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| TxAgent: An AI Agent for Therapeutic Reasoning Across a Universe of Tools |
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| <section class="hero is-small"> |
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| <h2 class="title is-2 has-text-centered">TxAgent model</h2> |
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| src="static/images/txagent.jpg" |
| alt="TxAgent model" |
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| <h2 class="title is-3">What is TxAgent?</h2> |
| <div class="content has-text-justified"> |
| <p> |
| Precision therapeutics require multimodal adaptive models that |
| generate personalized treatment recommendations. We introduce |
| TxAgent, an AI agent that leverages multi-step reasoning and |
| real-time biomedical knowledge retrieval across a toolbox of 211 |
| tools to analyze drug interactions, contraindications, and |
| patient-specific treatment strategies. TxAgent evaluates how |
| drugs interact at molecular, pharmacokinetic, and clinical |
| levels, identifies contraindications based on patient |
| comorbidities and concurrent medications, and tailors treatment |
| strategies to individual patient characteristics, including age, |
| genetic factors, and disease progression. TxAgent retrieves and |
| synthesizes evidence from multiple biomedical sources, assesses |
| interactions between drugs and patient conditions, and refines |
| treatment recommendations through iterative reasoning. It |
| selects tools based on task objectives and executes structured |
| function calls to solve therapeutic tasks that require clinical |
| reasoning and cross-source validation. The ToolUniverse |
| consolidates 211 tools from trusted sources, including all US |
| FDA-approved drugs since 1939 and validated clinical insights |
| from Open Targets. TxAgent outperforms leading LLMs, tool-use |
| models, and reasoning agents across five new benchmarks: DrugPC, |
| BrandPC, GenericPC, TreatmentPC, and DescriptionPC, covering |
| 3,168 drug reasoning tasks and 456 personalized treatment |
| scenarios. It achieves 92.1% accuracy in open-ended drug |
| reasoning tasks, surpassing GPT-4o by up to 25.8% and |
| outperforming DeepSeek-R1 (671B) in structured multi-step |
| reasoning. TxAgent generalizes across drug name variants and |
| descriptions, maintaining a variance of <0.01 between brand, |
| generic, and description-based drug references, exceeding |
| existing tool-use LLMs by over 55%. By integrating multi-step |
| inference, real-time knowledge grounding, and tool- assisted |
| decision-making, TxAgent ensures that treatment recommendations |
| align with established clinical guidelines and real-world |
| evidence, reducing the risk of adverse events and improving |
| therapeutic decision-making. |
| </p> |
| </div> |
| </div> |
| </div> |
| </div> |
| </section> |
| |
|
|
| |
| <section class="hero is-small"> |
| <div class="hero-body content-container"> |
| <div class="container"> |
| <h2 class="title is-2 has-text-centered">TxAgent capabilities</h2> |
| <div class="container is-centered has-text-centered"> |
| <img |
| src="static/images/txagent_capabilities.jpg" |
| alt="TxAgent Capabilities" |
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| <div class="container is-centered has-text-centered is-max-desktop"> |
| <section class="section hero is-light py-2 content"> |
| <div class="has-text-left py-2"> |
| <ul> |
| <li> |
