"""
MediGuard AI RAG-Helper
Main LangGraph Workflow - Clinical Insight Guild Orchestration
"""

from langgraph.graph import END, StateGraph

from src.pdf_processor import get_all_retrievers
from src.state import GuildState


class ClinicalInsightGuild:
    """
    Main workflow orchestrator for MediGuard AI RAG-Helper.
    Coordinates all specialist agents in the Clinical Insight Guild.
    """

    def __init__(self):
        """Initialize the guild with all specialist agents"""
        print("\n" + "=" * 70)
        print("INITIALIZING: Clinical Insight Guild")
        print("=" * 70)

        # Load retrievers
        print("\nLoading RAG retrievers...")
        retrievers = get_all_retrievers()

        # Import and initialize all agents
        from src.agents.biomarker_analyzer import biomarker_analyzer_agent
        from src.agents.biomarker_linker import create_biomarker_linker_agent
        from src.agents.clinical_guidelines import create_clinical_guidelines_agent
        from src.agents.confidence_assessor import confidence_assessor_agent
        from src.agents.disease_explainer import create_disease_explainer_agent
        from src.agents.response_synthesizer import response_synthesizer_agent

        self.biomarker_analyzer = biomarker_analyzer_agent
        self.disease_explainer = create_disease_explainer_agent(retrievers["disease_explainer"])
        self.biomarker_linker = create_biomarker_linker_agent(retrievers["biomarker_linker"])
        self.clinical_guidelines = create_clinical_guidelines_agent(retrievers["clinical_guidelines"])
        self.confidence_assessor = confidence_assessor_agent
        self.response_synthesizer = response_synthesizer_agent

        print("All agents initialized successfully")

        # Build workflow graph
        self.workflow = self._build_workflow()
        print("Workflow graph compiled")
        print("=" * 70 + "\n")

    def _build_workflow(self):
        """
        Build the LangGraph workflow.

        Execution flow:
        1. Biomarker Analyzer (validates all biomarkers)
        2. Parallel execution:
           - Disease Explainer (RAG for pathophysiology)
           - Biomarker-Disease Linker (connects values to prediction)
           - Clinical Guidelines (RAG for recommendations)
        3. Confidence Assessor (evaluates reliability)
        4. Response Synthesizer (compiles final output)
        """

        # Create state graph
        workflow = StateGraph(GuildState)

        # Add all agent nodes
        workflow.add_node("biomarker_analyzer", self.biomarker_analyzer.analyze)
        workflow.add_node("disease_explainer", self.disease_explainer.explain)
        workflow.add_node("biomarker_linker", self.biomarker_linker.link)
        workflow.add_node("clinical_guidelines", self.clinical_guidelines.recommend)
        workflow.add_node("confidence_assessor", self.confidence_assessor.assess)
        workflow.add_node("response_synthesizer", self.response_synthesizer.synthesize)

        # Define execution flow
        # Start -> Biomarker Analyzer
        workflow.set_entry_point("biomarker_analyzer")

        # Biomarker Analyzer -> Parallel specialists
        workflow.add_edge("biomarker_analyzer", "disease_explainer")
        workflow.add_edge("biomarker_analyzer", "biomarker_linker")
        workflow.add_edge("biomarker_analyzer", "clinical_guidelines")

        # All parallel specialists -> Confidence Assessor
        workflow.add_edge("disease_explainer", "confidence_assessor")
        workflow.add_edge("biomarker_linker", "confidence_assessor")
        workflow.add_edge("clinical_guidelines", "confidence_assessor")

        # Confidence Assessor -> Response Synthesizer
        workflow.add_edge("confidence_assessor", "response_synthesizer")

        # Response Synthesizer -> END
        workflow.add_edge("response_synthesizer", END)

        # Compile workflow (returns CompiledGraph with invoke method)
        return workflow.compile()

    def run(self, patient_input) -> dict:
        """
        Execute the complete Clinical Insight Guild workflow.

        Args:
            patient_input: PatientInput object with biomarkers and ML prediction

        Returns:
            Complete structured response dictionary
        """
        from datetime import datetime

        from src.config import BASELINE_SOP

        print("\n" + "=" * 70)
        print("STARTING: Clinical Insight Guild Workflow")
        print("=" * 70)
        print(f"Patient: {patient_input.patient_context.get('patient_id', 'Unknown')}")
        print(f"Predicted Disease: {patient_input.model_prediction['disease']}")
        print(f"Model Confidence: {patient_input.model_prediction['confidence']:.1%}")
        print("=" * 70 + "\n")

        # Initialize state from PatientInput
        initial_state: GuildState = {
            "patient_biomarkers": patient_input.biomarkers,
            "model_prediction": patient_input.model_prediction,
            "patient_context": patient_input.patient_context,
            "plan": None,
            "sop": BASELINE_SOP,
            "agent_outputs": [],
            "biomarker_flags": [],
            "safety_alerts": [],
            "final_response": None,
            "biomarker_analysis": None,
            "processing_timestamp": datetime.now().isoformat(),
            "sop_version": "Baseline",
        }

        # Run workflow
        final_state = self.workflow.invoke(initial_state)

        print("\n" + "=" * 70)
        print("COMPLETED: Clinical Insight Guild Workflow")
        print("=" * 70)
        print(f"Total Agents Executed: {len(final_state.get('agent_outputs', []))}")
        print("Workflow execution successful")
        print("=" * 70 + "\n")

        # Return full state so callers can access agent_outputs,
        # biomarker_flags, safety_alerts, and final_response
        return dict(final_state)


def create_guild() -> ClinicalInsightGuild:
    """Factory function to create and initialize the Clinical Insight Guild"""
    return ClinicalInsightGuild()


if __name__ == "__main__":
    # Test workflow initialization
    print("Testing Clinical Insight Guild initialization...")
    guild = create_guild()
    print("\nGuild initialization successful!")
    print("Ready to process patient inputs.")