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developmental_decision_systems_batch01_cell_fate_choice.html CHANGED
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  <span class="stat-label">Categories</span>
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- <span class="stat-number">100%</span>
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  <span class="stat-label">Categories</span>
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+ <span class="stat-number">Complete</span>
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evolutionary_computing_systems_batch01_adaptive_evolution.html CHANGED
@@ -287,7 +287,6 @@ graph TD
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  <h3>2. Mutation Generation</h3>
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  <div class="mermaid">
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- <div class="mermaid">
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  graph TD
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  A[DNA Replication] --> B[Replication Errors]
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  B --> C[Point Mutations]
@@ -328,12 +327,10 @@ graph TD
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  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style O fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style P fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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- </div>
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  </div>
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  <h3>3. Genetic Drift</h3>
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  <div class="mermaid">
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- <div class="mermaid">
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  graph TD
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  A[Small Population] --> B[Random Sampling]
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  B --> C[Allele Frequency Changes]
@@ -367,12 +364,10 @@ graph TD
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  style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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- </div>
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  </div>
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  <h3>4. Adaptive Evolution</h3>
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  <div class="mermaid">
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- <div class="mermaid">
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  graph TD
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  A[Environmental Change] --> B[Selection Pressure]
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  B --> C[Phenotypic Variation]
@@ -409,12 +404,10 @@ graph TD
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  style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style O fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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- </div>
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  </div>
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  <h3>5. Co-evolutionary Arms Race</h3>
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  <div class="mermaid">
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- <div class="mermaid">
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  graph TD
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  A[Host-Pathogen Interaction] --> B[Host Defense Evolution]
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  A --> C[Pathogen Counter-Evolution]
@@ -451,12 +444,10 @@ graph TD
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  style L fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
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  style M fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
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  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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- </div>
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  </div>
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  <h3>6. Sexual Selection</h3>
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  <div class="mermaid">
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- <div class="mermaid">
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  graph TD
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  A[Mating Competition] --> B[Sexual Traits]
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  B --> C[Mate Choice]
@@ -490,12 +481,10 @@ graph TD
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  style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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- </div>
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  </div>
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  <h3>7. Population Bottleneck Recovery</h3>
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  <div class="mermaid">
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- <div class="mermaid">
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  graph TD
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  A[Population Bottleneck] --> B[Genetic Diversity Loss]
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  B --> C[Inbreeding Depression]
@@ -530,12 +519,10 @@ graph TD
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  style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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- </div>
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  </div>
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  <h3>8. Speciation Decision Tree</h3>
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  <div class="mermaid">
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- <div class="mermaid">
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  graph TD
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  A[Population Isolation] --> B{Isolation Type?}
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  B -->|Geographic| C[Allopatric Speciation]
@@ -575,7 +562,6 @@ graph TD
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  style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style N fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
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  style O fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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- </div>
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  </div>
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  <div class="color-key">
 
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  <h3>2. Mutation Generation</h3>
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  <div class="mermaid">
 
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  graph TD
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  A[DNA Replication] --> B[Replication Errors]
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  B --> C[Point Mutations]
 
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  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style O fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style P fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
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  </div>
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  <h3>3. Genetic Drift</h3>
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  <div class="mermaid">
 
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  graph TD
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  A[Small Population] --> B[Random Sampling]
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  B --> C[Allele Frequency Changes]
 
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  style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
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  </div>
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  <h3>4. Adaptive Evolution</h3>
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  <div class="mermaid">
 
371
  graph TD
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  A[Environmental Change] --> B[Selection Pressure]
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  B --> C[Phenotypic Variation]
 
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  style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style O fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
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  </div>
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409
  <h3>5. Co-evolutionary Arms Race</h3>
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  <div class="mermaid">
 
411
  graph TD
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  A[Host-Pathogen Interaction] --> B[Host Defense Evolution]
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  A --> C[Pathogen Counter-Evolution]
 
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  style L fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
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  style M fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
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  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
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  </div>
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  <h3>6. Sexual Selection</h3>
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  <div class="mermaid">
 
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  graph TD
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  A[Mating Competition] --> B[Sexual Traits]
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  B --> C[Mate Choice]
 
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  style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
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  </div>
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  <h3>7. Population Bottleneck Recovery</h3>
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  <div class="mermaid">
 
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  graph TD
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  A[Population Bottleneck] --> B[Genetic Diversity Loss]
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  B --> C[Inbreeding Depression]
 
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  style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
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  </div>
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  <h3>8. Speciation Decision Tree</h3>
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  <div class="mermaid">
 
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  graph TD
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  A[Population Isolation] --> B{Isolation Type?}
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  B -->|Geographic| C[Allopatric Speciation]
 
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  style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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  style N fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
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  style O fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
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  </div>
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  <div class="color-key">
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@@ -4,6 +4,7 @@
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@@ -174,6 +175,68 @@
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  <a href="README.md" class="cta-button">📋 View Complete Collections</a>
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  <div class="main-content">
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  <div class="section">
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  <h2>🧪 Experimental Validation Protocols</h2>
@@ -417,5 +584,29 @@
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  <p><em>Generated using the Programming Framework methodology</em></p>
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  <p><em>This project demonstrates the universal computational nature of biological systems across viral, bacterial, and eukaryotic kingdoms.</em></p>
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  <meta charset="UTF-8">
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  <meta name="viewport" content="width=device-width, initial-scale=1.0">
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  <title>Genome Logic Modeling Project (GLMP) - Home</title>
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+ text-align: center;
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+ padding: 5px;
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+ border-radius: 3px;
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+ }
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+
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+ .chart-red { background: #ff6b6b; color: white; }
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+ .chart-yellow { background: #ffd43b; color: black; }
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+ .chart-green { background: #51cf66; color: white; }
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+ .chart-blue { background: #74c0fc; color: white; }
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+ .chart-violet { background: #b197fc; color: white; }
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+
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  .footer {
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  text-align: center;
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  margin-top: 40px;
 
