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File size: 61,224 Bytes
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1420 1421 1422 1423 1424 1425 1426 1427 1428 | {
"Objective": [
"activity",
"absorption",
"distribution",
"metabolism",
"excretion",
"toxicity",
"general physical properties"
],
"ImprovementAnticipationBool": [
"0-1",
"1-0",
"0-0"
],
"ImprovementAnticipationSeq": [
"(-inf, -10.5]",
"(-10.5, -8.5]",
"(-8.5, -6.5]",
"(-6.5, -4.5]",
"(-4.5, -2.5]",
"(-2.5, -1.5]",
"(-1.5, -1.0]",
"(-1.0, -0.5]",
"(-0.5, 0.0]",
"(0.0, 0.5]",
"(0.5, 1.0]",
"(1.0, 1.5]",
"(1.5, 2.5]",
"(2.5, 4.5]",
"(4.5, 6.5]",
"(6.5, 8.5]",
"(8.5, 10.5]",
"(10.5, inf]"
],
"Metrics": {
"activity": [
"IC50",
"Ki",
"Kd",
"EC50"
],
"absorption": [
"Drug uptake",
"Papp",
"permeability",
"F",
"Fu",
"Tmax",
"Cmax",
"lipophilicity_astrazeneca",
"solubility_aqsoldb",
"hydrationfreeenergy_freesolv",
"caco2_wang",
"pampa_ncats",
"hia_hou",
"pgp_broccatelli",
"bioavailability_ma"
],
"distribution": [
"Vdss",
"Cp",
"vdss_lombardo",
"bbb_martins",
"ppbr_az"
],
"metabolism": [
"Drug metabolism",
"LogD",
"LogP",
"cyp2c19_veith",
"cyp2d6_veith",
"cyp3a4_veith",
"cyp1a2_veith",
"cyp2c9_veith",
"cyp2c9_substrate_carbonmangels",
"cyp2d6_substrate_carbonmangels",
"cyp3a4_substrate_carbonmangels"
],
"excretion": [
"AUC",
"CL",
"FC",
"half_life_obach",
"clearance_hepatocyte_az",
"clearance_microsome_az"
],
"toxicity": [
"Stability",
"LD50",
"LC50",
"T1/2",
"tox21-NR-AR",
"tox21-NR-AR-LBD",
"tox21-NR-AhR",
"tox21-NR-Aromatase",
"tox21-NR-ER",
"tox21-NR-ER-LBD",
"tox21-NR-PPAR-gamma",
"tox21-SR-ARE",
"tox21-SR-ATAD5",
"tox21-SR-HSE",
"tox21-SR-MMP",
"tox21-SR-p53",
"toxcast-ACEA_T47D_80hr_Negative",
"toxcast-ACEA_T47D_80hr_Positive",
"toxcast-APR_HepG2_CellCycleArrest_24h_dn",
"toxcast-APR_HepG2_CellCycleArrest_24h_up",
"toxcast-APR_HepG2_CellCycleArrest_72h_dn",
"toxcast-APR_HepG2_CellLoss_24h_dn",
"toxcast-APR_HepG2_CellLoss_72h_dn",
"toxcast-APR_HepG2_MicrotubuleCSK_24h_dn",
"toxcast-APR_HepG2_MicrotubuleCSK_24h_up",
"toxcast-APR_HepG2_MicrotubuleCSK_72h_dn",
"toxcast-APR_HepG2_MicrotubuleCSK_72h_up",
"toxcast-APR_HepG2_MitoMass_24h_dn",
"toxcast-APR_HepG2_MitoMass_24h_up",
"toxcast-APR_HepG2_MitoMass_72h_dn",
"toxcast-APR_HepG2_MitoMass_72h_up",
"toxcast-APR_HepG2_MitoMembPot_1h_dn",
"toxcast-APR_HepG2_MitoMembPot_24h_dn",
"toxcast-APR_HepG2_MitoMembPot_72h_dn",
"toxcast-APR_HepG2_MitoticArrest_24h_up",
"toxcast-APR_HepG2_MitoticArrest_72h_up",
"toxcast-APR_HepG2_NuclearSize_24h_dn",
"toxcast-APR_HepG2_NuclearSize_72h_dn",
"toxcast-APR_HepG2_NuclearSize_72h_up",
"toxcast-APR_HepG2_OxidativeStress_24h_up",
"toxcast-APR_HepG2_OxidativeStress_72h_up",
"toxcast-APR_HepG2_StressKinase_1h_up",
"toxcast-APR_HepG2_StressKinase_24h_up",
"toxcast-APR_HepG2_StressKinase_72h_up",
"toxcast-APR_HepG2_p53Act_24h_up",
"toxcast-APR_HepG2_p53Act_72h_up",
"toxcast-APR_Hepat_Apoptosis_24hr_up",
"toxcast-APR_Hepat_Apoptosis_48hr_up",
"toxcast-APR_Hepat_CellLoss_24hr_dn",
"toxcast-APR_Hepat_CellLoss_48hr_dn",
"toxcast-APR_Hepat_DNADamage_24hr_up",
"toxcast-APR_Hepat_DNADamage_48hr_up",
"toxcast-APR_Hepat_DNATexture_24hr_up",
"toxcast-APR_Hepat_DNATexture_48hr_up",
"toxcast-APR_Hepat_MitoFxnI_1hr_dn",
"toxcast-APR_Hepat_MitoFxnI_24hr_dn",
"toxcast-APR_Hepat_MitoFxnI_48hr_dn",
"toxcast-APR_Hepat_NuclearSize_24hr_dn",
"toxcast-APR_Hepat_NuclearSize_48hr_dn",
"toxcast-APR_Hepat_Steatosis_24hr_up",
"toxcast-APR_Hepat_Steatosis_48hr_up",
"toxcast-ATG_AP_1_CIS_dn",
"toxcast-ATG_AP_1_CIS_up",
"toxcast-ATG_AP_2_CIS_dn",
"toxcast-ATG_AP_2_CIS_up",
"toxcast-ATG_AR_TRANS_dn",
"toxcast-ATG_AR_TRANS_up",
"toxcast-ATG_Ahr_CIS_dn",
"toxcast-ATG_Ahr_CIS_up",
"toxcast-ATG_BRE_CIS_dn",
"toxcast-ATG_BRE_CIS_up",
"toxcast-ATG_CAR_TRANS_dn",
"toxcast-ATG_CAR_TRANS_up",
"toxcast-ATG_CMV_CIS_dn",
"toxcast-ATG_CMV_CIS_up",
"toxcast-ATG_CRE_CIS_dn",
"toxcast-ATG_CRE_CIS_up",
"toxcast-ATG_C_EBP_CIS_dn",
"toxcast-ATG_C_EBP_CIS_up",
"toxcast-ATG_DR4_LXR_CIS_dn",
"toxcast-ATG_DR4_LXR_CIS_up",
"toxcast-ATG_DR5_CIS_dn",
"toxcast-ATG_DR5_CIS_up",
"toxcast-ATG_E2F_CIS_dn",
"toxcast-ATG_E2F_CIS_up",
"toxcast-ATG_EGR_CIS_up",
"toxcast-ATG_ERE_CIS_dn",
"toxcast-ATG_ERE_CIS_up",
"toxcast-ATG_ERRa_TRANS_dn",
"toxcast-ATG_ERRg_TRANS_dn",
"toxcast-ATG_ERRg_TRANS_up",
"toxcast-ATG_ERa_TRANS_up",
"toxcast-ATG_E_Box_CIS_dn",
"toxcast-ATG_E_Box_CIS_up",
"toxcast-ATG_Ets_CIS_dn",
"toxcast-ATG_Ets_CIS_up",
"toxcast-ATG_FXR_TRANS_up",
"toxcast-ATG_FoxA2_CIS_dn",
"toxcast-ATG_FoxA2_CIS_up",
"toxcast-ATG_FoxO_CIS_dn",
"toxcast-ATG_FoxO_CIS_up",
"toxcast-ATG_GAL4_TRANS_dn",
"toxcast-ATG_GATA_CIS_dn",
"toxcast-ATG_GATA_CIS_up",
"toxcast-ATG_GLI_CIS_dn",
"toxcast-ATG_GLI_CIS_up",
"toxcast-ATG_GRE_CIS_dn",
"toxcast-ATG_GRE_CIS_up",
"toxcast-ATG_GR_TRANS_dn",
"toxcast-ATG_GR_TRANS_up",
"toxcast-ATG_HIF1a_CIS_dn",
"toxcast-ATG_HIF1a_CIS_up",
"toxcast-ATG_HNF4a_TRANS_dn",
"toxcast-ATG_HNF4a_TRANS_up",
"toxcast-ATG_HNF6_CIS_dn",
"toxcast-ATG_HNF6_CIS_up",
"toxcast-ATG_HSE_CIS_dn",
"toxcast-ATG_HSE_CIS_up",
"toxcast-ATG_IR1_CIS_dn",
"toxcast-ATG_IR1_CIS_up",
"toxcast-ATG_ISRE_CIS_dn",
"toxcast-ATG_ISRE_CIS_up",
"toxcast-ATG_LXRa_TRANS_dn",
"toxcast-ATG_LXRa_TRANS_up",
"toxcast-ATG_LXRb_TRANS_dn",
"toxcast-ATG_LXRb_TRANS_up",
"toxcast-ATG_MRE_CIS_up",
"toxcast-ATG_M_06_TRANS_up",
"toxcast-ATG_M_19_CIS_dn",
"toxcast-ATG_M_19_TRANS_dn",
"toxcast-ATG_M_19_TRANS_up",
"toxcast-ATG_M_32_CIS_dn",
"toxcast-ATG_M_32_CIS_up",
"toxcast-ATG_M_32_TRANS_dn",
"toxcast-ATG_M_32_TRANS_up",
"toxcast-ATG_M_61_TRANS_up",
"toxcast-ATG_Myb_CIS_dn",
"toxcast-ATG_Myb_CIS_up",
"toxcast-ATG_Myc_CIS_dn",
"toxcast-ATG_Myc_CIS_up",
"toxcast-ATG_NFI_CIS_dn",
"toxcast-ATG_NFI_CIS_up",
"toxcast-ATG_NF_kB_CIS_dn",
"toxcast-ATG_NF_kB_CIS_up",
"toxcast-ATG_NRF1_CIS_dn",
"toxcast-ATG_NRF1_CIS_up",
"toxcast-ATG_NRF2_ARE_CIS_dn",
"toxcast-ATG_NRF2_ARE_CIS_up",
"toxcast-ATG_NURR1_TRANS_dn",
"toxcast-ATG_NURR1_TRANS_up",
"toxcast-ATG_Oct_MLP_CIS_dn",