| <b>Knowledge grounding using tool calls</b>: TxAgent |
| utilizes tools to obtain verified knowledge and provides |
| outputs based on it. |
| </li> |
| <li> |
| <b>Goal-oriented tool selection</b>: TxAgent proactively |
| requests tools from ToolUniverse using the ToolRAG model and |
| selects and applies the most suitable tool from the |
| available candidates. |
| </li> |
| <li> |
| <b>Problem solving with multi-step reasoning</b>: TxAgent |
| manages complex tasks or unexpected responses from tools |
| through multiple iterations of thought and function calls. |
| </li> |
| <li> |
| <b>Leveraging constantly updated knowledge bases</b>: |
| TxAgent accesses continuously updated databases via tools to |
| handle problems that go beyond the TxAgent’s intrinsic |
| knowledge. |
| </li> |
| </ul> |
| </div> |
| </section> |
| </div> |
| </div> |
| </div> |
| </section> |
| |
|
|
| |
| <section class="section" id="BibTeX"> |
| <div class="container is-max-desktop content"> |
| <h2 class="title">BibTeX</h2> |
| <pre><code>@misc{gao2025txagent, |
| title={TxAgent: An AI Agent for Therapeutic Reasoning Across a Universe of Tools}, |
| author={Shanghua Gao and Richard Zhu and Zhenglun Kong and Ayush Noori and Xiaorui Su and Curtis Ginder and Theodoros Tsiligkaridis and Marinka Zitnik}, |
| year={2025}, |
| eprint={2503.10970}, |
| archivePrefix={arXiv}, |
| primaryClass={cs.AI}, |
| url={https://arxiv.org/abs/2503.10970}, |
| }</code></pre> |
| </div> |
| </section> |
| |
|
|
| |
| <section class="section" id="BibTeX"> |
| <div class="container is-max-desktop content"> |
| <h2 class="title">Contact</h2> |
| <p>If you have any questions or suggestions, please email |
| <a href="mailto:shanghuagao@gmail.com">Shanghua Gao</a> and |
| <a href="mailto:marinka@hms.harvard.edu">Marinka Zitnik</a>. |
| </p> |
| </div> |
| </section> |
| |
|
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| <p> |
| We gratefully acknowledge the support of NIH R01-HD108794, NSF CAREER 2339524, US DoD FA8702-15-D-0001, Harvard Data Science Initiative, Amazon Faculty Research, Google Research Scholar Program, AstraZeneca Research, Roche Alliance with Distinguished Scientists, Sanofi iDEA-iTECH, Pfizer Research, Gates Foundation (INV-079038), Chan Zuckerberg Initiative, John and Virginia Kaneb Fellowship at Harvard Medical School, Biswas Computational Biology Initiative in partnership with the Milken Institute, Harvard Medical School Dean's Innovation Fund for the Use of Artificial Intelligence, and Kempner Institute for the Study of Natural and Artificial Intelligence at Harvard University. Any opinions, findings, conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the funders. |
| We thank Owen Queen and Thomas Hartvigsen for their valuable discussions on this project and NVIDIA AI for providing access to DeepSeek R1 models. |
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|
| <script> |
| const dataDict = { |
| "Adverse Events, Risks, Safety": { |
| "Adverse Events and Alarms": [ |
| "get_drug_adverse_events_by_chemblId", |
| "get_drug_name_by_adverse_reaction", |
| "get_adverse_reactions_by_drug_name", |
| "get_drug_names_by_alarm", |
| "get_alarms_by_drug_name", |
| ], |
| "Warnings and Risks": [ |
| "get_drug_warnings_by_chemblId", |
| "get_drug_names_by_boxed_warning", |
| "get_boxed_warning_info_by_drug_name", |
| "get_drug_name_by_warnings", |
| "get_warnings_by_drug_name", |
| "get_warnings_and_cautions_by_drug_name", |
| "get_drug_names_by_warnings_and_cautions", |
| "get_drug_names_by_risk", |
