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API interface for HeartMAP
"""
from typing import Dict, Any, Optional, Union, List
import warnings
from pathlib import Path
import tempfile
from ..config import Config, load_config
try:
from fastapi import FastAPI, UploadFile, File, HTTPException
from pydantic import BaseModel as PydanticBaseModel
import uvicorn
FASTAPI_AVAILABLE = True
except ImportError:
FASTAPI_AVAILABLE = False
warnings.warn("FastAPI not available. Install with: pip install fastapi uvicorn")
# Create a dummy BaseModel for when FastAPI/Pydantic is not available
class PydanticBaseModel: # type: ignore
def __init__(self, **kwargs):
for key, value in kwargs.items():
setattr(self, key, value)
from ..pipelines import (
BasicPipeline,
AdvancedCommunicationPipeline,
MultiChamberPipeline,
ComprehensivePipeline
)
class AnalysisRequest(PydanticBaseModel):
"""Request model for analysis"""
analysis_type: str = "comprehensive" # basic, advanced, multi_chamber, comprehensive
config_overrides: Optional[Dict[str, Any]] = None
output_format: str = "json" # json, csv, h5ad
class AnalysisResponse(PydanticBaseModel):
"""Response model for analysis"""
status: str
message: str
results: Optional[Dict[str, Any]] = None
output_files: Optional[List[str]] = None
class HeartMapAPI:
"""REST API for HeartMAP analysis"""
def __init__(self, config: Union[str, Config, None] = None):
if isinstance(config, Config):
self.config = config
else:
self.config = load_config(config)
self.app = FastAPI(
title="HeartMAP API",
description="Heart Multi-chamber Analysis Platform API",
version="1.0.0"
) if FASTAPI_AVAILABLE else None
if FASTAPI_AVAILABLE:
self._setup_routes()
def _setup_routes(self):
"""Setup API routes"""
@self.app.get("/")
async def root():
return {"message": "HeartMAP API", "version": "1.0.0"}
@self.app.get("/health")
async def health_check():
return {"status": "healthy"}
@self.app.post("/analyze", response_model=AnalysisResponse)
async def analyze_data(
file: UploadFile = File(...),
request: AnalysisRequest = AnalysisRequest()
):
"""Analyze single-cell data"""
try:
# Save uploaded file temporarily
with tempfile.NamedTemporaryFile(delete=False, suffix=".h5ad") as tmp_file:
content = await file.read()
tmp_file.write(content)
tmp_file_path = tmp_file.name
# Update config with overrides
if request.config_overrides:
# Apply config overrides (simplified)
pass
# Create output directory
with tempfile.TemporaryDirectory() as output_dir:
# Run analysis based on type
pipeline = self._get_pipeline(request.analysis_type)
results = pipeline.run(tmp_file_path, output_dir)
# Format response
response_data = self._format_results(results, request.output_format)
return AnalysisResponse(
status="success",
message="Analysis completed successfully",
results=response_data
)
except Exception as e:
raise HTTPException(status_code=500, detail=str(e))
finally:
# Clean up temporary file
Path(tmp_file_path).unlink(missing_ok=True)
@self.app.get("/models")
async def list_models():
"""List available analysis models"""
return {
"models": [
"basic",
"advanced_communication",
"multi_chamber",
"comprehensive"
]
}
@self.app.get("/config")
async def get_config():
"""Get current configuration"""
return self.config.to_dict()
@self.app.post("/config")
async def update_config(new_config: Dict[str, Any]):
"""Update configuration"""
try:
self.config = Config.from_dict(new_config)
return {"status": "success", "message": "Configuration updated"}
except Exception as e:
raise HTTPException(status_code=400, detail=str(e))
def _get_pipeline(self, analysis_type: str):
"""Get analysis pipeline by type"""
pipelines = {
"basic": BasicPipeline(self.config),
"advanced_communication": AdvancedCommunicationPipeline(self.config),
"multi_chamber": MultiChamberPipeline(self.config),
"comprehensive": ComprehensivePipeline(self.config)
}
if analysis_type not in pipelines:
raise ValueError(f"Unknown analysis type: {analysis_type}")
return pipelines[analysis_type]
def _format_results(self, results: Dict[str, Any], output_format: str) -> Dict[str, Any]:
"""Format results for API response"""
if output_format == "json":
# Convert complex objects to serializable format
formatted = {}
if 'results' in results:
res = results['results']
formatted['summary'] = {
'n_cells': results.get('adata', {}).n_obs if 'adata' in results else 0,
'analysis_completed': True
}
# Extract key metrics
if 'annotation' in res:
ann_res = res['annotation']
if 'metadata' in ann_res:
formatted['annotation_summary'] = ann_res['metadata']
if 'communication' in res:
comm_res = res['communication']
if 'metadata' in comm_res:
formatted['communication_summary'] = comm_res['metadata']
if 'multi_chamber' in res:
chamber_res = res['multi_chamber']
if 'metadata' in chamber_res:
formatted['multi_chamber_summary'] = chamber_res['metadata']
return formatted
else:
raise ValueError(f"Unsupported output format: {output_format}")
def run(self, host: str = "0.0.0.0", port: int = 8000, debug: bool = False):
"""Run the API server"""
if not FASTAPI_AVAILABLE:
raise ImportError("FastAPI not available. Install with: pip install fastapi uvicorn")
if self.app is not None:
uvicorn.run(self.app, host=host, port=port, log_level="debug" if debug else "info")
class CLIInterface:
"""Command line interface for HeartMAP"""
def __init__(self):
self.config = None
def run_analysis(self,
data_path: str,
analysis_type: str = "comprehensive",
output_dir: str = "results",
config_path: Optional[str] = None):
"""Run analysis from command line"""
# Load configuration
self.config = load_config(config_path)
# Update output directory
self.config.update_paths(str(Path(output_dir).parent))
self.config.create_directories()
# Get pipeline
pipelines = {
"basic": BasicPipeline(self.config),
"advanced": AdvancedCommunicationPipeline(self.config),
"multi_chamber": MultiChamberPipeline(self.config),
"comprehensive": ComprehensivePipeline(self.config)
}
if analysis_type not in pipelines:
raise ValueError(f"Unknown analysis type: {analysis_type}")
pipeline = pipelines[analysis_type]
# Run analysis
print(f"Starting {analysis_type} analysis...")
results = pipeline.run(data_path, output_dir)
print(f"Analysis completed! Results saved to: {output_dir}")
return results
def create_api(config_path: Optional[str] = None) -> HeartMapAPI:
"""Create HeartMAP API instance"""
return HeartMapAPI(config_path)
def run_cli():
"""Run command line interface"""
import argparse
parser = argparse.ArgumentParser(description="HeartMAP Analysis Platform")
parser.add_argument("data_path", help="Path to input data file")
parser.add_argument("--analysis-type", default="comprehensive",
choices=["basic", "advanced", "multi_chamber", "comprehensive"],
help="Type of analysis to run")
parser.add_argument("--output-dir", default="results",
help="Output directory for results")
parser.add_argument("--config", help="Path to configuration file")
args = parser.parse_args()
cli = CLIInterface()
cli.run_analysis(
data_path=args.data_path,
analysis_type=args.analysis_type,
output_dir=args.output_dir,
config_path=args.config
)
# Export API classes and functions
__all__ = [
'AnalysisRequest',
'AnalysisResponse',
'HeartMapAPI',
'CLIInterface',
'create_api',
'run_cli'
]
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