| TCGA_PARAMS = { |
| "immune_hot": { |
| "inspired_by": "Skin Cutaneous Melanoma (SKCM), n=440", |
| "tmb": {"dist": "lognormal", "mean_log": 2.5998, "std_log": 1.2026}, |
| "genomic_instability": {"dist": "normal", "mean": 0.3218, "std": 0.2100}, |
| "mutation_count": {"dist": "lognormal", "mean_log": 5.9979, "std_log": 1.1969}, |
| }, |
| "immune_cold": { |
| "inspired_by": "Glioblastoma Multiforme (GBM), n=397", |
| "tmb": {"dist": "lognormal", "mean_log": 0.6189, "std_log": 0.7192}, |
| "genomic_instability": {"dist": "normal", "mean": 0.2071, "std": 0.1221}, |
| "mutation_count": {"dist": "lognormal", "mean_log": 4.0258, "std_log": 0.6904}, |
| }, |
| "high_mutation": { |
| "inspired_by": "Top 25% TMB cohort from SKCM, n=110", |
| "tmb": {"dist": "lognormal", "mean_log": 6.5080, "std_log": 0.8088}, |
| "genomic_instability": {"dist": "normal", "mean": 0.3218, "std": 0.2100}, |
| "mutation_count": {"dist": "lognormal", "mean_log": 4.0080, "std_log": 0.5068}, |
| }, |
| } |
|
|
