File size: 27,271 Bytes
35afe56 | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499 500 501 502 503 504 505 506 507 508 509 510 511 512 513 514 515 516 517 518 519 520 521 522 523 524 525 526 527 528 529 530 531 532 533 534 535 536 537 538 539 540 541 542 543 544 545 546 547 548 549 550 551 552 553 554 555 556 557 558 559 560 561 562 563 564 565 566 567 568 569 570 571 572 573 574 575 576 577 578 579 580 581 582 583 584 585 586 587 588 589 590 591 592 593 594 595 596 597 598 599 600 601 602 603 604 605 606 607 608 609 610 611 612 613 614 615 616 617 618 619 620 621 622 623 624 625 626 627 628 629 630 631 632 633 634 635 636 637 638 639 640 641 642 643 644 645 646 647 648 649 650 651 652 653 654 655 656 657 658 659 660 661 662 663 664 665 666 667 668 669 670 671 672 673 674 675 676 677 678 679 680 681 682 683 684 685 686 687 688 689 690 691 692 693 694 | <!DOCTYPE html>
<html lang="en">
<head>
<meta charset="UTF-8">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<title>D. melanogaster Batch 01: Development & Genetics - Programming Framework Analysis</title>
<script src="https://cdn.jsdelivr.net/npm/mermaid@10.6.1/dist/mermaid.min.js"></script>
<style>
body {
font-family: 'Segoe UI', Tahoma, Geneva, Verdana, 'Arial Unicode MS', sans-serif;
line-height: 1.6;
margin: 0;
padding: 0;
background: linear-gradient(135deg, #667eea 0%, #764ba2 100%);
min-height: 100vh;
}
.container {
max-width: 1400px;
margin: 0 auto;
background: white;
box-shadow: 0 0 20px rgba(0,0,0,0.1);
border-radius: 10px;
overflow: hidden;
}
.header {
background: linear-gradient(135deg, #667eea 0%, #764ba2 100%);
color: white;
padding: 2rem;
text-align: center;
}
.header h1 {
margin: 0;
font-size: 2.5rem;
font-weight: 300;
}
.content {
padding: 2rem;
}
.intro {
background: #f8f9fa;
padding: 2rem;
border-radius: 8px;
margin-bottom: 2rem;
}
.toc {
background: #f8f9fa;
padding: 2rem;
border-radius: 8px;
margin-bottom: 2rem;
}
.toc ul {
list-style: none;
padding: 0;
}
.toc li {
margin: 0.5rem 0;
}
.toc a {
color: #007bff;
text-decoration: none;
font-weight: 500;
}
.process-item {
margin: 2rem 0;
padding: 1.5rem;
border: 1px solid #dee2e6;
border-radius: 8px;
background: #fafafa;
}
.process-item h3 {
color: #495057;
margin-bottom: 1rem;
}
.mermaid-container {
background: white;
padding: 1rem;
border-radius: 8px;
margin: 1rem 0;
overflow-x: auto;
}
.footer {
background: #f8f9fa;
padding: 2rem;
text-align: center;
border-top: 1px solid #dee2e6;
margin-top: 2rem;
}
.color-legend {
display: grid;
grid-template-columns: repeat(auto-fit, minmax(140px, 1fr));
gap: 0.5rem 1rem;
margin: 1rem 0 0;
font-size: 10pt;
color: #333;
}
.color-box {
display: inline-block;
width: 12px;
height: 12px;
border-radius: 2px;
margin-right: 4px;
border: 1px solid rgba(0,0,0,.15);
}
</style>
</head>
<body>
<div class="container">
<div class="header">
<h1>🦟 D. melanogaster Batch 01: Development & Genetics</h1>
<p>Programming Framework Analysis - 8 Eukaryotic Processes</p>
</div>
<div class="content">
<div class="intro">
<h2>🦟 Development & Genetics Systems</h2>
<p><strong>Batch Overview:</strong> This batch contains 8 fundamental D. melanogaster processes responsible for development and genetics. These processes represent the core computational systems that enable this model organism to develop from embryo to adult, exhibit complex behaviors, and maintain genetic integrity.</p>
<p>Each process demonstrates sophisticated biological programming with developmental pathways, genetic regulation, neural circuits, and behavioral responses.</p>
</div>
<div class="toc">
<h2>📋 Table of Contents - 8 Eukaryotic Processes</h2>