| "get_risk_info_by_drug_name", |
| "get_user_safety_warning_by_drug_names", |
| "get_drug_names_by_user_safety_warning", |
| "get_drug_names_by_food_safety_warnings", |
| "get_drug_withdrawn_blackbox_status_by_chemblId", |
| ], |
| "Nonclinical Toxicology": [ |
| "get_drug_names_by_nonclinical_toxicology_info", |
| "get_nonclinical_toxicology_info_by_drug_name", |
| ], |
| "Carcinogenic, Mutagenic, Fertility, Impairment Info": [ |
| "get_drug_names_by_carcinogenic, mutagenic, fertility, impairment_info", |
| "get_carcinogenic, mutagenic, fertility, impairment_info_by_drug_name", |
| ], |
| "Other Safety Info": [ |
| "get_drug_name_by_other_safety_info", |
| "get_other_safety_info_by_drug_name", |
| ], |
| "Safety Summary": [ |
| "get_drug_names_by_safety_summary", |
| "get_safety_summary_by_drug_name", |
| ], |
| Contraindications: [ |
| "get_drug_names_by_contraindications", |
| "get_contraindications_by_drug_name", |
| "get_do_not_use_info_by_drug_name", |
| ], |
| Precautions: [ |
| "get_drug_names_by_general_precautions", |
| "get_general_precautions_by_drug_name", |
| "get_drug_name_by_precautions", |
| "get_precautions_by_drug_name", |
| ], |
| "Nonteratogenic Effects": [ |
| "get_drug_names_by_nonteratogenic_effects", |
| "get_nonteratogenic_effects_by_drug_name", |
| ], |
| "Teratogenic Effects": [ |
| "get_drug_names_by_teratogenic_effects", |
| "get_teratogenic_effects_by_drug_name", |
| ], |
| "Overdosage Info": [ |
| "get_drug_names_by_overdosage_info", |
| "get_overdosage_info_by_drug_name", |
| ], |
| "Stop Use Info": [ |
| "get_drug_name_by_stop_use_info", |
| "get_stop_use_info_by_drug_name", |
| ], |
| "Lab Test Interference": [ |
| "get_drug_names_by_lab_test_interference", |
| "get_lab_test_interference_info_by_drug_name", |
| ], |
| "Residue Warning": [ |
| "get_drug_names_by_residue_warning", |
| "get_residue_warning_by_drug_name", |
| ], |
| "Environmental Warning": [ |
| "get_drug_name_by_environmental_warning", |
| "get_environmental_warning_by_drug_name", |
| ], |
| "Target Safety Profile": ["get_target_safety_profile_by_ensemblID"], |
| }, |
| "Addiction and Abuse": { |
| "Drug Abuse": [ |
| "get_drug_names_by_abuse_info", |
| "get_abuse_info_by_drug_name", |
| "get_drug_name_by_abuse_types_and_related_adverse_reactions_and_controlled_substance_status", |
| "get_abuse_types_and_related_adverse_reactions_and_controlled_substance_status_by_drug_name", |
| ], |
| "Drug Dependence": [ |
| "get_drug_name_by_dependence_info", |
| "get_dependence_info_by_drug_name", |
| ], |
| "Controlled Substance": [ |
| "get_drug_names_by_controlled_substance_DEA_schedule", |
| "get_controlled_substance_DEA_schedule_info_by_drug_name", |
| "get_drug_name_by_abuse_types_and_related_adverse_reactions_and_controlled_substance_status", |
| "get_abuse_types_and_related_adverse_reactions_and_controlled_substance_status_by_drug_name", |
| ], |
| }, |
| "Drug Patient Populations": { |
| Pregnancy: [ |
| "get_drug_names_by_pregnancy_effects_info", |
| "get_pregnancy_effects_info_by_drug_name", |
| "get_drug_name_by_pregnancy_or_breastfeeding_info", |
| "get_pregnancy_or_breastfeeding_info_by_drug_name", |
| "get_drug_name_by_labor_and_delivery_info", |
| "get_labor_and_delivery_info_by_drug_name", |
| "get_drug_names_by_teratogenic_effects", |
| "get_teratogenic_effects_by_drug_name", |
| ], |
| "Nursing Mother": [ |
| "get_drug_names_by_info_for_nursing_mothers", |
| "get_info_for_nursing_mothers_by_drug_name", |
| "get_drug_name_by_pregnancy_or_breastfeeding_info", |
