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| [ | |
| { | |
| "name": "get_associated_targets_by_disease_efoId", | |
| "description": "Find targets associated with a specific disease or phenotype based on efoId.", | |
| "label": [ | |
| "Disease", | |
| "Phenotype", | |
| "Target", | |
| "Association", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "efoId": { | |
| "type": "string", | |
| "description": "The efoId of a disease or phenotype.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\nquery associatedTargets($efoId: String!) {\n disease(efoId: $efoId) {\n id\n name\n associatedTargets {\n count\n rows {\n target {\n id\n approvedSymbol\n }\n score\n }\n }\n }\n}\n", | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_associated_diseases_phenotypes_by_target_ensemblID", | |
| "description": "Find diseases or phenotypes associated with a specific target using ensemblId.", | |
| "label": [ | |
| "Target", | |
| "Disease", | |
| "Phenotype", | |
| "Association", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The ensemblId of a target.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\nquery associatedDiseases($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n associatedDiseases {\n count\n rows {\n disease {\n id\n name\n }\n datasourceScores {\n id\n score\n }\n }\n }\n }\n}\n", | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "target_disease_evidence", | |
| "description": "Explore evidence that supports a specific target-disease association. Input is disease efoId and target ensemblID.", | |
| "label": [ | |
| "Target", | |
| "Disease", | |
| "Evidence", | |
| "Association", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "efoId": { | |
| "type": "string", | |
| "description": "The efoId of a disease or phenotype.", | |
| "required": true | |
| }, | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The ensemblId of a target.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\nquery targetDiseaseEvidence($efoId: String!, $ensemblId: String!) {\n disease(efoId: $efoId) {\n id\n name\n evidences(datasourceIds: [\"intogen\"], ensemblIds: [$ensemblId]) {\n count\n rows {\n disease {\n id\n name\n }\n diseaseFromSource\n target {\n id\n approvedSymbol\n }\n mutatedSamples {\n functionalConsequence {\n id\n label\n }\n numberSamplesTested\n numberMutatedSamples\n }\n resourceScore\n significantDriverMethods\n cohortId\n cohortShortName\n cohortDescription\n }\n }\n }\n}\n", | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_drug_warnings_by_chemblId", | |
| "description": "Retrieve warnings for a specific drug using ChEMBL ID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query drugWarnings($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n drugWarnings {\n warningType\n description\n country\n year\n toxicityClass\n chemblIds\n efoIdForWarningClass\n references {\n id\n source\n url\n }\n }\n }\n }\n ", | |
| "label": [ | |
| "Drug", | |
| "AdverseEvents", | |
| "SafetyLiability", | |
| "OpenTarget", | |
| "GraphQL", | |
| "Warnings", | |
| "Safety", | |
| "Withdrawal", | |
| "Toxicity" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_drug_mechanisms_of_action_by_chemblId", | |
| "description": "Retrieve the mechanisms of action associated with a specific drug using chemblId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query drugMechanismsOfAction($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n mechanismsOfAction {\n rows {\n mechanismOfAction\n actionType\n targetName\n targets {\n id\n approvedSymbol\n }\n }\n }\n }\n }\n ", | |
| "label": [ | |
| "Drug", | |
| "MechanismsOfAction", | |
| "Target", | |
| "Pharmacology", | |
| "ChemblId", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_associated_drugs_by_disease_efoId", | |
| "description": "Retrieve known drugs associated with a specific disease by disease efoId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "efoId": { | |
| "type": "string", | |
| "description": "The EFO ID of the disease.", | |
| "required": true | |
| }, | |
| "size": { | |
| "type": "integer", | |
| "description": "Number of entries to fetch, recomanding a large number to avoid missing drugs.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query diseaseKnownDrugs($efoId: String!, $size: Int!, $freeTextQuery: String) {\n disease(efoId: $efoId) {\n id\n name\n knownDrugs(size: $size, freeTextQuery: $freeTextQuery) {\n count\n rows {\n drug {\n id\n name\n tradeNames\n maximumClinicalTrialPhase\n isApproved\n hasBeenWithdrawn\n }\n phase\n status\n mechanismOfAction\n target {\n id\n approvedSymbol\n }\n }\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Please list the drugs associated with the disease with efoId 'EFO_0005548' and filter by 'dopamine'.", | |
| "query": { | |
| "name": "get_associated_drugs_by_disease_efoId", | |
| "arguments": { | |
| "efoId": "EFO_0005548", | |
| "size": 10, | |
| "freeTextQuery": "dopamine" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "OpenTarget", | |
| "Disease", | |
| "Drug", | |
| "Pagination", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_similar_entities_by_disease_efoId", | |
| "description": "Retrieve similar entities for a given disease efoId using a model trained with PubMed.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "efoId": { | |
| "type": "string", | |
| "description": "The EFO ID of the disease.", | |
| "required": true | |
| }, | |
| "threshold": { | |
| "type": "number", | |
| "description": "Threshold similarity between 0 and 1. Only results above threshold are returned.", | |
| "required": true | |
| }, | |
| "size": { | |
| "type": "integer", | |
| "description": "Number of similar entities to fetch.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query diseaseSimilarEntities($efoId: String!, $threshold: Float!, $size: Int!) {\n disease(efoId: $efoId) {\n id\n name\n similarEntities(threshold: $threshold, size: $size) {\n id\n category\n score\n object {\n ... on Disease {\n id\n name\n }\n ... on Target {\n id\n approvedSymbol\n }\n ... on Drug {\n id\n name\n }\n }\n }\n }\n }\n ", | |
| "label": [ | |
| "Disease", | |
| "Similarity", | |
| "Model", | |
| "Entities", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_similar_entities_by_drug_chemblId", | |
| "description": "Retrieve similar entities for a given drug chemblId using a model trained with PubMed.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The chemblId of the disease.", | |
| "required": true | |
| }, | |
| "threshold": { | |
| "type": "number", | |
| "description": "Threshold similarity between 0 and 1. Only results above threshold are returned.", | |
| "required": true | |
| }, | |
| "size": { | |
| "type": "integer", | |
| "description": "Number of similar entities to fetch.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query diseaseSimilarEntities($chemblId: String!, $threshold: Float!, $size: Int!) {\n drug(chemblId: $chemblId) {\n id\n name\n similarEntities(threshold: $threshold, size: $size) {\n id\n category\n score\n object {\n ... on Disease {\n id\n name\n }\n ... on Target {\n id\n approvedSymbol\n }\n ... on Drug {\n id\n name\n }\n }\n }\n }\n }\n ", | |
| "label": [ | |
| "Drug", | |
| "Similarity", | |
| "Model", | |
| "Entities", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_similar_entities_by_target_ensemblID", | |
| "description": "Retrieve similar entities for a given target ensemblID using a model trained with PubMed.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The ensemblID of the disease.", | |
| "required": true | |
| }, | |
| "threshold": { | |
| "type": "number", | |