"toxcast-ATG_Oct_MLP_CIS_up",
"toxcast-ATG_PBREM_CIS_dn",
"toxcast-ATG_PBREM_CIS_up",
"toxcast-ATG_PPARa_TRANS_dn",
"toxcast-ATG_PPARa_TRANS_up",
"toxcast-ATG_PPARd_TRANS_up",
"toxcast-ATG_PPARg_TRANS_up",
"toxcast-ATG_PPRE_CIS_dn",
"toxcast-ATG_PPRE_CIS_up",
"toxcast-ATG_PXRE_CIS_dn",
"toxcast-ATG_PXRE_CIS_up",
"toxcast-ATG_PXR_TRANS_dn",
"toxcast-ATG_PXR_TRANS_up",
"toxcast-ATG_Pax6_CIS_up",
"toxcast-ATG_RARa_TRANS_dn",
"toxcast-ATG_RARa_TRANS_up",
"toxcast-ATG_RARb_TRANS_dn",
"toxcast-ATG_RARb_TRANS_up",
"toxcast-ATG_RARg_TRANS_dn",
"toxcast-ATG_RARg_TRANS_up",
"toxcast-ATG_RORE_CIS_dn",
"toxcast-ATG_RORE_CIS_up",
"toxcast-ATG_RORb_TRANS_dn",
"toxcast-ATG_RORg_TRANS_dn",
"toxcast-ATG_RORg_TRANS_up",
"toxcast-ATG_RXRa_TRANS_dn",
"toxcast-ATG_RXRa_TRANS_up",
"toxcast-ATG_RXRb_TRANS_dn",
"toxcast-ATG_RXRb_TRANS_up",
"toxcast-ATG_SREBP_CIS_dn",
"toxcast-ATG_SREBP_CIS_up",
"toxcast-ATG_STAT3_CIS_dn",
"toxcast-ATG_STAT3_CIS_up",
"toxcast-ATG_Sox_CIS_dn",
"toxcast-ATG_Sox_CIS_up",
"toxcast-ATG_Sp1_CIS_dn",
"toxcast-ATG_Sp1_CIS_up",
"toxcast-ATG_TAL_CIS_dn",
"toxcast-ATG_TAL_CIS_up",
"toxcast-ATG_TA_CIS_dn",
"toxcast-ATG_TA_CIS_up",
"toxcast-ATG_TCF_b_cat_CIS_dn",
"toxcast-ATG_TCF_b_cat_CIS_up",
"toxcast-ATG_TGFb_CIS_dn",
"toxcast-ATG_TGFb_CIS_up",
"toxcast-ATG_THRa1_TRANS_dn",
"toxcast-ATG_THRa1_TRANS_up",
"toxcast-ATG_VDRE_CIS_dn",
"toxcast-ATG_VDRE_CIS_up",
"toxcast-ATG_VDR_TRANS_dn",
"toxcast-ATG_VDR_TRANS_up",
"toxcast-ATG_XTT_Cytotoxicity_up",
"toxcast-ATG_Xbp1_CIS_dn",
"toxcast-ATG_Xbp1_CIS_up",
"toxcast-ATG_p53_CIS_dn",
"toxcast-ATG_p53_CIS_up",
"toxcast-BSK_3C_Eselectin_down",
"toxcast-BSK_3C_HLADR_down",
"toxcast-BSK_3C_ICAM1_down",
"toxcast-BSK_3C_IL8_down",
"toxcast-BSK_3C_MCP1_down",
"toxcast-BSK_3C_MIG_down",
"toxcast-BSK_3C_Proliferation_down",
"toxcast-BSK_3C_SRB_down",
"toxcast-BSK_3C_Thrombomodulin_down",
"toxcast-BSK_3C_Thrombomodulin_up",
"toxcast-BSK_3C_TissueFactor_down",
"toxcast-BSK_3C_TissueFactor_up",
"toxcast-BSK_3C_VCAM1_down",
"toxcast-BSK_3C_Vis_down",
"toxcast-BSK_3C_uPAR_down",
"toxcast-BSK_4H_Eotaxin3_down",
"toxcast-BSK_4H_MCP1_down",
"toxcast-BSK_4H_Pselectin_down",
"toxcast-BSK_4H_Pselectin_up",
"toxcast-BSK_4H_SRB_down",
"toxcast-BSK_4H_VCAM1_down",
"toxcast-BSK_4H_VEGFRII_down",
"toxcast-BSK_4H_uPAR_down",
"toxcast-BSK_4H_uPAR_up",
"toxcast-BSK_BE3C_HLADR_down",
"toxcast-BSK_BE3C_IL1a_down",
"toxcast-BSK_BE3C_IP10_down",
"toxcast-BSK_BE3C_MIG_down",
"toxcast-BSK_BE3C_MMP1_down",
"toxcast-BSK_BE3C_MMP1_up",
"toxcast-BSK_BE3C_PAI1_down",
"toxcast-BSK_BE3C_SRB_down",
"toxcast-BSK_BE3C_TGFb1_down",
"toxcast-BSK_BE3C_tPA_down",
"toxcast-BSK_BE3C_uPAR_down",
"toxcast-BSK_BE3C_uPAR_up",
"toxcast-BSK_BE3C_uPA_down",
"toxcast-BSK_CASM3C_HLADR_down",
"toxcast-BSK_CASM3C_IL6_down",
"toxcast-BSK_CASM3C_IL6_up",
"toxcast-BSK_CASM3C_IL8_down",
"toxcast-BSK_CASM3C_LDLR_down",
"toxcast-BSK_CASM3C_LDLR_up",
"toxcast-BSK_CASM3C_MCP1_down",
"toxcast-BSK_CASM3C_MCP1_up",
"toxcast-BSK_CASM3C_MCSF_down",
"toxcast-BSK_CASM3C_MCSF_up",
"toxcast-BSK_CASM3C_MIG_down",
"toxcast-BSK_CASM3C_Proliferation_down",
"toxcast-BSK_CASM3C_Proliferation_up",
"toxcast-BSK_CASM3C_SAA_down",
"toxcast-BSK_CASM3C_SAA_up",
"toxcast-BSK_CASM3C_SRB_down",
"toxcast-BSK_CASM3C_Thrombomodulin_down",
"toxcast-BSK_CASM3C_Thrombomodulin_up",
"toxcast-BSK_CASM3C_TissueFactor_down",
"toxcast-BSK_CASM3C_VCAM1_down",
"toxcast-BSK_CASM3C_VCAM1_up",
"toxcast-BSK_CASM3C_uPAR_down",
"toxcast-BSK_CASM3C_uPAR_up",
"toxcast-BSK_KF3CT_ICAM1_down",
"toxcast-BSK_KF3CT_IL1a_down",
"toxcast-BSK_KF3CT_IP10_down",
"toxcast-BSK_KF3CT_IP10_up",
"toxcast-BSK_KF3CT_MCP1_down",
"toxcast-BSK_KF3CT_MCP1_up",
"toxcast-BSK_KF3CT_MMP9_down",
"toxcast-BSK_KF3CT_SRB_down",
"toxcast-BSK_KF3CT_TGFb1_down",
"toxcast-BSK_KF3CT_TIMP2_down",
"toxcast-BSK_KF3CT_uPA_down",
"toxcast-BSK_LPS_CD40_down",
"toxcast-BSK_LPS_Eselectin_down",
"toxcast-BSK_LPS_Eselectin_up",
"toxcast-BSK_LPS_IL1a_down",
"toxcast-BSK_LPS_IL1a_up",
"toxcast-BSK_LPS_IL8_down",
"toxcast-BSK_LPS_IL8_up",
"toxcast-BSK_LPS_MCP1_down",
"toxcast-BSK_LPS_MCSF_down",
"toxcast-BSK_LPS_PGE2_down",
"toxcast-BSK_LPS_PGE2_up",
"toxcast-BSK_LPS_SRB_down",
"toxcast-BSK_LPS_TNFa_down",
"toxcast-BSK_LPS_TNFa_up",
"toxcast-BSK_LPS_TissueFactor_down",
"toxcast-BSK_LPS_TissueFactor_up",
"toxcast-BSK_LPS_VCAM1_down",
"toxcast-BSK_SAg_CD38_down",
"toxcast-BSK_SAg_CD40_down",
"toxcast-BSK_SAg_CD69_down",
"toxcast-BSK_SAg_Eselectin_down",
"toxcast-BSK_SAg_Eselectin_up",
"toxcast-BSK_SAg_IL8_down",
"toxcast-BSK_SAg_IL8_up",
"toxcast-BSK_SAg_MCP1_down",
"toxcast-BSK_SAg_MIG_down",
"toxcast-BSK_SAg_PBMCCytotoxicity_down",
"toxcast-BSK_SAg_PBMCCytotoxicity_up",
"toxcast-BSK_SAg_Proliferation_down",
"toxcast-BSK_SAg_SRB_down",
"toxcast-BSK_hDFCGF_CollagenIII_down",
"toxcast-BSK_hDFCGF_EGFR_down",
"toxcast-BSK_hDFCGF_EGFR_up",
"toxcast-BSK_hDFCGF_IL8_down",
"toxcast-BSK_hDFCGF_IP10_down",
"toxcast-BSK_hDFCGF_MCSF_down",
"toxcast-BSK_hDFCGF_MIG_down",
"toxcast-BSK_hDFCGF_MMP1_down",
"toxcast-BSK_hDFCGF_MMP1_up",
"toxcast-BSK_hDFCGF_PAI1_down",
"toxcast-BSK_hDFCGF_Proliferation_down",
"toxcast-BSK_hDFCGF_SRB_down",
"toxcast-BSK_hDFCGF_TIMP1_down",
"toxcast-BSK_hDFCGF_VCAM1_down",
"toxcast-CEETOX_H295R_11DCORT_dn",
"toxcast-CEETOX_H295R_ANDR_dn",
"toxcast-CEETOX_H295R_CORTISOL_dn",
"toxcast-CEETOX_H295R_DOC_dn",
"toxcast-CEETOX_H295R_DOC_up",
"toxcast-CEETOX_H295R_ESTRADIOL_dn",
"toxcast-CEETOX_H295R_ESTRADIOL_up",
"toxcast-CEETOX_H295R_ESTRONE_dn",
"toxcast-CEETOX_H295R_ESTRONE_up",
"toxcast-CEETOX_H295R_OHPREG_up",
"toxcast-CEETOX_H295R_OHPROG_dn",
"toxcast-CEETOX_H295R_OHPROG_up",
"toxcast-CEETOX_H295R_PROG_up",
"toxcast-CEETOX_H295R_TESTO_dn",
"toxcast-CLD_ABCB1_48hr",
"toxcast-CLD_ABCG2_48hr",
"toxcast-CLD_CYP1A1_24hr",
"toxcast-CLD_CYP1A1_48hr",
"toxcast-CLD_CYP1A1_6hr",
"toxcast-CLD_CYP1A2_24hr",
"toxcast-CLD_CYP1A2_48hr",
"toxcast-CLD_CYP1A2_6hr",
"toxcast-CLD_CYP2B6_24hr",
"toxcast-CLD_CYP2B6_48hr",