| "get_pregnancy_or_breastfeeding_info_by_drug_name", |
| ], |
| "Pediatric Use": [ |
| "get_drug_names_by_pediatric_use", |
| "get_pediatric_use_info_by_drug_name", |
| "get_drug_names_by_child_safety_info", |
| "get_child_safety_info_by_drug_name", |
| ], |
| "General Patient Pop. Info": [ |
| "get_drug_names_by_population_use", |
| "get_population_use_info_by_drug_name", |
| ], |
| "Geriatric Use": [ |
| "get_drug_names_by_geriatric_use", |
| "get_geriatric_use_info_by_drug_name", |
| ], |
| }, |
| "Drug Administration and Handling": { |
| Storage: [ |
| "get_drug_name_by_storage_and_handling_info", |
| "get_storage_and_handling_info_by_drug_name", |
| "get_dosage_and_storage_information_by_drug_name", |
| ], |
| "Safe Handling": [ |
| "get_drug_names_by_safe_handling_warning", |
| "get_safe_handling_warnings_by_drug_name", |
| ], |
| Disposal: [ |
| "get_drug_names_by_disposal_info", |
| "get_disposal_info_by_drug_name", |
| ], |
| Dosing: [ |
| "get_drug_name_by_dosage_info", |
| "get_drug_names_by_dosage_forms_and_strengths_info", |
| "get_dosage_forms_and_strengths_by_drug_name", |
| "get_dosage_and_storage_information_by_drug_name", |
| ], |
| "Route of Administration": [ |
| "get_drug_names_by_route", |
| "get_route_info_by_drug_name", |
| ], |
| "Setup Instructions": [ |
| "get_drug_names_by_assembly_installation_info", |
| "get_assembly_installation_info_by_drug_name", |
| "get_drug_name_by_calibration_instructions", |
| "get_calibration_instructions_by_drug_name", |
| ], |
| "General Instructions": [ |
| "get_drug_names_by_instructions_for_use", |
| "get_instructions_for_use_by_drug_name", |
| ], |
| Accessories: [ |
| "get_drug_names_by_accessories", |
| "get_accessories_info_by_drug_name", |
| ], |
| "Assoc. Devices": [ |
| "get_drug_name_by_device_use", |
| "get_device_use_by_drug_name", |
| ], |
| }, |
| Pharmacology: { |
| Pharmacokinetics: [ |
| "get_drug_names_by_pharmacokinetics", |
| "get_pharmacokinetics_by_drug_name", |
| ], |
| Pharmacodynamics: [ |
| "get_drug_name_by_pharmacodynamics", |
| "get_pharmacodynamics_by_drug_name", |
| ], |
| "Clinical Pharmacology": [ |
| "get_drug_names_by_clinical_pharmacology", |
| "get_clinical_pharmacology_by_drug_name", |
| ], |
| "Animal Pharmacology": [ |
| "get_drug_names_by_animal_pharmacology_info", |
| "get_animal_pharmacology_info_by_drug_name", |
| ], |
| }, |
| "Drug Use, Mechanism, Composition": { |
| "Mechanism of Action": [ |
| "get_mechanism_of_action_by_drug_name", |
| "get_drug_names_by_mechanism_of_action", |
| "get_drug_mechanisms_of_action_by_chemblId", |
| ], |
| Ingredients: [ |
| "get_active_ingredient_info_by_drug_name", |
| "get_drug_names_by_active_ingredient", |
| "get_drug_name_by_inactive_ingredient", |
| "get_inactive_ingredient_info_by_drug_name", |
| "get_drug_names_by_ingredient", |
| "get_ingredients_by_drug_name", |
| "get_active_ingredient_application_number_manufacturer_name_NDC_number_administration_route_by_drug_name", |
| ], |
| Indication: [ |
| "get_drug_names_by_indication", |
| "get_indications_by_drug_name", |
| "get_drug_indications_by_chemblId", |
| "get_approved_indications_by_drug_chemblId", |
| "get_purpose_info_by_drug_name", |
| ], |
| }, |
| "ID and Labeling Tools": { |
| "Drug Name/Description and ID Map": [ |
| "get_brand_name_generic_name", |
| "get_drug_synonyms_by_chemblId", |
| "get_drug_trade_names_by_chemblId", |
| "get_drug_description_by_chemblId", |
| "get_drug_id_description_by_name", |