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  flex-direction: column;
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  }
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+
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+ .chart-container {
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+ max-width: 95%;
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+ padding: 1rem;
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+ }
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+
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+ .featured-chart-section {
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  </head>
 
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  <a href="README.md" class="cta-button">📋 View Complete Collections</a>
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  </div>
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+ <div class="featured-chart-section">
319
+ <h3>🧬 Featured Example: Bacterial Implementation of Viral Decision Logic</h3>
320
+ <p class="chart-description">This flowchart demonstrates how viral lysogeny decision logic can be implemented in bacterial cells, showing the universal computational patterns that exist across biological kingdoms. The system processes multiple environmental inputs to make optimal survival decisions.</p>
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+
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+ <div class="chart-container">
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+ <div class="mermaid">
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+ graph TD
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+ A[Host Stress Signal] --> B{Stress Level?}
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+ C[Nutrient Availability] --> D{Nutrient Level?}
327
+ E[Cell Density] --> F{Density Level?}
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+
329
+ B -->|High| G[High Stress Response]
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+ B -->|Low| H[Low Stress Response]
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+ D -->|Low| I[Nutrient Limitation]
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+ D -->|High| J[Nutrient Sufficient]
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+ F -->|High| K[High Density]
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+ F -->|Low| L[Low Density]
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+
336
+ G --> M[CI-like Repressor Production]
337
+ H --> N[Cro-like Activator Production]
338
+ I --> O[Lysogeny Signal]
339
+ J --> P[Lysis Signal]
340
+ K --> Q[Quorum Signal]
341
+ L --> R[No Quorum]
342
+
343
+ M --> S[CI-like Auto-regulation]
344
+ N --> T[Cro-like Auto-regulation]
345
+ O --> U[Lysogeny Decision]
346
+ P --> V[Lysis Decision]
347
+ Q --> W[Collective Decision]
348
+ R --> X[Individual Decision]
349
+
350
+ U --> Y[Lysogeny State]
351
+ V --> Z[Lysis State]
352
+ W --> AA[Population Response]
353
+ X --> BB[Individual Response]
354
+
355
+ Y --> CC[Growth Mode]
356
+ Z --> DD[Dormancy Mode]
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+ AA --> EE[Coordinated Response]
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+ BB --> FF[Independent Response]
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+
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+ style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
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+ style C fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
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+ style E fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
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+ style B fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
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+ style D fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
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+ style F fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
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+ style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
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+ style H fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
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+ style I fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
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+ style K fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
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+ style L fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
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+ style Y fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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+ style Z fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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+ style CC fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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+ style FF fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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+ </div>
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+ </div>
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+
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+ <div class="chart-color-key">
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+ <div class="chart-color-item chart-red">🔴 Triggers & Conditions</div>
397
+ <div class="chart-color-item chart-yellow">🟡 Catalysts & Enzymes</div>
398
+ <div class="chart-color-item chart-green">🟢 Chemical Processing</div>
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+ <div class="chart-color-item chart-blue">🔵 Intermediates</div>
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+ <div class="chart-color-item chart-violet">🟣 Products</div>
401
+ </div>
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+
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+ <div class="chart-caption">
404
+ <strong>Computational Logic:</strong> Multi-input decision system with competitive inhibition (CI-like vs Cro-like), demonstrating threshold-based responses to environmental conditions. This example shows how viral decision logic can be implemented in bacterial systems, validating the Programming Framework's prediction of universal computational patterns across biological kingdoms.
405
+ </div>
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+ </div>
407
+
408
  <div class="main-content">
409
  <div class="section">
410
  <h2>🧪 Experimental Validation Protocols</h2>
 
584
  <p><em>Generated using the Programming Framework methodology</em></p>
585
  <p><em>This project demonstrates the universal computational nature of biological systems across viral, bacterial, and eukaryotic kingdoms.</em></p>
586
  </div>
587
+
588
+ <script>
589
+ mermaid.initialize({
590
+ startOnLoad: true,
591
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592
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593
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+ </script>
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  </body>
612
  </html>
information_processing_systems_batch01_signal_integration.html CHANGED
@@ -284,246 +284,180 @@ graph TD
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  <h2>🧠 Complete Information Processing Flowcharts</h2>
286
 
287
- <h3>2. Noise Filtering</h3>
288
  <div class="mermaid">
289
- <div class="mermaid">
290
  graph TD
291
- A[Noisy Signal Input] --> B[Signal Detection]
292
- B --> C[Noise Assessment]
293
- C --> D{Signal-to-Noise Ratio?}
294
- D -->|High| E[Signal Processing]
295
- D -->|Low| F[Noise Filtering]
296
-
297
- E --> G[Direct Output]
298
- F --> H[Filter Application]
299
 
300
- H --> I[Filtered Signal]
301
- I --> J[Signal Enhancement]
302
- J --> K[Clean Output]
303
 
304
- G --> L[Information Processing]
305
- K --> L
 
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307
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
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  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
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- style D fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
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  style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
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- style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
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- style G fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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- style H fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
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- style I fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
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  style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
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  style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
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- style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
319
- </div>
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  </div>
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322
- <h3>3. Pattern Recognition</h3>
323
  <div class="mermaid">
324
- <div class="mermaid">
325
  graph TD
326
- A[Pattern Input] --> B[Feature Extraction]
327
- B --> C[Pattern Analysis]
328
- C --> D{Pattern Match?}
329
- D -->|Yes| E[Pattern Recognition]
330
- D -->|No| F[Pattern Learning]
331
 