| "description": "Threshold similarity between 0 and 1. Only results above threshold are returned.", | |
| "required": true | |
| }, | |
| "size": { | |
| "type": "integer", | |
| "description": "Number of similar entities to fetch.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query diseaseSimilarEntities($ensemblId: String!, $threshold: Float!, $size: Int!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n similarEntities(threshold: $threshold, size: $size) {\n id\n category\n score\n object {\n ... on Disease {\n id\n name\n }\n ... on Target {\n id\n approvedSymbol\n }\n ... on Drug {\n id\n name\n }\n }\n }\n }\n }\n ", | |
| "label": [ | |
| "Disease", | |
| "Similarity", | |
| "Model", | |
| "Entities", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_associated_phenotypes_by_disease_efoId", | |
| "description": "Find HPO phenotypes asosciated with the specified disease efoId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "efoId": { | |
| "type": "string", | |
| "description": "The efoId of a disease or phenotype.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "query diseaseAnnotation($efoId: String!) {\n disease(efoId: $efoId) {\n id\n name\n phenotypes {\n rows {\n phenotypeHPO {\n id\n name\n description\n namespace\n }\n phenotypeEFO {\n id\n name\n }\n }\n }\n }\n}", | |
| "label": [ | |
| "Disease", | |
| "OpenTarget", | |
| "GraphQL", | |
| "Phenotype", | |
| "Symptoms", | |
| "Clinical signs" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_drug_withdrawn_blackbox_status_by_chemblId", | |
| "description": "Find withdrawn and black-box warning statuses for a specific drug by chemblId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "array", | |
| "items": { | |
| "type": "string" | |
| }, | |
| "description": "The chemblId of a drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query drugWithdrawnWarningData($chemblId: String!) {\n drug(chemblId: $chemblId) {\n name\n id\n hasBeenWithdrawn\n blackBoxWarning\n }\n }\n ", | |
| "label": [ | |
| "Drug", | |
| "SafetyWarnings", | |
| "Withdrawal", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "search_category_counts_by_query_string", | |
| "description": "Get the count of entries in each entity category (disease, target, drug) based on a query string.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "queryString": { | |
| "type": "string", | |
| "description": "The search string for querying information.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query searchCategoryCounts($queryString: String!) {\n search(queryString: $queryString) {\n aggregations {\n total\n entities {\n total\n name\n }\n }\n }\n }\n ", | |
| "label": [ | |
| "OpenTarget", | |
| "GraphQL", | |
| "SearchResults", | |
| "Search", | |
| "Query", | |
| "Counts", | |
| "Categories" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_disease_id_description_by_name", | |
| "description": "Retrieve the efoId and additional details of a disease based on its name.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "diseaseName": { | |
| "type": "string", | |
| "description": "The name of the disease to search for.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query getDiseaseIdByName($diseaseName: String!) {\n search(queryString: $diseaseName, entityNames: [\"disease\"]) {\n hits {\n id\n name\n description\n }\n }\n }\n ", | |
| "label": [ | |
| "Disease", | |
| "Identification", | |
| "Search", | |
| "Name", | |
| "Disease", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_drug_id_description_by_name", | |
| "description": "Fetch the drug chemblId and description based on the drug name.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "drugName": { | |
| "type": "string", | |
| "description": "The name of the drug for which the ID is required.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query getDrugIdByName($drugName: String!) {\n search(queryString: $drugName, entityNames: [\"drug\"]) {\n hits {\n id\n name\n description\n }\n }\n }\n ", | |
| "label": [ | |
| "Identification", | |
| "Search", | |
| "Name", | |
| "Drug", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpentargetToolDrugNameMatch" | |
| }, | |
| { | |
| "name": "get_drug_indications_by_chemblId", | |
| "description": "Fetch indications (treatable phenotypes/diseases) for a given drug chemblId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The chemblId of the drug for which to retrieve treatable phenotypes information.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query drugIndications($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n indications {\n rows {\n disease {\n id\n name\n }\n maxPhaseForIndication\n references {\n source\n ids\n }\n }\n }\n }\n }\n ", | |
| "label": [ | |
| "Drug", | |
| "Indications", | |
| "Disease", | |
| "Treatment", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_gene_ontology_by_ensemblID", | |
| "description": "Retrieve Gene Ontology annotations for a specific target by Ensembl ID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target for which to retrieve Gene Ontology annotations.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query targetGeneOntology($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n geneOntology {\n aspect\n evidence\n geneProduct\n source\n term {\n id\n name\n }\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve the Gene Ontology annotations for the target with Ensembl ID 'ENSG00000136492'?", | |
| "query": { | |
| "name": "get_target_gene_ontology_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000136492" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the Gene Ontology annotations for the target identified by Ensembl ID 'ENSG00000138653'?", | |
| "query": { | |
| "name": "get_target_gene_ontology_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000138653" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please provide the Gene Ontology annotations for the target with Ensembl ID 'ENSG00000186162'.", | |
| "query": { | |
| "name": "get_target_gene_ontology_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000186162" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Target", | |
| "GeneOntology", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_homologues_by_ensemblID", | |
| "description": "Fetch homologues for a specific target by Ensembl ID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target for which to retrieve homologues.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query targetHomologues($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n homologues {\n homologyType\n queryPercentageIdentity\n speciesId\n speciesName\n targetGeneId\n targetGeneSymbol\n targetPercentageIdentity\n isHighConfidence\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you fetch homologues for the target with Ensembl ID 'ENSG00000100033'?", | |
| "query": { | |
| "name": "get_target_homologues_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000100033" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the homologues for the target identified by Ensembl ID 'ENSG00000288534'?", | |
| "query": { | |
| "name": "get_target_homologues_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000288534" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please provide the homologues for the target with Ensembl ID 'ENSG00000198937'.", | |
| "query": { | |
| "name": "get_target_homologues_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000198937" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "OpenTarget", | |
| "Target Information", | |
| "GraphQL", | |
