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<div id="bursitis" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-joint text-blue-800 fa-fw"></i> Bursitis Infecciosa</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
<span class="pathogen-item bg-red-100 text-red-700 px-3 py-1 rounded-full text-sm font-medium">Estreptococos</span>
<span class="pathogen-item bg-cyan-100 text-cyan-700 px-3 py-1 rounded-full text-sm font-medium">Bacilos G(-)</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-clinic-medical text-green-500 fa-fw"></i> Sin ingreso</div>
<p class="text-base text-gray-700">Cefadroxilo 1 g VO c/12 h. Si SARM: Linezolid 600 mg VO c/12 h.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-red-600">
<div class="treatment-title text-base font-semibold text-red-800 mb-1.5 flex items-center gap-2"><i class="fas fa-hospital text-red-500 fa-fw"></i> Con ingreso</div>
<p class="text-base text-gray-700">Cefazolina 2 g IV c/8 h. Si SARM: Daptomicina 8-10 mg/kg IV/24 h.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Duración 7-14 días según evolución.</li>
<li>Valorar punción o drenaje si no mejora en 48 h.</li>
</ul>
</div>
</div>
<div id="artritis_comunitaria" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-users text-red-700 fa-fw"></i> Artritis Infecciosa - Comunitaria</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
<span class="pathogen-item bg-red-100 text-red-700 px-3 py-1 rounded-full text-sm font-medium">Estreptococos</span>
<span class="pathogen-item bg-pink-100 text-pink-700 px-3 py-1 rounded-full text-sm font-medium">N. gonorrhoeae</span>
<span class="pathogen-item bg-cyan-100 text-cyan-700 px-3 py-1 rounded-full text-sm font-medium">Bacilos G(-)</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-prescription text-green-500 fa-fw"></i> Elección IV</div>
<p class="text-base text-gray-700">Cloxacilina 2 g IV c/4 h + Ceftriaxona 2 g IV/24 h.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-allergies text-orange-500 fa-fw"></i> Alergia BL</div>
<p class="text-base text-gray-700">Aztreonam 2 g IV c/8 h + Linezolid 600 mg IV c/12 h.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Artrocentesis y hemocultivos iniciales.</li>
<li>Drenaje quirúrgico precoz; 4-6 semanas de ATB para S. aureus.</li>
</ul>
</div>
</div>
<div id="artritis_nosocomial" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-hospital-user text-purple-600 fa-fw"></i> Artritis Infecciosa - Nosocomial/Post-Infiltración</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-blue-100 text-blue-700 px-3 py-1 rounded-full text-sm font-medium">Staf. Coagulasa-neg.</span>
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
<span class="pathogen-item bg-teal-100 text-teal-700 px-3 py-1 rounded-full text-sm font-medium">P. aeruginosa</span>
<span class="pathogen-item bg-gray-100 text-gray-700 px-3 py-1 rounded-full text-sm font-medium">Cutibacterium acnes</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> Elección</div>
<p class="text-base text-gray-700">Daptomicina 8-10 mg/kg IV/24 h + Ceftazidima 2 g IV c/8 h.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-allergies text-orange-500 fa-fw"></i> Alergia BL</div>
<p class="text-base text-gray-700">Daptomicina + Aztreonam 2 g IV c/8 h.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<p class="text-base text-gray-700">Artrocentesis y drenaje repetido; 4-6 semanas de tratamiento.</p>
</div>
</div>
<div id="artritis_mordedura" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-dog text-green-800 fa-fw"></i> Artritis Infecciosa - Herida/Mordedura</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-gray-100 text-gray-700 px-3 py-1 rounded-full text-sm font-medium">Polimicrobiana</span>
<span class="pathogen-item bg-orange-100 text-orange-700 px-3 py-1 rounded-full text-sm font-medium">Pasteurella spp.</span>
<span class="pathogen-item bg-purple-100 text-purple-700 px-3 py-1 rounded-full text-sm font-medium">Eikenella corrodens</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-green-600">
<div class="treatment-title text-base font-semibold text-green-800 mb-1.5 flex items-center gap-2"><i class="fas fa-clinic-medical text-green-500 fa-fw"></i> Sin ingreso</div>
<p class="text-base text-gray-700">Amox/Clav 875/125 mg VO c/8 h.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-red-600">
