guias/bacteremia_cateter.html

<div id="corta_sin_candida" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
  <h2 class="text-base font-bold text-gray-800 mb-4 flex items-center gap-2"><i class="fas fa-vial text-red-500 fa-fw"></i> Corta duración sin riesgo de Cándida</h2>

  <div class="mb-4">
    <h3 class="text-base font-semibold text-gray-700 mb-2 flex items-center gap-2"><i class="fas fa-bug text-blue-500 fa-fw"></i> Etiología frecuente</h3>
    <div class="pathogen-list flex flex-wrap gap-2 my-2">
      <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">S. epidermidis</span>
      <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">Coagulasa-negativos</span>
      <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
      <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">Enterococcus spp.</span>
      <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">Enterobacterias</span>
      <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">P. aeruginosa</span>
    </div>
  </div>

  <div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
    <div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> Tratamiento de elección</div>
    <p class="text-base text-gray-700">Vancomicina 15 mg/kg IV cada 12 h* + Ceftazidima 2 g IV cada 8 h <strong>o</strong> Piperacilina-Tazobactam 4,5 g IV cada 6 h.</p>
  </div>

  <div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
    <div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-exchange-alt text-blue-500 fa-fw"></i> Alternativa (alergia BL)</div>
    <p class="text-base text-gray-700">Vancomicina 15 mg/kg IV cada 12 h* + Aztreonam 2 g IV cada 8 h <strong>o</strong> Amikacina 20 mg/kg/día IV.</p>
  </div>

  <div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 my-3 rounded-r-lg">
    <div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-amber-500 fa-fw"></i> Observaciones</div>
    <ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
      <li>Extraer hemocultivos de todas las luces y de vena periférica.</li>
      <li>Retirar catéter periférico siempre; central si no necesario o complicaciones.</li>
      <li>Tratamiento en domicilio posible con mismas pautas.</li>
      <li>*Solicitar niveles de vancomicina desde tercera dosis.</li>
    </ul>
  </div>
</div>

<div id="corta_con_candida" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
  <h2 class="text-base font-bold text-gray-800 mb-4 flex items-center gap-2"><i class="fas fa-vial text-red-500 fa-fw"></i> Corta duración con riesgo de Cándida</h2>
  <div class="mb-4">
    <h3 class="text-base font-semibold text-gray-700 mb-2 flex items-center gap-2"><i class="fas fa-bug text-blue-500 fa-fw"></i> Etiología frecuente</h3>
    <div class="pathogen-list flex flex-wrap gap-2 my-2">
      <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">(Previas)</span>
      <span class="pathogen-item bg-pink-100 text-pink-700 px-3 py-1 rounded-full text-sm font-medium">+ Cándida spp.</span>
    </div>
  </div>
  <div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-purple-600">
    <div class="treatment-title text-base font-semibold text-purple-800 mb-1.5 flex items-center gap-2"><i class="fas fa-star text-purple-500 fa-fw"></i> Shock o riesgo elevado</div>
    <p class="text-base text-gray-700">Anidulafungina 200 mg IV primer día, luego 100 mg IV/24 h + pauta antibacteriana estándar (Vancomicina + Ceftazidima o Piperacilina-Tazobactam).</p>
  </div>
  <div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-purple-600">
    <div class="treatment-title text-base font-semibold text-purple-800 mb-1.5 flex items-center gap-2"><i class="fas fa-star text-purple-500 fa-fw"></i> Resto de casos</div>
    <p class="text-base text-gray-700">Fluconazol 800 mg IV en dosis de carga, luego 400 mg IV/24 h + antibacteriana estándar.</p>
  </div>
  <div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 my-3 rounded-r-lg">
    <div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-exclamation-circle text-amber-500 fa-fw"></i> Factores de riesgo Candida</div>
    <ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
      <li>Sepsis grave o shock</li>
      <li>Nutrición parenteral, cirugía abdominal, pancreatitis</li>
      <li>Neoplasias, neutropenia, trasplantes</li>
      <li>Colonización previa, sondas femorales, UCI</li>
    </ul>
  </div>
</div>

<div id="larga_sin_candida" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
  <h2 class="text-base font-bold text-gray-800 mb-4 flex items-center gap-2"><i class="fas fa-lock text-blue-500 fa-fw"></i> Larga duración sin riesgo de Cándida</h2>
  <div class="mb-4">
      <h3 class="text-base font-semibold text-gray-700 mb-2 flex items-center gap-2"><i class="fas fa-bug text-blue-500 fa-fw"></i> Etiología frecuente</h3>
      <div class="pathogen-list flex flex-wrap gap-2 my-2">
          <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">S. epidermidis</span>
          <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
          <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">Enterococcus spp.</span>
          <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">Enterobacterias</span>
          <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">P. aeruginosa</span>
      </div>
  </div>
  <div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
    <div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> Tratamiento de elección</div>
    <p class="text-base text-gray-700">Vancomicina 15 mg/kg IV c/12 h* + Ceftazidima 2 g IV c/8 h <strong>o</strong> Piperacilina-Tazobactam 4,5 g IV c/6 h.</p>
  </div>
  <div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
    <div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-exchange-alt text-blue-500 fa-fw"></i> Alternativa (alergia BL)</div>
    <p class="text-base text-gray-700">Vancomicina 15 mg/kg IV c/12 h* + Aztreonam 2 g IV c/8 h <strong>o</strong> Amikacina 20 mg/kg/día IV.</p>
  </div>
  <div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 my-3 rounded-r-lg">
    <div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-yellow-500 fa-fw"></i> Observaciones</div>
    <ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
      <li>Considerar sellado de catéter si no se retira.</li>
      <li>Hemocultivos de control cada 72 h hasta negativizar.</li>
      <li>Retirar si persiste bacteriemia >72 h.</li>
    </ul>
  </div>
</div>

<div id="larga_con_candida" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
  <h2 class="text-base font-bold text-gray-800 mb-4 flex items-center gap-2"><i class="fas fa-lock text-blue-500 fa-fw"></i> Larga duración con riesgo de Cándida</h2>
   <div class="mb-4">
     <h3 class="text-base font-semibold text-gray-700 mb-2 flex items-center gap-2"><i class="fas fa-bug text-blue-500 fa-fw"></i> Etiología frecuente</h3>
     <div class="pathogen-list flex flex-wrap gap-2 my-2">
         <span class="pathogen-item bg-sky-100 text-sky-700 px-3 py-1 rounded-full text-sm font-medium">(Previas)</span>
         <span class="pathogen-item bg-pink-100 text-pink-700 px-3 py-1 rounded-full text-sm font-medium">+ Cándida spp.</span>
     </div>
   </div>
  <div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-purple-600">
    <div class="treatment-title text-base font-semibold text-purple-800 mb-1.5 flex items-center gap-2"><i class="fas fa-star text-purple-500 fa-fw"></i> Shock o riesgo elevado</div>
    <p class="text-base text-gray-700">Anidulafungina 200 mg IV primer día, luego 100 mg IV/24 h + antibacteriana estándar.</p>
  </div>
  <div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-purple-600">
    <div class="treatment-title text-base font-semibold text-purple-800 mb-1.5 flex items-center gap-2"><i class="fas fa-star text-purple-500 fa-fw"></i> Resto de casos</div>
    <p class="text-base text-gray-700">Fluconazol 800 mg IV dosis de carga, luego 400 mg IV/24 h + antibacteriana estándar.</p>
  </div>
   </div>