Spaces:
Sleeping
Sleeping
File size: 12,374 Bytes
3ca1d38 696f787 3ca1d38 696f787 3ca1d38 9659593 3ca1d38 9659593 3ca1d38 696f787 3ca1d38 9659593 3ca1d38 9659593 3ca1d38 9659593 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 9659593 3ca1d38 9659593 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 9659593 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 9659593 3ca1d38 9659593 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 9659593 3ca1d38 9659593 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 9659593 696f787 3ca1d38 9659593 3ca1d38 9659593 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 696f787 3ca1d38 9659593 3ca1d38 | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 | """
MediGuard AI — Shared Utilities
Common functions used by both the main API and HuggingFace deployment:
- Biomarker parsing
- Disease scoring heuristics
- Result formatting
"""
from __future__ import annotations
import json
import logging
import re
from typing import Any
logger = logging.getLogger(__name__)
# ---------------------------------------------------------------------------
# Biomarker Parsing
# ---------------------------------------------------------------------------
# Canonical biomarker name mapping (aliases -> standard name)
BIOMARKER_ALIASES: dict[str, str] = {
# Glucose
"glucose": "Glucose",
"fasting glucose": "Glucose",
"fastingglucose": "Glucose",
"blood sugar": "Glucose",
"blood glucose": "Glucose",
"fbg": "Glucose",
"fbs": "Glucose",
# HbA1c
"hba1c": "HbA1c",
"a1c": "HbA1c",
"hemoglobin a1c": "HbA1c",
"hemoglobina1c": "HbA1c",
"glycated hemoglobin": "HbA1c",
# Cholesterol
"cholesterol": "Cholesterol",
"total cholesterol": "Cholesterol",
"totalcholesterol": "Cholesterol",
"tc": "Cholesterol",
# LDL
"ldl": "LDL",
"ldl cholesterol": "LDL",
"ldlcholesterol": "LDL",
"ldl-c": "LDL",
# HDL
"hdl": "HDL",
"hdl cholesterol": "HDL",
"hdlcholesterol": "HDL",
"hdl-c": "HDL",
# Triglycerides
"triglycerides": "Triglycerides",
"tg": "Triglycerides",
"trigs": "Triglycerides",
# Hemoglobin
"hemoglobin": "Hemoglobin",
"hgb": "Hemoglobin",
"hb": "Hemoglobin",
# TSH
"tsh": "TSH",
"thyroid stimulating hormone": "TSH",
# Creatinine
"creatinine": "Creatinine",
"cr": "Creatinine",
# ALT/AST
"alt": "ALT",
"sgpt": "ALT",
"ast": "AST",
"sgot": "AST",
# Blood pressure
"systolic": "Systolic_BP",
"systolic bp": "Systolic_BP",
"sbp": "Systolic_BP",
"diastolic": "Diastolic_BP",
"diastolic bp": "Diastolic_BP",
"dbp": "Diastolic_BP",
# BMI
"bmi": "BMI",
"body mass index": "BMI",
}
def normalize_biomarker_name(name: str) -> str:
"""
Normalize a biomarker name to its canonical form.
Args:
name: Raw biomarker name (may be alias, mixed case, etc.)
Returns:
Canonical biomarker name
"""
key = name.lower().strip().replace("_", " ")
return BIOMARKER_ALIASES.get(key, name)
def parse_biomarkers(text: str) -> dict[str, float]:
"""
Parse biomarkers from natural language text or JSON.