<div class="treatment-title text-base font-semibold text-red-800 mb-1.5 flex items-center gap-2"><i class="fas fa-hospital text-red-500 fa-fw"></i> Con ingreso</div>
<p class="text-base text-gray-700">Amox/Clav 2 g IV c/8 h ± Metronidazol 500 mg IV c/8 h.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<p class="text-base text-gray-700">Artrocentesis y drenaje; 4-6 semanas tratamiento según germen.</p>
</div>
</div>
<div id="espondilo_comunitaria" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-bone text-indigo-600 fa-fw"></i> Espondilodiscitis/Osteomielitis Aguda - Comunitaria</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
<span class="pathogen-item bg-red-100 text-red-700 px-3 py-1 rounded-full text-sm font-medium">Estreptococos</span>
<span class="pathogen-item bg-cyan-100 text-cyan-700 px-3 py-1 rounded-full text-sm font-medium">Bacilos G(-)</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-prescription text-green-500 fa-fw"></i> Elección</div>
<p class="text-base text-gray-700">Cloxacilina 2 g IV c/4 h + Ceftriaxona 2 g IV/24 h.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-allergies text-orange-500 fa-fw"></i> Alergia BL</div>
<p class="text-base text-gray-700">Aztreonam 2 g IV c/8 h + Linezolid 600 mg IV c/12 h.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Hemocultivos y biopsia ósea pre-ATB.</li>
<li>Duración ≥ 6 semanas; valorar cirugía si abscesos.</li>
</ul>
</div>
</div>
<div id="espondilo_nosocomial" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-hospital text-red-600 fa-fw"></i> Espondilodiscitis/Osteomielitis Aguda - Nosocomial</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-blue-100 text-blue-700 px-3 py-1 rounded-full text-sm font-medium">Staf. Coag-neg.</span>
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
<span class="pathogen-item bg-teal-100 text-teal-700 px-3 py-1 rounded-full text-sm font-medium">P. aeruginosa</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> Elección</div>
<p class="text-base text-gray-700">Daptomicina 8-10 mg/kg IV/24 h + Ceftazidima 2 g IV c/8 h.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-allergies text-orange-500 fa-fw"></i> Alergia BL</div>
<p class="text-base text-gray-700">Daptomicina + Aztreonam 2 g IV c/8 h.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<p class="text-base text-gray-700">Hemocultivos y biopsia; duración ≥ 6 semanas.</p>
</div>
</div>
<div id="pie_punzante" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-shoe-prints text-blue-700 fa-fw"></i> Osteomielitis Aguda - Pie Punzante</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-teal-100 text-teal-700 px-3 py-1 rounded-full text-sm font-medium">P. aeruginosa</span>
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-green-600">
<div class="treatment-title text-base font-semibold text-green-800 mb-1.5 flex items-center gap-2"><i class="fas fa-clinic-medical text-green-500 fa-fw"></i> Sin ingreso</div>
<p class="text-base text-gray-700">Ciprofloxacino 750 mg VO c/12 h x7-14 días.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-red-600">
<div class="treatment-title text-base font-semibold text-red-800 mb-1.5 flex items-center gap-2"><i class="fas fa-hospital text-red-500 fa-fw"></i> Con ingreso</div>
<p class="text-base text-gray-700">Ceftazidima 2 g IV c/8 h. Si alergia BL: Ciprofloxacino 400 mg IV c/8 h.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<p class="text-base text-gray-700">Valorar desbridamiento quirúrgico.</p>
</div>
</div>
<div id="insuf_vascular" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-socks text-yellow-600 fa-fw"></i> Osteomielitis - Insuficiencia Vascular</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-gray-100 text-gray-700 px-3 py-1 rounded-full text-sm font-medium">Polimicrobiana</span>
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
<span class="pathogen-item bg-cyan-100 text-cyan-700 px-3 py-1 rounded-full text-sm font-medium">Bacilos G(-)</span>
<span class="pathogen-item bg-purple-100 text-purple-700 px-3 py-1 rounded-full text-sm font-medium">Anaerobios</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-green-600">
<div class="treatment-title text-base font-semibold text-green-800 mb-1.5 flex items-center gap-2"><i class="fas fa-clinic-medical text-green-500 fa-fw"></i> Sin ingreso</div>
