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<div id="esofagitis" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-4 flex items-center gap-2"><i class="fas fa-notes-medical text-red-500 fa-fw"></i> Esofagitis infecciosa</h2>
<h3 class="text-base font-semibold text-gray-700 mt-4 mb-2 flex items-center gap-2"><i class="fas fa- грибок text-orange-500 fa-fw"></i> Fúngica (Candidiasis)</h3> <div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> De elección</div>
<p class="text-base text-gray-700">Fluconazol 40 mg dosis única, seguido de 200-400 mg/24 h VO.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-exchange-alt text-blue-500 fa-fw"></i> Alternativa</div>
<p class="text-base text-gray-700">Voriconazol 200 mg/12 h VO.</p>
</div>
<h3 class="text-base font-semibold text-gray-700 mt-5 mb-2 flex items-center gap-2"><i class="fas fa-virus text-purple-500 fa-fw"></i> Vírica (inmunodeprimidos)</h3>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-indigo-600">
<div class="treatment-title text-base font-semibold text-indigo-800 mb-1.5 flex items-center gap-2"><i class="fas fa-shield-virus text-indigo-500 fa-fw"></i> VHS</div>
<p class="text-base text-gray-700">Aciclovir 5-10 mg/kg/8 h IV o 400 mg 5 × día VO.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-indigo-600">
<div class="treatment-title text-base font-semibold text-indigo-800 mb-1.5 flex items-center gap-2"><i class="fas fa-shield-virus text-indigo-500 fa-fw"></i> CMV</div>
<p class="text-base text-gray-700">Ganciclovir 5 mg/kg/12 h IV → Valganciclovir 900 mg/24 h VO.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-5 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-amber-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Duración: Candida/VHS 14–21 días; CMV 21–28 días.</li>
<li>Si no responde, endoscopia y biopsia.</li>
</ul>
</div>
</div>
<div id="gastroenteritis" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-4 flex items-center gap-2"><i class="fas fa-stomach text-yellow-600 fa-fw"></i> Gastroenteritis aguda</h2>
<h3 class="text-base font-semibold text-gray-700 mt-4 mb-2 flex items-center gap-2"><i class="fas fa-water text-blue-400 fa-fw"></i> No inflamatoria</h3>
<div class="note-box bg-blue-50 border-l-4 border-blue-400 p-3 my-3 rounded-r-lg"> <div class="note-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-prescription-bottle-alt text-blue-500 fa-fw"></i> Manejo</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Tratamiento sintomático: dieta, evitar lácteos.</li>
<li>Estudios: coprocultivo y detección viral.</li>
</ul>
</div>
<h3 class="text-base font-semibold text-gray-700 mt-5 mb-2 flex items-center gap-2"><i class="fas fa-fire text-red-500 fa-fw"></i> Inflamatoria</h3>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-red-100 text-red-700 px-3 py-1 rounded-full text-sm font-medium">Campylobacter</span>
<span class="pathogen-item bg-red-100 text-red-700 px-3 py-1 rounded-full text-sm font-medium">Salmonella</span>
<span class="pathogen-item bg-red-100 text-red-700 px-3 py-1 rounded-full text-sm font-medium">Shigella</span>
<span class="pathogen-item bg-red-100 text-red-700 px-3 py-1 rounded-full text-sm font-medium">E. coli ent.</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-green-600">
<div class="treatment-title text-base font-semibold text-green-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> De elección</div>
<p class="text-base text-gray-700">Azitromicina 500 mg/24 h IV/VO 3–5 días.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-green-600">
<div class="treatment-title text-base font-semibold text-green-800 mb-1.5 flex items-center gap-2"><i class="fas fa-exchange-alt text-blue-500 fa-fw"></i> Alternativa</div>
<p class="text-base text-gray-700">Ciprofloxacino 500 mg/12 h IV 5–7 días.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-5 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-amber-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Solo antibiótico si: diarrea sanguinolenta, SRIS, >65 años, inmunodeprimidos, viajero grave.</li>
</ul>
</div>
</div>
<div id="colitis_cd" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-4 flex items-center gap-2"><i class="fas fa-bacteria text-purple-500 fa-fw"></i> Colitis por C. difficile</h2>
<h3 class="text-base font-semibold text-gray-700 mt-4 mb-2 flex items-center gap-2"><i class="fas fa-thermometer-quarter text-green-500 fa-fw"></i> Primer episodio leve</h3>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-teal-600">
<div class="treatment-title text-base font-semibold text-teal-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> De elección</div>
<p class="text-base text-gray-700">Vancomicina 125 mg/6 h VO 10 días.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-teal-600">
<div class="treatment-title text-base font-semibold text-teal-800 mb-1.5 flex items-center gap-2"><i class="fas fa-exchange-alt text-blue-500 fa-fw"></i> Alternativa</div>
<p class="text-base text-gray-700">Metronidazol 500 mg/8 h VO 10 días.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-teal-600">
<div class="treatment-title text-base font-semibold text-teal-800 mb-1.5 flex items-center gap-2"><i class="fas fa-capsules text-orange-500 fa-fw"></i> Fidaxomicina</div>
<p class="text-base text-gray-700">200 mg/12 h VO 10 días (vulnerable/recurrencia).</p>
</div>
<h3 class="text-base font-semibold text-gray-700 mt-5 mb-2 flex items-center gap-2"><i class="fas fa-redo text-orange-600 fa-fw"></i> Episodios recurrencias</h3>
<div class="note-box bg-orange-50 border-l-4 border-orange-500 p-3 my-3 rounded-r-lg"> <div class="note-title text-base font-semibold text-orange-800 mb-1.5 flex items-center gap-2"><i class="fas fa-book-medical text-orange-600 fa-fw"></i> Ver protocolos de recidiva</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Pauta descendente de vancomicina o fidaxomicina ± bezlotoxumab.</li>
<li>Fecal microbiota transplant si ≥3 recidivas.</li>