"toxcast-CLD_CYP2B6_6hr",
"toxcast-CLD_CYP3A4_24hr",
"toxcast-CLD_CYP3A4_48hr",
"toxcast-CLD_CYP3A4_6hr",
"toxcast-CLD_GSTA2_48hr",
"toxcast-CLD_SULT2A_24hr",
"toxcast-CLD_SULT2A_48hr",
"toxcast-CLD_UGT1A1_24hr",
"toxcast-CLD_UGT1A1_48hr",
"toxcast-NCCT_HEK293T_CellTiterGLO",
"toxcast-NCCT_QuantiLum_inhib_2_dn",
"toxcast-NCCT_QuantiLum_inhib_dn",
"toxcast-NCCT_TPO_AUR_dn",
"toxcast-NCCT_TPO_GUA_dn",
"toxcast-NHEERL_ZF_144hpf_TERATOSCORE_up",
"toxcast-NVS_ADME_hCYP19A1",
"toxcast-NVS_ADME_hCYP1A1",
"toxcast-NVS_ADME_hCYP1A2",
"toxcast-NVS_ADME_hCYP2A6",
"toxcast-NVS_ADME_hCYP2B6",
"toxcast-NVS_ADME_hCYP2C19",
"toxcast-NVS_ADME_hCYP2C9",
"toxcast-NVS_ADME_hCYP2D6",
"toxcast-NVS_ADME_hCYP3A4",
"toxcast-NVS_ADME_hCYP4F12",
"toxcast-NVS_ADME_rCYP2C12",
"toxcast-NVS_ENZ_hAChE",
"toxcast-NVS_ENZ_hAMPKa1",
"toxcast-NVS_ENZ_hAurA",
"toxcast-NVS_ENZ_hBACE",
"toxcast-NVS_ENZ_hCASP5",
"toxcast-NVS_ENZ_hCK1D",
"toxcast-NVS_ENZ_hDUSP3",
"toxcast-NVS_ENZ_hES",
"toxcast-NVS_ENZ_hElastase",
"toxcast-NVS_ENZ_hFGFR1",
"toxcast-NVS_ENZ_hGSK3b",
"toxcast-NVS_ENZ_hMMP1",
"toxcast-NVS_ENZ_hMMP13",
"toxcast-NVS_ENZ_hMMP2",
"toxcast-NVS_ENZ_hMMP3",
"toxcast-NVS_ENZ_hMMP7",
"toxcast-NVS_ENZ_hMMP9",
"toxcast-NVS_ENZ_hPDE10",
"toxcast-NVS_ENZ_hPDE4A1",
"toxcast-NVS_ENZ_hPDE5",
"toxcast-NVS_ENZ_hPI3Ka",
"toxcast-NVS_ENZ_hPTEN",
"toxcast-NVS_ENZ_hPTPN11",
"toxcast-NVS_ENZ_hPTPN12",
"toxcast-NVS_ENZ_hPTPN13",
"toxcast-NVS_ENZ_hPTPN9",
"toxcast-NVS_ENZ_hPTPRC",
"toxcast-NVS_ENZ_hSIRT1",
"toxcast-NVS_ENZ_hSIRT2",
"toxcast-NVS_ENZ_hTrkA",
"toxcast-NVS_ENZ_hVEGFR2",
"toxcast-NVS_ENZ_oCOX1",
"toxcast-NVS_ENZ_oCOX2",
"toxcast-NVS_ENZ_rAChE",
"toxcast-NVS_ENZ_rCNOS",
"toxcast-NVS_ENZ_rMAOAC",
"toxcast-NVS_ENZ_rMAOAP",
"toxcast-NVS_ENZ_rMAOBC",
"toxcast-NVS_ENZ_rMAOBP",
"toxcast-NVS_ENZ_rabI2C",
"toxcast-NVS_GPCR_bAdoR_NonSelective",
"toxcast-NVS_GPCR_bDR_NonSelective",
"toxcast-NVS_GPCR_g5HT4",
"toxcast-NVS_GPCR_gH2",
"toxcast-NVS_GPCR_gLTB4",
"toxcast-NVS_GPCR_gLTD4",
"toxcast-NVS_GPCR_gMPeripheral_NonSelective",
"toxcast-NVS_GPCR_gOpiateK",
"toxcast-NVS_GPCR_h5HT2A",
"toxcast-NVS_GPCR_h5HT5A",
"toxcast-NVS_GPCR_h5HT6",
"toxcast-NVS_GPCR_h5HT7",
"toxcast-NVS_GPCR_hAT1",
"toxcast-NVS_GPCR_hAdoRA1",
"toxcast-NVS_GPCR_hAdoRA2a",
"toxcast-NVS_GPCR_hAdra2A",
"toxcast-NVS_GPCR_hAdra2C",
"toxcast-NVS_GPCR_hAdrb1",
"toxcast-NVS_GPCR_hAdrb2",
"toxcast-NVS_GPCR_hAdrb3",
"toxcast-NVS_GPCR_hDRD1",
"toxcast-NVS_GPCR_hDRD2s",
"toxcast-NVS_GPCR_hDRD4.4",
"toxcast-NVS_GPCR_hH1",
"toxcast-NVS_GPCR_hLTB4_BLT1",
"toxcast-NVS_GPCR_hM1",
"toxcast-NVS_GPCR_hM2",
"toxcast-NVS_GPCR_hM3",
"toxcast-NVS_GPCR_hM4",
"toxcast-NVS_GPCR_hNK2",
"toxcast-NVS_GPCR_hOpiate_D1",
"toxcast-NVS_GPCR_hOpiate_mu",
"toxcast-NVS_GPCR_hTXA2",
"toxcast-NVS_GPCR_p5HT2C",
"toxcast-NVS_GPCR_r5HT1_NonSelective",
"toxcast-NVS_GPCR_r5HT_NonSelective",
"toxcast-NVS_GPCR_rAdra1B",
"toxcast-NVS_GPCR_rAdra1_NonSelective",
"toxcast-NVS_GPCR_rAdra2_NonSelective",
"toxcast-NVS_GPCR_rAdrb_NonSelective",
"toxcast-NVS_GPCR_rNK1",
"toxcast-NVS_GPCR_rNK3",
"toxcast-NVS_GPCR_rOpiate_NonSelective",
"toxcast-NVS_GPCR_rOpiate_NonSelectiveNa",
"toxcast-NVS_GPCR_rSST",
"toxcast-NVS_GPCR_rTRH",
"toxcast-NVS_GPCR_rV1",
"toxcast-NVS_GPCR_rabPAF",
"toxcast-NVS_GPCR_rmAdra2B",
"toxcast-NVS_IC_hKhERGCh",
"toxcast-NVS_IC_rCaBTZCHL",
"toxcast-NVS_IC_rCaDHPRCh_L",
"toxcast-NVS_IC_rNaCh_site2",
"toxcast-NVS_LGIC_bGABARa1",
"toxcast-NVS_LGIC_h5HT3",
"toxcast-NVS_LGIC_hNNR_NBungSens",
"toxcast-NVS_LGIC_rGABAR_NonSelective",
"toxcast-NVS_LGIC_rNNR_BungSens",
"toxcast-NVS_MP_hPBR",
"toxcast-NVS_MP_rPBR",
"toxcast-NVS_NR_bER",
"toxcast-NVS_NR_bPR",
"toxcast-NVS_NR_cAR",
"toxcast-NVS_NR_hAR",
"toxcast-NVS_NR_hCAR_Antagonist",
"toxcast-NVS_NR_hER",
"toxcast-NVS_NR_hFXR_Agonist",
"toxcast-NVS_NR_hFXR_Antagonist",
"toxcast-NVS_NR_hGR",
"toxcast-NVS_NR_hPPARa",
"toxcast-NVS_NR_hPPARg",
"toxcast-NVS_NR_hPR",
"toxcast-NVS_NR_hPXR",
"toxcast-NVS_NR_hRAR_Antagonist",
"toxcast-NVS_NR_hRARa_Agonist",
"toxcast-NVS_NR_hTRa_Antagonist",
"toxcast-NVS_NR_mERa",
"toxcast-NVS_NR_rAR",
"toxcast-NVS_NR_rMR",
"toxcast-NVS_OR_gSIGMA_NonSelective",
"toxcast-NVS_TR_gDAT",
"toxcast-NVS_TR_hAdoT",
"toxcast-NVS_TR_hDAT",
"toxcast-NVS_TR_hNET",
"toxcast-NVS_TR_hSERT",
"toxcast-NVS_TR_rNET",
"toxcast-NVS_TR_rSERT",
"toxcast-NVS_TR_rVMAT2",
"toxcast-OT_AR_ARELUC_AG_1440",
"toxcast-OT_AR_ARSRC1_0480",
"toxcast-OT_AR_ARSRC1_0960",
"toxcast-OT_ER_ERaERa_0480",
"toxcast-OT_ER_ERaERa_1440",
"toxcast-OT_ER_ERaERb_0480",
"toxcast-OT_ER_ERaERb_1440",
"toxcast-OT_ER_ERbERb_0480",
"toxcast-OT_ER_ERbERb_1440",
"toxcast-OT_ERa_EREGFP_0120",
"toxcast-OT_ERa_EREGFP_0480",
"toxcast-OT_FXR_FXRSRC1_0480",
"toxcast-OT_FXR_FXRSRC1_1440",
"toxcast-OT_NURR1_NURR1RXRa_0480",
"toxcast-OT_NURR1_NURR1RXRa_1440",
"toxcast-TOX21_ARE_BLA_Agonist_ch1",
"toxcast-TOX21_ARE_BLA_Agonist_ch2",
"toxcast-TOX21_ARE_BLA_agonist_ratio",
"toxcast-TOX21_ARE_BLA_agonist_viability",
"toxcast-TOX21_AR_BLA_Agonist_ch1",
"toxcast-TOX21_AR_BLA_Agonist_ch2",
"toxcast-TOX21_AR_BLA_Agonist_ratio",
"toxcast-TOX21_AR_BLA_Antagonist_ch1",
"toxcast-TOX21_AR_BLA_Antagonist_ch2",
"toxcast-TOX21_AR_BLA_Antagonist_ratio",
"toxcast-TOX21_AR_BLA_Antagonist_viability",
"toxcast-TOX21_AR_LUC_MDAKB2_Agonist",
"toxcast-TOX21_AR_LUC_MDAKB2_Antagonist",
"toxcast-TOX21_AR_LUC_MDAKB2_Antagonist2",
"toxcast-TOX21_AhR_LUC_Agonist",
"toxcast-TOX21_Aromatase_Inhibition",
"toxcast-TOX21_AutoFluor_HEK293_Cell_blue",
"toxcast-TOX21_AutoFluor_HEK293_Media_blue",
"toxcast-TOX21_AutoFluor_HEPG2_Cell_blue",
"toxcast-TOX21_AutoFluor_HEPG2_Cell_green",
"toxcast-TOX21_AutoFluor_HEPG2_Media_blue",
"toxcast-TOX21_AutoFluor_HEPG2_Media_green",
"toxcast-TOX21_ELG1_LUC_Agonist",
"toxcast-TOX21_ERa_BLA_Agonist_ch1",
"toxcast-TOX21_ERa_BLA_Agonist_ch2",
"toxcast-TOX21_ERa_BLA_Agonist_ratio",
"toxcast-TOX21_ERa_BLA_Antagonist_ch1",
"toxcast-TOX21_ERa_BLA_Antagonist_ch2",
"toxcast-TOX21_ERa_BLA_Antagonist_ratio",
"toxcast-TOX21_ERa_BLA_Antagonist_viability",