| "get_known_drugs_by_drug_chemblId", |
| ], |
| "Drug Label Document and Set IDs": [ |
| "get_drug_name_by_document_id", |
| "get_document_id_by_drug_name", |
| "get_drug_name_by_set_id", |
| "get_drug_name_by_application_number_NUI_identifier_SPL_document_ID_SPL_set_ID", |
| ], |
| "Disease Name/Description and ID Map": [ |
| "get_disease_synonyms_by_efoId", |
| "get_disease_id_description_by_name", |
| "get_disease_description_by_efoId", |
| "get_drug_name_by_set_id", |
| ], |
| "Target Name/Description and ID Map": [ |
| "get_target_id_description_by_name", |
| "get_target_synonyms_by_ensemblID", |
| ], |
| "App Num., Manufacturer Name, Other IDs": [ |
| "get_active_ingredient_application_number_manufacturer_name_NDC_number_administration_route_by_drug_name", |
| "get_drug_names_by_application_number_manufacturer_name_NDC_number", |
| "get_drug_name_by_application_number_NUI_identifier_SPL_document_ID_SPL_set_ID", |
| ], |
| "Phenotype Name and ID Map": [ |
| "get_phenotype_by_HPO_ID", |
| "get_HPO_ID_by_phenotype", |
| ], |
| }, |
| "General Clinical Annotations": { |
| "SPL Indexing Data Elements and Unclassified Section": [ |
| "get_drug_names_by_spl_indexing_data_elements", |
| "get_spl_indexing_data_elements_by_drug_name", |
| "get_spl_unclassified_section_by_drug_name", |
| ], |
| "Label Effective Time": [ |
| "get_drug_names_by_effective_time", |
| "get_effective_time_by_drug_name", |
| ], |
| "Approval Status": ["get_drug_approval_status_by_chemblId"], |
| "Dear Health Care Provider Letter and Recent Changes": [ |
| "get_dear_health_care_provider_letter_info_by_drug_name", |
| "get_drug_names_by_dear_health_care_provider_letter_info", |
| "get_recent_changes_by_drug_name", |
| ], |
| "Health Claims": [ |
| "get_drug_names_by_health_claim", |
| "get_health_claims_by_drug_name", |
| ], |
| "Questions Contact": ["get_contact_for_questions_info_by_drug_name"], |
| }, |
| "Clinical Laboratory Info": { |
| "Lab Tests": [ |
| "get_drug_names_by_lab_tests", |
| "get_lab_tests_by_drug_name", |
| ], |
| Microbiology: [ |
| "get_drug_name_by_microbiology", |
| "get_microbiology_info_by_drug_name", |
| ], |
| }, |
| "General Info for Patients and Relatives": { |
| "Consult Doctor/Pharmacist": [ |
| "get_drug_name_by_info_on_doctor_consultation", |
| "get_info_on_doctor_consultation_by_drug_name", |
| "get_drug_names_by_info_on_consulting_doctor, pharmacist_for_drug_interactions", |
| "get_info_on_consulting_doctor, pharmacist_for_drug_interactions_by_drug_name", |
| ], |
| "Info for Owners/Caregivers": [ |
| "get_drug_names_by_information_for_owners_or_caregivers", |
| "get_information_for_owners_or_caregivers_by_drug_name", |
| ], |
| "Drug Info for Patients": [ |
| "get_info_for_patients_by_drug_name", |
| "get_drug_name_by_principal_display_panel", |
| "get_principal_display_panel_by_drug_name", |
| "get_drug_names_by_medication_guide", |
| "get_medication_guide_info_by_drug_name", |
| "get_drug_name_from_patient_package_insert", |
| "get_patient_package_insert_from_drug_name", |
| "get_drug_names_by_patient_medication_info", |
| "get_patient_medication_info_by_drug_name", |
| "get_when_using_info", |
| ], |
| "Avoid While Using Drug": ["get_when_using_info"], |
| }, |
| "Disease, Phenotype, Target, Drug Links": { |
| "Drug-Disease Associations": [ |
| "get_similar_entities_by_drug_chemblId", |
| "get_similar_entities_by_disease_efoId", |
| "get_assoc._drugs_by_disease_efoId", |
| "get_assoc._diseases_by_drug_chemblId", |
| ], |
| "Drug-Target Associations": [ |
