, 2) if e_lens[0] + e_lens[2] >= e_lens[1] + e_lens[3] else (1, 3)
        short_pair = (1, 3) if long_pair == (0, 2) else (0, 2)

        def draw_arrow(img, p1, p2):
            cv2.arrowedLine(img, p1, p2, (0, 0, 0), thickness + 2, tipLength=0.05)
            cv2.arrowedLine(img, p2, p1, (0, 0, 0), thickness + 2, tipLength=0.05)
            cv2.arrowedLine(img, p1, p2, (255, 255, 255), thickness, tipLength=0.05)
            cv2.arrowedLine(img, p2, p1, (255, 255, 255), thickness, tipLength=0.05)

        draw_arrow(overlay, mids[long_pair[0]], mids[long_pair[1]])
        draw_arrow(overlay, mids[short_pair[0]], mids[short_pair[1]])

        def put_label(text, org):
            cv2.putText(overlay, text, (org[0] + 4, org[1] - 4),
                        cv2.FONT_HERSHEY_SIMPLEX, 0.7, (0, 0, 0), 4, cv2.LINE_AA)
            cv2.putText(overlay, text, (org[0] + 4, org[1] - 4),
                        cv2.FONT_HERSHEY_SIMPLEX, 0.7, (255, 255, 255), 2, cv2.LINE_AA)

        put_label(f"{length_cm:.2f} cm", mids[long_pair[0]])
        put_label(f"{breadth_cm:.2f} cm", mids[short_pair[0]])
    return overlay

# ---------- AI PROCESSOR ----------
class AIProcessor:
    def __init__(self):
        self.models_cache = models_cache
        self.knowledge_base_cache = knowledge_base_cache
        self.uploads_dir = UPLOADS_DIR
        self.dataset_id = DATASET_ID
        self.hf_token = HF_TOKEN

    def _ensure_analysis_dir(self) -> str:
        out_dir = os.path.join(self.uploads_dir, "analysis")
        os.makedirs(out_dir, exist_ok=True)
        return out_dir

    def perform_visual_analysis(self, image_pil: Image.Image) -> Dict:
        """
        Detect β†’ crop ROI β†’ (optional) segment β†’ cleanup β†’ largest component β†’
        oriented minAreaRect in cm (EXIF-calibrated) β†’ save original/detect/seg/annotated.
        """
        try:
            # --- Auto calibration from EXIF ---
            px_per_cm, exif_meta = estimate_px_per_cm_from_exif(image_pil, DEFAULT_PX_PER_CM)

            # Convert PIL to OpenCV BGR
            image_cv = cv2.cvtColor(np.array(image_pil.convert("RGB")), cv2.COLOR_RGB2BGR)

            # --- Detection (YOLO) ---
            det_model = self.models_cache.get("det")
            if det_model is None:
                raise RuntimeError("YOLO model not loaded")

            results = det_model.predict(image_cv, verbose=False, device="cpu")
            if not results or not getattr(results[0], "boxes", None) or len(results[0].boxes) == 0:
                import gradio as gr  # local import to keep class name intact if gradio missing
                raise gr.Error("No wound could be detected.")

            box = results[0].boxes[0].xyxy[0].cpu().numpy().astype(int)
            x1, y1, x2, y2 = [int(v) for v in box]
            x1, y1 = max(0, x1), max(0, y1)
            x2, y2 = min(image_cv.shape[1], x2), min(image_cv.shape[0], y2)
            roi = image_cv[y1:y2, x1:x2].copy()
            if roi.size == 0:
                import gradio as gr
                raise gr.Error("Detected ROI is empty.")

