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dmsaylor commited on
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44fe5af
·
1 Parent(s): 345b471

added impurity evaluation for non-CA additives

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Files changed (4) hide show
  1. color_module/colors.py +1 -0
  2. color_module/templates/index.html +1 -1
  3. color_module/templates/report.html +8 -9
  4. static/Changelog.md +4 -0
color_module/colors.py CHANGED
@@ -79,6 +79,7 @@ def app_post():
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  MW = float(request.form["MW"])
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  chemName = request.form["chemName"] if "chemName" in request.form else "CHEMICAL NAME NOT PROVIDED"
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  chemName = '*' + chemName + '*'
 
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  if exposure != "limited":
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  time = 24.
 
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  MW = float(request.form["MW"])
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  chemName = request.form["chemName"] if "chemName" in request.form else "CHEMICAL NAME NOT PROVIDED"
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  chemName = '*' + chemName + '*'
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+ impurity = float(request.form["impurity"]) * amount * 1e-2
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  if exposure != "limited":
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  time = 24.
color_module/templates/index.html CHANGED
@@ -56,7 +56,7 @@ function caCheck() {
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  document.getElementById('impurity').disabled = false;
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  if (iCA >= 13) {
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- document.getElementById('impurity').disabled = true;
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  }
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  if (iCA >= 12) {
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  document.getElementById('MW').disabled = false;
 
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  document.getElementById('impurity').disabled = false;
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  if (iCA >= 13) {
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+ // document.getElementById('impurity').disabled = true;
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  }
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  if (iCA >= 12) {
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  document.getElementById('MW').disabled = false;
color_module/templates/report.html CHANGED
@@ -16,7 +16,7 @@
16
 
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  <body>
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- <p> The following report was generated using CHRIS v.1.1.1 on
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  <script> document.write(new Date().toLocaleDateString()); </script>.
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  </p>
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@@ -164,13 +164,11 @@ of {{MOS}}.
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  {% endif %}
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- {% if isCA == true %}
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-
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- <h3> Color additive impurities </h3>
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  {% if iMOS >= 1 %}
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- <font color="green"> The total color additive impurity level is {{impurity}} mg. When compared to TTC this results in
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  an MOS = {{iMOS}}. Therefore, no further analysis is needed for the impact of impurities on systemic
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  biocompatibility endpoints. </font>
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@@ -178,22 +176,23 @@ of {{MOS}}.
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  <font color="red"> *Note*: This assessment assumes that any impurities present are not in the cohort of concern. </font>
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  </p>
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  <p>
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  <font color="red"> *Note*: Users should review and confirm compliance of impurity levels with any relevant Code of
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  Federal Regulations (CFR) listings as part of the submission package, i.e. in addition to any output of CHRIS.
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  A list of relevant CFR listings is provided
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  <a href="color_module/FAQ.html#how-does-chris-deal-with-color-additive-impurities" >here</a>.</font>
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  </p>
 
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  {% else %}
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- <font color="red"> The total color additive impurity level is {{impurity}} mg. When compared to TTC this results in
 
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  an MOS = {{iMOS}}. Therefore, further analysis is needed to address the impact of impurities on systemic
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  biocompatibility endpoints. Guidance on alternative methods to address impurities is provided
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  <a href="color_module/FAQ.html#how-does-chris-deal-with-color-additive-impurities" >here</a>. </font>
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-
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-
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- {% endif %}
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  {% endif %}
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  <body>
18
 
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+ <p> The following report was generated using CHRIS v.1.1.2 on
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  <script> document.write(new Date().toLocaleDateString()); </script>.
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  </p>
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  {% endif %}
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+ <h3> Impurities </h3>
 
 
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  {% if iMOS >= 1 %}
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+ <font color="green"> The total additive impurity level is {{impurity}} mg. When compared to TTC this results in
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  an MOS = {{iMOS}}. Therefore, no further analysis is needed for the impact of impurities on systemic
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  biocompatibility endpoints. </font>
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  <font color="red"> *Note*: This assessment assumes that any impurities present are not in the cohort of concern. </font>
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  </p>
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+ {% if isCA == true %}
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  <p>
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  <font color="red"> *Note*: Users should review and confirm compliance of impurity levels with any relevant Code of
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  Federal Regulations (CFR) listings as part of the submission package, i.e. in addition to any output of CHRIS.
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  A list of relevant CFR listings is provided
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  <a href="color_module/FAQ.html#how-does-chris-deal-with-color-additive-impurities" >here</a>.</font>
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  </p>
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+ {% endif %}
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  {% else %}
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+ <p>
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+ <font color="red"> The total additive impurity level is {{impurity}} mg. When compared to TTC this results in
192
  an MOS = {{iMOS}}. Therefore, further analysis is needed to address the impact of impurities on systemic
193
  biocompatibility endpoints. Guidance on alternative methods to address impurities is provided
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  <a href="color_module/FAQ.html#how-does-chris-deal-with-color-additive-impurities" >here</a>. </font>
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+ </p>
 
 
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  {% endif %}
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static/Changelog.md CHANGED
@@ -14,6 +14,10 @@
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  ```
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  ## Change Log
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  ### Version 1.1.1 - 2022-12-07
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  * Modified header of the landing page
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  * Added contact information for suggested improvements
 
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  ```
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  ## Change Log
16
 
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+ ### Version 1.1.2 - 2022-12-07
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+ * Added impurity evaluation for non-CA additives
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+ * Fixed typos
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+
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  ### Version 1.1.1 - 2022-12-07
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  * Modified header of the landing page
23
  * Added contact information for suggested improvements