| "Homologue" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_safety_profile_by_ensemblID", | |
| "description": "Retrieve known target safety liabilities for a specific target Ensembl ID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target for which to retrieve safety liabilities.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query targetSafetyLiabilities($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n safetyLiabilities {\n event\n eventId\n biosamples {\n cellFormat\n cellLabel\n tissueLabel\n tissueId\n }\n effects {\n dosing\n direction\n }\n studies {\n name\n type\n description\n }\n datasource\n literature\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you provide the safety liabilities for the target with Ensembl ID 'ENSG00000175274'?", | |
| "query": { | |
| "name": "target_safety_liabilities", | |
| "arguments": { | |
| "ensemblId": "ENSG00000175274" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the known safety effects for the target identified by Ensembl ID 'ENSG00000226446'?", | |
| "query": { | |
| "name": "target_safety_liabilities", | |
| "arguments": { | |
| "ensemblId": "ENSG00000226446" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please retrieve the safety risk information for the target with Ensembl ID 'ENSG00000151929'.", | |
| "query": { | |
| "name": "target_safety_liabilities", | |
| "arguments": { | |
| "ensemblId": "ENSG00000151929" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Target", | |
| "SafetyLiability", | |
| "OpenTarget", | |
| "GraphQL", | |
| "Safety", | |
| "Liabilities" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_biological_mouse_models_by_ensemblID", | |
| "description": "Retrieve biological mouse models, including allelic compositions and genetic backgrounds, for a specific target.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query fetchBiologicalModels($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n mousePhenotypes {\n biologicalModels {\n allelicComposition\n geneticBackground\n id\n literature\n }\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "What are the allelic compositions and genetic backgrounds for the target identified by Ensembl ID 'ENSG00000196639'?", | |
| "query": { | |
| "name": "get_biological_mouse_models_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000196639" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please provide the biological models for the target with the Ensembl ID 'ENSG00000171862'.", | |
| "query": { | |
| "name": "get_biological_mouse_models_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000171862" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "OpenTarget", | |
| "Target Information", | |
| "BiologicalModels", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_genomic_location_by_ensemblID", | |
| "description": "Retrieve genomic location data for a specific target, including chromosome, start, end, and strand.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target for which to retrieve genomic location information.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query targetGenomicLocation($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n genomicLocation {\n chromosome\n start\n end\n strand\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you provide the genomic location for the target with Ensembl ID 'ENSG00000114098'?", | |
| "query": { | |
| "name": "get_target_genomic_location_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000114098" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What is the genomic location data for the target identified by Ensembl ID 'ENSG00000231404'?", | |
| "query": { | |
| "name": "get_target_genomic_location_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000231404" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please retrieve the genomic location information for the target with Ensembl ID 'ENSG00000167258'.", | |
| "query": { | |
| "name": "get_target_genomic_location_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000167258" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Target", | |
| "GenomicLocation", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_subcellular_locations_by_ensemblID", | |
| "description": "Retrieve information about subcellular locations for a specific target ensemblID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The ensemblId of a target.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query targetSubcellularLocations($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n subcellularLocations {\n location\n source\n termSL\n labelSL\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you provide the subcellular locations for the target with Ensembl ID 'ENSG00000121898'?", | |
| "query": { | |
| "name": "get_target_subcellular_locations_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000121898" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the subcellular locations for the target identified by Ensembl ID 'ENSG00000274286'?", | |
| "query": { | |
| "name": "get_target_subcellular_locations_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000274286" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please retrieve the subcellular location information for the target with Ensembl ID 'ENSG00000171843'.", | |
| "query": { | |
| "name": "get_target_subcellular_locations_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000171843" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Target", | |
| "Subcellular Locations", | |
| "GraphQL", | |
| "OpenTarget" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_synonyms_by_ensemblID", | |
| "description": "Retrieve synonyms for specified target, including alternative names and symbols, using given ensemblID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query retrieveTargetSynonyms($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n synonyms {\n label\n source\n }\n symbolSynonyms {\n label\n source\n }\n nameSynonyms {\n label\n source\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve synonyms for the target with the Ensembl ID 'ENSG00000188986'?", | |
| "query": { | |
| "name": "get_target_synonyms_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000188986" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the alternative names and symbols for the target identified by Ensembl ID 'ENSG00000269335'?", | |
| "query": { | |
| "name": "get_target_synonyms_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000269335" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please provide the synonyms for the target with Ensembl ID 'ENSG00000141052'.", | |
| "query": { | |
| "name": "get_target_synonyms_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000141052" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "OpenTarget", | |
| "Target Information", | |
| "GraphQL", | |
| "Target" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_tractability_by_ensemblID", | |
| "description": "Retrieve tractability assessments, including modality and values, for a specific target ensembl ID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query targetTractabilityAssessment($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n tractability {\n label\n modality\n value\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve the tractability assessment for the target with Ensembl ID 'ENSG00000141736'?", | |
| "query": { | |
| "name": "get_target_tractability_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000141736" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the tractability assessments for the target identified by Ensembl ID 'ENSG00000169249'?", | |