<ul>
<li><a href="#embryonic-patterning">1. Embryonic Patterning</a></li>
<li><a href="#segmentation">2. Segmentation</a></li>
<li><a href="#homeotic-regulation">3. Homeotic Regulation</a></li>
<li><a href="#neural-development">4. Neural Development</a></li>
<li><a href="#behavioral-genetics">5. Behavioral Genetics</a></li>
<li><a href="#circadian-rhythms">6. Circadian Rhythms</a></li>
<li><a href="#learning-memory">7. Learning & Memory</a></li>
<li><a href="#genetic-regulation">8. Genetic Regulation</a></li>
</ul>
</div>
<!-- Process 1: Embryonic Patterning -->
<div class="process-item" id="embryonic-patterning">
<h3>1. Embryonic Patterning</h3>
<p>Detailed analysis of D. melanogaster Embryonic Patterning using the Programming Framework, revealing computational logic and regulatory patterns for early development.</p>
<div class="mermaid-container">
<div class="mermaid">
graph TD
%% Patterning Components
A[Maternal Factors] --> B[Anterior-Posterior Axis]
C[Dorsal-Ventral Axis] --> D[Polarity Establishment]
E[Gap Genes] --> F[Segment Polarity]
G[Pair-Rule Genes] --> H[Pattern Formation]
%% Maternal Control
B --> I[Bicoid mRNA]
I --> J[Nanos mRNA]
J --> K[Protein Gradients]
%% Axis Formation
D --> L[Toll Signaling]
L --> M[Dorsal Protein]
M --> N[D-V Patterning]
%% Gap Gene Expression
F --> O[Giant Expression]
O --> P[Krüppel Expression]
P --> Q[Segment Boundaries]
%% Integration
K --> R[Patterning Program]
N --> R
Q --> R
H --> R
R --> S[Embryonic Pattern]
%% Styling - Programming Framework Colors
style A fill:#ff6b6b,color:#fff
style C fill:#ff6b6b,color:#fff
style E fill:#ff6b6b,color:#fff
style G fill:#ff6b6b,color:#fff
style B fill:#ffd43b,color:#000
style D fill:#ffd43b,color:#000
style F fill:#ffd43b,color:#000
style H fill:#ffd43b,color:#000
style I fill:#ffd43b,color:#000
style J fill:#51cf66,color:#fff
style K fill:#51cf66,color:#fff
style L fill:#ffd43b,color:#000
style M fill:#51cf66,color:#fff
style N fill:#51cf66,color:#fff
style O fill:#ffd43b,color:#000
style P fill:#51cf66,color:#fff
style Q fill:#51cf66,color:#fff
style R fill:#74c0fc,color:#fff
style S fill:#b197fc,color:#fff
</div>
<div class="color-legend">
<span><span class="color-box" style="background:#ff6b6b;"></span>Triggers & Conditions</span>
<span><span class="color-box" style="background:#ffd43b;"></span>Catalysts & Enzymes</span>
<span><span class="color-box" style="background:#51cf66;"></span>Chemical Processing</span>
<span><span class="color-box" style="background:#74c0fc;"></span>Intermediates</span>
<span><span class="color-box" style="background:#b197fc;"></span>Products</span>
</div>
</div>
</div>
<!-- Process 2: Segmentation -->
<div class="process-item" id="segmentation">
<h3>2. Segmentation</h3>
<p>Detailed analysis of D. melanogaster Segmentation using the Programming Framework, revealing computational logic and regulatory patterns for body segment formation.</p>
<div class="mermaid-container">
<div class="mermaid">
graph TD
%% Segmentation Components
A[Gap Gene Expression] --> B[Pair-Rule Genes]
C[Segment Polarity] --> D[Engrailed Expression]
E[Wingless Signaling] --> F[Segment Boundaries]
G[Homeotic Genes] --> H[Segment Identity]
%% Pair-Rule Expression
B --> I[Even-Skipped]
I --> J[Fushi Tarazu]
J --> K[Segment Stripes]
%% Segment Polarity
D --> L[Engrailed/Wingless]
L --> M[Cell Communication]
M --> N[Segment Maintenance]
%% Segment Identity
F --> O[Antennapedia Complex]
O --> P[Bithorax Complex]
P --> Q[Segment Specification]
%% Integration
K --> R[Segmentation Program]
N --> R
Q --> R
H --> R
R --> S[Body Segmentation]
