fixed the bug

app.py

@@ -161,8 +161,6 @@ with gr.Blocks(theme=gr.themes.Soft()) as demo:
              100]
         ],
         inputs=[protein_sequence, num_samples],
-        outputs=output_smiles,
-        fn=generate_smiles_for_sequence,
         cache_examples=False,
     )
 
@@ -172,7 +170,7 @@ with gr.Blocks(theme=gr.themes.Soft()) as demo:
         *Model developed by Gero AI. For more details, check out the [original repository](https://github.com/gero-science/ProtoBind-Diff).*
         """
     )
-    protein_sequence.input(enable_btn, inputs=protein_sequence, outputs=submit_btn)
+    protein_sequence.change(enable_btn, inputs=protein_sequence, outputs=submit_btn)
 
     submit_btn.click(
         fn=generate_smiles_for_sequence,