| "get_similar_entities_by_drug_chemblId", |
| "get_similar_entities_by_target_ensemblID", |
| "get_assoc._drugs_by_target_ensemblID", |
| "get_assoc._targets_by_drug_chemblId", |
| ], |
| "Target-Disease/Phenotype Associations": [ |
| "get_similar_entities_by_target_ensemblID", |
| "get_similar_entities_by_disease_efoId", |
| "get_assoc._diseases_by_target_ensemblID", |
| "get_assoc._targets_by_disease_efoId", |
| "get_assoc._diseases_phenotypes_by_target_ensemblID", |
| ], |
| "Disease-Disease/Phenotype Associations": [ |
| "get_similar_entities_by_disease_efoId", |
| "get_joint_assoc._diseases_by_HPO_ID_list", |
| "get_assoc._phenotypes_by_disease_efoId", |
| ], |
| "Target-Target Associations": [ |
| "get_target_homologues_by_ensemblID", |
| "get_similar_entities_by_target_ensemblID", |
| "get_target_interactions_by_ensemblID", |
| ], |
| "Drug-Drug Associations": [ |
| "get_drug_names_by_drug_interactions", |
| "get_drug_interactions_by_drug_name", |
| "get_similar_entities_by_drug_chemblId", |
| ], |
| Pharmacogenomics: [ |
| "drug_pharmacogenomics_data", |
| "get_drug_name_by_pharmacogenomics", |
| "get_pharmacogenomics_info_by_drug_name", |
| ], |
| }, |
| "Biological Annotation Tools": { |
| "Target Biological Annotation": [ |
| "get_target_gene_ontology_by_ensemblID", |
| "get_target_genomic_location_by_ensemblID", |
| "get_target_subcellular_locations_by_ensemblID", |
| "get_target_classes_by_ensemblID", |
| "get_biological_mouse_models_by_ensemblID", |
| ], |
| "Disease Biological Annotation": [ |
| "get_disease_therapeutic_areas_by_efoId", |
| "get_disease_ancestors_parents_by_efoId", |
| "get_disease_descendants_children_by_efoId", |
| "get_disease_locations_by_efoId", |
| ], |
| "Gene Ontology": [ |
| "get_gene_ontology_terms_by_goID", |
| "get_target_gene_ontology_by_ensemblID", |
| ], |
| "Drug Parent Child Molecules": [ |
| "get_parent_child_molecules_by_drug_chembl_ID", |
| ], |
| }, |
| Publications: { |
| Publications: [ |
| "get_publications_by_disease_efoId", |
| "get_publications_by_target_ensemblID", |
| "get_publications_by_drug_chemblId", |
| ], |
| "Clinical Studies": [ |
| "get_drug_names_by_clinical_studies", |
| "get_clinical_studies_info_by_drug_name", |
| ], |
| "Reference Documents": [ |
| "get_drug_name_by_reference", |
| "get_reference_info_by_drug_name", |
| ], |
| }, |
| Search: { |
| "Search Tools": [ |
| "multi_entity_search_by_query_string", |
| "search_category_counts_by_query_string", |
| ], |
| }, |
| "Target Characterization": { |
| "Target Therapeutic Potential": [ |
| "get_target_tractability_by_ensemblID", |
| "get_target_enabling_packages_by_ensemblID", |
| "get_chemical_probes_by_target_ensemblID", |
| "get_target_constraint_info_by_ensemblID", |
| ], |
| }, |
| }; |
| function toSentenceCase(str) { |
| |
| let formatted = str.replace(/_/g, " ").toLowerCase(); |
| |
| formatted = formatted.charAt(0).toUpperCase() + formatted.slice(1); |
| |
| formatted = formatted.replace(/chemblid/gi, "ChEMBL ID"); |
| formatted = formatted.replace(/ensemblid/gi, "Ensembl ID"); |
| formatted = formatted.replace(/efoid/gi, "EFO ID"); |
| formatted = formatted.replace(/hpo/gi, "HPO"); |
| formatted = formatted.replace(/ids/gi, "IDs"); |
| formatted = formatted.replace( |
| /application number nui identifier spl document id spl set id/gi, |
| "app. number, NUI identifier, SPL doc. ID, SPL set ID" |
| ); |
| formatted = formatted.replace( |
| /Get active ingredient application number manufacturer name ndc number administration route/gi, |