| "query": { | |
| "name": "get_target_tractability_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000169249" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please provide the tractability assessment details for the target with Ensembl ID 'ENSG00000122548'.", | |
| "query": { | |
| "name": "get_target_tractability_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000122548" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Target", | |
| "Tractability", | |
| "OpenTarget", | |
| "Target Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_classes_by_ensemblID", | |
| "description": "Retrieve the target classes associated with a specific target ensemblID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query fetchTargetClasses($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n targetClass {\n id\n label\n level\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve the target classes for the target with Ensembl ID 'ENSG00000185324'?", | |
| "query": { | |
| "name": "get_target_classes_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000185324" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the target classes associated with the Ensembl ID 'ENSG00000141646'?", | |
| "query": { | |
| "name": "get_target_classes_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000141646" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please provide the target classes for the target identified by Ensembl ID 'ENSG00000141736'.", | |
| "query": { | |
| "name": "get_target_classes_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000141736" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "OpenTarget", | |
| "Target Information", | |
| "GraphQL", | |
| "Target" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_enabling_packages_by_ensemblID", | |
| "description": "Retrieve the Target Enabling Packages (TEP) associated with a specific target ensemblID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query fetchTargetEnablingPackages($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n tep {\n name\n uri\n therapeuticArea\n description\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve the Target Enabling Packages for the target with Ensembl ID 'ENSG00000167258'?", | |
| "query": { | |
| "name": "get_target_enabling_packages_by_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000167258" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "OpenTarget", | |
| "Target Information", | |
| "GraphQL", | |
| "Target" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_interactions_by_ensemblID", | |
| "description": "Retrieve interaction data for a specific target ensemblID, including interaction partners and evidence.", | |
| "label": [ | |
| "Target", | |
| "Interaction", | |
| "Evidence", | |
| "GraphQL", | |
| "Pagination", | |
| "OpenTarget" | |
| ], | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target.", | |
| "required": true | |
| }, | |
| "page": { | |
| "type": "object", | |
| "properties": { | |
| "index": { | |
| "type": "integer", | |
| "description": "The index of the page to retrieve.", | |
| "required": true | |
| }, | |
| "size": { | |
| "type": "integer", | |
| "description": "The number of items per page.", | |
| "required": true | |
| } | |
| }, | |
| "description": "Pagination parameters.", | |
| "required": false | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query targetInteractions($ensemblId: String!, $page: Pagination!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n interactions(page: $page) {\n count\n rows {\n intA\n targetA {\n id\n approvedSymbol\n }\n intB\n targetB {\n id\n approvedSymbol\n }\n score\n sourceDatabase\n evidences {\n evidenceScore\n pubmedId\n interactionDetectionMethodShortName\n }\n }\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve interaction data for the target with Ensembl ID 'ENSG00000134508' from the source database 'BioGRID'?", | |
| "query": { | |
| "name": "target_interactions", | |
| "arguments": { | |
| "ensemblId": "ENSG00000134508", | |
| "page": { | |
| "index": 1, | |
| "size": 10 | |
| } | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the interaction partners and evidence for the target identified by Ensembl ID 'ENSG00000276601'?", | |
| "query": { | |
| "name": "target_interactions", | |
| "arguments": { | |
| "ensemblId": "ENSG00000276601", | |
| "page": { | |
| "index": 2, | |
| "size": 5 | |
| } | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please provide the interaction data for the target with Ensembl ID 'ENSG00000287061' on the first page with 20 items per page.", | |
| "query": { | |
| "name": "target_interactions", | |
| "arguments": { | |
| "ensemblId": "ENSG00000287061", | |
| "page": { | |
| "index": 1, | |
| "size": 20 | |
| } | |
| } | |
| } | |
| } | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_disease_ancestors_parents_by_efoId", | |
| "description": "Retrieve the disease ancestors and parents in the ontology using the disease EFO ID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "efoId": { | |
| "type": "string", | |
| "description": "The EFO ID of the disease.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query getDiseaseDetailsByEfoId($efoId: String!) {\n disease(efoId: $efoId) {\n id\n name\n ancestors\n parents {\n id\n name\n }\n }\n }\n ", | |
| "label": [ | |
| "OpenTarget", | |
| "Disease", | |
| "Disease Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_disease_descendants_children_by_efoId", | |
| "description": "Retrieve the disease descendants and children in the ontology using the disease EFO ID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "efoId": { | |
| "type": "string", | |
| "description": "The EFO ID of the disease.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query getDiseaseDetailsByEfoId($efoId: String!) {\n disease(efoId: $efoId) {\n id\n name\n descendants\n children {\n id\n name\n }\n }\n }\n", | |
| "label": [ | |
| "OpenTarget", | |
| "Disease", | |
| "Disease Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_disease_locations_by_efoId", | |
| "description": "Retrieve the disease's direct location and indirect location disease terms and IDs using the disease EFO ID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "efoId": { | |
| "type": "string", | |
| "description": "The EFO ID of the disease.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query getDiseaseDetailsByEfoId($efoId: String!) {\n disease(efoId: $efoId) {\n id\n name\n directLocationIds\n indirectLocationIds\n directLocations {\n id\n name\n }\n indirectLocations {\n id\n name\n }\n }\n }\n ", | |
| "label": [ | |
| "OpenTarget", | |
| "Disease", | |
| "Disease Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_disease_synonyms_by_efoId", | |
| "description": "Retrieve disease synonyms by its EFO ID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "efoId": { | |
| "type": "string", | |
| "description": "The EFO ID of the disease.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query getDiseaseDetailsByEfoId($efoId: String!) {\n disease(efoId: $efoId) {\n id\n name\n synonyms {\n relation\n terms\n }\n }\n }\n", | |
| "label": [ | |
| "OpenTarget", | |
| "Disease", | |
| "Disease Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_disease_description_by_efoId", | |
| "description": "Retrieve disease description, name, database cros references, obsolete terms, and whether it's a therapeutic area, all using the specified efoId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "efoId": { | |
| "type": "string", | |