"toxcast-TOX21_ERa_LUC_BG1_Agonist",
"toxcast-TOX21_ERa_LUC_BG1_Antagonist",
"toxcast-TOX21_ESRE_BLA_ch1",
"toxcast-TOX21_ESRE_BLA_ch2",
"toxcast-TOX21_ESRE_BLA_ratio",
"toxcast-TOX21_ESRE_BLA_viability",
"toxcast-TOX21_FXR_BLA_Antagonist_ch1",
"toxcast-TOX21_FXR_BLA_Antagonist_ch2",
"toxcast-TOX21_FXR_BLA_agonist_ch2",
"toxcast-TOX21_FXR_BLA_agonist_ratio",
"toxcast-TOX21_FXR_BLA_antagonist_ratio",
"toxcast-TOX21_FXR_BLA_antagonist_viability",
"toxcast-TOX21_GR_BLA_Agonist_ch1",
"toxcast-TOX21_GR_BLA_Agonist_ch2",
"toxcast-TOX21_GR_BLA_Agonist_ratio",
"toxcast-TOX21_GR_BLA_Antagonist_ch2",
"toxcast-TOX21_GR_BLA_Antagonist_ratio",
"toxcast-TOX21_GR_BLA_Antagonist_viability",
"toxcast-TOX21_HSE_BLA_agonist_ch1",
"toxcast-TOX21_HSE_BLA_agonist_ch2",
"toxcast-TOX21_HSE_BLA_agonist_ratio",
"toxcast-TOX21_HSE_BLA_agonist_viability",
"toxcast-TOX21_MMP_ratio_down",
"toxcast-TOX21_MMP_ratio_up",
"toxcast-TOX21_MMP_viability",
"toxcast-TOX21_NFkB_BLA_agonist_ch1",
"toxcast-TOX21_NFkB_BLA_agonist_ch2",
"toxcast-TOX21_NFkB_BLA_agonist_ratio",
"toxcast-TOX21_NFkB_BLA_agonist_viability",
"toxcast-TOX21_PPARd_BLA_Agonist_viability",
"toxcast-TOX21_PPARd_BLA_Antagonist_ch1",
"toxcast-TOX21_PPARd_BLA_agonist_ch1",
"toxcast-TOX21_PPARd_BLA_agonist_ch2",
"toxcast-TOX21_PPARd_BLA_agonist_ratio",
"toxcast-TOX21_PPARd_BLA_antagonist_ratio",
"toxcast-TOX21_PPARd_BLA_antagonist_viability",
"toxcast-TOX21_PPARg_BLA_Agonist_ch1",
"toxcast-TOX21_PPARg_BLA_Agonist_ch2",
"toxcast-TOX21_PPARg_BLA_Agonist_ratio",
"toxcast-TOX21_PPARg_BLA_Antagonist_ch1",
"toxcast-TOX21_PPARg_BLA_antagonist_ratio",
"toxcast-TOX21_PPARg_BLA_antagonist_viability",
"toxcast-TOX21_TR_LUC_GH3_Agonist",
"toxcast-TOX21_TR_LUC_GH3_Antagonist",
"toxcast-TOX21_VDR_BLA_Agonist_viability",
"toxcast-TOX21_VDR_BLA_Antagonist_ch1",
"toxcast-TOX21_VDR_BLA_agonist_ch2",
"toxcast-TOX21_VDR_BLA_agonist_ratio",
"toxcast-TOX21_VDR_BLA_antagonist_ratio",
"toxcast-TOX21_VDR_BLA_antagonist_viability",
"toxcast-TOX21_p53_BLA_p1_ch1",
"toxcast-TOX21_p53_BLA_p1_ch2",
"toxcast-TOX21_p53_BLA_p1_ratio",
"toxcast-TOX21_p53_BLA_p1_viability",
"toxcast-TOX21_p53_BLA_p2_ch1",
"toxcast-TOX21_p53_BLA_p2_ch2",
"toxcast-TOX21_p53_BLA_p2_ratio",
"toxcast-TOX21_p53_BLA_p2_viability",
"toxcast-TOX21_p53_BLA_p3_ch1",
"toxcast-TOX21_p53_BLA_p3_ch2",
"toxcast-TOX21_p53_BLA_p3_ratio",
"toxcast-TOX21_p53_BLA_p3_viability",
"toxcast-TOX21_p53_BLA_p4_ch1",
"toxcast-TOX21_p53_BLA_p4_ch2",
"toxcast-TOX21_p53_BLA_p4_ratio",
"toxcast-TOX21_p53_BLA_p4_viability",
"toxcast-TOX21_p53_BLA_p5_ch1",
"toxcast-TOX21_p53_BLA_p5_ch2",
"toxcast-TOX21_p53_BLA_p5_ratio",
"toxcast-TOX21_p53_BLA_p5_viability",
"toxcast-Tanguay_ZF_120hpf_AXIS_up",
"toxcast-Tanguay_ZF_120hpf_ActivityScore",
"toxcast-Tanguay_ZF_120hpf_BRAI_up",
"toxcast-Tanguay_ZF_120hpf_CFIN_up",
"toxcast-Tanguay_ZF_120hpf_CIRC_up",
"toxcast-Tanguay_ZF_120hpf_EYE_up",
"toxcast-Tanguay_ZF_120hpf_JAW_up",
"toxcast-Tanguay_ZF_120hpf_MORT_up",
"toxcast-Tanguay_ZF_120hpf_OTIC_up",
"toxcast-Tanguay_ZF_120hpf_PE_up",
"toxcast-Tanguay_ZF_120hpf_PFIN_up",
"toxcast-Tanguay_ZF_120hpf_PIG_up",
"toxcast-Tanguay_ZF_120hpf_SNOU_up",
"toxcast-Tanguay_ZF_120hpf_SOMI_up",
"toxcast-Tanguay_ZF_120hpf_SWIM_up",
"toxcast-Tanguay_ZF_120hpf_TRUN_up",
"toxcast-Tanguay_ZF_120hpf_TR_up",
"toxcast-Tanguay_ZF_120hpf_YSE_up",
"clintox",
"herg",
"herg_central-hERG_at_1uM",
"herg_central-hERG_at_10uM",
"herg_central-hERG_inhib",
"dili",
"skin_reaction",
"ames",
"carcinogens_lagunin",
"ld50_zhu"
],
"general physical properties": [
"solubility",
"Thermal melting change",
"pKa"
]
},
"BoolOrSeq": {
"T1-2": "seq",
"F": "bool",
"permeability": "seq",
"Stability": "seq",
"Drug metabolism": "seq",
"Cp": "seq",
"Cmax": "seq",
"FC": "seq",
"CL": "seq",
"Tmax": "bool",
"LD50": "seq",
"EC50": "seq",
"Drug uptake": "seq",
"Thermal melting change": "seq",
"solubility": "bool",
"LogD": "bool",
"LogP": "bool",
"Fu": "bool",
"pKa": "bool",
"Kd": "seq",
"Vdss": "bool",
"AUC": "seq",
"Ki": "seq",
"IC50": "seq",
"Papp": "seq",
"LC50": "seq",
"lipophilicity_astrazeneca": "seq",
"solubility_aqsoldb": "seq",
"hydrationfreeenergy_freesolv": "seq",
"caco2_wang": "seq",
"pampa_ncats": "bool",
"hia_hou": "bool",
"pgp_broccatelli": "bool",
"bioavailability_ma": "bool",
"vdss_lombardo": "seq",
"cyp2c19_veith": "bool",
"cyp2d6_veith": "bool",
"cyp3a4_veith": "bool",
"cyp1a2_veith": "bool",
"cyp2c9_veith": "bool",
"cyp2c9_substrate_carbonmangels": "bool",
"cyp2d6_substrate_carbonmangels": "bool",
"cyp3a4_substrate_carbonmangels": "bool",
"bbb_martins": "bool",
"ppbr_az": "seq",
"half_life_obach": "seq",
"clearance_hepatocyte_az": "seq",
"clearance_microsome_az": "seq",
"tox21-NR-AR": "bool",
"tox21-NR-AR-LBD": "bool",
"tox21-NR-AhR": "bool",
"tox21-NR-Aromatase": "bool",
"tox21-NR-ER": "bool",
"tox21-NR-ER-LBD": "bool",
"tox21-NR-PPAR-gamma": "bool",
"tox21-SR-ARE": "bool",
"tox21-SR-ATAD5": "bool",
"tox21-SR-HSE": "bool",
"tox21-SR-MMP": "bool",
"tox21-SR-p53": "bool",
"toxcast-ACEA_T47D_80hr_Negative": "bool",
"toxcast-ACEA_T47D_80hr_Positive": "bool",
"toxcast-APR_HepG2_CellCycleArrest_24h_dn": "bool",
"toxcast-APR_HepG2_CellCycleArrest_24h_up": "bool",
"toxcast-APR_HepG2_CellCycleArrest_72h_dn": "bool",
"toxcast-APR_HepG2_CellLoss_24h_dn": "bool",
"toxcast-APR_HepG2_CellLoss_72h_dn": "bool",
"toxcast-APR_HepG2_MicrotubuleCSK_24h_dn": "bool",
"toxcast-APR_HepG2_MicrotubuleCSK_24h_up": "bool",
"toxcast-APR_HepG2_MicrotubuleCSK_72h_dn": "bool",
"toxcast-APR_HepG2_MicrotubuleCSK_72h_up": "bool",
"toxcast-APR_HepG2_MitoMass_24h_dn": "bool",
"toxcast-APR_HepG2_MitoMass_24h_up": "bool",
"toxcast-APR_HepG2_MitoMass_72h_dn": "bool",
"toxcast-APR_HepG2_MitoMass_72h_up": "bool",
"toxcast-APR_HepG2_MitoMembPot_1h_dn": "bool",
"toxcast-APR_HepG2_MitoMembPot_24h_dn": "bool",
"toxcast-APR_HepG2_MitoMembPot_72h_dn": "bool",
"toxcast-APR_HepG2_MitoticArrest_24h_up": "bool",
"toxcast-APR_HepG2_MitoticArrest_72h_up": "bool",