%% Styling - Programming Framework Colors
style A fill:#ff6b6b,color:#fff
style C fill:#ff6b6b,color:#fff
style E fill:#ff6b6b,color:#fff
style G fill:#ff6b6b,color:#fff
style B fill:#ffd43b,color:#000
style D fill:#ffd43b,color:#000
style F fill:#ffd43b,color:#000
style H fill:#ffd43b,color:#000
style I fill:#ffd43b,color:#000
style J fill:#51cf66,color:#fff
style K fill:#51cf66,color:#fff
style L fill:#ffd43b,color:#000
style M fill:#51cf66,color:#fff
style N fill:#51cf66,color:#fff
style O fill:#ffd43b,color:#000
style P fill:#51cf66,color:#fff
style Q fill:#51cf66,color:#fff
style R fill:#74c0fc,color:#fff
style S fill:#b197fc,color:#fff
</div>
<div class="color-legend">
<span><span class="color-box" style="background:#ff6b6b;"></span>Triggers & Conditions</span>
<span><span class="color-box" style="background:#ffd43b;"></span>Catalysts & Enzymes</span>
<span><span class="color-box" style="background:#51cf66;"></span>Chemical Processing</span>
<span><span class="color-box" style="background:#74c0fc;"></span>Intermediates</span>
<span><span class="color-box" style="background:#b197fc;"></span>Products</span>
</div>
</div>
</div>
<!-- Process 3: Homeotic Regulation -->
<div class="process-item" id="homeotic-regulation">
<h3>3. Homeotic Regulation</h3>
<p>Detailed analysis of D. melanogaster Homeotic Regulation using the Programming Framework, revealing computational logic and regulatory patterns for segment identity.</p>
<div class="mermaid-container">
<div class="mermaid">
graph TD
%% Homeotic Components
A[Homeotic Genes] --> B[Antennapedia Complex]
C[Bithorax Complex] --> D[Segment Identity]
E[Polycomb Group] --> F[Gene Silencing]
G[Trithorax Group] --> H[Gene Activation]
%% Antennapedia Complex
B --> I[Labial Expression]
I --> J[Proboscipedia]
J --> K[Deformed Expression]
%% Bithorax Complex
D --> L[Ultrabithorax]
L --> M[Abdominal-A]
M --> N[Abdominal-B]
%% Epigenetic Control
F --> O[Polycomb Repression]
O --> P[Chromatin Modification]
P --> Q[Gene Silencing]
%% Integration
K --> R[Homeotic Program]
N --> R
Q --> R
H --> R
R --> S[Segment Identity]
%% Styling - Programming Framework Colors
style A fill:#ff6b6b,color:#fff
style C fill:#ff6b6b,color:#fff
style E fill:#ff6b6b,color:#fff
style G fill:#ff6b6b,color:#fff
style B fill:#ffd43b,color:#000
style D fill:#ffd43b,color:#000
style F fill:#ffd43b,color:#000
style H fill:#ffd43b,color:#000
style I fill:#ffd43b,color:#000
style J fill:#51cf66,color:#fff
style K fill:#51cf66,color:#fff
style L fill:#ffd43b,color:#000
style M fill:#51cf66,color:#fff
style N fill:#51cf66,color:#fff
style O fill:#ffd43b,color:#000
style P fill:#51cf66,color:#fff
style Q fill:#51cf66,color:#fff
style R fill:#74c0fc,color:#fff
style S fill:#b197fc,color:#fff
</div>
<div class="color-legend">
<span><span class="color-box" style="background:#ff6b6b;"></span>Triggers & Conditions</span>
<span><span class="color-box" style="background:#ffd43b;"></span>Catalysts & Enzymes</span>
<span><span class="color-box" style="background:#51cf66;"></span>Chemical Processing</span>
<span><span class="color-box" style="background:#74c0fc;"></span>Intermediates</span>
<span><span class="color-box" style="background:#b197fc;"></span>Products</span>
</div>
</div>
</div>
<!-- Process 4: Neural Development -->
<div class="process-item" id="neural-development">
<h3>4. Neural Development</h3>
<p>Detailed analysis of D. melanogaster Neural Development using the Programming Framework, revealing computational logic and regulatory patterns for nervous system formation.</p>
<div class="mermaid-container">
<div class="mermaid">
graph TD
