Remove test cache artifacts

Implement complete API contract, persistence, jobs, artifacts, and architecture status

Remove legacy application files

Fix all sidebar filters and add live Rescue score reweighting

Physics-based scoring: NP_000537.3 QC, literature dDG, RT ln Kd, Lipinski/QED, Rescue formula, real-world ingest

Deploy TP53 discovery dashboard with datasets and interactive figures

initial commit