332
- E --> G[Known Pattern Response]
333
- F --> H[New Pattern Storage]
 
334
 
335
- G --> I[Predictive Response]
336
- H --> J[Pattern Database Update]
337
 
338
- I --> K[Behavioral Output]
339
- J --> L[Learning Enhancement]
340
 
341
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
342
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
343
- style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
344
- style D fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
345
- style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
346
- style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
347
- style G fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
348
- style H fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
349
- style I fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
350
- style J fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
351
  style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
352
  style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
353
- </div>
354
  </div>
355
 
356
- <h3>4. Signal Amplification</h3>
357
  <div class="mermaid">
358
- <div class="mermaid">
359
  graph TD
360
- A[Weak Signal] --> B[Signal Detection]
361
- B --> C[Amplification Cascade]
362
- C --> D[Signal Multiplication]
363
- D --> E[Amplified Output]
364
- E --> F[Response Generation]
365
-
366
- F --> G{Amplification Sufficient?}
367
- G -->|Yes| H[Response Execution]
368
- G -->|No| I[Further Amplification]
369
 
370
- I --> C
371
- H --> J[System Response]
 
372
 
373
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
374
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
375
  style C fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
376
  style D fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
377
- style E fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
378
  style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
379
- style G fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
380
  style H fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
381
- style I fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
382
- style J fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
383
- </div>
384
  </div>
385
 
386
- <h3>5. Memory Storage</h3>
387
  <div class="mermaid">
388
- <div class="mermaid">
389
  graph TD
390
- A[Information Input] --> B[Memory Encoding]
391
- B --> C[Short-term Storage]
392
- C --> D{Memory Consolidation?}
393
- D -->|Yes| E[Long-term Storage]
394
- D -->|No| F[Memory Decay]
395
-
396
- E --> G[Memory Retrieval]
397
- F --> H[Information Loss]
398
-
399
- G --> I[Memory Access]
400
- H --> I
401
-
402
- I --> J{Memory Available?}
403
- J -->|Yes| K[Memory Recall]
404
- J -->|No| L[Memory Reconstruction]
405
 
406
- K --> M[Information Output]
407
- L --> N[Partial Recall]
 
408
 
409
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
410
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
411
  style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
412
- style D fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
413
- style E fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
414
- style F fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
415
- style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
416
  style H fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
417
- style I fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
418
- style J fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
419
- style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
420
- style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
421
- style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
422
- style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
423
- </div>
424
  </div>
425
 
426
- <h3>6. Error Detection</h3>
427
  <div class="mermaid">
428
- <div class="mermaid">
429
  graph TD
430
- A[Data Input] --> B[Error Checking]
431
- B --> C{Error Detected?}
432
- C -->|Yes| D[Error Correction]
433
- C -->|No| E[Data Processing]
434
-
435
- D --> F[Error Repair]
436
- E --> G[Data Validation]
437
 
438
- F --> H[Corrected Data]
439
- G --> I[Validated Data]
440
-
441
- H --> J[Data Output]
442
- I --> J
443
-
444
- J --> K[System Continuation]
445
 
446
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
447
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
448
- style C fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
449
  style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
450
- style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
451
  style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
452
  style G fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
453
- style H fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
454
- style I fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
455
- style J fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
456
- style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
457
- </div>
458
  </div>
459
 
460
- <h3>7. Adaptive Filtering</h3>
461
  <div class="mermaid">
462
- <div class="mermaid">
463
  graph TD
464
- A[Signal Input] --> B[Filter Assessment]
465
- B --> C[Filter Performance]
466
- C --> D{Filter Optimal?}
467
- D -->|Yes| E[Current Filter]
468
- D -->|No| F[Filter Adjustment]
469
-
470
- E --> G[Filtered Output]
471
- F --> H[Filter Optimization]
472
-
473
- H --> I[New Filter Parameters]
474
- I --> J[Filter Application]
475
- J --> K[Improved Output]
476
 
477
- G --> L[Information Processing]
478
- K --> L
 
479
 
480
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
481
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
482
- style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
483
- style D fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
484
- style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
485
- style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
486
- style G fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
487
- style H fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
488
- style I fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
489
- style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
490
- style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
491
- style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
492
- </div>
493
  </div>
494
 
495
- <h3>8. Information Compression</h3>
496
  <div class="mermaid">
497
- <div class="mermaid">
498
  graph TD
499
- A[Information Input] --> B[Redundancy Analysis]
500
- B --> C[Pattern Identification]
501
- C --> D[Compression Algorithm]
502
- D --> E[Compressed Data]
503
- E --> F[Storage Optimization]
504
 
505
- F --> G{Compression Efficient?}
506
- G -->|Yes| H[Compressed Storage]
507
- G -->|No| I[Algorithm Adjustment]
508
 
509
- I --> D
510
- H --> J[Information Retrieval]
511
- J --> K[Decompression]
512
- K --> L[Original Information]
513
 
514
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
515
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
516
  style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
517
  style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
518
- style E fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
519
  style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
520
- style G fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
521
  style H fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
522
- style I fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
523
- style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
524
- style K fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
525
- style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
526
- </div>
527
  </div>
528
 
529
  <div class="color-key">
 
284
 
285
  <h2>🧠 Complete Information Processing Flowcharts</h2>
286
 
287
+ <h3>2. Signal Amplification</h3>
288
  <div class="mermaid">
 
289
  graph TD
290
+ A[Weak Input Signal] --> B[Signal Detection]
291
+ B --> C[Receptor Activation]
292
+ C --> D[Second Messenger Production]
293
+ D --> E[Enzyme Cascade]
 
 
 