| "description": "The EFO ID of the disease.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query getDiseaseDetailsByEfoId($efoId: String!) {\n disease(efoId: $efoId) {\n id\n name\n description\n dbXRefs\n obsoleteTerms\n isTherapeuticArea\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you provide detailed information about the disease with the EFO ID 'MONDO_0000030'?", | |
| "query": { | |
| "name": "get_disease_description_by_efoId", | |
| "arguments": { | |
| "efoId": "MONDO_0000030" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the details of the disease identified by the EFO ID 'EFO_0007468'?", | |
| "query": { | |
| "name": "get_disease_description_by_efoId", | |
| "arguments": { | |
| "efoId": "EFO_0007468" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please retrieve information about the disease with the EFO ID 'Orphanet_217563'.", | |
| "query": { | |
| "name": "get_disease_description_by_efoId", | |
| "arguments": { | |
| "efoId": "Orphanet_217563" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "OpenTarget", | |
| "Disease", | |
| "Disease Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_disease_therapeutic_areas_by_efoId", | |
| "description": "Retrieve the therapeutic areas associated with a specific disease efoId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "efoId": { | |
| "type": "string", | |
| "description": "The EFO ID of the disease.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query diseaseTherapeuticAreas($efoId: String!) {\n disease(efoId: $efoId) {\n id\n name\n therapeuticAreas {\n id\n name\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "What therapeutic areas are linked to the disease with the efoId 'MONDO_0016474'?", | |
| "query": { | |
| "name": "get_disease_therapeutic_areas_by_efoId", | |
| "arguments": { | |
| "efoId": "MONDO_0016474" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Can you provide the therapeutic areas associated with the disease identified by efoId 'Orphanet_2579'?", | |
| "query": { | |
| "name": "get_disease_therapeutic_areas_by_efoId", | |
| "arguments": { | |
| "efoId": "Orphanet_2579" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please list the therapeutic areas for the disease with the efoId 'MONDO_0000873'.", | |
| "query": { | |
| "name": "get_disease_therapeutic_areas_by_efoId", | |
| "arguments": { | |
| "efoId": "MONDO_0000873" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "OpenTarget", | |
| "Disease", | |
| "TherapeuticArea", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_drug_adverse_events_by_chemblId", | |
| "description": "Retrieve significant adverse events reported for a specific drug chemblId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| }, | |
| "page": { | |
| "type": "object", | |
| "properties": { | |
| "index": { | |
| "type": "integer", | |
| "description": "Index of the page to fetch, starting from 0.", | |
| "required": true | |
| }, | |
| "size": { | |
| "type": "integer", | |
| "description": "Number of entries per page.", | |
| "required": true | |
| } | |
| }, | |
| "description": "Pagination settings.", | |
| "required": false | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query drugAdverseEvents($chemblId: String!, $page: Pagination!) {\n drug(chemblId: $chemblId) {\n id\n name\n adverseEvents(page: $page) {\n count\n criticalValue\n rows {\n name\n meddraCode\n count\n logLR\n }\n }\n }\n }\n ", | |
| "label": [ | |
| "Drug", | |
| "AdverseEvents", | |
| "Safety", | |
| "Reporting", | |
| "Pagination", | |
| "OpenTarget", | |
| "GraphQL", | |
| "AdverseEvents" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_known_drugs_by_drug_chemblId", | |
| "description": "Get a list of known drugs and associated information using the specified chemblId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query retrieveMultipleDrugsInfo($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n knownDrugs {\n uniqueDrugs\n uniqueDiseases\n uniqueTargets\n count\n cursor\n rows {\n approvedSymbol\n approvedName\n label\n prefName\n drugType\n targetId\n diseaseId\n drugId\n phase\n mechanismOfAction\n status\n targetClass\n references {\n source\n ids\n urls\n }\n ctIds\n urls {\n url\n name\n }\n disease {\n id\n name\n }\n target {\n id\n approvedSymbol\n }\n drug {\n id\n name\n }\n }\n }\n }\n }\n ", | |
| "label": [ | |
| "OpenTarget", | |
| "Drug", | |
| "Drug Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_parent_child_molecules_by_drug_chembl_ID", | |
| "description": "Get parent and child molecules of specified drug chemblId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query retrieveMultipleDrugsInfo($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n parentMolecule {\n id\n name\n }\n childMolecules {\n id\n name\n }\n }\n }\n ", | |
| "label": [ | |
| "OpenTarget", | |
| "Drug", | |
| "Drug Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_approved_indications_by_drug_chemblId", | |
| "description": "Retrieve detailed information about multiple drugs using a list of ChEMBL IDs.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query retrieveMultipleDrugsInfo($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n approvedIndications\n }\n }\n ", | |
| "label": [ | |
| "OpenTarget", | |
| "Drug", | |
| "Drug Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_drug_description_by_chemblId", | |
| "description": "Get drug name, year of first approval, type, cross references, and max clinical trial phase based on specified chemblId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query retrieveMultipleDrugsInfo($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n yearOfFirstApproval\n drugType\n crossReferences {\n source\n reference\n }\n maximumClinicalTrialPhase\n }\n }\n ", | |
| "label": [ | |
| "OpenTarget", | |
| "Drug", | |
| "Drug Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_drug_synonyms_by_chemblId", | |
| "description": "Retrieve the synonyms associated with a specific drug chemblId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query drugSynonyms($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n synonyms\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you provide the synonyms for the drug with ChEMBL ID 'CHEMBL2021430'?", | |
| "query": { | |
| "name": "drug_synget_drug_synonyms_by_chemblIdonyms", | |
| "arguments": { | |
| "chemblId": "CHEMBL2021430" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the synonyms associated with the drug identified by ChEMBL ID 'CHEMBL295698'?", | |
| "query": { | |
| "name": "get_drug_synonyms_by_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL295698" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please list the synonyms for the drug that has the ChEMBL ID 'CHEMBL1084617'.", | |
| "query": { | |
| "name": "get_drug_synonyms_by_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL1084617" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "OpenTarget", | |
| "Drug Information", | |
| "Drug", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_drug_trade_names_by_chemblId", | |
| "description": "Retrieve the trade names associated with a specific drug chemblId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query drugTradeNames($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n tradeNames\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "What are the trade names for the drug with ChEMBL ID 'CHEMBL25'?", | |
| "query": { | |
| "name": "get_drug_trade_names_by_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL25" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Can you provide the trade names associated with the drug identified by ChEMBL ID 'CHEMBL1201613'?", | |