"toxcast-APR_HepG2_NuclearSize_24h_dn": "bool",
"toxcast-APR_HepG2_NuclearSize_72h_dn": "bool",
"toxcast-APR_HepG2_NuclearSize_72h_up": "bool",
"toxcast-APR_HepG2_OxidativeStress_24h_up": "bool",
"toxcast-APR_HepG2_OxidativeStress_72h_up": "bool",
"toxcast-APR_HepG2_StressKinase_1h_up": "bool",
"toxcast-APR_HepG2_StressKinase_24h_up": "bool",
"toxcast-APR_HepG2_StressKinase_72h_up": "bool",
"toxcast-APR_HepG2_p53Act_24h_up": "bool",
"toxcast-APR_HepG2_p53Act_72h_up": "bool",
"toxcast-APR_Hepat_Apoptosis_24hr_up": "bool",
"toxcast-APR_Hepat_Apoptosis_48hr_up": "bool",
"toxcast-APR_Hepat_CellLoss_24hr_dn": "bool",
"toxcast-APR_Hepat_CellLoss_48hr_dn": "bool",
"toxcast-APR_Hepat_DNADamage_24hr_up": "bool",
"toxcast-APR_Hepat_DNADamage_48hr_up": "bool",
"toxcast-APR_Hepat_DNATexture_24hr_up": "bool",
"toxcast-APR_Hepat_DNATexture_48hr_up": "bool",
"toxcast-APR_Hepat_MitoFxnI_1hr_dn": "bool",
"toxcast-APR_Hepat_MitoFxnI_24hr_dn": "bool",
"toxcast-APR_Hepat_MitoFxnI_48hr_dn": "bool",
"toxcast-APR_Hepat_NuclearSize_24hr_dn": "bool",
"toxcast-APR_Hepat_NuclearSize_48hr_dn": "bool",
"toxcast-APR_Hepat_Steatosis_24hr_up": "bool",
"toxcast-APR_Hepat_Steatosis_48hr_up": "bool",
"toxcast-ATG_AP_1_CIS_dn": "bool",
"toxcast-ATG_AP_1_CIS_up": "bool",
"toxcast-ATG_AP_2_CIS_dn": "bool",
"toxcast-ATG_AP_2_CIS_up": "bool",
"toxcast-ATG_AR_TRANS_dn": "bool",
"toxcast-ATG_AR_TRANS_up": "bool",
"toxcast-ATG_Ahr_CIS_dn": "bool",
"toxcast-ATG_Ahr_CIS_up": "bool",
"toxcast-ATG_BRE_CIS_dn": "bool",
"toxcast-ATG_BRE_CIS_up": "bool",
"toxcast-ATG_CAR_TRANS_dn": "bool",
"toxcast-ATG_CAR_TRANS_up": "bool",
"toxcast-ATG_CMV_CIS_dn": "bool",
"toxcast-ATG_CMV_CIS_up": "bool",
"toxcast-ATG_CRE_CIS_dn": "bool",
"toxcast-ATG_CRE_CIS_up": "bool",
"toxcast-ATG_C_EBP_CIS_dn": "bool",
"toxcast-ATG_C_EBP_CIS_up": "bool",
"toxcast-ATG_DR4_LXR_CIS_dn": "bool",
"toxcast-ATG_DR4_LXR_CIS_up": "bool",
"toxcast-ATG_DR5_CIS_dn": "bool",
"toxcast-ATG_DR5_CIS_up": "bool",
"toxcast-ATG_E2F_CIS_dn": "bool",
"toxcast-ATG_E2F_CIS_up": "bool",
"toxcast-ATG_EGR_CIS_up": "bool",
"toxcast-ATG_ERE_CIS_dn": "bool",
"toxcast-ATG_ERE_CIS_up": "bool",
"toxcast-ATG_ERRa_TRANS_dn": "bool",
"toxcast-ATG_ERRg_TRANS_dn": "bool",
"toxcast-ATG_ERRg_TRANS_up": "bool",
"toxcast-ATG_ERa_TRANS_up": "bool",
"toxcast-ATG_E_Box_CIS_dn": "bool",
"toxcast-ATG_E_Box_CIS_up": "bool",
"toxcast-ATG_Ets_CIS_dn": "bool",
"toxcast-ATG_Ets_CIS_up": "bool",
"toxcast-ATG_FXR_TRANS_up": "bool",
"toxcast-ATG_FoxA2_CIS_dn": "bool",
"toxcast-ATG_FoxA2_CIS_up": "bool",
"toxcast-ATG_FoxO_CIS_dn": "bool",
"toxcast-ATG_FoxO_CIS_up": "bool",
"toxcast-ATG_GAL4_TRANS_dn": "bool",
"toxcast-ATG_GATA_CIS_dn": "bool",
"toxcast-ATG_GATA_CIS_up": "bool",
"toxcast-ATG_GLI_CIS_dn": "bool",
"toxcast-ATG_GLI_CIS_up": "bool",
"toxcast-ATG_GRE_CIS_dn": "bool",
"toxcast-ATG_GRE_CIS_up": "bool",
"toxcast-ATG_GR_TRANS_dn": "bool",
"toxcast-ATG_GR_TRANS_up": "bool",
"toxcast-ATG_HIF1a_CIS_dn": "bool",
"toxcast-ATG_HIF1a_CIS_up": "bool",
"toxcast-ATG_HNF4a_TRANS_dn": "bool",
"toxcast-ATG_HNF4a_TRANS_up": "bool",
"toxcast-ATG_HNF6_CIS_dn": "bool",
"toxcast-ATG_HNF6_CIS_up": "bool",
"toxcast-ATG_HSE_CIS_dn": "bool",
"toxcast-ATG_HSE_CIS_up": "bool",
"toxcast-ATG_IR1_CIS_dn": "bool",
"toxcast-ATG_IR1_CIS_up": "bool",
"toxcast-ATG_ISRE_CIS_dn": "bool",
"toxcast-ATG_ISRE_CIS_up": "bool",
"toxcast-ATG_LXRa_TRANS_dn": "bool",
"toxcast-ATG_LXRa_TRANS_up": "bool",
"toxcast-ATG_LXRb_TRANS_dn": "bool",
"toxcast-ATG_LXRb_TRANS_up": "bool",
"toxcast-ATG_MRE_CIS_up": "bool",
"toxcast-ATG_M_06_TRANS_up": "bool",
"toxcast-ATG_M_19_CIS_dn": "bool",
"toxcast-ATG_M_19_TRANS_dn": "bool",
"toxcast-ATG_M_19_TRANS_up": "bool",
"toxcast-ATG_M_32_CIS_dn": "bool",
"toxcast-ATG_M_32_CIS_up": "bool",
"toxcast-ATG_M_32_TRANS_dn": "bool",
"toxcast-ATG_M_32_TRANS_up": "bool",
"toxcast-ATG_M_61_TRANS_up": "bool",
"toxcast-ATG_Myb_CIS_dn": "bool",
"toxcast-ATG_Myb_CIS_up": "bool",
"toxcast-ATG_Myc_CIS_dn": "bool",
"toxcast-ATG_Myc_CIS_up": "bool",
"toxcast-ATG_NFI_CIS_dn": "bool",
"toxcast-ATG_NFI_CIS_up": "bool",
"toxcast-ATG_NF_kB_CIS_dn": "bool",
"toxcast-ATG_NF_kB_CIS_up": "bool",
"toxcast-ATG_NRF1_CIS_dn": "bool",
"toxcast-ATG_NRF1_CIS_up": "bool",
"toxcast-ATG_NRF2_ARE_CIS_dn": "bool",
"toxcast-ATG_NRF2_ARE_CIS_up": "bool",
"toxcast-ATG_NURR1_TRANS_dn": "bool",
"toxcast-ATG_NURR1_TRANS_up": "bool",
"toxcast-ATG_Oct_MLP_CIS_dn": "bool",
"toxcast-ATG_Oct_MLP_CIS_up": "bool",
"toxcast-ATG_PBREM_CIS_dn": "bool",
"toxcast-ATG_PBREM_CIS_up": "bool",
"toxcast-ATG_PPARa_TRANS_dn": "bool",
"toxcast-ATG_PPARa_TRANS_up": "bool",
"toxcast-ATG_PPARd_TRANS_up": "bool",
"toxcast-ATG_PPARg_TRANS_up": "bool",
"toxcast-ATG_PPRE_CIS_dn": "bool",
"toxcast-ATG_PPRE_CIS_up": "bool",
"toxcast-ATG_PXRE_CIS_dn": "bool",
"toxcast-ATG_PXRE_CIS_up": "bool",
"toxcast-ATG_PXR_TRANS_dn": "bool",
"toxcast-ATG_PXR_TRANS_up": "bool",
"toxcast-ATG_Pax6_CIS_up": "bool",
"toxcast-ATG_RARa_TRANS_dn": "bool",
"toxcast-ATG_RARa_TRANS_up": "bool",
"toxcast-ATG_RARb_TRANS_dn": "bool",
"toxcast-ATG_RARb_TRANS_up": "bool",
"toxcast-ATG_RARg_TRANS_dn": "bool",
"toxcast-ATG_RARg_TRANS_up": "bool",
"toxcast-ATG_RORE_CIS_dn": "bool",
"toxcast-ATG_RORE_CIS_up": "bool",
"toxcast-ATG_RORb_TRANS_dn": "bool",
"toxcast-ATG_RORg_TRANS_dn": "bool",
"toxcast-ATG_RORg_TRANS_up": "bool",
"toxcast-ATG_RXRa_TRANS_dn": "bool",
"toxcast-ATG_RXRa_TRANS_up": "bool",
"toxcast-ATG_RXRb_TRANS_dn": "bool",
"toxcast-ATG_RXRb_TRANS_up": "bool",
"toxcast-ATG_SREBP_CIS_dn": "bool",
"toxcast-ATG_SREBP_CIS_up": "bool",
"toxcast-ATG_STAT3_CIS_dn": "bool",
"toxcast-ATG_STAT3_CIS_up": "bool",
"toxcast-ATG_Sox_CIS_dn": "bool",
"toxcast-ATG_Sox_CIS_up": "bool",
"toxcast-ATG_Sp1_CIS_dn": "bool",
"toxcast-ATG_Sp1_CIS_up": "bool",
"toxcast-ATG_TAL_CIS_dn": "bool",
"toxcast-ATG_TAL_CIS_up": "bool",
"toxcast-ATG_TA_CIS_dn": "bool",
"toxcast-ATG_TA_CIS_up": "bool",
"toxcast-ATG_TCF_b_cat_CIS_dn": "bool",