%% Neural Components
A[Neural Precursors] --> B[Neurogenesis]
C[Notch Signaling] --> D[Cell Fate Decision]
E[Axon Guidance] --> F[Neural Circuits]
G[Synapse Formation] --> H[Neural Function]
%% Neurogenesis
B --> I[Neural Progenitors]
I --> J[Neuron/Glia Decision]
J --> K[Neural Identity]
%% Notch Signaling
D --> L[Delta-Notch]
L --> M[Lateral Inhibition]
M --> N[Cell Fate Specification]
%% Axon Guidance
F --> O[Netrin Signaling]
O --> P[Slit/Robo]
P --> Q[Axon Pathfinding]
%% Integration
K --> R[Neural Program]
N --> R
Q --> R
H --> R
R --> S[Neural Circuit]
%% Styling - Programming Framework Colors
style A fill:#ff6b6b,color:#fff
style C fill:#ff6b6b,color:#fff
style E fill:#ff6b6b,color:#fff
style G fill:#ff6b6b,color:#fff
style B fill:#ffd43b,color:#000
style D fill:#ffd43b,color:#000
style F fill:#ffd43b,color:#000
style H fill:#ffd43b,color:#000
style I fill:#ffd43b,color:#000
style J fill:#51cf66,color:#fff
style K fill:#51cf66,color:#fff
style L fill:#ffd43b,color:#000
style M fill:#51cf66,color:#fff
style N fill:#51cf66,color:#fff
style O fill:#ffd43b,color:#000
style P fill:#51cf66,color:#fff
style Q fill:#51cf66,color:#fff
style R fill:#74c0fc,color:#fff
style S fill:#b197fc,color:#fff
</div>
<div class="color-legend">
<span><span class="color-box" style="background:#ff6b6b;"></span>Triggers & Conditions</span>
<span><span class="color-box" style="background:#ffd43b;"></span>Catalysts & Enzymes</span>
<span><span class="color-box" style="background:#51cf66;"></span>Chemical Processing</span>
<span><span class="color-box" style="background:#74c0fc;"></span>Intermediates</span>
<span><span class="color-box" style="background:#b197fc;"></span>Products</span>
</div>
</div>
</div>
<!-- Process 5: Behavioral Genetics -->
<div class="process-item" id="behavioral-genetics">
<h3>5. Behavioral Genetics</h3>
<p>Detailed analysis of D. melanogaster Behavioral Genetics using the Programming Framework, revealing computational logic and regulatory patterns for behavior generation.</p>
<div class="mermaid-container">
<div class="mermaid">
graph TD
%% Behavioral Components
A[Genetic Background] --> B[Behavioral Genes]
C[Neural Circuits] --> D[Behavioral Output]
E[Environmental Cues] --> F[Behavioral Response]
G[Learning Genes] --> H[Behavioral Plasticity]
%% Behavioral Genes
B --> I[Period Gene]
I --> J[Clock Genes]
J --> K[Circadian Behavior]
%% Neural Circuits
D --> L[Mushroom Bodies]
L --> M[Central Complex]
M --> N[Behavioral Control]
%% Learning Genes
F --> O[dunce Gene]
O --> P[rutabaga Gene]
P --> Q[Learning Ability]
%% Integration
K --> R[Behavioral Program]
N --> R
Q --> R
H --> R
R --> S[Behavioral Output]
%% Styling - Programming Framework Colors
style A fill:#ff6b6b,color:#fff
style C fill:#ff6b6b,color:#fff
style E fill:#ff6b6b,color:#fff
style G fill:#ff6b6b,color:#fff
style B fill:#ffd43b,color:#000
style D fill:#ffd43b,color:#000
style F fill:#ffd43b,color:#000
style H fill:#ffd43b,color:#000
style I fill:#ffd43b,color:#000
style J fill:#51cf66,color:#fff
style K fill:#51cf66,color:#fff
style L fill:#ffd43b,color:#000
style M fill:#51cf66,color:#fff
style N fill:#51cf66,color:#fff
style O fill:#ffd43b,color:#000
style P fill:#51cf66,color:#fff
style Q fill:#51cf66,color:#fff
style R fill:#74c0fc,color:#fff
style S fill:#b197fc,color:#fff
</div>
<div class="color-legend">
<span><span class="color-box" style="background:#ff6b6b;"></span>Triggers & Conditions</span>
<span><span class="color-box" style="background:#ffd43b;"></span>Catalysts & Enzymes</span>
<span><span class="color-box" style="background:#51cf66;"></span>Chemical Processing</span>
