Update app.py

app.py

@@ -497,3 +497,59 @@ async def download_section(job_id: str, section: str):
     return StreamingResponse(io.BytesIO(gz),
                              media_type="application/gzip",
                              headers={"Content-Disposition": f'attachment; filename="{job_id}_{section}.json.gz"'} )
+
+@app.get("/selfcheck")
+async def selfcheck(
+    receptor: str = Query("bupropion"),
+    symptom: str = Query("anhedonia")
+):
+    """
+    Runs the same checks your GPT does:
+      - /health
+      - /mechanism_graph_manifest
+      - /heuristics/regions_from_string
+    Returns a compact PASS/FAIL summary in one JSON.
+    """
+    out = {"input": {"receptor": receptor, "symptom": symptom}}
+
+    # health
+    try:
+        out["health"] = {"ok": True, "data": health()}
+    except Exception as e:
+        out["health"] = {"ok": False, "error": str(e)}
+
+    # manifest
+    try:
+        mani = await mechanism_graph_manifest(
+            receptor=receptor, symptom=symptom,
+            species=9606, string_limit=50, lit_page_size=10
+        )
+        out["manifest"] = {
+            "ok": True,
+            "job_id": mani.get("job_id"),
+            "sections": mani.get("sections", [])
+        }
+    except Exception as e:
+        out["manifest"] = {"ok": False, "error": str(e)}
+
+    # regions (robust to drugs)
+    try:
+        reg = await regions_from_string(
+            receptor=receptor, species=9606,
+            limit=25, regions=None, use_synonyms=True, symptom=None
+        )
+        out["regions"] = {
+            "ok": True,
+            "count": len(reg.get("regions_ranked", [])),
+            "sample": reg.get("regions_ranked", [])[:5]
+        }
+    except Exception as e:
+        out["regions"] = {"ok": False, "error": str(e)}
+
+    # overall
+    out["overall_ok"] = all([
+        out["health"].get("ok"),
+        out["manifest"].get("ok"),
+        out["regions"].get("ok"),
+    ])
+    return out