            # --- Segmentation (robust) ---
            seg_model = self.models_cache.get("seg")
            mask_roi_01 = None
            if seg_model is not None:
                try:
                    H, W = _get_seg_hw(seg_model)      # robust (H,W)
                    resized = cv2.resize(roi, (W, H))  # cv2.resize expects (W,H)
                    pred = seg_model.predict(np.expand_dims(resized / 255.0, 0), verbose=0)
                    prob = _to_prob(pred)              # (H,W) in [0,1]
                    binmask = _adaptive_threshold(prob, hard=0.5)
                    # gentle cleanup + largest component
                    binmask = cv2.morphologyEx(binmask, cv2.MORPH_OPEN, np.ones((3,3), np.uint8), iterations=1)
                    binmask = cv2.morphologyEx(binmask, cv2.MORPH_CLOSE, np.ones((3,3), np.uint8), iterations=1)
                    binmask = largest_component_mask(binmask, min_area_px=30)
                    # back to ROI size {0,1}
                    mask_roi_01 = cv2.resize(binmask, (roi.shape[1], roi.shape[0]), interpolation=cv2.INTER_NEAREST).astype(np.uint8)
                    logging.info(f"seg prob stats: min={prob.min():.4f}, max={prob.max():.4f}, mean={prob.mean():.4f}; on={(mask_roi_01==1).sum()}")
                except Exception as e:
                    logging.warning(f"Segmentation failed: {e}")
                    mask_roi_01 = None
            else:
                logging.info("Skipping segmentation (no model).")

            # --- Measurement ---
            if mask_roi_01 is not None and mask_roi_01.any():
                length_cm, breadth_cm, (box_pts, _) = measure_min_area_rect(mask_roi_01, px_per_cm)
                surface_area_cm2 = count_area_cm2(mask_roi_01, px_per_cm)
                anno_roi = draw_measurement_overlay(roi, mask_roi_01, box_pts, length_cm, breadth_cm)
            else:
                # fallback to detection-box cm
                h_px = max(0, y2 - y1); w_px = max(0, x2 - x1)
                length_cm = round(h_px / px_per_cm, 2)
                breadth_cm = round(w_px / px_per_cm, 2)
                surface_area_cm2 = round((h_px * w_px) / (px_per_cm ** 2), 2)
                anno_roi = roi.copy()

            # --- Save visualizations ---
            out_dir = self._ensure_analysis_dir()
            ts = datetime.now().strftime("%Y%m%d_%H%M%S")

            original_path = os.path.join(out_dir, f"original_{ts}.png")
            cv2.imwrite(original_path, image_cv)

            det_vis = image_cv.copy()
            cv2.rectangle(det_vis, (x1, y1), (x2, y2), (0, 255, 0), 2)
            detection_path = os.path.join(out_dir, f"detection_{ts}.png")
            cv2.imwrite(detection_path, det_vis)

            segmentation_path = None
            annotated_seg_path = None
            if mask_roi_01 is not None and mask_roi_01.any():
                # safe masked blend (no mask kwarg to addWeighted)
                seg_full = image_cv.copy()
                roi_overlay = roi.copy()
                red = np.zeros_like(roi_overlay); red[:] = (0, 0, 255)
                blended = cv2.addWeighted(roi_overlay, 1.0, red, 0.3, 0)
                mask_u8 = (mask_roi_01.astype(np.uint8) * 255)
                mask3 = cv2.merge([mask_u8, mask_u8, mask_u8])
                blended_masked = cv2.bitwise_and(blended, mask3)
                roi_bg = cv2.bitwise_and(roi_overlay, cv2.bitwise_not(mask3))
                roi_overlay = cv2.add(roi_bg, blended_masked)

                seg_full[y1:y2, x1:x2] = roi_overlay
                segmentation_path = os.path.join(out_dir, f"segmentation_{ts}.png")
                cv2.imwrite(segmentation_path, seg_full)

                anno_full = image_cv.copy()
                anno_full[y1:y2, x1:x2] = anno_roi
                annotated_seg_path = os.path.join(out_dir, f"segmentation_annotated_{ts}.png")
                cv2.imwrite(annotated_seg_path, anno_full)