<span><span class="color-box" style="background:#74c0fc;"></span>Intermediates</span>
<span><span class="color-box" style="background:#b197fc;"></span>Products</span>
</div>
</div>
</div>
<!-- Process 6: Circadian Rhythms -->
<div class="process-item" id="circadian-rhythms">
<h3>6. Circadian Rhythms</h3>
<p>Detailed analysis of D. melanogaster Circadian Rhythms using the Programming Framework, revealing computational logic and regulatory patterns for 24-hour cycles.</p>
<div class="mermaid-container">
<div class="mermaid">
graph TD
%% Circadian Components
A[Light Input] --> B[Clock Genes]
C[Period Gene] --> D[Timeless Gene]
E[Clock Gene] --> F[Cycle Gene]
G[Feedback Loops] --> H[Rhythm Generation]
%% Clock Genes
B --> I[PER/TIM Complex]
I --> J[Nuclear Entry]
J --> K[Gene Repression]
%% Feedback Regulation
D --> L[CLK/CYC Complex]
L --> M[Gene Activation]
M --> N[PER/TIM Synthesis]
%% Light Entrainment
F --> O[Cryptochrome]
O --> P[Light Sensing]
P --> Q[Phase Reset]
%% Integration
K --> R[Circadian Program]
N --> R
Q --> R
H --> R
R --> S[24-Hour Rhythm]
%% Styling - Programming Framework Colors
style A fill:#ff6b6b,color:#fff
style C fill:#ff6b6b,color:#fff
style E fill:#ff6b6b,color:#fff
style G fill:#ff6b6b,color:#fff
style B fill:#ffd43b,color:#000
style D fill:#ffd43b,color:#000
style F fill:#ffd43b,color:#000
style H fill:#ffd43b,color:#000
style I fill:#ffd43b,color:#000
style J fill:#51cf66,color:#fff
style K fill:#51cf66,color:#fff
style L fill:#ffd43b,color:#000
style M fill:#51cf66,color:#fff
style N fill:#51cf66,color:#fff
style O fill:#ffd43b,color:#000
style P fill:#51cf66,color:#fff
style Q fill:#51cf66,color:#fff
style R fill:#74c0fc,color:#fff
style S fill:#b197fc,color:#fff
</div>
<div class="color-legend">
<span><span class="color-box" style="background:#ff6b6b;"></span>Triggers & Conditions</span>
<span><span class="color-box" style="background:#ffd43b;"></span>Catalysts & Enzymes</span>
<span><span class="color-box" style="background:#51cf66;"></span>Chemical Processing</span>
<span><span class="color-box" style="background:#74c0fc;"></span>Intermediates</span>
<span><span class="color-box" style="background:#b197fc;"></span>Products</span>
</div>
</div>
</div>
<!-- Process 7: Learning & Memory -->
<div class="process-item" id="learning-memory">
<h3>7. Learning & Memory</h3>
<p>Detailed analysis of D. melanogaster Learning & Memory using the Programming Framework, revealing computational logic and regulatory patterns for behavioral plasticity.</p>
<div class="mermaid-container">
<div class="mermaid">
graph TD
%% Learning Components
A[Experience] --> B[Neural Plasticity]
C[cAMP Signaling] --> D[Memory Formation]
E[Mushroom Bodies] --> F[Memory Storage]
G[Retrieval] --> H[Behavioral Change]
%% Neural Plasticity
B --> I[Synaptic Changes]
I --> J[Neural Circuits]
J --> K[Circuit Modification]
%% cAMP Signaling
D --> L[dunce Gene]
L --> M[rutabaga Gene]
M --> N[cAMP Production]
%% Memory Storage
F --> O[Short-term Memory]
O --> P[Long-term Memory]
P --> Q[Memory Consolidation]
%% Integration
K --> R[Learning Program]
N --> R
Q --> R
H --> R
R --> S[Behavioral Adaptation]
%% Styling - Programming Framework Colors
style A fill:#ff6b6b,color:#fff
style C fill:#ff6b6b,color:#fff
style E fill:#ff6b6b,color:#fff
style G fill:#ff6b6b,color:#fff
style B fill:#ffd43b,color:#000
style D fill:#ffd43b,color:#000
style F fill:#ffd43b,color:#000
style H fill:#ffd43b,color:#000
style I fill:#ffd43b,color:#000
style J fill:#51cf66,color:#fff
style K fill:#51cf66,color:#fff
style L fill:#ffd43b,color:#000
style M fill:#51cf66,color:#fff