Supports formats like:
- JSON: {"Glucose": 140, "HbA1c": 7.5}
- Key-value: "Glucose: 140, HbA1c: 7.5"
- Natural: "glucose 140 mg/dL and hba1c 7.5%"
Args:
text: Input text containing biomarker values
Returns:
Dictionary of normalized biomarker names to float values
"""
text = text.strip()
if not text:
return {}
# Try JSON first
if text.startswith("{"):
try:
raw = json.loads(text)
return {normalize_biomarker_name(k): float(v) for k, v in raw.items()}
except (json.JSONDecodeError, ValueError, TypeError):
pass
# Regex patterns for biomarker extraction
patterns = [
# "Glucose: 140" or "Glucose = 140" or "Glucose - 140"
r"([A-Za-z][A-Za-z0-9_\s]{0,30})\s*[:=\-]\s*([\d.]+)",
# "Glucose 140 mg/dL" (value after name with optional unit)
r"\b([A-Za-z][A-Za-z0-9_]{0,15})\s+([\d.]+)\s*(?:mg/dL|mmol/L|%|g/dL|U/L|mIU/L|ng/mL|pg/mL|μmol/L|umol/L)?(?:\s|,|$)",
]
biomarkers: dict[str, float] = {}
for pattern in patterns:
for match in re.finditer(pattern, text, re.IGNORECASE):
name, value = match.groups()
name = name.strip()
# Skip common non-biomarker words
if name.lower() in {"the", "a", "an", "and", "or", "is", "was", "are", "were", "be"}:
continue
try:
fval = float(value)
canonical = normalize_biomarker_name(name)
# Don't overwrite if already found (first match wins)
if canonical not in biomarkers:
biomarkers[canonical] = fval
except ValueError:
continue
return biomarkers
# ---------------------------------------------------------------------------
# Disease Scoring Heuristics
# ---------------------------------------------------------------------------
# Reference ranges for biomarkers (approximate clinical ranges)
BIOMARKER_REFERENCE_RANGES: dict[str, tuple[float, float, str]] = {
# (low, high, unit)
"Glucose": (70, 100, "mg/dL"),
"HbA1c": (4.0, 5.6, "%"),
"Cholesterol": (0, 200, "mg/dL"),
"LDL": (0, 100, "mg/dL"),
"HDL": (40, 999, "mg/dL"), # Higher is better
"Triglycerides": (0, 150, "mg/dL"),
"Hemoglobin": (12.0, 17.5, "g/dL"),
"TSH": (0.4, 4.0, "mIU/L"),
"Creatinine": (0.6, 1.2, "mg/dL"),
"ALT": (7, 56, "U/L"),
"AST": (10, 40, "U/L"),
"Systolic_BP": (90, 120, "mmHg"),
"Diastolic_BP": (60, 80, "mmHg"),
"BMI": (18.5, 24.9, "kg/m²"),
}
def classify_biomarker(name: str, value: float) -> str:
"""
Classify a biomarker value as normal, low, or high.
Args:
name: Canonical biomarker name
value: Measured value
Returns:
"normal", "low", or "high"
"""
ranges = BIOMARKER_REFERENCE_RANGES.get(name)
if not ranges:
return "unknown"
low, high, _ = ranges
if value < low:
return "low"
elif value > high:
return "high"
else:
return "normal"
def score_disease_diabetes(biomarkers: dict[str, float]) -> tuple[float, str]:
"""
Score diabetes risk based on biomarkers.
Returns: (score 0-1, severity)
"""
glucose = biomarkers.get("Glucose", 0)
hba1c = biomarkers.get("HbA1c", 0)
score = 0.0
reasons = []
# HbA1c scoring (most important)
if hba1c >= 6.5:
score += 0.5
reasons.append(f"HbA1c {hba1c}% >= 6.5% (diabetes threshold)")
elif hba1c >= 5.7:
score += 0.3
reasons.append(f"HbA1c {hba1c}% in prediabetes range")
# Fasting glucose scoring
if glucose >= 126:
score += 0.35
reasons.append(f"Glucose {glucose} mg/dL >= 126 (diabetes threshold)")
elif glucose >= 100:
score += 0.2
reasons.append(f"Glucose {glucose} mg/dL in prediabetes range")
# Normalize to 0-1
score = min(1.0, score)
# Determine severity
if score >= 0.7:
severity = "high"
elif score >= 0.4:
severity = "moderate"
else:
severity = "low"
return score, severity
def score_disease_dyslipidemia(biomarkers: dict[str, float]) -> tuple[float, str]:
"""Score dyslipidemia risk based on lipid panel."""
cholesterol = biomarkers.get("Cholesterol", 0)
ldl = biomarkers.get("LDL", 0)
hdl = biomarkers.get("HDL", 999) # High default (higher is better)
triglycerides = biomarkers.get("Triglycerides", 0)
score = 0.0
if cholesterol >= 240:
score += 0.3
elif cholesterol >= 200:
score += 0.15
if ldl >= 160:
score += 0.3
elif ldl >= 130:
score += 0.15
if hdl < 40:
score += 0.2
if triglycerides >= 200:
score += 0.2
elif triglycerides >= 150:
score += 0.1
score = min(1.0, score)
if score >= 0.6:
severity = "high"
elif score >= 0.3:
severity = "moderate"
else:
severity = "low"
return score, severity
def score_disease_anemia(biomarkers: dict[str, float]) -> tuple[float, str]:
"""Score anemia risk based on hemoglobin."""