| "get active ingredient, app. num., manufacturer, NDC num., administration" |
| ); |
| formatted = formatted.replace( |
| /Get drug name by application number manufacturer name ndc number/gi, |
| "get drug name by app. number, manufacturer, NDC number" |
| ); |
| formatted = formatted.replace(/goID/gi, "GO ID"); |
| formatted = formatted.replace( |
| /controlled substance dea schedule/gi, |
| "DEA schedule" |
| ); |
| formatted = formatted.replace(/spl/gi, "SPL"); |
| |
| return formatted.replace(/\bId\b/gi, "ID"); |
| } |
| |
| |
| let currentLevel = 1; |
| let currentTier1 = null; |
| let chart; |
| let currentTier1Color = null; |
| let currentTier2Color = null; |
| |
| |
| let sortedDataDict = {}; |
| |
| |
| function sortDataDict() { |
| |
| const tier1Totals = {}; |
| |
| for (const topKey in dataDict) { |
| let total = 0; |
| const tier2Totals = {}; |
| |
| |
| for (const subKey in dataDict[topKey]) { |
| const count = dataDict[topKey][subKey].length; |
| tier2Totals[subKey] = count; |
| total += count; |
| } |
| |
| tier1Totals[topKey] = { |
| total: total, |
| tier2Totals: tier2Totals, |
| }; |
| } |
| |
| |
| const sortedTier1Keys = Object.keys(tier1Totals).sort( |
| (a, b) => tier1Totals[b].total - tier1Totals[a].total |
| ); |
| |
| |
| sortedDataDict = {}; |
| |
| for (const topKey of sortedTier1Keys) { |
| sortedDataDict[topKey] = {}; |
| |
| |
| const tier2Totals = tier1Totals[topKey].tier2Totals; |
| const sortedTier2Keys = Object.keys(tier2Totals).sort( |
| (a, b) => tier2Totals[b] - tier2Totals[a] |
| ); |
| |
| |
| for (const subKey of sortedTier2Keys) { |
| sortedDataDict[topKey][subKey] = dataDict[topKey][subKey]; |
| } |
| } |
| |
| return sortedDataDict; |
| } |
| |
| |
| function loadTier1() { |
| currentLevel = 1; |
| currentTier1 = null; |
| const newData = []; |
| |
| |
| newData.push({ |
| id: "root", |
| name: "ToolUniverse", |
| value: 1, |
| color: "skyblue", |
| }); |
| |
| let index = 1; |
| |
| for (const topKey in sortedDataDict) { |
| |
| let total = 0; |
| const tier2Obj = sortedDataDict[topKey]; |
| for (const subKey in tier2Obj) { |
| total += tier2Obj[subKey].length; |
| } |
| |
| |
| const color = |
| chart.options.colors[(index - 1) % chart.options.colors.length]; |
| |
| |
| const tier1Id = "tier1_" + index; |
| newData.push({ |
| id: tier1Id, |
| parent: "root", |
| name: toSentenceCase(topKey), |
| value: total, |
| originalKey: topKey, |
| color: color, |
| }); |
| |
| |
| let tier2Index = 1; |
| for (const subKey in tier2Obj) { |
| newData.push({ |
| id: tier1Id + "_tier2_" + tier2Index, |
| parent: tier1Id, |
| name: "", |
| |
| value: tier2Obj[subKey].length, |
| originalKey: subKey, |
| color: Highcharts.color(color).brighten(0.1).get(), |
| dataLabels: { enabled: false }, |
| }); |
| tier2Index++; |
| } |
| |
| index++; |
| } |
| chart.series[0].setData(newData, true); |
| chart.setTitle({ text: "ToolUniverse" }); |
| } |
| |
| |
| function loadTier2(topKey) { |
| currentLevel = 2; |
| currentTier1 = topKey; |
| const newData = []; |
| |
| |
| newData.push({ |
| id: "root", |
| name: toSentenceCase(topKey), |
| value: 1, |
| color: Highcharts.color(currentTier1Color).brighten(-0.05).get(), |
| }); |
| |
| let index = 1; |
| const secondLevelObj = sortedDataDict[topKey]; |
| |
| |
| const maxBrighten = 0.2; |
| const brightenStep = |
| Object.keys(secondLevelObj).length > 1 |
| ? maxBrighten / (Object.keys(secondLevelObj).length - 1) |
| : 0; |
| |
| |
| for (const subKey in secondLevelObj) { |