<p class="text-base text-gray-700">Amox/Clav 875/125 mg VO c/8 h.</p>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-red-600">
<div class="treatment-title text-base font-semibold text-red-800 mb-1.5 flex items-center gap-2"><i class="fas fa-hospital text-red-500 fa-fw"></i> Con ingreso</div>
<p class="text-base text-gray-700">Piperacilina/Tazobactam 4.5 g IV c/6 h. Alergia BL: Aztreonam 2 g IV c/8 h + Metronidazol 500 mg IV c/8 h.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<p class="text-base text-gray-700">Duración ≥ 6 semanas; multisciplinar: vascular, quirúrgico, descarga.</p>
</div>
</div>
<div id="osteomielitis_cronica" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-history text-gray-700 fa-fw"></i> Osteomielitis Crónica</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-blue-100 text-blue-700 px-3 py-1 rounded-full text-sm font-medium">Coag-neg.</span>
<span class="pathogen-item bg-purple-100 text-purple-700 px-3 py-1 rounded-full text-sm font-medium">Enterococcus</span>
<span class="pathogen-item bg-cyan-100 text-cyan-700 px-3 py-1 rounded-full text-sm font-medium">Bacilos G(-)</span>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>No ATB empírico; always dirigir según cultivo.</li>
<li>Cirugía: desbridamiento, resección de secuestros.</li>
<li>ATB dirigido, mín. 8 semanas; quinolonas + rifampicina en G(+).</li>
</ul>
</div>
</div>
<div id="prot_precoz" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-screwdriver text-blue-400 fa-fw"></i> Infección Protésica - Precoz</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
<span class="pathogen-item bg-blue-100 text-blue-700 px-3 py-1 rounded-full text-sm font-medium">Coag-neg.</span>
<span class="pathogen-item bg-teal-100 text-teal-700 px-3 py-1 rounded-full text-sm font-medium">P. aeruginosa</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> Elección</div>
<p class="text-base text-gray-700">Ceftazidima 2 g IV c/8 h + Daptomicina 8-10 mg/kg IV/24 h.</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>Tomar muestra periprotésica (&gt;=5 biopsias).</li>
<li>Desbridamiento + retención protésica.</li>
<li>ATB IV 2 sem + VO hasta min. 8 semanas.</li>
</ul>
</div>
</div>
<div id="prot_hematogena" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-tint text-red-400 fa-fw"></i> Infección Protésica - Hematógena Aguda</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
<span class="pathogen-item bg-blue-100 text-blue-700 px-3 py-1 rounded-full text-sm font-medium">Coag-neg.</span>
<span class="pathogen-item bg-cyan-100 text-cyan-700 px-3 py-1 rounded-full text-sm font-medium">Bacilos G(-)</span>
</div>
<div class="treatment-option bg-white rounded-lg p-3 my-3 border-l-4 border-blue-600">
<div class="treatment-title text-base font-semibold text-blue-800 mb-1.5 flex items-center gap-2"><i class="fas fa-check-circle text-green-500 fa-fw"></i> Elección</div>
<p class="text-base text-gray-700">Ceftazidima + Daptomicina (mismas dosis).</p>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<p class="text-base text-gray-700">Hemocultivos + biopsia; desbridamiento y retención.</p>
</div>
</div>
<div id="prot_cronica" class="treatment-card bg-white rounded-lg shadow-sm p-5 border border-gray-200 mb-6">
<h2 class="text-base font-bold text-gray-800 mb-3 flex items-center gap-2"><i class="fas fa-calendar-alt text-gray-600 fa-fw"></i> Infección Protésica - Crónica Tardía</h2>
<div class="pathogen-list flex flex-wrap gap-2 my-2">
<span class="pathogen-item bg-blue-100 text-blue-700 px-3 py-1 rounded-full text-sm font-medium">Coag-neg.</span>
<span class="pathogen-item bg-yellow-100 text-yellow-700 px-3 py-1 rounded-full text-sm font-medium">S. aureus</span>
<span class="pathogen-item bg-cyan-100 text-cyan-700 px-3 py-1 rounded-full text-sm font-medium">Bacilos G(-)</span>
</div>
<div class="note-box bg-amber-50 border-l-4 border-amber-500 p-3 mt-4 rounded-r-lg">
<div class="note-title text-base font-semibold text-amber-800 mb-1.5 flex items-center gap-2"><i class="fas fa-info-circle text-blue-500 fa-fw"></i> Observaciones</div>
<ul class="list-disc list-outside ml-5 text-base text-gray-700 space-y-1">
<li>No ATB empírico; muestras intraoperatorias.</li>
<li>Recambio protésico en 2 tiempos + ATB IV 1-2 sem + VO hasta 6 semanas.</li>
</ul>
</div>
</div>