hemoglobin = biomarkers.get("Hemoglobin", 0)
if not hemoglobin:
return 0.0, "unknown"
if hemoglobin < 8:
return 0.9, "critical"
elif hemoglobin < 10:
return 0.7, "high"
elif hemoglobin < 12:
return 0.5, "moderate"
elif hemoglobin < 13:
return 0.2, "low"
else:
return 0.0, "normal"
def score_disease_thyroid(biomarkers: dict[str, float]) -> tuple[float, str, str]:
"""Score thyroid disorder risk. Returns: (score, severity, direction)."""
tsh = biomarkers.get("TSH", 0)
if not tsh:
return 0.0, "unknown", "none"
if tsh > 10:
return 0.8, "high", "hypothyroid"
elif tsh > 4.5:
return 0.5, "moderate", "hypothyroid"
elif tsh < 0.1:
return 0.8, "high", "hyperthyroid"
elif tsh < 0.4:
return 0.5, "moderate", "hyperthyroid"
else:
return 0.0, "normal", "none"
def score_all_diseases(biomarkers: dict[str, float]) -> dict[str, dict[str, Any]]:
"""
Score all disease risks based on available biomarkers.
Args:
biomarkers: Dictionary of biomarker values
Returns:
Dictionary of disease -> {score, severity, disease, confidence}
"""
results = {}
# Diabetes
score, severity = score_disease_diabetes(biomarkers)
if score > 0:
results["diabetes"] = {
"disease": "Diabetes",
"confidence": score,
"severity": severity,
}
# Dyslipidemia
score, severity = score_disease_dyslipidemia(biomarkers)
if score > 0:
results["dyslipidemia"] = {
"disease": "Dyslipidemia",
"confidence": score,
"severity": severity,
}
# Anemia
score, severity = score_disease_anemia(biomarkers)
if score > 0:
results["anemia"] = {
"disease": "Anemia",
"confidence": score,
"severity": severity,
}
# Thyroid
score, severity, direction = score_disease_thyroid(biomarkers)
if score > 0:
disease_name = "Hypothyroidism" if direction == "hypothyroid" else "Hyperthyroidism"
results["thyroid"] = {
"disease": disease_name,
"confidence": score,
"severity": severity,
}
return results
def get_primary_prediction(biomarkers: dict[str, float]) -> dict[str, Any]:
"""
Get the highest-confidence disease prediction.
Args:
biomarkers: Dictionary of biomarker values
Returns:
Dictionary with disease, confidence, severity
"""
scores = score_all_diseases(biomarkers)
if not scores:
return {
"disease": "General Health Screening",
"confidence": 0.5,
"severity": "low",
}
# Return highest confidence
best = max(scores.values(), key=lambda x: x["confidence"])
return best
# ---------------------------------------------------------------------------
# Biomarker Flagging
# ---------------------------------------------------------------------------
def flag_biomarkers(biomarkers: dict[str, float]) -> list[dict[str, Any]]:
"""
Flag abnormal biomarkers with classification and reference ranges.
Args:
biomarkers: Dictionary of biomarker values
Returns:
List of flagged biomarkers with details
"""
flags = []
for name, value in biomarkers.items():
classification = classify_biomarker(name, value)
ranges = BIOMARKER_REFERENCE_RANGES.get(name)
flag = {
"name": name,
"value": value,
"status": classification,
}
if ranges:
low, high, unit = ranges
flag["reference_range"] = f"{low}-{high} {unit}"
flag["unit"] = unit
if classification != "normal":
flag["flagged"] = True
flags.append(flag)
# Sort: flagged first, then by name
flags.sort(key=lambda x: (not x.get("flagged", False), x["name"]))
return flags
# ---------------------------------------------------------------------------
# Utility Functions
# ---------------------------------------------------------------------------
def format_confidence_percent(score: float) -> str:
"""Format confidence score as percentage string."""
return f"{int(score * 100)}%"
def severity_to_emoji(severity: str) -> str:
"""Convert severity level to emoji."""
mapping = {
"critical": "🔴",
"high": "🟠",
"moderate": "🟡",
"low": "🟢",
"normal": "✅",
"unknown": "❓",
}
return mapping.get(severity.lower(), "⚪")
|