            # --- Optional classification ---
            wound_type = "Unknown"
            cls_pipe = self.models_cache.get("cls")
            if cls_pipe is not None:
                try:
                    preds = cls_pipe(Image.fromarray(cv2.cvtColor(roi, cv2.COLOR_BGR2RGB)))
                    if preds:
                        wound_type = max(preds, key=lambda x: x.get("score", 0)).get("label", "Unknown")
                except Exception as e:
                    logging.warning(f"Classification failed: {e}")

            return {
                "wound_type": wound_type,
                "length_cm": length_cm,
                "breadth_cm": breadth_cm,
                "surface_area_cm2": surface_area_cm2,
                "px_per_cm": round(px_per_cm, 2),
                "calibration_meta": exif_meta,
                "detection_confidence": float(results[0].boxes.conf[0].cpu().item())
                    if getattr(results[0].boxes, "conf", None) is not None else 0.0,
                "detection_image_path": detection_path,
                "segmentation_image_path": segmentation_path,
                "segmentation_annotated_path": annotated_seg_path,
                "original_image_path": original_path,
            }
        except Exception as e:
            logging.error(f"Visual analysis failed: {e}", exc_info=True)
            raise

    # ---------- Knowledge base and reporting stay unchanged ----------
    def query_guidelines(self, query: str) -> str:
        try:
            vs = self.knowledge_base_cache.get("vector_store")
            if not vs:
                return "Knowledge base is not available."
            try:
                retriever = vs.as_retriever(search_kwargs={"k": 5})
                docs = retriever.get_relevant_documents(query)
            except Exception:
                retriever = vs.as_retriever(search_kwargs={"k": 5})
                docs = retriever.invoke(query)
            lines: List[str] = []
            for d in docs:
                src = (d.metadata or {}).get("source", "N/A")
                txt = (d.page_content or "")[:300]
                lines.append(f"Source: {src}\nContent: {txt}...")
            return "\n\n".join(lines) if lines else "No relevant guideline snippets found."
        except Exception as e:
            logging.warning(f"Guidelines query failed: {e}")
            return f"Guidelines query failed: {str(e)}"

    def _generate_fallback_report(self, patient_info: str, visual_results: Dict, guideline_context: str) -> str:
        return f"""# 🩺 SmartHeal AI - Comprehensive Wound Analysis Report

## πŸ“‹ Patient Information
{patient_info}

## πŸ” Visual Analysis Results
- **Wound Type**: {visual_results.get('wound_type', 'Unknown')}
- **Dimensions**: {visual_results.get('length_cm', 0)} cm Γ— {visual_results.get('breadth_cm', 0)} cm
- **Surface Area**: {visual_results.get('surface_area_cm2', 0)} cmΒ²
- **Detection Confidence**: {visual_results.get('detection_confidence', 0):.1%}
- **Calibration**: {visual_results.get('px_per_cm','?')} px/cm ({(visual_results.get('calibration_meta') or {}).get('used','default')})

## πŸ“Š Analysis Images
- **Original**: {visual_results.get('original_image_path', 'N/A')}
- **Detection**: {visual_results.get('detection_image_path', 'N/A')}
- **Segmentation**: {visual_results.get('segmentation_image_path', 'N/A')}
- **Annotated**: {visual_results.get('segmentation_annotated_path', 'N/A')}

## 🎯 Clinical Summary
Automated analysis provides quantitative measurements; verify via clinical examination.

## πŸ’Š Recommendations
- Cleanse wound gently; select dressing per exudate/infection risk
- Debride necrotic tissue if indicated (clinical decision)
- Document with serial photos and measurements

## πŸ“… Monitoring
- Daily in week 1, then every 2–3 days (or as indicated)
- Weekly progress review

## πŸ“š Guideline Context
{(guideline_context or '')[:800]}{"..." if guideline_context and len(guideline_context) > 800 else ''}