style N fill:#51cf66,color:#fff
style O fill:#ffd43b,color:#000
style P fill:#51cf66,color:#fff
style Q fill:#51cf66,color:#fff
style R fill:#74c0fc,color:#fff
style S fill:#b197fc,color:#fff
</div>
<div class="color-legend">
<span><span class="color-box" style="background:#ff6b6b;"></span>Triggers & Conditions</span>
<span><span class="color-box" style="background:#ffd43b;"></span>Catalysts & Enzymes</span>
<span><span class="color-box" style="background:#51cf66;"></span>Chemical Processing</span>
<span><span class="color-box" style="background:#74c0fc;"></span>Intermediates</span>
<span><span class="color-box" style="background:#b197fc;"></span>Products</span>
</div>
</div>
</div>
<!-- Process 8: Genetic Regulation -->
<div class="process-item" id="genetic-regulation">
<h3>8. Genetic Regulation</h3>
<p>Detailed analysis of D. melanogaster Genetic Regulation using the Programming Framework, revealing computational logic and regulatory patterns for gene expression control.</p>
<div class="mermaid-container">
<div class="mermaid">
graph TD
%% Regulation Components
A[Transcription Factors] --> B[Gene Expression]
C[Epigenetic Control] --> D[Chromatin Modification]
E[MicroRNAs] --> F[Post-transcriptional Control]
G[Alternative Splicing] --> H[Protein Diversity]
%% Transcription Control
B --> I[Enhancer Binding]
I --> J[Promoter Activation]
J --> K[Gene Transcription]
%% Epigenetic Control
D --> L[Histone Modification]
L --> M[DNA Methylation]
M --> N[Chromatin State]
%% MicroRNA Control
F --> O[miRNA Synthesis]
O --> P[Target Recognition]
P --> Q[mRNA Degradation]
%% Integration
K --> R[Regulation Program]
N --> R
Q --> R
H --> R
R --> S[Gene Expression Control]
%% Styling - Programming Framework Colors
style A fill:#ff6b6b,color:#fff
style C fill:#ff6b6b,color:#fff
style E fill:#ff6b6b,color:#fff
style G fill:#ff6b6b,color:#fff
style B fill:#ffd43b,color:#000
style D fill:#ffd43b,color:#000
style F fill:#ffd43b,color:#000
style H fill:#ffd43b,color:#000
style I fill:#ffd43b,color:#000
style J fill:#51cf66,color:#fff
style K fill:#51cf66,color:#fff
style L fill:#ffd43b,color:#000
style M fill:#51cf66,color:#fff
style N fill:#51cf66,color:#fff
style O fill:#ffd43b,color:#000
style P fill:#51cf66,color:#fff
style Q fill:#51cf66,color:#fff
style R fill:#74c0fc,color:#fff
style S fill:#b197fc,color:#fff
</div>
<div class="color-legend">
<span><span class="color-box" style="background:#ff6b6b;"></span>Triggers & Conditions</span>
<span><span class="color-box" style="background:#ffd43b;"></span>Catalysts & Enzymes</span>
<span><span class="color-box" style="background:#51cf66;"></span>Chemical Processing</span>
<span><span class="color-box" style="background:#74c0fc;"></span>Intermediates</span>
<span><span class="color-box" style="background:#b197fc;"></span>Products</span>
</div>
</div>
</div>
<div class="footer">
<p><strong>Generated using the Programming Framework methodology</strong></p>
<p>This batch demonstrates the computational nature of D. melanogaster development and genetics systems</p>
<p>Each flowchart preserves maximum detail through optimized Mermaid configuration</p>
<p><em>Batch 01 of 8: Development & Genetics</em></p>
</div>
</div>
</div>
<script>
mermaid.initialize({
startOnLoad: true,
theme: 'default',
flowchart: {
useMaxWidth: false,
htmlLabels: true,
curve: 'linear',
nodeSpacing: 30,
rankSpacing: 40,
padding: 10
},
themeVariables: {
fontFamily: 'Arial, sans-serif',
fontSize: '14px',
primaryColor: '#ff6b6b',
lineColor: '#333333',
secondaryColor: '#feca57',
tertiaryColor: '#4ecdc4'
}
});
</script>
</body>
</html>
|