"toxcast-ATG_TCF_b_cat_CIS_up": "bool",
"toxcast-ATG_TGFb_CIS_dn": "bool",
"toxcast-ATG_TGFb_CIS_up": "bool",
"toxcast-ATG_THRa1_TRANS_dn": "bool",
"toxcast-ATG_THRa1_TRANS_up": "bool",
"toxcast-ATG_VDRE_CIS_dn": "bool",
"toxcast-ATG_VDRE_CIS_up": "bool",
"toxcast-ATG_VDR_TRANS_dn": "bool",
"toxcast-ATG_VDR_TRANS_up": "bool",
"toxcast-ATG_XTT_Cytotoxicity_up": "bool",
"toxcast-ATG_Xbp1_CIS_dn": "bool",
"toxcast-ATG_Xbp1_CIS_up": "bool",
"toxcast-ATG_p53_CIS_dn": "bool",
"toxcast-ATG_p53_CIS_up": "bool",
"toxcast-BSK_3C_Eselectin_down": "bool",
"toxcast-BSK_3C_HLADR_down": "bool",
"toxcast-BSK_3C_ICAM1_down": "bool",
"toxcast-BSK_3C_IL8_down": "bool",
"toxcast-BSK_3C_MCP1_down": "bool",
"toxcast-BSK_3C_MIG_down": "bool",
"toxcast-BSK_3C_Proliferation_down": "bool",
"toxcast-BSK_3C_SRB_down": "bool",
"toxcast-BSK_3C_Thrombomodulin_down": "bool",
"toxcast-BSK_3C_Thrombomodulin_up": "bool",
"toxcast-BSK_3C_TissueFactor_down": "bool",
"toxcast-BSK_3C_TissueFactor_up": "bool",
"toxcast-BSK_3C_VCAM1_down": "bool",
"toxcast-BSK_3C_Vis_down": "bool",
"toxcast-BSK_3C_uPAR_down": "bool",
"toxcast-BSK_4H_Eotaxin3_down": "bool",
"toxcast-BSK_4H_MCP1_down": "bool",
"toxcast-BSK_4H_Pselectin_down": "bool",
"toxcast-BSK_4H_Pselectin_up": "bool",
"toxcast-BSK_4H_SRB_down": "bool",
"toxcast-BSK_4H_VCAM1_down": "bool",
"toxcast-BSK_4H_VEGFRII_down": "bool",
"toxcast-BSK_4H_uPAR_down": "bool",
"toxcast-BSK_4H_uPAR_up": "bool",
"toxcast-BSK_BE3C_HLADR_down": "bool",
"toxcast-BSK_BE3C_IL1a_down": "bool",
"toxcast-BSK_BE3C_IP10_down": "bool",
"toxcast-BSK_BE3C_MIG_down": "bool",
"toxcast-BSK_BE3C_MMP1_down": "bool",
"toxcast-BSK_BE3C_MMP1_up": "bool",
"toxcast-BSK_BE3C_PAI1_down": "bool",
"toxcast-BSK_BE3C_SRB_down": "bool",
"toxcast-BSK_BE3C_TGFb1_down": "bool",
"toxcast-BSK_BE3C_tPA_down": "bool",
"toxcast-BSK_BE3C_uPAR_down": "bool",
"toxcast-BSK_BE3C_uPAR_up": "bool",
"toxcast-BSK_BE3C_uPA_down": "bool",
"toxcast-BSK_CASM3C_HLADR_down": "bool",
"toxcast-BSK_CASM3C_IL6_down": "bool",
"toxcast-BSK_CASM3C_IL6_up": "bool",
"toxcast-BSK_CASM3C_IL8_down": "bool",
"toxcast-BSK_CASM3C_LDLR_down": "bool",
"toxcast-BSK_CASM3C_LDLR_up": "bool",
"toxcast-BSK_CASM3C_MCP1_down": "bool",
"toxcast-BSK_CASM3C_MCP1_up": "bool",
"toxcast-BSK_CASM3C_MCSF_down": "bool",
"toxcast-BSK_CASM3C_MCSF_up": "bool",
"toxcast-BSK_CASM3C_MIG_down": "bool",
"toxcast-BSK_CASM3C_Proliferation_down": "bool",
"toxcast-BSK_CASM3C_Proliferation_up": "bool",
"toxcast-BSK_CASM3C_SAA_down": "bool",
"toxcast-BSK_CASM3C_SAA_up": "bool",
"toxcast-BSK_CASM3C_SRB_down": "bool",
"toxcast-BSK_CASM3C_Thrombomodulin_down": "bool",
"toxcast-BSK_CASM3C_Thrombomodulin_up": "bool",
"toxcast-BSK_CASM3C_TissueFactor_down": "bool",
"toxcast-BSK_CASM3C_VCAM1_down": "bool",
"toxcast-BSK_CASM3C_VCAM1_up": "bool",
"toxcast-BSK_CASM3C_uPAR_down": "bool",
"toxcast-BSK_CASM3C_uPAR_up": "bool",
"toxcast-BSK_KF3CT_ICAM1_down": "bool",
"toxcast-BSK_KF3CT_IL1a_down": "bool",
"toxcast-BSK_KF3CT_IP10_down": "bool",
"toxcast-BSK_KF3CT_IP10_up": "bool",
"toxcast-BSK_KF3CT_MCP1_down": "bool",
"toxcast-BSK_KF3CT_MCP1_up": "bool",
"toxcast-BSK_KF3CT_MMP9_down": "bool",
"toxcast-BSK_KF3CT_SRB_down": "bool",
"toxcast-BSK_KF3CT_TGFb1_down": "bool",
"toxcast-BSK_KF3CT_TIMP2_down": "bool",
"toxcast-BSK_KF3CT_uPA_down": "bool",
"toxcast-BSK_LPS_CD40_down": "bool",
"toxcast-BSK_LPS_Eselectin_down": "bool",
"toxcast-BSK_LPS_Eselectin_up": "bool",
"toxcast-BSK_LPS_IL1a_down": "bool",
"toxcast-BSK_LPS_IL1a_up": "bool",
"toxcast-BSK_LPS_IL8_down": "bool",
"toxcast-BSK_LPS_IL8_up": "bool",
"toxcast-BSK_LPS_MCP1_down": "bool",
"toxcast-BSK_LPS_MCSF_down": "bool",
"toxcast-BSK_LPS_PGE2_down": "bool",
"toxcast-BSK_LPS_PGE2_up": "bool",
"toxcast-BSK_LPS_SRB_down": "bool",
"toxcast-BSK_LPS_TNFa_down": "bool",
"toxcast-BSK_LPS_TNFa_up": "bool",
"toxcast-BSK_LPS_TissueFactor_down": "bool",
"toxcast-BSK_LPS_TissueFactor_up": "bool",
"toxcast-BSK_LPS_VCAM1_down": "bool",
"toxcast-BSK_SAg_CD38_down": "bool",
"toxcast-BSK_SAg_CD40_down": "bool",
"toxcast-BSK_SAg_CD69_down": "bool",
"toxcast-BSK_SAg_Eselectin_down": "bool",
"toxcast-BSK_SAg_Eselectin_up": "bool",
"toxcast-BSK_SAg_IL8_down": "bool",
"toxcast-BSK_SAg_IL8_up": "bool",
"toxcast-BSK_SAg_MCP1_down": "bool",
"toxcast-BSK_SAg_MIG_down": "bool",
"toxcast-BSK_SAg_PBMCCytotoxicity_down": "bool",
"toxcast-BSK_SAg_PBMCCytotoxicity_up": "bool",
"toxcast-BSK_SAg_Proliferation_down": "bool",
"toxcast-BSK_SAg_SRB_down": "bool",
"toxcast-BSK_hDFCGF_CollagenIII_down": "bool",
"toxcast-BSK_hDFCGF_EGFR_down": "bool",
"toxcast-BSK_hDFCGF_EGFR_up": "bool",
"toxcast-BSK_hDFCGF_IL8_down": "bool",
"toxcast-BSK_hDFCGF_IP10_down": "bool",
"toxcast-BSK_hDFCGF_MCSF_down": "bool",
"toxcast-BSK_hDFCGF_MIG_down": "bool",
"toxcast-BSK_hDFCGF_MMP1_down": "bool",
"toxcast-BSK_hDFCGF_MMP1_up": "bool",
"toxcast-BSK_hDFCGF_PAI1_down": "bool",
"toxcast-BSK_hDFCGF_Proliferation_down": "bool",
"toxcast-BSK_hDFCGF_SRB_down": "bool",
"toxcast-BSK_hDFCGF_TIMP1_down": "bool",
"toxcast-BSK_hDFCGF_VCAM1_down": "bool",
"toxcast-CEETOX_H295R_11DCORT_dn": "bool",
"toxcast-CEETOX_H295R_ANDR_dn": "bool",
"toxcast-CEETOX_H295R_CORTISOL_dn": "bool",
"toxcast-CEETOX_H295R_DOC_dn": "bool",
"toxcast-CEETOX_H295R_DOC_up": "bool",
"toxcast-CEETOX_H295R_ESTRADIOL_dn": "bool",
"toxcast-CEETOX_H295R_ESTRADIOL_up": "bool",
"toxcast-CEETOX_H295R_ESTRONE_dn": "bool",
"toxcast-CEETOX_H295R_ESTRONE_up": "bool",
"toxcast-CEETOX_H295R_OHPREG_up": "bool",
"toxcast-CEETOX_H295R_OHPROG_dn": "bool",
"toxcast-CEETOX_H295R_OHPROG_up": "bool",
"toxcast-CEETOX_H295R_PROG_up": "bool",
"toxcast-CEETOX_H295R_TESTO_dn": "bool",
"toxcast-CLD_ABCB1_48hr": "bool",
"toxcast-CLD_ABCG2_48hr": "bool",
"toxcast-CLD_CYP1A1_24hr": "bool",
"toxcast-CLD_CYP1A1_48hr": "bool",
"toxcast-CLD_CYP1A1_6hr": "bool",
"toxcast-CLD_CYP1A2_24hr": "bool",
"toxcast-CLD_CYP1A2_48hr": "bool",
"toxcast-CLD_CYP1A2_6hr": "bool",
"toxcast-CLD_CYP2B6_24hr": "bool",