**Disclaimer:** Automated, for decision support only. Verify clinically.
"""

    def generate_final_report(
        self,
        patient_info: str,
        visual_results: Dict,
        guideline_context: str,
        image_pil: Image.Image,
        max_new_tokens: Optional[int] = None,
    ) -> str:
        try:
            report = generate_medgemma_report(
                patient_info, visual_results, guideline_context, image_pil, max_new_tokens
            )
            if report and report.strip() and not report.startswith(("⚠️", "❌")):
                return report
            logging.warning("MedGemma unavailable/invalid; using fallback.")
            return self._generate_fallback_report(patient_info, visual_results, guideline_context)
        except Exception as e:
            logging.error(f"Report generation failed: {e}")
            return self._generate_fallback_report(patient_info, visual_results, guideline_context)

    def save_and_commit_image(self, image_pil: Image.Image) -> str:
        try:
            os.makedirs(self.uploads_dir, exist_ok=True)
            ts = datetime.now().strftime("%Y%m%d_%H%M%S")
            filename = f"{ts}.png"
            path = os.path.join(self.uploads_dir, filename)
            image_pil.convert("RGB").save(path)
            logging.info(f"βœ… Image saved locally: {path}")

            if HF_TOKEN and DATASET_ID:
                try:
                    HfApi, HfFolder = _import_hf_hub()
                    HfFolder.save_token(HF_TOKEN)
                    api = HfApi()
                    api.upload_file(
                        path_or_fileobj=path,
                        path_in_repo=f"images/{filename}",
                        repo_id=DATASET_ID,
                        repo_type="dataset",
                        token=HF_TOKEN,
                        commit_message=f"Upload wound image: {filename}",
                    )
                    logging.info("βœ… Image committed to HF dataset")
                except Exception as e:
                    logging.warning(f"HF upload failed: {e}")

            return path
        except Exception as e:
            logging.error(f"Failed to save/commit image: {e}")
            return ""

    def full_analysis_pipeline(self, image_pil: Image.Image, questionnaire_data: Dict) -> Dict:
        try:
            saved_path = self.save_and_commit_image(image_pil)
            visual_results = self.perform_visual_analysis(image_pil)

            pi = questionnaire_data or {}
            patient_info = (
                f"Age: {pi.get('age','N/A')}, "
                f"Diabetic: {pi.get('diabetic','N/A')}, "
                f"Allergies: {pi.get('allergies','N/A')}, "
                f"Date of Wound: {pi.get('date_of_injury','N/A')}, "
                f"Professional Care: {pi.get('professional_care','N/A')}, "
                f"Oozing/Bleeding: {pi.get('oozing_bleeding','N/A')}, "
                f"Infection: {pi.get('infection','N/A')}, "
                f"Moisture: {pi.get('moisture','N/A')}"
            )

            query = (
                f"best practices for managing a {visual_results.get('wound_type','Unknown')} "
                f"with moisture '{pi.get('moisture','unknown')}' and infection '{pi.get('infection','unknown')}' "
                f"in a diabetic status '{pi.get('diabetic','unknown')}'"
            )
            guideline_context = self.query_guidelines(query)

            report = self.generate_final_report(patient_info, visual_results, guideline_context, image_pil)

            return {
                "success": True,
                "visual_analysis": visual_results,
                "report": report,
                "saved_image_path": saved_path,
                "guideline_context": (guideline_context or "")[:500] + (
                    "..." if guideline_context and len(guideline_context) > 500 else ""
                ),
            }
        except Exception as e:
            logging.error(f"Pipeline error: {e}")
            return {
                "success": False,
                "error": str(e),
                "visual_analysis": {},
                "report": f"Analysis failed: {str(e)}",
                "saved_image_path": None,
                "guideline_context": "",
            }

    def analyze_wound(self, image, questionnaire_data: Dict) -> Dict:
        try:
            if isinstance(image, str):
                if not os.path.exists(image):
                    raise ValueError(f"Image file not found: {image}")
                image_pil = Image.open(image)
            elif isinstance(image, Image.Image):
                image_pil = image
            elif isinstance(image, np.ndarray):
                image_pil = Image.fromarray(image)
            else:
                raise ValueError(f"Unsupported image type: {type(image)}")

            return self.full_analysis_pipeline(image_pil, questionnaire_data or {})
        except Exception as e:
            logging.error(f"Wound analysis error: {e}")
            return {
                "success": False,
                "error": str(e),
                "visual_analysis": {},
                "report": f"Analysis initialization failed: {str(e)}",
                "saved_image_path": None,
                "guideline_context": "",
            }