| "query": { | |
| "name": "get_drug_trade_names_by_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL1201613" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please list the trade names for the drug that has the ChEMBL ID 'CHEMBL3182621'.", | |
| "query": { | |
| "name": "get_drug_trade_names_by_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL3182621" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Drug", | |
| "OpenTarget", | |
| "Drug Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_drug_approval_status_by_chemblId", | |
| "description": "Retrieve the approval status of a specific drug chemblId.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query drugApprovalStatus($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n isApproved\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "What is the approval status of the drug with ChEMBL ID 'CHEMBL2103799'?", | |
| "query": { | |
| "name": "get_drug_approval_status_by_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL2103799" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Can you tell me if the drug identified by ChEMBL ID 'CHEMBL1684' is approved?", | |
| "query": { | |
| "name": "get_drug_approval_status_by_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL1684" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please provide the approval status for the drug with ChEMBL ID 'CHEMBL1086997'.", | |
| "query": { | |
| "name": "get_drug_approval_status_by_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL1086997" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Drug", | |
| "Drug Information", | |
| "GraphQL", | |
| "OpenTarget" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_chemical_probes_by_target_ensemblID", | |
| "description": "Retrieve chemical probes associated with a specific target using its ensemblID.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target for which to retrieve chemical probes.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query getTargetChemicalProbes($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n chemicalProbes {\n id\n control\n drugId\n mechanismOfAction\n isHighQuality\n origin\n probeMinerScore\n probesDrugsScore\n scoreInCells\n scoreInOrganisms\n targetFromSourceId\n urls {\n niceName\n url\n }\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve the chemical probes for the target with Ensembl ID 'ENSG00000163515'?", | |
| "query": { | |
| "name": "get_chemical_probes_by_target_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000163515" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What chemical probes are associated with the target identified by Ensembl ID 'ENSG00000157916'?", | |
| "query": { | |
| "name": "get_chemical_probes_by_target_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000157916" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please list the chemical probes linked to the target with Ensembl ID 'ENSG00000253563'.", | |
| "query": { | |
| "name": "get_chemical_probes_by_target_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000253563" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "OpenTarget", | |
| "Drug Information", | |
| "ChemicalProbe", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "drug_pharmacogenomics_data", | |
| "description": "Retrieve pharmacogenomics data for a specific drug, including evidence levels and genotype annotations.", | |
| "label": [ | |
| "Drug", | |
| "Pharmacogenomics", | |
| "Evidence", | |
| "Genotype", | |
| "Pagination", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| }, | |
| "page": { | |
| "type": "object", | |
| "description": "Pagination options.", | |
| "properties": { | |
| "index": { | |
| "type": "integer", | |
| "description": "Pagination index.", | |
| "required": true | |
| }, | |
| "size": { | |
| "type": "integer", | |
| "description": "Number of records to fetch per page.", | |
| "required": true | |
| } | |
| }, | |
| "required": false | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query drugPharmacogenomicsData($chemblId: String!, $page: Pagination!) {\n drug(chemblId: $chemblId) {\n id\n name\n pharmacogenomics(page: $page) {\n datasourceId\n datatypeId\n genotype\n evidenceLevel\n genotypeAnnotationText\n genotypeId\n haplotypeFromSourceId\n haplotypeId\n literature\n pgxCategory\n phenotypeFromSourceId\n phenotypeText\n studyId\n targetFromSourceId\n variantFunctionalConsequenceId\n variantRsId\n isDirectTarget\n variantFunctionalConsequence {\n id\n label\n }\n drugs {\n drugId\n drug {\n name\n }\n }\n target {\n id\n approvedSymbol\n }\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you provide the pharmacogenomics data for the drug with ChEMBL ID 'CHEMBL23261'?", | |
| "query": { | |
| "name": "drug_pharmacogenomics_data", | |
| "arguments": { | |
| "chemblId": "CHEMBL23261", | |
| "page": { | |
| "index": 1, | |
| "size": 10 | |
| } | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the genotype annotations and evidence levels for the drug identified by ChEMBL ID 'CHEMBL1497'?", | |
| "query": { | |
| "name": "drug_pharmacogenomics_data", | |
| "arguments": { | |
| "chemblId": "CHEMBL1497", | |
| "page": { | |
| "index": 2, | |
| "size": 5 | |
| } | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Retrieve the pharmacogenomics data for the drug with ChEMBL ID 'CHEMBL4455124', including evidence levels.", | |
| "query": { | |
| "name": "drug_pharmacogenomics_data", | |
| "arguments": { | |
| "chemblId": "CHEMBL4455124", | |
| "page": { | |
| "index": 3, | |
| "size": 15 | |
| } | |
| } | |
| } | |
| } | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_associated_drugs_by_target_ensemblID", | |
| "description": "Get known drugs associated with a specific target ensemblID, including clinical trial phase and mechanism of action of the drugs.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target.", | |
| "required": true | |
| }, | |
| "size": { | |
| "type": "integer", | |
| "description": "Number of entries to fetch.", | |
| "required": true | |
| }, | |
| "cursor": { | |
| "type": "string", | |
| "description": "Cursor for pagination.", | |
| "required": false | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query targetKnownDrugs($ensemblId: String!, $size: Int!, $cursor: String) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n knownDrugs(size: $size, cursor: $cursor) {\n count\n rows {\n drug {\n id\n name\n tradeNames\n maximumClinicalTrialPhase\n isApproved\n hasBeenWithdrawn\n }\n phase\n status\n mechanismOfAction\n disease {\n id\n name\n }\n }\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve known drugs associated with the target having Ensembl ID 'ENSG00000141736' and fetch 10 entries?", | |
| "query": { | |
| "name": "get_associated_drugs_by_target_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000141736", | |
| "size": 10 | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the known drugs for the target with Ensembl ID 'ENSG00000184182', and can you provide 5 entries?", | |
| "query": { | |
| "name": "get_associated_drugs_by_target_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000184182", | |
| "size": 5 | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please list the known drugs associated with the target identified by Ensembl ID 'ENSG00000104884', and fetch 15 entries. Use the cursor 'abc123' for pagination.", | |
| "query": { | |
| "name": "get_associated_drugs_by_target_ensemblID", | |
| "arguments": { | |
| "ensemblId": "ENSG00000104884", | |
| "size": 15, | |
| "cursor": "abc123" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Target", | |