"toxcast-CLD_CYP2B6_48hr": "bool",
"toxcast-CLD_CYP2B6_6hr": "bool",
"toxcast-CLD_CYP3A4_24hr": "bool",
"toxcast-CLD_CYP3A4_48hr": "bool",
"toxcast-CLD_CYP3A4_6hr": "bool",
"toxcast-CLD_GSTA2_48hr": "bool",
"toxcast-CLD_SULT2A_24hr": "bool",
"toxcast-CLD_SULT2A_48hr": "bool",
"toxcast-CLD_UGT1A1_24hr": "bool",
"toxcast-CLD_UGT1A1_48hr": "bool",
"toxcast-NCCT_HEK293T_CellTiterGLO": "bool",
"toxcast-NCCT_QuantiLum_inhib_2_dn": "bool",
"toxcast-NCCT_QuantiLum_inhib_dn": "bool",
"toxcast-NCCT_TPO_AUR_dn": "bool",
"toxcast-NCCT_TPO_GUA_dn": "bool",
"toxcast-NHEERL_ZF_144hpf_TERATOSCORE_up": "bool",
"toxcast-NVS_ADME_hCYP19A1": "bool",
"toxcast-NVS_ADME_hCYP1A1": "bool",
"toxcast-NVS_ADME_hCYP1A2": "bool",
"toxcast-NVS_ADME_hCYP2A6": "bool",
"toxcast-NVS_ADME_hCYP2B6": "bool",
"toxcast-NVS_ADME_hCYP2C19": "bool",
"toxcast-NVS_ADME_hCYP2C9": "bool",
"toxcast-NVS_ADME_hCYP2D6": "bool",
"toxcast-NVS_ADME_hCYP3A4": "bool",
"toxcast-NVS_ADME_hCYP4F12": "bool",
"toxcast-NVS_ADME_rCYP2C12": "bool",
"toxcast-NVS_ENZ_hAChE": "bool",
"toxcast-NVS_ENZ_hAMPKa1": "bool",
"toxcast-NVS_ENZ_hAurA": "bool",
"toxcast-NVS_ENZ_hBACE": "bool",
"toxcast-NVS_ENZ_hCASP5": "bool",
"toxcast-NVS_ENZ_hCK1D": "bool",
"toxcast-NVS_ENZ_hDUSP3": "bool",
"toxcast-NVS_ENZ_hES": "bool",
"toxcast-NVS_ENZ_hElastase": "bool",
"toxcast-NVS_ENZ_hFGFR1": "bool",
"toxcast-NVS_ENZ_hGSK3b": "bool",
"toxcast-NVS_ENZ_hMMP1": "bool",
"toxcast-NVS_ENZ_hMMP13": "bool",
"toxcast-NVS_ENZ_hMMP2": "bool",
"toxcast-NVS_ENZ_hMMP3": "bool",
"toxcast-NVS_ENZ_hMMP7": "bool",
"toxcast-NVS_ENZ_hMMP9": "bool",
"toxcast-NVS_ENZ_hPDE10": "bool",
"toxcast-NVS_ENZ_hPDE4A1": "bool",
"toxcast-NVS_ENZ_hPDE5": "bool",
"toxcast-NVS_ENZ_hPI3Ka": "bool",
"toxcast-NVS_ENZ_hPTEN": "bool",
"toxcast-NVS_ENZ_hPTPN11": "bool",
"toxcast-NVS_ENZ_hPTPN12": "bool",
"toxcast-NVS_ENZ_hPTPN13": "bool",
"toxcast-NVS_ENZ_hPTPN9": "bool",
"toxcast-NVS_ENZ_hPTPRC": "bool",
"toxcast-NVS_ENZ_hSIRT1": "bool",
"toxcast-NVS_ENZ_hSIRT2": "bool",
"toxcast-NVS_ENZ_hTrkA": "bool",
"toxcast-NVS_ENZ_hVEGFR2": "bool",
"toxcast-NVS_ENZ_oCOX1": "bool",
"toxcast-NVS_ENZ_oCOX2": "bool",
"toxcast-NVS_ENZ_rAChE": "bool",
"toxcast-NVS_ENZ_rCNOS": "bool",
"toxcast-NVS_ENZ_rMAOAC": "bool",
"toxcast-NVS_ENZ_rMAOAP": "bool",
"toxcast-NVS_ENZ_rMAOBC": "bool",
"toxcast-NVS_ENZ_rMAOBP": "bool",
"toxcast-NVS_ENZ_rabI2C": "bool",
"toxcast-NVS_GPCR_bAdoR_NonSelective": "bool",
"toxcast-NVS_GPCR_bDR_NonSelective": "bool",
"toxcast-NVS_GPCR_g5HT4": "bool",
"toxcast-NVS_GPCR_gH2": "bool",
"toxcast-NVS_GPCR_gLTB4": "bool",
"toxcast-NVS_GPCR_gLTD4": "bool",
"toxcast-NVS_GPCR_gMPeripheral_NonSelective": "bool",
"toxcast-NVS_GPCR_gOpiateK": "bool",
"toxcast-NVS_GPCR_h5HT2A": "bool",
"toxcast-NVS_GPCR_h5HT5A": "bool",
"toxcast-NVS_GPCR_h5HT6": "bool",
"toxcast-NVS_GPCR_h5HT7": "bool",
"toxcast-NVS_GPCR_hAT1": "bool",
"toxcast-NVS_GPCR_hAdoRA1": "bool",
"toxcast-NVS_GPCR_hAdoRA2a": "bool",
"toxcast-NVS_GPCR_hAdra2A": "bool",
"toxcast-NVS_GPCR_hAdra2C": "bool",
"toxcast-NVS_GPCR_hAdrb1": "bool",
"toxcast-NVS_GPCR_hAdrb2": "bool",
"toxcast-NVS_GPCR_hAdrb3": "bool",
"toxcast-NVS_GPCR_hDRD1": "bool",
"toxcast-NVS_GPCR_hDRD2s": "bool",
"toxcast-NVS_GPCR_hDRD4.4": "bool",
"toxcast-NVS_GPCR_hH1": "bool",
"toxcast-NVS_GPCR_hLTB4_BLT1": "bool",
"toxcast-NVS_GPCR_hM1": "bool",
"toxcast-NVS_GPCR_hM2": "bool",
"toxcast-NVS_GPCR_hM3": "bool",
"toxcast-NVS_GPCR_hM4": "bool",
"toxcast-NVS_GPCR_hNK2": "bool",
"toxcast-NVS_GPCR_hOpiate_D1": "bool",
"toxcast-NVS_GPCR_hOpiate_mu": "bool",
"toxcast-NVS_GPCR_hTXA2": "bool",
"toxcast-NVS_GPCR_p5HT2C": "bool",
"toxcast-NVS_GPCR_r5HT1_NonSelective": "bool",
"toxcast-NVS_GPCR_r5HT_NonSelective": "bool",
"toxcast-NVS_GPCR_rAdra1B": "bool",
"toxcast-NVS_GPCR_rAdra1_NonSelective": "bool",
"toxcast-NVS_GPCR_rAdra2_NonSelective": "bool",
"toxcast-NVS_GPCR_rAdrb_NonSelective": "bool",
"toxcast-NVS_GPCR_rNK1": "bool",
"toxcast-NVS_GPCR_rNK3": "bool",
"toxcast-NVS_GPCR_rOpiate_NonSelective": "bool",
"toxcast-NVS_GPCR_rOpiate_NonSelectiveNa": "bool",
"toxcast-NVS_GPCR_rSST": "bool",
"toxcast-NVS_GPCR_rTRH": "bool",
"toxcast-NVS_GPCR_rV1": "bool",
"toxcast-NVS_GPCR_rabPAF": "bool",
"toxcast-NVS_GPCR_rmAdra2B": "bool",
"toxcast-NVS_IC_hKhERGCh": "bool",
"toxcast-NVS_IC_rCaBTZCHL": "bool",
"toxcast-NVS_IC_rCaDHPRCh_L": "bool",
"toxcast-NVS_IC_rNaCh_site2": "bool",
"toxcast-NVS_LGIC_bGABARa1": "bool",
"toxcast-NVS_LGIC_h5HT3": "bool",
"toxcast-NVS_LGIC_hNNR_NBungSens": "bool",
"toxcast-NVS_LGIC_rGABAR_NonSelective": "bool",
"toxcast-NVS_LGIC_rNNR_BungSens": "bool",
"toxcast-NVS_MP_hPBR": "bool",
"toxcast-NVS_MP_rPBR": "bool",
"toxcast-NVS_NR_bER": "bool",
"toxcast-NVS_NR_bPR": "bool",
"toxcast-NVS_NR_cAR": "bool",
"toxcast-NVS_NR_hAR": "bool",
"toxcast-NVS_NR_hCAR_Antagonist": "bool",
"toxcast-NVS_NR_hER": "bool",
"toxcast-NVS_NR_hFXR_Agonist": "bool",
"toxcast-NVS_NR_hFXR_Antagonist": "bool",
"toxcast-NVS_NR_hGR": "bool",
"toxcast-NVS_NR_hPPARa": "bool",
"toxcast-NVS_NR_hPPARg": "bool",
"toxcast-NVS_NR_hPR": "bool",
"toxcast-NVS_NR_hPXR": "bool",
"toxcast-NVS_NR_hRAR_Antagonist": "bool",
"toxcast-NVS_NR_hRARa_Agonist": "bool",
"toxcast-NVS_NR_hTRa_Antagonist": "bool",
"toxcast-NVS_NR_mERa": "bool",
"toxcast-NVS_NR_rAR": "bool",
"toxcast-NVS_NR_rMR": "bool",
"toxcast-NVS_OR_gSIGMA_NonSelective": "bool",
"toxcast-NVS_TR_gDAT": "bool",
"toxcast-NVS_TR_hAdoT": "bool",
"toxcast-NVS_TR_hDAT": "bool",
"toxcast-NVS_TR_hNET": "bool",
"toxcast-NVS_TR_hSERT": "bool",
"toxcast-NVS_TR_rNET": "bool",
"toxcast-NVS_TR_rSERT": "bool",
"toxcast-NVS_TR_rVMAT2": "bool",
"toxcast-OT_AR_ARELUC_AG_1440": "bool",
"toxcast-OT_AR_ARSRC1_0480": "bool",
"toxcast-OT_AR_ARSRC1_0960": "bool",
"toxcast-OT_ER_ERaERa_0480": "bool",
"toxcast-OT_ER_ERaERa_1440": "bool",
"toxcast-OT_ER_ERaERb_0480": "bool",
"toxcast-OT_ER_ERaERb_1440": "bool",
"toxcast-OT_ER_ERbERb_0480": "bool",
"toxcast-OT_ER_ERbERb_1440": "bool",
"toxcast-OT_ERa_EREGFP_0120": "bool",