| const parentColor = Highcharts.color(currentTier1Color) |
| .brighten(brightenStep * index) |
| .get(); |
| const tier2Id = "tier2_" + index; |
| newData.push({ |
| id: tier2Id, |
| parent: "root", |
| name: toSentenceCase(subKey), |
| value: secondLevelObj[subKey].length, |
| originalKey: subKey, |
| color: parentColor, |
| }); |
| |
| |
| let tier3Index = 1; |
| const children = secondLevelObj[subKey]; |
| for (const item of children) { |
| newData.push({ |
| id: tier2Id + "_tier3_" + tier3Index, |
| parent: tier2Id, |
| name: "", |
| value: 1, |
| originalKey: item, |
| color: Highcharts.color(parentColor).brighten(0.1).get(), |
| dataLabels: { enabled: false }, |
| }); |
| tier3Index++; |
| } |
| index++; |
| } |
| chart.series[0].setData(newData, true); |
| chart.setTitle({ text: "ToolUniverse: " + toSentenceCase(topKey) }); |
| } |
| |
| |
| |
| function loadTier3(topKey, subKey) { |
| currentLevel = 3; |
| const newData = []; |
| |
| newData.push({ |
| id: "root", |
| name: toSentenceCase(subKey), |
| value: 1, |
| color: Highcharts.color(currentTier2Color).brighten(-0.05).get(), |
| }); |
| let index = 1; |
| const children = sortedDataDict[topKey][subKey]; |
| |
| const maxBrighten = 0.2; |
| const brightenStep = |
| children.length > 1 ? maxBrighten / (children.length - 1) : 0; |
| |
| for (const item of children) { |
| newData.push({ |
| id: "tier3_" + index, |
| parent: "root", |
| name: toSentenceCase(item), |
| value: 1, |
| originalKey: item, |
| color: Highcharts.color(currentTier2Color) |
| .brighten(brightenStep * index) |
| .get(), |
| }); |
| index++; |
| } |
| chart.series[0].setData(newData, true); |
| chart.setTitle({ text: "ToolUniverse: " + toSentenceCase(subKey) }); |
| } |
| |
| |
| chart = Highcharts.chart("tooluniverse-container", { |
| chart: { |
| height: "100%", |
| }, |
| title: { |
| text: "ToolUniverse", |
| }, |
| series: [ |
| { |
| type: "sunburst", |
| data: [], |
| |
| colorByPoint: false, |
| allowDrillToNode: false, |
| dataLabels: { |
| format: "{point.name}", |
| distance: 20, |
| style: { |
| fontSize: "10px", |
| textAlign: "center", |
| width: "80px", |
| whiteSpace: "normal", |
| textOutline: "none", |
| color: "#000000", |
| }, |
| rotation: "auto", |
| }, |
| |
| levels: [ |
| { |
| level: 1, |
| levelSize: { unit: "pixels", value: 40 }, |
| }, |
| { |
| level: 2, |
| levelSize: { unit: "percentage", value: 70 }, |
| }, |
| { |
| level: 3, |
| levelSize: { unit: "pixels", value: 15 }, |
| dataLabels: { enabled: false }, |
| }, |
| ], |
| |
| point: { |
| events: { |
| click: function () { |
| |
| if (this.id === "root") { |
| if (currentLevel === 2) { |
| loadTier1(); |
| } else if (currentLevel === 3) { |
| loadTier2(currentTier1); |
| } |
| } else { |
| |
| if ( |
| currentLevel === 1 && |
| sortedDataDict[this.options.originalKey] |
| ) { |
| currentTier1Color = this.color; |
| loadTier2(this.options.originalKey); |
| } else if ( |
| currentLevel === 2 && |
| currentTier1 && |
| sortedDataDict[currentTier1][this.options.originalKey] |
| ) { |
| currentTier2Color = this.color; |
| loadTier3(currentTier1, this.options.originalKey); |
| } |
| } |
| }, |
| }, |
| }, |
| }, |
| ], |
| tooltip: { |
| headerFormat: "", |
| pointFormat: "<b>{point.name}</b>", |
| }, |
| colors: [ |
| "#FFA15A", |
| "#636efa", |
| "#ab63fa", |
| "#FF6692", |
| "#EF553B", |
| "#00cc96", |
| "#B6E880", |
| "#19d3f3", |
| "#f2ce3f", |
| ], |
| }); |
| |
| |
| sortDataDict(); |
| |
| |
| loadTier1(); |
| </script> |
|
|