| "Drug", | |
| "MechanismsOfAction", | |
| "Pagination", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_associated_diseases_by_drug_chemblId", | |
| "description": "Retrieve the list of diseases associated with a specific drug chemblId based on clinical trial data or post-marketed drugs.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query fetchLinkedDiseasesForDrug($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n linkedDiseases {\n count\n rows {\n id\n name\n description\n }\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve the list of diseases linked to the drug with ChEMBL ID 'CHEMBL3137349'?", | |
| "query": { | |
| "name": "get_associated_diseases_by_drug_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL3137349" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What diseases are associated with the drug identified by ChEMBL ID 'CHEMBL1389'?", | |
| "query": { | |
| "name": "get_associated_diseases_by_drug_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL1389" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please provide the diseases linked to the drug that has the ChEMBL ID 'CHEMBL2109266'.", | |
| "query": { | |
| "name": "get_associated_diseases_by_drug_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL2109266" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Drug", | |
| "Disease", | |
| "OpenTarget", | |
| "Drug Information", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_associated_targets_by_drug_chemblId", | |
| "description": "Retrieve the list of targets linked to a specific drug chemblId based on its mechanism of action.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "chemblId": { | |
| "type": "string", | |
| "description": "The ChEMBL ID of the drug.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query fetchLinkedTargetsForDrug($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n name\n linkedTargets {\n count\n rows {\n id\n approvedSymbol\n approvedName\n }\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve the list of targets linked to the drug with ChEMBL ID 'CHEMBL459008'?", | |
| "query": { | |
| "name": "get_associated_targets_by_drug_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL459008" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the targets associated with the drug identified by ChEMBL ID 'CHEMBL1800955'?", | |
| "query": { | |
| "name": "get_associated_targets_by_drug_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL1800955" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please provide the list of targets for the drug with ChEMBL ID 'CHEMBL32'.", | |
| "query": { | |
| "name": "get_associated_targets_by_drug_chemblId", | |
| "arguments": { | |
| "chemblId": "CHEMBL32" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Drug", | |
| "Target", | |
| "MechanismsOfAction", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "multi_entity_search_by_query_string", | |
| "description": "Perform a multi-entity search based on a query string, filtering by entity names and pagination settings.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "queryString": { | |
| "type": "string", | |
| "description": "The search string for querying information.", | |
| "required": true | |
| }, | |
| "entityNames": { | |
| "type": "array", | |
| "items": { | |
| "type": "string" | |
| }, | |
| "description": "List of entity names to search for (e.g., target, disease, drug).", | |
| "required": false | |
| }, | |
| "page": { | |
| "type": "object", | |
| "properties": { | |
| "index": { | |
| "type": "integer", | |
| "description": "Pagination index.", | |
| "required": "True" | |
| }, | |
| "size": { | |
| "type": "integer", | |
| "description": "Pagination size.", | |
| "required": "True" | |
| } | |
| }, | |
| "description": "Pagination settings with index and size.", | |
| "required": false | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query multiEntitySearch($queryString: String!, $entityNames: [String!], $page: Pagination) {\n search(queryString: $queryString, entityNames: $entityNames, page: $page) {\n total\n hits {\n id\n entity\n description\n name\n score\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you search for information on the drug 'Aspirin' and the disease 'Hypertension'?", | |
| "query": { | |
| "name": "multi_entity_search_by_query_string", | |
| "arguments": { | |
| "queryString": "Aspirin Hypertension", | |
| "entityNames": [ | |
| "drug", | |
| "disease" | |
| ], | |
| "page": { | |
| "index": 1, | |
| "size": 10 | |
| } | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please find details about the target 'BRCA1' with pagination settings of index 2 and size 5.", | |
| "query": { | |
| "name": "multi_entity_search_by_query_string", | |
| "arguments": { | |
| "queryString": "BRCA1", | |
| "entityNames": [ | |
| "target" | |
| ], | |
| "page": { | |
| "index": 2, | |
| "size": 5 | |
| } | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What information is available for the disease 'Diabetes'?", | |
| "query": { | |
| "name": "multi_entity_search_by_query_string", | |
| "arguments": { | |
| "queryString": "Diabetes", | |
| "entityNames": [ | |
| "disease" | |
| ] | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Search and Mapping Functions", | |
| "MultiEntitySearch", | |
| "Pagination", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_gene_ontology_terms_by_goID", | |
| "description": "Retrieve Gene Ontology terms based on a list of GO IDs.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "goIds": { | |
| "type": "array", | |
| "items": { | |
| "type": "string" | |
| }, | |
| "description": "A list of Gene Ontology (GO) IDs to fetch the corresponding terms.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query fetchGeneOntologyTerms($goIds: [String!]!) {\n geneOntologyTerms(goIds: $goIds) {\n id\n name\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve the Gene Ontology terms for the GO IDs 'GO:0008150' and 'GO:0003674'?", | |
| "query": { | |
| "name": "fetch_gene_ontology_terms", | |
| "arguments": { | |
| "goIds": [ | |
| "GO:0008150", | |
| "GO:0003674" | |
| ] | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the Gene Ontology terms associated with the GO IDs 'GO:0005575', 'GO:0003674', and 'GO:0008150'?", | |
| "query": { | |
| "name": "fetch_gene_ontology_terms", | |
| "arguments": { | |
| "goIds": [ | |
| "GO:0005575", | |
| "GO:0003674", | |
| "GO:0008150" | |
| ] | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please provide the Gene Ontology terms for the following GO IDs: 'GO:0008150', 'GO:0003674', 'GO:0005575', and 'GO:0003677'.", | |
| "query": { | |
| "name": "fetch_gene_ontology_terms", | |
| "arguments": { | |
| "goIds": [ | |
| "GO:0008150", | |
| "GO:0003674", | |
| "GO:0005575", | |
| "GO:0003677" | |
| ] | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "GeneOntology", | |
| "Data Retrieval and Aggregation", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_constraint_info_by_ensemblID", | |
| "description": "Retrieve genetic constraint information for a specific target ensemblID, including expected and observed values, and scores.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "ensemblId": { | |
| "type": "string", | |
| "description": "The Ensembl ID of the target.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query targetConstraintInfo($ensemblId: String!) {\n target(ensemblId: $ensemblId) {\n id\n approvedSymbol\n geneticConstraint {\n constraintType\n exp\n obs\n oe\n oeLower\n oeUpper\n score\n upperBin\n upperBin6\n upperRank\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you provide the genetic constraint information for the target with Ensembl ID 'ENSG00000135476'?", | |