"toxcast-OT_ERa_EREGFP_0480": "bool",
"toxcast-OT_FXR_FXRSRC1_0480": "bool",
"toxcast-OT_FXR_FXRSRC1_1440": "bool",
"toxcast-OT_NURR1_NURR1RXRa_0480": "bool",
"toxcast-OT_NURR1_NURR1RXRa_1440": "bool",
"toxcast-TOX21_ARE_BLA_Agonist_ch1": "bool",
"toxcast-TOX21_ARE_BLA_Agonist_ch2": "bool",
"toxcast-TOX21_ARE_BLA_agonist_ratio": "bool",
"toxcast-TOX21_ARE_BLA_agonist_viability": "bool",
"toxcast-TOX21_AR_BLA_Agonist_ch1": "bool",
"toxcast-TOX21_AR_BLA_Agonist_ch2": "bool",
"toxcast-TOX21_AR_BLA_Agonist_ratio": "bool",
"toxcast-TOX21_AR_BLA_Antagonist_ch1": "bool",
"toxcast-TOX21_AR_BLA_Antagonist_ch2": "bool",
"toxcast-TOX21_AR_BLA_Antagonist_ratio": "bool",
"toxcast-TOX21_AR_BLA_Antagonist_viability": "bool",
"toxcast-TOX21_AR_LUC_MDAKB2_Agonist": "bool",
"toxcast-TOX21_AR_LUC_MDAKB2_Antagonist": "bool",
"toxcast-TOX21_AR_LUC_MDAKB2_Antagonist2": "bool",
"toxcast-TOX21_AhR_LUC_Agonist": "bool",
"toxcast-TOX21_Aromatase_Inhibition": "bool",
"toxcast-TOX21_AutoFluor_HEK293_Cell_blue": "bool",
"toxcast-TOX21_AutoFluor_HEK293_Media_blue": "bool",
"toxcast-TOX21_AutoFluor_HEPG2_Cell_blue": "bool",
"toxcast-TOX21_AutoFluor_HEPG2_Cell_green": "bool",
"toxcast-TOX21_AutoFluor_HEPG2_Media_blue": "bool",
"toxcast-TOX21_AutoFluor_HEPG2_Media_green": "bool",
"toxcast-TOX21_ELG1_LUC_Agonist": "bool",
"toxcast-TOX21_ERa_BLA_Agonist_ch1": "bool",
"toxcast-TOX21_ERa_BLA_Agonist_ch2": "bool",
"toxcast-TOX21_ERa_BLA_Agonist_ratio": "bool",
"toxcast-TOX21_ERa_BLA_Antagonist_ch1": "bool",
"toxcast-TOX21_ERa_BLA_Antagonist_ch2": "bool",
"toxcast-TOX21_ERa_BLA_Antagonist_ratio": "bool",
"toxcast-TOX21_ERa_BLA_Antagonist_viability": "bool",
"toxcast-TOX21_ERa_LUC_BG1_Agonist": "bool",
"toxcast-TOX21_ERa_LUC_BG1_Antagonist": "bool",
"toxcast-TOX21_ESRE_BLA_ch1": "bool",
"toxcast-TOX21_ESRE_BLA_ch2": "bool",
"toxcast-TOX21_ESRE_BLA_ratio": "bool",
"toxcast-TOX21_ESRE_BLA_viability": "bool",
"toxcast-TOX21_FXR_BLA_Antagonist_ch1": "bool",
"toxcast-TOX21_FXR_BLA_Antagonist_ch2": "bool",
"toxcast-TOX21_FXR_BLA_agonist_ch2": "bool",
"toxcast-TOX21_FXR_BLA_agonist_ratio": "bool",
"toxcast-TOX21_FXR_BLA_antagonist_ratio": "bool",
"toxcast-TOX21_FXR_BLA_antagonist_viability": "bool",
"toxcast-TOX21_GR_BLA_Agonist_ch1": "bool",
"toxcast-TOX21_GR_BLA_Agonist_ch2": "bool",
"toxcast-TOX21_GR_BLA_Agonist_ratio": "bool",
"toxcast-TOX21_GR_BLA_Antagonist_ch2": "bool",
"toxcast-TOX21_GR_BLA_Antagonist_ratio": "bool",
"toxcast-TOX21_GR_BLA_Antagonist_viability": "bool",
"toxcast-TOX21_HSE_BLA_agonist_ch1": "bool",
"toxcast-TOX21_HSE_BLA_agonist_ch2": "bool",
"toxcast-TOX21_HSE_BLA_agonist_ratio": "bool",
"toxcast-TOX21_HSE_BLA_agonist_viability": "bool",
"toxcast-TOX21_MMP_ratio_down": "bool",
"toxcast-TOX21_MMP_ratio_up": "bool",
"toxcast-TOX21_MMP_viability": "bool",
"toxcast-TOX21_NFkB_BLA_agonist_ch1": "bool",
"toxcast-TOX21_NFkB_BLA_agonist_ch2": "bool",
"toxcast-TOX21_NFkB_BLA_agonist_ratio": "bool",
"toxcast-TOX21_NFkB_BLA_agonist_viability": "bool",
"toxcast-TOX21_PPARd_BLA_Agonist_viability": "bool",
"toxcast-TOX21_PPARd_BLA_Antagonist_ch1": "bool",
"toxcast-TOX21_PPARd_BLA_agonist_ch1": "bool",
"toxcast-TOX21_PPARd_BLA_agonist_ch2": "bool",
"toxcast-TOX21_PPARd_BLA_agonist_ratio": "bool",
"toxcast-TOX21_PPARd_BLA_antagonist_ratio": "bool",
"toxcast-TOX21_PPARd_BLA_antagonist_viability": "bool",
"toxcast-TOX21_PPARg_BLA_Agonist_ch1": "bool",
"toxcast-TOX21_PPARg_BLA_Agonist_ch2": "bool",
"toxcast-TOX21_PPARg_BLA_Agonist_ratio": "bool",
"toxcast-TOX21_PPARg_BLA_Antagonist_ch1": "bool",
"toxcast-TOX21_PPARg_BLA_antagonist_ratio": "bool",
"toxcast-TOX21_PPARg_BLA_antagonist_viability": "bool",
"toxcast-TOX21_TR_LUC_GH3_Agonist": "bool",
"toxcast-TOX21_TR_LUC_GH3_Antagonist": "bool",
"toxcast-TOX21_VDR_BLA_Agonist_viability": "bool",
"toxcast-TOX21_VDR_BLA_Antagonist_ch1": "bool",
"toxcast-TOX21_VDR_BLA_agonist_ch2": "bool",
"toxcast-TOX21_VDR_BLA_agonist_ratio": "bool",
"toxcast-TOX21_VDR_BLA_antagonist_ratio": "bool",
"toxcast-TOX21_VDR_BLA_antagonist_viability": "bool",
"toxcast-TOX21_p53_BLA_p1_ch1": "bool",
"toxcast-TOX21_p53_BLA_p1_ch2": "bool",
"toxcast-TOX21_p53_BLA_p1_ratio": "bool",
"toxcast-TOX21_p53_BLA_p1_viability": "bool",
"toxcast-TOX21_p53_BLA_p2_ch1": "bool",
"toxcast-TOX21_p53_BLA_p2_ch2": "bool",
"toxcast-TOX21_p53_BLA_p2_ratio": "bool",
"toxcast-TOX21_p53_BLA_p2_viability": "bool",
"toxcast-TOX21_p53_BLA_p3_ch1": "bool",
"toxcast-TOX21_p53_BLA_p3_ch2": "bool",
"toxcast-TOX21_p53_BLA_p3_ratio": "bool",
"toxcast-TOX21_p53_BLA_p3_viability": "bool",
"toxcast-TOX21_p53_BLA_p4_ch1": "bool",
"toxcast-TOX21_p53_BLA_p4_ch2": "bool",
"toxcast-TOX21_p53_BLA_p4_ratio": "bool",
"toxcast-TOX21_p53_BLA_p4_viability": "bool",
"toxcast-TOX21_p53_BLA_p5_ch1": "bool",
"toxcast-TOX21_p53_BLA_p5_ch2": "bool",
"toxcast-TOX21_p53_BLA_p5_ratio": "bool",
"toxcast-TOX21_p53_BLA_p5_viability": "bool",
"toxcast-Tanguay_ZF_120hpf_AXIS_up": "bool",
"toxcast-Tanguay_ZF_120hpf_ActivityScore": "bool",
"toxcast-Tanguay_ZF_120hpf_BRAI_up": "bool",
"toxcast-Tanguay_ZF_120hpf_CFIN_up": "bool",
"toxcast-Tanguay_ZF_120hpf_CIRC_up": "bool",
"toxcast-Tanguay_ZF_120hpf_EYE_up": "bool",
"toxcast-Tanguay_ZF_120hpf_JAW_up": "bool",
"toxcast-Tanguay_ZF_120hpf_MORT_up": "bool",
"toxcast-Tanguay_ZF_120hpf_OTIC_up": "bool",
"toxcast-Tanguay_ZF_120hpf_PE_up": "bool",
"toxcast-Tanguay_ZF_120hpf_PFIN_up": "bool",
"toxcast-Tanguay_ZF_120hpf_PIG_up": "bool",
"toxcast-Tanguay_ZF_120hpf_SNOU_up": "bool",
"toxcast-Tanguay_ZF_120hpf_SOMI_up": "bool",
"toxcast-Tanguay_ZF_120hpf_SWIM_up": "bool",
"toxcast-Tanguay_ZF_120hpf_TRUN_up": "bool",
"toxcast-Tanguay_ZF_120hpf_TR_up": "bool",
"toxcast-Tanguay_ZF_120hpf_YSE_up": "bool",
"clintox": "bool",
"herg": "bool",
"herg_central-hERG_at_1uM": "seq",
"herg_central-hERG_at_10uM": "seq",
"herg_central-hERG_inhib": "bool",
"dili": "bool",
"skin_reaction": "bool",
"ames": "bool",
"carcinogens_lagunin": "bool",
"ld50_zhu": "seq"
}
} |