 
294
 
295
+ E --> F[Signal Amplification]
296
+ F --> G[Multiple Outputs]
297
+ G --> H[Response Amplification]
298
 
299
+ H --> I[Enhanced Response]
300
+ I --> J[Signal Termination]
301
+ J --> K[System Reset]
302
 
303
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
304
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
305
+ style C fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
306
+ style D fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
307
  style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
308
+ style F fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
309
+ style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
310
+ style H fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
311
+ style I fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
312
  style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
313
  style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
 
314
  </div>
315
 
316
+ <h3>3. Noise Filtering</h3>
317
  <div class="mermaid">
 
318
  graph TD
319
+ A[Noisy Input] --> B[Signal Processing]
320
+ B --> C[Noise Detection]
321
+ C --> D[Filter Application]
322
+ D --> E[Signal Extraction]
 
323
 
324
+ E --> F[Clean Signal]
325
+ F --> G[Threshold Check]
326
+ G --> H{Signal Valid?}
327
 
328
+ H -->|Yes| I[Signal Transmission]
329
+ H -->|No| J[Signal Rejection]
330
 
331
+ I --> K[Response Generation]
332
+ J --> L[No Response]
333
 
334
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
335
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
336
+ style C fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
337
+ style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
338
+ style E fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
339
+ style F fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
340
+ style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
341
+ style H fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
342
+ style I fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
343
+ style J fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
344
  style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
345
  style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
346
  </div>
347
 
348
+ <h3>4. Cross-Talk Integration</h3>
349
  <div class="mermaid">
 
350
  graph TD
351
+ A[Multiple Signals] --> B[Signal Convergence]
352
+ B --> C[Cross-Talk Detection]
353
+ C --> D[Signal Integration]
354
+ D --> E[Combined Response]
 
 
 
 
 
355
 
356
+ E --> F[Response Modulation]
357
+ F --> G[Output Generation]
358
+ G --> H[System Response]
359
 
360
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
361
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
362
  style C fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
363
  style D fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
364
+ style E fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
365
  style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
366
+ style G fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
367
  style H fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
 
 
368
  </div>
369
 
370
+ <h3>5. Feedback Regulation</h3>
371
  <div class="mermaid">
 
372
  graph TD
373
+ A[Input Signal] --> B[System Response]
374
+ B --> C[Output Generation]
375
+ C --> D[Feedback Signal]
376
+ D --> E[Response Modulation]
 
 
 
 
 
 
 
 
 
 
 
377
 
378
+ E --> F[System Adjustment]
379
+ F --> G[Homeostasis]
380
+ G --> H[Stable State]
381
 
382
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
383
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
384
  style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
385
+ style D fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
386
+ style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
387
+ style F fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
388
+ style G fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
389
  style H fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
 
 
 
 
 
 
390
  </div>
391
 
392
+ <h3>6. Signal Transduction</h3>
393
  <div class="mermaid">
 
394
  graph TD
395
+ A[Extracellular Signal] --> B[Receptor Binding]
396
+ B --> C[Conformational Change]
397
+ C --> D[Intracellular Signaling]
398
+ D --> E[Second Messengers]
 
 
 
399
 
400
+ E --> F[Protein Kinases]
401
+ F --> G[Transcription Factors]
402
+ G --> H[Gene Expression]
403
+ H --> I[Cellular Response]
 
 
 
404
 
405
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
406
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
407
+ style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
408
  style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
409
+ style E fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
410
  style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
411
  style G fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
412
+ style H fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
413
+ style I fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
 
 
414
  </div>
415
 
416
+ <h3>7. Information Processing</h3>
417
  <div class="mermaid">
 
418
  graph TD
419
+ A[Input Information] --> B[Information Processing]
420
+ B --> C[Decision Making]
421
+ C --> D[Response Selection]
422
+ D --> E[Output Generation]
 
 
 
 
 
 
 
 
423
 
424
+ E --> F[System Response]
425
+ F --> G[Information Storage]
426
+ G --> H[Learning]
427
 
428
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
429
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
430
+ style C fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
431
+ style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
432
+ style E fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
433
+ style F fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
434
+ style G fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
435
+ style H fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
 
 
 
 
436
  </div>
437
 
438
+ <h3>8. Signal Integration</h3>
439
  <div class="mermaid">
 
440
  graph TD
441
+ A[Multiple Inputs] --> B[Signal Integration]
442
+ B --> C[Weighted Sum]
443
+ C --> D[Threshold Check]
444
+ D --> E{Threshold Exceeded?}
 
445
 
446
+ E -->|Yes| F[Response Generation]
447
+ E -->|No| G[No Response]
 
448
 
449
+ F --> H[Output Signal]
450
+ G --> I[System Quiescence]
 
 
451
 
452
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
453
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
454
  style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
455
  style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
456
+ style E fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
457
  style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
458
+ style G fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
459
  style H fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
460
+ style I fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
 
 
 
461
  </div>
462
 
463
  <div class="color-key">
metabolic_decision_systems_batch01_energy_balance.html CHANGED
@@ -225,7 +225,7 @@
225
  <span class="stat-label">Categories</span>
226
  </div>
227
  <div class="stat">
228
- <span class="stat-number">100%</span>
229
  <span class="stat-label">Complete</span>
230
  </div>
231
  </div>
 
225
  <span class="stat-label">Categories</span>
226
  </div>
227
  <div class="stat">
228
+ <span class="stat-number">Complete</span>
229
  <span class="stat-label">Complete</span>
230
  </div>
231
  </div>
neural_decision_systems_batch01_winner_take_all.html CHANGED
@@ -225,7 +225,7 @@
225
  <span class="stat-label">Categories</span>
226
  </div>
227
  <div class="stat">
228
- <span class="stat-number">100%</span>
229
  <span class="stat-label">Complete</span>
230
  </div>
231
  </div>
 