</ul>
</div>
</div>
<div id="colangitis" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-4 flex items-center gap-2"><i class="fas fa-icicles text-cyan-500 fa-fw"></i> Colangitis</h2> <h3 class="text-base font-semibold text-gray-700 mt-4 mb-2 flex items-center gap-2"><i class="fas fa-thermometer-half text-yellow-500 fa-fw"></i> Leve-moderada</h3>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-cyan-100 text-cyan-700 px-3 py-1 rounded-full text-sm font-medium">E. coli</span>
<span class="pathogen-item bg-cyan-100 text-cyan-700 px-3 py-1 rounded-full text-sm font-medium">Enterobacterias</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-cyan-600">
<div class="treatment-title text-base font-semibold text-cyan-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> De elección</div>
<p class="text-base text-gray-700">Ceftriaxona 1–2 g/24 h IV o cefotaxima 2 g/8 h IV.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-cyan-600">
<div class="treatment-title text-base font-semibold text-cyan-800 mb-1.5 flex items-center gap-2"><i class="fas fa-shield-alt text-orange-500 fa-fw"></i> Alternativa (BLEE)</div>
<p class="text-base text-gray-700">Ertapenem 1 g/24 h IV.</p>
</div>
<h3 class="text-base font-semibold text-gray-700 mt-5 mb-2 flex items-center gap-2"><i class="fas fa-thermometer-full text-red-500 fa-fw"></i> Grave</h3>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-red-600">
<div class="treatment-title text-base font-semibold text-red-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> De elección</div>
<p class="text-base text-gray-700">Meropenem 1 g/8 h o Piperacilina/Tazobactam 4,5 g/6 h IV.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-5 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-amber-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Drenaje biliar precoz (CPRE <48–72 h).</li>
<li>Duración según evolución; suspender tras 72 h afebril.</li>
</ul>
</div>
</div>
<div id="colecistitis_simple" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-4 flex items-center gap-2"><i class="fas fa-dot-circle text-yellow-500 fa-fw"></i> Colecistitis aguda simple</h2> <div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">E. coli</span>
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">Enterobacterias</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-yellow-600">
<div class="treatment-title text-base font-semibold text-yellow-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> De elección</div>
<p class="text-base text-gray-700">Cefotaxima 1–2 g/8 h IV o ceftriaxona 1–2 g/24 h IV.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-yellow-600">
<div class="treatment-title text-base font-semibold text-yellow-800 mb-1.5 flex items-center gap-2"><i class="fas fa-exchange-alt text-blue-500 fa-fw"></i> Alternativa</div>
<p class="text-base text-gray-700">Aztreonam 1–2 g/8 h IV o Amikacina 15 mg/kg/día IV.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-amber-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Colecistectomía precoz (48–72 h).</li>
<li>Duración ATB: 72 h post-colecistectomía o 7–10 días.</li>
</ul>
</div>
</div>
<div id="colecistitis_comp" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-4 flex items-center gap-2"><i class="fas fa-exclamation-triangle text-red-600 fa-fw"></i> Colecistitis complicada</h2> <div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-red-100 text-red-700 px-3 py-1 rounded-full text-sm font-medium">Enterobacterias</span>
<span class="pathogen-item bg-red-100 text-red-700 px-3 py-1 rounded-full text-sm font-medium">Enterococcus</span>
<span class="pathogen-item bg-red-100 text-red-700 px-3 py-1 rounded-full text-sm font-medium">P. aeruginosa</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-red-600">
<div class="treatment-title text-base font-semibold text-red-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> De elección</div>
<p class="text-base text-gray-700">Piperacilina/Tazobactam 4 g/6 h IV ± Meropenem 1–2 g/8 h si sepsis.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-amber-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Colecistectomía urgente si absceso o gangrena.</li>
<li>Duración: 14 días IV.</li>
</ul>
</div>
</div>
<div id="peritonitis" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-4 flex items-center gap-2"><i class="fas fa-water text-teal-500 fa-fw"></i> Peritonitis bacteriana espontánea</h2> <h3 class="text-base font-semibold text-gray-700 mt-4 mb-2 flex items-center gap-2"><i class="fas fa-hospital text-blue-500 fa-fw"></i> Comunitaria</h3>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-blue-100 text-blue-700 px-3 py-1 rounded-full text-sm font-medium">E. coli</span>
<span class="pathogen-item bg-blue-100 text-blue-700 px-3 py-1 rounded-full text-sm font-medium">Klebsiella</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> De elección</div>
<p class="text-base text-gray-700">Ceftriaxona 2 g/24 h IV o cefotaxima 2 g/8 h IV.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-exchange-alt text-blue-500 fa-fw"></i> Alternativa</div>
<p class="text-base text-gray-700">Levofloxacino 750 mg/24 h IV o Aztreonam 2 g/8 h IV.</p>
</div>
<h3 class="text-base font-semibold text-gray-700 mt-5 mb-2 flex items-center gap-2"><i class="fas fa-clinic-medical text-red-500 fa-fw"></i> Nosocomial o con riesgo</h3>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-red-600">
<div class="treatment-title text-base font-semibold text-red-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> De elección</div>
<p class="text-base text-gray-700">Piperacilina/Tazobactam 4 g/8 h IV ± Linezolid 600 mg/12 h IV.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-5 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-amber-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Duración: 5–7 días (ajustar).</li>
<li>Paracentesis diagnóstica y cultivos.</li>
<li>Albúmina profiláctica en cirróticos.</li>
</ul>
</div>
</div>