| "query": { | |
| "name": "target_constraint_info", | |
| "arguments": { | |
| "ensemblId": "ENSG00000135476" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "What are the expected and observed values, and scores for the target identified by Ensembl ID 'ENSG00000290763'?", | |
| "query": { | |
| "name": "target_constraint_info", | |
| "arguments": { | |
| "ensemblId": "ENSG00000290763" | |
| } | |
| } | |
| }, | |
| { | |
| "question": "Please retrieve the genetic constraint details for the target with Ensembl ID 'ENSG00000109906'.", | |
| "query": { | |
| "name": "target_constraint_info", | |
| "arguments": { | |
| "ensemblId": "ENSG00000109906" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Target", | |
| "Constraint", | |
| "Data Retrieval and Aggregation", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_publications_by_disease_efoId", | |
| "description": "Retrieve publications related to a disease efoId, including PubMed IDs and publication dates.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "entityId": { | |
| "type": "string", | |
| "description": "The ID of the entity (efoId).", | |
| "required": true | |
| }, | |
| "additionalIds": { | |
| "type": "array", | |
| "items": { | |
| "type": "string" | |
| }, | |
| "description": "List of additional IDs to include in the search.", | |
| "required": false | |
| }, | |
| "startYear": { | |
| "type": "integer", | |
| "description": "Year at the lower end of the filter.", | |
| "required": false | |
| }, | |
| "startMonth": { | |
| "type": "integer", | |
| "description": "Month at the lower end of the filter.", | |
| "required": false | |
| }, | |
| "endYear": { | |
| "type": "integer", | |
| "description": "Year at the higher end of the filter.", | |
| "required": false | |
| }, | |
| "endMonth": { | |
| "type": "integer", | |
| "description": "Month at the higher end of the filter.", | |
| "required": false | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query entityPublications($entityId: String!, $additionalIds: [String!], $startYear: Int, $startMonth: Int, $endYear: Int, $endMonth: Int) {\n disease(efoId: $entityId) {\n id\n name\n literatureOcurrences(additionalIds: $additionalIds, startYear: $startYear, startMonth: $startMonth, endYear: $endYear, endMonth: $endMonth) {\n count\n filteredCount\n earliestPubYear\n rows {\n pmid\n pmcid\n publicationDate\n sentences {\n section\n matches {\n mappedId\n matchedLabel\n sectionStart\n sectionEnd\n startInSentence\n endInSentence\n matchedType\n }\n }\n }\n }\n }\n }\n ", | |
| "examples": [ | |
| { | |
| "question": "Can you retrieve publications related to the entity with ID 'EFO_0000400'?", | |
| "query": { | |
| "name": "get_publications_by_disease_efoId", | |
| "arguments": { | |
| "entityId": "EFO_0000400" | |
| } | |
| } | |
| } | |
| ], | |
| "label": [ | |
| "Publications", | |
| "Data Retrieval and Aggregation", | |
| "GraphQL", | |
| "OpenTarget" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_publications_by_target_ensemblID", | |
| "description": "Retrieve publications related to a target ensemblID, including PubMed IDs and publication dates.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "entityId": { | |
| "type": "string", | |
| "description": "The ID of the entity (ensemblID).", | |
| "required": true | |
| }, | |
| "additionalIds": { | |
| "type": "array", | |
| "items": { | |
| "type": "string" | |
| }, | |
| "description": "List of additional IDs to include in the search.", | |
| "required": false | |
| }, | |
| "startYear": { | |
| "type": "integer", | |
| "description": "Year at the lower end of the filter.", | |
| "required": false | |
| }, | |
| "startMonth": { | |
| "type": "integer", | |
| "description": "Month at the lower end of the filter.", | |
| "required": false | |
| }, | |
| "endYear": { | |
| "type": "integer", | |
| "description": "Year at the higher end of the filter.", | |
| "required": false | |
| }, | |
| "endMonth": { | |
| "type": "integer", | |
| "description": "Month at the higher end of the filter.", | |
| "required": false | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query entityPublications($entityId: String!, $additionalIds: [String!], $startYear: Int, $startMonth: Int, $endYear: Int, $endMonth: Int) {\n target(ensemblId: $entityId) {\n id\n approvedSymbol\n literatureOcurrences(additionalIds: $additionalIds, startYear: $startYear, startMonth: $startMonth, endYear: $endYear, endMonth: $endMonth) {\n count\n filteredCount\n earliestPubYear\n rows {\n pmid\n pmcid\n publicationDate\n sentences {\n section\n matches {\n mappedId\n matchedLabel\n sectionStart\n sectionEnd\n startInSentence\n endInSentence\n matchedType\n }\n }\n }\n }\n }\n }\n ", | |
| "label": [ | |
| "Publications", | |
| "Data Retrieval and Aggregation", | |
| "GraphQL", | |
| "OpenTarget" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_publications_by_drug_chemblId", | |
| "description": "Retrieve publications related to a drug chemblId, including PubMed IDs and publication dates.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "entityId": { | |
| "type": "string", | |
| "description": "The ID of the entity (chemblId).", | |
| "required": true | |
| }, | |
| "additionalIds": { | |
| "type": "array", | |
| "items": { | |
| "type": "string" | |
| }, | |
| "description": "List of additional IDs to include in the search.", | |
| "required": false | |
| }, | |
| "startYear": { | |
| "type": "integer", | |
| "description": "Year at the lower end of the filter.", | |
| "required": false | |
| }, | |
| "startMonth": { | |
| "type": "integer", | |
| "description": "Month at the lower end of the filter.", | |
| "required": false | |
| }, | |
| "endYear": { | |
| "type": "integer", | |
| "description": "Year at the higher end of the filter.", | |
| "required": false | |
| }, | |
| "endMonth": { | |
| "type": "integer", | |
| "description": "Month at the higher end of the filter.", | |
| "required": false | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query entityPublications($entityId: String!, $additionalIds: [String!], $startYear: Int, $startMonth: Int, $endYear: Int, $endMonth: Int) {\n drug(chemblId: $entityId) {\n id\n name\n literatureOcurrences(additionalIds: $additionalIds, startYear: $startYear, startMonth: $startMonth, endYear: $endYear, endMonth: $endMonth) {\n count\n filteredCount\n earliestPubYear\n rows {\n pmid\n pmcid\n publicationDate\n sentences {\n section\n matches {\n mappedId\n matchedLabel\n sectionStart\n sectionEnd\n startInSentence\n endInSentence\n matchedType\n }\n }\n }\n }\n }\n }\n ", | |
| "label": [ | |
| "Publications", | |
| "Data Retrieval and Aggregation", | |
| "GraphQL", | |
| "OpenTarget" | |
| ], | |
| "type": "OpenTarget" | |
| }, | |
| { | |
| "name": "get_target_id_description_by_name", | |
| "description": "Get the ensemblId and description based on the target name.", | |
| "parameter": { | |
| "type": "object", | |
| "properties": { | |
| "targetName": { | |
| "type": "string", | |
| "description": "The name of the target for which the ID is required.", | |
| "required": true | |
| } | |
| } | |
| }, | |
| "query_schema": "\n query getTargetIdByName($targetName: String!) {\n search(queryString: $targetName, entityNames: [\"target\"]) {\n hits {\n id\n name\n description\n }\n }\n }\n ", | |
| "label": [ | |
| "Search", | |
| "Name", | |
| "Target", | |
| "OpenTarget", | |
| "GraphQL" | |
| ], | |
| "type": "OpenTarget" | |
| } | |
| ] |