225
  <span class="stat-label">Categories</span>
226
  </div>
227
  <div class="stat">
228
+ <span class="stat-number">Complete</span>
229
  <span class="stat-label">Complete</span>
230
  </div>
231
  </div>
plant_decision_systems_batch01_photomorphogenesis.html CHANGED
@@ -225,7 +225,7 @@
225
  <span class="stat-label">Categories</span>
226
  </div>
227
  <div class="stat">
228
- <span class="stat-number">100%</span>
229
  <span class="stat-label">Complete</span>
230
  </div>
231
  </div>
 
225
  <span class="stat-label">Categories</span>
226
  </div>
227
  <div class="stat">
228
+ <span class="stat-number">Complete</span>
229
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230
  </div>
231
  </div>
synthetic_biology_circuits_batch01_logic_gates.html CHANGED
@@ -273,7 +273,6 @@ graph TD
273
 
274
  <h3>2. OR Logic Gate</h3>
275
  <div class="mermaid">
276
- <div class="mermaid">
277
  graph TD
278
  A[Input A Signal] --> B{Input A Present?}
279
  C[Input B Signal] --> D{Input B Present?}
@@ -320,7 +319,6 @@ graph TD
320
 
321
  <h3>3. NOT Logic Gate</h3>
322
  <div class="mermaid">
323
- <div class="mermaid">
324
  graph TD
325
  A[Input Signal] --> B{Input Present?}
326
  B -->|Yes| C[Repressor Active]
@@ -355,7 +353,6 @@ graph TD
355
 
356
  <h3>4. NAND Logic Gate</h3>
357
  <div class="mermaid">
358
- <div class="mermaid">
359
  graph TD
360
  A[Input A Signal] --> B{Input A Present?}
361
  C[Input B Signal] --> D{Input B Present?}
@@ -403,7 +400,6 @@ graph TD
403
 
404
  <h3>5. Toggle Switch</h3>
405
  <div class="mermaid">
406
- <div class="mermaid">
407
  graph TD
408
  A[Toggle Signal] --> B{Current State?}
409
  B -->|OFF| C[Repressor Inactive]
@@ -441,7 +437,6 @@ graph TD
441
 
442
  <h3>6. Oscillator Circuit</h3>
443
  <div class="mermaid">
444
- <div class="mermaid">
445
  graph TD
446
  A[Oscillator Initiation] --> B[Gene A Expression]
447
  B --> C[Protein A Synthesis]
@@ -483,7 +478,6 @@ graph TD
483
 
484
  <h3>7. Sensor Circuit</h3>
485
  <div class="mermaid">
486
- <div class="mermaid">
487
  graph TD
488
  A[Environmental Signal] --> B[Signal Detection]
489
  B --> C{Signal Threshold?}
@@ -512,7 +506,6 @@ graph TD
512
 
513
  <h3>8. Amplifier Circuit</h3>
514
  <div class="mermaid">
515
- <div class="mermaid">
516
  graph TD
517
  A[Weak Input Signal] --> B[Signal Detection]
518
  B --> C[Transcription Factor]
 
273
 
274
  <h3>2. OR Logic Gate</h3>
275
  <div class="mermaid">
 
276
  graph TD
277
  A[Input A Signal] --> B{Input A Present?}
278
  C[Input B Signal] --> D{Input B Present?}
 
319
 
320
  <h3>3. NOT Logic Gate</h3>
321
  <div class="mermaid">
 
322
  graph TD
323
  A[Input Signal] --> B{Input Present?}
324
  B -->|Yes| C[Repressor Active]
 
353
 
354
  <h3>4. NAND Logic Gate</h3>
355
  <div class="mermaid">
 
356
  graph TD
357
  A[Input A Signal] --> B{Input A Present?}
358
  C[Input B Signal] --> D{Input B Present?}
 
400
 
401
  <h3>5. Toggle Switch</h3>
402
  <div class="mermaid">
 
403
  graph TD
404
  A[Toggle Signal] --> B{Current State?}
405
  B -->|OFF| C[Repressor Inactive]
 
437
 
438
  <h3>6. Oscillator Circuit</h3>
439
  <div class="mermaid">
 
440
  graph TD
441
  A[Oscillator Initiation] --> B[Gene A Expression]
442
  B --> C[Protein A Synthesis]
 
478
 
479
  <h3>7. Sensor Circuit</h3>
480
  <div class="mermaid">
 
481
  graph TD
482
  A[Environmental Signal] --> B[Signal Detection]
483
  B --> C{Signal Threshold?}
 
506
 
507
  <h3>8. Amplifier Circuit</h3>
508
  <div class="mermaid">
 
509
  graph TD
510
  A[Weak Input Signal] --> B[Signal Detection]
511
  B --> C[Transcription Factor]
temporal_programming_systems_batch01_cell_cycle.html CHANGED
@@ -291,7 +291,6 @@ graph TD
291
 
292
  <h3>2. G2/M Checkpoint Decision</h3>
293
  <div class="mermaid">
294
- <div class="mermaid">
295
  graph TD
296
  A[G2 Phase Entry] --> B[DNA Replication Check]
297
  B --> C{Replication Complete?}
@@ -299,22 +298,23 @@ graph TD
299
  C -->|Yes| E[DNA Damage Check]
300
 
301
  D --> B
302
- E --> F{DNA Damage Present?}
303
- F -->|Yes| G[Damage Repair]
304
- F -->|No| H[Chromosome Condensation]
305
 
306
- G --> I[Repair Completion]
307
- I --> F
308
- H --> J[Spindle Assembly Check]
 
309
 
310
- J --> K{Spindle Ready?}
311
- K -->|No| L[Spindle Formation]
312
- K -->|Yes| M[Mitosis Initiation]
313
 
314
- L --> J
315
- M --> N[Metaphase Entry]
316
- N --> O[Chromosome Alignment]
317
- O --> P[Anaphase Trigger]
318
 
319
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
320
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
@@ -324,85 +324,126 @@ graph TD
324
  style F fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
325
  style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
326
  style H fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
327
- style I fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
328
- style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
329
- style K fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
330
- style L fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
331
- style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
332
  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
333
- style O fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
334
- style P fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
335
- </div>
336
  </div>
337
 
338
- <h3>3. Spindle Assembly Checkpoint</h3>
339
  <div class="mermaid">
340
- <div class="mermaid">
341
  graph TD
342
- A[Spindle Formation] --> B[Kinetochore Assembly]
343
- B --> C[Microtubule Attachment]
344
- C --> D{All Chromosomes Attached?}
345
- D -->|No| E[Kinetochore Signaling]
346
- D -->|Yes| F[Checkpoint Satisfaction]
347
-
348
- E --> G[Mad2 Activation]
349
- G --> H[APC/C Inhibition]
350
- H --> I[Anaphase Delay]
351
- I --> C
352
-
353
- F --> J[Mad2 Inactivation]
354
- J --> K[APC/C Activation]
355
- K --> L[Securin Degradation]
356
- L --> M[Separase Activation]
357
- M --> N[Cohesin Cleavage]
358
- N --> O[Anaphase Onset]
 
 
359
 
360
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
361
- style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
362
- style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
363
- style D fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
364
  style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
365
  style F fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
366
  style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
367
- style H fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
368
  style I fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
369
  style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
370
- style K fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
371
- style L fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
372
  style M fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
373
- style N fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
374
  style O fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
375
- </div>
376
  </div>
377
 
378
- <h3>4. DNA Damage Response Timing</h3>
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
379
  <div class="mermaid">
380
- <div class="mermaid">
381
  graph TD
382
- A[DNA Damage Detection] --> B[Damage Type Assessment]
383
- B --> C{Double Strand Break?}
384
- C -->|Yes| D[ATM Activation]
385
- C -->|No| E[ATR Activation]
 
386
 
387
- D --> F[Chk2 Phosphorylation]
388
- E --> G[Chk1 Phosphorylation]
 
389
 
390
- F --> H[Cell Cycle Arrest]
391
- G --> H
392
 
393
- H --> I[DNA Repair Initiation]
394
- I --> J{Repair Type?}
395
- J -->|Homologous| K[HR Repair]
396
- J -->|Non-homologous| L[NHEJ Repair]
397
 
398
- K --> M[Repair Completion]
399
  L --> M
400
- M --> N[Damage Check]
401
- N --> O{Repair Successful?}
402
 
403
- O -->|No| P[Apoptosis]
404
- O -->|Yes| Q[Checkpoint Release]
405
- Q --> R[Cell Cycle Resumption]
406
 
407
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
408
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
@@ -410,172 +451,118 @@ graph TD
410
  style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
411
  style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
412
  style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
413
- style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
414
- style H fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
415
- style I fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
416
- style J fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
417
  style K fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
418
- style L fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
419
- style M fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
420
- style N fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
421
- style O fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
422
- style P fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
423
- style Q fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
424
- style R fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
425
- </div>
426
  </div>
427
 
428
- <h3>5. Developmental Timing</h3>
429
  <div class="mermaid">
430
- <div class="mermaid">
431
  graph TD
432
- A[Developmental Signal] --> B[Timing Gene Expression]
433
- B --> C[Developmental Clock]
434
- C --> D{Timing Threshold?}
435
- D -->|No| E[Clock Continuation]
436
- D -->|Yes| F[Stage Transition]
437
-
438
- E --> C
439
- F --> G[New Gene Expression]
440
- G --> H[Developmental Progress]
441
- H --> I{Next Stage Ready?}
442
 
443
- I -->|No| J[Stage Maintenance]
444
- I -->|Yes| K[Stage Completion]
 
445
 
446
- J --> H
447
- K --> L[Next Developmental Stage]
448
- L --> M[New Timing Program]
449
- M --> N[Developmental Continuation]
450
 
451
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
452
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
453
- style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
454
- style D fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
455
  style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
456
- style F fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
457
  style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
458
  style H fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
459
- style I fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
460
- style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
461
- style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
462
- style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
463
  style M fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
464
  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
465
- </div>
466
  </div>
467
 
468
- <h3>6. Circadian Rhythm Integration</h3>
469
  <div class="mermaid">
470
- <div class="mermaid">
471
  graph TD
472
- A[Light Signal] --> B[Clock Gene Expression]
473
- B --> C[Circadian Oscillator]
474
- C --> D[Clock Protein Synthesis]
475
- D --> E[Protein Accumulation]
476
- E --> F[Feedback Inhibition]
477
- F --> G[Gene Repression]
478
- G --> H[Protein Degradation]
479
- H --> I[Repression Release]
480
- I --> B
481
 
482
- C --> J[Output Genes]
483
- J --> K[Physiological Rhythms]
484
- K --> L[Metabolic Timing]
485
- L --> M[Behavioral Timing]
486
- M --> N[Environmental Synchronization]
 
 
 
 
 
 
 
487
 
488
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
489
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
490
- style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
491
  style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
492
- style E fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
493
- style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
494
- style G fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
495
- style H fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
496
- style I fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
497
  style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
498
  style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
499
  style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
500
- style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
501
- style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
502
- </div>
503
  </div>
504
 
505
- <h3>7. Aging Clock Mechanisms</h3>
506
  <div class="mermaid">
507
- <div class="mermaid">
508
  graph TD
509
- A[Aging Signal] --> B[Telomere Shortening]
510
- B --> C[DNA Damage Accumulation]
511
- C --> D[Oxidative Stress]
512
- D --> E[Metabolic Changes]
513
- E --> F[Aging Clock Progression]
514
 
515
- F --> G{Clock Threshold?}
516
- G -->|No| H[Clock Continuation]
517
- G -->|Yes| I[Senescence Initiation]
 
 
518
 
519
  H --> F
520
- I --> J[Cell Cycle Arrest]
521
- J --> K[Senescence Program]
522
- K --> L[Metabolic Reprogramming]
523
- L --> M[Inflammatory Response]
524
- M --> N[Tissue Dysfunction]
525
- N --> O[Organismal Aging]
526
 
527
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
528
- style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
529
- style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
530
- style D fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
531
  style E fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
532
- style F fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
533
  style G fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
534
  style H fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
535
- style I fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
536
- style J fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
537
- style K fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
538
- style L fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
539
- style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
540
- style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
541
- style O fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
542
- </div>
543
- </div>
544
-
545
- <h3>8. Synchronization Systems</h3>
546
- <div class="mermaid">
547
- <div class="mermaid">
548
- graph TD
549
- A[Synchronization Signal] --> B[Phase Detection]
550
- B --> C[Phase Comparison]
551
- C --> D{Phase Aligned?}
552
- D -->|No| E[Phase Adjustment]
553
- D -->|Yes| F[Synchronized State]
554
-
555
- E --> G[Clock Speed Modulation]
556
- G --> H[Phase Shift]
557
- H --> I[New Phase]
558
- I --> C
559
-
560
- F --> J[Coordinated Behavior]
561
- J --> K[Population Synchrony]
562
- K --> L[Collective Timing]
563
- L --> M[Environmental Adaptation]
564
-
565
- style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
566
- style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
567
- style C fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
568
- style D fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
569
- style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
570
- style F fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
571
- style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
572
- style H fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
573
  style I fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
574
  style J fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
575
  style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
576
- style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
577
- style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
578
- </div>
579
  </div>
580
 
581
  <div class="color-key">
 
291
 
292
  <h3>2. G2/M Checkpoint Decision</h3>
293
  <div class="mermaid">
 
294
  graph TD
295
  A[G2 Phase Entry] --> B[DNA Replication Check]
296
  B --> C{Replication Complete?}
 
298
  C -->|Yes| E[DNA Damage Check]
299
 
300
  D --> B
301
+ E --> F{DNA Intact?}
302
+ F -->|No| G[DNA Repair Activation]
303
+ F -->|Yes| H[Spindle Assembly Check]
304
 
305
+ G --> I[Repair Mechanisms]
306
+ I --> J{Repair Successful?}
307
+ J -->|No| K[Apoptosis Trigger]
308
+ J -->|Yes| E
309
 
310
+ H --> L{Spindle Ready?}
311
+ L -->|No| M[Spindle Assembly]
312
+ L -->|Yes| N[Mitosis Entry]
313
 
314
+ M --> H
315
+ N --> O[Chromosome Condensation]
316
+ O --> P[Mitotic Spindle Formation]
317
+ P --> Q[Metaphase Alignment]
318
 
319
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
320
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
 
324
  style F fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
325
  style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
326
  style H fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
327
+ style I fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
328
+ style J fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
329
+ style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
330
+ style L fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
331
+ style M fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
332
  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
333
+ style O fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
334
+ style P fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
335
+ style Q fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
336
  </div>
337
 
338
+ <h3>3. M Phase Progression</h3>
339
  <div class="mermaid">
 
340
  graph TD
341
+ A[Mitosis Entry] --> B[Prophase]
342
+ B --> C[Chromosome Condensation]
343
+ C --> D[Nuclear Envelope Breakdown]
344
+ D --> E[Spindle Formation]
345
+
346
+ E --> F[Metaphase]
347
+ F --> G[Chromosome Alignment]
348
+ G --> H{Alignment Complete?}
349
+ H -->|No| G
350
+ H -->|Yes| I[Anaphase]
351
+
352
+ I --> J[Chromosome Separation]
353
+ J --> K[Telophase]
354
+ K --> L[Nuclear Reformation]
355
+ L --> M[Cytokinesis]
356
+
357
+ M --> N{Division Complete?}
358
+ N -->|No| M
359
+ N -->|Yes| O[Two Daughter Cells]
360
 
361
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
362
+ style B fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
363
+ style C fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
364
+ style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
365
  style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
366
  style F fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
367
  style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
368
+ style H fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
369
  style I fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
370
  style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
371
+ style K fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
372
+ style L fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
373
  style M fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
374
+ style N fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
375
  style O fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
376
  </div>
377
 
378
+ <h3>4. Cell Cycle Exit Decision</h3>
379
+ <div class="mermaid">
380
+ graph TD
381
+ A[G1 Phase] --> B{Cell Division Required?}
382
+ B -->|No| C[G0 Entry]
383
+ B -->|Yes| D[Growth Assessment]
384
+
385
+ C --> E[Quiescent State]
386
+ E --> F{Stimulation Signal?}
387
+ F -->|Yes| G[G1 Re-entry]
388
+ F -->|No| E
389
+
390
+ D --> H{Size Adequate?}
391
+ H -->|No| I[Growth Continuation]
392
+ H -->|Yes| J[Nutrient Check]
393
+
394
+ I --> D
395
+ J --> K{Nutrients Sufficient?}
396
+ K -->|No| L[Starvation Response]
397
+ K -->|Yes| M[Cell Cycle Continuation]
398
+
399
+ L --> N[Metabolic Adaptation]
400
+ N --> O{Environment Improved?}
401
+ O -->|Yes| J
402
+ O -->|No| P[Apoptosis]
403
+
404
+ style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
405
+ style B fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
406
+ style C fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
407
+ style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
408
+ style E fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
409
+ style F fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
410
+ style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
411
+ style H fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
412
+ style I fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
413
+ style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
414
+ style K fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
415
+ style L fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
416
+ style M fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
417
+ style N fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
418
+ style O fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
419
+ style P fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
420
+ </div>
421
+
422
+ <h3>5. DNA Damage Response</h3>
423
  <div class="mermaid">
 
424
  graph TD
425
+ A[DNA Damage] --> B[Damage Detection]
426
+ B --> C{Damage Type?}
427
+ C -->|Single Strand| D[Base Excision Repair]
428
+ C -->|Double Strand| E[Double Strand Break Repair]
429
+ C -->|Crosslink| F[Crosslink Repair]
430
 
431
+ D --> G[Repair Completion]
432
+ E --> H{Repair Pathway?}
433
+ F --> I[Crosslink Resolution]
434
 
435
+ H -->|NHEJ| J[Non-homologous End Joining]
436
+ H -->|HR| K[Homologous Recombination]
437
 
438
+ J --> L[Repair Completion]
439
+ K --> L
440
+ I --> L
 
441
 
442
+ G --> M{Repair Successful?}
443
  L --> M
 
 
444
 
445
+ M -->|Yes| N[Cell Cycle Continuation]
446
+ M -->|No| O[Apoptosis]
 
447
 
448
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
449
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
 
451
  style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
452
  style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
453
  style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
454
+ style G fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
455
+ style H fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
456
+ style I fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
457
+ style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
458
  style K fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
459
+ style L fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
460
+ style M fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
461
+ style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
462
+ style O fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
 
 
 
463
  </div>
464
 
465
+ <h3>6. Spindle Assembly Checkpoint</h3>
466
  <div class="mermaid">
 
467
  graph TD
468
+ A[Metaphase] --> B[Kinetochore Attachment]
469
+ B --> C{All Chromosomes Attached?}
470
+ C -->|No| D[Unattached Kinetochores]
471
+ C -->|Yes| E[Tension Check]
472
+
473
+ D --> F[SAC Activation]
474
+ F --> G[APC/C Inhibition]
475
+ G --> H[Metaphase Arrest]
476
+ H --> I[Re-attachment Attempt]
477
+ I --> B
478
 
479
+ E --> J{Tension Adequate?}
480
+ J -->|No| K[Tension Generation]
481
+ J -->|Yes| L[SAC Silencing]
482
 
483
+ K --> E
484
+ L --> M[APC/C Activation]
485
+ M --> N[Anaphase Entry]
 
486
 
487
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
488
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
489
+ style C fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
490
+ style D fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
491
  style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
492
+ style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
493
  style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
494
  style H fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
495
+ style I fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
496
+ style J fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
497
+ style K fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
498
+ style L fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
499
  style M fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
500
  style N fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
501
  </div>
502
 
503
+ <h3>7. Cytokinesis Timing</h3>
504
  <div class="mermaid">
 
505
  graph TD
506
+ A[Anaphase Completion] --> B[Contractile Ring Assembly]
507
+ B --> C{Ring Formation Complete?}
508
+ C -->|No| D[Ring Assembly Continuation]
509
+ C -->|Yes| E[Actomyosin Contraction]
 
 
 
 
 
510
 
511
+ D --> B
512
+ E --> F{Membrane Cleavage?}
513
+ F -->|No| G[Contraction Continuation]
514
+ F -->|Yes| H[Cell Separation]
515
+
516
+ G --> E
517
+ H --> I{Separation Complete?}
518
+ I -->|No| J[Final Cleavage]
519
+ I -->|Yes| K[Two Daughter Cells]
520
+
521
+ J --> I
522
+ K --> L[Cell Cycle Completion]
523
 
524
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
525
  style B fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
526
+ style C fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
527
  style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
528
+ style E fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
529
+ style F fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
530
+ style G fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
531
+ style H fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
532
+ style I fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
533
  style J fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
534
  style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
535
  style L fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
 
 
536
  </div>
537
 
538
+ <h3>8. Cell Cycle Synchronization</h3>
539
  <div class="mermaid">
 
540
  graph TD
541
+ A[Population Signal] --> B{Synchronization Required?}
542
+ B -->|No| C[Independent Cycling]
543
+ B -->|Yes| D[Synchronization Signal]
 
 
544
 
545
+ C --> E[Random Phase Distribution]
546
+ D --> F[Phase Alignment]
547
+ F --> G{Alignment Complete?}
548
+ G -->|No| H[Phase Adjustment]
549
+ G -->|Yes| I[Synchronized Population]
550
 
551
  H --> F
552
+ I --> J[Coordinated Division]
553
+ J --> K[Population Synchrony]
 
 
 
 
554
 
555
  style A fill:#ff6b6b,stroke:#333,stroke-width:2px,color:#fff
556
+ style B fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
557
+ style C fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
558
+ style D fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
559
  style E fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
560
+ style F fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
561
  style G fill:#ffd43b,stroke:#333,stroke-width:2px,color:#000
562
  style H fill:#51cf66,stroke:#333,stroke-width:2px,color:#fff
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
563
  style I fill:#74c0fc,stroke:#333,stroke-width:2px,color:#fff
564
  style J fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
565
  style K fill:#b197fc,stroke:#333,stroke-width:2px,color:#fff
 
 
 
566
  </div>
567
 
568
  <div class="color-key">
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